No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
194 |
4. Check minimum number of eventsNone |
194 |
5. Include endpointsNone |
194 |
6. Filter based on genotype QC (FinnGen only) |
172 |
Control definitions (FinnGen only)
- Control exclude
- AB1_INTESTINAL_INFECTIONS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Typhoid and paratyphoid fevers
based on the number of shared cases.
Similar with more cases:
- Typhoid and paratyphoid fevers, including avohilmo
- Intestinal infectious diseases
- Intestinal infectious diseases, including avohilmo, including avohilmo
- Certain infectious and parasitic diseases
- Certain infectious and parasitic diseases, including avohilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1560 | 772 | 765 |
| Only index persons | 1249 | 640 | 609 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 34.76 | 36.42 | 32.62 |
| Only index persons | 29.08 | 30.04 | 28.08 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 172 | 103 | 69 |
| Unadjusted period prevalence (%) | 0.03 | 0.04 | 0.03 |
| Median age at first event (years) | 40.15 | 38.24 | 42.99 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 181
- Matched controls
- 1810
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
00210
ICD-8 Finland
Paratyphoid fever B
+∞
30.0
28
*
A01.0
ICD-10 Finland
Typhoid fever
+∞
28.9
27
*
A01.4
ICD-10 Finland
Paratyphoid fever, unspecified
+∞
14.8
14
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
4.6
14.0
39
103
00299
ICD-8 Finland
Paratyphoid fever unspecified
+∞
12.6
12
*
M01.3*A01.4
ICD-10 Finland
Arthritis in typhoid or paratyphoid fever
+∞
11.6
11
*
I39.8*A01.0
ICD-10 Finland
Endocarditis in typhoid fever
+∞
11.6
11
*
00199
ICD-8 Finland
Typhoid fever, Unspecified
+∞
9.5
9
*
A01.1
ICD-10 Finland
Paratyphoid fever A
+∞
8.4
8
*
R50.9
ICD-10 Finland
Fever, unspecified
3.1
8.0
40
154
0022A
ICD-9 Finland
Typhoid and paratyphoid fevers, Paratyphoid fever B
+∞
7.3
7
*
0029X
ICD-9 Finland
Typhoid and paratyphoid fevers, Paratyphoid fever, unspecified
+∞
7.3
7
*
00220
ICD-8 Finland
Paratyphoid fever C
+∞
7.3
7
*
0020A
ICD-9 Finland
Typhoid and paratyphoid fevers, Typhoid fever
+∞
7.3
7
*
J01MA02
ATC
ciprofloxacin; systemic
2.2
6.0
78
466
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
25
94
2.93
5.17
1.8
1.4
—
—
—
0
0
101
699
2.01
5.00
2.9
2.4
80.78
77.54
nmol/l
0.48
93
636
13
31
4.44
4.10
1.3
1.2
—
—
—
0
0
18
66
2.92
3.88
3.8
3.3
1.72
1.51
%
0.50
18
61
100
772
1.66
2.83
10.3
5.9
1.20
1.21
mmol/l
0.81
95
662
54
357
1.73
2.73
1.3
1.3
0.51
1.38
u/ml
1.35
11
97
8
20
4.13
2.60
1.9
1.6
81.49
52.65
ug/l
—
8
15
111
894
1.62
2.55
13.6
10.1
3.78
3.99
e9/l
0.58
102
787
11
38
3.01
2.46
1.3
1.2
—
—
—
0
0
112
913
1.59
2.37
7.9
4.3
6.47
6.59
