pyelonephritis: Inflammation of the KIDNEY involving the renal parenchyma (the NEPHRONS); KIDNEY PELVIS; and KIDNEY CALICES. It is characterized by ABDOMINAL PAIN; FEVER; NAUSEA; VOMITING; and occasionally DIARRHEA.
Renal tubulo-interstitial disorders in diseases classified elsewhere
DOID EFO Endpoint Browser PheWeb
N14_RENALTUBULOINOTH
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
404 |
4. Check minimum number of eventsNone |
404 |
5. Include endpointsNone |
404 |
6. Filter based on genotype QC (FinnGen only) |
349 |
Control definitions (FinnGen only)
- Control exclude
- N14_RENALTUB
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Renal tubulo-interstitial disorders in diseases classified elsewhere
based on the number of shared cases.
Similar with more cases:
- All chronic kidney diseases
- Renal tubulo-interstitial diseases
- All kidney diseases
- Genitourinary diseases
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1856 | 880 | 962 |
| Only index persons | 1584 | 749 | 835 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.03 | 0.03 |
| Only index persons | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 62.48 | 63.34 | 61.63 |
| Only index persons | 62.08 | 62.77 | 61.46 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 349 | 167 | 182 |
| Unadjusted period prevalence (%) | 0.07 | 0.06 | 0.08 |
| Median age at first event (years) | 59.41 | 57.07 | 61.55 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 363
- Matched controls
- 3630
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
172.1
316.3
157
16
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
109.0
162.4
84
10
L04AA06
ATC
mycophenolic acid; systemic
88.6
144.8
77
11
N19
ICD-10 Finland
Unspecified kidney failure
48.6
133.5
80
21
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
34.5
122.2
81
30
N16.2*D86.8
ICD-10 Finland
Renal tubulo-interstitial disorders in sarcoidosis
+∞
120.7
109
*
B03XA02
ATC
darbepoetin alfa; parenteral
61.8
116.9
66
13
E83.50
ICD-10 Finland
Hypercalcemia
69.1
114.0
63
11
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
+∞
107.8
98
*
A11CC03
ATC
alfacalcidol; systemic
455.0
103.8
99
*
KA1AE
NOMESCO Finland
Kidney ultrasound examination
42.1
102.1
63
18
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
17.0
95.5
87
66
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
+∞
95.1
87
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
581.0
93.8
89
*
N18.8
ICD-10 Finland
Other chronic renal failure
227.8
87.5
87
5
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
13.7
84.5
88
83
M04AA01
ATC
allopurinol; systemic
8.7
83.6
139
242
L04AX01
ATC
azathioprine; systemic
15.8
78.3
73
57
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
8.1
77.3
136
250
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
11.0
76.6
94
112
C03CA01
ATC
furosemide; systemic
6.9
74.9
224
690
A12AA04
ATC
calcium carbonate; oral
441.5
74.6
72
*
TK800
NOMESCO Finland
Hemodialysis
185.1
73.1
74
5
D86.0
ICD-10 Finland
Sarcoidosis of lung
34.7
66.5
43
14
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
108.1
65.6
70
8
Z94.0
ICD-10 Finland
Kidney transplant status
+∞
64.5
60
*
Z49.1
ICD-10 Finland
Extracorporeal dialysis
713.1
62.8
60
*
127
Kela drug reimbursment
Transplant complication
98.8
60.3
65
8
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
+∞
56.8
53
*
N18.0
ICD-10 Finland
End-stage renal disease
+∞
56.8
53
*
L04AD01
ATC
ciclosporin; systemic
24.9
55.2
40
18
N16.3*E83.50
ICD-10 Finland
Nefrocalcinosis NEC
+∞
54.6
51
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.3
52.2
286
1350
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
9.4
51.6
68
87
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
295.6
51.5
51
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
5.0
51.4
211
789
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.6
50.4
98
193
TPX10
NOMESCO Finland
Implantation of vascular injection port
14.0
49.7
48
39
M10.9
ICD-10 Finland
Gout, unspecified
7.5
48.2
79
130
Z49.0
ICD-10 Finland
Preparatory care for dialysis
+∞
48.0
45
*
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
+∞
48.0
45
*
137
Kela drug reimbursment
Uraemia requiring dialysis
+∞
48.0
45
*
205
Kela drug reimbursment
Chronic hypertension
4.6
45.2
172
595
H02AB04
ATC
methylprednisolone; systemic
5.3
45.0
119
308
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
+∞
42.5
40
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
7.9
42.2
64
96
L04AD02
ATC
tacrolimus; systemic
102.5
41.8
45
5
B05DA
ATC
Isotonic solutions
+∞
40.4
38
*
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
+∞
40.4
38
*
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
+∞
40.4
38
*
132
Kela drug reimbursment
Sarcoidosis
94.8
38.7
42
5
N16.1*C90.0
ICD-10 Finland
Renal tubulo-interstitial disorders in multiple myeloma
+∞
38.2
36
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.5
38.1
123
369
Z49.2
ICD-10 Finland
Other dialysis
+∞
37.1
35
*
ZX120
NOMESCO Finland
Intravenous
5.6
36.7
82
181
B05DB
ATC
Hypertonic solutions
+∞
35.0
33
*
M05BA04
ATC
alendronic acid; oral
5.8
34.5
72
149
C08CA01
