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Deformity of finger(s)

EFO MESH Endpoint Browser PheWeb

M13_FINGERDEFORM

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

255

4. Check minimum number of events

None

255

5. Include endpoints

None

255

6. Filter based on genotype QC (FinnGen only)

229

Control definitions (FinnGen only)

Control exclude
M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1492 854 627
Only index persons 1395 803 592
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.03 0.03 0.02
Median age at first event (years)
Whole population 50.52 50.87 49.88
Only index persons 50.09 50.51 49.51

-FinnGen-

Key figures

All Female Male
Number of individuals 229 134 95
Unadjusted period prevalence (%) 0.05 0.05 0.04
Median age at first event (years) 53.24 52.12 54.83

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
238
Matched controls
2380
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M20.00
ICD-10 Finland
Buttonhole deformity of fingers
+∞
138.5
119
*
M20.1
ICD-10 Finland
Hallux valgus (acquired)
44.1
84.4
52
15
M20.01
ICD-10 Finland
Swan neck deformity of fingers
+∞
65.7
60
*
M19.0
ICD-10 Finland
Primary arthrosis of other joints
26.8
61.1
44
20
M20.08
ICD-10 Finland
Deformity of finger(s)
+∞
56.5
52
*
M17.1
ICD-10 Finland
Other primary gonarthrosis
14.0
44.2
44
38
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
13.1
37.2
38
34
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
12.4
36.7
39
37
M25.5
ICD-10 Finland
Pain in joint
4.9
30.1
95
286
A07EC01
ATC
sulfasalazine; oral, rectal
12.1
28.3
30
28
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
10.7
26.8
31
33
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
6.9
25.5
44
76
NHK30
NOMESCO Finland
Osteotomy or rotation osteotomy of first metatarsal or tarsal bone
+∞
25.5
24
*
L04AX03
ATC
methotrexate; systemic
9.5
24.6
31
37
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
+∞
24.4
23
*
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
75.7
24.4
27
*
R4120
NOMESCO Finland
Occupational therapy
8.3
24.0
34
47
NDU20
NOMESCO Finland
Removal of internal fixation device from wrist or hand
36.4
23.0
29
9
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
229.2
20.9
21
*
M16.1
ICD-10 Finland
Other primary coxarthrosis
23.4
20.5
29
14
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
+∞
20.1
19
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
7.3
19.7
31
48
NHG70
NOMESCO Finland
Arthroplasty of first tarsometatarsal joint
+∞
19.0
18
*
P01BA02
ATC
hydroxychloroquine; oral
18.2
18.9
29
18
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
102.8
17.8
19
*
NF1AA
NOMESCO Finland
Hip X-ray examination
7.6
17.3
26
38
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
36.2
16.0
20
6
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
+∞
15.8
15
*
NDG76
NOMESCO Finland
Fusion of DIP joint
+∞
15.8
15
*
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
+∞
15.8
15
*
S66.3
ICD-10 Finland
Injury of extensor muscle and tendon of other finger at wrist and hand level
17.6
15.6
24
15
M20.2
ICD-10 Finland
Hallux rigidus
60.7
15.0
17
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
27.1
14.9
20
8
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
+∞
14.7
14
*
L88
ICPC
Rheumatoid/seropositive arthritis
32.3
14.1
18
6
WX320
NOMESCO Finland
Spinalanesthesy
3.3
13.8
63
232
M79.6
ICD-10 Finland
Pain in limb
