Gout due to impairment of renal function

GOUT_KIDNEY

gout: A condition characterized by painful swelling of the joints, which is caused by deposition of urate crystals.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M10.3
  • Cause of death: ICD-10 M10.3

2 out of 7 registries used, show all original rules.

447

4. Check minimum number of events

None

447

5. Include endpoints

None

447

6. Filter based on genotype QC (FinnGen only)

391

Control definitions (FinnGen only)

Control exclude
GOUT

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M10
Name in latin
Arthritis urica ex insufficientia renali

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1900 646 1244
Only index persons 1736 586 1150
Unadjusted period prevalence (%)
Whole population 0.03 0.02 0.03
Only index persons 0.04 0.02 0.04
Median age at first event (years)
Whole population 73.96 77.27 72.23
Only index persons 73.66 76.82 72.05

-FinnGen-

Key figures

All Female Male
Number of individuals 391 103 288
Unadjusted period prevalence (%) 0.11 0.04 0.13
Median age at first event (years) 71.54 74.08 70.63

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
407
Matched controls
4070
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M10.9
ICD-10 Finland
Gout, unspecified
53.9
307.7
227
93
M04AA01
ATC
allopurinol; systemic
89.7
307.7
362
335
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
52.7
307.7
282
167
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
91.8
307.7
194
40
M10.3
ICD-10 Finland
Gout due to impairment of renal function
+∞
307.7
407
*
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
89.7
307.7
181
36
A11CC03
ATC
alfacalcidol; systemic
72.3
298.7
170
40
N18.8
ICD-10 Finland
Other chronic renal failure
74.3
292.6
165
37
A12AA04
ATC
calcium carbonate; oral
79.1
237.3
130
24
TK800
NOMESCO Finland
Hemodialysis
44.5
205.4
129
42
N18.0
ICD-10 Finland
End-stage renal disease
100.2
177.9
93
12
Z49.1
ICD-10 Finland
Extracorporeal dialysis
54.9
171.2
100
24
B03XA02
ATC
darbepoetin alfa; parenteral
38.9
166.0
107
37
127
Kela drug reimbursment
Transplant complication
69.6
166.0
92
17
L04AA06
ATC
mycophenolic acid; systemic
51.3
165.2
98
25
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
75.7
163.1
89
15
M10.0
ICD-10 Finland
Idiopathic gout
32.0
146.1
100
41
Z49.0
ICD-10 Finland
Preparatory care for dialysis
84.7
142.2
76
11
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
79.3
133.4
72
11
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
69.0
125.0
69
12
137
Kela drug reimbursment
Uraemia requiring dialysis
75.8
117.8
64
10
C03CA01
ATC
furosemide; systemic
13.9
115.3
344
1150
N19
ICD-10 Finland
Unspecified kidney failure
14.8
112.6
114
104
L04AD02
ATC
tacrolimus; systemic
68.8
106.9
59
10
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
52.9
101.5
59
13
V03AE01
ATC
polystyrene sulfonate; oral
36.0
99.4
64
21
N18.4
ICD-10 Finland
Chronic kidney disease, stage 4
36.0
99.4
64
21
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
11.0
91.1
113
137
Z94.0
ICD-10 Finland
Kidney transplant status
128.0
86.0
90
9
M10
ICD-10 Finland
Gout
14.2
84.5
84
73
205
Kela drug reimbursment
Chronic hypertension
7.1
83.8
274
914
212
Kela drug reimbursment
Gout
+∞
81.0
75
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
10.9
76.8
93
108
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
6.8
73.6
157
346
L04AD01
ATC
ciclosporin; systemic
27.6
73.0
51
21
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
152.7
72.7
75
6
C02AC05
ATC
moxonidine; oral
9.9
70.7
92
117
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
23.2
68.2
51
25
T92
ICPC
Gout
20.2
66.5
53
30
I12.0
ICD-10 Finland
Hypertensive renal disease with renal failure
25.8
64.4
46
20
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
7.8
64.2
105
174
I50.9
ICD-10 Finland
Heart failure, unspecified
5.6
64.1
187
539
KA1AE
NOMESCO Finland
Kidney ultrasound examination
14.5
62.9
60
48
B03XA01
ATC
erythropoietin; parenteral
28.4
59.6
41
16
A46
ICD-10 Finland
Erysipelas
5.6
59.0
156
409
H02AB04
ATC
methylprednisolone; systemic
5.8
58.1
140
338
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
9.7
57.0
73
90
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
129.5
53.3
56
5
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
155.1
52.2
54
*
288
Kela drug reimbursment
Febuxostat
+∞
50.0
47
*
C08CA01
ATC
amlodipine; oral
4.9
49.9
289
1358
I50.0
ICD-10 Finland
Congestive heart failure
5.8
49.7
110
243
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.2
49.5
133
348
H02AB06
ATC
prednisolone; systemic
4.8
46.7
295
1451
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.5
46.0
167
550
H05BX01
ATC
cinacalcet; oral
111.1
45.9
49
5
M13.9
ICD-10 Finland
Arthritis, unspecified
7.0
45.7
78
133
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
6.3
44.8
86
165
C07AG02
ATC
carvedilol; oral
6.5
44.7
83
154
ZX120
NOMESCO Finland
Intravenous
5.6
44.5
102
231
C08CA13
ATC
lercanidipine; oral
4.6
44.3
140
414
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
7.7
43.9
67
101
196
Kela drug reimbursment
Paricalcitol and cinacalcet
106.0
43.8
47
5
349
Kela drug reimbursment
Febuxostat
+∞
43.5
41
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
10.6
43.3
50
53
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.0
42.5
229
987
M04AA03
ATC
febuxostat; oral
+∞
42.4
40
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.6
42.0
129
371
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
233.5
41.7
42
*
A10BH05
ATC
linagliptin; oral
6.2
41.4
80
154
Z49.2
ICD-10 Finland
Other dialysis
73.8
41.0
46
7
B05DA
ATC
Isotonic solutions
72.0
40.0
45
7
U14
ICPC
Kidney symptom/complaint
11.9
39.7
42
39
TPH04
NOMESCO Finland
Cathetrisation of vein
4.0
39.7
173
639
V03AE02
ATC
sevelamer; oral
151.5
39.5
41
*
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
57.4
39.5
46
9
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.7
39.3
115
317
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
4.7
38.6
109
292
C08CA02
ATC
felodipine; oral
4.8
38.4
104
269
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.3
38.0
307
1696
A10AC01
ATC
insulin (human); parenteral
5.4
37.8
86
192
B05DB
ATC
Hypertonic solutions
77.7
37.7
42
6
E87.5
ICD-10 Finland
Hyperkalaemia
12.2
37.7
39
35
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
47.9
35.8
43
10
321
Kela drug reimbursment
Paricalcitol and cinacalcet
86.2
35.5
39
5
JN3AD
NOMESCO Finland
Abdominal CT examination
4.3
35.3
114
337
C09AA02
ATC
enalapril; systemic
3.7
35.2
164
625
C09CA01
ATC
losartan; oral
3.5
34.6
193
825
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
101.5
34.3
37
*
L04AA01
ATC
[U] ciclosporin
42.3
34.1
42
11
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
13.2
33.7
33
27
B01AA03
ATC
warfarin; systemic
3.5
33.1
170
686
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.3
31.7
202
926
I10
ICD-10 Finland
Essential (primary) hypertension
4.9
30.3
353
2322
R4110
NOMESCO Finland
Physiotherapy
3.3
30.2
179
781
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
7.7
29.9
44
63
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.3
29.7
66
143
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
10.0
29.6
35
38
R50.9
ICD-10 Finland
Fever, unspecified
3.8
29.3
116
391
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
161.5
29.1
30
*
R4190
NOMESCO Finland
Nutritional therapy
7.4
28.6
44
66
V03AE03
ATC
lanthanum carbonate; oral
69.2
28.4
32
5
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.2
28.2
180
813
215
Kela drug reimbursment
Diabetes, non-insulin-treated
3.2
28.2
176
785
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
6.5
28.1
49
84
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
32.7
27.7
36
12
C07AB07
ATC
bisoprolol; oral
3.4
27.6
296
1789
N18.3
ICD-10 Finland