ATC
amlodipine; oral
3.8
34.2
210
970
N16.3*M10.9
ICD-10 Finland
Gout nephropathy
+∞
33.9
32
*
V03AE01
ATC
polystyrene sulfonate; oral
128.7
33.3
35
*
M10.0
ICD-10 Finland
Idiopathic gout
9.5
32.9
41
48
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
5.4
32.8
75
168
Z2446
NOMESCO Finland
Social worker
6.5
32.6
59
106
JN3AD
NOMESCO Finland
Abdominal CT examination
4.6
32.2
92
248
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
10.7
31.7
36
37
A10AC01
ATC
insulin (human); parenteral
5.8
31.6
65
132
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
62.2
29.7
34
6
196
Kela drug reimbursment
Paricalcitol and cinacalcet
+∞
29.6
28
*
V03AE02
ATC
sevelamer; oral
+∞
29.6
28
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
8.1
29.5
42
58
L04AA01
ATC
[U] ciclosporin
48.2
29.3
35
8
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
7.0
29.0
47
75
N16.2
ICD-10 Finland
Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism
+∞
28.5
27
*
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
46.7
28.3
34
8
C08CA02
ATC
felodipine; oral
5.0
28.3
70
167
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
+∞
27.4
26
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.7
26.6
109
377
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
+∞
26.4
25
*
H02AB06
ATC
prednisolone; systemic
3.3
26.4
229
1245
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.7
26.3
108
374
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.4
25.7
75
203
D86.2
ICD-10 Finland
Sarcoidosis of lung with sarcoidosis of lymph nodes
32.8
25.5
33
11
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
+∞
25.3
24
*
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
9.8
25.1
30
33
GD1AD
NOMESCO Finland
Thorax CT examination
5.4
24.7
53
111
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
6.4
24.3
43
75
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
+∞
24.2
23
*
WW200
NOMESCO Finland
Immunization
9.8
24.2
29
32
H05BX01
ATC
cinacalcet; oral
133.8
23.9
25
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
8.2
23.7
33
44
B03XA01
ATC
erythropoietin; parenteral
50.3
23.7
28
6
JN4AD
NOMESCO Finland
Body CT examination
4.0
23.7
81
246
Z3231
NOMESCO Finland
Registered nurse
3.1
22.8
147
662
TPH04
NOMESCO Finland
Cathetrisation of vein
3.2
22.6
124
508
A10AB05
ATC
insulin aspart; parenteral
4.9
22.4
54
125
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
6.2
22.2
40
71
N16.5*T86.9
ICD-10 Finland
Renal tubulo-interstitial disorder in transplant rejection
+∞
22.1
21
*
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
7.3
22.1
34
51
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.1
21.9
69
197
A12BA01
ATC
potassium chloride; oral
7.1
21.7
34
52
XW000
NOMESCO Finland
Bone marrow biopsy
6.0
21.5
40
73
C90.0
ICD-10 Finland
Multiple myeloma
23.2
21.2
30
14
N18.3
ICD-10 Finland
Chronic kidney disease, stage 3
18.3
20.9
32
19
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.9
20.4
70
212
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.8
20.2
151
727
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.9
20.0
68
204
N16.4*M32.1
ICD-10 Finland
Renal tubulo-interstitial disorders in systemic lupus erythematosus
+∞
20.0
19
*
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
+∞
20.0
19
*
N16.4*M35.0
ICD-10 Finland
Sjögren's syndrome with renal tubulo-interstitial disorders
+∞
20.0
19
*
V03AE03
ATC
lanthanum carbonate; oral
+∞
20.0
19
*
ZX108
NOMESCO Finland
Inhalation
31.0
19.9
26
9
D64.9
ICD-10 Finland
Anaemia, unspecified
3.9
19.9
68
205
ZXD05
NOMESCO Finland
Urgent procedure
2.8
19.7
146
698
R50.9
ICD-10 Finland
Fever, unspecified
3.4
19.5
85
301
A41.9
ICD-10 Finland
Sepsis, unspecified
7.2
19.0
29
43
TK810
NOMESCO Finland
Hemofiltration
+∞
18.9
18
*
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
+∞
18.9
18
*
TK820
NOMESCO Finland
Peritoneal dialysis
+∞
18.9
18
*
N18.4
ICD-10 Finland
Chronic kidney disease, stage 4
199.9
18.7
19
*
J01FF01
ATC
clindamycin; systemic
2.8
18.6
137
650
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
6.4
18.1
31
52
C07AB07
ATC
bisoprolol; oral
2.7
18.0
223
1360
I50.9
ICD-10 Finland
Heart failure, unspecified
3.3
17.9
79
281
A12AA12
ATC
[U] calcium acetate
+∞
17.9
17
*
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
100.0
17.7
19
*
3AC01, ,
NOMESCO Finland
30.6
17.6
23
8
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
5.0
17.5
40
88
C09AA02
ATC
enalapril; systemic
2.9
17.4
103
433
J01MA12
ATC
levofloxacin; systemic
3.0
17.4
97
395
U14
ICPC
Kidney symptom/complaint
33.3
17.2
22
7
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
27.1
17.1
23
9
Z3226
NOMESCO Finland
Physiotherapist
2.9
17.1
99
411
J01MA02
ATC
ciprofloxacin; systemic
2.6
16.8
165
894
321
Kela drug reimbursment
Paricalcitol and cinacalcet
94.5
16.7
18
*
153
Kela drug reimbursment
Lenalidomid
29.1
16.7
22
8
L04AX04
ATC
lenalidomide; oral
29.1
16.7
22
8
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
6.5
16.6
28
46
N17.8
ICD-10 Finland
Other acute renal failure
177.8
16.6
17
*
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
42.2
16.5
20
5
R4110
NOMESCO Finland
