Maternal care for known or suspected disproportion

O15_MATERN_CARE_DISPROP

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

only females

313377

2. Check conditions

None

313377

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O33
  • Cause of death: ICD-10 O33

2 out of 7 registries used, show all original rules.

1949

4. Check minimum number of events

None

1949

5. Include endpoints

None

1949

6. Filter based on genotype QC (FinnGen only)

1744

Control definitions (FinnGen only)

Control exclude
O15_MATERN_CARE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF3
Parent code in ICD-10
O30-O48
Name in latin
Cura matris propter disproportionem fetopelvinam notam sive suspectam

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 13757 13757 -
Only index persons 13623 13623 -
Unadjusted period prevalence (%)
Whole population 0.39 0.39 -
Only index persons 0.50 0.50 -
Median age at first event (years)
Whole population - 30.64 -
Only index persons - 30.64 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1744 1744 -
Unadjusted period prevalence (%) 0.62 0.62 -
Median age at first event (years) 30.88 30.88 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1826
Matched controls
18260
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
80.3
307.7
1413
746
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
15.8
307.7
298
223
O33.5
ICD-10 Finland
Maternal care for disproportion due to unusually large fetus
+∞
307.7
408
*
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
16384.0
307.7
955
*
O33.3
ICD-10 Finland
Maternal care for disproportion due to outlet contraction of pelvis
+∞
307.7
341
*
O82.0
ICD-10 Finland
Delivery by elective caesarean section
108.4
307.7
902
163
O33.9
ICD-10 Finland
Maternal care for disproportion, unspecified
+∞
307.7
438
*
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
17.8
307.7
542
423
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
1719.9
304.9
288
*
O33.1
ICD-10 Finland
Maternal care for disproportion due to generally contracted pelvis
+∞
288.4
269
*
O32.1
ICD-10 Finland
Maternal care for breech presentation
412.4
223.5
220
6
O33.4
ICD-10 Finland
Maternal care for disproportion of mixed maternal and fetal origin
+∞
220.4
207
*
O33.2
ICD-10 Finland
Maternal care for disproportion due to inlet contraction of pelvis
+∞
184.6
174
*
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
3.9
180.5
1006
4361
O63.0
ICD-10 Finland
Prolonged first stage (of labour)
13.9
174.6
166
130
O65.4
ICD-10 Finland
Obstructed labour due to fetopelvic disproportion, unspecified
36.0
162.0
102
30
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
4.7
147.8
412
1072
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
4.5
130.5
378
1007
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
5.0
130.1
318
739
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
3.7
129.7
540
1861
8811
FHL
Cesarean section
5.1
122.8
288
645
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
421.0
120.1
119
*
O65.1
ICD-10 Finland
Obstructed labour due to generally contracted pelvis
44.1
114.0
68
16
O48
ICD-10 Finland
Prolonged pregnancy
+∞
111.6
106
*
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
3.2
107.9
600
2439
O33.0
ICD-10 Finland
Maternal care for disproportion due to deformity of maternal pelvic bones
+∞
96.7
92
*
ZXD05
NOMESCO Finland
Urgent procedure
2.8
96.2
722
3424
LGA10
NOMESCO Finland
Sterilisation by destruction or division of Fallopian tubes
13.0
88.5
86
69
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
7.7
87.6
126
173
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
2.8
80.4
545
2414
MAA00
NOMESCO Finland
Amniocentesis
8.7
79.8
103
124
LGA20
NOMESCO Finland
Sterilisation by constriction of Fallopian tubes
12.1
79.5
81
70
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
5.3
74.6
158
320
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
9.0
74.1
93
108
6533B
ICD-9 Finland
Disproportion, Outlet contraction of pelvis[PELVIS ANGUSTA, ANOM APERT INFER,SYNNYTYKSEN AIKANA]
17.0
73.1
61
37
O40
ICD-10 Finland
Polyhydramnios
+∞
71.3
68
*
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
+∞
68.1
65
*
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
+∞
63.9
61
*
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