Chronic kidney disease, stage 3
8.1
27.2
38
51
103
Kela drug reimbursment
Diabetes, insulin-treated
3.1
26.8
192
920
B01AB10
ATC
tinzaparin; parenteral
4.0
26.2
86
253
L04AX01
ATC
azathioprine; systemic
7.0
26.2
42
66
A10AE04
ATC
insulin glargine; parenteral
3.9
26.1
90
274
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
53.8
25.6
30
6
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
3.7
25.4
96
311
TK820
NOMESCO Finland
Peritoneal dialysis
62.2
25.3
29
5
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.1
25.3
145
609
WX203
NOMESCO Finland
Infraclavicular plexus blockade
10.3
25.3
29
30
J01FF01
ATC
clindamycin; systemic
3.0
25.1
161
721
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
46.1
24.9
30
7
I50.1
ICD-10 Finland
Left ventricular failure
4.9
24.8
59
135
A10AB05
ATC
insulin aspart; parenteral
4.2
24.4
73
200
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
5.2
24.4
54
116
ZXD05
NOMESCO Finland
Urgent procedure
2.9
24.2
171
804
Z3231
NOMESCO Finland
Registered nurse
2.9
24.0
169
792
N25.0
ICD-10 Finland
Renal osteodystrophy
132.8
23.9
25
*
C02CA01
ATC
prazosin; oral
8.5
23.3
31
39
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
5.0
23.2
54
121
C10AA05
ATC
atorvastatin; oral
2.9
23.0
258
1533
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
88.6
22.9
25
*
SPAT1262
SPAT
Handing over of treatment supplies
3.1
22.7
124
502
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.9
22.6
152
691
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.9
22.5
77
232
D64.9
ICD-10 Finland
Anaemia, unspecified
3.4
22.4
98
347
J01DB01
ATC
cefalexin; oral
5.2
22.4
373
2766
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.8
21.9
174
862
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.3
21.5
102
379
WW200
NOMESCO Finland
Immunization
7.5
21.5
32
46
S97
ICPC
Chronic ulcer skin
4.0
21.4
67
189
JN4AD
NOMESCO Finland
Body CT examination
3.4
21.4
94
333
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
7.1
21.2
33
50
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
+∞
21.0
20
*
R60.0
ICD-10 Finland
Localized oedema
3.3
21.0
94
337
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.7
20.9
165
810
A12BA01
ATC
potassium chloride; oral
5.3
20.9
45
94
3025
Kela drug reimbursment
Calcium carbonate
32.0
20.8
27
9
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
50.8
20.4
24
5
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
8.4
20.3
27
34
3AC01, ,
NOMESCO Finland
24.9
20.2
28
12
J01MA02
ATC
ciprofloxacin; systemic
2.6
20.2
222
1278
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
4.0
19.9
63
179
TK810
NOMESCO Finland
Hemofiltration
30.7
19.9
26
9
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
110.5
19.7
21
*
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
17.9
19.5
30
18
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.7
19.5
68
207
A02BC02
ATC
pantoprazole; systemic
3.1
19.4
327
2307
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
3.2
19.4
95
358
R06.0
ICD-10 Finland
Dyspnoea
2.6
19.2
165
839
A41.9
ICD-10 Finland
Sepsis, unspecified
5.4
19.0
39
78
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
29.5
18.9
25
9
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.3
18.9
40
82
L28
ICPC
Limited function/disability (L)
2.8
18.8
129
584
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.0
18.7
99
390
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
5.2
18.7
40
83
A10AB01
ATC
insulin (human); parenteral
6.0
18.5
34
61
207
Kela drug reimbursment
Chronic arrhythmias
2.8
18.4
119
522
C10AA01
ATC
simvastatin; oral
2.6
18.4
254
1603
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
6.1
18.4
33
58
J01MA14
ATC
moxifloxacin; systemic
3.6
18.3
69
221
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.5
18.2
173
918
B01AC04
ATC
clopidogrel; oral
2.7
18.1
131
609
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
6.1
17.9
32
56
Z2446
NOMESCO Finland
Social worker
4.4
17.7
48
121
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
99.5
17.7
19
*
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.5
17.4
162
847
WX892
NOMESCO Finland
Monitored bed care
3.6
17.4
63
196
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
4.6
17.3
43
101
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
17.3
142
699
ZXE10
NOMESCO Finland
More than one and less than three hours
2.4
17.0
186
1044
H05BX02
ATC
paricalcitol; systemic
+∞
16.8
16
*
PG5AC
NOMESCO Finland
Contrast examination of injection gate to artery or vein
+∞
16.8
16
*
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
5.4
16.8
34
67
TPH07
NOMESCO Finland
Cathetrisation of artery
3.0
16.8
85
325
L17
ICPC
Foot/toe symptom/complaint
2.5
16.8
159
836
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.4
16.7
217
1312
A12AA12
ATC
[U] calcium acetate
94.0
16.7
18
*
KBV00
NOMESCO Finland
Insertion of stent into ureter
29.0
16.7
22
8
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
29.0
16.7
22
8
WW500
NOMESCO Finland
Blood transfusion
4.7
16.3
40
93
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.5
16.3
62
199
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.2
16.0
46
121
B99
ICD-10 Finland
Other and unspecified infectious diseases
6.7
16.0
26
41
WX882
NOMESCO Finland
High dependency care
6.2
15.9
28
48
N18
ICD-10 Finland
Chronic kidney disease
13.7
15.9
27
21
Z3226
NOMESCO Finland
Physiotherapist
2.7
15.9
105
462
PB1DE
NOMESCO Finland
Upper extremity arteries ultrasound examination with Doppler method
34.9
15.9
20
6
C01DA14
ATC
isosorbide mononitrate; oral
2.6
15.9
120
565
E66.00
ICD-10 Finland
Metabolic syndrome
4.3
15.7
43
109
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.4
15.7
157
841
A10AE05
ATC
insulin detemir; parenteral
4.2
15.4
43
111
A10AB04
ATC
insulin lispro; parenteral
6.4
15.3
26
43
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
5.7
15.2
29
54
R11
ICD-10 Finland
Nausea and vomiting
3.5
15.2
56
176
N02AX02
ATC
tramadol; systemic, rectal
2.3
14.9
221
1391
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
59.0
14.9
17
*
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.5
14.9
56
178
E86
ICD-10 Finland
Volume depletion
5.5
14.6
29
56
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
4.4
14.5
38
93
C03DA01
ATC
spironolactone; oral
2.8
14.5
88
369
A10AA01, ,
ATC
6.7
14.2
23
36
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
44.2
14.2
17
*
A10BB12
ATC
glimepiride; oral
3.2
14.1
62
217
AN1
HP
Coronary angiography
2.7
14.1
87
368
ZXA05
NOMESCO Finland
Left side
2.4
13.9
138
729
K07
ICPC
Swollen ankles/oedema
4.0
13.8
42
115
A10AA02, ,
ATC
5.2
13.8
29
59
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
5.1
13.8
30
63
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
+∞
13.6
13
*
PBU84
NOMESCO Finland
Plastic repair of arteriovenous fistula from artery of upper extremity
144.6
13.5
14
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.9
13.5
42
117
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
26.8
13.5
18
7
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.6
13.4
33
77
R60.9
ICD-10 Finland
Oedema, unspecified
3.9
13.4
42
118
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.1
13.3
60
213
M79.6
ICD-10 Finland
Pain in limb
2.2
13.3
194
1197
WZC30
NOMESCO Finland
Teaching
2.5
13.3
97
445
T90
ICPC
Diabetes non-insulin dependent
2.3
13.2
148
820
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.9
13.2
67
255
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.4
13.1
113
559
Z2221
NOMESCO Finland
Medical doctor
2.3
13.1
133
707
B01AF02
ATC
apixaban; oral
2.6
13.1
94
428
E66.8
ICD-10 Finland
Other obesity
5.0
13.0
29
62
C07AB02
ATC
metoprolol; systemic
2.3
12.9
123
636
K65.0
ICD-10 Finland
Acute peritonitis
14.7
12.9
21
15
E0000UV, ,
ATC
2.2
12.9
185
1131
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
4.9
12.8
29
63
