No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
128 |
4. Check minimum number of eventsNone |
128 |
5. Include endpointsNone |
128 |
6. Filter based on genotype QC (FinnGen only) |
109 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF13
Similar endpoints
↥List of similar endpoints to
Absence of one kidney, including avohilmo
based on the number of shared cases.
Similar with more cases:
- Renal agenesis and other reduction defects of kidney, including avohilmo
- Congenital malformations of the urinary system, including avohilmo
- Vertebral, anorectal, cardiavascular, thracheoesophagial, renal and limb anomaly, including avohilmo
- Congenital malformations, deformations and chromosomal abnormalities, including avohilmo
- Any operation in hilmo
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 109 | 54 | 55 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.03 |
| Median age at first event (years) | 50.96 | 40.43 | 61.30 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 119
- Matched controls
- 1190
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q60.0
ICD-10 Finland
Renal agenesis, unilateral
+∞
171.8
119
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
15.6
38.5
39
36
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
28.3
18.7
25
11
A11CC03
ATC
alfacalcidol; systemic
33.0
18.7
24
9
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
9.1
17.7
24
32
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
26.2
13.4
18
8
205
Kela drug reimbursment
Chronic hypertension
4.4
13.2
47
155
KA1AE
NOMESCO Finland
Kidney ultrasound examination
36.6
12.9
16
5
Z94.0
ICD-10 Finland
Kidney transplant status
36.6
12.9
16
5
A12AA04
ATC
calcium carbonate; oral
28.0
12.9
17
7
N18.8
ICD-10 Finland
Other chronic renal failure
15.9
11.9
19
14
127
Kela drug reimbursment
Transplant complication
22.8
11.5
16
8
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
66.1
10.8
12
*
N19
ICD-10 Finland
Unspecified kidney failure
10.4
10.8
21
24
UKC02
NOMESCO Finland
Cystoscopy
4.6
10.5
30
82
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
33.0
9.6
12
*
L04AD02
ATC
tacrolimus; systemic
40.0
9.2
11
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
20.6
9.2
13
7
137
Kela drug reimbursment
Uraemia requiring dialysis
26.4
9.1
12
5
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.0
8.9
30
92
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
54.1
8.8
10
*
TK800
NOMESCO Finland
Hemodialysis
18.0
8.8
13
8