2.8
13.2
117
618
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.8
12.6
30
69
M01AX05
ATC
glucosamine; oral
3.8
12.2
41
123
N02AJ06
ATC
codeine and paracetamol; systemic
2.6
12.1
112
599
M01AH05
ATC
etoricoxib; oral
2.7
11.9
155
976
N02AX02
ATC
tramadol; systemic, rectal
2.6
11.6
112
609
73799
ICD-8 Finland
Hallux valgus and varus
+∞
11.5
11
*
L04AA13
ATC
[U] leflunomide
125.8
11.5
12
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.6
11.5
110
594
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
4.3
10.9
30
77
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.8
10.8
71
317
NDL99
NOMESCO Finland
Other operation on muscle or tendon of wrist or hand
62.9
10.7
12
*
L15
ICPC
Knee symptom/complaint
2.9
10.6
61
253
TQW40
NOMESCO Finland
Remowal of suture of skin
4.4
10.6
28
70
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
114.9
10.5
11
*
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
+∞
10.5
10
*
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
+∞
10.5
10
*
X59
ICD-10 Finland
Exposure to unspecified factor
3.1
10.5
52
199
L01BA01
ATC
methotrexate; systemic
34.2
10.4
13
*
N03AX12
ATC
[U] gabapentin; oral
3.2
10.4
47
170
X58
ICD-10 Finland
Exposure to other specified factors
3.1
10.4
49
182
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.7
10.3
36
110
H02AB06
ATC
prednisolone; systemic
2.4
10.3
121
710
N03AX16
ATC
[U] pregabalin
2.8
10.1
62
266
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
5.1
10.0
22
47
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
27.3
9.9
13
5
NH3EA
NOMESCO Finland
Feet X-ray examination with load
57.4
9.7
11
*
L13
ICPC
Hip symptom/complaint
3.0
9.6
49
190
M54.5
ICD-10 Finland
Low back pain
2.4
9.6
97
529
L04AB04
ATC
adalimumab; parenteral
18.5
9.5
14
8
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
31.4
9.5
12
*
T92.3
ICD-10 Finland
Sequelae of dislocation, sprain and strain of upper limb
104.0
9.5
10
*
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
+∞
9.4
9
*
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.5
9.3
72
346
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
38.3
9.1
11
*
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.7
9.1
22
51
ZXA05
NOMESCO Finland
Left side
2.6
8.9
62
282
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.4
8.8
83
435
SPAT1149
SPAT
Suture or treatment of traumatic wound
3.0
8.8
43
162
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
51.9
8.7
10
*
L08
ICPC
Shoulder symptom/complaint
2.6
8.7
62
285
B01AB05
ATC
enoxaparin; parenteral
2.4
8.7
75
378
L12
ICPC
Hand/finger symptom/complaint
2.7
8.6
52
220
S18
ICPC
Laceration/cut
2.2
8.4
121
754
M24.4
ICD-10 Finland
Recurrent dislocation and subluxation of joint
+∞
8.4
8
*
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
+∞
8.4
8
*
7362A
ICD-9 Finland
Other acquired deformities of limbs, Other acquired deformities of finger[DEFORMATIO BOUTONNIôRE]
+∞
8.4
8
*
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
15.2
8.3
13
9
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.0
8.1
39
146
R29
ICPC
Respiratory symptom/complaint other
3.8
7.9
25
71
NF1DA
NOMESCO Finland
X-ray of hips
46.5
7.8
9
*
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
46.5
7.8
9
*
T92.5
ICD-10 Finland
Sequelae of injury of muscle and tendon of upper limb
46.5
7.8
9
*
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
46.5
7.8
9
*
M01AH01
ATC
celecoxib; oral
