eyelid disease: A disease involving the eyelid.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
601 |
4. Check minimum number of eventsNone |
601 |
5. Include endpointsNone |
601 |
6. Filter based on genotype QC (FinnGen only) |
536 |
Control definitions (FinnGen only)
- Control exclude
- H7_LIDLACRIMALORBIT
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other specified and unspecified disorders of eyelid
based on the number of shared cases.
Similar with more cases:
- Other disorders of eyelid
- Disorders of eyelid, lacrimal system and orbit
- Diseases of the eye and adnexa
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3094 | 1699 | 1382 |
| Only index persons | 2849 | 1573 | 1276 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.04 |
| Only index persons | 0.05 | 0.06 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 56.11 | 57.78 | 54.14 |
| Only index persons | 56.64 | 58.19 | 54.72 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 536 | 311 | 225 |
| Unadjusted period prevalence (%) | 0.11 | 0.11 | 0.10 |
| Median age at first event (years) | 63.13 | 61.79 | 64.99 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 553
- Matched controls
- 5530
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H02.8
ICD-10 Finland
Other specified disorders of eyelid
+∞
307.7
349
*
H02.3
ICD-10 Finland
Blepharochalasis
121.4
241.3
123
13
H02.9
ICD-10 Finland
Disorder of eyelid, unspecified
1008.7
215.1
197
*
CBB30
NOMESCO Finland
Excision of lesion of eyelid
14.2
71.3
68
54
H02.4
ICD-10 Finland
Ptosis of eyelid
109.9
70.9
76
8
H04.10
ICD-10 Finland
Dry eye syndrome
6.3
53.4
100
186
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
+∞
53.0
50
*
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
+∞
53.0
50
*
H00.1
ICD-10 Finland
Chalazion
11.1
42.8
47
46
CBJ50
NOMESCO Finland
Operation for ptosis of eyebrow
438.9
41.7
41
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.1
37.3
320
1698
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
369.5
35.4
35
*
CBG00
NOMESCO Finland
Epilation of cilia by electrolysis
319.0
30.1
30
*
CBA10
NOMESCO Finland
Biopsy of eyelid
27.1
27.9
38
15
H01.0
ICD-10 Finland
Blepharitis
5.0
26.1
59
128
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
6.2
25.8
46
80
F29
ICPC
Eye symptom/complaint other
3.5
25.3
98
318
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
+∞
23.1
22
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.8
23.1
146
628
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
19.9
19
*
CBJ30
NOMESCO Finland
Plastic repair of levator aponeurosis of eyelid
+∞
17.8
17
*
H02.5
ICD-10 Finland
Other disorders affecting eyelid function
+∞
16.7
16
*
CBB00
NOMESCO Finland
Excision of chalazion
92.9
16.7
18
*
CBN99
NOMESCO Finland
Other operation on eyelid for malposition
+∞
15.7
15
*
