Benign neoplasm: Liver/bile ducts

CD2_BENIGN_LIVE_BILE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

1143

6. Filter based on genotype QC (FinnGen only)

1040

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4652 3169 1446
Only index persons 4204 2945 1259
Unadjusted period prevalence (%)
Whole population 0.07 0.09 0.04
Only index persons 0.09 0.11 0.05
Median age at first event (years)
Whole population 53.05 49.88 59.76
Only index persons 51.67 48.81 58.37

-FinnGen-

Key figures

All Female Male
Number of individuals 1040 755 285
Unadjusted period prevalence (%) 0.23 0.27 0.13
Median age at first event (years) 53.67 50.13 63.03

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1072
Matched controls
10720
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D13.4
ICD-10 Finland
Benign neoplasm: Liver
4503599627370496.0
307.7
943
*
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
52.4
307.7
241
59
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
25.0
282.3
209
103
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
18.3
169.1
141
88
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
16.1
137.7
122
85
R93.2
ICD-10 Finland
Abnormal findings on diagnostic imaging of liver and biliary tract
31.5
132.0
87
30
D13.5
ICD-10 Finland
Benign neoplasm: Extrahepatic bile ducts
+∞
122.3
115
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
5.1
95.1
235
558
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
13.8
62.6
59
45
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.6
49.6
542
3056
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
7.5
44.9
66
93
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
6.3
42.0
73
123
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.7
41.6
301
1371
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.0
38.5
207
804
D18.0
ICD-10 Finland
Haemangioma, any site
6.5
38.5
64
103
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
15.4
37.5
33
22
JN3AD
NOMESCO Finland
Abdominal CT examination
2.7
30.3
190
794
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
29.4
363
2046
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
2.7
29.2
175
714
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.8
25.2
137
530
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
4.5
22.7
57
133
K76.9
ICD-10 Finland
Liver disease, unspecified
7.1
21.7
33
48
UJF32
NOMESCO Finland
Coloscopy
2.0
21.0
298
1733
K76.89
ICD-10 Finland
Other specified diseases of liver
22.0
20.9
30
14
N02AX02
ATC
tramadol; systemic, rectal
1.8
18.9
470
3250
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.3
18.4
71
225
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
4.1
18.1
51
130
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
17.8
325
2036
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
6.0
17.0
30
51
JJB71
NOMESCO Finland
Laparoscopic resection of liver
50.9
17.0
20
*
A02BC02
ATC
pantoprazole; systemic
1.8
16.7
742
5969
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.2
16.2
152
751
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
4.5
16.0
39
89
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.9
15.7
74
264
A02BC05
ATC
esomeprazole; systemic
1.7
15.1
448
3195
WX402
NOMESCO Finland
General anaesthesia
1.8
15.1
268
1653
J01MA02
ATC
ciprofloxacin; systemic
1.7
15.0
406
2824
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
15.0
241
1442
K76.80
ICD-10 Finland
Hepatic cyst
11.5
14.8
27
24
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
14.6
281
1773
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
14.5
262
1622
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
12.9
13.9
24
19
R07.0
ICD-10 Finland
Pain in throat
2.3
13.6
103
465
A02BC01
ATC
omeprazole; systemic
1.7
13.4
294
1921
K30
ICD-10 Finland
Functional dyspepsia
2.0
12.9
151
808
JJ3AT
NOMESCO Finland
Cytology of liver with ultrasound guidance
50.6
12.9
15
*
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
10.6
12.8
24
23
A02BC03
ATC
lansoprazole; oral
1.7
12.7
301
2003
K86.2
ICD-10 Finland
Cyst of pancreas
6.0
12.6
22
37
8170/3-C22.0
ICD-O-3
Hepatocellular carcinoma, NOS, of liver
17.6
12.5
19
11
21150
ICD-8 Finland
Benign neoplasm of other parts of digestive system, Hepatis
+∞
12.5
12
*
Z3231
NOMESCO Finland
Registered nurse
1.7
12.3
285
1884
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.0
12.2
53
180
JN4CD
NOMESCO Finland
Very extensive body CT
3.5
12.2
42
124
JN1AE, ,
SPAT
2.7
12.0
63
238
JJB50
NOMESCO Finland
Excision of segments V, VI, VII and VIII of liver
47.2
11.9
14
*
J01DB01
ATC
cefalexin; oral
1.8
11.7
894
7881
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
12.0
11.4
20
17
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.9
11.3
161
919
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
4.3
11.3
29
69
K83.0
ICD-10 Finland
Cholangitis
5.2
11.3
23
45
JN3AE, ,
SPAT
2.7
11.3
63
246
D01
ICPC
Abdominal pain/cramps general
1.9
11.3
154
868
N02BE01
ATC
paracetamol; systemic, rectal
2.0
11.2
957
8646
D06
ICPC
Abdominal pain localized other
2.1
11.2
112
565
R4110
NOMESCO Finland
Physiotherapy
1.7
11.2
289
1959
R06.0
ICD-10 Finland
Dyspnoea
1.6
11.1
289
1961
JKA20
NOMESCO Finland
Cholecystectomy
3.7
11.0
34
93
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
10.7
10.8
20
19
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.8
10.4
159
929
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.2
10.4
86
403
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
12.2
10.4
18
15
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
10.3
135
750
D13.6
ICD-10 Finland
Benign neoplasm: Pancreas
10.7
10.3
19
18
B01AB05
ATC
enoxaparin; parenteral