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
30.0
8.6
11
*
Q60.3
ICD-10 Finland
Renal hypoplasia, unilateral
+∞
8.4
8
*
75301
ICD-8 Finland
Congenital anomalies of urinary system, Agenesis renis unilateralis
+∞
8.4
8
*
7530A
ICD-9 Finland
Congenital anomalies of urinary system, Renal agenesis and dysgenesis[AGENESIA RENIS]
+∞
8.4
8
*
L04AA06
ATC
mycophenolic acid; systemic
16.0
8.4
13
9
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.6
8.2
34
120
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
36.1
8.2
10
*
ZXE20
NOMESCO Finland
More than three and less than five hours
3.9
7.8
26
79
N18.0
ICD-10 Finland
End-stage renal disease
85.2
7.5
8
*
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
+∞
7.4
7
*
B05DA
ATC
Isotonic solutions
32.2
7.3
9
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.5
7.0
28
96
Z49.0
ICD-10 Finland
Preparatory care for dialysis
42.5
6.8
8
*
Z49.1
ICD-10 Finland
Extracorporeal dialysis
42.5
6.8
8
*
TK820
NOMESCO Finland
Peritoneal dialysis
42.5
6.8
8
*
M04AA01
ATC
allopurinol; systemic
3.5
6.5
25
83
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
28.3
6.3
8
*
KBV00
NOMESCO Finland
Insertion of stent into ureter
+∞
6.3
6
*
U14
ICPC
Kidney symptom/complaint
8.8
6.0
12
15
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
31
64
6.20
15.27
8.8
15.0
1.59
1.27
mg/l
1.36
31
58
70
295
4.33
14.16
9.0
4.1
25.54
12.01
mg/mmol
1.32
53
188
77
409
3.50
9.90
10.4
3.6
—
—
—
0
0
32
107
3.72
8.41
9.3
10.1
23.14
23.50
mmol/l
0.33
32
107
86
525
3.30
8.11
21.9
11.2
1.23
1.21
mmol/l
0.78
77
463
78
464
2.98
7.44
10.5
6.3
35.44
35.93
g/l
0.31
71
439
36
140
3.25
7.41
10.9
8.9
5.98
5.71
kpa
1.23
36
140
33
125
3.27
7.06
8.1
9.4
4.85
4.64
kpa
0.30
33
125
79
484
2.88
6.95
23.4
10.7
1.23
1.22
mmol/l
1.51
73
455
35
139
3.15
6.91
11.1
8.8
0.41
0.98
mmol/l
0.50
35
118
16
40
4.47
6.12
2.0
1.5
—
—
—
0
0
16
40
4.47
6.12
1.4
1.5
220.80
139.92
u/ml
—
10
17
88
598
2.81
5.88
7.3
3.9
0.00
12.03
estimate
0.50
18
135
16
42
4.25
5.75
1.4
1.5
—
—
—
0
0
88
603
2.76
5.70
7.3
4.0
0.00
0.00
estimate
-0.00
18
125
86
593
2.62
5.32
7.1
3.9
0.00
0.00
estimate
-0.00
18
131
74
483
2.41
5.06
4.8
2.8
75.95
74.14
nmol/l
0.24
68
433
39
193
2.52
4.93
6.3
3.7
3.15
1.85
e6/l
0.38
26
104
26
111
2.72
4.38
7.7
8.1
0.37
1.18
mmol/l
0.66
19
84
55
338
2.17
4.08
9.5
3.4
0.33
0.24
e6/l
0.22
48
251
38
209
2.20
3.66
6.4
3.4
0.48
0.85
e6/l
0.62
26
119
65
445
2.02
3.46
6.4
3.8
0.00
0.01
estimate
0.50
14
108
13
39
3.61
3.35
2.7
1.2
—
—
—
0
0
7
11
6.68
3.23
7.1