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
87.6
15.6
17
*
L17
ICPC
Foot/toe symptom/complaint
2.1
15.6
208
1218
H02.1
ICD-10 Finland
Ectropion of eyelid
164.5
15.6
16
*
WX110
NOMESCO Finland
Infiltration anesthesia
2.3
15.5
418
3184
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.1
14.9
212
1269
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
21.8
14.8
21
10
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
+∞
14.6
14
*
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
3.6
14.0
48
142
CBB21
NOMESCO Finland
Correction of lax skin and resection of herniated fat in upper eyelid
+∞
13.6
13
*
ZXA05
NOMESCO Finland
Left side
2.1
13.4
163
913
WX002
NOMESCO Finland
Sedation and analgesia
2.3
13.3
126
639
CB9S4
NOMESCO Finland
Photography of eyelids and eyebrows
51.3
12.9
15
*
CBN30
NOMESCO Finland
Shortening of canthal ligament
+∞
12.5
12
*
QAJ10
NOMESCO Finland
Browlift
+∞
12.5
12
*
M79.6
ICD-10 Finland
Pain in limb
1.9
12.5
270
1839
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
12.5
150
833
H00.00
ICD-10 Finland
Hordeolum
4.0
12.4
36
95
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
12.3
185
1114
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
4.8
12.3
28
61
ZXA10
NOMESCO Finland
Bilateral
2.2
12.0
118
606
CBN20
NOMESCO Finland
Shortening of eyelid retractors
+∞
11.5
11
*
E0000UV, ,
ATC
1.9
11.3
244
1646
M25.5
ICD-10 Finland
Pain in joint
1.9
11.0
200
1275
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.6
10.9
70
297
CD2S4
NOMESCO Finland
Photography of eye
15.9
10.9
17
11
XCK00
NOMESCO Finland
Perimetry
3.2
10.5
43
143
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
16.4
10.4
16
10
SAA01
NOMESCO Finland
Simple examination of mouth
1.9
10.3
401
3207
R23.8
ICD-10 Finland
Other and unspecified skin changes
2.0
10.3
135
768
S18
ICPC
Laceration/cut
1.8
10.1
286
2073
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.0
10.0
127
714
H02AB06
ATC
prednisolone; systemic
1.8
9.9
276
1988
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.9
9.7
166
1031
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
10.3
9.6
18
18
R60.0
ICD-10 Finland
Localized oedema
2.2
9.6
91
458
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.4
9.5
67
296
CFA20
NOMESCO Finland
Biopsy of conjunctiva
30.6
9.4
12
*
CBD99
NOMESCO Finland
Other plastic reconstruction of eyelid
+∞
9.4
9
*
3748X
ICD-9 Finland
Other disorders of eyelids, Other disorders of eyelid
+∞
9.4
9
*
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
22.1
9.4
13
6
F16
ICPC
Eyelid symptom/complaint
3.3
9.4
36
115
SFA00
NOMESCO Finland
Small restoration
2.2
9.3
88
442
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
2.8
9.2
46
171
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.6
9.0
56
233
R51.80
ICD-10 Finland
Headache
2.1
8.7
94
496
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