RD210, ,
NOMESCO Finland
12.8
12.8
22
18
A07AA09
ATC
vancomycin; oral
16.1
12.7
20
13
N04.1
ICD-10 Finland
Nephrotic syndrome, focal and segmental glomerular lesions
72.2
12.7
14
*
Q61.3
ICD-10 Finland
Polycystic kidney, unspecified
33.2
12.7
16
5
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
3.8
12.6
40
113
I42.0
ICD-10 Finland
Dilated cardiomyopathy
4.8
12.6
29
64
RS220, ,
NOMESCO Finland
20.8
12.6
18
9
N03.0
ICD-10 Finland
Chronic nephritic syndrome, minor glomerular abnormality
+∞
12.6
12
*
ZXA00
NOMESCO Finland
Right side
2.2
12.6
146
819
AA1AD
NOMESCO Finland
CT of head and brain
2.2
12.5
168
997
D89.80
ICD-10 Finland
Immunoglobulin A (IgA) deposits in organisms
134.0
12.5
13
*
NHQ40
NOMESCO Finland
Amputation of toe
6.1
12.4
22
38
H02AB07
ATC
prednisone; oral
2.7
12.4
75
313
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.5
12.1
92
429
I50
ICD-10 Finland
Heart failure
4.4
12.0
31
75
J01MA12
ATC
levofloxacin; systemic
2.3
11.9
114
588
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
4.7
11.6
27
60
D638, N189,
ICD-10 Finland
123.4
11.5
12
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.5
11.4
85
391
C08DB01
ATC
diltiazem; oral
3.5
11.4
41
126
WX202
NOMESCO Finland
Supraclavicular plexus blockade
11.0
11.4
21
20
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.1
11.4
176
1094
A28
ICPC
Limited function/disability NOS
2.2
11.1
119
642
ZXE20
NOMESCO Finland
More than three and less than five hours
2.5
11.0
83
384
R02
ICPC
Shortness of breath/dyspnoea
2.5
11.0
77
344
E21.1
ICD-10 Finland
Secondary hyperparathyroidism, not elsewhere classified
44.6
11.0
13
*
A10BH01
ATC
sitagliptin; oral
2.7
10.9
66
274
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
4.5
10.9
27
63
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.1
10.9
162
988
SAA03
NOMESCO Finland
Extended examination of mouth
2.1
10.8
159
967
KBV10
NOMESCO Finland
Removal of stent from ureter
22.2
10.8
15
7
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
5.5
10.7
21
40
N08.2
ICD-10 Finland
Glomerular disorders in blood diseases and disorders involving the immune mechanism
61.7
10.7
12
*
B01AB05
ATC
enoxaparin; parenteral
2.1
10.7
158
961
SPAT1255
SPAT
Intravenous administration of medicine
3.2
10.6
44
148
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.2
10.5
108
571
N03.3
ICD-10 Finland
Chronic nephritic syndrome, diffuse mesangial proliferative glomerulonephritis
112.8
10.5
11
*
L04AA05
ATC
[U] tacrolimus
112.8
10.5
11
*
Z99.2
ICD-10 Finland
Dependence on renal dialysis
112.8
10.5
11
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.6
10.4
36
108
D63.8
ICD-10 Finland
Anaemia in other chronic diseases classified elsewhere
33.5
10.4
13
*
H43.1
ICD-10 Finland
Vitreous haemorrhage
4.7
10.4
24
53
R80
ICD-10 Finland
Isolated proteinuria
19.4
10.3
15
8
M01AB01
ATC
indometacin; systemic, rectal
2.9
10.3
52
196
WX204
NOMESCO Finland
Axillary plexus blockaced
4.3
10.3
27
66
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.8
10.3
57
226
A08
ICPC
Swelling
3.3
10.3
41
135
S18
ICPC
Laceration/cut
2.0
10.1
225
1570
E66.01
ICD-10 Finland
Obesity due to excess calories
3.3
10.1
40
131
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.0
10.0
188
1236
WZC00
NOMESCO Finland
Treatment plan or consultation
2.0
10.0
162
1012
XCK10
NOMESCO Finland
Photography of fundus of eye
2.6
10.0
62
261
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.3
10.0
40
132
WVA20
NOMESCO Finland
Medicine administration
4.2
9.9
27
68
N17.8
ICD-10 Finland
Other acute renal failure
9.1
9.9
20
23
A10BH02
ATC
vildagliptin; oral
5.1
9.9
21
43
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
9.9
94
480
H3603, E103,
ICD-10 Finland
26.8
9.9
13
5
C10AX09
ATC
ezetimibe; oral
2.2
9.8
100
525
GD1AD
NOMESCO Finland
Thorax CT examination
3.0
9.8
45
161
PD4AC
NOMESCO Finland
Arterigography of lower extremity with X-ray
5.5
9.7
19
36
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.5
9.7
71
323
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
4.6
9.7
23
52
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
4.3
9.6
25
61
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
9.6
170
1093
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
4.4
9.5
24
57
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.2
9.5
97
509
C09BA02
ATC
enalapril and diuretics; systemic
2.7
9.5
54
217
PB1BC
NOMESCO Finland
Extensive angiography of upper extremity with X-ray
102.3
9.5
10
*
58209
ICD-8 Finland
Chronic nephritis, Unspecified
102.3
9.5
10
*
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
102.3
9.5
10
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
5.3
9.4
19
37
N11.8
ICD-10 Finland
Other chronic tubulo-interstitial nephritis
+∞
9.4
9
*
V03AE04
ATC
calcium acetate and magnesium carbonate; systemic
+∞
9.4
9
*
I25.2
ICD-10 Finland
Old myocardial infarction
2.7
9.3
54
219
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.2
9.3
88
447
C03AA03
ATC
hydrochlorothiazide; oral
2.7
9.3
53
213
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.5
9.3
65
289
I21.41
ICD-10 Finland
Acute subendocardial infarction stenosed coronary artery
3.1
9.3
40
138
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
3.1
9.2
41
144
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
4.6
9.2
22
50
A41.8
ICD-10 Finland
Other specified sepsis
5.0
9.2
20
42
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.5
9.1
63
279
N02BE01
ATC
paracetamol; systemic, rectal
3.0
9.1
373
3204
306
Kela drug reimbursment
Erythropoietin and darbepoetin
37.6
9.1
11
*
K65.9
ICD-10 Finland
Peritonitis, unspecified
37.6
9.1
11
*
B07.9
ICD-10 Finland
Verruca simplex
4.4
9.0
23
55
WX002
NOMESCO Finland
Sedation and analgesia
2.1
9.0
99
534
SPAT1254
SPAT
Administration of medicine
2.3
9.0
78
382
WX722
NOMESCO Finland
PEEP
3.2
9.0
37
124
UJF32
NOMESCO Finland
Coloscopy
2.0
8.9
133
802
C09CA06
ATC
candesartan; oral
2.0
8.9
113
643
XF600
NOMESCO Finland
Bloodpressure measurement
2.9
8.8
43
159
K77
ICPC
Heart failure
4.4
8.8
22
52
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.6
8.7
53
220
C02EA02, ,
ATC
3.3
8.7
34
110
XF404
NOMESCO Finland
Ambulatory ECG
2.6
8.7
56
239
K78
ICPC
Atrial fibrillation/flutter
2.6
8.7
55
233
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
3.2
8.7
35
116
L30.3
ICD-10 Finland
Infective dermatitis
4.2
8.6
23
57
R53
ICD-10 Finland
Malaise and fatigue
2.0
8.6
123
730
TK830
NOMESCO Finland
Ultrafiltration
91.9
8.4
9
*
XX_20
NOMESCO Finland
Bioimpedance measurement
91.9
8.4
9
*
PG1XE
NOMESCO Finland
Other ultrasound examination of blood vessel not elsewhere classified
13.1
8.4
14
11
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.9
8.4
149
948
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.3
8.4
32
102
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.4
8.4
31
97
KAS40
NOMESCO Finland
Excision of transplanted kidney
+∞
8.4
8
*
XF602
NOMESCO Finland
Bloodpressure monitoring
9.7
8.3
16
17
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.6
8.3
49
201
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
4.1
8.3
23
59
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.8
8.2
44
171
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
4.5
8.2
20
46
S76
ICPC
Skin infection other
3.2
8.2
33
109
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.9
8.2
24
64
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.1
8.2
35
120
A10BK01
ATC
dapagliflozin; oral
2.6
8.2
48
196
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
8.1
106
607
E21.2
ICD-10 Finland
Other hyperparathyroidism
34.1
8.1
10
*
R04.0
ICD-10 Finland
Epistaxis
2.6
8.1
49
203
TPH05
NOMESCO Finland
Open cannulation of peripheral vein
10.3
8.1
15
15
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
4.0
8.1
23
60
201
Kela drug reimbursment
Chronic cardiac insufficiency
2.8
8.1
