Benign neoplasm of soft tissue of retroperitoneum and peritoneum

CD2_BENIGN_RETROPERITONEUM_PERITONEUM

retroperitoneal cancer: An organ system cancer located_in the retroperitoneal space that is manifested in retroperitoneal space in the abdominal cavity behind the peritoneum.

Suggest a new description

Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D20 Hospital discharge: ICD-9 — 2118 Hospital discharge: ICD-8 — 2117 Cause of death: ICD-10 — D20 Cause of death: ICD-9 — 2118 Cause of death: ICD-8 — 2117 2 out of 7 registries used, show all original rules.	202
4. Check minimum number of events None	202
5. Include endpoints None	202
6. Filter based on genotype QC (FinnGen only)	192

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 2
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D10-D36
Name in latin: Neoplasma benignum telae mollis spatii retroperitonealis et/sive peritonei

NAME	CD2_BENIGN_RETROPERITONEUM_PERITONEUM
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D20
HD_ICD_9	2118
HD_ICD_8	2117
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D20
COD_ICD_9	2118
COD_ICD_8	2117
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm of soft tissue of retroperitoneum and peritoneum based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	1295	851	432
Only index persons	1064	738	326
Unadjusted period prevalence (%)
Whole population	0.02	0.02	0.01
Only index persons	0.02	0.03	0.01
Median age at first event (years)
Whole population	56.26	53.03	62.62
Only index persons	53.21	50.40	59.57

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	192	140	52
Unadjusted period prevalence (%)	0.04	0.05	0.02
Median age at first event (years)	56.20	52.50	66.16

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
193: Matched controls
1930

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D20.0

ICD-10 Finland

Benign neoplasm: Retroperitoneum

+∞

137.5

115

D20.1

ICD-10 Finland

Benign neoplasm: Peritoneum

+∞

61.9

D48.3

ICD-10 Finland

Neoplasm of uncertain or unknown behaviour: Retroperitoneum

234.2

21.0

R19.0

ICD-10 Finland

Intra-abdominal and pelvic swelling, mass and lump

17.2

14.8

JAH01

NOMESCO Finland

Laparoscopy

6.1

14.0

21170

ICD-8 Finland

Benign neoplasm of other parts of digestive system, Peritoneum and retroperitoneal tissue

+∞

11.6

KKB10

NOMESCO Finland

Excision of retroperitoneal tumour

127.3

11.6

WX302

NOMESCO Finland

Thoracal epidural anesthesy

5.6

11.1

JN3BD

NOMESCO Finland

Extensive abdominal CT

3.9

11.1

111

D20

ICD-10 Finland

Benign neoplasm of soft tissue of retroperitoneum and peritoneum

+∞

9.4

JAH00

NOMESCO Finland

Laparotomy

7.7

9.3

UJF32

NOMESCO Finland

Coloscopy

2.5

8.1

343

2118X

ICD-9 Finland

Benign neoplasm of other parts of digestive system, Retroperitoneum and peritoneum[NEOPLASMA BENIGNUM ALIUD SPATII RETROPERITON ET PER]

