Polyarteritis Nodosa: ['A necrotizing vasculitis that affects medium-sized arteries, it is usually idiopathic, and may be triggered by viral infections (Hepatitis B, also others). A multisystem disease, it most commonly affects skin (nodules, livedo reticularis) and peripheral nerves; higher morbidity is associated with gastrointestinal, central nervous system, cardiac, and/or other organ involvement. Anti-neutrophil cytoplasmic antibodies (ANCA) are typically negative. [ NCI ]']
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
538 |
4. Check minimum number of eventsNone |
538 |
5. Include endpoints |
580 |
6. Filter based on genotype QC (FinnGen only) |
520 |
Control definitions (FinnGen only)
- Control exclude
- M13_SYSTCONNECT
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M30-M36
- Name in latin
- Polyarteritis nodosa et condiciones cognatae
Similar endpoints
↥List of similar endpoints to
Polyarteritis nodosa and related conditions
based on the number of shared cases.
Similar with more cases:
- Systemic connective tissue disorders
- Autoimmune diseases related-to ILD
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5194 | 2773 | 2381 |
| Only index persons | 3827 | 2036 | 1791 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.08 | 0.07 |
| Only index persons | 0.07 | 0.07 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 43.91 | 57.85 | 27.24 |
| Only index persons | 38.04 | 54.00 | 19.89 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 520 | 312 | 208 |
| Unadjusted period prevalence (%) | 0.10 | 0.11 | 0.10 |
| Median age at first event (years) | 54.48 | 53.01 | 56.68 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 541
- Matched controls
- 5410
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M30.0
ICD-10 Finland
Polyarteritis nodosa
+∞
232.6
206
*
M30.1
ICD-10 Finland
Polyarteritis with lung involvement [Churg-Strauss]
+∞
166.5
151
*
L04AX01
ATC
azathioprine; systemic
20.7
155.0
127
79
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
9.2
120.3
182
283
M30.8
ICD-10 Finland
Other conditions related to polyarteritis nodosa
+∞
95.7
89
*
H02AB06
ATC
prednisolone; systemic
5.7
77.5
399
1783
L04AA06
ATC
mycophenolic acid; systemic
22.2
74.0
56
28
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
7.6
71.7
116
188
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.5
67.1
308
1220
M30.3
ICD-10 Finland
Mucocutaneous lymph node syndrome [Kawasaki]
+∞
61.7
58
*
L04AX03
ATC
methotrexate; systemic
5.8
57.4
123
261
M05BA04
ATC
alendronic acid; oral
5.8
54.0
114
238
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
6.5
47.2
84
148
J32.4
ICD-10 Finland
Chronic pansinusitis
18.8
45.9
37
21
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.0
42.9
105
247
D72.1
ICD-10 Finland
Eosinophilia
83.7
41.6
46
6
J45.1
ICD-10 Finland
Nonallergic asthma
5.2
41.5
96
215
M31.3
ICD-10 Finland
Wegener granulomatosis
+∞
40.1
38
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
6.2
39.2
72
130
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
3.6
38.9
176
646
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
8.2
38.9
54
72
R50.9
ICD-10 Finland
Fever, unspecified
3.8
38.1
149
496
N08.5*M30.0
ICD-10 Finland
Glomerular disorders in polyarteritis nodosa
+∞
38.0
36
*
J45.9
ICD-10 Finland
Asthma, unspecified
3.5
37.4
173
642
TGC00
NOMESCO Finland
Bronchial lavation
8.6
36.8
49
62
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.1
35.8
334
1850
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.7
35.5
71
139
H02AB07
ATC
prednisone; oral
3.9
35.4
128
402
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.1
35.1
115
337
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
58.2
32.7
38
7
UDH02
NOMESCO Finland
Rhinopharyngoscopy
4.9
32.5
79
183
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.7
32.1
125
411
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
5.7
31.3
62
120
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
6.0
30.8
58
107
4461A
ICD-9 Finland
Polyarteritis nodosa and allied conditions, Acute febrile mucocutaneous lymph node syndrome [MCLS]
+∞
30.5
29
*
H02AB04
ATC
methylprednisolone; systemic
3.5
29.1
123
425
P01BA02
ATC
hydroxychloroquine; oral
4.6
28.6
74
180
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.8
28.5
209
988
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
296.1
28.0
28
*
ZX120
NOMESCO Finland
Intravenous
3.9
28.0
92
268
H02AB09
ATC
hydrocortisone; systemic
7.9
27.1
38
51
L01AA01
ATC
cyclophosphamide; systemic
79.4
27.1
30
*
J33.0
ICD-10 Finland
Polyp of nasal cavity
7.2
26.7
41
61
J01MA12
ATC
levofloxacin; systemic
3.1
26.3
142
565
M31.8
ICD-10 Finland