Physiotherapy
2.6
16.1
138
698
C07AG02
ATC
carvedilol; oral
4.4
16.0
43
108
ZXE20
NOMESCO Finland
More than three and less than five hours
3.1
16.0
78
293
XF400
NOMESCO Finland
ECG with 12 standard connections
3.0
15.9
83
324
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.8
15.8
103
453
I50.0
ICD-10 Finland
Congestive heart failure
4.1
15.8
46
123
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
+∞
15.7
15
*
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
+∞
15.7
15
*
B01AB10
ATC
tinzaparin; parenteral
3.4
15.7
63
210
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
13.2
15.6
27
22
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
166.9
15.6
16
*
D86.1
ICD-10 Finland
Sarcoidosis of lymph nodes
33.3
15.0
19
6
A46
ICD-10 Finland
Erysipelas
3.0
14.9
78
304
Z2221
NOMESCO Finland
Medical doctor
2.5
14.9
130
658
M05BX04
ATC
denosumab; parenteral
4.3
14.9
41
105
K65.0
ICD-10 Finland
Acute peritonitis
22.2
14.8
21
10
T86.1
ICD-10 Finland
Kidney transplant failure and rejection
+∞
14.7
14
*
E87.5
ICD-10 Finland
Hyperkalaemia
13.3
14.6
25
20
N02AX02
ATC
tramadol; systemic, rectal
2.4
14.5
190
1151
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.5
14.4
122
607
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.0
14.4
72
273
A02BC02
ATC
pantoprazole; systemic
2.7
14.4
280
2019
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.6
14.2
51
158
H02AB07
ATC
prednisone; oral
3.0
14.2
75
294
R4190
NOMESCO Finland
Nutritional therapy
5.5
14.1
28
54
C02AC05
ATC
moxonidine; oral
4.8
14.1
33
74
C09CA01
ATC
losartan; oral
2.5
14.1
126
643
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
5.2
14.1
30
62
KBV00
NOMESCO Finland
Insertion of stent into ureter
55.6
13.9
16
*
J01MA14
ATC
moxifloxacin; systemic
3.4
13.9
54
176
XG410
NOMESCO Finland
Flow-volume spirometry
4.8
13.8
32
71
WX892
NOMESCO Finland
Monitored bed care
3.7
13.8
47
140
212
Kela drug reimbursment
Gout
11.6
13.7
25
23
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
+∞
13.6
13
*
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
+∞
13.6
13
*
3025
Kela drug reimbursment
Calcium carbonate
+∞
13.6
13
*
N16.3
ICD-10 Finland
Renal tubulo-interstitial disorders in metabolic diseases
+∞
13.6
13
*
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
+∞
13.6
13
*
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.9
13.5
43
122
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
145.2
13.5
14
*
TPH07
NOMESCO Finland
Cathetrisation of artery
3.1
13.5
62
224
A10BH05
ATC
linagliptin; oral
4.6
13.4
33
77
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.6
13.3
48
149
SPAT1262
SPAT
Handing over of treatment supplies
2.8
13.3
81
342
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.4
13.2
119
606
WX002
NOMESCO Finland
Sedation and analgesia
2.6
13.2
98
456
ZXE00
NOMESCO Finland
One hour or less
2.3
13.2
166
977
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
17.5
13.1
20
12
A07AA09
ATC
vancomycin; oral
17.5
13.1
20
12
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.9
13.1
41
115
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
5.6
13.0
25
47
A10AE04
ATC
insulin glargine; parenteral
3.3
13.0
55
189
I12.0
ICD-10 Finland
Hypertensive renal disease with renal failure
52.0
12.9
15
*
RD210, ,
NOMESCO Finland
14.8
12.9
21
15
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
4.6
12.7
31
72
N16.3*M10.0
ICD-10 Finland
Nephropathy caused by gout
+∞
12.6
12
*
N25.0
ICD-10 Finland
Renal osteodystrophy
+∞
12.6
12
*
N16.0*A02.2
ICD-10 Finland
Salmonella renal tubulo-interstitial disease
+∞
12.6
12
*
B01AA03
ATC
warfarin; systemic
2.6
12.6
90
411
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
134.5
12.5
13
*
A10AE05
ATC
insulin detemir; parenteral
4.3
12.5
34
86
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.8
12.2
39
111
S97
ICPC
Chronic ulcer skin
3.6
12.2
43
131
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
6.1
11.9
21
36
C10AA05
ATC
atorvastatin; oral
2.2
11.8
185
1176
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
13.2
11.8
20
16
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
9.1
11.7
24
28
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
19.7
11.7
17
9
329
Kela drug reimbursment
Lenalidomide
23.8
11.7
16
7
KH1AD
NOMESCO Finland
CT of urinary organs
5.3
11.6
24
48
WX402
NOMESCO Finland
General anaesthesia
2.4
11.6
99
489
WX872
NOMESCO Finland
Intensive care
3.9
11.5
35
96
N17.0
ICD-10 Finland
Acute renal failure with tubular necrosis
+∞
11.5
11
*
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
+∞
11.5
11
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
3.2
11.5
48
163
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
123.8
11.5
12
*
WW400
NOMESCO Finland
Plasmaferesis
123.8
11.5
12
*
WZC00
NOMESCO Finland
Treatment plan or consultation
2.2
11.5
155
926
M01AE01
ATC
ibuprofen; systemic, rectal
0.4
11.5
236
2929
J01DB01
ATC
cefalexin; oral
2.9
11.4
315
2513
E86
ICD-10 Finland
Volume depletion
8.5
11.3
24
30
H02AB09
ATC
hydrocortisone; systemic
8.5
11.3
24
30
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
5.5
11.2
22
42
C07AB02
ATC
