No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
245 |
4. Check minimum number of eventsNone |
245 |
5. Include endpointsNone |
245 |
6. Filter based on genotype QC (FinnGen only) |
220 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D33
- Name in latin
- Neoplasma benignum cerebri non specificatum
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Brain, unspecified
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of brain and other parts of central nervous system
- Benign neoplasms
- Neoplasms
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2424 | 1453 | 938 |
| Only index persons | 1513 | 913 | 600 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.03 |
| Only index persons | 0.03 | 0.03 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 48.74 | 51.26 | 44.54 |
| Only index persons | 42.00 | 45.00 | 37.43 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 220 | 136 | 84 |
| Unadjusted period prevalence (%) | 0.04 | 0.05 | 0.04 |
| Median age at first event (years) | 42.31 | 41.21 | 44.09 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 228
- Matched controls
- 2280
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D33.2
ICD-10 Finland
Benign neoplasm: Brain, unspecified
+∞
128.7
111
*
22500
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Brain
+∞
75.3
68
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
11.5
65.5
85
112
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
14.1
60.5
63
60
2250A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Brain
+∞
60.1
55
*
2152
FHL
Extraction, big brain
+∞
38.6
36
*
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
58.4
33.8
39
8
N03AF02
ATC
oxcarbazepine; oral
12.0
32.4
35
34
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
38.8
31.2
39
12
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
34.1
27.2
35
12
N03AF01
ATC
carbamazepine; oral, rectal
7.1
25.2
42
70
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
33.0
22.5
29
10
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.2
21.2
50
116
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
30.4
20.6
27
10
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
8.9
20.5
27
34
G40.9
ICD-10 Finland
Epilepsy, unspecified
7.8
19.1
28
40
E23.00
ICD-10 Finland
Panhypopituitarism
109.1
18.9
20
*
101
Kela drug reimbursment
Anterior pituitary hypofunction
206.3
18.8
19
*
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
18.6
18.4
28
17
2252A
ICD-9 Finland
Benign neoplasm of brain and other parts of nervous system, Cerebral meninges
+∞
16.9
16
*
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
43.6
16.6
20
5
XCK00
NOMESCO Finland
Perimetry
5.3
16.0
35
75
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
16.3
15.8
25
17
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
13.2
15.0
26
22
N03AX14
ATC
levetiracetam; systemic
12.1
15.0
27
25
D33.30