1.6
10.1
311
2192
R51.80
ICD-10 Finland
Headache
1.7
10.0
195
1221
TPH07
NOMESCO Finland
Cathetrisation of artery
2.0
9.9
110
577
H53.1
ICD-10 Finland
Subjective visual disturbances
2.2
9.8
85
405
C22.9
ICD-10 Finland
Malignant neoplasm: Liver, unspecified
20.2
9.8
14
7
UJF30
NOMESCO Finland
Ileoscopy through colon
2.0
9.7
116
625
UJK12
NOMESCO Finland
Peroral cholangioscopy
55.5
9.7
11
*
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
3.3
9.6
35
107
P01AB01
ATC
metronidazole; oral, rectal
1.5
9.6
445
3426
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
9.4
460
3573
Z71.8
ICD-10 Finland
Other specified counselling
1.5
9.4
388
2909
JJA21
NOMESCO Finland
Laparoscopic biopsy of liver
17.7
9.4
14
8
C22.1
ICD-10 Finland
Malignant neoplasm: Intrahepatic bile duct carcinoma
17.7
9.4
14
8
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
9.3
151
898
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.7
9.1
170
1051
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
9.0
379
2847
130
Kela drug reimbursment
Malignant tumour
2.1
9.0
83
407
UJK02
NOMESCO Finland
ERCP
3.3
8.9
33
102
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.0
8.9
106
569
D13.9
ICD-10 Finland
Benign neoplasm: Ill-defined sites within the digestive system
24.2
8.9
12
5
Z3226
NOMESCO Finland
Physiotherapist
1.7
8.9
186
1186
SPAT1360
SPAT
Extensive global examination
2.3
8.8
68
309
K82.8
ICD-10 Finland
Other specified diseases of gallbladder
14.2
8.7
14
10
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
8.6
392
2989
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
8.6
270
1902
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
8.6
203
1336
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.9
8.5
115
646
R52.9
ICD-10 Finland
Pain, unspecified
1.9
8.4
117
663
R01AD58
ATC
fluticasone, combinations; nasal
1.5
8.3
294
2122
B01AB04
ATC
dalteparin; parenteral
2.4
8.1
56
243
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.1
8.0
77
383
XKD00
NOMESCO Finland
Uroflowmetry
1.8
7.9
115
659
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
7.9
238
1655
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.9
7.9
94
506
J01MA12
ATC
levofloxacin; systemic
1.7
7.8
174
1125
UKC02
NOMESCO Finland
Cystoscopy
1.8
7.8
134
808
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
9.5
7.8
15
16
N06AX12
ATC
bupropion; oral
1.9
7.7
95
516
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
45.3
7.7
9
*
C08CA01
ATC
amlodipine; oral
1.5
7.7
331
2483
N03AX16
ATC
[U] pregabalin
1.6
7.6
228
1586
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
4.1
7.6
20
49
H66.9
ICD-10 Finland
Otitis media, unspecified
2.0
7.5
80
413
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
10.1
7.5
14
14
M79.6
ICD-10 Finland
Pain in limb
1.4
7.5
468
3762
R05
ICPC
Cough
1.5
7.5
274
1988
M54
ICD-10 Finland
Dorsalgia
1.7
7.3
141
878
JJB30
NOMESCO Finland
Excision of two segments of liver
20.2
7.1
10
5
JAH00
NOMESCO Finland
Laparotomy
2.8
7.1
34
123
JN4AD
NOMESCO Finland
Body CT examination
1.8
7.1
106
614
R30.0
ICD-10 Finland
Dysuria
2.3
7.1
53
239
R42
ICD-10 Finland
Dizziness and giddiness
1.5
7.0
219
1533
R00.2
ICD-10 Finland
Palpitations
1.8
6.9
96
543
JAH01
NOMESCO Finland
Laparoscopy
2.2
6.9
59
281
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.7
6.9
124
758
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
2.1
6.9
61
295
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.3
6.8
51
230
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
6.2
6.8
17
28
K83.1
ICD-10 Finland
Obstruction of bile duct
3.9
6.7
19
49
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
3.3
6.7
24
73
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
2.7
6.7
35
133
D11
ICPC
Diarrhoea
1.7
6.6
137
868
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
6.6
147
950
JJB10
NOMESCO Finland
Atypcal resection of liver
12.3
6.6
11
9
Z2221
NOMESCO Finland
Medical doctor
1.5
6.6
280
2087
M03BX02
ATC
tizanidine; oral
1.4
6.6
657
5685
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
6.5
219
1557
R20.2
ICD-10 Finland
Paraesthesia of skin
1.9
6.5
84
465
JN3GE
NOMESCO Finland
Intraoperative ultrasound examination of abdomen
70.3
6.4
7
*
J02AC01
ATC
fluconazole; systemic
1.4
6.4
443
3599
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
6.4
439
3562
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
4.1
6.4
17
42
R06AE07
ATC
cetirizine; oral
1.4
6.4
460
3763
IHA10
NOMESCO Finland
Structured mapping of problematic alcohol use
9.3
6.3
12
13
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
6.3
535
4494
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
3.0
6.3
26
87
D02
ICPC
Abdominal pain epigastric
1.9
6.2
74
398
XX9KE
NOMESCO Finland
Ultrasound examination with contrast
26.8
6.2
8
*
A02BA02
ATC
ranitidine; systemic
1.6
6.2
176
1204
D10
ICPC
Vomiting
2.0
6.2
70
370
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.4
6.2
328
2543
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
6.2
131
837
N03AX12
ATC
[U] gabapentin; oral
1.6
6.1
160
1074
D13.2
ICD-10 Finland
Benign neoplasm: Duodenum
7.7
6.1
13
17
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
6.1
308
2363
R06AX27
ATC
desloratadine; oral
1.4
6.1
318
2456
D39.10
ICD-10 Finland
Tumor of uncertain or unknown nature in the ovary without histology
2.9
6.1
27
94
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
6.0
112
690
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
6.0
180
1245
JJA20
NOMESCO Finland
Open biopsy of liver
10.1
6.0
11
11
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
10.1
6.0
11
11
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
2.3
6.0
43
190