Other specified necrotizing vasculopathies
+∞
26.3
25
*
R03AK08
ATC
formoterol and beclometasone; inhalant
5.6
24.6
49
95
J45.0
ICD-10 Finland
Predominantly allergic asthma
3.8
24.5
84
251
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
+∞
24.1
23
*
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
7.4
23.6
35
50
TDM10
NOMESCO Finland
Puncture of maxillary antrum
5.6
23.6
47
91
UGC12
NOMESCO Finland
Flexible bronchoscopy
4.0
23.5
74
208
M31.7
ICD-10 Finland
Microscopic polyangiitis
+∞
23.1
22
*
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
9.0
23.0
29
34
J33.8
ICD-10 Finland
Other polyp of sinus
8.5
22.8
30
37
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
3.9
22.8
72
203
C03CA01
ATC
furosemide; systemic
2.5
22.5
216
1139
R03DC03
ATC
montelukast; oral
2.9
22.4
132
546
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
+∞
22.0
21
*
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.2
21.4
61
159
L01BA01
ATC
methotrexate; systemic
6.1
21.3
38
66
N03AX16
ATC
[U] pregabalin
2.6
21.0
160
752
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
7.4
21.0
31
44
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
+∞
21.0
20
*
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
+∞
21.0
20
*
M35.3
ICD-10 Finland
Polymyalgia rheumatica
8.1
20.6
28
36
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
5.8
20.4
38
69
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
16.9
20.4
32
20
A11CC03
ATC
alfacalcidol; systemic
6.8
19.4
31
48
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
72.5
18.8
21
*
J45.8
ICD-10 Finland
Mixed asthma
5.4
18.4
37
72
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.3
18.0
74
247
L04AD01
ATC
ciclosporin; systemic
7.9
18.0
25
33
J01FF01
ATC
clindamycin; systemic
2.3
17.7
180
955
R01AD08
ATC
fluticasone; nasal
2.3
17.5
183
981
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
17.5
146
710
GD1AD
NOMESCO Finland
Thorax CT examination
3.7
17.4
58
169
A02BC01
ATC
omeprazole; systemic
2.3
17.1
179
959
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.3
17.1
183
990
J82
ICD-10 Finland
Pulmonary eosinophilia, not elsewhere classified
65.5
16.8
19
*
N08.5*M31.7
ICD-10 Finland
Glomerular disease states in microscopic polyangiitis
+∞
16.8
16
*
4460A
ICD-9 Finland
Polyarteritis nodosa and allied conditions, Polyarteritis nodosa[POLYARTERITIS NODOSA (CLASSICA)]
+∞
16.8
16
*
F02.89*M30.0
ICD-10 Finland
Dementia in polyarteritis nodosa
+∞
16.8
16
*
I77.6
ICD-10 Finland
Arteritis, unspecified
93.0
16.7
18
*
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.7
16.6
108
465
R03AC12
ATC
salmeterol; inhalant
4.0
16.6
49
131
D69.0
ICD-10 Finland
Allergic purpura
20.9
16.6
24
12
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.0
16.6
80
294
J46
ICD-10 Finland
Status asthmaticus
5.9
16.5
30
53
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.8
16.4
52
146
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
16.4
143
706
J01MA02
ATC
ciprofloxacin; systemic
2.1
16.2
231
1395
R03BA02
ATC
budesonide; inhalant
2.4
16.2
131
626
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.8
15.9
37
82
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
27.2
15.7
21
8
N02AX02
ATC
tramadol; systemic, rectal
2.1
15.7
253
1597
R03BA05
ATC
fluticasone; inhalant
2.4
15.6
128
614
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.8
15.6
49
137
TQW80
NOMESCO Finland
Local dermatologic skincare
6.1
15.4
27
46
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
46.4
15.1
18
*
M05BX04
ATC
denosumab; parenteral
3.7
15.1
50
145
Z49.1
ICD-10 Finland
Extracorporeal dialysis
15.6
15.0
24
16
XG410
NOMESCO Finland
Flow-volume spirometry
4.3
15.0
40
99
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.2
14.9
156
830
PAW37
NOMESCO Finland
Biopsy of temporal artery
58.4
14.9
17
*
N18.8
ICD-10 Finland
Other chronic renal failure
6.6
14.7
24
38
L04AA01
ATC
[U] ciclosporin
14.7
14.7
24
17
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.3
14.6
137
695
R03BB04
ATC
tiotropium bromide; inhalant
2.9
14.6
75
285
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
5.7
14.4
27
49
A10AC01
ATC
insulin (human); parenteral
3.0
14.4
68
246
A02BC02
ATC
pantoprazole; systemic
2.1
14.4
378
2819
J01MA14
ATC
moxifloxacin; systemic
3.0
14.3
69
253
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
4.9
14.2
32
69
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.3
14.0
121
591
D64.9
ICD-10 Finland
Anaemia, unspecified
2.8
13.9
77
304
J45
ICD-10 Finland
Asthma
2.8
13.8
74
287
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.9
13.8
68
252
44600
ICD-8 Finland
Polyarteritis nodosa and allied conditions, Polyarteritis nodosa