ICD-10 Finland
Acoustic neuroma
38.8
14.7
18
5
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
148.5
13.6
14
*
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
20.6
13.2
19
10
H02AB09
ATC
hydrocortisone; systemic
12.0
12.9
23
21
N03AB02
ATC
phenytoin; systemic
13.5
12.4
21
17
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
21.4
11.3
16
8
H53.4
ICD-10 Finland
Visual field defects
12.1
11.3
20
18
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
45.7
11.0
13
*
23810
ICD-8 Finland
Neoplasm of unspecified nature of eye, brain and other parts of nervous system, Brain
115.1
10.5
11
*
G93.0
ICD-10 Finland
Cerebral cysts
115.1
10.5
11
*
22520
ICD-8 Finland
Benign neoplasm of brain and other parts of nervous system, Cerebral meninges
115.1
10.5
11
*
9380/3-C71.9
ICD-O-3
Glioma, malignant of brain, NOS
115.1
10.5
11
*
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
57.5
9.7
11
*
N05BA09
ATC
clobazam; oral
31.5
9.5
12
*
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
104.2
9.5
10
*
2151
FHL
Resection, big brain
104.2
9.5
10
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.4
8.6
34
113
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
93.4
8.5
9
*
AA1AD
NOMESCO Finland
CT of head and brain
2.4
8.4
84
452
XA800
NOMESCO Finland
Neuropsychological investigation
4.5
8.4
21
50
D33.05
ICD-10 Finland
Other lateral benign tumor in temporal lobe
+∞
8.4
8
*
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
15.7
7.8
12
8
H47.2
ICD-10 Finland
Optic atrophy
46.6
7.8
9
*
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
26.0
7.6
10
*
D33.02
ICD-10 Finland
Another benign medial tumor of the cerebrum
82.7
7.5
8
*
D32.06
ICD-10 Finland
Benign tumor of the meninges os petrosum or clivus area
+∞
7.3
7
*
9161/1-C71.6
ICD-O-3
Hemangioblastoma of cerebellum, NOS
+∞
7.3
7
*
H01AC01
ATC
somatropin; parenteral
+∞
7.3
7
*
N03AG01
ATC
valproic acid; systemic, rectal
3.7
7.2
24
71
78020
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Convulsions
20.8
7.2
10
5
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.0
7.2
33
120
H03AA01
ATC
levothyroxine sodium; systemic
2.3
7.0
67
351
H02AB02
ATC
dexamethasone; systemic
2.8
7.0
38
152
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
11.4
6.9
12
11
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.9
6.8
35
135
102
Kela drug reimbursment
Diabetes insipidus
41.3
6.8
8
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.4
6.6
54
263
D33.39
ICD-10 Finland
Benign tumor of the cranial nerves UNS
71.8
6.5
7
*
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
11.5
6.4
11
10
D33.08
ICD-10 Finland
Another benign tumor of the cerebral ventricle
+∞
6.3
6
*
E22.1
ICD-10 Finland
Hyperprolactinaemia
+∞
6.3
6
*
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
27.5
6.3
8
*
WF099
NOMESCO Finland
Other radiotherapy
27.5
6.3
8
*
CS494
NOMESCO Finland