+∞

7.3

UKC02

NOMESCO Finland

Cystoscopy

2.8

7.3

168

N13.3

ICD-10 Finland

Other and unspecified hydronephrosis

7.5

6.3

KBV02

NOMESCO Finland

Cystoscopic insertion of stent into ureter

9.1

6.2

R10.4

ICD-10 Finland

Other and unspecified abdominal pain

2.1

6.1

519

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma

125

3.31

8.57

4.3

2.3

47.54

40.83

u/ml

0.15

119

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

206

2.85

8.39

3.3

4.3

5.05

9.02

ug/l

0.77

162

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

403

2.46

8.10

3.3

2.2

—

(3044640) Blood type and Crossmatch panel - Blood

560

2.05

5.56

3.7

2.2

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

111

793

1.94

4.81

3.7

2.7

—

estimate

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

6.68

4.03

3.8

3.0

5.08

3.76

nmol/l

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

4.60

3.68

1.1

1.4

2.99

9.04

u/ml

0.52

(3032080) INR in Blood by Coagulation assay

108

811

1.75

3.58

14.0

12.7

1.17

1.22

inr

0.46

664

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

267

1.95

3.55

3.2

2.9

3.55

3.01

e6/l

0.14

132

(3026493) Urate [Moles/volume] in Serum or Plasma

435

1.79

3.41

3.2

2.8

327.75

331.10

umol/l

0.09

376

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

121

950

1.73

3.32

9.2

6.2

11.25

11.01

umol/l

0.11

111

898

(3013707) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method

150

1255

1.88

3.29

5.9

4.3

14.29

12.63

mm/h

0.58

142

1151

(3013650) Neutrophils [#/volume] in Blood by Automated count

123

977

1.71

3.17

11.8

10.5

4.36

4.03

e9/l

0.59

859

(3022313) Gas panel - Capillary blood

2.64

3.14

3.4

3.3

—

(3020779) Urea [Moles/volume] in Serum or Plasma

128

2.19

3.09

8.1

5.2

9.93

10.07

mmol/l

0.03

119

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

209

1.95

3.07

4.3

5.2

32.55

33.26

0.14

132

(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture

6.01

3.05

3.1

2.2

—

(40768804) Tissue Pathology biopsy report

722

1.66

2.98

2.4

2.1

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

395

1.71

2.82

1.7

1.01

1.27

mg/l

0.43

326

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

282

1.78

2.70

3.2

2.8

0.70

0.98

e6/l

0.46

146

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

350

1.71

2.65

1.3

12.46

28.19

iu/ml

1.95

110

(3002256) Pathology report gross observation

236

1.82

2.62

1.3

—

(3045142) Bone marrow Pathology biopsy report

4.80

2.62

2.3

1.3

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

2.98

2.60

1.4

1.8

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

100

778

1.59

2.59

9.5

5.8

1.20

1.21

mmol/l

0.59

715

(3019198) Lymphocytes [#/volume] in Blood

111

886

1.60

2.58

8.1

5.8

1.96

1.92

e9/l

0.15

785

(3004588) Protein electrophoresis panel - Serum or Plasma

124

2.07

2.54

2.6

2.4

—

(3023368) Bacteria identified in Blood by Culture

489

1.60

2.42

3.9

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

553

1.58

2.40

3.8

3.2

1566.24

1308.54

ng/l

0.25

466

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

610

1.56

2.36

4.0

3.1

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

457

1.60

2.33

3.0

2.2

2.61

2.95

mg/l

0.69

393

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

2.21

2.31

1.5

1.3

—

(3001604) Monocytes [#/volume] in Blood

107

861

1.54

2.30

8.2

5.8

0.59

0.58

e9/l

0.23

742

(4062490) Immunoglobulin typing, IgG

4.73

2.29

2.0

1.2

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

150

1306

1.67

2.27

12.4

7.8

87.18

78.98

u/l

0.75

142

1228

(3000570) Elastase.pancreatic [Mass/mass] in Stool

2.51

2.25

1.9

1.3

205.13

291.75