50.8
8.7
10
*
G51.0
ICD-10 Finland
Bell palsy
4.9
8.6
19
40
A02BC02
ATC
pantoprazole; systemic
1.8
8.6
388
3150
A02BC05
ATC
esomeprazole; systemic
1.7
8.6
232
1638
J05AB11
ATC
valaciclovir; oral
2.1
8.5
95
508
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.1
8.5
85
436
WX402
NOMESCO Finland
General anaesthesia
1.9
8.4
134
808
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.8
8.4
189
1264
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
8.4
211
1456
CBF10
NOMESCO Finland
Shortening of canthal ligaments and tarsal plate for ectropion
+∞
8.4
8
*
H05.9
ICD-10 Finland
Disorder of orbit, unspecified
+∞
8.4
8
*
CBB12
NOMESCO Finland
Resection of lax skin in lower eyelid
+∞
8.4
8
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.1
8.3
91
482
M54.5
ICD-10 Finland
Low back pain
1.7
8.3
209
1442
Z3229
NOMESCO Finland
Other healthcare associate professional
2.5
8.3
52
218
N02BE01
ATC
paracetamol; systemic, rectal
2.4
8.2
504
4484
H10
ICD-10 Finland
Conjunctivitis
2.7
8.1
46
183
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
8.1
283
2130
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
22.4
8.0
11
5
A06AC01
ATC
ispaghula (psylla seeds); oral
1.8
8.0
161
1042
ZXA00
NOMESCO Finland
Right side
1.8
7.9
152
969
N02AX02
ATC
tramadol; systemic, rectal
1.7
7.9
248
1811
M03BX02
ATC
tizanidine; oral
1.7
7.9
339
2685
UJF32
NOMESCO Finland
Coloscopy
1.8
7.8
154
989
J31.0
ICD-10 Finland
Chronic rhinitis
2.4
7.7
54
238
CBB99
NOMESCO Finland
Other excision or destruction of lesion of eyelid
18.7
7.6
11
6
Z71.8
ICD-10 Finland
Other specified counselling
1.7
7.5
191
1315
H062, E050,
ICD-10 Finland
+∞
7.3
7
*
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
+∞
7.3
7
*
H02.2
ICD-10 Finland
Lagophthalmos
+∞
7.3
7
*
CBG10
NOMESCO Finland
Cryotherapy for trichiasis
+∞
7.3
7
*
SAA02
NOMESCO Finland
Basic examination of mouth
1.7
7.3
355
2876
CBB50
NOMESCO Finland
Excision of lesion of eyelid and reconstruction using graft or flap
16.0
7.3
11
7
Z01.2
ICD-10 Finland
Dental examination
1.6
7.2
249
1848
WZC00
NOMESCO Finland
Treatment plan or consultation
1.7
7.1
204
1446
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.4
7.0
47
203
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.3
7.0
56
262
WX720
NOMESCO Finland
Own respiration
2.7
6.9
37
143
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
14.0
6.9
11
8
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.2
6.9
60
291
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.6
6.9
295
2302
C44.11
ICD-10 Finland
Basocellular carcinoma of the skin of the eyelids including the corner of the eye
6.8
6.9
16
24
L82
ICD-10 Finland
Seborrhoeic keratosis
1.8
6.8
118
727
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
6.8
129
817
S01XA18
ATC
ciclosporin; ophthalmic
40.6
6.8
8