42
161
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.8
8.1
43
167
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
7.5
8.0
18
25
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
8.0
76
385
R31
ICD-10 Finland
Unspecified haematuria
2.2
8.0
76
385
ZY010
NOMESCO Finland
Hospital outpatient
3.9
8.0
24
65
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.7
8.0
25
70
XG466
NOMESCO Finland
Sleep oxymetry
3.7
8.0
25
70
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.7
8.0
25
70
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.7
8.0
45
180
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.2
7.9
70
345
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.5
7.9
55
244
I20.09
ICD-10 Finland
Unstable angina
2.7
7.9
45
181
K92.1
ICD-10 Finland
Melaena
2.9
7.9
38
140
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
7.8
178
1219
E66.9
ICD-10 Finland
Obesity, unspecified
4.5
7.8
19
44
WX610
NOMESCO Finland
Patient controlled analgesia
15.4
7.8
12
8
7151
FHL
Kidney transplantation
45.9
7.7
9
*
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
45.9
7.7
9
*
N03.8
ICD-10 Finland
Chronic nephritic syndrome, other
45.9
7.7
9
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.5
7.7
50
214
I48.1
ICD-10 Finland
Persistent atrial fibrillation
3.3
7.7
30
97
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.1
7.7
32
108
N03AX16
ATC
[U] pregabalin
2.0
7.7
102
587
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
3.5
7.7
26
77
C08CA05
ATC
nifedipine; systemic
2.8
7.7
38
142
UJF30
NOMESCO Finland
Ileoscopy through colon
2.4
7.6
54
241
N02AA05
ATC
oxycodone; systemic
2.0
7.6
106
619
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
6.4
7.6
19
31
ZXE00
NOMESCO Finland
One hour or less
1.8
7.6
162
1086
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
2.6
7.6
46
191
AN4
HP
Balloon angioplasty and drug eluding stent
3.4
7.5
27
83
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
6.2
7.5
19
32
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
7.9
7.5
16
21
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.6
7.5
43
174
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.7
7.4
40
156
T86.1
ICD-10 Finland
Kidney transplant failure and rejection
81.5
7.4
8
*
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
13.7
7.4
12
9
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.4
7.4
55
251
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
1.9
7.4
118
721
58200
ICD-8 Finland
Chronic nephritis, Cum uraemia
+∞
7.3
7
*
JAF30
NOMESCO Finland
Repair of umbilical hernia using prosthetic material
6.0
7.3
19
33
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.1
7.3
81
436
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.2
7.3
67
335
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.7
7.3
40
158
C09AA05
ATC
ramipril; oral
1.8
7.3
141
916
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
16.1
7.3
11
7
PE1YT
NOMESCO Finland
Femoral or popliteal artery PTA with stent
7.5
7.3
16
22
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.7
7.2
23
65
WX402
NOMESCO Finland
General anaesthesia
2.0
7.2
95
543
D02AE01
ATC
carbamide; topical
3.0
7.2
33
118
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.4
7.2
51
228
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.9
7.2
21
56
FM1LE
NOMESCO Finland
Combined ultrasound and EKG examination of heart with tolerance test
20.4
7.2
10
5
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.5
7.2
48
209
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
4.2
7.2
19
47
A10BG03
ATC
pioglitazone; oral
4.2
7.2
19
47
J01CF05
ATC
flucloxacillin; systemic
2.7
7.1
39
154
C09DA01
ATC
losartan and diuretics; oral
2.3
7.1
57
270
H25.1
ICD-10 Finland
Senile nuclear cataract
1.8
7.0
155
1044
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
3.2
7.0
28
92
C03BA11
ATC
indapamide; oral
4.5
7.0
17
39
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
2.9
7.0
33
120
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.8
7.0
132
849
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
4.1
7.0
19
48
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.8
6.9
127
809
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
8.5
6.9
14
17
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.3
6.9
54
253
WX872
NOMESCO Finland
Intensive care
2.8
6.8
35
133
SPAT1099
SPAT
Measurement of blood pressure with Doppler ultrasound device
3.3
6.8
25
78
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.4
6.8
17
40
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.9
6.8
110
673
ZST00
NOMESCO Finland
Procedure related to previous procedure classified in chapter T
40.7
6.8
8
*
K99
ICPC
Cardiovascular disease other
3.8
6.7
20
54
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
2.5
6.7
45
196
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.2
6.7
57
276
R5140
NOMESCO Finland
Monitoring the use of the aid
2.2
6.7
62
311
B01AB04
ATC
dalteparin; parenteral
3.1
6.7
28
95
J01DA01
ATC
[U] cefalexin
1.7
6.7
246
1906
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
12.5
6.6
11
9
A10BJ02
ATC
liraglutide; parenteral
3.9
6.6
19
50
C10AA04
ATC
fluvastatin; oral
2.2
6.6
56
271
I44.2
ICD-10 Finland
Atrioventricular block, complete
3.1
6.5
27
91
M25.5
ICD-10 Finland
Pain in joint
1.8
6.5
122
781
Z94.1
ICD-10 Finland
Heart transplant status
70.9
6.4
7
*
187
Kela drug reimbursment
MPA
70.9
6.4
7
*
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
4.2
6.4
17
42
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.8
6.4
32
120
SPAT1263
SPAT
Sampling
1.7
6.4
168
1182
ZXA10
NOMESCO Finland
Bilateral
1.9
6.4
91
533
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
3.3
6.4
24
76
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
5.3
6.4
18
35
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
2.7
6.4
34
132
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.7
6.4
35
138
AN3
HP
Balloon angioplasty and metallic stent
3.4
6.4
23
71
R58
ICD-10 Finland
Haemorrhage, not elsewhere classified
5.7
6.4
17
31
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
11.3
6.3
11
10
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
2.2
6.3
54
262
C01AA05
ATC
digoxin; systemic
2.3
6.3
50
235
C08CA03
ATC
isradipine; systemic
7.2
6.3
14
20
A10BB01
ATC
glibenclamide; oral
2.9
6.3
30
110
PBU99
NOMESCO Finland
Other repair after previous reconstruction of arteries of upper extremity
+∞
6.3
6
*
I12
ICD-10 Finland
Hypertensive renal disease
+∞
6.3
6
*
5850B
ICD-9 Finland
Chronic renal failure[INSUFFICIENTIA RENIS CHRONICA CUM URAEMIA]
+∞
6.3
6
*
5829A
ICD-9 Finland
Chronic glomerulonephritis with unspecified pathological lesion in kidney[GLOMERULONEPHRITIS CHRONICA NUD ,EI NEFR SDR]
+∞
6.3
6
*
BBA50
NOMESCO Finland
Total parathyroidectomy
+∞
6.3
6
*
Q61.0
ICD-10 Finland
Congenital single renal cyst
+∞
6.3
6
*
N05.9
ICD-10 Finland
Unspecified nephritic syndrome, unspecified
27.1
6.2
8
*
N03.1
ICD-10 Finland
Chronic nephritic syndrome, focal and segmental glomerular lesions
27.1
6.2
8
*
I77.0
ICD-10 Finland
Arteriovenous fistula, acquired
27.1
6.2
8
*
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.0
6.2
71
385
SPAT1104
SPAT
Monitoring of emergency patient
2.6
6.2
35
140
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
5.9
6.2
16
28
CKC12
NOMESCO Finland
Photocoagulation of retina
3.0
6.2
27
94
A10AD05
ATC
insulin aspart; parenteral
3.9
6.2
18
48
SPAT1211
SPAT
Application of soft bandage
2.4
6.1
43
191
TQW11
NOMESCO Finland
Vacuum treatment of wound
4.2
6.1
16
39
KAC11
NOMESCO Finland
Total nephrectomy with capsule, transcutaneous
12.8
6.1
10
8
PF1BT
NOMESCO Finland
Extensive PTA of arteries of knee, lower leg and ankle
10.2
6.1
11
11
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
2.0
6.1
67
359
SPAT1229
SPAT
Assessment of need for aid
2.5
6.1
40
173

