No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
571 |
4. Check minimum number of eventsNone |
571 |
5. Include endpointsNone |
571 |
6. Filter based on genotype QC (FinnGen only) |
330 |
Control definitions (FinnGen only)
- Control exclude
- C3_CANCER, C3_CANCER_WIDE
Extra metadata
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Chronic myeloid leukaemia, including Hilmo
based on the number of shared cases.
Similar with more cases:
- Myeloproliferative diseases
- Primary_lymphoid and hematopoietic malignant neoplasms
- Liquid cancers
- Liquid cancers, including Hilmo
- Malignant neoplasm
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 330 | 151 | 179 |
| Unadjusted period prevalence (%) | 0.07 | 0.05 | 0.08 |
| Median age at first event (years) | 60.89 | 57.86 | 63.44 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 347
- Matched controls
- 3470
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
+∞
307.7
342
*
XW000
NOMESCO Finland
Bone marrow biopsy
145.4
307.7
194
30
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
4503599627370496.0
307.7
311
*
189
Kela drug reimbursment
Imatinib
+∞
218.6
186
*
L01XE01
ATC
[U] imatinib
+∞
177.9
155
*
9863/3-C42.1
ICD-O-3
Chronic myeloid leukemia, NOS, of bone marrow
+∞
175.3
153
*
M04AA01
ATC
allopurinol; systemic
16.6
160.7
196
252
L01EA01
ATC
imatinib; oral
+∞
141.6
126
*
316
Kela drug reimbursment
Imatinib
+∞
111.6
101
*
L01XX05
ATC
hydroxycarbamide; oral
1395.1
108.5
100
*
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
+∞
79.3
73
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
8.3
71.8
120
208
212
Kela drug reimbursment
Gout
25.3
71.5
52
24
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
177.7
69.9
71
5
152
Kela drug reimbursment
Nilotinib
+∞
66.9
62
*
WW500
NOMESCO Finland
Blood transfusion
20.0
55.0
44
25
L03AA02
ATC
filgrastim; parenteral
+∞
53.5
50
*
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
+∞
52.4
49
*
L01XX28
ATC
[U] imatinib
+∞
50.2
47
*
A04AA01
ATC
ondansetron; systemic, rectal
14.6
48.7
46
36
150
Kela drug reimbursment
Dasatinib
+∞
48.0
45
*
328
Kela drug reimbursment
Nilotinib
+∞
43.7
41
*
L01XE08
ATC
[U] nilotinib
+∞
41.5
39
*
L01XE06
ATC
[U] dasatinib
+∞
41.5
39
*
127
Kela drug reimbursment
Transplant complication
66.0
40.4
46
8
L01EA03
ATC
nilotinib; oral
+∞
40.4
38
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
8.5
38.4
54
74
R50.9
ICD-10 Finland
Fever, unspecified
4.7
34.1
99
272
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
11.0
31.4
35
35
L01EA02
ATC
dasatinib; oral
+∞
29.6
28
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
28.5
27
*
9875/3-C42.1
ICD-O-3
Chronic myelogenous leukemia, BCR/ABL positive of bone marrow
+∞
28.5
27
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
27.5
26
*
324