5.4
1578.43
854.18
mg
—
7
11
15
56
2.92
3.20
8.9
4.5
52.16
52.08
%
0.00
15
56
52
337
1.96
3.16
7.6
4.0
0.00
0.00
estimate
-0.00
15
125
62
431
1.92
3.03
2.5
2.0
95.26
95.85
pmol/l
0.03
30
231
16
65
2.69
2.93
8.7
10.2
0.64
0.62
%
0.10
16
65
56
380
1.89
2.92
5.4
3.5
2.41
2.36
mmol/l
2.00
51
343
50
329
1.90
2.85
5.8
3.1
0.00
0.00
estimate
-0.00
13
107
11
34
3.46
2.81
2.0
2.9
2.40
2.00
index
—
5
20
12
40
3.22
2.79
6.2
6.0
22.99
24.32
mmol/l
1.03
12
40
28
151
2.12
2.77
8.9
11.8
103.96
104.16
mmol/l
0.11
28
151
8
19
4.43
2.73
14.8
3.4
13.89
9.56
pmol/l
—
8
19
9
25
3.81
2.63
1.0
1.2
—
—
—
0
0
41
261
1.87
2.54
7.0
4.0
1.02
1.02
kg/l
0.92
34
179
18
84
2.35
2.50
3.6
2.7
44.29
67.74
ml/min/173m2
—
7
34
10
33
3.21
2.42
3.0
1.7
—
—
—
0
0
81
640
1.83
2.42
10.4
7.8
6.52
6.46
mmol/l
0.09
76
606
7
17
4.30
2.40
1.6
1.2
—
—
—
0
0
29
170
1.93
2.27
2.1
1.7
1286.52
1282.90
nmol/l
0.01
23
127
43
287
1.78
2.25
2.6
2.5
2.65
2.73
mg/l
0.11
36
247
21
112
2.06
2.13
6.2
3.5
—
—
—
0
0
54
390
1.70
2.12
3.6
4.2
45.85
35.92
ng/l
0.25
41
279
32
199
1.83
2.09
2.9
1.9
—
—
—
0
0
11
44
2.65
2.08
10.7
3.9
25.51
24.23
mmol/l
0.78
11
44
7
21
3.47
2.00
1.0
1.6
—
—
—
0
0
7
21
3.47
2.00
1.0
1.6
—
—
—
0
0
5
11
4.69
1.96
1.2
1.3
—
—
—
0
0
24
141
1.88
1.86
3.4
1.8
—
—
—
0
0
69
544
1.64
1.86
7.0
3.2
141.14
94.52
ug/l
1.41
64
507
38
259
1.69
1.80
2.8
3.2
—
—
—
0
0
102
898
1.95
1.78
5.8
4.3
1.34
1.26
mmol/l
0.38
93
833
20
112
1.94
1.78
6.5
15.0
0.44
0.90
mmol/l
0.12
14
92
62
486
1.58
1.64
4.4
3.3
—
—
estimate
—
0
0
7
26
2.79
1.60
1.3
2.7
0.00
0.00
g/l
—
7
26
7
26
2.79
1.60
4.3
2.7
14.99
16.73
%
—
7
26
24
148
1.78
1.60
3.4
1.7
—
—
—
0
0
80
669
1.60
1.57
8.8
12.3
4.36
4.12
e9/l
0.37
70
586
8
33
2.52
1.57
2.0
2.7
—
—
—
0
0
6
21
2.95
1.52
1.5
1.3
—
—
—
0
0
9
40
2.35
1.43
1.3
1.4
—
—
—
0
0
104
945
1.80
1.30
6.8
4.9
1.48
1.43
mmol/l
0.69
96
876
105
958
1.82
1.28
7.0
5.7
2.43
2.66
mmol/l
1.96
96
889
40
298
1.52
1.27
2.4
1.6
21.78
21.99
nmol/l
0.02
33
252
104
947
1.78
1.26
6.9
5.0
4.37
4.53
mmol/l
0.95
96
883
8
39
2.13
1.18
1.4
1.7
—
—
—
0
0
7
31
2.33
1.12
1.3
1.5
—
—
—
0
0
5
21
2.44
1.10
1.0
1.4
—
8.70
—
0
10
9
46
2.03
1.06
1.3
1.8
—
—
—
0
0
111
1049
1.86
1.01
31.9
17.1
24.97
23.23
mg/l
0.22
96
868
9
51
1.83
0.97
1.3
1.8
—
—
—
0
0
6
30
2.05
0.88
1.3
1.7
—
—
—
0
0
6
31
1.98
0.85
1.5
1.3
—
—
—
0
0
6
32
1.92
0.83
1.0
1.8
—
—
—
0
0
33
256
1.40
0.83
1.5
1.7
—
—
—
0
0
11
66
1.73
0.82
4.9
1.6
—
—
—
0
0
5
24
2.13
0.75
1.0
1.5
—
—
—
0
0
5
24
2.13
0.75
1.0
1.4
—
5.64
—
0
11
5
24
2.13
0.75
1.4
1.8