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
349
841
5.67
143.34
2.7
4.5
2.70
24.56
ug/l
1.50
241
685
209
313
8.05
138.09
2.3
3.7
30.18
1370.36
u/ml
1.56
188
276
91
67
14.75
99.13
1.3
1.5
—
—
—
0
0
836
4919
4.18
88.39
7.6
6.3
10.79
10.81
umol/l
0.02
807
4692
119
166
7.94
82.38
2.3
3.6
106.57
1848.12
u/ml
0.63
110
157
318
1096
3.70
76.75
4.0
2.6
5.23
6.90
umol/l
2.51
286
956
694
4036
3.04
65.74
5.9
4.8
36.26
36.22
g/l
0.06
663
3814
261
874
3.63
64.73
2.7
2.3
0.23
0.22
g/l
1.24
253
825
462
2331
2.73
54.42
6.0
3.8
95.82
93.18
%
1.42
453
2271
968
7205
4.54
54.09
10.7
7.9
81.96
77.12
u/l
3.29
941
6857
648
3943
2.63
50.92
12.7
12.0
1.23
1.18
inr
0.25
524
3261
525
3016
2.45
44.78
3.3
2.6
55.76
61.77
u/l
1.44
488
2800
552
3381
2.30
38.93
4.3
3.2
33.62
30.56
u/l
0.71
534
3199
106
277
4.14
36.63
1.4
1.2
52.22
94.38
titre
—
9
32
207
892
2.64
31.13
3.3
2.5
32.29
39.31
u/l
1.16
171
748
739
5395
2.19
30.37
6.7
4.8
6.54
6.53
mmol/l
0.02
715
5053
396
2325
2.12
28.70
3.0
2.2
—
—
—
0
0
642
4524
2.04
27.88
3.1
2.7
—
—
estimate
—
0
0
172
731
2.61
26.32
8.5
7.7
7.97
9.13
mmol/l
1.20
165
705
476
3110
1.95
24.65
2.9
2.2
—
—
—
0
0
361
2192
1.98
22.76
1.7
1.5
2.16
2.30
g/l
1.01
244
1399
726
5551
1.95
22.56
9.3
9.5
4.38
4.03
e9/l
3.55
626
4881
279
1556
2.07
22.25
3.1
2.4
13.91
13.66
umol/l
0.26
268
1447
835
6736
2.08
21.82
4.8
3.2
65.24
42.85
u/l
8.77
809
6411
245
1316
2.12
21.51
3.1
2.4
22.87
23.11
%
0.11
235
1231
261
1442
2.07
21.23
3.1
2.4
2.47
2.36
g/l
1.85
246
1337
616
4543
1.84
20.51
9.8
6.8
1.21
1.21
mmol/l
0.07
557
3938
658
4986
1.83
19.69
6.6
6.2
0.57
0.56
e9/l
0.82
561
4346
391
2532
1.86
19.68
1.4
1.3
0.60
1.79
u/ml
3.85
106
715
658
4995
1.82
19.48
6.6
6.2
0.04
0.04
e9/l
0.61
562
4355
672
5162
1.81
18.82
6.8
6.5
0.19
0.19
e9/l
0.24
579
4566
662
5088
1.79
18.23
6.7
6.2
2.34
1.92
e9/l
0.65
579
4543
554
4049
1.76
18.13
8.5
6.1
1.21
1.21
mmol/l
0.03
522
3747
612
4626
1.75
17.57
6.8
6.1
57.61
57.02
%
0.64
587
4436
256
1498
1.93
17.27
1.6
1.3
630.51
505.35
titre
0.43
59
325
244
1413
1.94
16.95
3.6
2.9
2.73
2.89
e6/l
0.09
116
661
486
3475
1.73
16.74
5.0
3.8
38.43
92.92
e6/l
2.63
337
2364
155
764
2.20
16.64
8.0
7.7
1.30
1.28
mmol/l
0.06
155
750
424
2930
1.74
16.43
4.1
3.2
43.66
79.08
e6/l
0.63
309
2224
449
3157
1.73
16.31
6.7
6.2
—
—
—
0
0
612
4687
1.71
16.19
6.9
6.3
28.28
28.37
%
0.07
586
4479
234
1362
1.92
15.90
1.3
1.2
—
—
—
0
0
599
4574
1.70
15.90
7.0
6.4
8.30
8.60
%
1.93
570
4324
153
764
2.17
15.87
1.4
1.4
—
—
—
0
0
1024
9307
3.24
15.61
20.2
14.4
23.31
21.87
mg/l
0.74
925
7629
597
4571
1.69
15.54
6.9
6.2
2.70
2.80
%
0.58
568
4313
764
6258
1.77
15.50
5.3
4.4
321.67
1672.46
e6/l
—
9
81
255
1539
1.86
15.45
3.1
2.8
1.16
0.98
e6/l
0.18
124
785
130
614
2.27
15.44
2.1
1.8
1.18
1.48
g/l
1.36
124
569
595
4560
1.69
15.36
7.0
6.3
0.68
0.68
%
0.03
566
4291
239
1417
1.88
15.29
2.2
2.5
101.46
111.92
ug/g
0.28
192
1128
372
2518
1.73
15.26
3.9
3.1
0.29
0.40
e6/l
0.62
250
1824
141
696
2.18
15.03
10.4
9.2
—
—
—
0
0
1025
9348
3.20
14.99
22.3
16.2
139.72
139.65
mmol/l
0.41
1019
9176
224
1313
1.89
14.80
1.5
1.6
—
—
—
0
0
1025
9365
3.16
14.60
22.4
16.3
3.93
3.95
mmol/l
1.26
1018
9170
526
3941
1.66
14.50
2.6
2.1
—
—
—
0
0
175
953
2.00
14.33
9.0
8.1
0.45
0.85
mmol/l
0.75
151
789
177
969
1.99