Kela drug reimbursment
Dasatinib
+∞
26.4
25
*
A03FA01
ATC
metoclopramide; systemic, rectal
4.2
25.9
84
247
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.6
25.5
70
181
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.3
25.1
221
1210
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.5
24.3
51
105
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
+∞
23.2
22
*
Z51.5
ICD-10 Finland
Palliative care
6.9
22.8
37
59
WW200
NOMESCO Finland
Immunization
9.4
22.7
28
32
JN4AD
NOMESCO Finland
Body CT examination
5.5
22.3
46
93
L04AA01
ATC
[U] ciclosporin
41.6
22.1
27
7
JN4BD
NOMESCO Finland
Extensive body CT
6.7
22.0
37
61
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
53.6
21.4
25
5
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
21.0
20
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
17.2
21.0
33
21
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
+∞
20.0
19
*
170
Kela drug reimbursment
Bosutinib
+∞
20.0
19
*
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
+∞
20.0
19
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
211.6
19.8
20
*
D72.9
ICD-10 Finland
Disorder of white blood cells, unspecified
58.5
19.2
22
*
C92.9
ICD-10 Finland
Myeloid leukaemia, unspecified
+∞
18.9
18
*
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
+∞
18.9
18
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.6
18.6
37
72
A05AA02
ATC
ursodeoxycholic acid; oral
16.5
18.3
29
19
N02AA05
ATC
oxycodone; systemic
3.4
18.2
80
284
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
55.7
18.2
21
*
130
Kela drug reimbursment
Malignant tumour
+∞
17.9
17
*
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
189.3
17.7
18
*
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
189.3
17.7
18
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
44.6
17.5
21
5
B73
ICPC
Leukaemia
+∞
16.8
16
*
L03AB05
ATC
interferon alfa-2b; parenteral
+∞
16.8
16
*
C95.9
ICD-10 Finland
Leukaemia, unspecified
+∞
16.8
16
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
6.4
16.8
29
49
B03XA02
ATC
darbepoetin alfa; parenteral
19.1
16.7
25
14
H02AB02
ATC
dexamethasone; systemic
17.8
16.3
25
15
C03CA01
ATC
furosemide; systemic
2.6
16.2
143
737
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
15.7
15
*
L01EA04
ATC
bosutinib; oral
+∞
15.7
15
*
360
Kela drug reimbursment
Bosutinib
+∞
15.7
15
*
B03XA01
ATC
erythropoietin; parenteral
167.2
15.6
16
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.5
15.5
60
196
115
Kela drug reimbursment
Breast cancer
+∞
14.7
14
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.8
14.6
49
145
WZC00
NOMESCO Finland
Treatment plan or consultation
2.5
14.4
121
603
121
Kela drug reimbursment
Severe hypofunction of sexual glands
10.7
13.7
26
26
ZX090
NOMESCO Finland
Other technic of radiotherapy
78.3
13.7
15
*
J01MA14
ATC