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
6.7
68
350
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
3.7
6.7
21
59
I10
ICD-10 Finland
Essential (primary) hypertension
1.6
6.6
350
2859
N03AX16
ATC
[U] pregabalin
1.7
6.6
132
848
ZXE00
NOMESCO Finland
One hour or less
1.6
6.5
206
1487
S01GX01
ATC
cromoglicic acid; ophthalmic
1.8
6.5
107
648
H03BB01
ATC
carbimazole; oral
3.0
6.5
28
96
M54.4
ICD-10 Finland
Lumbago with sciatica
1.8
6.5
108
656
A11
ICPC
Chest pain NOS
2.2
6.5
54
257
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.0
6.5
78
427
D31.6
ICD-10 Finland
Benign neoplasm: Orbit, unspecified
70.6
6.4
7
*
H57.1
ICD-10 Finland
Ocular pain
3.1
6.3
25
82
TCB10
NOMESCO Finland
Simple epilation of cilia
+∞
6.3
6
*
CBK99
NOMESCO Finland
Other operation for retraction of eyelid
+∞
6.3
6
*
CBG99
NOMESCO Finland
Other operation for trichiasis
+∞
6.3
6
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
6.2
107
656
H25.1
ICD-10 Finland
Senile nuclear cataract
1.7
6.2
157
1070
H10.5
ICD-10 Finland
Blepharoconjunctivitis
5.4
6.2
17
32
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.7
6.2
150
1012
L01
ICPC
Neck symptom/complaint
1.8
6.2
92
540
N05CF01
ATC
zopiclone; oral
1.6
6.2
182
1289
M48.0
ICD-10 Finland
Spinal stenosis
1.9
6.2
79
442
F72
ICPC
Blepharitis/stye/chalazion
3.5
6.1
20
58
G44.2
ICD-10 Finland
Tension-type headache
1.9
6.1
78
437
R01AD09
ATC
mometasone; nasal
1.6
6.0
238
1803
R52.9
ICD-10 Finland
Pain, unspecified
2.1
6.0
61
314
C10AA07
ATC
rosuvastatin; oral
1.6
6.0
198
1439
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
43
122
3.74
13.36
3.5
1.7
5.69
58.91
iu/l
0.48
19
43
377
2850
2.01
12.96
10.6
9.9
4.11
4.12
e9/l
0.03
333
2490
310
2231
1.89
11.90
5.8
5.2
36.30
35.45
g/l
2.06
294
2107
344
2576
1.89
11.49
7.2
7.7
1.21
1.21
mmol/l
0.70
315
2234
317
2314
1.87
11.47
7.1
6.9
1.20
1.21
mmol/l
1.05
304
2139
530
4728
3.91
10.71
20.1
16.3
21.98
24.70
mg/l
1.31
464
3887
439
3614
2.04
10.46
4.9
4.4
11.72
12.41
mm/h
0.51
419
3370
156
950
1.89
9.68
4.3
4.1
93.55
456.58
ng/l
2.75
124
759
453
3818
2.03
9.42
9.3
8.4
76.10
80.23
u/l
1.94
440
3606
113
626
2.01
9.21
6.4
9.8
0.85
0.96
mmol/l
0.10
97
516
129
749
1.94
9.19
6.2
8.0
104.06
104.26
mmol/l
0.15
129
749
299
2260
1.70
8.57
3.4
3.0
108.98
136.92
ug/l
1.73
281
2102
337
2635
1.71
8.48
5.3
3.9
0.05
0.01
estimate
0.33
56
509
331
2588
1.69
8.22
5.1
3.9
0.00
0.00
estimate
-0.00
60
529
144
896
1.82
8.18
3.2
3.0
0.99
1.07
e6/l
0.08
79
466
332
2614
1.68
7.88
5.2
3.9
0.00
3.41
estimate
0.50
61
551
204
1429
1.68
7.52
3.6
3.2
0.16
0.43
e6/l
3.70
149
1039
188
1289
1.69
7.51
2.9
2.8
333.15
345.51
umol/l
1.04
169
1141
366
2977
1.68
7.47
5.6
5.4
6.46
6.73
mmol/l
2.45
350
2833
437
3736
1.81
7.40
5.3
4.2
14.79
14.88
pmol/l
0.33
412
3412
495
4440
2.10
6.77
6.6
5.3
1.86
1.93
mu/l
0.65
470
4072
335
2709
1.60
6.59