ug/g

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

130

1097

1.57

2.22

5.1

3.3

58.72

44.65

u/l

0.67

124

1036

(3006315) Basophils [#/volume] in Blood

107

868

1.52

2.17

8.2

5.7

0.04

e9/l

0.20

744

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

4.39

2.17

3.2

1.5

—

(3044927) Protein electrophoresis panel - Urine

4.39

2.17

1.0

1.1

—

(4035726) Immunohistochemistry procedure

163

1.84

2.13

1.5

1.4

—

(4281824) Cell count and differential, peritoneal fluid

3.29

2.12

1.3

1.0

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

3.59

2.07

1.1

1.3

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

4.09

2.05

3.2

1.5

—

(3044941) Cell count panel - Synovial fluid

3.16

2.03

2.1

1.4

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

2.72

2.03

2.5

1.4

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

307

1.61

1.95

1.3

14.15

9.02

u/ml

0.17

111

(3002030) Lymphocytes/Leukocytes in Blood

100

814

1.47

1.91

8.8

6.0

27.25

27.46

0.06

772

(3021788) Differential panel - Synovial fluid

2.94

1.88

2.0

1.5

—

(3019225) pH of Specimen

154

1.80

1.88

4.7

4.0

7.38

7.36

0.74

102

(42870588) Differential panel, method unspecified - Blood

570

1.48

1.85

9.7

5.1

—

(3032700) Glomerular basement membrane Ab [Units/volume] in Serum

4.25

1.83

1.0

1.1

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

2.37

1.74

3.1

2.3

122.20

10237.35

u/l

—

(3003396) Base excess in Arterial blood by calculation

190

1.69

1.73

7.0

7.6

0.07

1.02

mmol/l

0.85

166

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

2.11

1.69

1.8

2.6

1.14

0.86

g/l

0.11

(3000991) Gas panel - Venous blood

137

1.77

1.64

11.4

8.3

—

(3013115) Eosinophils [#/volume] in Blood

107

899

1.43

1.64

8.9

6.2

0.20

0.18

e9/l

0.36

788

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

2.40

1.61

1.0

1.2

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

668

1.43

1.61

4.6

3.8

79.06

39.42

ng/l

0.60

469

(3019069) Monocytes/Leukocytes in Blood

803

1.42

1.60

9.4

6.0

8.92

8.86

0.07

751

(36660697) Celiac disease serology panel - Serum

146

1.74

1.60

1.2

1.1

—

(40768795) Lymph node Pathology biopsy report

3.06

1.59

1.8

1.0

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

422

1.46

1.53

2.9

3.9

—

0.25

—

(3019977) pH of Arterial blood

190

1.62

1.48

7.2

7.7

7.41

7.43

0.70

110

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

573

1.41

1.46

4.3

3.0

28.24

31.40

u/l

0.73

541

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

102

863

1.39

1.43

9.8

6.3

1.21

mmol/l

0.36

740

(3022145) Colonoscopy Study observation

209

1.58

1.41

1.2

1.3

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.90

1.40

1.7

2.2

4.04

4.38

g/l

0.67

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.90

1.40

1.7

2.2

7.24

7.41

g/l

0.14

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.90

1.40

1.7

2.2

4.04

3.97

g/l

0.03

(4146454) Self-monitoring of blood glucose

2.99

1.36

2.6

2.7

—

(3050449) Albumin [Mass/time] in Urine collected for unspecified duration

0.00

1.36

0.0

2.6

—

77.05

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

2.20

1.35

1.2

1.4

—

(3022096) Basophils/Leukocytes in Blood

800

1.37

1.35

9.5

5.9

0.82

0.68

2.27

745

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

106

1.77

1.35

1.7

1.8

—

(3006504) Eosinophils/Leukocytes in Blood

801

1.37

1.34

9.4

5.8

3.29

2.69

1.28

750

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

122

1.71

1.33

1.5

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

2.41

1.31

2.0

1.4

—

(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.88

1.29

1.8

2.3

2.77

3.04

g/l