14.28
9.0
8.1
7.42
7.41
ph
0.25
85
551
214
1260
1.87
13.87
1.4
1.3
—
—
—
0
0
133
678
2.10
12.99
4.2
3.7
91.31
81.55
ng/l
0.49
113
615
188
1106
1.85
12.09
1.4
1.3
—
—
—
0
0
196
1172
1.82
11.95
7.4
5.6
1.03
1.03
mmol/l
0.11
180
1086
84
367
2.40
11.90
2.6
1.8
22.36
20.67
s
0.54
74
329
150
836
1.92
11.37
1.4
1.2
—
—
—
0
0
338
2374
1.62
11.36
4.1
4.1
—
—
—
0
0
255
1674
1.69
11.14
3.6
3.7
1135.64
300.43
ng/l
0.45
177
1177
328
2300
1.61
11.04
2.2
1.7
0.93
1.08
mg/l
0.55
261
1758
339
2403
1.60
10.88
2.9
2.6
326.78
328.09
umol/l
0.09
311
2138
22
25
8.96
10.79
1.3
3.8
6.09
5.56
ug/l
0.12
22
25
440
3378
1.51
9.60
3.5
3.5
26.10
51.89
ng/l
0.74
260
2174
630
5226
1.50
9.31
4.2
3.7
0.03
0.31
estimate
0.46
104
1011
424
3250
1.50
9.22
3.1
3.4
2.36
2.35
mmol/l
0.74
388
2973
345
2538
1.53
9.09
2.7
2.2
2.68
2.75
mg/l
0.21
296
2201
624
5189
1.48
8.95
4.4
3.7
12.25
5.99
estimate
0.21
114
1072
516
4145
1.47
8.74
3.8
3.3
6.17
6.21
ph
0.37
277
2400
204
1340
1.65
8.69
2.2
2.0
—
—
—
0
0
66
302
2.26
8.45
1.5
1.4
268.58
293.34
ug/g
0.37
38
172
227
1543
1.60
8.39
4.2
3.2
0.82
0.82
mmol/l
0.02
209
1462
615
5138
1.46
8.34
4.3
3.6
0.00
0.00
estimate
0.50
109
1054
546
4463
1.46
8.29
3.2
2.5
72.69
76.39
nmol/l
2.76
504
4103
503
4054
1.45
8.19
2.3
2.0
99.63
97.14
pmol/l
0.55
289
2186
81
410
2.06
8.05
1.6
1.6
8.90
10.08
u/ml
0.18
18
101
605
5068
1.44
7.90
4.2
3.1
109.20
101.80
ug/l
0.46
580
4794
120
703
1.80
7.71
1.3
1.2
—
—
—
0
0
855
7688
1.55
7.63
5.3
4.6
14.56
14.57
pmol/l
0.06
799
7163
131
792
1.75
7.56
5.1
3.5
2.02
1.76
mmol/l
0.34
120
675
135
832
1.71
7.27
5.1
3.6
7.37
7.38
ph
1.20
76
473
354
2730
1.44
7.01
5.6
4.0
7.40
7.40
ph
0.08
246
1933
55
256
2.21
6.80
4.5
3.9
43.98
41.66
mg/l
0.07
48
220
274
2034
1.47
6.56
3.2
2.6
6.10
6.88
e6/l
0.38
244
1849
53
248
2.20
6.48
1.2
1.2
—
—
—
0
0
54
256
2.17
6.40
4.6
3.9
41.78
68.46
mg/l
0.58
48
221
359
2827
1.41
6.17
3.0
2.9
—
—
—
0
0
142
929
1.61
6.06
3.6
2.6
1.80
1.83
%
0.11
127
828
261
1949
1.45
6.00
1.7
1.7
—
—
—
0
0
244
1800
1.46
5.98
2.9
2.7
2.45
2.44
mmol/l
0.84
223
1632
49
230
2.18
5.97
3.4
3.6
1.29
2.47
ratio
1.67
29
132
121
766
1.65
5.89
1.4
1.3
341.16
208.55
u/ml
0.25
112
718
314
2432
1.41
5.89
2.9
3.1
1223.13
1056.97
ng/l
0.29
267
2054
1026
9800
2.09
5.86
16.4
11.5
29.50
25.26
u/l
9.71
1013
9575
950
8882
1.61
5.78
6.7
5.6
1.75
1.83
mu/l
1.70
898
8346
76
425
1.85
5.71
2.6
2.2
—
—
—
0
0
71
394
1.86
5.47
2.0
1.9
—
—
—
0
0
232
1729
1.44
5.33
4.3
2.8
536.28
527.57
mosm/kgh2o
0.23
201
1518
380
3079
1.36
5.33
3.7
3.4
7.78
7.65
mmol/l
0.17
340
2654
110
699
1.64
5.28
4.2
2.7
67.18
71.94
e9/l
0.94
79
507
36
158
2.32
5.16
1.0
1.0
0.07
0.08
u/ml
0.15
14
52
68
380
1.84
5.14
1.5
1.5
—
9.80
—
0
9
346
2775
1.36
5.14
2.2
2.1
178.16
194.44
u/l
0.18
330
2639
21
70
3.04
5.12
1.2
1.0
—
—
—
0
0
359
2906
1.35
5.00
6.2
5.9
—
—
—
0
0
269
2079
1.39
5.00
1.4
1.3
25.07
29.69
iu/ml
0.34
72
617
60
327
1.88
4.91
1.5
1.2
—
—
—
0
0
502
4280
1.33
4.88
11.8
10.8
0.00
0.00
e9/l
0.11
387
3528
128
863
1.55
4.81
1.4
1.5
—
—
—
0
0
158
1117
1.49
4.75
1.8
1.6
—
—
—
0
0
48
246
2.00
4.70
1.1
1.1
1.59
2.43
u/ml
0.46
24
130
326
2624
1.35
4.65
1.9
1.6
19.52
20.59
nmol/l
0.79
288
2257
36
167
2.20
4.57
1.1
1.1
—
—
—
0
0
36
167
2.20
4.57
1.1
1.1
—
—
—
0
0
106
693
1.59
4.55
3.3
3.7
4.46