metoprolol; systemic
2.4
11.2
89
425
XF600
NOMESCO Finland
Bloodpressure measurement
3.7
11.0
36
104
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.1
11.0
170
1066
WX610
NOMESCO Finland
Patient controlled analgesia
44.8
11.0
13
*
P01BA02
ATC
hydroxychloroquine; oral
3.2
10.6
45
154
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.9
10.6
56
218
ZST00
NOMESCO Finland
Procedure related to previous procedure classified in chapter T
+∞
10.5
10
*
KAS40
NOMESCO Finland
Excision of transplanted kidney
+∞
10.5
10
*
N11.8
ICD-10 Finland
Other chronic tubulo-interstitial nephritis
+∞
10.5
10
*
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
+∞
10.5
10
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.1
10.4
140
828
B07.9
ICD-10 Finland
Verruca simplex
4.9
10.4
23
49
ZXA00
NOMESCO Finland
Right side
2.2
10.4
116
639
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.7
10.3
62
258
C08CA13
ATC
lercanidipine; oral
2.5
10.3
73
330
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
8.8
10.2
21
25
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
9.6
10.1
20
22
TGC00
NOMESCO Finland
Bronchial lavation
5.0
10.1
22
46
RS220, ,
NOMESCO Finland
15.1
10.1
16
11
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
10.0
111
607
D86
ICD-10 Finland
Sarcoidosis
41.3
10.0
12
*
N02AA05
ATC
oxycodone; systemic
2.4
10.0
85
417
E87.6
ICD-10 Finland
Hypokalaemia
4.6
10.0
24
55
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
10.0
147
898
ZXA05
NOMESCO Finland
Left side
2.2
9.9
106
572
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
26.9
9.9
13
5
RS221, ,
NOMESCO Finland
13.9
9.8
16
12
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.5
9.7
24
56
WX2DD
NOMESCO Finland
Low-dose CT of skeleton in whole body
56.5
9.7
11
*
C02EA02, ,
ATC
4.2
9.7
26
65
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.4
9.6
36
114
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.9
9.6
48
181
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.4
9.5
72
335
GD2SN
NOMESCO Finland
Lung ventilation SPECT
30.9
9.5
12
*
103
Kela drug reimbursment
Diabetes, insulin-treated
2.1
9.4
115
651
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.2
9.4
40
137
H05BX02
ATC
paricalcitol; systemic
+∞
9.4
9
*
PG5AC
NOMESCO Finland
Contrast examination of injection gate to artery or vein
+∞
9.4
9
*
N165, T861,
ICD-10 Finland
+∞
9.4
9
*
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
4.0
9.4
27
71
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
9.0
9.4
19
22
WX204
NOMESCO Finland
Axillary plexus blockaced
4.3
9.4
25
62
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
9.9
9.4
18
19
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.5
9.3
65
290
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.4
9.3
24
58
A02BC01
ATC
omeprazole; systemic
2.1
9.2
115
657
M10
ICD-10 Finland
Gout
3.9
9.2
28
77
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
5.0
9.2
20
42
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
16.1
9.1
14
9
RS222, ,
NOMESCO Finland
16.1
9.1
14
9
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.7
9.0
52
211
R11
ICD-10 Finland
Nausea and vomiting
2.9
8.9
45
170
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.6
8.9
56
238
A06AD11
ATC
lactulose; oral
2.5
8.9
62
277
UJF32
NOMESCO Finland
Coloscopy
2.1
8.8
110
626
AA1AD
NOMESCO Finland
CT of head and brain
2.0
8.8
122
722
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
6.9
8.8
21
32
I10
ICD-10 Finland
Essential (primary) hypertension
2.0
8.7
238
1774
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
16.8
8.6
13
8
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
16.8
8.6
13
8
H26.3
ICD-10 Finland
Drug-induced cataract
16.8
8.6
13
8
T89
ICPC
Diabetes insulin dependent
3.9
8.6
26
71
WW500
NOMESCO Finland
Blood transfusion
3.9
8.6
26
71
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
4.1
8.6
24
62
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.5
8.5
61
275
I41.8*D86.8
ICD-10 Finland
Sarcoid myocarditis
28.3
8.5
11
*
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.1
8.5
104
587
EBA15
NOMESCO Finland
Extraction of multiple teeth
4.2
8.5
23
58
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
92.1
8.4
9
*
E21.2
ICD-10 Finland
Other hyperparathyroidism
92.1
8.4
9
*
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
13.2
8.4
14
11
WX720
NOMESCO Finland
Own respiration
3.6
8.4
28
82
A04AA01
ATC
ondansetron; systemic, rectal
2.8
8.4
44
170
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
+∞
8.4
8
*
N16.0
ICD-10 Finland
Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere
+∞
8.4
8
*
UKC02
NOMESCO Finland
Cystoscopy
2.3
8.3
68
326
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.0
8.3
39
142
B01AB04
ATC
dalteparin; parenteral
3.6
8.3
28
83
L03AA02
ATC
filgrastim; parenteral
4.5
8.3
20
46
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
4.9
8.2
18
38
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
8.2
94
517
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
7.1
8.2
19
28
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
17.7
8.1
12
7