moxifloxacin; systemic
3.5
13.7
51
162
116
Kela drug reimbursment
Prostate cancer
+∞
13.6
13
*
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
+∞
13.6
13
*
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
145.5
13.5
14
*
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
41.8
13.3
16
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
4.2
13.2
37
96
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
72.6
12.7
14
*
L04AD01
ATC
ciclosporin; systemic
21.0
12.6
18
9
C90.0
ICD-10 Finland
Multiple myeloma
+∞
12.6
12
*
C82.1
ICD-10 Finland
Follicular lymphoma grade II
+∞
12.6
12
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
12.6
12
*
A04AA02
ATC
granisetron; systemic, transdermal
134.7
12.5
13
*
ZX120
NOMESCO Finland
Intravenous
4.0
12.5
37
100
J05AB11
ATC
valaciclovir; oral
2.8
12.3
72
297
R72
ICD-10 Finland
Abnormality of white blood cells, not elsewhere classified
39.1
12.3
15
*
XX3DW
NOMESCO Finland
Time consuming IT work
4.7
12.2
29
66
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.6
11.9
82
368
L03AA04, ,
ATC
+∞
11.5
11
*
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
+∞
11.5
11
*
J01MA12
ATC
levofloxacin; systemic
2.6
11.2
78
350
D64.9
ICD-10 Finland
Anaemia, unspecified
3.0
11.2
54
200
WF002
NOMESCO Finland
Radical radiotherapy
44.8
11.0
13
*
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
44.8
11.0
13
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.4
10.6
27
65
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
10.5
10
*
L01XE14
ATC
[U] bosutinib
+∞
10.5
10
*
WW306
NOMESCO Finland
Transfer of stem cells from foreign registered donator
+∞
10.5
10
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
10.5
10
*
9960/3-C42.1
ICD-O-3
Myeloproliferative neoplasm, NOS, of bone marrow
+∞
10.5
10
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
10.5
10
*
2051A
ICD-9 Finland
Myeloid leukaemia, Chronic
+∞
10.5
10
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
10.5
10
*
A07AA02
ATC
nystatin; oral
3.9
10.4
32
89
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
5.5
10.2
20
38
Y84
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
15.2
10.1
16
11
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.1
9.9
28
73
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
26.9
9.9
13
5
Y84.8
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
26.9
9.9
13
5
A01AB04
ATC
amphotericin B; local oral
3.8
9.7
31
88
J02AC03
ATC
voriconazole; systemic
56.6
9.7
11
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
9.5
9.6
19
21
UJF32
NOMESCO Finland
Coloscopy
2.2
9.6
102
550
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
102.7
9.5
10
*
L02AE02
ATC
leuprorelin; implant, parenteral
31.0
9.5
12
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
9.4
9
*
306
Kela drug reimbursment