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
299
370
27.69
262.49
28.6
6.7
16.95
10.78
mmol/l
25.06
289
353
264
284
24.61
251.09
13.7
3.7
193.84
86.47
ng/l
16.09
242
248
311
549
20.78
205.69
29.4
5.5
1.21
1.02
mmol/l
16.62
302
510
348
957
19.19
150.36
9.5
2.8
429.37
359.80
umol/l
19.45
337
838
222
414
10.60
130.50
15.7
3.7
0.76
1.68
mmol/l
2.58
203
349
226
432
10.51
129.98
15.4
3.7
7.36
7.38
ph
5.45
179
250
124
109
15.92
126.02
7.7
2.5
2.61
1.57
mg/l
15.70
112
101
191
364
9.00
107.43
17.1
9.5
—
—
—
0
0
142
212
9.75
97.74
2.2
2.0
1.71
1.47
g/l
1.83
133
193
181
358
8.30
97.25
10.9
2.9
5.83
4.42
kpa
5.57
176
345
79
65
14.84
82.04
13.5
2.7
21.37
9.58
pmol/l
5.04
79
65
48
11
49.34
81.51
2.3
1.5
—
—
—
0
0
206
571
6.28
75.79
3.2
2.0
—
—
—
0
0
220
665
6.02
72.90
6.2
3.3
0.81
0.82
mmol/l
0.75
212
627
318
1347
7.22
70.70
11.1
4.1
37.22
8.81
mg/mmol
8.44
294
868
293
1196
6.18
66.62
9.3
4.5
—
—
—
0
0
66
57
13.63
66.14
2.7
1.4
161.33
145.17
au/ml
0.30
23
14
70
68
12.22
65.06
2.5
1.4
—
—
—
0
0
52
31
19.08
63.64
1.1
1.3
—
—
—
0
0
299
1292
5.95
61.97
10.4
3.8
35.08
110.69
e6/l
0.85
276
999
147
356
5.90
61.08
3.2
3.1
64.02
65.96
g/l
1.91
139
328
300
1314
5.88
60.73
9.1
3.4
195.80
54.35
mg/l
6.41
275
882
303
1339
5.94
60.65
9.1
3.3
6.08
7.94
mmol/l
19.23
291
1118
344
1708
7.55
59.55
21.1
5.3
33.87
34.89
g/l
3.23
339
1599
240
900
5.06
58.39
7.9
2.9
4.03
4.11
e6/l
0.03
234
825
75
93
9.66
58.31
1.8
1.6
13649.74
12787.96
e6/l
0.07
57
71
65
68
11.19
57.23
1.7
1.1
304.20
299.07
u/ml
0.02
54
29
153
411
5.36
55.92
4.1
1.7
—
—
—
0
0
54
44
14.00
55.80
2.1
2.4
1.03
1.24
g/24h
0.19
38
25
314
1492
5.83
55.67
11.0
3.0
267.20
163.54
ug/l
8.43
307
1379
266
1118
4.98
54.91
9.5
3.6
0.29
0.45
e6/l
0.93
239
830
314
1504
5.76
54.76
5.4
2.4
75.98
77.64
nmol/l
0.49
307
1337
302
1403
5.47
54.71
12.3
4.5
44.09
144.04
e6/l
1.26
276
1031
92
159
7.18
53.60
2.6
4.6
55.15
52.93
mg/l
0.06
76
139
173
531
4.93
53.42
4.3
2.8
2.10
1.81
%
2.57
163
482
128
306
5.64
53.26
9.7
3.2
7.39
7.42
ph
6.51
118
259
139
360
5.35
52.69
4.3
1.5
—
—
—
0
0
265
1138
4.81
52.44
23.1
4.4
7.38
7.40
ph
5.37
234
825
91
159
7.08
52.41
2.6
4.6
77.23
98.44
mg/l
0.24
74
137
66
85
9.07
49.54
1.7
1.2
—
—
—
0
0
146
414
4.94
49.25
4.7
2.9
70.60
68.06
e9/l
0.38
107
323
127
321
5.30
49.22
4.5
1.6
—
—
—
0
0
190
666
4.48
48.61
6.9
3.4
1.64
1.16
e6/l
0.63
124
355
152
450
4.80
48.49
2.7
1.8
—
—
—
0
0
347
1919
6.48
47.61
45.3
7.4
1.21
1.21
mmol/l
0.45
328
1663
64
85
8.75
46.78
8.6
2.9
—
—
—
0
0
82
147
6.73
45.78
2.7
4.1
1.75
2.87
ratio
0.91
43
82
320
1732
4.97
43.03
32.4
6.8
1.22
1.21
mmol/l
1.64
312
1595
189
710
4.10
42.93
6.0
3.2
0.78
1.05
e6/l
0.62
124
398
54
67
9.14
41.55
1.8
1.6
—
—
—
0
0
111
301
4.70
38.70
2.6
2.8
—
—
—
0
0
223
1005
3.70
37.45
3.8
2.3
3.14
2.96
mg/l
0.54
209
873
315
1800
4.32
36.38
12.0
6.2
0.68
0.62
e9/l
3.80
284
1518
119
356
4.31
36.31
8.0
2.7
0.25
0.51
e6/l
0.51
119
346
33
24
14.88
36.05
1.2
1.1
—
—
—
0
0
315
1810
4.28
35.84
12.1
6.2
0.04
0.04
e9/l
0.51
287
1533
39
38
11.24
35.65
5.0
2.0
9.89
11.11
%
0.80
39
38
316
1836
4.23
34.97
12.1
6.3
1.57
1.85
e9/l
3.40
286
1599
69
136
5.91
34.59
1.5
1.3
—
—
—
0
0
324
1927
4.34
34.36
45.1
16.1
1.44
1.31
inr
2.82
292
1616
297
1670
3.88
34.19
12.7
6.2
3.13
2.91
%
0.70
291
1570
246
1229
3.53
34.17
11.2
6.0
—
—
—
0
0
297
1672
3.87
34.08
12.8
6.2
0.53
0.65
%
3.51
292
1570
297
1673
3.87
34.02
12.8
6.3
9.26
9.19
%
0.16
292
1571
299
1701
3.86
33.52
12.7
6.4
20.88
25.73
%
13.72
294
1614
315
1860
4.07
33.22
12.5
6.4
0.23
0.20
e9/l
1.87
286
1604
255
1340
3.42
31.86
5.9
3.3
6907.45
1623.39
ng/l
10.70
243
1166
37
8
50.70
31.16
7.3
5.3
—
—
—
0
0
33
33
10.79
29.53
1.5
1.3
38226.15
182913.04
e6/l
0.78
20
24
122
425
3.67
29.35
1.6
1.3
476.67
406.24
titre
0.24
24
109
319
1989
3.79
28.91
14.7
10.0
5.01
4.29
e9/l
6.29
293
1726
54
100
6.07
28.72
4.8
2.2
122.19
125.87
g/l
0.40
48
79
33
7
51.13
27.88
15.4
9.1
5.46
5.97
mmol/l
