Benign neoplasm: Connective and other soft tissue of pelvis

CD2_BENIGN_CONNSOFT_PELVIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D21.5&
  • Hospital discharge: ICD-9 2156
  • Cause of death: ICD-10 D21.5&
  • Cause of death: ICD-9 2156

2 out of 7 registries used, show all original rules.

102

4. Check minimum number of events

None

102

5. Include endpoints

None

102

6. Filter based on genotype QC (FinnGen only)

95

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D21
Name in latin
Neoplasma benignum textus connectivi pelvis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 614 406 205
Only index persons 554 380 174
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 45.09 45.18 44.60
Only index persons 43.82 44.74 41.82

-FinnGen-

Key figures

All Female Male
Number of individuals 95 68 27
Unadjusted period prevalence (%) 0.02 0.02 0.01
Median age at first event (years) 46.87 47.17 46.12

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
96
Matched controls
960
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D21.5
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of pelvis
+∞
119.1
88
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
8.4
9.1
20
29
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
4.4
6.4
18
48

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
58
335
2.85
5.85
2.6
2.1
—
—
—
0
0
20
78
2.98
4.03
1.6
1.3
—
—
—
0
0
45
264
2.33
3.95
2.8
2.6
—
—
—
0
0
51
319
2.28
3.81
9.7
10.9
1.10
1.14
inr
0.28
45
257
19
78
2.79
3.48
2.3
4.7
2.49
11.43
ug/l
1.73
14
67
20
98
2.31
2.54
1.9
1.3
—
—
—
0
0
5
9
5.79
2.24
1.0
1.1
—
—
—
0
0
5
9
5.79
2.24
1.4
1.4
—
—
—
0
0
5
9
5.79
2.24
1.0
1.6
—
—
—
0
0
13
55
2.58
2.23
4.0
6.1
71.61
72.26
ng/l
0.02
13
48
41
275
1.86
2.23
9.7
6.8
—
—
—
0
0
89
787
2.79
2.20
5.3
5.5
1.75
1.85
mu/l
0.39
83
733
21
114
2.08
2.08
1.2
1.3
—
—
—
0
0
7
21
3.51
2.00
1.0
1.3
—
—
—
0
0
58
444
1.77
1.96
10.5
7.5
0.20
0.17
e9/l
0.52
52
392
18
96
2.08
1.86
4.9
9.4
105.22
104.32
mmol/l
0.47
18
96
59
459
1.74
1.84
4.9
5.3
6.35
6.41
mmol/l
0.10
54
429
30
193
1.81
1.81
4.9
4.0
1.02
1.02
kg/l
0.26
19
125
47
347
1.69
1.74
2.3
1.9
95.41
99.23
pmol/l
0.16
26
170
31
204
1.77
1.73
3.1
2.1
3.43
2.92
mg/l
0.46
26
181
23
138
1.88
1.72
2.3
3.3
42.08
173.22
ng/l
0.86
13
91
44
322
1.68
1.67
6.1
4.2
22.59
43.88
e6/l
0.84
34
217
58
457
1.68
1.65
4.9
3.9
0.00
0.00
estimate
-0.00
12
92
6
20
3.13
1.61
2.7
3.0
12.17
50.63
u/ml
—
6
20
51
391
1.65
1.60
3.2
3.1
—
—
estimate
—
0
0
52
402
1.64
1.57
10.9
7.2
0.75
0.66
%
0.37
45
377
34
236
1.68
1.55
2.7
3.5
—
—
—
0
0
56
442
1.64
1.55
10.6
7.3
1.80
1.90
e9/l
0.36
51
396
53