Other visual field testing
8.0
6.2
13
17
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
13.0
6.1
10
8
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
51
204
2.93
9.47
3.4
1.9
316.57
383.96
nmol/l
1.35
46
192
153
1157
1.98
5.47
5.7
5.4
6.42
6.63
mmol/l
0.71
148
1091
11
14
8.19
5.41
1.5
1.4
—
—
—
0
0
129
965
1.78
4.32
8.7
7.4
1.22
1.21
mmol/l
0.20
118
838
116
876
1.66
3.49
8.0
6.5
1.21
1.21
mmol/l
0.20
111
806
39
225
1.88
2.99
9.5
9.8
1.73
0.89
mmol/l
0.98
32
191
6
10
6.13
2.71
1.0
1.5
—
—
—
0
0
110
860
1.54
2.63
3.1
2.5
79.10
77.26
nmol/l
0.26
101
767
40
245
1.77
2.53
1.8
1.8
—
—
—
0
0
7
16
4.48
2.49
1.3
1.3
2.56
1.86
mmol/l
—
7
16
42
268
1.70
2.31
6.4
7.0
103.40
104.22
mmol/l
0.36
42
268
8
23
3.57
2.29
1.1
1.2
—
—
—
0
0
49
328
1.63
2.24
1.8
1.9
—
—
—
0
0
8
24
3.42
2.20
1.1
1.2
—
—
—
0
0
65
468
1.54
2.19
2.2
2.4
—
—
—
0
0
65
469
1.54
2.17
5.8
4.3
1.02
1.02
kg/l
0.41
47
303
7
19
3.77
2.17
1.1
1.1
—
—
—
0
0
110
888
1.46
2.11
2.6
2.8
—
—
estimate
—
0
0
14
63
2.30
2.05
2.1
2.0
23.72
24.29
mmol/l
0.27
14
63
24
136
1.85
1.96
7.3
9.1
1.25
1.40
%
0.38
24
136
7
22
3.25
1.89
1.1
1.1
—
—
—
0
0
66
491
1.48
1.89
2.0
2.1
3.10
2.97
mg/l
0.15
53
439
48
335
1.55
1.84
1.8
1.7
1416.79
1229.33
nmol/l
0.57
39
258
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
12
4.23
1.83
1.4
1.3
—
—
—
0
0
8
29
2.82
1.81
1.7
1.5
0.17
0.45
nmol/l
—
8
20
23
133
1.81
1.78
7.3
6.9
24.42
24.39
mmol/l
0.01
23
133
25
151
1.74
1.68
2.6
2.5
63.73
63.37
ml/min/173m2
0.02
11
65
10
41
2.50
1.66
1.4
1.6
—
—
—
0
0
35
233
1.59
1.64
1.8
1.9
—
—
—
0
0
21
123
1.78
1.57
8.0
9.6
24.90
24.33
mmol/l
0.53
21
123
96
788
1.38
1.56
3.9
4.1
32.69
112.55
ng/l
0.57
73
564
22
133
1.72
1.49
7.9
9.4
0.66
0.65
%
0.05
22
133
5
16
3.17
1.44
1.2
1.2
—
—
—
0
0
27
176
1.61
1.39
6.0
7.8
1.29
1.29
mmol/l
0.01
27
176
5
17
2.98
1.36
3.8
3.0
3.72
3.29
nmol/l
—
5
17
22
138
1.66
1.32
4.2
3.5
75.16
74.32
ng/l
0.03
22
123
17
99
1.77
1.31
4.8
3.6
23.92
24.44
mmol/l
0.41
17
99
164
1488
1.36
1.29
6.1
4.5
14.89
14.78
pmol/l
0.18
150
1357
72
580
1.35
1.28
1.8
1.7
20.93
20.61
nmol/l
0.06
66
488
18
108
1.72
1.26
2.3
3.6
1.50
1.36
mmol/l
—
7
84
52
408
1.36
1.08
1.6
1.8
467.73
473.21
pmol/l
0.05
41
346
5
22
2.30
1.04
1.6
1.4
—
—
—
0
0
198
1874
1.43
1.03
20.5
16.0
27.37
22.23
mg/l
1.19
174
1532
74
619
1.29
0.99
3.7
2.6
56.50
54.60
u/l
0.23
68
575
72
602
1.29
0.96
5.7
4.2
0.00
0.01
estimate
0.50
16
224
11
62
1.81
0.96
1.2
1.2
—
—
—
0
0
31
228
1.42
0.95
5.4
4.8
34.20
32.52
%
0.36
25
147
6
27
2.25
0.94
1.0
1.1
6.30
7.95
mmol/l
—
6
22
17
110
1.59
0.93
1.9
1.6
—
—
—
0
0
32
239
1.39
0.90
6.7
6.1
1.06
1.04
mmol/l
0.21
32
218
10
57
1.79
0.85
4.4
3.1
3.65
3.95
mmol/l
—
10
57
70
593
1.26
0.84
3.0
3.6
1020.85
1330.23
ng/l
0.56
60
509
16
106
1.55
0.81
3.6
2.6
1.24
1.24
%
0.00
16
106
6
33
1.84
0.79
2.3
2.2
—
—
—
0
0
13
197
0.64
0.79
1.6
1.9
—
—
—
0
0
15
220
0.66
0.79
1.7
2.0
—
—
—
0
0
5
24
2.11
0.75
1.0
1.3
—
—
—
0