+∞
13.6
13
*
M31.1
ICD-10 Finland
Thrombotic microangiopathy
+∞
13.6
13
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.8
13.4
75
298
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.4
13.4
34
81
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
13.2
110
528
A46
ICD-10 Finland
Erysipelas
2.4
13.0
99
457
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.9
12.9
67
255
N30.1
ICD-10 Finland
Interstitial cystitis (chronic)
12.0
12.9
23
20
R03AC02
ATC
salbutamol; inhalant
2.0
12.9
320
2297
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.6
12.8
81
342
XG474
NOMESCO Finland
Exhalation nntrogen oxide
4.6
12.8
31
71
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.8
12.7
71
281
S97
ICPC
Chronic ulcer skin
3.1
12.7
55
189
KA1AE
NOMESCO Finland
Kidney ultrasound examination
5.7
12.7
24
44
R03AC13
ATC
formoterol; inhalant
3.5
12.6
44
132
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.3
12.6
50
163
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
12.6
120
610
R03DX09
ATC
mepolizumab; parenteral
+∞
12.5
12
*
M31.0
ICD-10 Finland
Hypersensitivity angiitis
+∞
12.5
12
*
N085, M318,
ICD-10 Finland
+∞
12.5
12
*
297, ,
Kela drug reimbursment
+∞
12.5
12
*
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
20.6
12.5
18
9
3028
Kela drug reimbursment
Mepolizumab
133.0
12.5
13
*
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
27.4
12.1
16
6
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
3.4
12.0
44
136
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.5
11.9
42
127
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
11.8
173
1031
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.0
11.8
34
89
M81.4
ICD-10 Finland
Drug-induced osteoporosis
30.8
11.7
15
5
WX892
NOMESCO Finland
Monitored bed care
2.9
11.6
58
216
XW000
NOMESCO Finland
Bone marrow biopsy
3.9
11.6
35
95
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
11.5
124
659
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
+∞
11.5
11
*
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
+∞
11.5
11
*
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
4.6
11.3
27
61
J47
ICD-10 Finland
Bronchiectasis
5.1
11.3
24
49
WW200
NOMESCO Finland
Immunization
5.1
11.3
24
49
N06AA09
ATC
amitriptyline; systemic
2.7
11.2
64
256
TK800
NOMESCO Finland
Hemodialysis
8.3
11.2
24
30
J01FA06
ATC
roxithromycin; oral
1.9
11.1
224
1479
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.0
11.1
50
176
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.2
11.0
45
149
Z94.0
ICD-10 Finland
Kidney transplant status
12.3
10.9
19
16
UDM02
NOMESCO Finland
Sinoscopy
5.1
10.8
23
47
R03BA08
ATC
ciclesonide; inhalant
2.7
10.8
60
237
A01AB09
ATC
miconazole; local oral
2.7
10.6
62
251
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.4
10.6
38
116
M13.9
ICD-10 Finland
Arthritis, unspecified
2.9
10.5
50
181
R03BA01
ATC
beclometasone; inhalant
2.3
10.5
87
415
R06AE07
ATC
cetirizine; oral
1.8
10.4
241
1653
L95.8
ICD-10 Finland
Other vasculitis limited to skin
23.9
10.3
14
6
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.7
10.2
56
219
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
3.7
10.2
33
94
SPAT1255
SPAT
Intravenous administration of medicine
3.2
10.2
41
135
G58.7
ICD-10 Finland
Mononeuritis multiplex
40.9
10.0
12
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.3
9.9
87
424
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
17.1
9.9
15
9
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
5.3
9.9
20
39
R02
ICPC
Shortness of breath/dyspnoea
2.2
9.9
87
425
DHA10
NOMESCO Finland
Biopsy of cavity of nose
10.9
9.8
18
17
M05BA07
ATC
risedronic acid; oral
4.0
9.8
28
73
A12AA04
ATC
calcium carbonate; oral
7.6
9.8
22
30
127
Kela drug reimbursment
Transplant complication
8.0
9.7
21
27
A07AA02
ATC
nystatin; oral
2.9
9.6
45
162
R03DA04
ATC
theophylline; systemic, rectal
3.0
9.6
43
151
R03AC03
ATC
terbutaline; inhalant
2.2
9.5
84
410
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.0
9.5
112
612
L88
ICPC
Rheumatoid/seropositive arthritis
3.7
9.5
30
84
UJF30
NOMESCO Finland
Ileoscopy through colon
2.5
9.5
64
278
L95.0
ICD-10 Finland
Livedoid vasculitis
101.7
9.4
10
*
JN6JR
NOMESCO Finland
Extensive PET-CT of whole body metabolism (crown to foot)
101.7
9.4
10
*
H26.3
ICD-10 Finland
Drug-induced cataract
12.6
9.4
16
13
N08.5*M31.0
ICD-10 Finland
Glomerular disorders in Goodpasture's syndrome
+∞
9.4
9
*
GX1L5
NOMESCO Finland
Exhaled nitric oxide analysis
10.9
9.3
17
16
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.7
9.2
29
81
KCV04
NOMESCO Finland
Distension of bladder with fluid
14.0
9.2
15
11
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.7