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.9
8.1
41
155
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
3.0
7.9
37
134
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.7
7.8
25
71
J01EA01
ATC
trimethoprim; systemic
2.1
7.8
92
510
N18
ICD-10 Finland
Chronic kidney disease
15.5
7.8
12
8
A28
ICPC
Limited function/disability NOS
2.2
7.8
75
385
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
46.0
7.7
9
*
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.4
7.7
28
87
N03AX16
ATC
[U] pregabalin
2.1
7.7
93
521
N12
ICD-10 Finland
Tubulo-interstitial nephritis, not specified as acute or chronic
25.6
7.6
10
*
KBV10
NOMESCO Finland
Removal of stent from ureter
25.6
7.6
10
*
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
10.3
7.6
14
14
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
7.5
87
478
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.5
7.5
48
205
A41.8
ICD-10 Finland
Other specified sepsis
7.9
7.5
16
21
TJW99
NOMESCO Finland
Other minor procedure in gastrointestinal endoscopy
81.7
7.4
8
*
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
81.7
7.4
8
*
SPAT1255
SPAT
Intravenous administration of medicine
3.1
7.4
31
105
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.8
7.4
38
145
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.0
7.4
98
566
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.5
7.4
26
79
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.7
7.4
40
157
UJF30
NOMESCO Finland
Ileoscopy through colon
2.5
7.3
50
220
V03AE04
ATC
calcium acetate and magnesium carbonate; systemic
+∞
7.3
7
*
K65.9
ICD-10 Finland
Peritonitis, unspecified
+∞
7.3
7
*
5901A
ICD-9 Finland
Infections of kidney, Acute pyelonephritis
+∞
7.3
7
*
187
Kela drug reimbursment
MPA
+∞
7.3
7
*
A12AA06
ATC
calcium lactate gluconate; oral
+∞
7.3
7
*
TK830
NOMESCO Finland
Ultrafiltration
+∞
7.3
7
*
Z99.2
ICD-10 Finland
Dependence on renal dialysis
+∞
7.3
7
*
XCK10
NOMESCO Finland
Photography of fundus of eye
2.6
7.3
45
189
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.9
7.3
114
697
A10AB01
ATC
insulin (human); parenteral
3.9
7.2
21
56
NHQ40
NOMESCO Finland
Amputation of toe
8.2
7.2
15
19
PG1XE
NOMESCO Finland
Other ultrasound examination of blood vessel not elsewhere classified
20.5
7.2
10
5
E83.51
ICD-10 Finland
Hypocalcemia
20.5
7.2
10
5
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.4
7.1
26
81
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.2
7.1
29
97
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
4.4
7.1
18
43
N20.1
ICD-10 Finland
Calculus of ureter
4.0
7.1
20
52
C08CA05
ATC
nifedipine; systemic
3.0
7.0
31
109
A07AA02
ATC
nystatin; oral
3.2
6.9
28
93
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.9
6.9
100
594
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
8.5
6.9
14
17
201
Kela drug reimbursment
Chronic cardiac insufficiency
3.0
6.8
30
105
M81.4
ICD-10 Finland
Drug-induced osteoporosis
40.8
6.8
8
*
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.2
6.8
27
89
ZXD20
NOMESCO Finland
Day surgery
2.3
6.7
54
256
R80
ICD-10 Finland
Isolated proteinuria
23.0
6.7
9
*
GD1UN
NOMESCO Finland
Lung circulation SPECT
23.0
6.7
9
*
NF1AA
NOMESCO Finland
Hip X-ray examination
2.5
6.7
43
184
WX882
NOMESCO Finland
High dependency care
6.1
6.7
17
29
OAB50, ,
SPAT
2.7
6.7
38
153
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
2.9
6.7
31
112
L28
ICPC
Limited function/disability (L)
2.1
6.6
74
401
R06.0
ICD-10 Finland
Dyspnoea
1.9
6.5
109
677
M13.9
ICD-10 Finland
Arthritis, unspecified
2.7
6.5
37
149
C10AA01
ATC
simvastatin; oral
1.8
6.5
161
1128
Y83.0
ICD-10 Finland
Surgical operation with transplant of whole organ as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
71.1
6.4
7
*
1350A
ICD-9 Finland
Sarcoidosis[SARCOIDOSIS]
71.1
6.4
7
*
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
14.6
6.4
10
7
I50
ICD-10 Finland
Heart failure
4.2
6.4
17
42
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
5.4
6.4
18
35
S01BA04
ATC
prednisolone; ophthalmic
6.1
6.4
16
27
H25.1
ICD-10 Finland
Senile nuclear cataract
1.9
6.4
109
682
N05CF01
ATC
zopiclone; oral
1.8
6.3
122
791
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
4.0
6.3
18
47
58199
ICD-8 Finland
Nephrotic syndrome
+∞
6.3
6
*
N03.8
ICD-10 Finland
Chronic nephritic syndrome, other
+∞
6.3
6
*
PBU84
NOMESCO Finland
Plastic repair of arteriovenous fistula from artery of upper extremity
+∞
6.3
6
*
N16.3*E72.0
ICD-10 Finland
Renal tubulo-interstitial disorders in cystinosis
+∞
6.3
6
*
7151
FHL
Kidney transplantation
+∞
6.3
6
*
N04.1
ICD-10 Finland
Nephrotic syndrome, focal and segmental glomerular lesions
+∞
6.3
6
*
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
+∞
6.3
6
*
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
+∞
6.3
6
*
G05.8*M32.1
ICD-10 Finland
Encephalitis in systemic lupus erythematosus
+∞
6.3
6
*
6BA02, ,
NOMESCO Finland
27.2
6.3
8
*
288
Kela drug reimbursment
Febuxostat
27.2
6.3
8
*
K29.3
ICD-10 Finland
Chronic superficial gastritis
3.7
6.2
20
57
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
3.4
6.2
22
67
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.9