—
—
—
0
0
5
25
2.04
0.73
1.4
1.5
—
—
—
0
0
16
114
1.47
0.63
10.1
8.8
—
—
—
0
0
5
30
1.70
0.62
4.8
2.3
112.20
135.00
g/l
—
5
22
9
59
1.57
0.56
1.6
1.3
—
—
—
0
0
6
39
1.57
0.54
2.5
2.6
—
—
—
0
0
9
63
1.46
0.54
1.6
2.8
296.56
228.65
ng/l
—
9
57
7
47
1.52
0.48
1.3
2.2
—
—
—
0
0
5
82
0.59
0.47
1.4
1.0
—
—
—
0
0
5
31
1.64
0.43
1.2
1.2
—
—
—
0
0
5
32
1.59
0.43
1.2
1.2
—
—
—
0
0
11
79
1.43
0.42
2.4
1.9
—
—
—
0
0
0
19
0.00
0.39
0.0
1.9
—
3.44
—
0
19
26
305
0.81
0.37
1.3
1.5
0.60
1.61
u/ml
—
7
76
100
959
1.27
0.37
5.1
5.1
2.08
1.91
mu/l
0.43
92
875
6
43
1.42
0.35
1.7
1.5
—
—
—
0
0
14
174
0.78
0.32
1.7
2.3
—
—
—
0
0
90
938
0.83
0.31
7.8
4.8
5.88
5.81
mmol/l
0.24
82
847
5
40
1.26
0.22
1.0
1.9
191.20
219.20
pmol/l
—
5
35
14
117
1.22
0.21
5.9
5.1
34.78
31.68
%
—
9
78
0
11
0.00
0.21
0.0
1.6
—
9.37
—
0
11
0
10
0.00
0.21
0.0
1.9
—
47.50
—
0
10
0
10
0.00
0.21
0.0
1.9
—
13.17
—
0
10
24
213
1.16
0.20
2.5
2.8
2.52
2.45
mmol/l
1.64
19
188
7
61
1.16
0.18
1.1
1.6
24.34
20.53
iu/l
—
7
45
33
304
1.12
0.17
3.6
3.7
4898.37
1474.10
ng/l
0.84
28
246
94
915
1.13
0.16
9.4
5.9
39.21
38.61
mmol/mol
0.30
88
857
16
179
0.88
0.13
1.5
1.3
62.90
29.03
iu/ml
—
6
51
10
116
0.85
0.12
2.9
2.5
13.35
12.80
nmol/l
—
10
108
17
188
0.89
0.12
1.9
2.4
—
—
—
0
0
13
146
0.88
0.11
1.3
1.4
—
—
—
0
0
5
44
1.14
0.10
1.4
1.8
38.80
40.99
u/l
—
5
38
5
44
1.14
0.10
1.4
1.9
—
—
—
0
0
28
264
1.08
0.08
1.8
2.7
1.21
1.34
mg/l
0.11
21
217
19
204
0.92
0.07
2.3
3.0
0.73
0.80
ug/l
0.17
12
135
72
736
0.94
0.07
4.1
3.5
—
—
—
0
0
8
93
0.85
0.07
1.0
1.5
—
—
—
0
0
81
800
1.04
0.03
4.3
4.2
14.75
14.76
pmol/l
0.01
76
721
21
203
1.04
0.01
3.2
3.2
94.21
354.91
ng/l
0.84
14
147
26
267
0.97
0.01
3.2
4.8
27.58
21.59
%
1.09
14
140
12
114
1.06
0.01
1.5
2.3
—
—
—
0
0
10
103
0.97
0.00
1.5
2.0
—
—
—
0
0
34
336
1.02
0.00
4.4
5.6
2.84
2.04
ug/l
0.31
29
302
0
5
0.00
0.00
0.0
2.0
—
18.10
—
0
5
0
5
0.00
0.00
0.0
1.2
—
0.20
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
0.98
—
0
5
0
5
0.00
0.00
0.0
1.6
—
10.00
—
0
5
0
6
0.00
0.00
0.0
18.5
—
5.65
—
0
6
0
5
0.00
0.00
0.0
1.0
—
104.60
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
150.67
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
1.15
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
13.00
—
0
7
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
6
60
1.00
-0.00
1.2
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_ABSENCE_OF_ONE_KIDNEY_WIDE – Absence of one kidney, including avohilmo
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).