0.55

(3018095) Leukocytes [#/volume] in Urine

651

1.36

1.27

5.0

4.0

33.85

73.21

e6/l

1.12

454

(3003327) Ova and parasites identified in Stool by Light microscopy

1.96

1.26

2.0

1.6

—

(40768443) Skin Pathology biopsy report

1.81

1.23

1.4

1.2

—

(3002582) Erythrocytes [#/volume] in Urine

561

1.36

1.20

4.5

3.2

17.07

170.77

e6/l

0.73

430

(3042936) Bacteria identified in Isolate by Culture

253

1.47

1.18

3.2

2.0

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

228

1.48

1.15

11.8

6.4

105.81

104.52

mmol/l

1.51

228

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

777

1.32

1.12

3.4

2.5

77.74

78.73

nmol/l

0.12

690

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

372

1.39

1.11

1.9

1.8

239535304.16

470.80

pmol/l

0.49

310

(3038177) Helicobacter pylori Ab [Presence] in Serum

2.42

1.09

1.0

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

170

1600

1.52

1.09

25.5

16.0

25.52

23.30

mg/l

0.39

152

1335

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

1.97

1.08

1.8

1.5

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

163

1523

1.45

1.07

7.0

5.7

2.07

1.93

mu/l

0.25

154

1397

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

2.31

1.04

1.8

1.2

—

(3009261) Glucose [Presence] in Urine by Test strip

107

942

1.30

1.03

4.3

4.1

0.18

0.00

estimate

0.48

183

(3007566) Smooth muscle Ab [Titer] in Serum

1.92

1.02

1.0

1.2

—

86.25

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

1.72

1.01

1.1

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

1.88

1.00

1.0

1.3

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

232

0.62

0.99

3.4

4.7

22.49

21.69

—

116

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

2.20

0.98

1.0

1.2

—

nmol/l

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

2.20

0.98

1.8

1.2

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

2.20

0.98

1.8

1.2

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

2.20

0.98

1.8

1.2

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

2.20

0.98

1.8

1.2

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

2.20

0.98

1.8

1.2

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

141

1294

1.33

0.98

5.8

4.6

14.94

14.77

pmol/l

0.37

131

1179

(3019060) Gas panel - Arterial blood

1.66

0.97

5.3

4.3

—

(3015736) pH of Urine

741

1.29

0.96

3.6

6.23

6.21

0.05

394

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

1.80

0.96

1.7

1.5

—

(1616796) Gas panel - Central venous blood

1.92

0.95

3.7

2.8

—

(3049717) Cytology report of Urine Cyto stain

1.77

0.94

2.7

2.9

—

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

1.77

0.94

2.0

2.3

1.52

1.45

mg/l

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

152

0.57

0.93

1.2

1.8

—

(40761511) CBC panel - Blood by Automated count

172

1634

1.48

0.92

19.4

14.3

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

205

1.43

0.90

8.3

6.7

—

(3021601) Nitrite [Presence] in Urine by Test strip

104

924

1.27

0.89

4.3

4.0

0.00

estimate

-0.00

195

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.71

0.87

1.5

2.2

9.82

9.97

g/l

0.07

(3030467) Casts [#/volume] in Urine by Automated count

484

1.28

0.81

4.7

3.1

0.67

0.51

e6/l

0.19

351

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.79

0.0

1.1

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

308

0.71

0.77

1.7

1.5

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.61

0.77

1.5

1.9

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

1.73

0.76

1.2

—

(3021960) Folate [Moles/volume] in Serum or Plasma

545

1.26

0.76

1.9

1.7

19.31

21.37

nmol/l

0.52

447

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