9.1
51
202
A12BA01
ATC
potassium chloride; oral
3.1
9.1
38
128
J01DC02
ATC
cefuroxime; systemic
3.1
9.1
38
128
DHB20
NOMESCO Finland
Polypectomy of internal nose
7.6
9.0
20
27
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.9
8.9
26
69
N18.0
ICD-10 Finland
End-stage renal disease
11.0
8.8
16
15
Z2446
NOMESCO Finland
Social worker
2.5
8.8
56
236
R01AD01
ATC
beclometasone; nasal
2.1
8.8
90
466
C07AB07
ATC
bisoprolol; oral
1.7
8.7
264
1927
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.9
8.7
26
70
B01AA03
ATC
warfarin; systemic
2.0
8.7
107
593
N03AX12
ATC
[U] gabapentin; oral
2.1
8.7
95
505
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
11.8
8.6
15
13
R06.0
ICD-10 Finland
Dyspnoea
1.8
8.6
154
967
R03AK07
ATC
formoterol and budesonide; inhalant
1.9
8.5
116
666
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
28.0
8.5
11
*
N30.0
ICD-10 Finland
Acute cystitis
2.0
8.5
104
576
J01DB01
ATC
cefalexin; oral
2.0
8.4
444
3781
N06AX21
ATC
duloxetine; oral
2.2
8.4
75
367
AA1AD
NOMESCO Finland
CT of head and brain
1.8
8.4
158
1004
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.1
8.4
23
58
R03DC01
ATC
zafirlukast; oral
5.0
8.4
18
37
4476A
ICD-9 Finland
Other disorders of arteries and arterioles, Arteritis, unspecified
+∞
8.4
8
*
M35.1
ICD-10 Finland
Other overlap syndromes
+∞
8.4
8
*
J99.1*M31.3
ICD-10 Finland
Respiratory disorders in Wegener's granulomatosis
+∞
8.4
8
*
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
3.1
8.4
35
118
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
3.9
8.3
24
63
J01FA10
ATC
azithromycin; systemic
1.7
8.3
308
2364
Z3231
NOMESCO Finland
Registered nurse
1.8
8.3
161
1034
R60.0
ICD-10 Finland
Localized oedema
2.2
8.2
78
393
JN4AD
NOMESCO Finland
Body CT examination
2.3
8.2
68
324
M79.7
ICD-10 Finland
Fibromyalgia
4.1
8.1
22
55
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
8.1
140
866
A02BC05
ATC
esomeprazole; systemic
1.7
8.1
215
1506
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
17.5
8.1
12
7
A12AA12
ATC
[U] calcium acetate
33.9
8.1
10
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.0
8.1
100
555
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
3.0
8.1
36
126
UJF32
NOMESCO Finland
Coloscopy
1.8
8.0
138
853
B03XA02
ATC
darbepoetin alfa; parenteral
6.3
7.9
20
33
A41.9
ICD-10 Finland
Sepsis, unspecified
3.3
7.9
29
90
A10AB05
ATC
insulin aspart; parenteral
2.4
7.9
53
230
DPA30
NOMESCO Finland
Sphenotomy
11.0
7.8
14
13
J01EA01
ATC
trimethoprim; systemic
1.8
7.8
150
957
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.3
7.8
29
91
M31.6
ICD-10 Finland
Other giant cell arteritis
45.6
7.7
9
*
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.4
7.7
56
251
N05CD07
ATC
temazepam; oral
2.2
7.7
72
359
I40.9
ICD-10 Finland
Acute myocarditis, unspecified
18.7
7.6
11
6
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
3.5
7.6
26
77
J01MA06
ATC
norfloxacin; oral
2.1
7.6
80
418
ZXD05
NOMESCO Finland
Urgent procedure
1.7
7.6
169
1125
M05BB03
ATC
alendronic acid and colecalciferol; oral
4.3
7.5
19
45
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
7.5
193
1334
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.8
7.5
119
717
WZC30
NOMESCO Finland
Teaching
2.0
7.4
91
502
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
6.1
7.4
19
32
ZX112
NOMESCO Finland
Subcutaneous
4.1
7.4
20
50
DPA25
NOMESCO Finland
Trephine of frontal sinus through nose
9.5
7.3
14
15
S92.3
ICD-10 Finland
Fracture of metatarsal bone
3.1
7.3
30
100
J31.0
ICD-10 Finland
Chronic rhinitis
2.3
7.3
55
251
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.0
7.3
32
111
318
Kela drug reimbursment
Teriparatide
16.0
7.3
11
7
NH3EA
NOMESCO Finland
Feet X-ray examination with load
4.6
7.2
17
38
E0000UV, ,
ATC
1.6
7.2
227
1652
J01DA06
ATC
[U] cefuroxime
2.0
7.2
84
456
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
8.1
7.1
15
19
A02BC03
ATC
lansoprazole; oral
1.7
7.1
154
1013
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.0
7.1
82
443
UKC02
NOMESCO Finland
Cystoscopy
2.0
7.1
81
436
Z49.0
ICD-10 Finland
Preparatory care for dialysis
10.2
7.1
13
13
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
7.0
272
2077
A07EC01
ATC
sulfasalazine; oral, rectal
2.5
7.0
46
197
L17
ICPC
Foot/toe symptom/complaint
1.7
7.0
168
1138
1XC02, ,
NOMESCO Finland
14.0
6.9
11
8
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.5
6.9
23
67
J01AA02
ATC
doxycycline; systemic
1.7
6.9
396
3331
SPAT1167
SPAT
Insertion of urinary catheter
3.9
6.9
20
53
R03AK11
ATC
formoterol and fluticasone; inhalant
3.9
6.9
20
53
C08CA05
ATC
nifedipine; systemic
2.6
6.7
37
146
SPAT1360
SPAT
Extensive global examination