4.57
pmol/l
0.54
97
617
43
215
2.04
4.52
1.1
1.1
1.44
4.41
u/ml
2.00
23
113
36
168
2.18
4.51
1.0
1.1
4.69
5.94
u/ml
0.16
16
71
16
49
3.30
4.48
1.9
2.0
1.84
5.99
nmol/l
—
10
38
78
474
1.70
4.46
2.1
2.1
0.07
0.01
estimate
0.43
27
156
62
356
1.79
4.33
1.9
2.0
1.47
1.47
g/l
0.00
50
313
343
2813
1.32
4.24
3.9
3.5
70.15
46.88
mg/l
0.73
238
1810
41
207
2.02
4.21
1.1
1.1
0.24
0.81
u/ml
2.20
16
87
347
2853
1.32
4.21
4.7
4.2
15.99
8.78
mg/mmol
1.04
243
1795
1009
9685
1.71
4.20
17.6
12.9
—
—
—
0
0
90
577
1.61
4.20
2.1
3.1
122.36
168.68
ng/l
0.85
83
526
174
1284
1.42
4.17
2.7
3.0
4.38
5.16
e9/l
0.78
148
1139
243
1909
1.35
3.99
1.4
1.3
16.61
12.10
u/ml
0.32
100
753
139
996
1.45
3.90
2.0
2.0
379.48
383.25
nmol/l
0.07
121
940
88
572
1.59
3.90
2.6
2.4
—
—
—
0
0
352
2927
1.30
3.87
1.5
1.6
—
—
—
0
0
126
890
1.47
3.81
1.9
2.0
0.03
0.03
estimate
0.01
36
187
104
707
1.52
3.78
2.6
2.9
67.27
67.40
g/l
0.07
93
659
36
182
2.01
3.72
1.0
1.1
1.10
2.77
u/ml
1.43
18
91
36
185
1.98
3.56
1.1
1.2
—
—
—
0
0
183
1399
1.37
3.56
1.7
1.7
1118.06
1203.27
nmol/l
0.66
144
1069
58
349
1.70
3.49
1.7
1.5
1.29
1.20
g/l
1.19
58
331
34
173
2.00
3.47
1.6
1.2
2.13
4.88
u/ml
1.10
16
69
83
548
1.56
3.46
1.1
1.1
—
162.00
—
0
13
917
8692
1.38
3.40
7.2
5.9
39.23
38.58
mmol/mol
1.39
878
8224
26
120
2.20
3.40
2.9
2.2
—
—
—
0
0
69
440
1.61
3.34
2.7
2.7
0.57
0.62
%
1.09
69
440
58
354
1.67
3.33
1.3
1.3
—
—
—
0
0
47
271
1.77
3.30
9.0
3.8
1.18
1.33
mmol/l
0.85
47
264
48
791
0.59
3.27
5.6
3.7
—
—
—
0
0
95
655
1.49
3.26
2.0
2.3
7.39
6.73
ug/l
0.12
85
580
50
296
1.72
3.21
2.3
2.0
9.97
10.34
g/l
0.38
43
276
108
770
1.45
3.14
1.5
1.3
26.57
26.74
iu/l
0.02
88
669
29
145
2.03
3.12
1.3
1.2
—
—
—
0
0
38
209
1.85
3.12
1.1
1.1
0.29
1.38
u/ml
2.01
17
109
37
203
1.85
3.06
1.7
1.4
—
—
—
0
0
80
542
1.51
3.00
1.3
1.2
—
—
—
0
0
117
854
1.42
3.00
5.9
3.7
7.36
7.35
ph
0.40
87
624
14
51
2.77
2.99
1.4
2.5
3121.43
635.00
u/ml
0.53
14
51
34
183
1.89
2.99
1.4
1.4
184.18
160.55
au/ml
0.74
11
52
17
69
2.49
2.97
2.4
2.9
735.49
1268.70
mg
0.74
17
69
8
17
4.73
2.92
1.3
1.1
0.06
0.02
u/ml
—
8
17
169
1324
1.33
2.80
1.4
1.5
—
—
—
0
0
47
286
1.67
2.77
3.0
2.7
—
—
—
0
0
272
2280
1.26
2.67
4.3
3.7
1.02
1.67
kg/l
0.50
191
1542
68
457
1.52
2.67
1.5
1.9
8.60
8.12
iu/ml
0.05
13
107
39
228
1.74
2.66
2.8
3.2
0.84
2.27
index
1.24
19
115
34
192
1.80
2.61
4.3
2.7
8.06
8.01
pmol/l
0.02
34
192
918
8780
1.32
2.58
4.8
4.1
1.39
1.25
mmol/l
6.82
866
8177
59
388
1.55
2.56
2.9
4.9
1.66
1.53
%
0.46
59
368
5
7
7.17
2.55
10.2
4.7
5.84
6.51
mmol/l
—
5
7
931
8928
1.33
2.51
5.5
4.8
5.92
5.83
mmol/l
1.49
884
8312
48
302
1.62
2.51
1.1
1.1
1.20
5.68
eliau/ml
—
5
45
154
1213
1.31
2.46
1.5
1.4
—
—
—
0
0
50
321
1.58
2.42
1.3
1.2
1.71
2.62
u/ml
—
8
31
50
322
1.58
2.39
1.3
1.2
4.55
8.31
u/ml
0.44
11
50
441
3934
1.21
2.34
4.3
3.5
0.00
0.03
estimate
3.18
84
881
10
34
2.96
2.28
1.0
1.3
—
—
—
0
0
58
392
1.51
2.26
3.0
3.1
—
—
—
0
0
14
60
2.35
2.22
5.5
7.5
0.67
331.31
ug/l
—
9
36
1037
10160
1.63
2.19
31.7
22.1
268.25
257.33
e9/l
5.04
1021
10000
321
2793
1.21
2.18
4.6
3.8
0.00
0.01
estimate
1.34
103
1004
15
67
2.26
2.18
1.1
1.0
1.30
0.29
u/ml
—
7
26
8
24
3.35
2.18
2.6
3.9
—
—
—
0
0
66
463
1.45
2.15
1.7
1.6
0.29
0.34
mg/l
0.39
37
209
1037
10163
1.62
2.14
31.6
22.0
90.52
90.83
fl
1.54