1.70

0.73

1.6

2.5

0.00

g/l

—

(3001334) Neutrophil cytoplasmic Ab [Units/volume] in Serum

1.61

0.72

1.1

1.4

—

(40764999) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M

165

1572

1.34

0.71

22.7

15.8

77.19

79.67

ml/min/173m2

0.76

157

1463

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

1.87

0.69

5.0

3.6

49.68

53.88

u/ml

—

(46236952) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)/1.73 sq M

146

1.41

0.67

2.6

2.8

72.33

67.65

ml/min/173m2

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

412

1.25

0.64

1.4

1.3

0.58

1.88

u/ml

1.39

112

(3023511) Choriogonadotropin [Units/volume] in Urine

1.74

0.64

1.2

1.4

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

113

1.45

0.63

1.3

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

1.62

0.63

1.6

1.4

—

(3022621) pH of Urine by Test strip

157

1.38

0.62

2.2

2.7

5.89

6.11

0.59

104

(44806420) Estimation of glomerular filtration rate

0.00

0.60

0.0

2.5

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

167

1.36

0.60

1.7

1.4

—

(40768797) Stomach Pathology biopsy report

258

1.29

0.59

1.2

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

115

1.43

0.59

1.2

323.16

142.37

u/ml

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

287

1.27

0.57

2.3

1.9

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

1.47

0.57

1.5

1.2

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.57

0.56

1.7

1.9

—

(40761536) Microorganisms panel - Urine sediment

147

0.66

0.56

10.3

3.6

—

(3019150) Specific gravity of Urine by Refractometry

401

1.23

0.54

3.7

4.2

1.02

kg/l

0.18

260

(3035350) Ketones [Presence] in Urine by Test strip

102

937

1.19

0.54

4.3

4.0

0.00

8.12

estimate

0.50

200

(3019309) Folate [Moles/volume] in Red Blood Cells

308

1.25

0.53

2.3

1.7

1244.67

1214.30

nmol/l

0.07

233

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.56

0.53

1.0

1.3

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

135

1.37

0.53

1.2

1.4

—

(40758558) Short blood count panel - Blood

519

1.20

0.51

8.8

6.5

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

166

0.70

0.50

1.3

1.8

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

716

1.17

0.48

1.8

2.0

1.45

1.31

mmol/l

0.50

592

(3001019) Free T4 and TSH panel - Serum or Plasma

0.60

0.47

1.4

2.2

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

211

1.27

0.46

2.2

1.8

—

(4024509) Urine culture

0.58

0.46

1.8

1.7

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

767

1.17

0.46

2.5

2.2

102.97

98.72

pmol/l

0.24

375

(3012544) pH of Venous blood

158

1.30

0.44

8.8

3.2

7.39

—

(3026782) Osmolality of Urine

335

1.21

0.43

3.8

2.9

505.62

515.80

mosm/kgh2o

0.09

297

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.45

0.42

1.3

1.8

—

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

1.40

0.42

2.1

4.8

24.00

65.37

mg/l

—

(3034860) Kappa light chains.free [Mass/volume] in Serum

1.40

0.42

2.1

4.8

135.50

169.19

mg/l

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

106

991

1.15

0.42

3.4

3.1

—

(3007164) IgA [Mass/volume] in Serum or Plasma

384

1.19

0.41

1.8

1.4

2.01

2.57

g/l

0.95

227

(3009595) Pneumocystis jirovecii DNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.6

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

17.6

—

904.53

—

(3000242) Tau protein [Mass/volume] in Cerebral spinal fluid

0.00

0.40

0.0

1.1

—

262.67

—

(3042810) Amyloid beta 42 peptide [Mass/volume] in Cerebral spinal fluid

0.00

0.40

0.0

1.1

—

575.50

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.40

0.0

1.3

—

(43055225) Phosphorylated tau 181 [Mass/volume] in Cerebral spinal fluid by Immunoassay