6.2
88
518
C02CA01
ATC
prazosin; oral
7.9
6.2
13
17
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.3
6.1
23
73
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
12.8
6.1
10
8
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
8.8
6.1
12
14
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.0
6.1
72
397
E0000UV, ,
ATC
1.7
6.1
155
1088
WX203
NOMESCO Finland
Infraclavicular plexus blockade
5.4
6.1
17
33
TKC20
NOMESCO Finland
Catheterisation of bladder
2.8
6.1
30
112
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
222
183
29.66
247.88
10.7
1.9
128.83
65.29
ng/l
10.07
200
162
268
349
26.52
226.72
22.9
3.0
1.12
0.97
mmol/l
9.95
263
317
98
40
33.19
143.84
3.9
1.8
4.58
5.33
mmol/24h
0.49
93
35
70
29
29.67
101.04
3.1
2.4
1.33
1.64
g/24h
0.18
56
16
196
439
8.53
94.81
7.9
2.0
22.27
23.57
%
0.72
190
404
93
83
14.72
92.81
9.9
4.4
457.88
38.84
mg/l
0.67
75
71
93
83
14.72
92.81
9.9
4.4
80.20
26.78
mg/l
0.86
76
71
88
77
14.77
88.71
9.6
3.7
191.17
2.91
ratio
0.71
48
47
76
53
17.87
87.00
10.3
6.1
344.32
219.29
iu/ml
—
19
7
203
509
7.78
86.64
7.8
2.0
11.64
13.72
umol/l
4.48
198
470
143
271
8.06
79.24
14.5
2.2
0.89
2.24
mmol/l
3.61
122
236
238
792
6.82
72.51
7.0
2.7
401.85
340.60
umol/l
13.51
225
687
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
71
66
13.13
68.26
3.2
2.4
0.25
0.30
iu/ml
0.60
31
39
125
242
7.35
66.82
6.5
2.5
63.72
66.66
g/l
3.44
120
226
87
114
9.72
65.41
2.9
1.7
1.57
1.36
g/l
1.23
80
103
58
49
13.90
58.90
8.5
1.5
13.25
6.44
pmol/l
3.29
58
49
319
1594
9.26
56.43
41.7
5.8
1.22
1.21
mmol/l
1.72
296
1366
174
525
5.44
56.39
5.7
2.9
0.81
0.82
mmol/l
0.12
169
501
299
1427
7.21
55.05
31.9
5.2
1.23
1.21
mmol/l
3.29
293
1305
292
1373
6.76
54.45
19.4
4.6
34.53
35.83
g/l
3.66
285
1292
245
1005
5.42
53.69
10.5
2.9
18.77
119.37
e6/l
0.89
225
763
55
51
12.53
52.54
2.1
1.2
142.77
159.15
au/ml
0.31
13
16
110
235
6.28
52.18
9.8
2.3
4.82
4.45
kpa
1.20
105
228
247
1060
5.16
50.00
11.2
3.8
32.95
6.11
mg/mmol
3.57
220
628
286
1389
5.99
49.23
5.3
2.3
81.43
77.89
nmol/l
0.61
277
1238
87
157
6.97
48.72
7.6
2.6
0.64
2.11
mmol/l
3.02
65
118
41
26
17.65
48.49
1.1
1.1
—
—
—
0
0
96
195
6.33
47.69
8.5
2.4
4.87
5.16
kpa
3.78
91
188
245
1098
4.79
45.43
9.9
3.0
6.29
8.08
mmol/l
10.71
236
885
54
61
10.22
44.84
1.7
1.2
—
—
—
0
0
209
872
4.29
41.73
10.3
2.8
0.25
0.40
e6/l
0.47
186
632
88
187
5.89
41.32
9.6
7.2
23.50
24.97
mmol/l
2.77
88
187
51
60
9.73
40.99
1.8
1.2
244.23
321.94
u/ml
0.62
39
34
104
261
5.18
40.40
5.9
2.5
9.36
10.51
g/l
1.56
99
233
88
200
5.49
38.19
2.8
1.6
—
—
—
0
0
146
499
4.22
37.87
3.0
1.8
—
—
—
0
0
62
102
7.12
37.48
6.9
2.5
0.67
0.93
g/l
0.25
50
93
34
25
14.90
36.99
1.9
1.2
134.56
118.16
pmol/l
0.18
34
25
53
79
7.68
34.96
2.3
1.6
—
—
—
0
0
52
78
7.61
34.09
2.3
1.6
—
—
—
0
0
224
1082
3.79
34.01
8.7
3.4
2.35
2.35
mmol/l
0.37
215
973
119
376
4.22
33.92
2.8
1.7
—
—
—
0
0
147
540
3.89
33.82
7.5
2.6
0.65
0.76
e6/l
0.25
101
296
55
90
7.02
33.29
6.7
2.2
0.01
0.00
g/l
0.49
46
85
139
501
3.88
32.72
8.2
2.7
2.26
1.97
e6/l
0.17
93
260
52
88
6.73
30.40
6.5
2.2
0.00
0.00
g/l
-0.00
43
79
258
1447
3.71
29.41
7.9
2.8
184.56
124.37
ug/l
4.93
247
1332
292
1827
4.06
26.96
22.9
9.4
4.46
4.06
e9/l
1.67
273
1603
62
139
5.17
26.86
6.9
1.8
30.02
4.73
iu/ml
2.12
19
30
38
52
8.05
26.81
2.2
1.8
—
—
—
0
0
258
1522
3.40
25.51
25.9
13.8
1.30
1.25
inr
0.64
226
1253
170
799
3.12
24.85
3.0
2.1
3.19
2.95
mg/l
0.51
154
682
102
353
3.63
24.69
3.2
1.8
—
—
—
0
0
48
93
5.80
24.35
1.9
1.2
—
—
—
0
0
40
65
6.79
24.17
2.1
1.4
—
—
—
0
0
47
90
5.85
24.13
1.8
1.2
—
—
—
0
0
264
1612
3.34
23.94
9.2
3.5
0.00
0.00
estimate
0.50
66
346
35
50
7.64
23.75
1.2
1.2
—
—
—
0
0
266
1643
3.32
23.41
9.2
3.5
0.00
0.93
estimate
0.50
61
325
34
48
7.71
23.30
1.2
1.2
226.67
166.67
titre
—
6
6
264
1628
3.28
23.20
9.2
3.5
0.00
4.68
estimate
0.50
67
347
300
2000
3.88
23.13
10.2
4.0
349.71
223.13
e6/l
—
7
30
272
1716
3.33
22.79
10.9
6.5
10.16
11.77
umol/l
2.58
263
1632
81
256
3.79
22.27
7.2
2.2
0.33
0.20
e6/l
0.31
81
241
26
29
9.58
21.45
1.2
1.1
—
—
—
0
0
191
1023
2.83
21.06
4.7
3.1
3495.45
957.20
ng/l
6.46
176
868
35
57
6.69
21.05
1.7
1.4
—
—
—
0
0
330
2411
5.06
20.80
24.0
8.0
80.29
78.78
u/l
0.24
322
2266
29
40
7.79
20.22
1.6
1.2
—
—
—
0
0
19
0
+∞
19.98
13.0
0.0
4.83
—
mmol/l
—
19
0
28
38
7.90
19.78
2.3
1.6
—
—
—
0
0
109
445
3.07
19.68
12.1
6.5
103.09
104.27
mmol/l
1.30
109
445
31
20
16.82
19.65
1.7
1.8
1383.26
679.90
mg
0.97
31
20
25
30
8.88
19.49
2.2
2.2
—
—
—
0
0
30
45
7.18
19.44
1.8
1.5
—
—
—
0
0
26
33
8.41
19.39
2.2
2.1
—
—
—
0
0
35
62
6.14
19.38
1.4
1.7
—
—
—
0
0
28
39
7.70
19.35
1.6
1.5
—
—
—
0
0
280
1881
3.14
19.34
14.3
4.7
6.70
6.60
mmol/l
0.38
273
1782
60
171
4.01
18.96
2.0
1.6
—
—
—
0
0
85
309
3.29
18.59
5.4
3.0
—
—
—
0
0
36
73
5.36
17.27
4.0
2.0
128.10
129.65
g/l
0.10
29
55
31
56
5.96
16.79
2.0
1.4
—
—
—
0
0
179
1008
2.53
16.73
4.9
2.6
63.76
67.04
u/l
0.19
171
933
36
76
5.15
16.50
2.6
1.5
—
—
—
0
0
110
493
2.77
16.38
2.1
1.7
1166.85
1147.57
nmol/l
0.07
93
366
71
250
3.29
16.22
5.9
2.9
34.60
70.33
ml/min/173m2
15.23
45
103
47
127
4.10
15.88
2.7
2.0
5.15
3.30
ug/l
0.16
47
115
34
72
5.11
15.52
5.0
2.4
280.10
105.07
ug/min
0.89
29
39
