No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1369 |
4. Check minimum number of eventsNone |
1369 |
5. Include endpointsNone |
1369 |
6. Filter based on genotype QC (FinnGen only) |
1210 |
Control definitions (FinnGen only)
- Control exclude
- E4_THYROID
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E04
- Name in latin
- Struma atoxica diffusa
Similar endpoints
↥List of similar endpoints to
Nontoxic diffuse goitre
based on the number of shared cases.
Similar with more cases:
- Nontoxic goitre/thyroid nodule
- Benign thyroid growths and nodules
- Disorders of the thyroid gland
- Used for control exclusion in common control thyroid runs
- Endocrine, nutritional and metabolic diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8966 | 7514 | 1404 |
| Only index persons | 7805 | 6684 | 1121 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.19 | 0.22 | 0.04 |
| Only index persons | 0.22 | 0.25 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 54.97 | 54.35 | 58.33 |
| Only index persons | 53.79 | 53.13 | 57.68 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1210 | 1025 | 185 |
| Unadjusted period prevalence (%) | 0.32 | 0.36 | 0.08 |
| Median age at first event (years) | 53.26 | 52.21 | 59.09 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1256
- Matched controls
- 12560
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E04.1
ICD-10 Finland
Nontoxic single thyroid nodule
120.3
310.8
158
15
E04.0
ICD-10 Finland
Nontoxic diffuse goitre
8818.9
307.7
1070
*
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
471.5
307.7
343
10
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
126.1
307.7
306
32
H03AA01
ATC
levothyroxine sodium; systemic
108.8
307.7
703
145
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
433.7
307.7
465
17
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
161.8
307.7
297
24
104
Kela drug reimbursment
Thyroid insufficiency
627.7
306.9
292
6
BAA60
NOMESCO Finland
Total thyroidectomy
2610.4
243.8
228
*
E03.89
ICD-10 Finland
Other specified hypothyroidism
131.4
236.0
119
10
H03BB01
ATC
carbimazole; oral
94.7
229.7
120
14
T86
ICPC
Hypothyroidism/myxoedema
80.8
181.7
97
13
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
+∞
161.0
151
*
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
37.7
146.0
91
26
24099
ICD-8 Finland
Simple goitre, Unspecified
+∞
127.3
120
*
E03
ICD-10 Finland
Other hypothyroidism
233.1
124.2
126
6
EP1AE
NOMESCO Finland
Neck ultrasound examination
6.8
101.4
171
283
E05.0
ICD-10 Finland
Thyrotoxicosis with diffuse goitre
+∞
84.3
80
*
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
13.8
82.5
78
60
D44.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thyroid gland
32.5
81.7
53
17
E05.2
ICD-10 Finland
Thyrotoxicosis with toxic multinodular goitre
795.3
77.2
75
*
E05.9
ICD-10 Finland
Thyrotoxicosis, unspecified
207.7
76.1
78
*
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
15.5
73.8
65
44
BA1AE, ,
SPAT
13.5
60.9
58
45
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
58.8
56
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
51.4
49
*
24199
ICD-8 Finland
Non-toxic nodular goitre, Unspecified
+∞
51.4
49
*
E04.8
ICD-10 Finland
Other specified nontoxic goitre
265.8
50.5
51
*
2504
FHL
Unilateral resection or enucleation
431.6
42.4
42
*
D34
ICD-10 Finland
Benign neoplasm of thyroid gland
148.3
41.0
43
*
E04
ICD-10 Finland
Other nontoxic goitre
76.1
39.2
44
6
BAA20
NOMESCO Finland
Unilateral partial excision of thyroid gland
179.9
33.9
35
*
2400A
ICD-9 Finland
Simple and unspecified goitre, Goitre, specified as simple
+∞
32.4
31
*
BAA25
NOMESCO Finland
Bilateral partial excision of thyroid gland
+∞
28.2
27
*
XX7CT
NOMESCO Finland
Radioiodine therapy of thydoid tissue
+∞
27.2
26
*
E05.80
ICD-10 Finland
Subacute thyrotoxicosis
63.5
27.0
31
5
24010
ICD-8 Finland
Simple goitre, Sporadic
+∞
26.1
25
*
BAA50
NOMESCO Finland
Lobectomy and resection of contralateral lobe of thyroid gland
+∞
25.1
24
*
2505
FHL
Bilateral resection (also used if total removal has been performed on the other side)
92.0
24.7
27
*
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
3.7
23.4
77
219
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.1
22.0
94
316
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
223.7
21.7
22
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
21.4
543
3759
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
106.7
19.6
21
*
EP1AE, ,
SPAT
4.4
19.4
49
115
E03.0
ICD-10 Finland
Congenital hypothyroidism with diffuse goitre
+∞
18.8
18
*
C73.92
ICD-10 Finland
Follicular carcinoma of the thyroid gland
+∞
18.8
18
*
E06.1
ICD-10 Finland
Subacute thyroiditis
+∞
17.7
17
*
T81
ICPC
Goitre
18.9
17.4
26
14
R06.0
ICD-10 Finland
Dyspnoea
1.8
17.1
371
2422
2411A
ICD-9 Finland
Non-toxic nodular goitre, Non-toxic multinodular goitre
+∞
16.7
16
*
R13
ICD-10 Finland
Dysphagia
2.5
16.4
111
475
E06.3
ICD-10 Finland
Autoimmune thyroiditis
40.7
16.4
20
5
A11CC03
ATC
alfacalcidol; systemic
4.5
16.2
39
88
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
6.5
15.9
26
41
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
22.4
15.6
22
10
N02BE01
ATC
paracetamol; systemic, rectal
2.3
15.5
1151
10374
E89.00
ICD-10 Finland
Postirradiation hypothyroidism
+∞
14.6
14
*
106
Kela drug reimbursment
Hypoparathyroidism
81.1
14.6
16
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
5.6
14.3
27
49
GB1AA
NOMESCO Finland
Tracheal X-ray examination
+∞
13.6
13
*
N02AX02
ATC
tramadol; systemic, rectal
1.6
13.4
536
4030
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
12.7
314
2099
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
12.6
498
3724
2419X
ICD-9 Finland
Non-toxic nodular goitre, Unspecified non-toxic nodular goitre
+∞
12.5
12
*
C73.90
ICD-10 Finland
Malignant tumor of the thyroid gland (thyroid gland) without histology
+∞
12.5
12
*
R42
ICD-10 Finland
Dizziness and giddiness
1.6
12.2
319
2157
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
12.2
295
1958
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
12.1
241
1516
XA402
NOMESCO Finland
ENMG
3.3
12.0
44
135
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
11.6
456
3390
JN5PN
NOMESCO Finland
Isotope imaging of secondary neoplasms of thyroid origin
+∞
11.5
11
*
A11CC02
ATC
dihydrotachysterol; oral
121.1
11.4
12
*
A02BC05
ATC
esomeprazole; systemic
1.5
11.2
514
3938
E05
ICD-10 Finland
Thyrotoxicosis [hyperthyroidism]
25.3
11.1
15
6
A02BC02
ATC
pantoprazole; systemic
1.5
11.0
868
7433
M01AE02
ATC
naproxen; oral, rectal
1.5
10.6
697
5727
R01AD09
ATC
mometasone; nasal
1.5
10.6
556
4367
M79.6
ICD-10 Finland
Pain in limb
1.5
10.5
574
4543
E05.1
ICD-10 Finland
Thyrotoxicosis with toxic single thyroid nodule
+∞
10.4
10
*
H06.2*E05.9
ICD-10 Finland
Dysthyroid exophthalmos
+∞
10.4
10
*
G44.2
ICD-10 Finland
Tension-type headache
1.7
10.0
190
1178
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
9.8
368
2686
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
9.7
357
2594
N03AX16
ATC
[U] pregabalin
1.6
9.6
292
2034
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
9.6
349
2529
J01FA09
ATC
clarithromycin; systemic
1.5
9.5
377
2780
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.7
9.4
166
1006
C07AB07
ATC
bisoprolol; oral
1.5
9.4
589
4752
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
+∞
9.4
9
*
8330/3-C73.9
ICD-O-3
Follicular carcinoma, NOS, of thyroid gland
+∞
9.4
9
*
WZC30
NOMESCO Finland
Teaching
1.7
9.4
207
1334
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
9.4
357
2612
ZYC01, ,
SPAT
1.9
9.3
130
734
L03
ICPC
Low back symptom/complaint
1.5
9.3
378
2802
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
2.8
9.2
47
175
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
9.2
241
1619
R51.80
ICD-10 Finland
Headache
1.7
9.0
201
1297
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
9.0
377
2810
E07.9
ICD-10 Finland
Disorder of thyroid, unspecified
18.7
8.9
13
7
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
8.9
174
1085
R03AC02
ATC
salbutamol; inhalant
1.4
8.9
672
5592
UJF32
NOMESCO Finland
Coloscopy
1.5
8.6
319
2312
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.8
8.6
134
782
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
8.6
231
1562
E89.09
ICD-10 Finland
Postprocedural hypothyroidism, other or several procedures
90.7
8.4
9
*
Z50.5
ICD-10 Finland
Speech therapy
4.3
8.4
21
49
R53
ICD-10 Finland
Malaise and fatigue
1.5
8.4
312
2262
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
8.4
295
2116
R00.2
ICD-10 Finland
Palpitations
1.9
8.4
113
632
19399
ICD-8 Finland
Malignant neoplasm of thyroid gland
+∞
8.3
8
*
2410A
ICD-9 Finland
Non-toxic nodular goitre, Non-toxic uninodular goitre
+∞
8.3
8
*
24000
ICD-8 Finland
Simple goitre, Endemic
+∞
8.3
8
*
J01AA02
ATC
doxycycline; systemic
1.5
8.3
966
8653
E83.51
ICD-10 Finland
Hypocalcemia
8.6
8.3
17
20
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
3.9
8.3
24
63
K08.80
ICD-10 Finland
Toothache NOS
1.8
8.3
115
649
T72
ICPC
Benign neoplasm thyroid
14.6
8.2
13
9
C07AA05
ATC
propranolol; systemic
1.6
8.1
239
1646
XG466
NOMESCO Finland
Sleep oxymetry
2.9
8.1
37
130
J01FA06
ATC
roxithromycin; oral
1.4
8.1
485
3850
J01DA01
ATC
[U] cefalexin
1.4
8.0
739
6317
Z01.2
ICD-10 Finland
Dental examination
1.4
8.0
546
4430
ZYC05, ,
SPAT
2.8
8.0
40
148
M01AH05
ATC
etoricoxib; oral
1.4
8.0
757
6504
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
7.9
535
4331
M03BX02
ATC
tizanidine; oral
1.4
7.8
752
6462
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
7.8
845
7416
A29
ICPC
General symptom/complaint other
1.6
7.7
171
1102
M54.5
ICD-10 Finland
Low back pain
1.4
7.6
446
3518
BBA70
NOMESCO Finland
Implantation or transplantation of parathyroid gland
25.2
7.6
10
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
7.6
417
3252
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.2
7.6
63
296
G47.3
ICD-10 Finland
Sleep apnoea
1.5
7.5
225
1554
J01DB01
ATC
cefalexin; oral
1.5
7.5
992
8992
M79.7
ICD-10 Finland
Fibromyalgia
2.4
7.5
52
226
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.7
7.5
158
1005
A12AA04
ATC
calcium carbonate; oral
3.9
7.4
21
54
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
7.4
558
4590
J01MA02
ATC
ciprofloxacin; systemic
1.4
7.4
440
3477
K10.3
ICD-10 Finland
Alveolitis of jaws
2.2
7.4
61
286
M70.6
ICD-10 Finland
Trochanteric bursitis
1.6
7.4
203
1377
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.8
7.3
110
636
E89.0
ICD-10 Finland
Postprocedural hypothyroidism
+∞
7.3
7
*
24599
ICD-8 Finland
Thyroiditis, Unspecified
+∞
7.3
7
*
E06
ICD-10 Finland
Thyroiditis
+∞
7.3
7
*
C73
ICD-10 Finland
Malignant neoplasm of thyroid gland
+∞
7.3
7
*
TBA20
NOMESCO Finland
Aspiration cytology of thyroid gland
+∞
7.3
7
*
T71
ICPC
Malignant neoplasm thyroid
+∞
7.3
7
*
BAA99
NOMESCO Finland
Other operation on thyroid gland
+∞
7.3
7
*
R52.9
ICD-10 Finland
Pain, unspecified
1.7
7.3
125
751
E06.9
ICD-10 Finland
Thyroiditis, unspecified
30.2
7.2
9
*
B01AB05
ATC
enoxaparin; parenteral
1.4
7.1
388
3014
R49.01
ICD-10 Finland
Functional dysphonia
2.4
7.1
45
188
M01AX17
ATC
nimesulide; oral
1.5
7.1
304
2261
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
3.1
7.0
28
91
XG410
NOMESCO Finland
Flow-volume spirometry
2.3
7.0
49
214
ZYC05
NOMESCO Finland
Non-real-time text-based remote communication
3.3
7.0
25
76
R49.03
ICD-10 Finland
Atrophic dysphonia
4.0
6.9
19
48
ZXA05
NOMESCO Finland
Left side
1.5
6.9
292
2164
R51
ICD-10 Finland
Headache
2.0
6.9
68
342
CJB10
NOMESCO Finland
Laser discission of secondary cataract
1.7
6.8
118
713
DQE10
NOMESCO Finland
Injection of foreign material into vocal cord
16.8
6.7
10
6
C08CA02
ATC
felodipine; oral
1.7
6.7
114
684
ZXA00
NOMESCO Finland
Right side
1.4
6.7
316
2390
S04
ICPC
Lump/swelling localized
1.7
6.6
136
858
R21
ICPC
Throat symptom/complaint
1.5
6.6
229
1629
L15
ICPC
Knee symptom/complaint
1.4
6.6
329
2509
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
6.6
234
1673
R02
ICPC
Shortness of breath/dyspnoea
1.6
6.6
164
1085
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
6.6
631
5358
R60.0
ICD-10 Finland
Localized oedema
1.6
6.4
160
1059
J01FA10
ATC
azithromycin; systemic
1.4
6.4
669
5743
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
6.4
743
6482
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
6.3
551
4602
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
6.3
247
1802
T85
ICPC
Hyperthyroidism/thyrotoxicosis
18.1
6.3
9
5
L01
ICPC
Neck symptom/complaint
1.5
6.3
210
1484
8341/3-C73.9
ICD-O-3
Papillary microcarcinoma of thyroid gland
+∞
6.3
6
*
E07.89
ICD-10 Finland
Other specified disorders of thyroid
+∞
6.3
6
*
24110
ICD-8 Finland
Non-toxic nodular goitre, Sporadic
+∞
6.3
6
*
L13
ICPC
Hip symptom/complaint
1.4
6.1
265
1967
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.9
6.1
71
379
J38.3
ICD-10 Finland
Other diseases of vocal cords
3.6
6.0
19
53
R94.6
ICD-10 Finland
Abnormal results of thyroid function studies
10.1
6.0
11
11
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
272
342
9.88
209.91
4.4
1.7
4.67
4.40
pmol/l
3.87
238
297
132
119
12.28
127.41
1.8
1.2
2.60
1.58
iu/l
1.85
43
29
67
30
23.54
92.17
5.7
1.1
365.76
56.70
u/ml
—
21
6
197
540
4.14
64.49
1.3
1.2
116.45
69.91
u/ml
0.81
75
175
1127
8509
4.16
57.86
9.2
2.8
15.64
14.49
pmol/l
41.27
1078
7728
56
7
83.76
50.34
6.4
1.1
10.82
52.50
ug/l
—
36
7
852
5869
2.40
45.29
6.9
6.5
1.21
1.22
mmol/l
1.50
754
5071
235
908
2.95
43.99
3.2
3.5
63.63
85.51
ng/l
5.93
201
775
107
244
4.70
43.98
1.3
1.2
—
—
—
0
0
774
5225
2.25
41.52
6.9
5.8
1.21
1.22
mmol/l
1.26
725
4813
1158
10155
2.80
22.45
10.9
4.1
1.56
1.92
mu/l
15.10
1105
9342
978
8374
1.76
15.11
5.2
4.5
12.19
13.03
mm/h
1.09
922
7814
682
5446
1.55
12.90
2.8
2.5
79.76
79.57
nmol/l
0.06
612
4920
787
6503
1.56
12.66
5.2
4.6
6.67
6.60
mmol/l
0.46
756
6158
546
4212
1.52
11.70
4.3
3.8
142.75
147.20
ng/l
0.01
383
2963
548
4262
1.51
11.12
3.5
3.5
2.35
2.37
mmol/l
2.88
494
3872
325
2283
1.57
10.42
1.4
1.3
32.71
34.78
iu/ml
0.11
83
708
456
3457
1.50
10.25
3.3
3.0
1023.04
1256.25
ng/l
0.87
406
2976
280
1932
1.58
9.60
2.9
2.9
1.01
1.31
e6/l
0.93
176
985
166
1006
1.75
9.42
2.6
1.9
354.56
384.59
nmol/l
1.31
154
925
646
5306
1.45
9.36
2.7
2.7
—
—
estimate
—
0
0
975
8696
1.54
9.13
8.8
8.0
77.78
79.14
u/l
0.47
923
8227
295
2096
1.53
8.80
1.4
1.3
10.09
11.57
u/ml
0.15
117
790
377
2819
1.48
8.79
2.4
2.3
—
—
—
0
0
217
1453
1.60
8.37
1.9
2.3
103.86
103.00
ug/g
0.02
168
1141
455
3589
1.42
7.79
2.8
2.5
60.25
85.27
u/l
0.57
420
3317
1121
10431
1.69
7.72
18.2
15.6
79.49
79.06
ml/min/173m2
0.31
1058
9659
614
5134
1.38
7.32
15.0
14.0
1.25
1.23
inr
0.34
493
4197
709
6079
1.38
7.20
6.1
6.3
10.31
11.05
umol/l
1.93
681
5788
33
120
2.80
6.84
1.8
1.3
25.09
22.92
ng/l
0.28
33
120
345
2654
1.41
6.60
1.4
1.3
0.77
1.56
u/ml
2.27
92
681
204
1421
1.52
6.52
4.5
4.9
1.02
1.05
mmol/l
0.81
184
1301
186
1273
1.54
6.45
2.4
2.5
6.06
7.50
umol/l
0.81
160
1112
370
2896
1.39
6.37
4.0
3.8
93.12
92.23
%
0.27
357
2835
449
3632
1.37
6.30
3.5
3.2
35.66
65.05
e6/l
0.74
366
2728
329
2532
1.41
6.23
2.0
1.6
1.21
1.12
mg/l
0.20
253
1970
123
776
1.65
6.00
2.5
2.4
14.89
18.12
au/ml
0.21
14
67
441
3595
1.35
5.78
2.2
2.1
145.26
198.91
u/l
1.27
425
3403
46
219
2.14
5.41
1.8
1.9
4.69
4.94
mmol/24h
0.20
38
191
14
26
5.43
5.23
1.0
1.2
—
—
—
0
0
385
3119
1.34
5.14
3.4
3.1
0.28
0.42
e6/l
0.96
299
2233
63
344
1.88
5.09
1.3
1.3
1.64
8.13
u/ml
—
7
69
343
2738
1.35
5.04
2.6
2.5
319.07
326.92
umol/l
0.72
304
2401
318
2510
1.36
5.03
3.3
2.9
2.44
2.46
mmol/l
2.05
287
2278
1162
11095
1.63
5.00
21.4
18.3
139.97
139.67
mmol/l
4.28
1143
10871
1163
11111
1.63
4.94
21.5
18.5
3.94
3.96
mmol/l
2.00
1144
10856
246
1872
1.39
4.87
2.8
3.0
0.82
0.82
mmol/l
0.05
229
1765
233
1761
1.40
4.79
3.1
3.0
3.75
3.41
e6/l
0.12
131
812
62
344
1.84
4.79
1.3
1.3
1.11
3.17
u/ml
—
7
44
1132
10765
1.52
4.72
19.0
15.6
19.78
23.64
mg/l
4.53
967
8822
288
2265
1.35
4.62
1.5
1.5
2.26
2.36
g/l
0.46
171
1326
53
283
1.91
4.61
1.2
1.3
1.16
5.00
u/ml
—
5
24
600
5223
1.28
4.58
4.5
4.6
35.98
35.54
g/l
1.28
565
4901
680
6023
1.28
4.48
4.8
4.1
0.00
0.00
estimate
0.80
134
1243
243
1869
1.37
4.48
1.6
1.5
—
—
—
0
0
443
3718
1.30
4.47
3.9
3.9
4.87
8.78
mg/mmol
2.34
251
2187
686
6086
1.28
4.45
4.8
4.1
9.33
5.01
estimate
0.18
144
1282
60
338
1.81
4.43
1.5
1.4
268.52
302.71
ug/g
0.69
33
191
365
2999
1.31
4.28
2.4
2.3
3.08
2.89
mg/l
0.86
314
2588
38
185
2.09
4.28
1.3
1.2
15.54
14.19
u/l
0.23
29
151
14
41
3.44
4.19
1.3
2.7
20.32
212.73
ug/l
0.48
14
36
133
929
1.48
4.19
2.3
2.3
0.42
0.56
e6/l
0.40
123
878
14
35
4.03
4.10
1.0
1.3
—
—
—
0
0
80
504
1.63
3.99
2.0
2.0
3.27
7.93
iu/ml
1.60
15
123
310
2515
1.31
3.96
2.6
2.6
5.10
6.82
e6/l
1.98
286
2275
188
1416
1.39
3.93
5.1
5.0
33.51
33.28
%
0.09
124
887
719
6471
1.26
3.91
9.9
9.5
3.90
4.08
e9/l
1.45
625
5595
687
6153
1.26
3.89
4.8
4.1
0.06
0.26
estimate
0.37
135
1213
445
3789
1.27
3.88
3.3
3.2
6.90
6.77
mmol/l
0.26
370
3199
596
5254
1.26
3.86
3.4
3.0
109.19
109.37
ug/l
0.01
537
4919
592
5217
1.25
3.84
2.2
2.1
96.83
96.80
pmol/l
0.00
289
2541
825
7555
1.27
3.83
5.7
5.0
1821.67
2990.38
e6/l
—
9
104
1104
10527
1.40
3.74
6.0
5.1
6.00
5.88
mmol/l
1.60
1022
9627
48
269
1.82
3.65
1.2
1.3
5.50
42.06
u/ml
—
8
38
166
1246
1.38
3.54
5.2
4.3
244.71
254.52
u/l
0.25
156
1169
323
2680
1.28
3.42
5.1
4.2
1.02
1.58
kg/l
0.50
212
1784
1077
10258
1.35
3.41
7.2
6.2
39.96
39.07
mmol/mol
2.71
1013
9579
88
593
1.52
3.33
1.5
1.5
—
—
—
0
0
30
148
2.05
3.32
1.1
1.3
—
—
—
0
0
30
149
2.04
3.27
1.1
1.3
—
—
—
0
0
87
591
1.51
3.18
1.5
1.3
32.70
32.16
iu/l
0.05
75
522
28
138
2.05
3.12
1.0
1.3
—
—
—
0
0
1180
11445
1.51
3.09
24.5
20.6
73.86
72.77
umol/l
0.60
1166
11308
707
6447
1.22
3.05
3.1
2.9
—
—
—
0
0
28
140
2.02
3.02
1.0
1.3
—
—
—
0
0
28
140
2.02
3.02
1.0
1.3
—
—
—
0
0
1172
11362
1.47
2.97
13.8
12.1
23.32
24.10
u/l
1.56
1151
11034
29
148
1.98
2.96
1.1
1.3
—
—
—
0
0
32
170
1.91
2.92
1.3
1.2
—
0.64
nmol/l
—
0
7
509
4507
1.22
2.91
4.8
4.1
4.57
0.04
estimate
0.49
110
1025
283
2353
1.26
2.90
1.6
1.7
456.93
28976250.06
pmol/l
1.93
225
1943
54
336
1.63
2.90
3.7
3.9
24.80
24.92
mmol/l
0.10
47
301
22
102
2.18
2.88
1.1
1.1
95.36
112.06
pmol/l
1.01
22
102
28
143
1.98
2.86
1.3
1.1
0.42
0.19
nmol/l
0.47
21
110
386
3329
1.23
2.84
5.1
4.2
0.00
0.00
estimate
1.23
126
1177
57
363
1.60
2.80
1.7
1.7
—
—
—
0
0
31
166
1.89
2.78
1.3
1.2
0.53
11.52
nmol/l
0.50
31
156
17
72
2.38
2.73
1.0
1.2
—
—
—
0
0
144
1105
1.34
2.70
2.4
2.3
30.46
39.89
u/l
2.43
112
918
1059
10137
1.28
2.67
4.7
4.2
1.30
1.25
mmol/l
1.44
970
9240
35
198
1.79
2.66
1.3
1.2
—
—
—
0
0
32
176
1.84
2.65
1.1
1.1
—
2.43
—
0
7
1126
10876
1.34
2.59
6.4
5.8
2.73
2.74
mmol/l
0.13
1047
10062
5
7
7.17
2.55
1.0
1.0
4.06
6.46
nmol/l
—
5
7
54
354
1.55
2.38
1.2
1.2
—
—
—
0
0
47
299
1.59
2.36
1.7
1.9
99.74
6606.13
u/l
2.42
14
114
14
59
2.39
2.29
1.3
1.2
—
—
—
0
0
96
714
1.37
2.23
7.5
8.3
0.67
0.65
%
0.24
96
709
768
7171
1.18
2.21
3.1
3.2
42.94
46.48
u/l
0.47
725
6692
28
158
1.79
2.18
1.3
1.5
0.36
0.40
nmol/l
0.21
16
122
15
67
2.25
2.18
1.2
1.1
9.10
14.25
u/l
—
10
53
45
291
1.57
2.13
2.0
1.5
351.95
288.85
mu/l
0.47
39
267
15
68
2.22
2.11
1.2
1.1
51.80
75.18
u/l
—
10
56
26
146
1.80
2.07
1.4
1.3
26.38
30.93
u/l
0.30
21
119
1104
10694
1.27
2.02
5.6
5.1
4.69
4.75
mmol/l
1.33
1029
9929
117
912
1.31
2.01
3.7
3.7
1.22
1.23
mmol/l
1.51
105
794
65
465
1.42
1.92
1.6
2.1
41.02
40.38
u/l
0.11
54
418
15
71
2.13
1.92
1.0
1.2
—
—
—
0
0
25
143
1.76
1.90
2.1
2.4
9.09
27.92
mg/l
4.29
11
48
43
284
1.53
1.89
1.7
2.2
13.57
12.30
mg/l
0.53
37
263
96
735
1.33
1.89
7.7
8.1
1.24
1.28
%
0.22
96
728
0
52
0.00
1.88
0.0
3.6
—
43.20
—
0
5
8
28
2.87
1.86
3.0
1.6
8.41
97.69
u/l
—
8
28
33
510
0.64
1.80
3.9
4.3
1.58
1.51
%
0.19
33
479
1096
10636
1.24
1.78
5.5
5.0
1.51
1.56
mmol/l
3.82
1018
9819
106
832
1.30
1.76
1.3
1.6
—
—
—
0
0
18
95
1.91
1.76
1.8
2.3
5.50
2.32
u/field
—
10
50
1190
11672
1.37
1.74
29.0
23.9
90.75
91.30
fl
4.66
1181
11544
1190
11673
1.37
1.73
29.5
24.3
40.29
39.61
%
5.71
1181
11540
1190
11673
1.37
1.73
29.2
23.9
257.93
257.14
e9/l
0.16
1175
11432
1190
11673
1.37
1.73
29.2
24.0
6.60
6.69
e9/l
0.55
1170
11379
1190
11674
1.37
1.72
29.1
23.9
4.48
4.40
e12/l
9.13
1170
11382
17
89
1.92
1.70
1.3
1.2
—
—
—
0
0
1190
11676
1.37
1.70
29.4
24.1
133.85
132.21
g/l
4.40
1181
11550
182
1534
1.22
1.65
6.3
6.1
104.37
104.03
mmol/l
0.42
182
1534
20
112
1.80
1.65
1.2
1.1
—
46.86
—
0
7
159
1324
1.23
1.63
3.4
4.1
14.42
21.31
ug/l
0.32
129
1067
155
1288
1.23
1.62
7.3
6.5
—
—
—
0
0
5
14
3.58
1.61
2.8
2.6
0.60
1.14
u/field
—
5
14
17
91
1.88
1.61
1.3
1.2
—
—
—
0
0
17
91
1.88
1.61
1.3
1.2
—
—
—
0
0
109
872
1.27
1.58
2.4
2.3
4.80
6.33
ug/l
0.60
92
749
16
85
1.89
1.55
2.4
1.6
97.43
99.83
ng/l
0.04
16
85
131
1075
1.24
1.54
3.8
3.3
2.33
2.06
mmol/l
0.40
122
938
217
1876
1.19
1.52
2.8
2.4
12.92
12.65
umol/l
0.24
202
1745
58
429
1.37
1.47
3.1
2.3
0.38
0.94
g/l
0.86
52
367
108
873
1.26
1.46
1.6
1.5
—
—
—
0
0
92
731
1.28
1.43
8.1
8.3
94.55
94.06
%
0.51
92
725
60
449
1.35
1.42
1.4
1.3
0.27
1.43
u/ml
0.95
11
27
72
555
1.32
1.41
3.5
3.4
1.73
2.02
mmol/l
0.25
55
414
9
40
2.26
1.40
1.3
1.1
—
—
—
0
0
9
40
2.26
1.40
1.3
1.1
—
—
—
0
0
118
969
1.24
1.40
2.6
2.8
66.82
66.80
g/l
0.01
107
881
17
97
1.76
1.35
1.3
1.2
—
—
—
0
0
106
864
1.25
1.35
3.2
2.4
63.02
66.95
ml/min/173m2
0.57
51
352
44
316
1.41
1.34
2.7
3.4
5.35
2.25
index
0.36
26
151
33
224
1.49
1.34
1.6
1.3
—
—
—
0
0
0
38
0.00
1.34
0.0
1.9
—
2.19
—
0
21
17
99
1.73
1.27
1.8
1.3
—
—
—
0
0
21
131
1.61
1.24
1.2
1.1
—
41.08
—
0
13
219
1930
1.16
1.23
2.0
1.9
—
—
—
0
0
18
108
1.68
1.22
1.3
1.2
—
—
—
0
0
104
857
1.23
1.22
1.9
2.0
—
—
—
0
0
216
1907
1.16
1.19
1.8
1.7
1191.00
1182.12
nmol/l
0.04
163
1406
21
133
1.59
1.17
1.1
1.2
—
—
—
0
0
382
3510
1.13
1.16
1.7
1.7
20.10
21.25
nmol/l
0.80
316
2902
8
39
2.06
1.15
1.6
1.5
—
—
—
0
0
8
39
2.06
1.15
1.6
1.5
—
—
—
0
0
8
39
2.06
1.15
1.7
1.5
—
—
—
0
0
95
781
1.23
1.15
1.8
1.9
—
—
—
0
0
15
88
1.71
1.11
1.3
1.2
—
—
—
0
0
10
51
1.97
1.11
1.2
1.1
—
—
—
0
0
5
21
2.39
1.09
1.0
1.2
—
—
—
0
0
34
246
1.39
1.04
1.5
1.5
226.11
1715.15
e6/l
0.74
28
192
93
773
1.22
1.03
3.6
3.3
1.10
0.79
ug/l
0.52
68
496
60
478
1.27
0.98
2.9
3.1
2367.26
1064.16
u/ml
0.24
46
410
9
50
1.81
0.96
1.6
1.4
—
—
—
0
0
9
50
1.81
0.96
1.6
1.4
—
—
—
0
0
9
50
1.81
0.96
1.6
1.4
—
—
—
0
0
9
50
1.81
0.96
1.6
1.4
—
—
—
0
0
26
183
1.43
0.94
1.3
1.5
—
—
—
0
0
42
321
1.32
0.94
1.1
1.2
—
—
—
0
0
16
101
1.59
0.93
1.3
1.9
5.19
5.73
umol/l
—
7
72
6
27
2.23
0.93
1.3
1.1
112.18
152.27
pmol/l
—
6
27
196
1752
1.14
0.93
2.9
2.4
2.32
2.33
g/l
0.09
181
1621
6
28
2.15
0.91
3.3
2.3
0.64
0.62
mmol/l
—
6
28
33
244
1.36
0.91
1.5
1.4
6.54
36.57
e6/l
0.63
26
178
40
305
1.32
0.91
1.5
1.3
—
—
—
0
0
180
1603
1.14
0.91
3.0
2.4
22.64
21.92
%
0.29
166
1494
166
1472
1.15
0.89
1.9
1.8
—
—
—
0
0
35
263
1.34
0.88
2.1
1.5
—
—
—
0
0
21
144
1.47
0.87
1.0
1.0
2.45
1.85
eliau/ml
0.19
11
63
11
64
1.73
0.86
2.4
3.4
0.64
0.83
index
0.37
11
64
19
128
1.49
0.86
2.6
3.9
—
—
—
0
0
148
1306
1.15
0.86
6.5
5.7
3.05
2.66
ug/l
0.26
132
1158
6
31
1.94
0.84
1.0
1.0
—
—
—
0
0
41
319
1.29
0.83
1.1
1.2
—
—
—
0
0
6
32
1.88
0.82
4.2
1.6
111.33
73.53
nmol/24h
—
6
32
53
429
1.25
0.79
3.2
2.3
9.25
10.09
g/l
1.16
47
380
48
386
1.25
0.76
1.6
1.9
—
—
—
0
0
0
28
0.00
0.76
0.0
1.2
—
—
—
0
0
74
625
1.20
0.75
4.2
3.4
24.68
24.35
mmol/l
0.49
74
615
119
1046
1.15
0.74
4.8
4.7
21.01
22.07
%
0.35
66
502
42
334
1.27
0.74
1.4
1.3
—
—
—
0
0
88
1019
0.85
0.73
2.2
2.0
3.58
3.33
ratio
1.11
73
789
5
25
2.00
0.72
1.2
1.2
—
—
—
0
0
13
84
1.55
0.72
1.5
1.3
—
—
—
0
0
13
84
1.55
0.72
1.5
1.3
—
—
—
0
0
13
84
1.55
0.72
1.5
1.3
—
—
—
0
0
11
68
1.62
0.71
1.5
1.1
9.27
10.43
u/l
0.35
11
61
154
1383
1.13
0.71
2.0
1.8
—
—
—
0
0
32
247
1.30
0.71
3.0
3.3
956.73
1544.15
u/ml
0.17
26
223
57
473
1.21
0.70
3.1
2.4
3.02
2.96
g/l
0.18
52
426
12
77
1.56
0.68
1.4
1.7
—
—
—
0
0
9
59
1.53
0.68
1.1
1.1
—
—
—
0
0
13
192
0.67
0.68
1.2
1.4
—
—
—
0
0
244
2256
1.10
0.67
4.4
3.8
251.32
351.32
ng/l
0.27
164
1748
21
153
1.38
0.67
1.3
1.2
2.11
2.24
u/ml
—
9
54
42
339
1.25
0.67
1.9
2.6
—
—
—
0
0
85
736
1.17
0.66
2.0
1.7
—
—
—
0
0
29
372
0.77
0.66
1.4
1.6
0.11
0.36
mg/l
—
9
160
38
305
1.25
0.64
1.6
1.6
8948.85
10927.21
e6/l
0.24
27
216
6
101
0.59
0.62
1.0
1.2
—
—
—
0
0
11
71
1.55
0.62
1.7
1.6
—
—
—
0
0
31
244
1.28
0.61
1.7
1.6
—
—
—
0
0
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
59
502
1.18
0.58
3.0
2.3
3.60
3.76
g/l
0.49
53
455
59
502
1.18
0.58
3.0
2.3
7.49
7.47
g/l
0.03
54
455
59
502
1.18
0.58
3.0
2.3
4.14
4.26
g/l
0.90
54
455
42
346
1.22
0.58
6.1
4.1
1.41
1.36
mmol/l
0.11
42
340
34
419
0.81
0.57
1.5
1.5
—
—
—
0
0
453
4734
0.93
0.57
2.0
1.9
1.39
1.33
mmol/l
0.97
370
4028
50
422
1.19
0.55
1.6
1.9
0.66
1.95
ug/l
1.13
45
374
14
193
0.72
0.53
1.1
1.4
1.16
1.15
ratio
—
8
118
14
193
0.72
0.53
1.1
1.4
1.22
1.23
ratio
—
8
118
14
193
0.72
0.53
1.1
1.4
1.05
0.95
ratio
—
8
118
28
223
1.26
0.52
1.3
1.3
—
—
—
0
0
28
223
1.26
0.52
1.3
1.3
—
—
—
0
0
49
416
1.19
0.51
2.0
2.0
—
—
—
0
0
9
65
1.39
0.50
1.3
1.2
—
—
—
0
0
34
279
1.22
0.50
1.7
2.2
128.45
126.31
g/l
0.17
22
216
11
156
0.70
0.50
1.2
1.5
—
—
—
0
0
7
45
1.56
0.49
1.3
1.7
37.87
40.42
g/l
—
7
45
122
1111
1.11
0.48
3.1
3.4
—
—
—
0
0
12
85
1.42
0.47
1.0
1.1
—
—
—
0
0
141
1297
1.10
0.46
6.5
6.7
12.32
12.58
kpa
0.25
136
1248
141
1297
1.10
0.46
6.5
6.7
5.10
5.12
kpa
0.13
136
1248
20
156
1.29
0.45
1.4
1.2
1.30
1.87
u/ml
—
10
48
33
276
1.20
0.42
1.3
1.4
—
—
—
0
0
24
194
1.24
0.42
1.1
1.1
0.14
1.73
u/ml
3.16
14
106
246
2328
1.07
0.42
1.4
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
6.6
—
9.89
—
0
15
9
67
1.35
0.38
1.3
1.2
—
—
—
0
0
14
107
1.31
0.37
1.4
1.8
2.74
3.48
ug/l
—
9
88
5
37
1.35
0.37
1.2
1.1
91.80
94.87
%
—
5
31
13
168
0.77
0.35
2.0
1.4
95.80
169.46
au/ml
—
5
47
21
255
0.82
0.35
1.3
1.3
—
—
—
0
0
14
109
1.29
0.33
1.4
1.5
—
—
—
0
0
14
109
1.29
0.33
1.0
1.3
—
—
—
0
0
180
1702
1.07
0.33
2.1
1.9
30.21
29.22
s
0.66
173
1649
388
3754
1.05
0.32
3.0
3.0
27.95
32.81
u/l
1.78
373
3550
41
363
1.13
0.29
1.1
1.3
—
—
—
0
0
10
130
0.77
0.29
2.7
3.0
11.20
10.41
mmol/l
—
10
130
7
56
1.25
0.29
1.0
1.0
—
—
—
0
0
60
545
1.11
0.29
1.7
1.8
—
—
—
0
0
17
139
1.23
0.29
1.2
1.5
—
—
—
0
0
44
393
1.12
0.28
1.3
1.8
3.14
4.77
mg/l
0.47
36
305
51
460
1.11
0.28
1.5
1.6
48.40
14.53
u/ml
—
8
91
8
62
1.29
0.28
1.3
1.0
204.38
258.41
mg/l
—
8
51
8
62
1.29
0.28
1.0
1.5
—
—
—
0
0
49
442
1.11
0.27
1.5
1.7
—
—
—
0
0
36
319
1.13
0.26
2.4
2.6
1.65
1.50
mg/l
0.33
29
289
71
769
0.92
0.26
1.8
1.8
3.53
3.52
mmol/l
0.02
54
534
8
67
1.20
0.26
1.6
1.4
73.38
80.27
umol/l
—
8
67
18
213
0.84
0.25
1.4
1.3
—
—
—
0
0
33
292
1.13
0.25
1.5
1.2
—
—
—
0
0
13
105
1.24
0.25
1.5
1.4
—
—
—
0
0
17
142
1.20
0.24
1.7
1.5
—
—
—
0
0
29
255
1.14
0.24
1.3
1.2
3.55
3.78
mmol/l
0.97
29
240
135
1282
1.06
0.24
6.6
6.7
1.15
1.06
mmol/l
0.10
117
1065
99
1052
0.94
0.23
1.4
1.7
1.41
1.44
%
0.13
83
915
19
222
0.85
0.23
1.2
1.4
—
—
—
0
0
5
41
1.22
0.22
4.0
4.6
—
—
—
0
0
14
167
0.84
0.21
1.3
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
29
325
0.89
0.21
1.2
1.5
794.51
1051.86
mu/l
0.91
22
259
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
3.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
64
595
1.08
0.21
1.1
1.0
—
—
—
0
0
18
154
1.17
0.21
1.8
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
1.27
—
0
13
43
393
1.10
0.20
2.9
3.4
31.30
73.50
mg/l
1.59
37
339
19
164
1.16
0.20
1.1
1.1
10.49
2.73
u/ml
0.47
11
85
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
6
48
1.25
0.20
1.2
1.0
1916.00
1750.04
miu/ml
—
6
48
6
48
1.25
0.20
1.0
1.2
—
82.33
—
0
6
22
250
0.88
0.20
4.2
3.6
22.75
25.15
mg/l
0.09
13
166
57
530
1.08
0.19
1.2
1.4
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
35
319
1.10
0.18
2.1
2.6
0.37
0.39
iu/ml
0.10
20
173
7
62
1.13
0.17
1.0
1.1
—
—
—
0
0
7
63
1.11
0.17
1.4
2.2
—
—
—
0
0
39
359
1.09
0.17
2.3
2.7
25.18
25.04
mmol/l
0.08
39
353
15
130
1.16
0.15
1.2
1.4
—
—
—
0
0
10
117
0.85
0.13
4.0
2.4
13.37
13.28
%
—
10
117
9
109
0.82
0.13
2.8
2.1
—
—
—
0
0
10
85
1.18
0.12
1.0
1.0
—
—
—
0
0
17
152
1.12
0.12
1.1
1.1
—
5.28
—
0
22
42
395
1.07
0.12
3.0
3.4
25.34
51.76
mg/l
1.96
35
341
30
323
0.93
0.12
1.0
1.2
1.53
1.58
g/l
0.56
30
323
27
249
1.09
0.12
3.9
3.4
0.88
0.83
nmol/l
0.14
19
208
890
8955
0.98
0.11
22.9
19.7
13.62
13.68
%
0.87
885
8831
66
632
1.05
0.11
6.6
8.2
16.18
15.74
%
0.93
66
608
36
340
1.06
0.09
1.5
1.5
0.03
0.09
iu/ml
0.86
13
65
115
1121
1.03
0.08
2.3
2.1
0.21
0.21
g/l
0.28
107
1058
8
78
1.03
0.07
1.3
1.4
—
—
—
0
0
16
147
1.09
0.07
1.0
1.1
—
—
—
0
0
31
294
1.06
0.07
1.4
1.4
—
—
—
0
0
11
99
1.11
0.06
1.5
1.4
—
—
—
0
0
29
305
0.95
0.06
1.6
1.7
—
—
—
0
0
51
525
0.97
0.05
1.3
1.5
—
—
—
0
0
13
123
1.06
0.01
1.1
1.1
—
—
—
0
0
894
8946
1.00
0.00
25.1
20.4
330.85
330.85
g/l
0.00
889
8896
17
174
0.98
0.00
1.3
1.3
—
—
—
0
0
31
308
1.01
0.00
1.2
1.3
225.00
236.71
miu/ml
0.07
13
145
15
149
1.01
0.00
1.1
1.1
—
—
—
0
0
10
103
0.97
0.00
1.2
1.5
62.20
55.74
ug/l
—
10
103
12
123
0.98
0.00
2.0
1.6
—
—
—
0
0
35
347
1.01
0.00
3.3
3.3
1.50
3.45
ratio
1.06
26
195
22
225
0.98
0.00
2.0
2.4
78.67
102.77
ug/min
—
9
127
6
59
1.02
0.00
1.3
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
6.96
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
21
210
1.00
-0.00
1.2
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
59.56
—
0
9
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
51
0.98
-0.00
1.0
1.1
—
—
—
0
0
319
3190
1.00
-0.00
3.8
3.6
0.50
0.04
estimate
0.79
109
998
5
53
0.94
-0.00
2.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
22.34
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
97
0.93
-0.00
1.0
1.1
—
—
—
0
0
8
86
0.93
-0.00
1.4
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
2.52
—
0
5
5
53
0.94
-0.00
2.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
22.49
—
0
7
8
86
0.93
-0.00
1.4
1.5
—
—
—
0
0
8
83
0.96
-0.00
1.4
1.3
7.45
9.17
mmol/l
—
8
78
0
7
0.00
-0.00
0.0
1.0
—
9.01
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
81
0.99
-0.00
1.0
1.2
1.50
2.12
mmol/l
—
8
75
5
55
0.91
-0.00
2.6
2.5
—
—
—
0
0
5
59
0.85
-0.00
1.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
37.30
—
0
7
Mortality – FinRegistry
↥Association
Association between endpoint E4_GOITREDIFF and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_GOITREDIFF | 1.08 [0.97, 1.2] | 0.166 |
| Birth year | 0.994 [0.99, 1.0] | 0.153 |
During the follow-up period (1.1.1998 — 31.12.2019), 753 out of 4980 females with E4_GOITREDIFF died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_GOITREDIFF | 1.199 [1.0, 1.44] | 0.05 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 221 out of 886 males with E4_GOITREDIFF died.
Mortality risk
Mortality risk for people of age
years, who have E4_GOITREDIFF.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.093% | 0.187% |
| 5 | 0.582% | 1.244% |
| 10 | 1.489% | 3.239% |
| 15 | 2.926% | 5.961% |
| 20 | 5.264% | 10.079% |
Relationships between endpoints
↥Index endpoint: E4_GOITREDIFF – Nontoxic diffuse goitre
GWS hits: 6
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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