—
33
7
136
524
3.40
27.76
8.7
7.8
5.00
5.11
kpa
0.56
127
502
341
2249
4.18
27.70
15.1
5.4
7.65
6.88
mmol/l
5.66
335
2157
136
525
3.39
27.66
8.6
7.8
10.46
11.59
kpa
2.34
126
505
216
1093
3.08
27.56
4.9
3.5
—
—
—
0
0
134
514
3.40
27.52
8.4
7.9
-0.32
0.74
mmol/l
1.40
109
432
353
2394
4.58
27.29
14.1
4.7
—
2.94
—
0
7
133
519
3.32
26.43
8.9
7.9
7.42
7.41
ph
0.13
69
301
165
733
3.10
26.26
2.4
1.7
1162.66
1179.22
nmol/l
0.06
149
562
288
1742
3.23
26.23
3.2
2.3
96.43
94.19
pmol/l
0.32
173
942
33
39
9.12
26.12
1.5
1.6
73.71
60.20
%
1.18
27
30
125
477
3.34
25.68
8.8
7.9
93.85
94.94
%
0.78
117
463
226
1211
2.95
25.36
4.8
2.7
—
—
—
0
0
97
317
3.70
25.36
7.5
4.5
1.01
0.93
%
0.12
47
113
93
298
3.75
25.01
7.7
4.6
0.07
0.12
%
0.33
43
94
256
1475
2.98
24.96
7.6
3.8
6.44
6.19
ph
2.58
139
841
60
139
4.89
24.81
8.4
2.9
378.96
275.35
mg/l
0.85
48
62
230
1255
2.91
24.76
7.5
3.5
2.35
2.34
mmol/l
0.16
223
1128
341
2325
3.88
24.58
9.4
5.0
1130.00
1005.85
e6/l
—
5
47
28
29
10.29
24.37
1.4
1.4
20.20
32.85
%
0.93
23
21
75
213
4.09
23.88
10.5
3.4
—
—
—
0
0
120
471
3.19
23.26
1.3
1.3
7.21
12.15
u/ml
0.32
41
181
182
902
2.84
23.11
4.7
2.8
—
—
—
0
0
291
1854
3.00
22.55
10.2
4.2
16.35
4.12
estimate
0.33
84
395
288
1831
2.96
22.28
10.2
4.2
0.00
0.00
estimate
-0.00
82
380
90
304
3.52
22.17
7.1
4.3
0.66
0.56
%
0.29
41
107
31
14
23.85
22.04
3.0
1.7
0.60
0.63
mmol/l
0.50
31
14
291
1867
2.96
22.00
10.2
4.2
0.00
0.83
estimate
0.51
79
365
55
134
4.59
21.30
3.0
1.6
—
—
—
0
0
267
1656
2.78
21.22
5.0
3.0
—
—
estimate
—
0
0
51
118
4.80
21.03
2.6
2.1
3.73
7.58
iu/ml
—
10
32
366
2725
4.41
20.69
23.2
8.7
93.52
80.94
u/l
2.59
358
2575
26
8
34.58
20.44
1.0
1.3
—
—
—
0
0
26
8
34.58
20.44
1.0
1.0
—
—
—
0
0
211
1190
2.61
19.94
2.5
1.8
20.33
20.16
nmol/l
0.05
200
1001
46
102
4.96
19.93
3.9
2.4
275.13
77.39
ug/min
0.90
32
56
88
314
3.30
19.71
7.9
4.7
0.00
0.20
%
1.29
37
93
249
1530
2.62
19.52
33.6
12.1
0.00
0.00
e9/l
0.57
204
1237
35
62
6.08
19.33
1.4
1.3
23.73
28.60
g/l
1.19
29
56
107
435
2.98
19.13
10.1
8.4
112.92
120.11
g/l
2.69
101
426
47
110
4.70
19.08
8.8
3.6
1.46
1.68
mmol/l
1.08
47
105
32
53
6.47
18.87
1.4
1.2
19409.23
27384.52
e6/l
0.24
26
31
209
1201
2.52
18.60
2.4
2.2
130.89
299.26
u/l
1.91
203
1142
67
210
3.62
18.32
2.6
1.5
—
—
—
0
0
52
139
4.14
17.79
1.9
2.0
22.83
21.02
s
1.43
46
132
21
5
44.08
17.45
1.0
1.0
—
—
—
0
0
41
93
4.79
17.25
9.0
3.8
7.57
7.70
mmol/l
0.13
41
88
34
66
5.53
17.05
2.0
1.2
—
—
—
0
0
114
510
2.72
16.80
1.4
1.3
28.38
30.59
iu/ml
0.11
39
165
56
165
3.78
16.71
2.2
2.1
297.97
575.45
ug/l
0.53
56
159
150
781
2.46
16.02
2.7
1.7
1.47
1.62
mg/l
0.27
128
619
148
777
2.42
15.41
8.0
4.2
74.43
435.84
ng/l
3.60
139
672
88
364
2.81
14.93
3.8
2.8
7.02
8.18
ug/l
0.22
82
325
34
75
4.86
14.76
6.8
3.4
1.93
2.11
mmol/l
0.13
18
45
135
693
2.42
14.66
8.7
5.4
—
—
—
0
0
76
296
2.93
14.38
10.1
9.5
1.29
1.31
%
0.05
70
291
68
253
3.03
13.94
11.2
9.5
14.58
15.67
%
2.02
62
242
40
106
4.08
13.79
1.3
1.6
—
—
—
0
0
236
1562
2.22
13.66
7.4
4.3
120.72
49.68
ng/l
1.23
208
1243
63
228
3.09
13.53
1.7
1.8
0.89
1.65
g/l
1.73
63
207
81
339
2.73
13.35
4.6
2.6
43.26
34.91
u/l
1.08
74
286
23
19
12.75
13.26
5.0
1.7
233.09
75.17
ng/l
1.21
23
19
80
336
2.72
13.08
1.9
2.2
338.26
385.19
nmol/l
1.09
74
313
25
47
5.60
12.93
1.3
3.1
—
—
—
0
0
70
277
2.84
12.80
6.1
4.4
—
—
—
0
0
187
1167
2.11
12.15
4.5
3.5
43.75
35.35
u/l
0.35
179
1106
24
47
5.36
11.88
1.3
1.1
—
—
—
0
0
25
52
5.06
11.58
1.8
1.5
—
—
—
0
0
25
52
5.06
11.58
1.8
1.5
—
—
—
0
0
25
52
5.06
11.58
1.8
1.5
—
—
—
0
0
25
52
5.06
11.58
1.8
1.5
—
—
—
0
0
170
1068
2.02
10.44
13.6
6.3
—
—
—
0
0
47
167
3.05
10.36
1.4
1.3
—
—
—
0
0
20
22
9.50
10.13
4.3
2.9
515.80
504.64
min
0.22
20
14
76
356
2.40
9.75
5.1
2.2
0.00
0.00
estimate
-0.00
25
73
371
3154
2.99
9.69
15.7
7.2
44.58
40.42
mmol/mol
7.94
363
2936
21
44
4.98
9.64
1.5
1.1
—
—
—
0
0
36
116
3.31
9.31
6.1
5.1
—
—
—
0
0
48
185
2.81
9.14
5.1
2.5
0.00
4.39
estimate