6.7
6.8
10.72
11.42
umol/l
0.86
323
2589
284
2210
1.59
6.58
2.8
2.5
75.65
78.09
nmol/l
0.79
269
1978
165
1127
1.66
6.54
1.7
1.6
1.21
1.35
mg/l
0.26
140
886
509
4631
2.25
6.42
6.4
5.3
5.92
5.99
mmol/l
0.78
482
4238
151
1015
1.67
6.34
2.9
3.2
2.44
2.45
mmol/l
0.52
137
908
181
1279
1.62
6.22
2.5
2.2
2.55
2.97
mg/l
1.46
160
1107
286
2248
1.56
6.21
2.4
2.1
97.61
95.72
pmol/l
0.32
153
1181
224
1669
1.58
6.13
3.9
3.4
20.98
58.07
e6/l
2.22
169
1275
233
1753
1.57
6.11
3.3
3.8
2.35
2.35
mmol/l
0.30
217
1574
73
403
1.93
5.92
2.9
2.6
61.76
65.83
ml/min/173m2
0.38
37
173
14
22
6.50
5.89
1.4
4.8
620.64
912.64
u/ml
0.46
14
22
207
1532
1.56
5.75
1.7
1.7
20.47
20.33
nmol/l
0.04
188
1277
537
5045
3.23
5.61
27.9
21.6
78.23
78.00
umol/l
0.07
537
4990
290
2334
1.51
5.35
2.9
2.8
—
—
estimate
—
0
0
525
4892
2.45
5.33
25.5
19.8
3.97
3.98
mmol/l
0.16
520
4791
542
5134
3.80
5.27
32.5
25.0
247.55
248.66
e9/l
0.16
537
5030
542
5135
3.79
5.25
32.4
25.0
4.47
4.48
e12/l
0.17
532
5019
498
4560
1.93
5.15
7.6
6.7
39.39
39.66
mmol/mol
0.31
478
4267
517
4797
2.19
5.13
7.3
6.0
2.66
2.69
mmol/l
0.33
494
4434
122
819
1.63
5.03
3.7
3.1
1.98
2.29
e6/l
0.17
59
392
493
4506
1.87
5.03
4.9
4.5
1.35
1.30
mmol/l
0.72
464
4116
510
4719
2.04
4.93
6.2
5.3
4.60
4.63
mmol/l
0.28
490
4380
523
4885
2.30
4.93
25.2
19.7
139.55
139.70
mmol/l
0.69
518
4791
229
1780
1.49
4.86
3.6
3.4
6.92
7.44
mmol/l
1.31
203
1504
223
1726
1.49
4.83
3.7
3.3
28.13
33.71
u/l
2.50
218
1634
159
1151
1.54
4.72
6.3
4.1
1.02
1.02
kg/l
0.22
115
772
87
544
1.71
4.69
3.1
3.4
1.97
1.95
mmol/l
0.01
72
461
331
2781
1.47
4.66
3.1
2.8
—
—
—
0
0
292
2397
1.46
4.62
17.0
14.6
1.25
1.25
inr
0.02
239
1990
12
22
5.55
4.62
2.1
2.5
—
—
—
0
0
57
315
1.90
4.62
2.7
3.2
24.30
24.23
mmol/l
0.06
57
310
258
2080
1.45
4.42
2.1
1.9
1.40
1.35
mmol/l
0.37
224
1737
506
4700
1.90
4.37
5.8
5.2
1.45
1.48
mmol/l
0.66
483
4334
94
612
1.65
4.35
1.9
2.0
—
—
—
0
0
208
1614
1.46
4.34
2.5
2.1
218.73
248.91
u/l
0.18
196
1526
206
1598
1.46
4.30
3.1
3.2
750.22
1304.80
ng/l
5.22
181
1371
98
649
1.62
4.24
1.8
1.9
—
—
—
0
0
155
1142
1.50
4.17
2.8
2.7
6.29
5.86
e6/l
0.09
141
1050
76
474
1.70
4.14
2.7
2.5
31.95
33.59
u/l
0.20
66
399
15
47
3.25
4.08
1.3
1.2
—
—
—
0
0
55
316
1.82
3.97
3.7
2.4
0.63
0.62
%
0.08
55
316
113
787
1.55
3.93
2.6
2.5
2.35
2.31
g/l
0.31
107
727
14
43
3.31
3.93
3.3
2.9
779.64
787.77
mg
0.01
14
43
205
1624
1.42
3.70
3.0
2.6
61.05
110.53
u/l
0.50
194
1506
51
294
1.81
3.65
4.1
3.6
49.10
48.77
%
0.03
51
289
107
751
1.53
3.58
1.5
1.5
—
—
—
0
0
104
727
1.53
3.55
2.4
2.5
21.89
22.46
%
0.18
97
680
216
1739
1.40
3.51
4.4
4.3
10.61
7.99
mg/mmol
0.42
139
1083
67
424
1.66
3.46
3.0
2.4
5.39
7.83
ug/l
0.87
61
381
99
690
1.53
3.42
5.3
5.5
1.03
1.04
mmol/l
0.06
94
634
64
403
1.67
3.37
3.5
3.5
84.81
82.23
ng/l
0.07
54
352
117
851
1.48
3.29
2.6
2.5
13.59
12.88
umol/l
0.47
111
795
238
1966
1.37