180
1056
2.40
14.88
5.6
3.4
32.06
30.72
u/l
0.13
169
999
30
59
5.45
14.85
9.5
2.5
4.84
5.13
kpa
1.43
30
59
308
2344
3.07
14.00
11.2
4.2
20.03
11.12
mm/h
11.38
302
2162
86
365
2.78
14.00
8.2
7.6
-0.24
1.07
mmol/l
1.13
72
311
50
159
3.49
13.32
12.3
2.0
0.59
0.61
%
0.19
50
159
217
1426
2.30
13.23
2.8
2.1
104.03
98.89
pmol/l
0.68
134
723
143
790
2.34
13.21
3.9
2.4
—
—
—
0
0
17
6
29.61
13.07
2.8
4.0
0.59
0.60
mmol/l
—
17
6
49
156
3.48
13.03
1.8
1.3
—
—
—
0
0
215
1425
2.25
12.60
31.6
10.9
0.00
0.00
e9/l
0.08
184
1180
161
955
2.23
12.36
2.3
1.7
19.43
20.33
nmol/l
0.33
156
794
36
96
4.05
12.33
1.4
1.3
13.33
2.45
u/ml
—
9
13
40
116
3.75
12.20
3.8
2.9
—
—
—
0
0
23
25
9.74
11.67
1.6
1.2
61.43
50.85
u/l
0.35
23
20
219
1490
2.18
11.67
4.7
2.7
—
—
estimate
—
0
0
51
180
3.13
11.46
3.5
3.6
4.23
4.57
pmol/l
1.33
45
160
35
97
3.89
11.37
1.5
1.3
5.63
2.66
u/ml
—
9
18
126
702
2.22
11.04
2.9
1.6
1.38
1.20
mg/l
0.38
102
544
163
1008
2.12
10.91
2.6
2.1
137.61
249.60
u/l
1.03
158
957
29
73
4.23
10.71
1.6
1.5
—
—
—
0
0
17
14
12.67
9.95
4.0
3.6
2694.65
832.79
u/ml
0.49
17
14
66
295
2.51
9.45
4.8
2.6
37.91
33.44
u/l
0.51
57
249
30
85
3.76
9.44
6.2
3.4
2.46
2.13
index
0.15
22
55
28
76
3.91
9.35
1.2
1.2
66.83
39.23
u/ml
—
6
13
144
891
2.02
9.27
8.8
3.6
0.00
0.00
estimate
0.50
56
320
22
50
4.62
9.21
1.3
1.3
—
—
—
0
0
22
50
4.62
9.21
1.3
1.3
—
—
—
0
0
19
39
5.09
8.94
1.8
2.1
33.53
32.72
pg
0.44
19
39
32
101
3.38
8.58
1.8
1.6
0.02
0.21
iu/ml
—
6
15
75
371
2.29
8.53
6.3
3.1
7.95
7.19
umol/l
0.21
69
334
24
63
4.01
8.38
1.2
1.1
15.14
44.08
u/l
0.84
24
57
19
27
7.36
8.36
2.1
1.9
—
—
—
0
0
27
78
3.66
8.26
1.4
1.4
—
—
—
0
0
27
78
3.66
8.26
1.3
1.2
—
—
—
0
0
19
42
4.72
8.22
1.6
1.1
4.58
1.27
u/ml
0.54
12
15
181
1258
1.88
7.91
6.0
3.8
87.24
36.00
ng/l
0.63
152
935
18
41
4.57
7.51
1.7
1.2
3.75
8.25
u/ml
0.33
12
16
18
29
6.47
7.33
3.3
1.6
—
—
—
0
0
28
90
3.29
7.30
1.5
1.2
—
—
—
0
0
17
39
4.52
7.03
1.5
1.4
—
—
—
0
0
31
110
2.99
6.87
2.4
1.8
—
—
—
0
0
63
316
2.20
6.86
2.5
2.2
0.23
0.21
g/l
0.68
56
290
104
628
1.92
6.84
6.7
3.7
396.82
359.20
ng/l
0.06
97
494
16
26
6.39
6.54
2.6
1.8
—
—
—
0
0
16
26
6.39
6.54
2.6
1.8
—
—
—
0
0
16
26
6.39
6.54
2.6
1.8
—
—
—
0
0
18
35
5.36
6.41
2.1
1.7
90.28
89.07
%
0.28
18
35
135
904
1.79
6.30
8.4
3.0
0.34
0.10
estimate
0.30
58
276
101
624
1.86
6.11
1.7
1.8
442.32
434.09
pmol/l
0.13
92
513
11
11
10.27
6.07
2.8
1.2
151.73
55.41
ng/l
1.52
11
11
10
9
11.38
5.83
1.1
1.0
1592.90
1468.56
miu/ml
—
10
9
169
1233
1.69
5.66
9.0
3.4
0.00
0.02
estimate
0.96
57
293
28
105
2.81
5.64
1.9
1.7
—
—
—
0
0
12
17
7.26
5.48
2.2
3.0
—
—
—
0
0
11
14
8.06
5.38
1.1
2.0
—
—
—
0
0
11
14
8.06
5.38
1.1
2.0
—
—
—
0
0
16
44
3.76
5.26
1.0
1.1
—
—
—
0
0
5
0
+∞
5.22
5.2
0.0
—
—
—
0
0
338
3052
2.56
5.18
57.9
14.5
17.46
23.42
mg/l
5.62
321
2475
8
6
13.59
5.10
1.6
1.5
—
—
—
0
0
10
12
8.53
5.09
2.0
1.3
153.30
164.64
mmol/24h
—
10
12
12
20
6.17
4.95
7.9
2.8
0.50
1.05
index
2.10
12
20
24
90
2.78
4.85
1.4
1.3
298.83
304.66
ug/g
0.05
18
55
9
10
9.19
4.81
1.8
2.1
—
—
—
0
0
9
10
9.19
4.81
1.8
2.1
—
—
—
0
0
25
97
2.69
4.75
1.5
1.2
—
—
—
0
0
98
645
1.71
4.65
5.1
3.1
2.49
2.45
mmol/l
1.86
89
581
7
5
14.23
4.59
10.7
4.0
177.00
162.40
%
—
7
5
9
11
8.36
4.58
1.8
2.0
—
—
—
0
0
15
36
4.30
4.57
18.9
7.4
6.93
7.06
mmol/l
0.06
15
27
10
15
6.82
4.49
1.7
1.9
—
—
—
0
0
10
15
6.82
4.49
1.7
1.9
—
—
—
0
0
10
15
6.82
4.49
1.7
1.9
—
—
—
0
0
10
15
6.82
4.49
1.7
1.9
—
—
—
0
0
11
19
5.93
4.47
1.0
1.3
—
—
—
0
0
15
37
4.18
4.46
1.1
1.1
87.40
2.60
iu/ml
—
5
5
21
78
2.80
4.33
1.9
1.3
13713.12
24052.39
e6/l
0.53
16
56
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
8
9
9.06
4.30
10.9
2.9
142.00
128.44
%
—
8
9
24
97
2.58
4.22
1.3
1.3
—
—
—
0
0
9
13
7.07
4.18
2.2
1.3
—
—
—
0
0
24
98
2.55
4.14
1.5
1.2
—
—
—
0
0
7
7
10.16
4.02
2.9
1.0
76.43
100.29
%
—
7
7
324
2934
1.97
3.98
11.6
6.4
41.15
39.28
mmol/mol
2.36
316
2750
12
27
4.56
3.97
1.2
1.4
—
—
—
0
0
219
1807
1.53
3.80
3.8
2.9
—
—
—
0
0
9
16
5.74
3.68
1.0
1.3
—
—
—
0
0
273
2375
1.60
3.67
5.9
4.2
14.97
14.86
pmol/l
0.27
267
2143
23
98
2.44
3.65
2.0
1.6
—
—
—
0
0
11
25
4.50
3.65
1.4
1.2
—
—
—
0
0
11
25
4.50
3.65
1.4
1.3
—
—
—
0
0
11
25
4.50
3.65
1.4
1.3
—
—
—
0
0
11
25
4.50
3.65
1.4
1.3
—
—
—
0
0
13
35
3.81
3.63
1.5
1.3
106453.33
32840.50
e6/l
—
6
20
9
17
5.40
3.53
1.0
1.4
—
—
—
0
0
8
13
6.26
3.52
2.6
2.0
86.63
55.69
ug/l
—
8
13
339
3145
2.18
3.49
67.6
17.1
139.46
139.75
mmol/l
1.31
333
3081
339
3146
2.17
3.47
70.7
17.2
4.07
3.97
mmol/l
6.50
333
3074
12
32
3.84
3.42
1.3
1.3
—
—
—
0
0
8
14
5.82
3.36
1.1
1.1
—
—
—
0
0
11
28
4.02
3.31
1.4
1.3
—
—
—
0
0
9
19
4.83
3.26
1.6
1.2
—
—
—
0
0
10
24
4.25
3.22
1.2
1.4
—
—
—
0
0
13
40
3.33
3.17
1.5
1.3
1099.86
1831.59
e6/l
—
7
29
244
2101
1.49
3.16
5.6
3.3
60.00
48.28
u/l
1.18
232
1962
5
5
10.11
2.98
1.0
1.0
—
—
—
0
0
8
17
4.79
2.93
1.0
1.4
—
—
—
0
0
8
17
4.79
2.93
1.0
1.4
—
—
—
0
0
11
33
3.40
2.83
1.3
1.2
—
—
—
0
0
5
6
8.43
2.75
1.0
1.0
—
—
—
0
0
6
10
6.08
2.71
1.0
4.1
236.83
193.70
u/l
—
6
10
7
15
4.74
2.61
1.9
2.6
111.86
102.13
%
—
7
15
7
15
4.74
2.61
1.4
1.1
—
—
—
0
0
5
7
7.22
2.55
3.6
1.4
—
—
—
0
0
9
26
3.52
2.50
1.0
1.2
—
—
—
0
0
6
12
5.06
2.41
6.2
2.9
39.05
40.79
g/l
—
6
12
9
27
3.39