Erythropoietin and darbepoetin
+∞
9.4
9
*
C93.1
ICD-10 Finland
Chronic myelomonocytic leukaemia
+∞
9.4
9
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
9.4
9
*
9945/3-C42.1
ICD-O-3
Chronic myelomonocytic leukemia, NOS, of bone marrow
+∞
9.4
9
*
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
+∞
9.4
9
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
9.3
122
712
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.3
9.3
37
122
TPX10
NOMESCO Finland
Implantation of vascular injection port
9.9
8.9
17
18
J05AB01
ATC
aciclovir; systemic
2.2
8.4
86
453
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
8.4
8
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
+∞
8.4
8
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
8.4
8
*
D47.3
ICD-10 Finland
Essential (haemorrhagic) thrombocythaemia
+∞
8.4
8
*
373
Kela drug reimbursment
Ponatinib
+∞
8.4
8
*
L02BB03
ATC
bicalutamide; oral
+∞
8.4
8
*
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
+∞
8.4
8
*
JN3AD
NOMESCO Finland
Abdominal CT examination
2.6
8.3
52
221
A41.9
ICD-10 Finland
Sepsis, unspecified
4.2
8.2
22
55
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.2
8.2
34
115
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
8.8
7.9
16
19
NK6AN
NOMESCO Finland
Total body bone isotope imaging
46.0
7.7
9
*
L03AA13
ATC
pegfilgrastim; parenteral
46.0
7.7
9
*
B01AB10
ATC
tinzaparin; parenteral
2.8
7.7
39
148
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
4.0
7.6
22
58
L02BA01
ATC
tamoxifen; oral
81.8
7.4
8
*
L02BG04
ATC
letrozole; oral
13.8
7.4
12
9
ZX112
NOMESCO Finland
Subcutaneous
13.8
7.4
12
9
WW409
NOMESCO Finland
Other aferesis
+∞
7.3
7
*
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
+∞
7.3
7
*
1529, ,
Kela drug reimbursment
+∞
7.3
7
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
7.3
7
*
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
+∞
7.3
7
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
7.3
7
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
7.3
7
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
7.3
111
675
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.6
7.1
24
71
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
7.1
105
632
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
6.1
7.0
18
31
H02AB04
ATC
methylprednisolone; systemic
2.3
7.0
61
300
JN6AD
NOMESCO Finland
CT of torso and neck
14.1
6.9
11
8
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
6.9
80
441
D75.2
ICD-10 Finland
Essential thrombocytosis
40.9
6.8
8
*
D70.89
ICD-10 Finland
Neutropenic splenomegaly
40.9
6.8
8
*
H02AB06
ATC
prednisolone; systemic
1.8
6.7
170
1208
JFB31
NOMESCO Finland
Laparoscopic right hemicolectomy
71.1
6.4
7
*
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
71.1
6.4
7
*
ZXD05
NOMESCO Finland
Urgent procedure
1.9
6.4
105