0.49
16
57
377
3260
3.12
8.99
70.5
18.8
30.16
27.54
mg/l
0.91
368
2773
21
47
4.66
8.94
1.4
1.5
—
—
—
0
0
19
39
5.06
8.92
1.1
1.2
—
—
—
0
0
131
786
1.98
8.90
4.6
3.2
2.51
2.46
mmol/l
3.68
117
703
35
115
3.24
8.78
6.6
3.3
4.10
1.52
index
0.52
21
67
302
2392
2.02
8.73
4.7
3.9
14.83
15.02
pmol/l
0.67
289
2153
50
202
2.68
8.70
11.6
4.0
1.02
1.02
ratio
5.04
50
189
77
381
2.26
8.65
2.8
2.5
0.22
0.20
g/l
1.18
71
354
19
26
7.61
8.54
1.2
1.3
76.32
98.58
pmol/l
1.24
19
26
61
274
2.44
8.54
10.9
6.1
23.77
24.33
mmol/l
0.52
55
261
153
981
1.90
8.46
10.5
3.7
0.30
0.09
estimate
0.30
66
303
358
3059
2.41
8.00
8.1
4.6
1.70
1.28
mmol/l
12.81
341
2783
160
1060
1.84
7.85
10.3
4.2
0.00
0.01
estimate
0.74
66
348
196
1386
1.80
7.72
10.6
4.2
0.00
0.03
estimate
1.47
68
320
142
913
1.85
7.63
1.5
1.3
—
—
—
0
0
104
608
1.95
7.45
1.6
1.5
2.97
2.82
g/l
0.23
78
370
66
327
2.22
7.35
1.7
1.4
—
—
—
0
0
83
450
2.06
7.34
2.1
1.4
—
—
—
0
0
21
56
3.90
7.17
2.0
2.3
32.86
32.77
pg
0.04
21
56
19
48
4.10
6.97
1.5
1.3
2.00
7.42
u/ml
—
10
24
29
99
3.08
6.84
1.8
1.5
272.00
283.14
ug/g
0.12
20
60
26
83
3.28
6.84
1.4
1.2
—
—
—
0
0
347
2979
2.12
6.82
6.3
4.9
2.33
1.98
mu/l
3.52
331
2696
85
479
1.98
6.71
1.2
1.3
—
—
—
0
0
364
3206
2.28
6.33
9.1
5.5
3.98
4.37
mmol/l
11.85
349
2960
12
13
9.47
6.33
1.2
1.0
43.83
38.40
g/l
—
6
6
182
1313
1.70
6.30
3.0
2.2
—
—
—
0
0
362
3183
2.24
6.29
9.0
5.4
1.22
1.39
mmol/l
12.45
347
2920
13
17
7.86
6.17
1.5
1.7
—
—
—
0
0
368
3273
2.30
5.95
9.7
6.3
2.11
2.53
mmol/l
20.94
353
3007
123
809
1.75
5.88
1.9
1.9
469.48
23788311.27
pmol/l
0.69
113
660
17
36
4.88
5.67
1.2
1.3
—
—
—
0
0
11
13
8.66
5.59
1.1
1.0
1533.45
1514.23
miu/ml
0.01
11
13
262
2121
1.66
5.53
6.0
3.5
89.04
57.06
u/l
2.15
252
1983
36
155
2.45
5.51
1.4
1.2
—
—
—
0
0
18
53
3.51
5.37
5.2
2.2
3.84
4.50
e9/l
0.62
18
53
183
1368
1.61
5.24
7.0
4.1
—
0.60
—
0
5
5
0
+∞
5.22
3.2
0.0
1.11
—
g/l
—
5
0
12
19
6.47
5.11
1.2
1.2
176.67
181.03
mmol/24h
0.04
12
19
369
3335
2.14
4.91
59.9
16.7
—
—
—
0
0
16
47
3.50
4.79
3.9
3.8
—
—
—
0
0
80
491
1.78
4.77
1.5
1.3
—
—
—
0
0
15
36
4.29
4.56
2.1
2.4
—
—
—
0
0
14
32
4.49
4.48
1.0
1.1
—
—
—
0
0
8
9
9.04
4.29
2.8
1.4
5.10
8.14
mmol/l
—
8
9
13
29
4.60
4.28
1.2
1.9
—
—
—
0
0
37
182
2.14
4.20
3.1
2.5
—
—
—
0
0
40
203
2.08
4.19
2.5
3.1
—
—
—
0
0
8
10
8.13
4.07
3.9
5.4
62.66
44.85
%
—
8
10
22
87
2.62
4.03
1.5
1.2
—
—
—
0
0
16
55
2.99
3.78
2.1
3.1
—
—
—
0
0
10
21
4.85
3.57
1.1
1.4
—
—
—
0
0
7
9
7.89
3.57
1.4
1.2
—
—
—
0
0
59
361
1.74
3.54
29.3
4.2
7.35
7.35
ph
0.14
53
271
13
36
3.70
3.52
1.6
1.3
—
—
—
0
0
94
652
1.57
3.47
1.3
1.3
1.75
1.42
u/ml
0.17
25
175
6
7
8.68
3.27
1.0
1.4
—
—
—
0
0
69
452
1.63
3.21
2.6
3.1
5.54
4.78
e9/l
0.55
58
391
18
76
2.43
2.93
6.5
2.4
57.11
58.32
%
0.17
18
76
6
9
6.75
2.87
1.0
1.6
—
—
—
0
0
15
59
2.60
2.82
1.2
1.1
—
—
—
0
0
10
29
3.51
2.71
1.1
1.2
—
—
—
0
0
10
31
3.28
2.53
1.1
1.2
—
—
—
0
0
59
395
1.58
2.52
1.4
1.3
—
—
—
0
0
26
137
1.96
2.52
1.5
1.5
0.20
0.37
mg/l
1.03
13
62
5
8
6.31
2.38
1.4
1.0
421.80
178.18
iu/ml
—
5
8
15
66
2.32
2.27
2.5
2.5
—
—
—
0
0
7
18
3.94
2.26
1.0
1.1
—
—
—
0
0
5
9
5.61
2.22
23.2
8.8
6.21
6.46
kpa
—
5
9
5
9
5.61
2.22
1.2
1.4
26.60
29.33
%
—
5
9
5
9
5.61
2.22
23.4
9.0
6.68
4.68
kpa
—
5
9
7
19
3.73
2.16
3.3
1.8
1240.57
1000.16
u/ml
—
7
19
9
31
2.95
2.08
1.4
1.1
—
—
—
0
0
9
31
2.95
2.08
1.4
1.1
—
—
—
0
0
41
264
1.61
2.08
16.3
4.1
—
—
—
0
0
5
10
5.05
2.07
3.0
1.1
1.14
1.19
mmol/l
—
5
10
6
15
4.04
2.04
1.7
2.5
—
—
—
0
0
6
15
4.04
2.04
2.0
1.5
—
—
—
0
0
105
821
1.38
2.04
8.4
4.5
1.02
1.02
kg/l
4.70
85
567
8
26
3.12
2.02
2.9
2.5
—
—
—
0
0
8
27
3.00
1.94
10.5
3.3
0.88
0.96
index
—
8
27
30
182
1.70
1.91
1.1
1.3
—
51.62
—
0
17
7
23
3.08
1.80
1.1
1.9
56.03
36.13
%
—
7
23
8
29
2.79
1.80
1.3
1.1
—
—
—
0
0
21
118
1.82
1.73
1.7
1.6
12.32
11.04
u/ml
—
5
20
31
196
1.63
1.71
1.3
1.2
—
—
—
0
0
340
3194
1.39
1.70
9.6
5.6
6.66
6.11
mmol/l
6.73
325
2906
8
31
2.61
1.66
1.5
1.2
—
—
—
0
0
10
41
2.47
