info icon

This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Need for immunization against other single infectious diseases

Z21_NEED_IMMUNI_OTH_SINGLE_INFECTIOUS_DISEA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Z26
  • Cause of death: ICD-10 Z26

2 out of 7 registries used, show all original rules.

56

4. Check minimum number of events

None

56

5. Include endpoints

None

56

6. Filter based on genotype QC (FinnGen only)

45

Control definitions (FinnGen only)

Control exclude
Z21_PERSONS_W_POTEN_HEALTH_HAZARDS_RELATED_COMMUNICAB_DISEA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Z2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 45 25 20
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 57.35 57.01 57.77

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
50
Matched controls
500
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Z26.8
ICD-10 Finland
Need for immunization against other specified single infectious diseases
655.9
32.9
29
*
Z26.9
ICD-10 Finland
Need for immunization against unspecified infectious disease
75.9
20.3
22
5
Z49.1
ICD-10 Finland
Extracorporeal dialysis
+∞
20.1
18
*
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
107.7
19.4
20
*
TK800
NOMESCO Finland
Hemodialysis
250.2
17.7
17
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
46.0
16.8
20
7
A11CC03
ATC
alfacalcidol; systemic
125.1
16.8
17
*
Z49.0
ICD-10 Finland
Preparatory care for dialysis
228.8
16.5
16
*
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
189.4
14.2
14
*
V03AE01
ATC
polystyrene sulfonate; oral
189.4
14.2
14
*
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
+∞
14.2
13
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
52.1
13.1
15
*
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
57.0
11.6
13
*
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
+∞
10.8
10
*
N18.8
ICD-10 Finland
Other chronic renal failure
51.3
10.5
12
*
XCH00
NOMESCO Finland
Eye pressure measurement
20.7
10.3
15
10
137
Kela drug reimbursment
Uraemia requiring dialysis
68.9
10.1
11
*
WW500
NOMESCO Finland
Blood transfusion
18.8
9.4
14
10
XCW99
NOMESCO Finland
Other investigative procedure of eye
12.2
9.3
17
20
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
17.1
9.0
14
11
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
61.1
9.0
10
*
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
61.1
9.0
10
*
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
61.1
9.0
10
*
Z13.1
ICD-10 Finland
Special screening examination for diabetes mellitus
61.1
9.0
10
*
Z49.2
ICD-10 Finland
Other dialysis
107.4
8.7
9
*
B05DB
ATC
Hypertonic solutions
+∞
8.6
8
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
+∞
8.6
8
*
WW200
NOMESCO Finland
Immunization
27.5
8.4
11
5
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.9
8.3
21
55
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
12.1
8.3
15
17
B05DA
ATC
Isotonic solutions
53.7
8.0
9
*
C03CA01
ATC
furosemide; systemic
5.6
8.0
22
62
WZC30
NOMESCO Finland
Teaching
5.6
7.9
21
57
SPAT1262
SPAT
Handing over of treatment supplies
6.3
7.9
17
38
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
5.2
7.7
24
75
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
93.4
7.6
8
*
ZX120
NOMESCO Finland
Intravenous
9.3
7.6
16
24
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
24.4
7.5
10
5
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
24.4
7.5
10
5
N02AX02
ATC
tramadol; systemic, rectal
5.0
7.4
30
115
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
20.3
7.1
10
6
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
46.5
7.0
8
*
V03AE02
ATC
sevelamer; oral
46.5
7.0
8
*
J01FF01
ATC
clindamycin; systemic
4.7
6.6
23
77
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
79.6
6.6
7
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.6
6.4
33
148
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
+∞
6.4
6
*
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
+∞
6.4
6
*
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
7.2
6.2
15
28
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
11.4
6.2
11
12