3.24
5.3
3.9
0.00
0.02
estimate
1.66
49
445
110
795
1.48
3.19
1.7
1.9
29.01
29.49
s
0.54
104
775
49
292
1.74
3.16
2.6
2.4
17.94
24.04
au/ml
—
5
24
17
69
2.51
2.98
1.1
1.1
—
—
—
0
0
40
659
0.58
2.90
5.4
5.1
30.72
32.29
%
0.35
29
430
112
828
1.44
2.88
1.5
1.7
1036.74
1207.79
nmol/l
1.24
97
629
119
891
1.43
2.86
2.9
3.4
0.82
0.82
mmol/l
0.04
111
845
365
3262
1.35
2.80
3.7
3.3
46.25
51.48
u/l
0.81
344
3053
110
824
1.42
2.63
1.2
1.3
1.19
12.59
u/ml
5.03
38
328
36
212
1.75
2.46
1.4
2.2
4.53
7.27
iu/ml
—
6
61
490
4633
1.51
2.44
18.8
15.8
78.91
79.52
ml/min/173m2
0.28
467
4300
23
118
1.99
2.39
4.0
2.9
4.08
2.29
index
0.54
12
69
59
398
1.54
2.38
1.7
1.5
—
—
—
0
0
8
23
3.51
2.27
1.0
1.0
—
—
—
0
0
117
908
1.37
2.26
1.3
1.3
21.59
33.82
iu/ml
1.17
33
272
16
73
2.23
2.23
1.2
1.2
1.88
10.15
u/ml
—
8
33
140
1121
1.33
2.21
1.3
1.3
1.04
2.02
u/ml
0.98
29
308
6
15
4.03
2.04
1.0
2.0
—
—
—
0
0
9
32
2.84
2.01
1.4
1.3
—
—
—
0
0
77
575
1.39
1.89
3.3
2.8
4.81
7.73
umol/l
3.36
71
508
33
206
1.64
1.87
3.0
1.8
—
—
—
0
0
12
53
2.29
1.82
1.3
1.3
0.23
0.19
nmol/l
—
7
40
109
871
1.31
1.73
2.1
2.0
—
—
—
0
0
7
24
2.94
1.72
3.7
7.1
—
33.50
—
0
6
7
24
2.94
1.72
2.7
1.8
86.00
55.36
ug/l
—
7
24
150
1256
1.27
1.66
2.2
2.4
—
—
—
0
0
21
120
1.78
1.64
1.3
1.1
—
—
—
0
0
7
26
2.71
1.58
7.1
2.9
0.86
0.85
index
—
7
26
21
124
1.72
1.49
1.1
1.3
—
—
—
0
0
49
355
1.42
1.46
1.7
1.6
—
—
—
0
0
22
133
1.68
1.44
1.1
1.2
—
—
—
0
0
149
1268
1.24
1.42
5.4
4.5
22.40
21.78
%
0.15
75
610
126
1060
1.24
1.33
1.6
1.7
445.45
32688352.60
pmol/l
1.20
111
878
221
1971
1.20
1.31
4.7
3.8
227.77
67.02
ng/l
0.41
158
1464
8
35
2.30
1.27
1.3
1.0
—
—
—
0
0
21
131
1.63
1.25
1.2
1.2
—
—
—
0
0
8
36
2.24
1.24
1.5
1.1
—
—
—
0
0
15
85
1.79
1.24
1.7
1.4
—
—
—
0
0
15
85
1.79
1.24
1.7
1.4
—
—
—
0
0
25
165
1.54
1.19
2.0
1.9
36.56
40.89
nmol/l
0.51
25
157
24
157
1.55
1.19
1.1
1.2
—
—
—
0
0
43
317
1.39
1.19
1.7
1.7
—
—
—
0
0
21
134
1.59
1.16
1.1
1.2
—
—
—
0
0
5
20
2.51
1.15
2.6
2.3
—
—
—
0
0
5
20
2.51
1.15
2.6
2.3
—
—
—
0
0
16
95
1.70
1.15
2.1
3.0
9.14
8.76
pmol/l
0.06
16
95
7
30
2.35
1.12
1.3
1.8
—
—
—
0
0
26
176
1.50
1.12
1.4
2.1
3.97
3.93
mg/l
0.01
21
133
10
51
1.98
1.12
3.8
2.5
—
—
—
0
0
179
1589
1.19
1.09
6.0
5.6
1.76
2.71
ug/l
2.15
165
1416
5
21
2.39
1.09
2.6
2.3
—
—
—
0
0
8
41
1.96
1.09
1.3
1.1
—
—
—
0
0
25
171
1.48
1.04
3.0
1.7
—
—
—
0
0
5
22
2.28
1.03
1.0
1.1
—
—
—
0
0
70
568
1.27
1.03
2.0
1.7
1.48
1.47
%
0.03
62
499
14
83
1.70
1.02
1.6
1.2
192.00
160.21
au/ml
—
5
26
53
415
1.31
1.02
2.2
2.4
12.12
13.18
nmol/l
0.43
45
377
9
48
1.89
1.01
1.6
1.3
—
—
—
0
0
21
140
1.52
0.99
1.8
1.7
—
—
—
0
0
164
1458
1.18
0.98
6.7
4.0
0.00
0.00
estimate
0.50
51
501
9
51
1.78
0.95
4.0
3.9
—
—
—
0
0
82
685
1.23
0.94
1.5
1.5
—
—
—
0
0
6
27
2.24
0.93
2.3
2.1
—
—
—
0
0
6
27
2.24
0.93
2.3
2.1
—
—
—
0
0
6
27
2.24
0.93
1.0
1.2
—
—
—
0
0
6
27
2.24
0.93
2.3
2.1
—
—
—
0
0