0.00

0.40

0.0

1.1

—

34.76

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.39

0.0

1.2

—

(21494755) Public health laboratory ask at order entry panel

136

0.72

0.39

1.2

1.3

—

(3017181) Myelocytes/Leukocytes in Blood

152

1.28

0.38

5.3

5.1

0.86

0.85

—

(3021440) Promyelocytes/Leukocytes in Blood

143

1.29

0.38

5.3

5.2

0.00

0.10

—

(3041096) Erythrocytes [Presence] in Urine by Automated

507

0.85

0.38

5.4

3.5

0.00

estimate

-0.00

152

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

181

1.24

0.36

4.0

3.6

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

380

1.17

0.35

2.5

2.8

2.45

2.46

mmol/l

0.09

341

(3026361) Erythrocytes [#/volume] in Blood

177

1731

1.27

0.35

37.0

24.8

4.33

4.41

e12/l

1.55

172

1685

(3010813) Leukocytes [#/volume] in Blood

177

1731

1.27

0.35

37.1

24.9

6.99

6.64

e9/l

1.14

172

1684

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

337

0.84

0.35

1.2

1.5

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

352

1.17

0.34

4.5

3.9

306.51

267.47

ng/l

0.06

278

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

201

1.22

0.34

9.6

4.4

242.83

255.62

u/l

0.29

188

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

165

0.77

0.33

1.5

2.0

—

(3026008) Bacteria identified in Urine by Culture

579

1.13

0.30

3.4

3.1

—

(3025159) Blasts/Leukocytes in Blood

148

1.24

0.30

5.4

5.8

0.00

0.03

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

157

1525

1.16

0.30

6.9

6.4

39.08

39.22

mmol/mol

0.08

149

1436

(3018418) pH of Serum or Plasma

532

1.13

0.29

7.6

3.8

7.40

0.32

379

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

1.30

0.27

7.0

2.3

0.50

0.61

0.83

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

161

1571

1.15

0.26

5.6

5.3

5.77

5.91

mmol/l

0.75

152

1443

(3030981) Hyaline casts [#/volume] in Urine by Automated count

133

1.22

0.25

2.3

2.4

0.14

1.21

e6/l

0.82

125

(1761868) Lipid panel - Serum or Plasma

594

0.90

0.25

3.1

3.4

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.28

0.25

7.0

2.4

0.89

1.15

0.68

(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma

1.30

0.24

2.3

2.1

34.50

41.72

u/l

—

(3037756) Immunofixation for Serum or Plasma

1.36

0.23

2.2

1.6

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.75

0.23

1.3

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

162

1585

1.14

0.22

5.4

5.3

4.62

4.69

mmol/l

0.39

155

1468

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

1.23

0.22

1.8

1.5

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.21

0.0

1.4

—

(3016750) Collection duration of Urine

0.00

0.21

0.0

2.5

—

498.00

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

0.21

0.0

7.2

—

8.72

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.0

—

(3029536) Hepatitis C virus RNA [Units/volume] (viral load) in Specimen by NAA with probe detection