0
5
24
2.11
0.75
1.0
1.3
—
—
—
0
0
5
24
2.11
0.75
1.0
1.3
—
—
—
0
0
7
40
1.77
0.72
1.6
2.7
7.03
8.64
pmol/l
—
7
40
10
61
1.67
0.69
1.2
1.3
—
—
—
0
0
27
206
1.35
0.69
11.1
8.1
—
—
—
0
0
92
819
1.21
0.68
5.2
3.9
0.00
0.02
estimate
0.50
15
198
5
29
1.74
0.64
1.0
1.5
—
—
—
0
0
122
1122
1.19
0.61
9.5
10.0
4.33
4.08
e9/l
0.56
106
979
10
64
1.59
0.59
2.6
1.7
—
—
—
0
0
15
106
1.44
0.59
4.3
2.5
0.63
0.62
%
0.07
15
106
188
1803
1.24
0.58
18.8
15.5
82.94
81.48
ml/min/173m2
0.40
174
1673
115
1062
1.17
0.53
5.4
4.0
0.00
0.00
estimate
-0.00
17
236
116
1072
1.17
0.53
5.3
4.1
0.00
6.85
estimate
0.50
19
237
18
135
1.36
0.53
1.9
1.5
—
—
—
0
0
12
83
1.47
0.53
2.4
2.1
1.55
1.53
g/l
0.03
12
73
9
64
1.42
0.52
1.7
2.8
—
—
—
0
0
156
1478
1.18
0.51
8.9
8.1
79.59
78.20
u/l
0.14
147
1403
14
188
0.73
0.49
2.7
3.7
—
—
—
0
0
40
340
1.21
0.47
3.5
2.7
0.31
0.95
e6/l
3.12
18
181
8
118
0.67
0.47
1.5
2.3
—
—
—
0
0
100
921
1.15
0.46
3.1
3.0
138.39
102.40
ug/l
1.09
93
863
39
332
1.21
0.46
3.5
3.8
0.85
0.81
mmol/l
1.31
39
311
46
527
0.84
0.45
2.2
2.9
330.66
338.74
umol/l
0.17
38
464
116
1082
1.15
0.44
5.3
4.1
0.00
0.00
estimate
-0.00
19
221
8
57
1.42
0.42
1.3
1.4
—
—
—
0
0
0
17
0.00
0.41
0.0
1.4
—
—
—
0
0
7
104
0.66
0.40
1.4
2.1
—
—
—
0
0
75
819
0.87
0.40
2.1
1.9
1.61
1.39
mmol/l
0.94
65
693
5
35
1.44
0.39
1.6
1.4
—
—
—
0
0
5
35
1.44
0.39
1.6
1.4
—
—
—
0
0
44
385
1.18
0.39
2.9
4.1
25.79
247.84
ng/l
1.89
36
297
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
18
143
1.28
0.38
2.9
2.5
—
13.84
—
0
9
10
72
1.41
0.37
4.2
1.6
3.66
4.73
ug/l
—
10
65
5
77
0.64
0.36
1.4
3.1
12.00
2660.09
u/ml
—
5
66
6
41
1.48
0.36
1.2
1.3
—
—
—
0
0
36
312
1.18
0.36
3.4
2.9
2.13
3.27
e6/l
0.39
13
153
6
44
1.37
0.34
1.2
2.0
—
—
—
0
0
201
1965
1.19
0.33
13.8
12.1
25.49
25.90
u/l
0.13
192
1920
6
46
1.31
0.33
3.7
1.7
135.50
216.83
pmol/l
—
6
41
92
861
1.11
0.31
2.4
2.1
103.24
99.66
pmol/l
0.28
58
444
7
57
1.24
0.29
1.0
1.1
—
6.43
—
0
10
36
404
0.87
0.28
1.4
1.4
69.54
28.66
iu/ml
0.32
11
134
8
62
1.30
0.28
1.4
1.3
—
—
—
0
0
8
63
1.28
0.28
3.0
1.7
28.50
39.57
nmol/l
—
8
58
8
66
1.22
0.27
1.7
1.9
—
—
—
0
0
9
74
1.22
0.25
1.7
1.9
—
—
—
0
0
5
40
1.26
0.22
1.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
24.05
—
0
12
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
119.04
—
0
13
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
6
48
1.26
0.20
1.5
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
190.69
—
0
14
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
44
406
1.10
0.19
4.4
4.3
22.27
21.50
%
0.14
22
191
34
372
0.90
0.19
1.4
1.4
14.11
9.63
u/ml
0.18
14
155
15
128
1.18
0.18
2.5
3.6
257.27
223.24
ng/l
0.07
15
117
7
59
1.19
0.18
1.7
1.6
—
0.10
—
0
8
181
1842
0.92
0.17
5.5
5.1
1.49
1.48
mmol/l
0.08
171
1718
5
67
0.74
0.17
2.0
1.4
—
8.89
—
0
14
8
72
1.12
0.16
1.8
1.8
—
—
—
0
0
6
79
0.75
0.16
2.2
2.2
4.36
3.52
mg/l
—
6
63
61
578
1.08
0.15
4.1
2.9
0.32
0.32
e6/l