6
27
2.24
0.93
2.3
2.1
—
—
—
0
0
51
403
1.29
0.93
2.4
1.9
—
—
—
0
0
14
86
1.64
0.91
1.4
1.4
—
—
—
0
0
17
110
1.56
0.91
1.5
1.2
3.51
3.62
mmol/l
0.26
17
105
11
63
1.76
0.90
1.2
1.4
0.17
0.28
nmol/l
1.30
11
46
10
56
1.80
0.88
2.2
2.0
—
—
—
0
0
8
43
1.87
0.87
2.6
1.4
—
—
—
0
0
6
30
2.01
0.87
2.8
1.9
53.17
124.22
ng/l
—
6
30
8
44
1.83
0.86
1.3
1.1
—
—
—
0
0
12
72
1.68
0.85
1.5
1.5
—
—
—
0
0
156
1401
1.16
0.81
3.5
3.4
0.06
0.01
estimate
0.40
48
435
10
58
1.74
0.80
1.8
1.8
—
—
—
0
0
10
58
1.74
0.80
1.8
1.8
—
—
—
0
0
10
58
1.74
0.80
1.8
1.8
—
—
—
0
0
15
98
1.55
0.79
3.5
4.2
22.90
25.10
mg/l
—
10
73
23
166
1.40
0.77
1.3
1.5
—
—
—
0
0
29
218
1.35
0.76
1.4
1.3
—
—
—
0
0
6
34
1.77
0.76
1.3
1.3
—
—
—
0
0
6
34
1.77
0.76
1.3
1.3
—
—
—
0
0
21
150
1.42
0.74
1.1
1.1
—
1.26
—
0
7
39
310
1.28
0.71
1.2
1.2
107.42
143.16
u/ml
0.20
15
114
20
143
1.41
0.71
1.1
1.2
—
1.88
—
0
13
17
118
1.45
0.70
2.1
1.5
—
—
—
0
0
10
61
1.65
0.69
2.2
2.0
—
—
—
0
0
20
144
1.40
0.69
1.1
1.2
—
10.21
—
0
22
7
42
1.68
0.68
1.3
1.1
121.29
100.83
pmol/l
—
7
42
21
153
1.39
0.68
1.3
1.6
0.00
0.10
iu/ml
—
6
27
45
368
1.24
0.66
2.4
1.9
—
—
—
0
0
24
180
1.35
0.66
2.7
2.9
—
—
—
0
0
28
217
1.31
0.63
1.6
1.9
1.28
1.51
g/l
0.65
22
200
17
121
1.42
0.63
1.6
1.6
—
—
—
0
0
10
64
1.57
0.59
2.3
1.9
10.14
10.63
mmol/l
—
10
64
20
149
1.36
0.58
1.4
1.4
272.18
292.10
ug/g
0.13
14
88
6
36
1.67
0.57
1.0
1.3
—
—
—
0
0
10
65
1.55
0.56
1.1
2.6
1.22
1.19
mmol/l
—
10
65
6
37
1.63
0.55
1.0
1.3
—
—
—
0
0
18
133
1.37
0.55
2.7
1.9
230.00
212.55
pmol/l
0.29
18
124
12
82
1.47
0.54
2.9
2.6
—
858.11
—
0
9
18
134
1.35
0.53
1.8
1.7
—
—
—
0
0
13
181
0.71
0.53
2.1
1.8
—
—
—
0
0
6
39
1.54
0.53
1.0
1.2
—
—
—
0
0
10
66
1.52
0.53
1.1
2.6
107.40
105.52
mmol/l
—
10
66
19
144
1.33
0.51
1.2
1.2
—
—
—
0
0
25
312
0.79
0.50
3.0
3.4
2.01
2.02
mmol/l
0.00
17
246
18
136
1.33
0.49
2.2
1.6
—
—
—
0
0
69
610
1.15
0.47
12.2
7.2
—
—
—
0
0
7
50
1.41
0.45
1.0
1.1
—
—
—
0
0
20
157
1.28
0.44
1.6
1.4
—
—
—
0
0
5
31
1.62
0.43
7.6
4.2
61.00
143.19
nmol/l
—
5
31
16
122
1.32
0.42
1.1
1.2
—
9.44
—
0
9
17
131
1.31
0.42
1.5
1.5
—
—
—
0
0
14
105
1.34
0.41
1.6
1.6
—
—
—
0
0
5
33
1.52
0.41
3.2
2.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.8
—
2.19
—
0
7
5
34
1.47
0.40
1.0
1.2
—
—
—
0
0
5
35
1.43
0.39
1.8
1.2
—
—
—
0
0
5
35
1.43
0.39
1.0
1.2
—
—
—
0
0
22
178
1.25
0.39
1.6
1.6
12.12
10.67
u/ml
—
5
31
102
938
1.11
0.39
3.0
3.1
0.63
0.79
ug/l
1.34
73
590
5
36
1.39
0.38
1.0
1.2
—
—
—
0
0
5
36
1.39
0.38
1.0
1.2
—
—
—
0
0
6
44
1.37
0.34
1.0
1.2
—
—
—
0
0
19
154
1.24
0.34
1.9
1.8
—
—
—
0
0
12
91
1.33
0.34
2.0
1.8
—
—
—
0
0
13
102
1.28
0.30
1.5
1.6
—
—
—
0
0
7
56
1.25
0.29
1.7
1.4
—
—
—
0
0
16
194
0.82
0.28
2.6
2.0
—
—
—
0
0
13
159
0.81
0.25
2.6
3.9
1.35
2.38
ratio
—
7
95
10
125
0.80
0.23
1.5
1.4
—
—
—
0
0
12
146
0.82
0.22
1.2
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
11
89