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
17
0
+∞
18.93
12.2
0.0
389.41
—
ng/l
—
17
0
27
55
9.50
14.66
20.6
8.5
—
—
—
0
0
23
41
9.54
13.92
42.0
5.5
62.40
69.04
e9/l
0.71
23
30
28
63
8.83
13.78
37.6
6.6
6.18
5.63
kpa
2.39
28
63
29
68
8.77
13.73
46.1
7.8
1.45
1.22
mmol/l
1.72
29
63
22
21
17.70
13.57
41.9
3.2
23.98
23.75
mmol/l
0.09
22
21
27
64
8.00
12.46
17.1
2.3
2.01
2.31
g/l
1.39
27
58
27
66
7.72
12.03
18.2
2.3
10.33
14.30
umol/l
3.04
27
60
17
15
16.45
10.58
3.2
1.2
—
—
—
0
0
13
7
24.37
9.53
2.6
5.7
0.94
1.19
mmol/l
—
13
7
23
62
6.02
8.87
4.7
3.5
30.50
29.73
s
0.26
23
62
18
41
6.30
8.22
69.9
4.8
7.38
7.31
ph
1.01
18
31
20
55
5.39
7.37
3.9
2.1
—
—
—
0
0
24
83
4.64
6.61
16.9
2.6
3.69
4.36
e6/l
0.15
24
74
6
0
+∞
6.37
6.0
0.0
297.33
—
umol/l
—
6
0
6
0
+∞
6.37
6.0
0.0
14.42
—
mmol/l
—
6
0
6
0
+∞
6.37
45.0
0.0
126.00
—
e6/l
—
6
0
17
47
4.97
6.11
4.5
1.6
—
—
—
0
0
42
250
5.24
5.64
10.7
7.9
0.26
0.19
e9/l
1.15
37
217
41
242
4.84
5.33
11.0
7.5
0.04
0.04
e9/l
0.13
35
203
26
111
3.80
5.11
12.0
3.8
403.15
327.46
umol/l
2.29
26
95
41
251
4.51
4.96
11.0
7.8
1.63
2.14
e9/l
2.67
36
220
31
152
3.74
4.89
14.0
4.4
14.93
26.65
e6/l
0.51
25
100
28
129
3.66
4.85
15.0
3.8
108.86
8.92
mg/mmol
2.64
21
77
27
124
3.56
4.66
3.4
3.3
—
—
—
0
0
40
240
4.33
4.51
11.2
7.6
0.63
0.57
e9/l
0.88
34
203
24
105
3.47
4.42
5.8
2.4
—
—
—
0
0
23
104
3.24
3.94
6.3
3.9
—
—
—
0
0
11
25
5.33
3.90
17.3
16.8
1.83
1.07
mg/l
1.69
11
25
41
270
3.87
3.87
11.3
12.5
4.29
4.11
e9/l
0.21
34
232
15
52
3.69
3.86
7.1
9.3
104.20
103.75
mmol/l
0.10
15
52
23
109
3.06
3.58
18.2
1.9
1.77
2.73
mg/l
2.90
23
90
14
49
3.58
3.53
8.9
8.7
—
—
—
0
0
6
7
9.52
3.36
1.0
1.1
75.02
35.69
mg/l
—
6
7
6
7
9.52
3.36
1.0
1.1
76.33
21.16
mg/l
—
6
7
27
145
2.87
3.29
2.8
2.0
92.33
93.96
pmol/l
—
6
76
13
46
3.47
3.20
10.3
7.0
23.85
23.74
mmol/l
0.06
13
46
23
115
2.85
3.18
4.7
2.1
—
—
—
0
0
6
8
8.32
3.14
1.2
1.1
—
—
—
0
0
34
211
2.91
3.09
16.5
7.8
15.41
12.46
umol/l
0.19
34
202
30
181
2.64
2.78
4.8
3.4
5.70
6.13
ph
1.66
22
95
14
57
3.02
2.74
10.9
7.0
4.76
5.35
kpa
0.71
14
57
25
139
2.60
2.73
5.8
2.6
—
—
—
0
0
36
440
0.35
2.49
26.8
12.7
—
—
—
0
0
7
17
4.60
2.46
1.1
1.1
—
—
—
0
0
9
28
3.69
2.45
6.3
6.4
126.33
127.43
g/l
—
9
28
27
166
2.36
2.27
12.1
8.0
—
—
—
0
0
39
286
2.65
2.16
11.9
4.5
—
—
—
0
0
6
16
4.11
2.00
1.2
1.1
—
—
—
0
0
6
16
4.11
2.00
2.3
1.6
15.67
19.81
ng/l
—
6
16
7
22
3.52
1.96
22.7
10.4
22.71
25.08
mmol/l
—
7
22
18
100
2.25
1.84
11.2
5.4
—
—
—
0
0
6
19
3.44
1.72
1.7
1.1
—
—
—
0
0
7
26
2.96
1.65
11.4
5.5
1.21
1.23
mmol/l
—
7
19
11
53
2.38
1.52
3.7
1.5
887.00
1324.00
nmol/l
0.64
11
36
38
298
2.15
1.46