2.6
6.7
38
152
J32.9
ICD-10 Finland
Chronic sinusitis, unspecified
8.0
6.6
14
18
M05BA01
ATC
etidronic acid; systemic
12.4
6.6
11
9
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
4.2
6.6
17
41
L52
ICD-10 Finland
Erythema nodosum
10.2
6.6
12
12
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.1
6.6
66
339
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
6.5
140
916
N02BF02
ATC
pregabalin; oral
2.5
6.5
41
172
M01AH01
ATC
celecoxib; oral
1.9
6.5
93
539
S18
ICPC
Laceration/cut
1.6
6.5
244
1838
B07.9
ICD-10 Finland
Verruca simplex
3.2
6.5
25
80
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
4.0
6.5
18
46
ZXE00
NOMESCO Finland
One hour or less
1.6
6.5
207
1501
ZXD20
NOMESCO Finland
Day surgery
2.0
6.4
71
377
M79.6
ICD-10 Finland
Pain in limb
1.6
6.4
231
1723
49300
ICD-8 Finland
Asthma, bronchiale
3.8
6.4
19
51
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
6.4
282
2204
SPAT1301
SPAT
No procedures
1.7
6.4
166
1142
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.1
6.4
61
307
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.3
6.4
24
76
UDC00
NOMESCO Finland
Ear microscopy
2.3
6.3
49
226
M79.0
ICD-10 Finland
Rheumatism, unspecified
3.5
6.3
21
61
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.6
6.3
37
150
4930B
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA CUM EXACERBATIONE]
11.2
6.3
11
10
137
Kela drug reimbursment
Uraemia requiring dialysis
9.4
6.3
12
13
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.3
6.3
49
227
TK810
NOMESCO Finland
Hemofiltration
18.3
6.3
9
5
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
6.3
89
515
N08.5*M31.1
ICD-10 Finland
Glomerular disorders in thrombotic thrombocytopenic purpura
+∞
6.3
6
*
N085, M319,
ICD-10 Finland
+∞
6.3
6
*
M30
ICD-10 Finland
Polyarteritis nodosa and related conditions
+∞
6.3
6
*
M05.2
ICD-10 Finland
Rheumatoid vasculitis
+∞
6.3
6
*
I77.9
ICD-10 Finland
Disorder of arteries and arterioles, unspecified
+∞
6.3
6
*
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
+∞
6.3
6
*
4460B
ICD-9 Finland
Polyarteritis nodosa and allied conditions, Polyarteritis nodosa[POLYARTERITIS NODOSA CUM INFILTRATIONE PULMONUM]
+∞
6.3
6
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
6.2
194
1395
R53
ICD-10 Finland
Malaise and fatigue
1.7
6.2
146
978
L28
ICPC
Limited function/disability (L)
1.8
6.2
104
634
R01AD09
ATC
mometasone; nasal
1.6
6.2
232
1743
ZX100
NOMESCO Finland
Oral
5.9
6.2
16
28
D02AE01
ATC
carbamide; topical
2.5
6.2
38
158
N02AA05
ATC
oxycodone; systemic
1.8
6.2
100
603
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.1
6.2
58
290
J01FA15
ATC
telithromycin; oral
2.2
6.2
52
249
L04AD02
ATC
tacrolimus; systemic
7.8
6.2
13
17
R01AD05
ATC
budesonide; nasal
2.4
6.1
43
190
E000006, ,
ATC
2.4
6.1
42
184
C08CA01
ATC
amlodipine; oral
1.6
6.1
197
1428
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
3.7
6.1
19
53
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.7
6.1
19
53
I42.0
ICD-10 Finland
Dilated cardiomyopathy
4.0
6.0
17
44
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
112
67
20.82
138.74
2.6
1.1
46.67
—
titre
—
6
0
156
353
5.80
68.69
5.6
3.0
9.63
10.30
g/l
1.01
150
327
101
160
7.53
63.38
3.9
1.4
12.76
5.31
iu/ml
1.18
29
31
88
151
6.77
50.83
1.4
1.1
0.24
3.41
u/ml
—
5
8
57
58
10.87
50.67
1.6
1.1
—
—
—
0
0
120
308
4.72
44.21
2.3
1.2
262.75
292.61
u/ml
0.10
114
285
63
95
7.37
40.81
1.3
1.2
—
—
—
0
0
62
94
7.32
39.95
6.5
7.1
419.70
123.36
iu/ml
—
10
11
83
180
5.27
37.09
1.3
2.3
36.51
39.53
u/l
0.55
76
159
138
461
3.68
34.83
2.9
1.9
301.46
386.52
nmol/l
5.56
132
431
114
338
4.01
34.17
2.3
2.8
64.72
66.94
g/l
2.00
104
312
141
498
3.48
32.46
4.1
4.7
238.25
258.78
u/l
0.57
134
478
124
408
3.65
31.80
9.9
7.5
10.10
9.37
mmol/l
0.49
119
390
66
139
5.27
30.32
1.7
1.5
0.16
0.15
iu/ml
0.02
12
21
156
618
3.14
29.44
9.8
6.2
1.06
1.07
mmol/l
0.24
148
570
51
87
6.37
29.24
1.6
1.4
—
—
—
0
0
66
147
4.97
28.38
2.9
2.9
—
—
—
0
0
35
41
9.06
27.80
2.0
1.6
—
—
—
0
0
62
135
5.06
27.35
2.0
1.6
—
—
—
0
0
397
2626
2.92
27.30
20.1
9.5
4.81
4.09
e9/l
8.31
381
2293
214
1042
2.74
27.30
5.2
2.6
4.23
5.90
e6/l
0.87
205
943
54
109
5.39
25.93
1.6
1.2
1.43
2.69
u/ml
—
8
7
55
113
5.30
25.90
1.6
1.4
—
—
—
0
0
54
110
5.34
25.66
1.6
1.2
3.60
3.63
u/ml
—
8
9
70
180
4.32
25.12
2.3
1.9
0.56
3.08
ug/l
0.95
64
160
59
134
4.82
24.72
2.0
1.5
—
—
—
0
0
353
2264
2.61
24.65
12.5
7.4
1.21
1.21
mmol/l
0.13
307
1969
328
2041
2.54
24.29
10.6
6.6
1.21
1.21
mmol/l
0.31
318
1885
41
68
6.44
24.09
1.4
1.5
—
—
—
0
0
314
1928
2.50
23.73
9.0
4.9
33.55
35.82
g/l
7.98
303
1813
54
119
4.93
23.43
2.7
3.9
2.43
2.47
ratio
0.02
27
64
56
132
4.62
22.39
2.7
4.1
37.25
67.85
mg/l
0.57
41
110