2.9
7.8
40
155
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.8
7.6
41
163
ZXA00
NOMESCO Finland
Right side
2.4
7.6
64
317
S63.6
ICD-10 Finland
Sprain and strain of finger(s)
6.9
7.6
18
28
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.3
7.6
76
406
L04AX01
ATC
azathioprine; systemic
6.4
7.6
19
32
WX702
NOMESCO Finland
Supraglottic ventilation device
3.9
7.5
23
64
N06AX21
ATC
duloxetine; oral
3.0
7.4
35
129
NDL32
NOMESCO Finland
Suture or reinsertion of tendon of wrist or hand, extensor tendon
11.4
7.4
13
12
SPAT1153
SPAT
Removal of sutures
2.2
7.4
78
425
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
3.9
7.4
22
60
M65.3
ICD-10 Finland
Trigger finger
4.6
7.4
18
42
W22
ICD-10 Finland
Striking against or struck by other object(s)
3.6
7.3
25
75
M19.2
ICD-10 Finland
Other secondary arthrosis
+∞
7.3
7
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
7.3
60
293
L90
ICPC
Osteoarthrosis of knee
8.3
7.2
15
19
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
9.2
7.2
14
16
L17
ICPC
Foot/toe symptom/complaint
2.2
7.2
77
422
M70.6
ICD-10 Finland
Trochanteric bursitis
2.9
7.0
35
133
S63.4
ICD-10 Finland
Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
14.3
7.0
11
8
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
6.9
120
788
S61.0
ICD-10 Finland
Open wound of finger(s) without damage to nail
3.0
6.8
33
123
N06AA09
ATC
amitriptyline; systemic
3.3
6.7
27
90
NDM99
NOMESCO Finland
Other operation on fascia, ganglion, synovial sheath or bursa of wrist or hand
23.3
6.7
9
*
L72.1
ICD-10 Finland
Trichilemmal cyst
3.3
6.7
26
85
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.1
6.7
98
603
M01AX17
ATC
nimesulide; oral
2.3
6.6
57
283
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
9.1
6.6
13
15
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
9.1
6.6
13
15
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
9.1
6.6
13
15
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
5.6
6.6
18
34
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.2
6.5
27
92
NG1DA
NOMESCO Finland
X-ray of knees
71.7
6.5
7
*
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
71.7
6.5
7
*
NDL66
NOMESCO Finland
Transposition of tendon of wrist or hand, other tendon
71.7
6.5
7
*
NHL99
NOMESCO Finland
Other operation on muscle or tendon of ankle or foot
71.7
6.5
7
*
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
71.7
6.5
7
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
6.4
60
309
M01AE03
ATC
ketoprofen; systemic, rectal
2.1
6.4
89
535
J01CF02
ATC
cloxacillin; systemic
11.5
6.4
11
10
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
18.6
6.3
9
5
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
+∞
6.3
6
*
NDG60
NOMESCO Finland
Arthroplasty of first CMC joint
+∞
6.3
6
*
NDL62
NOMESCO Finland
Shortening of tendon of hand
+∞
6.3
6
*
M07.3
ICD-10 Finland
Other psoriatic arthropathies
+∞
6.3
6
*
L04AB01
ATC
etanercept; parenteral
+∞
6.3
6
*
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
+∞
6.3
6
*
C05AA08
ATC
fluocortolone; rectal, topical
2.6
6.3
38
160
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
6.6
6.3
15
24
NFB40
NOMESCO Finland
Primary total prosthetic replacement of hip joint using hybrid technique
27.5
6.3
8
*
D07AD01
ATC
clobetasol; topical
2.5
6.2
44
200
M13.9
ICD-10 Finland
Arthritis, unspecified
8.0
6.2
13
17
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
7.0
6.1
14
21