650
L01BB02
ATC
mercaptopurine; oral
11.3
6.3
11
10
C92.2
ICD-10 Finland
Atypical chronic myeloid leukaemia, BCR/ABL- negative
+∞
6.3
6
*
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
+∞
6.3
6
*
C92.7
ICD-10 Finland
Other myeloid leukaemia
+∞
6.3
6
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
6.3
6
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
6.3
6
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
6.3
6
*
L01BC06
ATC
capecitabine; oral
+∞
6.3
6
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
6.3
6
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
6.3
6
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
6.3
6
*
C95.1
ICD-10 Finland
Chronic leukaemia of unspecified cell type
+∞
6.3
6
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
+∞
6.3
6
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
6.2
70
381
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
6.1
98
601
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.8
6.0
30
113
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
116
22
78.70
210.97
2.3
1.3
—
—
—
0
0
170
266
11.57
116.20
4.3
2.0
70.72
66.64
e9/l
0.59
131
201
97
0
+∞
106.94
17.0
0.0
—
—
—
0
0
91
0
+∞
99.94
13.7
0.0
—
—
—
0
0
215
781
5.61
56.14
7.0
2.3
337.28
355.04
umol/l
1.60
208
688
104
210
6.64
52.51
2.3
2.2
9.13
11.18
g/l
5.13
98
195
284
1438
6.37
46.06
19.1
3.9
11.30
12.15
umol/l
0.52
279
1358
295
1554
6.99
45.29
31.2
6.2
4.20
4.26
e9/l
0.04
281
1361
68
116
7.05
39.90
1.8
1.8
1.23
1.50
g/l
1.41
61
106
44
44
11.31
39.74
1.1
1.2
158.78
173.83
au/ml
—
9
15
47
56
9.55
37.37
1.6
1.9
—
—
—
0
0
267
1455
4.62
34.81
15.7
5.8
1.21
1.21
mmol/l
0.09
239
1266
29
0
+∞
30.68
1.1
0.0
—
—
—
0
0
32
29
12.05
30.65
2.4
1.3
33.38
33.10
pg
0.10
32
29
238
1281
3.73
29.55
14.2
5.2
1.21
1.21
mmol/l
0.08
230
1166
37
60
6.78
22.40
2.6
1.4
—
—
—
0
0
37
61
6.67
22.04
2.9
1.3
—
—
—
0
0
24
5
51.33
20.43
6.0
1.8
2.35
1.40
%
—
24
5
27
36
8.05
19.36
2.8
1.4
—
—
—
0
0
24
32
7.98
17.18
1.0
1.0
—
—
—
0
0
41
94
4.81
17.11
2.4
1.6
1.59
1.78
ug/l
0.06
41
84
109
486
2.81
16.52
3.0
1.8
—
—
—
0
0
256
1736
2.81
16.30
8.6
4.3
6.66
6.68
mmol/l
0.06
250
1646
200
1222
2.50
15.54
5.9
2.3
—
—
estimate
—
0
0
28
52
5.77
14.73
1.1
1.2
358.25
225.86
u/ml
1.18
20
28
58
191
3.45
14.73
1.9
1.4
—
—
—
0
0
87
372
2.79
14.04
2.6
1.7
—
—
—
0
0
213
1388
2.38
13.66
13.6
15.4
1.19
1.28
inr
2.00
188
1163
203
1308
2.33
13.19
4.6
2.9
242.51
127.75
ug/l
3.47
198
1218
81
347
2.74
12.94
2.8
1.8
—
—
—
0
0
20
13
16.24
12.77
4.1
1.9
0.56
0.69
e9/l
0.47
20
13
33
81
4.40
12.61
1.7
1.3
—
—
—
0
0
136
756
2.31
12.34
3.0
2.2
2.63
2.79
mg/l
0.40
129
645
36
101
3.86
11.51
2.4
3.7
—
—
—
0
0
116
633
2.25
10.74
5.9
2.0
—
—
—
0
0
22
26
8.96
10.71
1.5
1.4
—
—
—
0
0
159
1001
2.09
10.08
6.3
2.8
38.84
35.18
u/l
0.26
153
943
9
0
+∞
9.41
1.0
0.0
—
—
—
0
0
25