mmol/l
0.25
104
853
10
35
2.96
2.24
1.2
1.3
—
—
—
0
0
26
147
1.90
2.17
4.8
3.0
5.98
5.83
kpa
0.39
26
142
86
670
1.54
2.15
2.4
2.0
93.01
98.59
pmol/l
0.47
48
363
105
855
1.54
2.14
6.7
5.9
9.89
11.09
umol/l
1.52
99
813
16
76
2.21
2.09
1.0
1.1
—
—
—
0
0
91
721
1.53
2.09
3.7
3.0
157.26
118.03
ug/l
0.29
84
676
7
20
3.60
2.07
8.3
4.6
—
—
—
0
0
90
722
1.49
1.89
4.3
2.6
—
—
estimate
—
0
0
37
243
1.66
1.88
2.0
1.9
—
—
—
0
0
88
704
1.49
1.87
8.5
5.4
1.19
1.21
mmol/l
1.08
83
653
62
462
1.52
1.85
1.7
1.6
20.06
20.91
nmol/l
0.20
57
391
33
213
1.67
1.79
10.8
5.7
104.79
103.78
mmol/l
0.66
33
213
29
182
1.71
1.74
1.9
1.8
—
—
—
0
0
8
31
2.65
1.68
1.1
1.2
—
—
—
0
0
10
43
2.40
1.61
1.4
1.3
—
—
—
0
0
10
43
2.40
1.61
2.4
1.5
—
—
—
0
0
135
1205
1.47
1.46
10.1
7.4
79.85
79.27
u/l
0.06
129
1142
28
185
1.61
1.40
2.0
1.7
—
—
—
0
0
47
349
1.47
1.39
2.7
2.3
—
—
—
0
0
49
375
1.42
1.24
2.0
1.6
0.95
1.28
mg/l
0.51
37
304
14
79
1.84
1.21
1.6
1.3
—
—
—
0
0
37
270
1.47
1.20
3.8
2.7
0.93
1.13
e6/l
0.22
20
139
0
33
0.00
1.17
0.0
1.8
—
—
—
0
0
35
254
1.47
1.16
4.1
2.9
4.23
3.88
e6/l
0.04
18
120
41
307
1.43
1.16
4.2
3.8
2476.07
309.59
ng/l
0.44
27
242
77
645
1.34
1.11
4.9
3.9
0.00
0.05
estimate
1.15
13
151
8
41
1.99
1.10
1.6
1.3
—
41.47
—
0
6
5
21
2.42
1.10
1.0
1.5
—
—
—
0
0
49
383
1.38
1.09
2.8
2.1
2.34
3.01
mg/l
1.22
44
332
7
32
2.23
1.09
1.7
1.5
—
—
—
0
0
10
52
1.98
1.08
3.7
1.9
—
—
—
0
0
7
36
1.98
0.98
1.7
1.5
—
—
—
0
0
157
1477
1.47
0.97
5.5
5.0
6.03
5.93
mmol/l
0.34
150
1367
6
29
2.10
0.90
1.8
1.1
1.05
0.83
nmol/l
—
6
24
8
45
1.81
0.85
1.5
1.1
—
—
—
0
0
8
45
1.81
0.85
1.5
1.1
—
—
—
0
0
153
1445
1.38
0.80
6.5
6.1
38.55
39.21
mmol/mol
0.50
148
1360
96
855
1.26
0.80
5.1
3.9
0.00
0.00
estimate
-0.00
23
178
0
26
0.00
0.79
0.0
1.5
—
54.81
—
0
26
57
479
1.28
0.76
4.8
3.4
0.00
0.02
estimate
0.74
15
134
37
293
1.33
0.76
1.5
1.3
9.69
13.68
u/ml
0.18
15
109
20
142
1.46
0.76
3.5
2.5
0.26
0.21
e6/l
0.11
20
132
40
321
1.32
0.75
1.6
1.3
46.13
25.04
iu/ml
—
9
104
12
76
1.62
0.73
1.8
1.3
—
—
—
0
0
5
26
1.95
0.71
1.0
1.5
—
—
—
0
0
5
26
1.95
0.71
1.0
1.5
—
—
—
0
0
7
41
1.74
0.71
1.7
1.5
—
—
—
0
0
13
86
1.55
0.68
20.1
8.5
25.45
24.35
mmol/l
0.68
13
86
13
86
1.55
0.68
2.1
2.5
—
—
—
0
0
8
52
1.56
0.60
3.1
2.9
—
—
—
0
0
56
483
1.23
0.59
3.7
3.8
3.55
9.17
mg/mmol
1.84
30
303
8
53
1.53
0.59
2.3
1.6
89.63
94.17
%
—
8
53
31
249
1.30
0.59
1.5
1.9
874.73
1209.43
nmol/l
1.53
26
190
93
846
1.20
0.58
5.3
3.9
0.00
0.00
estimate
-0.00
22
172
95
866
1.20
0.58
5.2
3.9
0.18
0.02
estimate
0.40
22
169
56
489
1.21
0.53
3.4
2.3
52.86
64.69
u/l
0.64
49
449
13
92
1.45
0.52
5.8
2.9
25.02
24.65
mmol/l
0.19
13
92
7
45
1.58
0.49
1.7
1.5
—
—
—
0
0
7
45
1.58
0.49
1.7
2.1
—
—
—
0
0
7
47
1.51
0.48
1.9
2.4
—
—
—
0
0
12
86
1.42
0.46
1.6
1.8
—
—
—
0
0
13