56
132
4.62
22.39
2.7
4.1
57.44
93.42
mg/l
0.35
42
110
166
774
2.65
22.37
2.7
1.9
—
—
—
0
0
91
305
3.38
22.21
4.9
4.2
1.83
1.69
mmol/l
0.12
75
218
321
2032
2.43
22.08
3.7
2.5
79.89
76.64
nmol/l
1.30
308
1823
241
1345
2.43
22.05
3.3
2.1
245.95
300.16
u/l
0.20
227
1276
49
107
4.94
21.46
1.4
1.4
294.80
271.30
u/ml
0.15
31
54
258
1505
2.37
21.10
6.4
3.3
26.93
94.18
e6/l
0.87
223
1150
46
97
5.09
20.97
1.7
1.4
—
—
—
0
0
42
83
5.40
20.58
2.2
1.7
—
—
—
0
0
145
656
2.65
20.56
4.1
2.5
20.11
22.68
%
1.76
138
622
44
92
5.12
20.24
1.5
1.4
—
—
—
0
0
66
191
3.80
20.04
1.8
2.1
1.60
1.40
g/l
0.86
55
176
158
755
2.54
19.94
3.8
2.5
10.98
13.14
umol/l
3.75
149
711
151
708
2.57
19.81
3.9
2.4
2.24
2.33
g/l
0.96
142
659
29
42
7.24
19.27
1.4
1.2
85.00
74.00
titre
—
6
5
225
1291
2.27
18.53
6.2
3.2
0.33
0.48
e6/l
0.71
191
937
25
33
7.89
17.96
1.9
1.3
1.54
0.16
u/ml
0.58
18
19
92
350
2.96
17.96
5.1
4.2
5.07
5.13
kpa
0.24
87
340
93
363
2.89
17.30
6.7
4.1
103.33
79.83
ng/l
1.42
85
322
228
1351
2.19
17.00
4.2
3.3
2001.57
1332.31
ng/l
0.49
212
1165
183
1008
2.23
16.22
2.1
1.5
2.36
2.31
g/l
0.13
138
612
85
329
2.88
16.00
2.1
1.6
—
—
—
0
0
39
90
4.59
15.95
1.7
1.1
101.20
26.55
u/ml
—
5
8
145
729
2.35
15.93
3.5
3.9
0.80
0.82
mmol/l
0.97
140
686
33
67
5.18
15.66
1.8
1.4
—
—
—
0
0
119
552
2.48
15.61
2.5
1.9
—
—
—
0
0
426
3303
2.36
15.13
12.7
4.0
15.90
11.70
mm/h
5.33
415
3070
121
578
2.41
14.82
2.4
1.8
—
—
—
0
0
31
64
5.08
14.44
1.6
1.2
5.33
1.33
u/ml
0.86
15
24
31
64
5.08
14.44
1.7
1.4
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
42
111
4.02
14.42
4.0
3.1
0.38
0.35
iu/ml
0.23
28
61
338
2430
2.04
14.08
7.0
3.8
0.00
0.00
estimate
-0.00
106
509
340
2452
2.04
14.01
7.0
3.9
13.83
3.11
estimate
0.35
109
522
362
2678
2.06
13.80
7.1
5.2
6.80
6.66
mmol/l
0.45
353
2515
178
1023
2.10
13.78
1.9
1.8
1.17
1.35
mg/l
0.44
146
809
132
674
2.27
13.77
2.4
2.1
29.33
29.34
s
0.01
127
660
341
2474
2.02
13.66
7.0
3.9
0.00
0.62
estimate
0.50
104
486
38
98
4.09
13.48
1.4
1.5
115.17
145.98
au/ml
0.60
12
34
298
2069
1.98
13.47
21.8
11.2
0.00
0.00
e9/l
0.02
270
1696
297
2073
1.96
13.08
17.3
12.8
1.26
1.24
inr
0.31
267
1726
21
34
6.39
12.55
1.6
1.4
—
—
—
0
0
29
65
4.66
12.27
1.7
1.2
2.93
3.36
u/ml
0.16
15
28
212
1344
1.95
12.18
6.9
3.9
0.00
0.00
estimate
0.50
103
478
183
1112
1.98
11.84
3.3
2.9
335.54
341.44
umol/l
0.27
163
983
234
1551
1.90
11.62
3.6
3.4
2.32
2.36
mmol/l
3.55
224
1388
421
3384
2.10
11.61
16.6
7.9
77.28
80.49
u/l
0.88
414
3193
324
2388
1.89
11.49
8.1
6.5
11.65
11.34
umol/l
0.10
319
2275
43
135
3.37
11.49
2.6
2.6
0.05
1.05
g/l
1.82
36
117
146
839
2.01
10.95
1.4
1.3
40.24
31.61
iu/ml
0.40
56
254
252
1734
1.85
10.94
6.5
3.8
33.59
40.04
ng/l
0.51
193
1228
23
49
4.86
10.33
2.3
2.0
—
—
—
0
0
97
487
2.21
10.33
6.6
4.0
1.80
1.75
mmol/l
0.06
92
414
21
26
8.36
9.91
1.5
1.4
—
—
—
0
0
134
771
1.98
9.90
1.4
1.3
12.92
12.92
u/ml
0.00
49
297
379
3016
1.86
9.71
7.5
4.7
7978.53
1844.78
e6/l
0.42
15
46
297
2199
1.78
9.69
4.7
2.9
203.57
110.27
ug/l
2.23
288
2051
31
88
3.68
9.64
4.1
3.5
4.89
4.96
kpa
0.20
31
88
35
109
3.36
9.48
1.3
1.6
—
—
—
0
0
128
736
1.97
9.43
1.8
1.7
1224.80
1197.03
nmol/l
0.12
106
560
224
1537
1.78
9.43
4.0
3.3
44.25
33.62
u/l
0.44
208
1457
19
22
8.91
9.36
1.5
1.4
—
—
—
0
0
85
423
2.20
9.20
2.3
2.5
0.20
0.22
g/l
0.71
78
396
19
23
8.52
9.13
1.5
1.4
—
—
—
0
0
23
55
4.32
9.00
2.3
1.9
—
—
—
0
0
19
39
5.01
8.90
1.1
1.1
—
—
—
0
0
17
18
9.71
8.83
1.4
3.0
1535.06
840.00
u/ml
0.75
17
18
20
28
7.37
8.81
1.1
1.1
61.80
30.07
mg/l
0.78
14
22
19
25
7.83
8.71
1.5
1.2
—
—
—
0
0
223
1555
1.74
8.69
6.1
3.4
7.26
7.57
mmol/l
0.48
195
1319
12
6
20.41
8.50
1.3
1.3
—
—
—
0
0
201
1368
1.75
8.50
6.2
3.2
0.00
0.07
estimate
0.55
90
415
87
451
2.11
8.47
4.4
3.3
—
—
—
0
0
39
141
2.90
8.25
1.6
1.3
—
—
—
0
0
38
136
2.93
8.19
2.2
1.5
—
—
—
0
0
18
38
4.87
8.17
1.1
1.1
—
—
—
0
0
14
12
11.94
8.11
2.0
1.3
2.64
1.48
ratio
1.34
14
12
182
1218
1.74
8.09
3.3
2.2
2.98
2.94
mg/l
0.09
169
1053
19
43
4.54
7.95
2.5
1.6
—
—
—
0
0
19
43
4.54
7.95
2.5
1.6
—
—
—
0
0
19
43
4.54
7.95
2.5
1.6
—
—
—
0
0
204
1420
1.70
7.81
3.2
2.6
54.66
64.72
u/l
1.17
194
1330
20
34
6.07
7.75
1.8
2.9
—
—
—
0
0
19
44
4.44
7.74
1.4
1.4
3987.50
2000.81
e6/l
0.51
14
31
94
519
1.98
7.68
6.8
9.1
10.86
12.26
kpa
2.64
87
503
15
17
9.04
7.58
1.2
1.2
—
—
—
0
0
206
1449
1.68
7.52
7.7
4.2
18.54
10.09
mg/mmol
1.12
147
920
166
1114
1.71
7.16
5.5
4.2
91.22
90.57
%
0.12
159
1094
66
328
2.15
7.13
5.8
8.9
24.62
24.69
mmol/l
0.06
66
328
19
34
5.75
7.12
1.6
2.9
929.89
1122.21
mg
0.19
19
34
42
172
2.56
7.03
2.1
1.6
—
—
—
0
0
91
512
1.93
7.01
6.9
9.2
0.94
0.82
mmol/l
0.09
79
425
17
27
6.46
6.99
1.0
1.0
—
—
—
0
0
20
53
3.88
6.86
4.7
3.7
—
—
—
0
0
51
235
2.29
6.62
1.6
1.4
—