63
4.20
9.22
2.0
1.2
—
—
—
0
0
112
635
2.13
9.21
2.0
1.7
1.47
1.05
mg/l
0.95
94
485
19
24
8.31
8.97
2.9
1.5
—
—
—
0
0
27
76
3.77
8.58
1.6
1.3
—
—
—
0
0
19
28
7.11
8.18
3.0
1.4
—
—
—
0
0
70
349
2.26
7.81
8.8
6.4
11.96
11.59
kpa
0.26
65
339
69
343
2.26
7.75
8.9
6.6
0.96
1.10
mmol/l
0.09
53
286
16
20
8.33
7.68
2.9
2.0
—
—
—
0
0
17
24
7.39
7.57
3.1
1.1
—
—
—
0
0
17
24
7.39
7.57
3.1
1.1
—
—
—
0
0
17
24
7.39
7.57
3.1
1.1
—
—
—
0
0
21
54
4.07
7.54
2.2
1.3
—
—
—
0
0
18
41
4.58
7.52
2.1
1.3
—
—
—
0
0
148
999
1.84
6.96
4.0
3.2
1805.72
1308.04
ng/l
0.37
140
846
23
69
3.50
6.68
1.4
1.2
1.43
1.30
ratio
0.38
16
42
92
539
1.96
6.64
1.8
1.8
1245.59
1158.64
nmol/l
0.39
85
411
139
932
1.82
6.60
5.0
3.1
572.41
123.62
e6/l
0.38
121
704
24
76
3.32
6.42
1.7
1.3
225.50
324.07
ug/g
1.39
14
49
43
188
2.47
6.42
4.0
3.6
0.50
1.95
mmol/l
1.39
30
137
42
182
2.49
6.38
2.1
1.7
—
—
—
0
0
11
10
11.31
6.34
1.6
2.7
16.18
13.90
%
—
11
10
6
0
+∞
6.27
1.5
0.0
19.33
—
u/ml
—
6
0
23
73
3.30
6.13
1.9
2.1
127.56
132.35
g/l
0.26
16
54
10
8
12.82
6.12
1.8
3.5
—
—
—
0
0
138
947
1.76
5.91
2.0
1.7
19.48
20.57
nmol/l
0.37
127
801
37
157
2.52
5.88
1.6
1.5
—
—
—
0
0
11
12
9.42
5.83
1.6
1.8
—
—
—
0
0
11
12
9.42
5.83
1.6
1.8
—
—
—
0
0
50
244
2.23
5.82
3.3
2.1
0.22
0.21
g/l
0.46
45
221
14
24
6.03
5.59
1.0
1.0
—
—
—
0
0
10
10
10.25
5.56
1.8
1.2
—
—
—
0
0
10
10
10.25
5.56
1.8
1.2
—
—
—
0
0
15
29
5.36
5.45
1.7
1.6
—
—
—
0
0
9
8
11.51
5.32
4.4
1.0
—
—
—
0
0
9
8
11.51
5.32
4.4
1.0
—
—
—
0
0
9
8
11.51
5.32
4.3
1.0
—
—
—
0
0
18
54
3.46
5.24
2.1
1.1
—
—
—
0
0
10
13
7.88
4.88
4.2
1.2
—
—
—
0
0
10
13
7.88
4.88
4.2
1.2
—
—
—
0
0
10
13
7.88
4.88
4.2
1.2
—
—
—
0
0
10
13
7.88
4.88
4.2
1.2
—
—
—
0
0
117
801
1.70
4.87
4.9
3.0
0.63
0.38
e6/l
0.48
101
573
14
29
4.98
4.86
1.9
1.5
—
—
—
0
0
12
22
5.61
4.64
1.8
1.3
20620.50
23165.25
e6/l
—
6
12
8
8
10.20
4.54
2.0
1.1
—
—
—
0
0
8
8
10.20
4.54
2.0
1.1
—
—
—
0
0
8
8
10.20
4.54
1.0
1.0
—
—
—
0
0
13
28
4.78
4.41
1.8
1.2
—
—
—
0
0
19
66
2.99
4.40
1.9
1.4
—
—
—
0
0
161
1224
1.59
4.29
4.1
3.8
37.59
69.11
ng/l
0.55
133
897
196
1571
1.57
4.08
4.1
3.8
0.00
0.01
estimate
0.50
34
289
193
1543
1.57
4.06
3.9
3.8
0.00
0.00
estimate
-0.00
40
300
87
575
1.68
4.04
4.2
2.0
2.43
2.44
mmol/l
0.13
87
508
15
49
3.15
3.85
3.4
2.3
8.88
8.96
pmol/l
0.01
15
49
71
450
1.73
3.83
4.9
3.0
2.07
2.41
e6/l
0.16
44
206
256
2201
1.62
3.80
6.7
4.3
13.70
11.29
mm/h
1.95
248
2045
7
8
8.90
3.79
1.7
1.3
2.09
5.13
nmol/l
—
7
8
11
24
4.70
3.77
1.4
1.1
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
19
73
2.70
3.70
2.8
2.2
0.34
0.40
iu/ml
0.30
13
36
8
12
6.79
3.69
1.4
1.0
—
—
—
0
0
193
1563
1.53
3.69
3.9
3.8
0.00
0.00
estimate
-0.00
39
307
45
251
1.91
3.67
2.9
2.2
32.88
34.38
u/l
0.13
40
207
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
6
6
10.15
3.51
1.2
3.7
103.67
160.67
%
—
6
6
26
123
2.20