2.41
1.0
1.2
—
—
—
0
0
8
22
3.69
2.37
5.9
3.4
0.63
1.23
%
—
8
22
9
28
3.27
2.32
1.2
1.1
—
—
—
0
0
94
715
1.42
2.20
7.5
3.5
1.02
1.02
kg/l
2.01
73
474
16
74
2.22
2.18
1.0
1.2
—
—
—
0
0
16
74
2.22
2.18
1.2
1.1
—
2.87
—
0
11
320
2995
1.58
2.11
50.2
14.4
51.77
82.03
ml/min/173m2
52.58
312
2754
6
15
4.05
2.04
1.3
1.1
—
—
—
0
0
8
26
3.12
2.02
1.0
1.0
—
—
—
0
0
31
189
1.70
1.95
1.1
1.3
124.81
152.82
u/ml
—
9
78
6
17
3.57
1.84
1.3
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
18
3.37
1.75
1.5
1.2
—
—
—
0
0
5
13
3.88
1.72
2.2
2.3
—
—
—
0
0
340
3255
1.70
1.70
69.9
19.4
159.53
75.49
umol/l
27.82
335
3218
339
3245
1.68
1.67
32.9
11.9
23.81
26.62
u/l
3.60
334
3144
6
19
3.19
1.67
1.3
1.0
—
—
—
0
0
310
2915
1.43
1.64
6.5
4.4
1.56
1.27
mmol/l
8.24
300
2659
305
2860
1.42
1.64
7.0
5.3
2.21
1.93
mu/l
3.15
294
2613
39
266
1.52
1.59
2.5
2.5
18.20
6.61
ug/l
0.47
34
231
26
161
1.66
1.57
1.5
1.3
—
—
—
0
0
10
44
2.31
1.57
1.1
1.0
—
—
—
0
0
9
37
2.47
1.49
1.1
1.2
—
—
—
0
0
156
1350
1.27
1.46
2.5
2.0
1.45
1.32
mmol/l
1.18
137
1114
5
16
3.15
1.44
1.0
1.4
—
—
—
0
0
5
16
3.15
1.44
1.0
1.4
—
—
—
0
0
6
22
2.76
1.44
1.8
1.0
—
—
—
0
0
322
3065
1.45
1.43
7.6
5.2
4.39
4.60
mmol/l
3.16
314
2847
320
3048
1.42
1.36
7.6
5.1
1.37
1.46
mmol/l
4.12
311
2805
10
47
2.16
1.35
1.2
1.4
—
—
—
0
0
10
47
2.16
1.35
1.2
1.4
—
—
—
0
0
10
47
2.16
1.35
1.1
1.1
—
1.42
—
0
10
0
39
0.00
1.34
0.0
1.4
—
7.52
—
0
34
8
34
2.38
1.30
2.0
1.6
12.00
10.29
mmol/l
—
8
34
10
48
2.11
1.29
1.1
1.4
—
—
—
0
0
10
48
2.11
1.29
1.2
1.4
—
—
—
0
0
8
35
2.31
1.27
1.3
1.1
—
—
—
0
0
10
49
2.07
1.23
1.2
1.4
—
—
—
0
0
10
49
2.07
1.23
1.2
1.4
—
—
—
0
0
14
80
1.78
1.14
1.0
1.3
—
291.50
—
0
34
14
81
1.76
1.10
1.3
1.4
—
—
—
0
0
5
21
2.40
1.09
1.4
1.4
—
—
—
0
0
89
745
1.26
1.07
1.4
1.3
0.75
1.53
u/ml
0.90
22
218
20
298
0.65
1.06
2.3
2.2
—
—
—
0
0
7
33
2.14
1.06
1.3
1.1
—
—
—
0
0
18
272
0.64
1.02
1.9
2.1
—
—
—
0
0
7
35
2.02
1.00
1.0
1.4
—
—
—
0
0
7
126
0.55
0.90
1.9
2.0
—
—
—
0
0
12
72
1.69
0.86
1.5
2.3
3.47
7.04
iu/l
—
5
32
8
45
1.79
0.85
1.3
1.2
1.47
1.50
g/l
—
8
39
29
215
1.38
0.83
2.7
2.6
38.60
16.41
au/ml
—
5
16
341
3327
1.41
0.81
78.1
22.8
232.93
244.51
e9/l
2.41
335
3263
9
150
0.59
0.80
1.9
2.1
—
—
—
0
0
341
3328
1.41
0.79
77.7
22.7
92.61
91.21
fl
5.09
335
3294
341
3329
1.40
0.78
79.9
23.2
38.23
40.68
%
12.18
334
3291
341
3329
1.40
0.78
77.9
22.8
4.21
4.52
e12/l
15.83
334
3254
321
3109
1.28
0.77
8.1
6.0
2.46
2.69
mmol/l
5.14
310
2874
341
3330
1.40
0.77
78.6
22.9
125.84
136.46
g/l
21.20
335
3293
7
41
1.72
0.70
5.7
2.6
103.71
105.27
mmol/l
—
7
41
7
41
1.72
0.70
5.7
2.6
1.19
1.20
mmol/l
—
7
41
7
43
1.64
0.67
1.1
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.2
—
11.86
—
0
22
31
248
1.27
0.57
1.8
1.5
—
—
—
0
0
6
97
0.61
0.53
1.7
1.9
—
—
—
0
0
11
157
0.69
0.52
1.0
1.0
—
—
—
0
0
308
3004
1.17
0.46
8.4
5.2
6.05
5.96
mmol/l
0.57
288
2752
5
31
1.62
0.43
1.6
1.6
—
—
—
0
0
5
33
1.52
0.41
1.2
1.5
68.35
46.34
ug/l
—
5
33
0
17
0.00
0.40
0.0
1.3
—
—
—
0
0
60
534
1.15
0.40
1.5
1.5
—
—
—
0
0
132
1240
1.10
0.36
5.0
5.7
2.17
2.52
ug/l
0.37
123
1103
13
99
1.32
0.36
1.9
1.5
302.08
267.33
mu/l
0.18
13
94
6
46
1.31
0.33
1.5
4.1
—
—
—
0
0
65
591
1.12
0.33
1.3
1.4
88.62
30.20
iu/ml
0.77
20
186
15
119
1.27
0.32
1.4
1.3
20.58
26.10
iu/l
0.33
15
102
5
73
0.68
0.26
2.6
1.6
—
—
—
0
0
40
362
1.12
0.23
1.4
1.8
1.58
1.52
%
0.14
32
316
18
153
1.19
0.23
1.4
1.5
0.26
0.28
mg/l
—
9
75
8
101
0.79
0.21
1.0
1.1
1.38
1.53
g/l
—
8
101
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
37
403
0.91
0.18
2.2
1.6
—
—
—
0
0
17
148
1.16
0.17
2.5
3.8
1743.59
2129.01
u/ml
0.07
17
132
34
368
0.92
0.15
19.5
6.6
—
—
—
0
0
102
990
1.04
0.11
4.4
4.7
27.51
21.70
%
2.63
55
457
73
754
0.96
0.09
2.9
3.2
0.97
0.71
ug/l
1.10
49
485
9
103
0.87
0.06
1.3
1.2
0.87
0.92
g/l
—
9
103
34
354
0.96
0.05
2.3
4.7
3.19
37.08
ug/l
0.90
28
298
56
553
1.01
0.01
1.3
1.3
6.29
8.33
u/ml
0.19
16
225
12
122
0.98
0.00
1.2
1.8
40.83
39.10
nmol/l
0.15
12
115
0
5
0.00
0.00
0.0
2.2
—
1.17
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
86
0.93
-0.00
1.1
1.1
—
10.79
—
0
10
0
6
0.00
-0.00
0.0
5.3
—
11.13
—
0
6
5
49
1.02
-0.00
1.0
1.5
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint N14_RENALTUBULOINOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_RENALTUBULOINOTH | 2.925 [2.31, 3.71] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.263 |
During the follow-up period (1.1.1998 — 31.12.2019), 286 out of 748 females with N14_RENALTUBULOINOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_RENALTUBULOINOTH | 2.812 [2.18, 3.63] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 319 out of 809 males with N14_RENALTUBULOINOTH died.
Mortality risk
Mortality risk for people of age
years, who have N14_RENALTUBULOINOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.25% | 0.476% |
| 5 | 1.735% | 2.944% |
| 10 | 4.3% | 7.322% |
| 15 | 8.306% | 13.33% |
| 20 | 14.035% | 21.922% |
Relationships between endpoints
↥Index endpoint: N14_RENALTUBULOINOTH – Renal tubulo-interstitial disorders in diseases classified elsewhere
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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