—
—
0
0
15
22
6.98
6.55
1.0
1.0
1.28
1.11
u/l
—
9
15
246
1859
1.59
6.48
6.7
3.8
0.00
0.02
estimate
1.15
91
428
18
35
5.28
6.37
1.1
1.1
—
—
—
0
0
18
35
5.28
6.37
1.1
1.1
—
—
—
0
0
118
742
1.75
6.34
5.1
3.0
2.62
2.62
e6/l
0.00
60
366
135
882
1.71
6.32
4.6
3.9
455.03
304.80
ng/l
0.26
106
685
18
47
3.93
6.31
1.0
1.1
—
—
—
0
0
16
39
4.20
6.12
1.0
1.1
—
—
—
0
0
21
63
3.43
6.06
1.5
1.1
—
—
—
0
0
123
793
1.71
6.02
5.0
2.9
0.86
0.96
e6/l
0.10
65
414
16
40
4.09
5.93
2.7
2.3
—
—
—
0
0
17
34
5.13
5.92
1.1
1.1
—
—
—
0
0
17
34
5.13
5.92
1.1
1.1
—
—
—
0
0
17
45
3.87
5.85
1.0
1.1
—
—
—
0
0
13
19
6.98
5.76
1.2
1.1
—
—
—
0
0
51
254
2.11
5.49
2.0
1.7
—
—
—
0
0
89
538
1.78
5.43
2.3
3.3
10.53
8.12
umol/l
0.26
81
476
34
143
2.47
5.42
1.5
1.2
—
—
—
0
0
11
14
7.99
5.36
1.2
1.0
—
—
—
0
0
12
18
6.79
5.28
3.1
1.8
—
—
—
0
0
14
27
5.29
5.11
1.0
1.1
—
—
—
0
0
10
13
7.81
4.87
1.2
1.0
94.80
101.69
%
—
10
13
10
13
7.81
4.87
1.4
2.5
—
—
—
0
0
16
38
4.31
4.86
1.5
1.5
131739.13
59766.35
e6/l
—
8
20
23
84
2.82
4.84
5.7
3.8
9.34
9.12
pmol/l
0.03
23
84
95
610
1.68
4.66
7.8
7.4
102.79
104.20
mmol/l
2.22
95
610
63
359
1.85
4.65
2.4
1.4
—
—
—
0
0
24
92
2.68
4.62
2.0
1.4
—
—
—
0
0
24
92
2.68
4.62
2.0
1.4
—
—
—
0
0
11
18
6.21
4.62
3.3
1.8
—
—
—
0
0
11
18
6.21
4.62
3.3
1.8
—
—
—
0
0
12
23
5.31
4.48
1.2
1.1
114.26
215.02
iu/ml
0.97
12
23
36
172
2.17
4.33
3.0
1.8
—
—
—
0
0
10
16
6.34
4.31
1.0
1.0
—
—
—
0
0
12
25
4.88
4.20
3.1
1.6
—
—
—
0
0
12
25
4.88
4.20
3.1
1.6
—
—
—
0
0
12
25
4.88
4.20
3.1
1.6
—
—
—
0
0
12
25
4.88
4.20
3.1
1.6
—
—
—
0
0
22
85
2.66
4.19
4.1
3.2
0.83
0.90
nmol/l
0.22
17
71
17
57
3.05
4.16
1.4
1.3
—
—
—
0
0
31
143
2.24
4.07
1.9
1.3
—
—
—
0
0
261
2135
1.43
4.06
3.7
2.8
—
—
estimate
—
0
0
72
446
1.71
4.02
2.5
2.5
31.75
143.25
u/l
0.51
61
369
56
324
1.81
3.95
4.0
3.4
226.78
203.82
ng/l
0.14
51
293
14
43
3.32
3.93
1.2
1.2
—
—
—
0
0
14
43
3.32
3.93
1.2
1.2
—
—
—
0
0
26
114
2.35
3.84
2.2
1.3
—
—
—
0
0
6
5
12.11
3.77
2.0
1.4
—
—
—
0
0
7
9
7.86
3.57
1.1
1.4
—
—
—
0
0
23
99
2.38
3.55
2.5
2.4
46.89
66.24
ug/min
0.40
18
60
18
69
2.66
3.50
1.3
1.3
—
—
—
0
0
15
52
2.94
3.49
1.1
1.3
—
—
—
0
0
9
18
5.07
3.38
3.0
6.0
—
—
—
0
0
11
29
3.85
3.20
1.5
1.3
—
—
—
0
0
11
29
3.85
3.20
1.5
1.3
—
—
—
0
0
31
159
2.01
3.16
2.0
1.7
—
—
—
0
0
5
5
10.08
2.98
1.0
1.0
—
—
—
0
0
5
5
10.08
2.98
1.0
1.0
—
—
—
0
0
54
338
1.66
2.93
4.7
2.6
56.06
64.38
ml/min/173m2
0.89
31
141
11
32
3.49
2.91
1.4
1.0
—
—
—
0
0
15
58
2.63
2.89
2.3
2.6
31.00
32.52
pg
0.51
15
58
9
22
4.14
2.89
1.0
1.0
—
—
—
0
0
7
13
5.44
2.87
1.0
1.3
—
—
—
0
0
473
4426
1.55
2.87
38.4
15.1
23.22
23.48
mg/l
0.07
438
3631
55
349
1.64
2.84
4.2
2.2
5.23
7.06
ug/l
0.56
42
317
16
65
2.51
2.81
1.0
1.1
—
—
—
0
0
23
111
2.12
2.77
2.6
1.5
3087.28
17476.43
e6/l
1.75
18
80
235
1975
1.34
2.76
2.5
2.1
92.38
96.17
pmol/l
0.74
143
1021
5
6
8.40
2.75
1.2
1.3
—
—
—
0
0
10
29
3.49
2.70
2.1
2.3
961.70
503.12
ml
—
10
17
26
134
1.99
2.65
1.3
1.3
—
—
—
0
0
7
15
4.71
2.60
1.4
1.1
—
—
—
0
0
115
873
1.40
2.56
2.8
2.8
2.46
2.45
mmol/l
0.08
105
776
16
69
2.36
2.50
1.2
1.0
0.73
2.40
u/ml
1.04
11
38
15
63
2.42
2.48
1.1
1.1
—
—
—
0
0
161
1308
1.33
2.32
2.1
1.7
19.94
20.46
nmol/l
0.19
142
1113
10
34
2.98
2.29
1.0
1.2
100.00
111.41
pmol/l
—
10
34
8
24
3.37
2.18
5.1
3.7
1.94
1.17
%
—
8
24
6
14
4.32
2.15
1.8
2.6
0.62
0.61
mmol/l
—
6
14
138
1111
1.33
2.10
3.2
2.3
—
—
—
0
0
7
20
3.53
2.06
1.4
1.2
—
—
—
0
0
113
891
1.34
1.98
1.9
1.7
444.36
21974127.57
pmol/l
0.72
99
760
18
91
2.01
1.97
1.4
1.1
0.49
0.76
u/ml
0.31
12
58
5
11
4.58
1.94
1.0
1.2
—
—
—
0
0
8
27
2.99
1.94
1.1
1.5
—
—
—
0
0
8
27
2.99
1.94
1.1
1.5
—
—
—
0
0
18
93
1.97
1.87
1.4
1.4
—
—
—
0
0
8
28
2.88
1.87
2.1
2.2
41.18
89.80
ug/l
—
8
28
30
472
0.61
1.85
1.7
1.9
3.34
3.46
ratio
0.20
17
368
329
2992
1.25
1.80
4.1
3.4
59.37
47.10
u/l
1.46
310
2829
7
23
3.07
1.80
1.7
1.3
—
—
—
0
0
7
23
3.07
1.80
1.7
1.3
—
—
—
0
0
7
23
3.07
1.80
1.0
1.0
1699.43
1412.83
miu/ml
—
7
23
132
1086
1.29
1.69
7.0
3.9
1.02
1.02
kg/l
0.36
102
718
6
19
3.18
1.66
1.0
1.1
—
—
—
0
0
6
19
3.18
1.66
1.8
2.2
—
—
—
0
0
377
3501
1.25
1.63
4.9
4.4
15.10
14.74
pmol/l
1.90
353
3184
22
130
1.72
1.55
3.1
3.1
1.50
2.38
index
—
8
71
8
33
2.45
1.54
1.1
1.3
—
—
—
0
0
22
354
0.61
1.52
1.5
1.7
3.35
3.40
mmol/l
0.07
11
255
12
59
2.06
1.44
1.2
1.0
0.07
0.31
u/ml
—
7
23
5
16
3.14
1.44
6.2
3.4
193.80
197.13
u/l
—
5
16
138
1165
1.25
1.42
1.4
1.3
1.48
1.57
u/ml
0.04
27
321
59
445
1.37
1.40
3.3
4.1
9.98
36.51
ug/l
0.77
42
363
12
60
2.02
1.39
1.2
1.0
—
—
—
0
0
6
24
2.52
1.30
1.2
1.4
85.00
72.63
umol/l
—
6
24
5
18
2.79
1.28
2.4
1.6
64.08
91.14
ng/l
—
5
18
8
35
2.30
1.27
1.1
1.6
—
25.33
—
0
6
12
63
1.93
1.23
1.2
1.1
1.74
1.46
g/l
0.91
12
57
310
2866
1.19
1.22
3.9
3.2
—
—
—
0
0
5
19
2.65
1.22