3.29
5.2
4.2
24.29
24.98
mmol/l
0.48
26
117
6
8
7.61
3.06
1.7
1.5
—
—
—
0
0
5
5
10.12
2.98
2.6
1.4
63.00
67.60
nmol/l
—
5
5
23
109
2.19
2.92
3.9
1.6
—
—
—
0
0
7
13
5.47
2.88
1.0
1.2
—
—
—
0
0
114
865
1.47
2.80
3.8
3.7
0.00
0.01
estimate
0.50
33
284
12
39
3.15
2.80
2.1
1.1
—
—
—
0
0
12
39
3.15
2.80
2.1
1.1
—
—
—
0
0
12
39
3.15
2.80
2.1
1.1
—
—
—
0
0
12
39
3.15
2.80
1.1
1.5
—
—
—
0
0
17
72
2.43
2.77
2.4
1.3
—
—
—
0
0
6
10
6.08
2.71
6.8
1.7
1.00
1.00
index
—
6
10
174
1436
1.42
2.70
2.6
2.1
93.92
96.33
pmol/l
0.28
120
713
17
73
2.40
2.69
4.7
3.0
4.64
1.15
index
1.22
11
34
11
36
3.12
2.59
2.2
1.1
—
—
—
0
0
12
44
2.79
2.57
1.3
1.5
—
—
—
0
0
12
44
2.79
2.57
1.3
1.5
—
—
—
0
0
10
31
3.29
2.54
1.1
1.8
—
—
—
0
0
11
37
3.04
2.51
2.2
1.1
—
—
—
0
0
11
37
3.04
2.51
2.2
1.1
—
—
—
0
0
50
323
1.64
2.51
5.7
3.0
2.19
1.90
mmol/l
0.15
40
277
37
220
1.76
2.50
5.3
2.0
55.87
65.85
ml/min/173m2
1.18
23
86
9
26
3.53
2.50
1.4
1.6
1105.56
879.04
mg
—
9
26
194
1654
1.39
2.39
2.8
2.8
—
—
—
0
0
5
8
6.32
2.38
1.0
1.0
—
—
—
0
0
8
22
3.70
2.38
1.1
1.3
65.13
39.50
u/l
—
8
16
21
105
2.06
2.36
2.2
1.5
—
—
—
0
0
70
497
1.51
2.35
4.4
2.8
1.49
1.19
e6/l
0.33
45
257
12
47
2.61
2.29
2.0
2.2
59331.60
11829.72
u/l
—
5
18
42
266
1.66
2.28
3.8
2.8
—
—
—
0
0
6
15
4.05
2.04
1.7
3.1
991.67
713.00
u/ml
—
6
15
303
2829
1.56
2.04
41.6
13.7
19.05
24.03
mg/l
2.14
285
2273
13
57
2.33
2.00
1.2
1.6
—
—
—
0
0
143
1186
1.35
1.98
4.0
3.7
0.00
0.01
estimate
0.50
31
234
6
16
3.80
1.94
1.3
1.1
—
—
—
0
0
81
615
1.41
1.92
6.0
4.1
110.06
408.12
ng/l
1.92
68
494
258
2346
1.39
1.92
53.6
16.6
14.71
13.53
%
26.08
258
2321
93
729
1.38
1.83
4.2
4.0
1.02
1.02
kg/l
0.20
67
465
5
13
3.89
1.72
19.0
1.3
190.60
204.38
u/l
—
5
13
5
13
3.89
1.72
1.0
1.5
—
—
—
0
0
5
13
3.89
1.72
3.4
1.4
—
—
—
0
0
6
21
2.89
1.51
6.8
1.8
16.00
13.30
index
—
6
10
5
16
3.15
1.44
1.4
1.3
—
—
—
0
0
7
29
2.44
1.40
1.3
1.1
126.71
101.69
pmol/l
—
7
29
16
89
1.84
1.39
1.9
1.2
—
—
—
0
0
28
184
1.57
1.37
3.3
2.5
0.59
0.64
%
0.57
28
184
242
2226
1.29
1.36
4.7
4.0
15.27
14.87
pmol/l
1.63
236
2024
9
42
2.17
1.34
2.2
2.4
1.20
1.19
mmol/l
—
9
42
9
42
2.17
1.34
2.2
2.4
105.78
105.48
mmol/l
—
9
42
24
155
1.59
1.27
3.0
3.7
1.02
1.02
ratio
0.14
24
146
100
835
1.28
1.24
3.6
3.2
0.00
0.00
estimate
-0.00
30
235
15
88
1.74
1.13
1.3
1.5
—
—
—
0
0
77
636
1.27
1.04
1.6
1.8
521.17
30134791.16
pmol/l
0.69
63
521
290
2763
1.30
1.03
36.5
13.1
73.08
79.60
ml/min/173m2
5.24
283
2560
7
35
2.02
1.00
1.6
1.3
—
—
—
0
0
5
23
2.19
0.98
2.6
1.4
0.26
0.31
nmol/l
—
5
16
5
23
2.19
0.98
1.0
1.1
—
—
—
0
0
0
30
0.00
0.97
0.0
1.2
—
—
—
0
0
5
101
0.49
0.91
1.2
1.1
1.74
1.52
g/l
—
5
101
24
169
1.45
0.90
2.8
2.8
24.12
25.08
mmol/l
0.75
24
162
11
64
1.74
0.87
1.1
1.5
—
123.33
—
0
6
284
2948
0.80
0.84
6.9
6.2
2.36
2.65
mmol/l
7.34
278
2731
6
32
1.89
0.82
2.2
1.7
4.50
119.26
u/ml
—
6
32
0
25