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
149
1017
2.24
8.21
9.3
5.4
0.04
0.04
e9/l
0.40
137
845
149
1017
2.24
8.21
9.2
5.4
0.61
0.58
e9/l
0.68
138
843
81
434
2.31
8.08
2.6
2.7
333.40
343.79
umol/l
0.47
72
389
62
297
2.47
7.93
1.4
1.2
50.38
14.30
iu/ml
1.08
27
91
150
1036
2.21
7.90
9.3
5.4
1.83
2.09
e9/l
0.96
140
891
152
1056
2.22
7.88
9.4
5.9
0.18
0.18
e9/l
0.09
142
897
107
651
2.17
7.76
8.4
5.3
—
—
—
0
0
55
254
2.52
7.58
1.4
1.1
23.60
1.47
u/ml
0.59
18
100
55
255
2.50
7.51
2.0
1.9
—
—
—
0
0
130
868
2.10
7.24
3.0
2.6
—
—
estimate
—
0
0
135
933
2.03
6.64
9.6
5.5
0.62
0.68
%
0.73
127
860
135
935
2.03
6.58
9.6
5.5
2.66
2.78
%
0.25
128
873
134
936
1.99
6.26
9.7
5.4
57.81
57.65
%
0.05
128
892
136
955
1.99
6.26
9.6
5.6
27.17
27.49
%
0.12
130
904
134
939
1.98
6.17
9.9
5.6
8.98
8.79
%
0.33
128
874
45
214
2.36
5.74
1.8
1.2
342.86
385.31
titre
0.09
14
49
141
1026
1.92
5.60
6.4
7.9
1.22
1.21
mmol/l
0.27
126
893
126
903
1.84
5.06
6.1
7.0
1.22
1.21
mmol/l
0.33
118
830
153
1168
1.87
4.98
11.6
10.5
4.25
4.18
e9/l
0.15
145
995
127
917
1.83
4.94
19.8
11.3
1.29
1.21
inr
0.72
102
768
46
244
2.10
4.47
3.6
2.3
109.78
112.41
ug/g
0.04
40
198
70
431
1.88
4.46
1.8
1.5
1.53
1.14
mg/l
0.45
54
335
34
160
2.31
4.42
2.6
2.3
0.00
0.14
estimate
—
8
36
190
1586
1.98
4.35
4.5
4.2
15.19
14.81
pmol/l
0.85
176
1453
106
748
1.75
4.27
4.8
3.6
35.68
35.96
ng/l
0.01
78
536
122
900
1.73
4.17
6.0
5.0
35.80
35.68
g/l
0.08
114
848
150
1176
1.75
4.08
5.5
5.3
6.85
6.70
mmol/l
0.26
144
1111
41
216
2.09
4.04
1.4
1.6
—
—
—
0
0
36
183
2.14
3.89
1.5
3.1
82.09
70.98
e9/l
0.92
25
134
7
8
8.97
3.80
1.6
1.0
—
—
—
0
0
64
403
1.80
3.73
1.4
1.6
2.13
2.38
g/l
0.81
40
249
137
1069
1.66
3.60
5.9
3.6
0.00
0.00
estimate
-0.00
30
200
76
508
1.73
3.60
2.8
1.9
2.49
2.77
mg/l
0.58
67
432
220
1978
2.48
3.57
23.2
14.6
22.90
25.66
mg/l
0.53
196
1573
183
1548
1.79
3.51
11.5
8.5
76.99
78.90
u/l
0.32
178
1460
38
207
1.99
3.42
3.8
3.7
7.38
7.39
ph
0.34
19
123
91
651
1.64
3.29
3.2
2.4
55.82
72.03
u/l
0.79
84
602
83
581
1.66
3.27
3.7
2.1
191.54
194.97
u/l
0.02
76
556
134
1057
1.61
3.24
5.8
3.5
40.81
0.00
estimate
0.49
32
219
111
837
1.61
3.24
5.6
3.2
6.36
6.22
ph
0.76
68
486
23
105
2.32
3.21
2.9
2.9
0.61
0.62
%
0.09
23
105
212
1895
2.09
3.21
6.1
5.1
1.92
1.94
mu/l
0.11
197
1744
87
620
1.64
3.18
2.9
2.3
—
—
—
0
0
10
25
4.13
3.12
1.4
1.4
16.94
31.37
ng/l
—
10
25
117
900
1.59
3.10
2.1
2.1
95.20
96.05
pmol/l
0.07
62
474
23
107
2.27
3.08
3.0
2.9
1.43
1.20
%
0.35
23
107
29
149
2.08
3.06
1.1
1.2
—
—
—
0
0
60