1.24
0.21
1.3
1.1
196.17
237.22
u/ml
—
6
49
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
6
48
1.25
0.20
1.5
1.1
—
—
—
0
0
6
52
1.16
0.19
2.3
1.6
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
17
147
1.16
0.18
3.9
2.7
0.33
0.34
iu/ml
0.06
11
80
39
358
1.10
0.18
1.9
1.9
3.52
3.50
mmol/l
0.03
28
283
7
63
1.11
0.17
7.0
3.1
2.43
6.16
nmol/l
—
7
63
8
69
1.16
0.16
1.6
1.6
—
—
—
0
0
59
556
1.07
0.15
4.5
4.5
264.49
29.76
ug/l
0.43
51
464
30
274
1.10
0.15
1.6
1.5
—
—
—
0
0
9
83
1.09
0.14
4.9
5.9
347.33
362.70
umol/l
—
9
77
16
141
1.14
0.14
1.3
1.3
—
—
—
0
0
12
138
0.87
0.13
1.9
1.6
—
—
—
0
0
5
44
1.14
0.10
1.0
1.0
—
—
—
0
0
25
232
1.08
0.10
1.0
1.0
—
—
—
0
0
5
47
1.06
0.09
1.0
1.3
—
—
—
0
0
16
145
1.11
0.09
1.8
1.5
1740.30
14310.14
e6/l
—
10
111
5
48
1.04
0.09
2.6
1.5
—
—
—
0
0
6
56
1.07
0.08
1.0
1.2
40.17
48.75
u/l
—
6
50
5
60
0.83
0.08
1.2
1.4
12.16
30.51
u/l
—
5
51
5
60
0.83
0.08
1.4
1.5
—
—
—
0
0
10
88
1.14
0.08
1.7
1.7
—
—
—
0
0
6
73
0.82
0.07
1.0
1.0
—
—
—
0
0
6
74
0.81
0.07
1.7
1.7
47.33
61.22
ug/l
—
6
63
15
163
0.92
0.07
1.1
1.2
1.62
1.56
g/l
0.39
15
163
8
90
0.89
0.07
1.6
1.4
—
145.71
—
0
7
21
223
0.94
0.06
2.2
1.6
0.13
0.32
mg/l
3.48
11
96
13
138
0.94
0.02
1.3
1.3
201.01
251.97
miu/ml
—
7
63
14
133
1.05
0.01
2.6
2.8
8.96
7.93
kpa
1.33
14
133
17
166
1.02
0.00
1.6
1.2
0.78
0.93
g/l
2.17
17
166
51
505
1.01
0.00
3.1
3.4
—
—
—
0
0
19
187
1.02
0.00
2.6
2.7
22.92
25.11
mmol/l
2.05
19
187
48
481
1.00
0.00
2.2
2.1
3.54
3.52
ratio
0.05
38
404
7
75
0.93
0.00
1.4
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
1.28
—
0
8
5
50
1.00
-0.00
1.6
1.1
1.76
1.80
nmol/l
—
5
43
0
5
0.00
-0.00
0.0
1.6
—
5.66
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
1.19
—
0
6
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.1
—
36.75
—
0
8
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
10.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_EYELIDNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_EYELIDNAS | 0.896 [0.7, 1.15] | 0.384 |
| Birth year | 0.992 [0.98, 1.0] | 0.073 |
During the follow-up period (1.1.1998 — 31.12.2019), 111 out of 1323 females with H7_EYELIDNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_EYELIDNAS | 0.876 [0.66, 1.16] | 0.352 |
| Birth year | 0.995 [0.99, 1.0] | 0.281 |
During the follow-up period (1.1.1998 — 31.12.2019), 111 out of 1125 males with H7_EYELIDNAS died.
Mortality risk
Mortality risk for people of age
years, who have H7_EYELIDNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.082% | 0.185% |
| 5 | 0.511% | 1.379% |
| 10 | 1.246% | 3.172% |
| 15 | 2.316% | 5.973% |
| 20 | 4.031% | 10.469% |
Relationships between endpoints
↥Index endpoint: H7_EYELIDNAS – Other specified and unspecified disorders of eyelid
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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