415
1.62
1.50
10.8
7.2
27.25
28.59
%
0.36
46
399
54
426
1.61
1.47
10.8
7.3
0.58
0.57
e9/l
0.05
46
372
6
22
2.84
1.46
1.2
1.3
—
—
—
0
0
32
223
1.65
1.43
1.9
1.6
23.84
20.74
nmol/l
0.45
27
184
54
429
1.59
1.41
10.8
7.2
0.04
0.04
e9/l
0.61
46
373
14
76
1.99
1.38
1.7
2.9
0.24
0.21
g/l
0.60
14
71
51
404
1.56
1.32
11.1
7.1
2.80
2.58
%
0.27
44
382
39
291
1.57
1.30
2.9
3.7
31.29
32.19
ng/l
0.02
23
175
33
240
1.57
1.22
4.7
2.9
—
—
—
0
0
89
823
2.12
1.21
23.5
14.8
18.94
20.23
mg/l
0.19
80
655
51
410
1.52
1.20
11.0
7.0
57.35
57.14
%
0.03
44
395
58
481
1.52
1.16
14.5
12.0
4.17
3.94
e9/l
0.32
50
418
7
30
2.44
1.15
3.6
2.0
—
—
—
0
0
46
365
1.50
1.13
4.2
3.4
6.35
6.17
ph
0.52
26
197
43
337
1.50
1.12
5.0
3.7
0.30
0.00
estimate
—
10
82
8
41
2.04
1.11
1.0
1.8
—
—
—
0
0
56
464
1.50
1.11
5.0
4.0
0.00
0.00
estimate
-0.00
12
91
5
21
2.45
1.10
1.0
2.0
—
—
—
0
0
83
752
1.77
1.08
6.0
5.6
38.52
38.45
mmol/mol
0.02
75
711
19
124
1.66
1.07
3.4
2.4
13.26
13.12
umol/l
0.03
19
116
50
408
1.47
1.05
11.2
7.3
8.63
8.62
%
0.01
43
387
48
389
1.47
1.04
12.6
11.8
0.00
0.00
e9/l
0.03
40
311
6
27
2.30
0.95
4.7
10.9
—
—
—
0
0
25
180
1.53
0.95
1.4
1.4
1.15
9.68
u/ml
—
6
79
45
367
1.43
0.91
1.8
1.9
1.42
1.37
mmol/l
0.16
40
316
8
42
1.99
0.91
1.0
1.7
—
—
—
0
0
18
121
1.60
0.91
2.2
2.2
—
—
—
0
0
54
456
1.42
0.90
4.9
3.9
0.00
0.00
estimate
-0.00
11
94
8
43
1.94
0.90
1.0
1.7
—
—
—
0
0
8
43
1.94
0.90
1.0
1.7
—
—
—
0
0
17
113
1.61
0.90
1.7
2.1
28.71
28.46
s
0.12
17
108
8
46
1.81
0.85
1.0
1.1
—
—
—
0
0
15
98
1.63
0.84
4.8
1.6
—
—
—
0
0
6
33
1.87
0.80
1.0
1.8
—
—
—
0
0
17
117
1.55
0.78
3.2
2.3
2.56
2.37
g/l
0.66
17
106
5
23
2.24
0.77
3.2
6.9
—
—
—
0
0
5
23
2.24
0.77
6.0
12.7
22.46
24.42
mmol/l
—
5
23
26
197
1.44
0.77
7.9
4.7
—
—
—
0
0
9
56
1.67
0.75
1.9
1.5
—
—
—
0
0
5
25
2.05
0.74
3.8
1.9
—
—
—
0
0
7
40
1.81
0.73
1.0
1.7
—
—
—
0
0
12
77
1.64
0.72
5.0
6.4
7.37
7.39
ph
—
6
44
13
86
1.59
0.70
6.5
8.1
7.43
7.41
ph
—
7
53
5
27
1.90
0.69
1.8
1.9
1.18
1.15
g/l
—
5
27
25
193
1.40
0.67
1.4
1.9
0.43
1.42
mg/l
1.90
17
156
90
855
1.84
0.66
16.8
12.8
—
—
—
0
0
5
29
1.76
0.64
1.0
1.7
—
—
—
0
0
31
256
1.31
0.54
4.3
3.1
0.00
0.01
estimate
—
10
81
31
256
1.31
0.54
1.2
1.3
0.51
1.65
u/ml
—
8
62
7
45
1.60
0.50
1.0
1.1
—
0.48
—
0
6
7
45
1.60
0.50
1.0
1.2
0.89
0.81
g/l
—
7
45
7
45
1.60
0.50
1.0
1.1
1.71
1.56
g/l
—
7
45
10
68
1.53
0.49
8.0
11.1
—
—
—
0
0
7
50
1.43
0.46
7.9
4.8
25.33
23.52
mmol/l
—
7
50
18
141
1.34
0.44
3.7
3.2
8.00
3.62
e6/l
—
10
67
8
58
1.41
0.43
7.8
10.7
25.24
24.56
mmol/l
—
8
58
0
15
0.00
0.41
0.0
3.4
—
—
—
0
0
0
17
0.00
0.41
0.0
4.1
—
—
—
0
0
28
237
1.26
0.40
2.3
1.4
2.22
2.45
g/l
0.23
15
150
5