394
1.70
2.97
1.6
1.8
224490188.63
34925820.56
pmol/l
0.39
49
335
132
1052
1.57
2.95
5.9
3.5
0.00
0.00
estimate
-0.00
29
218
81
576
1.62
2.95
5.9
3.7
0.00
0.00
estimate
-0.00
26
207
84
609
1.59
2.80
7.4
6.6
—
—
—
0
0
38
224
1.83
2.71
3.8
4.0
4.23
7.81
e9/l
0.80
28
199
65
446
1.63
2.71
3.2
2.5
4.69
6.84
e6/l
0.55
59
404
122
968
1.53
2.70
3.4
2.8
130.04
124.80
ug/l
0.08
112
899
226
2097
2.54
2.68
17.8
13.0
—
—
—
0
0
32
180
1.90
2.64
5.8
10.1
—
—
—
0
0
31
173
1.91
2.61
3.6
3.1
4.53
4.58
kpa
0.03
31
167
57
382
1.65
2.60
3.0
2.6
509.04
528.94
mosm/kgh2o
0.25
48
334
104
803
1.52
2.58
5.9
3.5
0.08
0.00
estimate
0.49
25
181
67
473
1.58
2.46
1.3
1.3
3.70
1.25
u/ml
0.34
16
144
35
208
1.80
2.44
4.1
3.6
5.89
5.82
kpa
0.16
35
203
18
84
2.24
2.42
2.8
2.5
0.00
0.04
estimate
—
7
26
44
281
1.69
2.40
1.1
1.2
—
—
—
0
0
21
105
2.10
2.39
1.2
1.1
—
—
—
0
0
39
243
1.72
2.32
1.5
1.3
—
—
—
0
0
80
596
1.52
2.30
1.9
1.6
21.26
20.94
nmol/l
0.07
66
502
45
293
1.66
2.28
1.5
1.6
—
—
—
0
0
79
588
1.51
2.27
4.0
3.0
—
—
—
0
0
16
74
2.25
2.20
1.1
1.1
—
—
—
0
0
31
185
1.78
2.14
2.8
4.6
7.40
7.38
ph
0.56
21
134
26
147
1.86
2.13
1.2
1.4
—
—
—
0
0
11
44
2.57
2.04
1.2
1.1
—
—
—
0
0
132
1105
1.44
2.02
6.8
7.4
9.45
11.55
umol/l
3.36
125
1058
74
558
1.47
1.97
5.2
4.3
—
—
—
0
0
113
931
1.41
1.84
12.5
10.2
0.00
0.00
e9/l
0.42
101
741
62
459
1.47
1.79
7.1
5.2
—
—
—
0
0
48
339
1.52
1.74
1.8
1.9
—
—
—
0
0
63
471
1.46
1.73
7.3
3.6
1.02
1.02
kg/l
0.65
46
309
18
97
1.93
1.71
2.7
2.4
—
—
—
0
0
12
55
2.24
1.70
1.9
3.0
1.00
3.93
index
—
7
30
228
2170
2.21
1.70
28.7
19.0
77.88
77.42
umol/l
0.07
228
2138
36
240
1.59
1.67
3.4
2.6
10.89
8.04
umol/l
0.24
30
215
6
19
3.21
1.67
1.7
1.4
—
—
—
0
0
11
50
2.26
1.59
1.0
1.1
—
—
—
0
0
5
15
3.38
1.53
1.4
1.3
—
—
—
0
0
74
582
1.39
1.53
3.9
2.9
0.21
0.56
e6/l
1.01
62
407
11
51
2.21
1.53
1.1
1.1
—
—
—
0
0
74
585
1.38
1.48
3.7
2.9
0.00
0.00
estimate
-0.00
22
168
91
746
1.36
1.45
4.9
3.6
26.85
99.70
e6/l
1.85
75
519
157
1398
1.36
1.44
4.0
3.1
50.53
45.44
u/l
0.49
146
1321
6
22
2.77
1.44
3.7
2.9
4.17
4.04
mmol/l
—
6
22
6
22
2.77
1.44
3.7
2.9
1.21
1.21
mmol/l
—
6
22
6
22
2.77
1.44
3.7
2.9
105.67
105.64
mmol/l
—
6
22
6
22
2.77
1.44
1.7
2.2
3.03
0.64
mmol/l
—
6
22
24
151
1.66
1.41
2.2
2.4
6.36
6.12
ph
0.68
14
103
15
82
1.89
1.39
3.2
1.8
—
—
—
0
0
207
1938
1.52
1.38
4.8
4.2
1.25
1.28
mmol/l
0.29
193
1788
77
622
1.35
1.33
4.7
4.4
7.40
7.40
ph
0.71
57
440
17
99
1.77
1.31
1.5
1.2
—
—
—
0
0
5
18
2.81
1.29
1.4
2.4
75.40
131.71
ng/l
—
5
18
13
70
1.91
1.26
1.4
2.0
1432.08