1032
10079
1037
10165
1.62
2.11
31.7
22.1
4.49
4.49
e12/l
0.07
1022
9984
1037
10165
1.62
2.11
31.6
22.0
30.05
30.23
pg
2.89
1032
10080
1037
10166
1.61
2.10
31.7
22.2
7.08
6.68
e9/l
7.19
1023
9976
17
82
2.09
2.07
2.3
2.5
—
—
—
0
0
94
707
1.36
2.07
2.3
2.4
12.04
22.34
au/ml
—
7
81
9
31
2.92
2.07
3.4
2.6
0.61
0.61
mmol/l
—
9
31
80
586
1.39
2.07
3.6
2.3
12.50
12.09
nmol/l
0.15
66
528
24
132
1.84
2.05
1.2
1.3
0.50
0.59
nmol/l
1.32
24
125
6
15
4.02
2.04
1.8
1.9
—
—
—
0
0
11
44
2.52
2.01
1.5
1.7
—
4617.14
—
0
7
14
63
2.24
2.01
1.1
1.0
0.41
0.42
u/ml
—
6
15
19
97
1.98
2.01
1.4
1.4
—
—
—
0
0
11
45
2.46
1.93
42.8
28.6
6.17
7.15
ug/l
0.82
11
38
47
316
1.51
1.91
3.6
3.6
361.85
309.68
mg/l
0.17
26
133
53
366
1.47
1.90
5.2
3.4
25.26
25.25
mmol/l
0.01
53
350
49
333
1.49
1.90
2.0
1.9
3.58
2.39
ug/l
0.17
41
300
76
562
1.38
1.88
1.8
2.1
3889.22
6341.64
u/l
0.44
25
231
448
4061
1.18
1.88
2.0
1.9
1.45
1.34
mmol/l
1.97
393
3515
8
28
2.87
1.86
1.0
1.1
—
—
—
0
0
47
318
1.50
1.86
1.6
2.1
2.38
4.28
iu/l
2.12
18
134
18
93
1.95
1.85
1.3
1.1
—
—
—
0
0
955
9258
1.29
1.84
5.7
4.9
4.66
4.71
mmol/l
0.99
917
8746
21
115
1.84
1.83
1.0
1.3
0.17
0.35
nmol/l
0.51
14
80
33
207
1.61
1.81
1.3
1.3
211.00
256.82
u/ml
0.59
16
128
46
312
1.50
1.81
1.2
1.2
—
—
—
0
0
27
161
1.69
1.79
1.5
1.9
—
9.40
—
0
5
9
36
2.51
1.74
1.2
1.6
73.33
74.92
nmol/24h
—
9
36
951
9227
1.27
1.73
5.6
4.8
1.45
1.50
mmol/l
3.01
900
8669
8
30
2.68
1.72
1.8
1.2
36.38
27.97
s
—
8
30
7
24
2.93
1.72
1.1
1.1
—
—
—
0
0
57
408
1.42
1.72
1.3
1.2
—
—
—
0
0
18
96
1.89
1.71
1.1
1.1
—
—
—
0
0
17
89
1.92
1.70
1.1
1.1
—
—
—
0
0
30
187
1.62
1.70
1.3
1.4
3.17
2.59
ug/l
0.35
24
169
16
82
1.97
1.70
2.6
3.5
—
—
—
0
0
76
574
1.35
1.67
3.2
3.1
7.42
7.42
ph
0.03
60
484
7
25
2.81
1.65
1.0
1.0
—
—
—
0
0
12
56
2.16
1.61
1.1
1.3
—
—
—
0
0
8
32
2.51
1.60
1.6
1.5
—
—
—
0
0
33
215
1.55
1.58
2.9
3.0
1.88
1.56
mmol/l
0.92
33
210
77
590
1.33
1.56
3.3
3.1
5.12
5.12
kpa
0.00
71
572
23
138
1.68
1.52
1.2
1.3
—
0.86
nmol/l
—
0
5
9
37
2.44
1.48
1.2
1.3
—
—
—
0
0
6
22
2.74
1.43
1.7
1.3
5.67
9.01
mmol/l
—
6
22
35
237
1.49
1.43
1.5
1.5
526.33
612.34
e6/l
0.05
30
189
268
2378
1.17
1.41
3.8
4.6
—
—
—
0
0
18
103
1.76
1.41
3.3
2.9
2.35
1.30
g/24h
0.49
11
63
959
9354
1.24
1.37
6.4
5.4
2.70
2.77
mmol/l
1.87
912
8810
72
559
1.31
1.35
1.1
1.1
—
—
—
0
0
17
97
1.76
1.35
1.6
1.5
—
—
—
0
0
124
1030
1.23
1.35
1.5
1.4
—
—
—
0
0
322
2910
1.15
1.33
3.9
3.1
0.00
0.10
estimate
0.95
87
861
27
176
1.55
1.32
2.1
1.8
—
—
—
0
0
139
1172
1.21
1.31
3.5
3.2
0.78
0.72
ug/l
0.36
101
749
34
234
1.47
1.30
1.4
1.5
62.76
12.20
e6/l
0.68
29
181
6
24
2.51
1.30
1.0
1.0
—
—
—
0
0
38
268
1.43
1.29
1.2
1.2
—
—
—
0
0
5
18
2.79
1.28
1.8
3.7
—
—
—
0
0
56
426
1.33
1.23
2.2
1.8
—
—
—
0
0
18
108
1.68
1.22
4.5
5.3
10.31
45.65
u/ml
—
8
35
5
19
2.64
1.21
1.4
1.1
—
—
—
0
0
8
38
2.11
1.18
2.1
1.8
—
—
—
0
0
20
125
1.61
1.18
1.5
1.3
—
—
—
0
0
5
20
2.51
1.15
1.8
2.3
—
—
—
0
0
28
191
1.48
1.14
2.8
2.4
62.15
115.91
ug/min
0.59
17
121
15
88
1.71
1.11
1.5
1.4
1.97
1.43
nmol/l
0.66
15
80
20
128
1.57
1.09
1.5
1.6
—
—
—
0
0
61
480
1.29
1.08
1.3
1.6
316.13
313.95
mu/l
0.02
53
439
100
834
1.22
1.08
4.7
5.0
1.54
0.17
%
0.42
24
194
17
105
1.63
1.06
1.9
1.6
—
—
—
0
0
25
170
1.48
1.05
3.1
7.3
11.44
11.17
mmol/l
0.15
25
155
25
171
1.47