33.2
8.1
119.71
92.72
u/l
1.25
38
276
11
55
2.28
1.40
1.5
1.2
—
—
—
0
0
30
371
0.52
1.33
34.2
19.2
13.90
13.47
%
0.56
30
371
10
49
2.30
1.32
1.3
1.3
—
—
—
0
0
6
26
2.48
1.22
2.3
1.7
—
—
—
0
0
10
51
2.20
1.21
13.8
15.3
25.53
24.77
mmol/l
—
10
51
27
198
1.79
1.17
5.9
3.0
—
—
estimate
—
0
0
14
84
1.93
1.12
3.4
1.5
—
—
—
0
0
12
68
2.01
1.12
3.5
1.7
—
—
—
0
0
11
61
2.03
1.09
3.6
1.8
174.18
85.80
ug/g
0.65
11
44
7
34
2.23
1.08
1.6
1.2
—
—
—
0
0
21
277
0.58
1.02
3.9
3.7
—
—
—
0
0
12
71
1.91
0.99
6.8
2.9
502.17
532.74
mosm/kgh2o
0.21
12
61
6
32
1.99
0.85
8.3
10.4
112.33
122.75
g/l
—
6
32
11
165
0.57
0.82
4.4
3.0
—
—
—
0
0
27
216
1.54
0.73
5.7
3.6
0.00
0.00
estimate
—
5
40
27
217
1.53
0.70
5.7
3.7
0.00
0.00
estimate
—
5
39
5
27
1.94
0.70
1.2
1.4
—
156.31
—
0
13
7
43
1.73
0.70
24.3
8.2
0.41
1.08
mmol/l
—
7
36
21
160
1.54
0.70
5.8
3.1
0.00
0.00
estimate
—
5
32
5
28
1.87
0.68
1.6
1.3
—
—
—
0
0
27
219
1.51
0.66
5.7
3.7
0.00
0.00
estimate
—
5
38
42
378
1.69
0.65
52.7
19.0
331.10
333.92
g/l
0.96
42
378
0
19
0.00
0.62
0.0
2.5
—
7.48
—
0
9
40
358
1.59
0.57
19.9
5.7
43.98
38.05
mmol/mol
1.49
40
340
17
129
1.48
0.56
1.8
1.5
—
—
—
0
0
26
218
1.40
0.49
16.0
11.7
0.00
0.00
e9/l
0.48
16
170
15
114
1.45
0.48
7.5
3.9
7.40
7.40
ph
—
10
76
19
154
1.38
0.43
2.3
2.0
—
—
—
0
0
0
15
0.00
0.42
0.0
11.9
—
—
—
0
0
16
131
1.33
0.32
5.1
3.4
76.18
25.28
ng/l
0.61
11
81
22
194
1.24
0.24
25.6
9.0
1.21
1.23
mmol/l
0.41
22
180
0
10
0.00
0.21
0.0
3.2
—
22.10
—
0
10
0
10
0.00
0.21
0.0
4.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
5.3
—
332.29
—
0
14
6
51
1.20
0.20
5.5
1.5
—
—
—
0
0
11
92
1.25
0.18
3.5
4.6
1.76
1.71
ug/l
0.02
11
82
12
102
1.23
0.17
3.1
1.8
—
—
—
0
0
6
79
0.73
0.17
4.5
1.6
—
—
—
0
0
5
46
1.10
0.10
1.4
1.2
—
—
—
0
0
39
382
1.10
0.03
6.7
5.3
1.96
1.97
mu/l
0.02
39
355
15
144
1.06
0.01
4.7
5.5
—
—
—
0
0
11
113
0.97
0.00
7.2
3.2
0.00
0.00
estimate
—
5
35
38
383
0.97
0.00
9.4
4.5
6.63
5.79
mmol/l
1.25
38
348
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
239.50
—
0
6
0
5
0.00
-0.00
0.0
10.0
—
884.80
—
0
5
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
1.19
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
128.38
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
11.2
—
1361.00
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
104.60
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
1475.00
—
0
5
0
5
0.00
-0.00
0.0
8.4
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: Z21_NEED_IMMUNI_OTH_SINGLE_INFECTIOUS_DISEA – Need for immunization against other single infectious diseases

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).