283.47
ug/l
0.45
13
64
33
231
1.50
1.26
1.8
1.6
—
—
—
0
0
81
669
1.32
1.19
4.6
3.1
143.93
57.73
e6/l
0.30
72
496
8
38
2.14
1.19
1.1
1.2
—
—
—
0
0
218
2077
1.59
1.17
6.7
5.7
2.70
2.73
mmol/l
0.16
204
1937
98
833
1.30
1.17
2.0
2.1
—
—
—
0
0
5
20
2.53
1.15
1.2
1.1
—
—
—
0
0
207
1957
1.44
1.10
7.1
6.1
38.60
39.29
mmol/mol
0.65
195
1827
27
187
1.50
1.09
1.6
1.4
—
—
—
0
0
214
2038
1.50
1.07
5.7
4.9
1.47
1.47
mmol/l
0.07
201
1891
9
48
1.91
1.01
1.7
2.3
—
—
—
0
0
37
279
1.39
0.98
5.4
5.4
1.05
1.01
mmol/l
0.34
32
255
79
667
1.28
0.97
5.9
5.7
1.92
3.59
ug/l
1.64
70
603
214
2045
1.46
0.97
5.9
4.9
4.66
4.66
mmol/l
0.03
202
1915
7
37
1.92
0.95
1.3
1.2
—
—
—
0
0
10
55
1.85
0.93
1.2
1.0
—
120.00
—
0
5
22
153
1.48
0.89
6.1
3.6
—
—
—
0
0
11
64
1.75
0.87
3.3
5.2
34.65
42.35
mg/l
0.32
11
57
11
64
1.75
0.87
3.2
5.2
31.34
95.59
mg/l
0.70
11
58
73
850
0.80
0.86
3.1
3.3
—
—
—
0
0
14
89
1.61
0.83
2.7
3.1
—
—
—
0
0
19
131
1.49
0.81
1.4
1.2
—
—
—
0
0
18
123
1.50
0.80
2.8
3.2
4.91
5.09
kpa
0.39
18
118
0
25
0.00
0.79
0.0
2.8
—
—
—
0
0
0
25
0.00
0.79
0.0
2.4
—
1.46
—
0
14
7
38
1.87
0.74
1.0
1.0
—
—
—
0
0
18
127
1.45
0.70
3.9
4.0
—
—
—
0
0
7
42
1.69
0.69
1.7
1.6
—
—
—
0
0
15
207
0.71
0.60
1.3
1.4
—
—
—
0
0
8
53
1.53
0.59
4.1
4.6
—
—
—
0
0
79
701
1.19
0.59
2.2
4.1
2.35
2.36
mmol/l
0.40
69
633
97
877
1.18
0.58
2.0
1.9
1.36
1.35
mmol/l
0.03
81
722
28
222
1.30
0.57
1.6
1.6
—
—
—
0
0
10
66
1.54
0.53
8.3
9.7
—
—
—
0
0
6
39
1.55
0.53
3.3
1.7
—
—
—
0
0
6
40
1.51
0.52
1.2
2.9
34.07
28.89
umol/l
—
6
35
15
199
0.74
0.49
1.3
1.4
—
—
—
0
0
30
247
1.25
0.47
6.0
8.6
0.22
1.23
mmol/l
1.06
22
203
46
397
1.20
0.46
5.0
4.0
545.03
316.04
ng/l
0.29
33
306
24
193
1.27
0.45
2.3
2.1
387.21
384.24
nmol/l
0.02
24
182
18
140
1.31
0.43
1.0
1.2
138.52
177.02
u/ml
—
6
55
30
250
1.23
0.43
6.4
8.6
7.41
7.42
ph
0.14
17
145
206
2003
1.21
0.42
5.9
4.8
5.79
5.94
mmol/l
1.55
190
1852
39
335
1.20
0.42
4.3
2.7
2.02
1.98
e6/l
0.02
24
145
0
15
0.00
0.41
0.0
1.3
—
79.73
—
0
15
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
274.00
—
0
13
5
36
1.40
0.38
1.2
1.6
—
—
—
0
0
20
242
0.81
0.34
2.8
4.9
4.13
21.60
ug/l
1.00
14
213
6
44
1.37
0.34
1.0
1.0
—
—
—
0
0
12
91
1.34
0.34
1.5
1.7
0.22
0.25
mg/l
—
6
40
37
323
1.17
0.34
1.5
1.6
1039.75
1233.06
nmol/l
0.78
26
245
77
711
1.12
0.33
5.6
3.3
6.98
7.60
mmol/l
0.79
63
603
6
47
1.28
0.32
22.8
2.1
—
—
—
0
0
7
57
1.23
0.29
3.1
1.5
—
—
—
0
0
45
408
1.13
0.26
3.2
3.1
0.60
0.83
ug/l
2.21
32
270
9
72
1.26
0.26
2.1
2.9
—
—
—
0
0
20
170
1.19
0.25
1.1
1.8
—
—
—
0
0
18
211
0.84