0.00
0.79
0.0
1.8
—
—
—
0
0
6
34
1.78
0.76
1.0
1.1
—
—
—
0
0
6
105
0.56
0.62
1.2
1.1
0.80
0.90
g/l
—
6
105
19
140
1.38
0.59
1.2
1.3
—
—
—
0
0
7
114
0.61
0.59
2.6
2.1
—
—
—
0
0
6
35
1.73
0.58
1.2
1.1
—
—
—
0
0
6
36
1.68
0.57
1.8
1.2
0.15
0.20
nmol/l
—
6
28
6
38
1.59
0.54
1.0
1.1
—
—
—
0
0
62
539
1.18
0.54
1.3
1.3
1.15
11.89
u/ml
3.78
22
210
13
92
1.43
0.51
1.2
1.1
—
—
—
0
0
13
92
1.43
0.51
1.2
1.1
—
—
—
0
0
10
142
0.70
0.47
1.0
1.1
—
—
—
0
0
121
1118
1.13
0.46
4.7
4.2
15.22
7.46
mg/mmol
0.72
81
702
5
31
1.62
0.43
1.0
1.3
—
—
—
0
0
207
1979
1.11
0.42
3.7
3.3
68.17
47.23
u/l
1.68
198
1868
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
8.94
—
0
16
5
35
1.43
0.39
1.2
1.2
—
—
—
0
0
5
35
1.43
0.39
2.8
4.5
—
—
—
0
0
21
257
0.81
0.38
1.6
1.5
—
—
—
0
0
16
125
1.29
0.37
2.9
1.9
35.81
41.16
nmol/l
0.39
16
119
282
2883
0.88
0.36
6.2
5.3
1.31
1.45
mmol/l
6.97
275
2663
277
2832
0.89
0.34
6.1
5.3
6.08
6.00
mmol/l
0.54
262
2589
42
371
1.15
0.32
11.1
6.4
—
—
—
0
0
7
54
1.30
0.30
1.1
1.4
—
—
—
0
0
89
950
0.92
0.28
3.9
3.8
22.51
24.38
%
0.55
43
435
8
66
1.22
0.27
1.4
1.3
—
—
—
0
0
133
1274
1.07
0.23
2.0
1.9
1.79
1.35
mmol/l
1.50
120
1065
0
11
0.00
0.21
0.0
1.0
—
0.17
—
0
11
0
13
0.00
0.21
0.0
2.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
8.72
—
0
13
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
119
1142
1.06
0.19
4.0
3.5
7.82
7.76
mmol/l
0.05
100
964
10
81
1.24
0.19
1.3
1.2
—
—
—
0
0
62
582
1.08
0.18
1.3
1.3
16.04
38.38
iu/ml
2.98
19
175
40
370
1.09
0.16
1.4
1.8
1.53
1.50
%
0.11
33
331
16
139
1.16
0.16
1.6
2.6
8.24
8.32
iu/ml
—
5
40
9
80
1.13
0.15
1.2
1.2
—
2.90
—
0
6
63
660
0.94
0.13
1.3
1.3
0.83
1.54
u/ml
0.72
12
195
121
1176
1.04
0.12
4.9
4.1
6.14
1.89
ug/l
0.44
111
1056
65
678
0.95
0.11
2.4
2.8
0.69
0.75
ug/l
0.39
41
433
5
64
0.78
0.08
1.0
1.2
—
14.91
—
0
7
279
2768
1.04
0.08
5.5
4.5
1.59
1.29
mmol/l
1.60
270
2539
8
95
0.84
0.06
2.3
2.0
—
—
—
0
0
269
2672
1.03
0.06
6.1
5.1
1.84
1.94
mu/l
0.76
260
2444
35
340
1.03
0.03
1.6
1.5
—
—
—
0
0
10
93
1.08
0.02
1.2
1.2
—
—
—
0
0
19
183
1.04
0.01
1.2
1.3
25.86
109.97
u/ml
—
8
74
24
246
0.97
0.00
1.5
2.1
—
—
—
0
0
46
459
1.00
0.00
1.7
1.5
—
—
—
0
0
279
2794
0.99
0.00
7.1
6.9
38.59
39.77
mmol/mol
2.03
270
2627
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
-0.00
1.2
1.4
—
—
—
0
0
7
76
0.92
-0.00
1.1
1.2
—
61.20
—
0
8
22
220
1.00
-0.00
1.5
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
62
0.97
-0.00
1.2
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
7.50
—
0
6
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
7.3
—
10.53
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1.16
—
0
5
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: C3_CML_WIDE – Chronic myeloid leukaemia, including Hilmo
GWS hits: 1
This endpoint is excluded (different definition than used in FinnGen).