0.00
47
415
205
2026
1.12
0.15
30.5
24.2
4.42
4.47
e12/l
0.71
200
1975
174
1769
0.93
0.14
4.7
4.3
1.30
1.26
mmol/l
0.36
165
1637
21
231
0.90
0.13
2.9
3.3
4.87
7.29
umol/l
0.72
16
209
58
608
0.94
0.13
3.7
3.4
0.00
0.00
estimate
-0.00
16
187
65
626
1.05
0.10
3.6
4.0
10.27
6.92
mg/mmol
0.26
36
396
44
462
0.94
0.10
1.8
1.8
1.24
1.29
mg/l
0.04
28
366
5
47
1.07
0.09
1.0
1.7
—
—
—
0
0
13
116
1.13
0.09
1.0
1.0
—
—
—
0
0
183
1850
0.95
0.09
5.4
5.2
4.67
4.62
mmol/l
0.24
172
1736
6
55
1.09
0.09
1.0
1.7
—
—
—
0
0
6
58
1.04
0.08
1.0
1.7
—
—
—
0
0
7
64
1.10
0.08
1.7
1.5
—
—
—
0
0
9
101
0.89
0.06
1.2
1.3
—
—
—
0
0
177
1755
1.04
0.05
6.4
6.4
39.07
39.32
mmol/mol
0.15
166
1662
11
100
1.11
0.05
1.1
1.3
—
—
—
0
0
50
513
0.97
0.04
1.3
1.3
1.14
1.65
u/ml
0.34
19
138
15
160
0.93
0.04
2.1
1.4
—
—
—
0
0
131
1324
0.98
0.04
5.4
3.4
56.20
45.35
u/l
0.88
123
1250
177
1760
1.03
0.02
6.7
5.5
1.59
1.89
mu/l
3.68
165
1623
39
381
1.03
0.02
1.2
1.6
—
—
—
0
0
33
322
1.03
0.02
1.8
1.5
—
—
—
0
0
187
1878
0.98
0.01
5.9
5.9
2.77
2.69
mmol/l
0.71
174
1757
20
194
1.03
0.00
1.6
4.4
2.24
31.68
ug/l
0.76
14
162
180
1806
0.98
0.00
5.4
5.1
5.74
5.93
mmol/l
1.62
170
1669
32
321
1.00
0.00
3.3
2.9
0.76
0.78
ug/l
0.05
25
194
69
686
1.01
0.00
3.3
3.2
2.35
2.36
mmol/l
0.42
63
628
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
120
1200
1.00
-0.00
2.7
3.2
—
—
—
0
0
5
58
0.86
-0.00
1.2
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
6
0.00
-0.00
0.0
1.0
—
141.33
—
0
6
5
49
1.02
-0.00
1.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
4.3
—
98.44
—
0
9
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
7
0.00
-0.00
0.0
2.6
—
97.57
—
0
7
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
1654.88
—
0
8
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
52.23
—
0
8
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
5
57
0.87
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.28
—
0
5
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_BRAIN_NOS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BRAIN_NOS | 1.973 [1.46, 2.67] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.021 |
During the follow-up period (1.1.1998 — 31.12.2019), 87 out of 375 females with CD2_BENIGN_BRAIN_NOS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_BRAIN_NOS | 1.925 [1.33, 2.79] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.015 |
During the follow-up period (1.1.1998 — 31.12.2019), 59 out of 249 males with CD2_BENIGN_BRAIN_NOS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_BRAIN_NOS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.144% | 0.407% |
| 5 | 1.001% | 2.468% |
| 10 | 2.701% | 5.618% |
| 15 | 4.635% | 10.786% |
| 20 | 7.798% | 17.817% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_BRAIN_NOS – Benign neoplasm: Brain, unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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