1.03
3.1
7.2
103.16
105.23
mmol/l
1.19
25
156
7
35
2.01
1.00
2.4
2.2
42.16
41.51
g/l
—
7
35
98
825
1.21
0.98
1.3
1.2
167.55
142.28
u/ml
0.17
31
342
14
84
1.68
0.98
1.3
1.2
—
—
—
0
0
42
319
1.33
0.97
1.2
1.3
11.95
10.29
u/l
0.30
27
257
31
224
1.40
0.97
1.6
1.7
—
—
—
0
0
97
817
1.21
0.97
4.6
4.7
0.04
0.12
%
0.96
25
209
97
819
1.20
0.95
4.3
4.5
0.42
0.66
%
0.88
32
231
7
37
1.90
0.94
2.7
1.8
56.20
51.31
ug/l
—
7
37
13
78
1.67
0.91
1.0
1.2
—
—
—
0
0
32
236
1.37
0.90
1.1
1.3
3.95
3.65
mmol/l
0.88
32
221
12
71
1.70
0.89
1.0
2.0
46.40
40.29
%
0.69
12
71
18
119
1.52
0.88
1.4
1.3
—
—
—
0
0
6
31
1.94
0.84
2.8
3.3
—
—
—
0
0
8
45
1.78
0.84
1.6
1.3
101.38
170.33
mmol/24h
—
8
45
21
146
1.45
0.83
2.0
1.5
250.12
334.10
mu/l
1.75
16
121
216
1967
1.12
0.80
6.1
5.4
2.53
2.35
ug/l
0.21
205
1768
249
2288
1.11
0.79
2.0
2.0
—
—
—
0
0
37
287
1.30
0.78
1.2
1.1
—
—
—
0
0
29
217
1.35
0.77
1.5
1.3
27.72
26.09
u/l
0.10
22
181
31
235
1.33
0.76
1.2
1.5
0.23
0.37
nmol/l
1.64
20
188
15
99
1.52
0.76
1.5
1.3
—
—
—
0
0
23
169
1.37
0.70
3.3
3.2
8.23
7.58
mmol/l
0.36
23
164
53
438
1.22
0.68
1.0
1.1
—
—
—
0
0
9
59
1.53
0.68
1.0
1.1
1780.78
1595.44
miu/ml
—
9
59
11
168
0.65
0.68
3.2
3.5
4.19
4.12
e9/l
0.03
11
168
53
439
1.22
0.67
1.2
1.4
234.81
236.87
miu/ml
0.02
28
222
21
153
1.38
0.67
1.1
1.1
—
78.61
—
0
31
380
4011
0.92
0.67
3.0
2.9
—
—
—
0
0
5
28
1.79
0.66
1.0
1.4
10.38
14.21
g/l
—
5
21
12
78
1.54
0.65
1.0
1.2
—
—
—
0
0
60
707
0.84
0.64
1.5
1.6
1126.71
1001.95
mu/l
0.34
46
584
24
181
1.33
0.63
1.0
1.1
1.40
2.41
eliau/ml
0.76
11
83
11
71
1.55
0.62
1.4
1.6
11.23
11.82
umol/l
0.18
11
64
5
30
1.67
0.61
1.6
1.4
—
—
—
0
0
15
105
1.43
0.60
1.5
1.6
33.89
26.08
ng/l
0.20
15
105
12
80
1.51
0.60
1.9
1.6
—
—
—
0
0
8
52
1.54
0.59
1.5
3.3
17.01
16.79
%
—
8
52
97
859
1.14
0.58
4.6
4.6
0.72
1.04
%
0.30
25
253
8
53
1.51
0.58
1.4
3.2
9.17
8.77
mmol/l
—
8
53
50
421
1.20
0.56
4.2
3.1
1.02
1.02
ratio
0.29
44
395
17
124
1.38
0.56
1.4
1.2
—
—
—
0
0
96
1076
0.88
0.55
1.4
1.3
—
—
—
0
0
44
367
1.21
0.55
1.5
1.6
—
—
—
0
0
6
38
1.58
0.54
1.5
1.6
0.48
0.45
e9/l
—
6
38
14
99
1.42
0.54
1.1
1.1
—
—
—
0
0
6
39
1.54
0.53
1.3
2.1
—
—
—
0
0
18
136
1.33
0.49
1.5
1.5
—
—
—
0
0
18
136
1.33
0.49
1.5
1.5
—
—
—
0
0
18
136
1.33
0.49
1.5
1.5
—
—
—
0
0
18
136
1.33
0.49
1.5
1.5
—
—
—
0
0
74
657
1.14
0.46
1.7
1.8
—
—
—
0
0
17
220
0.77
0.45
2.8
3.3
56.53
57.20
%
0.08
17
220
15
112
1.34
0.44
1.6
1.7
—
—
—
0
0
26
211
1.24
0.44
1.5
1.5
—
—
—
0
0
20
157
1.28
0.43
1.2
1.2
—
—
—
0
0
11
78
1.41
0.43
1.1
1.0
—
—
—
0
0
78
700
1.12
0.42
5.5
3.5
1.23
1.23
mmol/l
0.30
71
599
0
19
0.00
0.39
0.0
1.1
—
0.02
—
0
19
5
37
1.35
0.37
1.0
1.1
—
—
—
0
0
5
37
1.35
0.37
1.0
1.1
—
—
—
0
0
5
37
1.35
0.37
1.0
1.1
—
—
—
0
0
14
108
1.30
0.35
1.4
1.1
—
—
—
0
0
6
43
1.40
0.35
2.7
4.1
1.00
0.84
index
—
6
43
200
1901
1.06
0.32
1.6
1.7
53488781.47
36667097.83
pmol/l
0.12
172
1620
6
47
1.28
0.32
2.7
2.0
—
—
—
0
0
52
465
1.12
0.32
1.5
1.7
—
—
—
0
0
28
239
1.18
0.31
1.1
1.1
—
—
—
0
0
7
52
1.35
0.31
2.0
1.4
144.14
144.73
nmol/l
—
7
52
7
52
1.35
0.31
4.9
1.7
77.29
107.11
ng/l
—
7
52
10
75
1.34
0.30
1.4
1.1
—
—
—
0
0
15
120
1.25
0.30
1.0
1.1
—
—
—
0
0
37
326
1.14
0.29
2.1
2.0
—
—
—
0
0
21
176
1.20
0.29
1.6
1.2
—
—
—
0
0
13
103
1.27
0.28
1.5
2.3
31.46
32.47
pg
0.32
13
103
12
94