96
1.38
0.43
3.5
3.3
4.53
4.41
pmol/l
0.21
13
85
5
32
1.58
0.42
2.0
1.6
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
48.79
—
0
9
0
17
0.00
0.41
0.0
1.0
—
452.78
—
0
9
5
34
1.48
0.40
1.0
1.1
785.40
528.68
mg/l
—
5
34
134
1283
1.17
0.38
29.2
19.5
331.90
332.03
g/l
0.05
134
1278
60
543
1.16
0.37
3.6
3.0
2.36
2.36
mmol/l
0.04
55
503
66
602
1.15
0.37
4.1
3.6
22.68
38.07
ng/l
0.84
49
411
6
46
1.31
0.33
1.5
1.4
—
—
—
0
0
90
954
0.89
0.31
3.6
3.1
—
—
—
0
0
152
1479
1.17
0.29
17.7
14.7
83.40
81.07
ml/min/173m2
0.71
140
1379
10
77
1.32
0.26
2.1
2.5
—
—
—
0
0
49
449
1.13
0.25
4.3
2.9
0.05
0.51
e6/l
3.59
36
325
43
392
1.13
0.24
3.9
4.0
1.02
1.02
kg/l
1.04
33
271
147
1433
1.14
0.24
4.4
4.3
1.44
1.28
mmol/l
1.26
137
1326
154
1506
1.15
0.23
5.4
5.1
4.72
4.68
mmol/l
0.16
146
1408
156
1527
1.16
0.23
6.2
5.8
2.71
2.74
mmol/l
0.15
146
1429
0
11
0.00
0.21
0.0
5.4
—
1038.27
—
0
11
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.3
—
13.50
—
0
12
5
43
1.17
0.21
1.0
1.4
8.86
10.04
g/l
—
5
38
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
14
162
0.85
0.17
8.8
7.0
—
—
—
0
0
22
244
0.89
0.15
1.4
1.5
—
—
—
0
0
16
181
0.87
0.15
4.1
4.6
39.64
32.09
%
1.33
11
118
37
345
1.09
0.14
1.5
1.8
429.55
16892342.25
pmol/l
0.50
31
296
152
1498
1.09
0.12
5.3
5.0
1.51
1.48
mmol/l
0.37
143
1393
26
281
0.91
0.12
3.0
3.0
0.65
0.88
ug/l
0.76
18
162
154
1521
1.08
0.10
23.5
14.7
24.55
23.09
mg/l
0.21
134
1233
5
48
1.04
0.09
1.0
1.3
—
—
—
0
0
46
477
0.95
0.07
4.2
4.1
0.00
0.01
estimate
0.50
23
159
67
654
1.04
0.06
2.1
1.9
1.37
1.37
mmol/l
0.01
60
553
29
303
0.95
0.05
1.8
1.6
—
—
—
0
0
17
178
0.95
0.02
1.9
2.3
—
—
—
0
0
107
1078
0.98
0.01
3.8
3.1
57.14
46.36
u/l
0.57
99
1009
14
134
1.05
0.00
2.2
1.4
—
—
—
0
0
15
154
0.97
0.00
3.0
3.3
—
—
—
0
0
17
166
1.03
0.00
1.9
2.2
—
—
—
0
0
35
354
0.99
0.00
4.5
4.6
22.23
22.00
%
0.02
16
167
128
1284
0.99
0.00
30.2
19.2
13.55
13.58
%
0.11
128
1275
100
1002
1.00
0.00
6.9
4.5
—
334.18
—
0
22
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
1668.20
—
0
5
0
5
0.00
0.00
0.0
1.6
—
67.80
—
0
5
0
5
0.00
0.00
0.0
1.0
—
9.94
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
52.40
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.5
—
155.45
—
0
8
0
9
0.00
-0.00
0.0
2.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
5.2
—
226.78
—
0
9
6
59
1.02
-0.00
1.0
1.1
0.94
0.90
g/l
—
6
59
6
59
1.02
-0.00
1.0
1.1
1.59
1.57
g/l
—
6
59
Mortality – FinRegistry
↥Association
Association between endpoint AB1_TYPHOIDPARATHYPHOID and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have AB1_TYPHOIDPARATHYPHOID.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: AB1_TYPHOIDPARATHYPHOID – Typhoid and paratyphoid fevers
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data