0.24
1.2
1.4
—
—
—
0
0
73
684
1.10
0.24
4.5
4.2
4.23
8.67
mg/mmol
1.66
43
435
5
38
1.32
0.23
2.0
1.4
—
—
—
0
0
5
40
1.26
0.22
1.6
1.5
—
—
—
0
0
5
41
1.22
0.22
3.0
6.0
—
—
—
0
0
13
107
1.23
0.22
1.6
1.6
—
—
—
0
0
15
126
1.20
0.21
3.3
2.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
7.6
—
7.18
—
0
10
0
14
0.00
0.20
0.0
1.1
—
5.28
—
0
6
6
49
1.23
0.20
1.0
1.2
—
—
—
0
0
71
671
1.08
0.19
3.8
3.4
25.78
47.45
mg/l
1.49
36
433
28
253
1.12
0.18
1.3
1.5
—
—
—
0
0
63
595
1.08
0.17
1.4
1.4
—
—
—
0
0
8
71
1.13
0.16
2.9
1.5
—
—
—
0
0
10
83
1.21
0.15
1.5
1.3
—
—
—
0
0
5
44
1.14
0.10
1.0
1.2
27.41
15.59
u/l
—
5
36
7
68
1.03
0.08
3.1
1.5
—
—
—
0
0
8
76
1.05
0.07
1.3
1.7
—
10.08
—
0
17
9
100
0.90
0.06
1.0
1.1
—
—
—
0
0
27
284
0.94
0.06
1.2
1.3
—
—
—
0
0
16
152
1.06
0.02
3.9
3.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
26.25
—
0
8
7
77
0.91
0.00
1.0
1.1
1.62
1.57
g/l
—
7
77
0
8
0.00
0.00
0.0
6.8
—
40.13
—
0
8
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
7
71
0.99
-0.00
1.6
1.5
—
—
—
0
0
7
71
0.99
-0.00
3.1
1.5
—
—
—
0
0
6
59
1.02
-0.00
1.2
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.02
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
29.08
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
8.3
—
16.26
—
0
9
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
0.00
—
0
7
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
58
0.86
-0.00
1.4
1.2
4.20
9.21
u/l
—
5
46
0
7
0.00
-0.00
0.0
1.4
—
17.30
—
0
7
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
52
0.96
-0.00
1.0
1.2
—
—
—
0
0
7
71
0.99
-0.00
3.1
1.5
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint M13_FINGERDEFORM and mortality.

Females

Parameter HR [95% CI] p-value
M13_FINGERDEFORM 1.24 [0.96, 1.6] 0.096
Birth year 0.999 [0.99, 1.01] 0.752

During the follow-up period (1.1.1998 — 31.12.2019), 81 out of 690 females with M13_FINGERDEFORM died.

Males

Parameter HR [95% CI] p-value
M13_FINGERDEFORM 1.117 [0.87, 1.43] 0.381
Birth year 0.991 [0.98, 1.0] 0.189

During the follow-up period (1.1.1998 — 31.12.2019), 81 out of 494 males with M13_FINGERDEFORM died.

Mortality risk

Mortality risk for people of age

years, who have M13_FINGERDEFORM.

N-year risk Females Males
1 0.155% 0.254%
5 0.81% 1.674%
10 2.038% 3.989%
15 3.924% 7.081%
20 6.915% 11.933%

Relationships between endpoints

↥

Index endpoint: M13_FINGERDEFORM – Deformity of finger(s)

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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