1.28
0.28
1.3
1.1
17.77
17.17
u/ml
—
6
46
41
458
0.89
0.27
1.2
1.1
1.53
1.58
g/l
0.86
41
458
48
433
1.11
0.27
1.5
1.7
—
—
—
0
0
84
780
1.08
0.27
2.0
2.3
6.23
6.10
ph
0.64
47
515
51
464
1.10
0.25
1.5
1.7
—
—
—
0
0
16
191
0.84
0.24
3.8
2.8
—
—
—
0
0
22
189
1.17
0.24
6.9
4.3
—
—
—
0
0
5
38
1.32
0.23
1.8
2.8
—
—
—
0
0
128
1217
1.06
0.22
1.9
1.8
—
—
—
0
0
51
468
1.09
0.22
1.5
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
39.70
—
0
10
12
98
1.23
0.21
4.5
2.2
—
—
—
0
0
5
43
1.16
0.21
1.0
1.3
95.08
147.31
pmol/l
—
5
43
11
89
1.24
0.21
1.3
1.1
92.64
109.26
pmol/l
0.75
11
89
0
14
0.00
0.20
0.0
6.7
—
4.97
—
0
14
23
202
1.14
0.20
1.8
1.8
—
—
—
0
0
50
462
1.09
0.19
1.5
1.7
—
—
—
0
0
6
51
1.18
0.19
1.3
1.2
173.00
480.57
u/l
—
6
44
99
940
1.06
0.19
1.8
1.7
3.55
3.46
mmol/l
0.32
67
657
27
243
1.11
0.17
1.6
1.5
5808.36
12912.85
e6/l
1.21
14
172
10
82
1.22
0.17
1.3
1.4
8.37
6.37
ug/l
—
10
69
5
68
0.73
0.17
1.6
2.1
8.80
2.61
u/field
—
5
41
8
72
1.11
0.16
13.0
14.6
0.62
0.65
mmol/l
—
8
67
9
79
1.14
0.15
1.0
1.5
1.25
1.14
promille
—
9
63
9
80
1.13
0.15
1.2
1.2
—
—
—
0
0
9
81
1.11
0.15
2.1
1.4
—
—
—
0
0
16
180
0.89
0.13
3.4
3.8
39.01
24.43
mg/l
0.38
11
120
20
221
0.90
0.13
2.8
2.2
125.18
129.78
g/l
0.43
11
181
126
1221
1.04
0.12
2.0
1.9
3.47
3.36
ratio
0.44
94
932
5
44
1.14
0.10
1.8
2.6
—
—
—
0
0
5
47
1.06
0.09
3.0
1.6
—
—
—
0
0
7
67
1.05
0.08
2.3
1.3
—
—
—
0
0
9
85
1.06
0.07
3.7
2.7
—
—
—
0
0
8
90
0.89
0.06
3.4
2.6
4.40
4.02
mmol/l
—
8
90
8
90
0.89
0.06
3.4
2.6
107.63
105.89
mmol/l
—
8
90
30
315
0.95
0.06
1.4
1.5
—
—
—
0
0
40
415
0.96
0.05
1.4
1.5
67.37
60.66
ug/l
0.41
32
347
31
322
0.96
0.04
1.5
1.6
—
—
—
0
0
10
92
1.09
0.03
1.5
1.3
6.29
6.12
mmol/l
—
10
85
30
310
0.97
0.03
1.4
1.5
1.19
1.29
mm
0.50
22
219
13
122
1.07
0.02
2.6
2.6
—
—
—
0
0
27
278
0.97
0.02
4.6
9.2
—
—
—
0
0
136
1353
1.01
0.00
1.6
1.8
—
—
—
0
0
11
114
0.96
0.00
3.2
2.4
—
—
—
0
0
23
226
1.02
0.00
1.2
1.1
—
—
—
0
0
23
226
1.02
0.00
1.2
1.1
—
—
—
0
0
29
288
1.01
0.00
1.4
1.3
—
—
—
0
0
16
157
1.02
0.00
1.6
1.4
57.09
63.75
mmol/l
0.22
11
136
8
89
0.90
-0.00
3.4
2.6
1.20
1.20
mmol/l
—
8
89
0
8
0.00
-0.00
0.0
1.1
—
0.03
—
0
8
0
6
0.00
-0.00
0.0
1.2
—
382.67
—
0
6
7
75
0.93
-0.00
1.3
1.3
67.00
73.89
umol/l
—
7
75
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
365.13
—
0
8
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
0.44
—
0
5

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_LIVE_BILE and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_LIVE_BILE 1.65 [1.41, 1.93] < 0.001
Birth year 0.994 [0.99, 1.0] 0.164

During the follow-up period (1.1.1998 — 31.12.2019), 315 out of 2402 females with CD2_BENIGN_LIVE_BILE died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_LIVE_BILE 1.985 [1.62, 2.42] < 0.001
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 310 out of 1102 males with CD2_BENIGN_LIVE_BILE died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_LIVE_BILE.

N-year risk Females Males
1 0.15% 0.324%
5 0.89% 2.124%
10 2.35% 5.521%
15 4.438% 10.241%
20 7.635% 16.824%

Relationships between endpoints

Index endpoint: CD2_BENIGN_LIVE_BILE – Benign neoplasm: Liver/bile ducts

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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