0.00

0.21

0.0

1.1

—

(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose

0.00

0.21

0.0

1.6

—

7.36

—

(3004775) Volume in Urine collected for unspecified duration

0.00

0.21

0.0

2.6

—

623.17

—

(1761482) Bacteria [#/volume] in Urine by Culture

1.17

0.21

10.6

4.0

—

(3006442) Creatine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.7

—

68.85

—

(3007853) Bacteria identified in Skin by Aerobe culture

193

1.16

0.20

2.1

1.6

—

(40760543) Extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.20

0.0

1.1

—

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.20

0.0

1.1

—

10.20

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

143

0.83

0.19

4.0

4.1

1.22

mmol/l

0.15

123

(3000850) Epithelial cells [#/volume] in Urine

378

1.11

0.19

3.9

2.7

6.14

5.53

e6/l

0.15

350

(3019832) Treponema pallidum Ab [Presence] in Serum

110

1.19

0.17

1.3

1.8

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

1.12

0.17

2.4

1.8

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.73

0.17

1.4

1.5

—

(3029937) Albumin [Presence] in Urine by Test strip

528

1.09

0.17

4.3

3.9

0.00

0.01

estimate

0.50

180

(46235355) HIV 1 and 2 tests - Meaningful Use set

275

0.90

0.15

1.8

—

(3002179) Metamyelocytes/Leukocytes in Blood

140

1.16

0.15

6.0

5.3

0.50

0.78

—

(3025941) Bacteria identified in Stool by Culture

102

1.19

0.15

1.3

1.2

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

113

1.16

0.13

2.0

1.3

—

(40760892) CBC W Ordered Manual Differential panel - Blood

403

0.93

0.12

5.9

5.2

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

696

0.94

0.11

4.9

4.0

0.07

0.02

estimate

0.30

158

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

231

1.09

0.11

2.0

1.5

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

1.09

0.09

2.2

1.2

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

1.11

0.09

1.2

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

1.05

0.08

1.2

—

(42529406) Shigella sp [Presence] in Stool by Culture

1.05

0.08

1.2

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

1.04

0.08

1.2

—

(3021589) Normoblasts [#/volume] in Blood

769

0.96

0.07

15.3

11.4

0.00

e9/l

1.26

627

(3000494) Fungus identified in Specimen by Culture

216

1.07

0.07

1.4

—

(3003694) ABO and Rh group [Type] in Blood

467

0.95

0.07

1.6

1.4

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

151

1498

1.04

0.04

4.6

4.4

1.25

mmol/l

0.00

142

1375

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

159

1579

1.04

0.04

5.2

1.51

1.53

mmol/l

0.31

151

1458

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

160

1607

0.97

0.01

6.2

6.1

2.65

2.73

mmol/l

0.55

152

1484

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

144

1.05

0.00

1.3

1.4

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

204

0.98

0.00

2.4

1.9

—

(3020682) Albumin/Creatinine [Ratio] in Urine

546

1.01

0.00

4.5

3.9

13.82

7.72

mg/mmol

0.48

308

(3009508) Creatinine [Moles/volume] in Urine

567

1.01

0.00

3.4

3.0

6.94

7.16

mmol/l

0.17

465

(3012516) Albumin [Mass/volume] in Urine

545

0.99

0.00

3.7

3.1

76.43

47.95

mg/l

0.35

325

(3000492) Spirometry study

162

0.99

0.00

1.3

1.5

—

(4034850) Laboratory test

0.91

0.00

14.4

10.4

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.90

-0.00

1.1

1.0

—

(3013637) Mi-2 Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

-0.00

0.0

1.3

—

(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

0.33

—

(3051651) Icteric interference index of Serum or Plasma

0.00

-0.00

0.0

3.4

—

0.86

—

(3001964) Herpes simplex virus Ag [Presence] in Specimen

0.00

-0.00

0.0

1.5

—

(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3044936) Clostridioides difficile toxin A+B [Presence] in Stool by Immunoassay

0.00

-0.00

0.0

1.4

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

-0.00

0.0

1.0

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

5.0

—

9.97

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

-0.00

0.0

1.6

—

108.60

—

(3034988) Calcium [Moles/volume] in Capillary blood

0.00

-0.00

0.0

1.2

—

1.21

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

-0.00

0.0

1.1

—

(3033306) Mononuclear cells/Leukocytes in Cerebral spinal fluid

0.00

-0.00

0.0

1.1

—

(3030558) Cytomegalovirus DNA [Units/volume] (viral load) in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

229.43

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

5.0

—

4.71

—

(3043410) Blood group antigens tested for on Red Blood Cells

0.00

-0.00

0.0

1.2

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

-0.00

0.0

1.0

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.2

—

(3008898) HLA-B27 [Presence]

0.94

-0.00

1.0

1.1

—

(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture

0.00

-0.00

0.0

1.1

—

(42529582) MDA5 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.00

-0.00

3.0

2.5

—

(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

1951.86

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

-0.00

0.0

1.1

—

(3002619) Bacteria identified in Specimen by Culture

0.00

-0.00

0.0

1.2

—

(42868766) Dientamoeba fragilis DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3020650) Glucose [Presence] in Urine

0.00

-0.00

0.0

1.0

—

0.00

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3005011) Chlamydia sp Ab [Titer] in Serum

0.00

-0.00

0.0

1.4

—

(3038769) Chlamydophila pneumoniae IgG Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

15.30

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_RETROPERITONEUM_PERITONEUM and mortality.

Females

Parameter	HR [95% CI]	p-value
CD2_BENIGN_RETROPERITONEUM_PERITONEUM	2.385 [1.89, 3.01]	< 0.001
Birth year	0.993 [0.98, 1.0]	0.1

During the follow-up period (1.1.1998 — 31.12.2019), 150 out of 605 females with CD2_BENIGN_RETROPERITONEUM_PERITONEUM died.

Males

Parameter	HR [95% CI]	p-value
CD2_BENIGN_RETROPERITONEUM_PERITONEUM	1.881 [1.45, 2.44]	< 0.001
Birth year	0.987 [0.98, 1.0]	0.007

During the follow-up period (1.1.1998 — 31.12.2019), 136 out of 336 males with CD2_BENIGN_RETROPERITONEUM_PERITONEUM died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_RETROPERITONEUM_PERITONEUM.

N-year risk	Females	Males
1	0.204%	0.449%
5	1.191%	2.385%
10	3.436%	5.42%
15	6.315%	9.864%
20	10.745%	16.087%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_RETROPERITONEUM_PERITONEUM – Benign neoplasm of soft tissue of retroperitoneum and peritoneum

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm of soft tissue of retroperitoneum and peritoneum

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints