This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Abnormal findings in cerebrospinal fluid
R18_ABNORMAL_FINDI_CEREBROS_FLUID
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
126 |
4. Check minimum number of eventsNone |
126 |
5. Include endpointsNone |
126 |
6. Filter based on genotype QC (FinnGen only) |
109 |
Control definitions (FinnGen only)
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- R8[3-9]
- Name in latin
- Reperta abnormia in liquore cerebrospinali
Similar endpoints
↥List of similar endpoints to
Abnormal findings in cerebrospinal fluid
based on the number of shared cases.
Similar with more cases:
- Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
- Any operation in hilmo
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 109 | 70 | 39 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | 49.56 | 48.79 | 50.94 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 113
- Matched controls
- 1130
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
TAB00
NOMESCO Finland
Lumbar puncture
11.0
26.2
33
41
R83.8
ICD-10 Finland
Abnormal findings in cerebrospinal fluid, Other abnormal findings
+∞
26.0
24
*
R83.4
ICD-10 Finland
Abnormal findings in cerebrospinal fluid, Abnormal immunological findings
+∞
26.0
24
*
R83.6
ICD-10 Finland
Abnormal findings in cerebrospinal fluid, Abnormal cytological findings
+∞
22.7
21
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
7.1
18.1
33
62
R83.0
ICD-10 Finland
Abnormal findings in cerebrospinal fluid, Abnormal level of enzymes
+∞
12.7
12
*
R83.9
ICD-10 Finland
Abnormal findings in cerebrospinal fluid, Unspecified abnormal finding
+∞
12.7
12
*
R83.2
ICD-10 Finland
Abnormal findings in cerebrospinal fluid, Abnormal level of other drugs, medicaments and biological substances
+∞
11.7
11
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.8
10.6
28
72
Z01.8
ICD-10 Finland
Other specified special examinations
3.8
10.2
42
151
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
13.1
9.4
16
14
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
40.2
9.2
11
*
R51.80
ICD-10 Finland
Headache
3.6
9.2
40
148
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.1
7.9
67
362
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
20.1
7.8
11
6
N02AX02
ATC
tramadol; systemic, rectal
2.9
7.4
63
339
G35
ICD-10 Finland
Multiple sclerosis
21.7
7.3
10
5
N06AA09
ATC
amitriptyline; systemic
4.6
7.2
19
48
ZX120
NOMESCO Finland
Intravenous
4.2
7.1
21
58
H02AB06
ATC
prednisolone; systemic
2.9
6.8
70
410
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.6
6.6
25
83
TPH04
NOMESCO Finland
Cathetrisation of vein
3.1
6.5
35
144
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
7.0
6.4
15
24
109
Kela drug reimbursment
Multiple sclerosis
28.4
6.3
8
*
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
28.4
6.3
8
*
R83.5
ICD-10 Finland
Abnormal findings in cerebrospinal fluid, Abnormal microbiological findings
+∞
6.3
6
*
AA1AD
NOMESCO Finland
CT of head and brain
2.8
6.1
43
204
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
33
30
15.13
32.67
1.8
1.3
506.38
22.80
e6/l
0.72
26
25
18
11
19.16
12.14
1.6
1.1
0.60
0.49
ratio
—
8
6
29
79
4.59
10.22
1.4
1.3
—
33.44
—
0
7
15
10
17.05
9.83
1.2
1.0
—
—
—
0
0
18
19
11.03
9.70
1.2
1.2
—
—
—
0
0
18
19
11.03
9.70
1.2
1.2
—
—
—
0
0
17
16
12.27
9.68
1.2
1.1
—
—
—
0
0
15
12
14.19
9.17
1.8
1.5
—
—
—
0
0
92
579
4.17
8.81
11.7
11.2
4.29
3.99
e9/l
0.70
79
510
80
469
3.42
8.38
8.2
7.1
1.21
1.22
mmol/l
0.37
66
411
75
424
3.29
8.35
6.8
4.4
33.61
36.17
g/l
2.31
70
401
25
73
4.11
7.94
7.9
4.0
1.22
1.23
mmol/l
0.42
25
62
11
6
20.08
7.77
1.2
1.5
—
—
—
0
0
59
309
2.90
7.21
2.5
2.1
109.40
143.43
u/l
0.60
53
296
18
44
4.68
7.12
2.7
2.2
35.00
46.64
u/l
1.60
18
39
86
556
3.29
7.07
6.7
4.9
6.75
6.53
mmol/l
0.37
81
526
12
12
11.02
6.72
1.3
1.1
—
—
—
0
0
54
282
2.75
6.47
3.8
2.7
0.49
0.34
e6/l
0.20
43
199
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
11
10
12.02
6.45
1.1
1.4
—
—
—
0
0
56
306
2.65
6.03
5.1
2.9
0.00
0.00
estimate
-0.00
31
90
13
20
7.19
5.75
1.7
1.3
—
—
—
0
0
77
502
2.68
5.63
4.0
3.1
116.87
101.74
ug/l
0.28
72
474
34
155
2.71
5.13
4.1
2.3
11.70
13.42
umol/l
0.78
28
141
23
86
3.10
4.95
3.7
3.1
—
—
—
0
0
7
5
14.78
4.64
1.1
1.0
—
—
—
0
0
77
530
2.42
4.59
4.9
3.6
0.00
14.25
estimate
0.50
34
114
12
24
5.46
4.46
3.1
1.3
—
—
—
0
0
77
537
2.36
4.35
4.9
3.6
0.00
0.00
estimate
-0.00
32
110
75
525
2.27
4.09
5.1
3.6
0.00
0.00
estimate
-0.00
34
113
62
406
2.17
3.95
5.3
3.4
0.00
0.00
estimate
-0.00
32
97
6
5
12.56
3.80
1.3
1.8
—
—
—
0
0
10
21
5.12
3.65
2.2
3.0
1.80
3.00
index
—
5
12
15
54
3.05
3.41
5.7
9.8
25.59
25.27
mmol/l
0.12
15
54
6
7
8.96
3.30
1.0
1.1
—
—
—
0
0
50
319
2.02
3.24
3.2
2.5
48.89
53.48
u/l
0.82
45
295
54
357
1.98
3.15
5.2
3.1
43.41
40.43
ng/l
0.04
41
229
25
124
2.30
3.06
4.6
8.0
105.64
104.34
mmol/l
1.12
25
124
5
5
10.37
3.00
1.0
1.4
—
—
—
0
0
5
5
10.37
3.00
1.4
2.0
—
—
—
0
0
5
5
10.37
3.00
1.2
1.6
—
—
—
0
0
106
934
3.18
2.91
26.0
14.0
87.31
84.98
ml/min/173m2
0.57
101
861
59
410
1.92
2.91
2.1
2.0
100.23
97.30
pmol/l
0.23
29
229
9
23
4.16
2.84
1.4
1.2
—
—
—
0
0
45
289
1.93
2.78
5.9
3.8
0.00
0.00
estimate
-0.00
32
105
23
115
2.26
2.75
3.7
2.8
5.38
6.20
umol/l
0.24
18
102
20
96
2.32
2.62
6.1
9.6
0.92
1.03
mmol/l
0.04
15
83
5
7
7.40
2.57
1.2
1.6
—
—
—
0
0
33
195
1.98
2.57
1.6
1.8
438.14
448.97
pmol/l
0.07
28
172
14
57
2.66
2.56
1.8
1.5
—
—
—
0
0
28
158
2.03
2.47
1.6
1.8
—
—
—
0
0
13
52
2.69
2.46
4.4
2.0
4.16
1.44
mmol/l
—
7
41
5
8
6.47
2.39
2.0
3.8
460.40
444.75
u/ml
—
5
8
108
979
3.33
2.37
27.6
14.2
17.10
21.59
mg/l
1.11
96
790
99
853
2.30
2.27
33.6
17.3
13.93
13.53
%
1.31
99
847
5
9
5.75
2.23
2.8
2.0
1.21
1.21
mmol/l
—
5
9
35
221
1.85
2.21
2.0
1.8
0.72
1.15
mg/l
0.57
27
179
18
91
2.16
2.09
2.8
2.7
0.21
0.22
g/l
0.15
18
83
40
268
1.76
2.07
1.4
1.4
0.75
1.64
u/ml
0.65
16
77
9
34
2.79
1.91
1.2
1.3
—
—
—
0
0
33
214
1.77
1.89
1.4
1.3
3.22
7.80
u/ml
0.71
18
87
31
198
1.78
1.86
3.9
3.0
29.47
248.70
ng/l
0.80
24
141
7
25
2.92
1.68
1.3
1.5
—
—
—
0
0
6
20
3.11
1.60
5.7
2.3
69.85
9.19
pmol/l
—
6
20
9
38
2.48
1.49
1.2
1.6
—
—
—
0
0
6
22
2.82
1.45
1.2
1.4
—
—
—
0
0
9
40
2.36
1.44
1.2
1.4
—
—
—
0
0
33
231
1.61
1.39
1.5
1.3
39.12
29.12
iu/ml
0.17
12
70
0
39
0.00
1.36
0.0
1.4
—
250.50
—
0
21
36
261
1.56
1.31
2.8
2.9
826.80
716.57
ng/l
0.14
30
222
5
112
0.42
1.21
2.6
4.9
26.60
32.85
%
—
5
73
31
222
1.55
1.18
2.5
1.6
—
—
—
0
0
59
484
1.46
1.16
2.9
2.8
—
—
estimate
—
0
0
23
154
1.62
1.15
2.8
2.5
1.38
2.92
e6/l
0.71
12
67
17
105
1.73
1.14
1.6
1.8
—
—
—
0
0
7
32
2.26
1.10
1.1
2.3
102.57
96.41
%
—
7
32
12
68
1.86
1.05
1.2
1.3
109.03
584.10
u/ml
0.71
12
63
10
53
1.97
1.05
2.9
11.1
23.50
24.54
mmol/l
—
10
53
5
22
2.33
1.04
1.0
1.3
—
—
—
0
0
17
110
1.64
0.97
1.5
1.7
—
—
—
0
0
6
27
2.29
0.95
1.3
2.8
—
—
—
0
0
6
27
2.29
0.95
1.0
1.2
—
—
—
0
0
24
171
1.51
0.93
2.7
2.4
0.64
0.71
e6/l
0.08
13
85
24
171
1.51
0.93
1.3
1.3
—
—
—
0
0
15
97
1.63
0.86
2.8
2.9
43.13
28.65
u/l
0.68
15
81
11
65
1.77
0.86
2.2
1.8
—
—
—
0
0
6
31
1.99
0.85
1.0
1.2
—
—
—
0
0
6
31
1.99
0.85
1.0
1.2
—
—
—
0
0
8
46
1.79
0.84
1.6
1.8
—
—
—
0
0
20
140
1.52
0.84
2.3
1.6
1776.53
1231.98
nmol/l
1.57
15
107
0
25
0.00
0.80
0.0
2.0
—
—
—
0
0
5
24
2.13
0.75
1.0
1.1
—
—
—
0
0
9
56
1.66
0.74
6.7
11.9
0.64
0.63
%
—
9
56
9
57
1.63
0.73
1.0
1.3
—
—
—
0
0
9
58
1.60
0.72
6.7
11.8
1.33
1.39
%
—
9
58
5
94
0.51
0.70
2.6
6.9
—
—
—
0
0
7
42
1.71
0.70
1.4
1.2
—
2.76
—
0
8
18
130
1.46
0.66
1.9
1.6
1.58
1.45
%
0.22
12
112
7
44
1.63
0.66
2.0
1.1
0.88
0.89
g/l
—
7
44
98
924
1.46
0.63
6.1
5.8
39.79
38.59
mmol/mol
0.53
92
873
108
1041
1.85
0.58
19.6
11.5
24.60
26.53
u/l
0.88
108
1018
6
36
1.70
0.57
1.0
1.2
—
—
—
0
0
6
37
1.66
0.56
1.3
1.4
—
—
—
0
0
7
49
1.46
0.47
2.3
2.5
0.83
1.38
%
—
7
49
8
60
1.36
0.41
1.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
5
36
1.41
0.38
2.0
1.9
—
—
—
0
0
6
46
1.32
0.33
3.3
2.7
232.83
96.54
ng/l
—
6
41
97
936
1.26
0.31
4.9
4.8
6.22
5.87
mmol/l
0.52
92
878
11
85
1.33
0.29
2.9
1.9
—
—
—
0
0
7
94
0.73
0.23
1.6
1.9
2.86
3.52
mmol/l
—
7
68
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
6
51
1.19
0.20
4.5
3.1
23.60
24.50
mmol/l
—
6
51
19
213
0.87
0.16
4.5
3.8
20.94
23.17
%
—
9
87
9
82
1.11
0.15
3.7
2.3
0.15
0.21
e6/l
—
9
75
46
435
1.10
0.14
1.8
1.9
1.38
1.39
mmol/l
0.05
36
371
26
239
1.11
0.13
2.2
2.4
—
—
—
0
0
5
44
1.14
0.10
1.0
1.1
1.54
1.62
g/l
—
5
44
33
312
1.08
0.10
3.5
4.0
16.37
13.60
mg/mmol
0.08
18
183
70
684
1.06
0.07
4.7
3.4
—
—
—
0
0
12
131
0.91
0.06
1.6
2.0
3.01
3.35
ratio
0.58
12
110
15
156
0.96
0.00
5.9
1.9
—
—
—
0
0
15
156
0.96
0.00
3.9
2.6
0.89
0.74
ug/l
—
10
93
14
142
0.98
0.00
5.1
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
1.33
—
0
6
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: R18_ABNORMAL_FINDI_CEREBROS_FLUID – Abnormal findings in cerebrospinal fluid
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).