36
1.41
0.39
2.2
2.4
—
—
—
0
0
23
191
1.27
0.38
1.4
1.4
10.90
19.25
iu/ml
—
6
58
31
268
1.23
0.37
11.3
6.3
—
—
—
0
0
6
43
1.42
0.36
2.8
4.0
—
—
—
0
0
28
241
1.23
0.34
5.7
4.2
0.00
0.00
estimate
-0.00
11
91
25
214
1.23
0.32
1.8
2.1
—
—
—
0
0
14
111
1.31
0.32
3.9
2.4
20.44
22.47
%
0.32
14
103
75
714
1.23
0.31
29.7
19.0
332.33
331.94
g/l
0.13
75
714
31
349
0.83
0.30
3.2
3.0
—
—
—
0
0
12
94
1.32
0.30
1.2
1.4
—
—
—
0
0
10
77
1.33
0.27
1.4
1.6
—
—
—
0
0
10
77
1.33
0.27
5.4
3.5
—
—
—
0
0
14
116
1.24
0.23
1.9
1.2
—
—
—
0
0
13
107
1.25
0.23
1.4
1.4
—
—
—
0
0
5
41
1.23
0.22
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
0.08
—
0
5
28
252
1.16
0.21
3.8
4.1
1.72
75.49
mg/mmol
0.53
19
158
0
13
0.00
0.21
0.0
2.9
—
—
—
0
0
0
13
0.00
0.21
0.0
4.1
—
31.54
—
0
13
0
14
0.00
0.20
0.0
3.8
—
0.93
—
0
8
7
58
1.22
0.18
1.4
1.1
—
—
—
0
0
8
96
0.82
0.14
1.0
1.1
—
—
—
0
0
8
99
0.79
0.14
1.9
1.3
—
—
—
0
0
21
190
1.13
0.14
1.5
1.7
—
—
—
0
0
28
260
1.11
0.12
10.2
4.3
7.39
7.40
ph
0.61
19
183
5
48
1.04
0.09
7.0
12.1
94.66
95.17
%
—
5
48
6
57
1.06
0.08
1.2
1.2
—
—
—
0
0
12
127
0.94
0.02
1.5
1.5
—
—
—
0
0
13
128
1.02
0.00
1.8
1.7
—
—
—
0
0
21
208
1.01
0.00
4.7
7.0
—
—
—
0
0
13
133
0.97
0.00
2.2
1.6
—
—
—
0
0
27
269
1.01
0.00
1.8
1.6
—
—
—
0
0
25
249
1.01
0.00
4.0
3.4
15.71
32.55
mg/l
1.03
16
157
10
99
1.01
0.00
2.3
1.8
—
—
—
0
0
13
131
0.99
0.00
1.8
1.5
493.33
600.00
titre
—
6
30
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
15.6
—
1485.44
—
0
9
0
8
0.00
-0.00
0.0
3.6
—
106.75
—
0
8
0
5
0.00
-0.00
0.0
1.4
—
15.98
—
0
5
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
5
49
1.02
-0.00
7.0
11.6
0.74
0.62
%
—
5
49
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
11.0
—
0.56
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.8
—
—
—
0
0
5
56
0.89
-0.00
1.4
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
97
0.92
-0.00
4.3
2.9
0.60
0.86
ug/l
—
9
55
0
9
0.00
-0.00
0.0
12.3
—
846.00
—
0
9
0
8
0.00
-0.00
0.0
3.6
—
1.21
—
0
8
0
8
0.00
-0.00
0.0
3.6
—
4.09
—
0
8
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
105.44
—
0
9
5
50
1.00
-0.00
7.0
11.6
2.14
1.27
%
—
5
50
0
5
0.00
-0.00
0.0
1.0
—
140.20
—
0
5
0
5
0.00
-0.00
0.0
3.6
—
32.20
—
0
5
0
9
0.00
-0.00
0.0
1.4
—
6.12
—
0
9
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_CONNSOFT_PELVIS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_CONNSOFT_PELVIS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: CD2_BENIGN_CONNSOFT_PELVIS – Benign neoplasm: Connective and other soft tissue of pelvis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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