1.65
1.3
1.1
—
—
—
0
0
224
1993
1.28
1.65
5.1
5.9
2.24
2.63
ug/l
0.62
212
1792
32
207
1.59
1.62
2.2
2.5
—
15.01
—
0
12
23
136
1.73
1.62
1.1
1.2
21.47
98.12
u/ml
—
7
43
5
14
3.60
1.62
1.0
1.2
6.02
7.77
mmol/l
—
5
14
5
15
3.36
1.53
1.4
1.7
—
—
—
0
0
5
15
3.36
1.53
18.6
9.0
21.18
26.16
mmol/l
—
5
15
5
15
3.36
1.53
1.0
1.1
—
—
—
0
0
59
441
1.40
1.50
2.9
4.6
3.59
41.22
ug/l
1.35
51
376
10
45
2.25
1.47
5.7
1.8
13.32
10.42
mmol/l
—
10
45
6
22
2.75
1.44
1.2
1.8
41.33
39.30
g/l
—
6
22
40
281
1.47
1.42
6.0
3.0
6.08
6.01
ph
0.17
32
200
32
217
1.52
1.35
1.2
1.2
—
—
—
0
0
8
34
2.38
1.30
2.0
1.6
14.63
15.72
%
—
8
34
11
55
2.03
1.28
1.0
1.2
1.69
1.50
g/l
0.79
11
49
26
173
1.54
1.21
3.4
1.9
—
—
—
0
0
15
87
1.75
1.16
1.3
1.9
—
—
—
0
0
8
39
2.07
1.16
1.1
1.3
—
—
nmol/l
—
0
0
8
39
2.07
1.16
10.8
3.4
10.38
11.63
index
—
8
27
5
20
2.52
1.15
1.0
1.7
229.20
87.65
umol/l
—
5
20
11
58
1.92
1.13
1.2
1.1
—
—
—
0
0
7
33
2.14
1.06
2.0
1.5
12.04
8.95
mmol/l
—
7
33
7
33
2.14
1.06
1.1
1.3
—
—
—
0
0
5
22
2.29
1.03
1.2
1.2
—
—
—
0
0
7
35
2.02
1.00
1.3
1.1
—
—
—
0
0
9
51
1.78
0.95
1.0
1.2
—
—
—
0
0
8
42
1.92
0.89
1.1
1.3
—
—
—
0
0
8
43
1.88
0.87
1.6
1.3
—
—
—
0
0
8
43
1.88
0.87
1.0
1.3
—
—
—
0
0
6
30
2.01
0.87
3.0
2.2
—
—
—
0
0
8
45
1.79
0.84
1.1
1.2
—
—
—
0
0
8
45
1.79
0.84
1.1
1.2
—
—
—
0
0
153
1379
1.18
0.83
2.4
2.0
1.78
1.31
mmol/l
6.74
143
1141
8
46
1.75
0.83
1.1
1.2
—
—
—
0
0
12
73
1.66
0.82
1.3
1.3
39.83
1662.86
e6/l
0.54
12
58
19
131
1.47
0.80
1.7
1.9
43.37
44.20
nmol/l
0.05
19
123
0
26
0.00
0.78
0.0
1.1
—
3.07
—
0
12
7
38
1.86
0.74
3.6
2.5
—
—
—
0
0
5
93
0.53
0.67
1.2
1.1
—
—
—
0
0
5
29
1.73
0.64
2.6
1.4
—
—
—
0
0
5
29
1.73
0.64
1.2
1.2
—
—
—
0
0
5
29
1.73
0.64
3.4
2.3
1.84
1.89
ug/l
—
5
22
18
130
1.40
0.62
1.1
1.1
—
—
—
0
0
5
30
1.67
0.61
3.6
1.2
—
—
—
0
0
41
338
1.24
0.59
1.3
1.4
—
—
—
0
0
6
35
1.72
0.58
1.5
1.3
22.17
32.23
ng/l
—
6
35
9
128
0.70
0.44
1.1
1.1
—
—
—
0
0
8
58
1.39
0.41
1.1
1.3
—
—
—
0
0
8
61
1.32
0.39
1.0
1.2
—
—
—
0
0
8
114
0.70
0.37
37.9
14.6
—
—
—
0
0
5
37
1.36
0.37
1.0
1.1
—
17.50
—
0
11
10
76
1.32
0.28
1.1
1.1
—
—
—
0
0
37
330
1.13
0.26
1.7
1.5
—
—
—
0
0
125
1194
1.07
0.22
3.4
3.3
0.99
0.79
ug/l
1.14
101
815
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
15.2
—
1000.50
—
0
12
0
13
0.00
0.21
0.0
1.0
—
3.98
—
0
6
10
123
0.81
0.20
2.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
117
1126
1.05
0.16
6.5
3.5
—
—
—
0
0
5
44
1.14
0.10
4.4
2.9
5.40
6.78
nmol/l
—
5
44
6
58
1.03
0.08
1.2
1.4
—
—
—
0
0
7
68
1.03
0.08
1.1
1.7
—
3.46
—
0
28
18
177
1.02
0.00
1.4
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
14.11
—
0
7
0
6
0.00
-0.00
0.0
2.7
—
106.50
—
0
6
0
6
0.00
-0.00
0.0
2.5
—
7.39
—
0
6
0
9
0.00
-0.00
0.0
10.1
—
0.64
—
0
9
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
69
1.01
-0.00
2.9
1.2
1.00
0.88
g/l
—
7
69
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
53.33
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.8
—
2.17
—
0
6
0
8
0.00
-0.00
0.0
2.1
—
9635.38
—
0
8
0
5
0.00
-0.00
0.0
1.6
—
0.70
—
0
5
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint GOUT_KIDNEY and mortality.

Females

Parameter HR [95% CI] p-value
GOUT_KIDNEY 3.249 [2.27, 4.66] < 0.001
Birth year 0.991 [0.98, 1.0] 0.047

During the follow-up period (1.1.1998 — 31.12.2019), 269 out of 519 females with GOUT_KIDNEY died.

Males

Parameter HR [95% CI] p-value
GOUT_KIDNEY 3.409 [2.41, 4.82] < 0.001
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 471 out of 1000 males with GOUT_KIDNEY died.

Mortality risk

Mortality risk for people of age

years, who have GOUT_KIDNEY.

N-year risk Females Males
1 0.325% 0.617%
5 1.813% 4.031%
10 4.542% 9.412%
15 8.29% 17.3%
20 14.068% 28.218%

Relationships between endpoints

Index endpoint: GOUT_KIDNEY – Gout due to impairment of renal function

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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