1.2
4.5
2.38
1.89
ug/l
—
5
19
110
925
1.24
1.18
1.9
1.6
—
—
—
0
0
8
40
2.01
1.12
1.3
1.4
—
—
—
0
0
11
59
1.88
1.08
2.7
1.4
—
—
—
0
0
11
59
1.88
1.08
2.7
1.4
—
—
—
0
0
8
147
0.54
1.05
3.1
1.9
36.00
39.76
nmol/l
—
8
141
11
60
1.85
1.03
2.7
1.4
—
—
—
0
0
5
23
2.18
0.98
1.4
1.3
5.24
6.70
mmol/l
—
5
23
10
174
0.57
0.98
1.3
1.5
—
—
—
0
0
14
85
1.66
0.95
1.4
2.0
4.90
4.67
mmol/24h
0.12
14
75
6
27
2.24
0.93
1.3
1.4
—
—
—
0
0
11
63
1.76
0.90
2.7
1.4
—
—
—
0
0
11
63
1.76
0.90
2.7
1.4
—
—
—
0
0
6
114
0.52
0.83
3.3
1.9
210.50
236.09
pmol/l
—
6
104
357
3736
0.87
0.81
41.9
19.7
330.39
332.44
g/l
3.58
357
3714
19
131
1.47
0.79
1.3
1.1
—
—
—
0
0
19
131
1.47
0.79
1.3
1.1
—
—
—
0
0
7
38
1.85
0.73
1.1
1.4
1.40
1.40
promille
—
7
29
7
38
1.85
0.73
1.1
1.5
—
481.67
—
0
6
422
4081
1.15
0.69
7.6
6.4
39.64
39.26
mmol/mol
0.34
402
3830
199
1838
1.13
0.69
2.1
1.9
1.41
1.35
mmol/l
0.34
176
1556
5
94
0.53
0.67
2.0
1.5
61.80
50.25
ug/l
—
5
94
5
28
1.79
0.66
1.4
1.1
—
—
—
0
0
427
4140
1.15
0.64
31.5
14.8
79.51
82.08
ml/min/173m2
1.37
405
3818
8
130
0.61
0.64
1.6
1.6
—
—
—
0
0
11
71
1.56
0.62
1.2
1.3
—
—
—
0
0
11
164
0.66
0.62
1.3
1.1
1.57
1.54
g/l
0.15
11
164
10
63
1.60
0.62
2.9
1.4
—
—
—
0
0
0
20
0.00
0.60
0.0
1.7
—
45.96
—
0
5
10
64
1.57
0.59
1.7
1.3
0.50
0.56
nmol/l
—
10
58
12
171
0.69
0.55
1.3
1.1
0.84
0.89
g/l
0.48
12
171
6
39
1.54
0.53
1.8
1.9
—
—
—
0
0
422
4118
1.11
0.45
5.9
5.4
1.96
1.92
mu/l
0.25
401
3789
0
16
0.00
0.41
0.0
1.1
—
331.90
—
0
10
8
59
1.36
0.41
1.8
1.3
0.15
0.17
nmol/l
—
8
42
408
4170
0.91
0.39
5.8
5.0
5.89
5.95
mmol/l
0.31
382
3815
5
36
1.39
0.38
1.2
1.3
—
—
—
0
0
28
235
1.20
0.37
1.3
1.3
—
—
—
0
0
29
245
1.19
0.36
4.7
3.9
50.01
47.22
%
0.28
29
238
17
141
1.21
0.26
1.8
1.5
—
—
—
0
0
67
723
0.92
0.25
2.8
3.1
0.66
0.76
ug/l
0.76
42
457
5
38
1.32
0.23
1.2
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
17
145
1.18
0.21
1.2
1.4
339.33
298.65
ug/g
—
6
84
29
259
1.13
0.20
1.0
1.0
—
—
—
0
0
9
113
0.79
0.20
2.0
1.7
—
—
—
0
0
6
49
1.23
0.20
2.8
2.0
13.43
13.35
%
—
6
49
11
133
0.82
0.19
1.2
1.5
1.25
1.22
ratio
—
6
82
11
133
0.82
0.19
1.2
1.5
0.94
0.95
ratio
—
6
82
11
133
0.82
0.19
1.2
1.5
0.90
1.07
ratio
—
6
82
91
958
0.94
0.19
4.6
4.5
20.89
21.86
%
0.18
43
453
6
52
1.16
0.19
1.2
1.3
—
—
—
0
0
11
131
0.84
0.17
1.2
1.5
—
—
—
0
0
419
4237
0.95
0.17
5.5
4.9
1.47
1.47
mmol/l
0.16
398
3938
5
66
0.76
0.17
1.8
1.5
—
—
—
0
0
52
487
1.07
0.16
10.3
6.3
—
—
—
0
0
19
168
1.14
0.16
2.4
1.9
—
—
—
0
0
421
4253
0.95
0.15
5.5
5.0
4.51
4.61
mmol/l
1.28
400
3976
18
159
1.14
0.15
2.7
1.5
339.67
297.79
mu/l
0.42
18
146
9
82
1.10
0.15
2.4
1.8
—
—
—
0
0
36
337
1.07
0.12
1.3
1.2
32.68
144.63
u/ml
5.96
17
136
18
197
0.91
0.10
1.4
1.5
0.10
0.30
mg/l
—
10
89
6
55
1.09
0.09
2.3
2.3
-2.78
0.28
mmol/l
—
6
55
70
724
0.96
0.08
1.6
1.5
—
—
—
0
0
122
1196
1.03
0.07
5.0
5.4
2.24
2.39
ug/l
0.13
110
1082
402
4042
0.98
0.06
4.7
4.2
1.34
1.28
mmol/l
1.07
376
3731
431
4330
0.98
0.05
6.0
5.7
2.56
2.69
mmol/l
2.50
409
4031
18
188
0.96
0.02
1.4
2.4
13224.18
6395.71
u/l
—
9
81
54
549
0.98
0.02
4.7
4.8
34.02
31.97
%
0.71
42
365
11
117
0.94
0.01
1.5
1.2
—
—
—
0
0
14
137
1.02
0.00
1.7
1.4
—
—
—
0
0
28
276
1.02
0.00
2.1
2.2
—
—
—
0
0
53
535
0.99
0.00
2.6
2.2
—
—
—
0
0
57
574
0.99
0.00
2.8
2.3
—
—
—
0
0
55
548
1.00
0.00
1.5
1.7
1.48
1.48
%
0.00
47
479
33
331
1.00
0.00
2.1
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
6.04
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.1
—
55.40
—
0
7
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
21.83
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
49
1.02
-0.00
2.0
3.5
7.16
6.11
nmol/l
—
5
49
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.9
—
35.25
—
0
8
Mortality – FinRegistry
↥Association
Association between endpoint M13_POLYARTERETAL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_POLYARTERETAL | 2.265 [1.92, 2.68] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.11 |
During the follow-up period (1.1.1998 — 31.12.2019), 770 out of 2094 females with M13_POLYARTERETAL died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_POLYARTERETAL | 2.27 [1.8, 2.86] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 372 out of 1721 males with M13_POLYARTERETAL died.
Mortality risk
Mortality risk for people of age
years, who have M13_POLYARTERETAL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.176% | 0.466% |
| 5 | 1.242% | 2.493% |
| 10 | 3.117% | 6.549% |
| 15 | 6.191% | 12.498% |
| 20 | 10.063% | 20.251% |
Relationships between endpoints
↥Index endpoint: M13_POLYARTERETAL – Polyarteritis nodosa and related conditions
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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