6.8
59.5
95
146
XMA22
NOMESCO Finland
General examination of pregnant woman
3.3
59.0
250
840
O30.0
ICD-10 Finland
Twin pregnancy
+∞
58.7
56
*
O41.0
ICD-10 Finland
Oligohydramnios
+∞
58.7
56
*
O99.80
ICD-10 Finland
The fear of childbirth
4.0
58.6
179
484
Z36.8
ICD-10 Finland
Other antenatal screening
5.5
58.0
117
226
6531B
ICD-9 Finland
Disproportion, Generally contracted pelvis[PELVIS ANGUSTA,SYNNYTYKSEN AIKANA]
15.1
56.4
50
34
O65.3
ICD-10 Finland
Obstructed labour due to pelvic outlet and mid-cavity contraction
72.3
55.5
63
9
O64.0
ICD-10 Finland
Obstructed labour due to incomplete rotation of fetal head
5.8
55.2
103
185
WX306
NOMESCO Finland
Lumbar epidural anesthesy
3.3
54.2
229
766
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
268.0
51.4
52
*
LGA00
NOMESCO Finland
Sterilisation by ligature of Fallopian tubes
15.4
51.2
45
30
O33.8
ICD-10 Finland
Maternal care for disproportion of other origin
+∞
50.2
48
*
6500B
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
0.3
48.7
119
3829
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
48.2
733
4442
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
+∞
48.1
46
*
SPAT1196
SPAT
Monitoring of normal pregnancy
3.2
47.9
212
728
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
+∞
47.1
45
*
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
2.5
46.6
368
1705
Z30.2
ICD-10 Finland
Sterilization
2.4
46.0
392
1878
WX320
NOMESCO Finland
Spinalanesthesy
2.4
45.9
394
1893
Z32.1
ICD-10 Finland
Pregnancy confirmed
2.6
45.4
305
1308
NE1AG
NOMESCO Finland
MRI pelvimetry with high intensity magnet
416.7
41.3
41
*
Z39.2
ICD-10 Finland
Routine postpartum follow-up
2.4
41.0
335
1568
O61.0
ICD-10 Finland
Failed medical induction of labour
9.0
40.3
50
57
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
209.6
40.0
41
*
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
2.2
38.3
404
2100
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
2.7
37.6
232
950
O64.1
ICD-10 Finland
Obstructed labour due to breech presentation
10.5
36.1
40
39
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
+∞
34.5
33
*
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
+∞
33.4
32
*
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
9.1
33.4
41
46
O65.2
ICD-10 Finland
Obstructed labour due to pelvic inlet contraction
75.6
32.9
37
5
MCA96
NOMESCO Finland
Other caesarean section
35.8
32.9
42
12
MAC96
NOMESCO Finland
Other induction or advancement of labour
4.1
31.7
89
225
W84
ICPC
Pregnancy high risk
4.1
31.2
89
228
Z36.4
ICD-10 Finland
Antenatal screening for fetal growth retardation using ultrasound and other physical methods
4.2
29.2
78
190
O20.0
ICD-10 Finland
Threatened abortion
3.6
29.2
101
296
W92
ICPC
Compl labour/ delivery livebirth
6.6
29.1
47
73
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
2.9
28.7
146
539
O42.1
ICD-10 Finland
Premature rupture of membranes, onset of labour after 24 hours
+∞
28.2
27
*
O32.2
ICD-10 Finland
Maternal care for transverse and oblique lie
78.9
27.8
31
*
SPAT1197
SPAT
Extensive health check-up of expecting family
2.2
27.3
258
1271
MAB20
NOMESCO Finland
Failed external version
+∞
27.1
26
*
O63.1
ICD-10 Finland
Prolonged second stage (of labour)
3.0
27.0
122
421
6534B
ICD-9 Finland
Disproportion, Foetopelvic disproportion[DISPROPORTIO FOETOPELVICA,SYNNYTYKSEN AIKANA]
7.0
26.8
41
60
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
2.6
26.6
161
650
SPAT1379
SPAT
Health check-up of pregnant person
2.3
25.2
202
927
O41.1
ICD-10 Finland
Infection of amniotic sac and membranes
+∞
25.1
24
*
O47.9
ICD-10 Finland
False labour, unspecified
9.8
25.0
29
30
SPAT1357
SPAT
Monitoring of problem during pregnancy
3.8
24.1
74
200
MCA00
NOMESCO Finland
Upper uterine segment caesarean section
87.9
23.7
26
*
O86.0
ICD-10 Finland
Infection of obstetric surgical wound
6.3
23.2
39
63
J01DA01
ATC
[U] cefalexin
1.7
22.6
1204
9814
O82.11
ICD-10 Finland
Childbirth with an emergency caesarean section in an emergency
6.7
22.2
35
53
O36.9
ICD-10 Finland
Maternal care for fetal problem, unspecified
+∞
21.9
21
*
OAB47, ,
SPAT
2.0
21.7
248
1308
O68.0
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly
2.5
21.0
133
548
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
1.9
20.9
279
1551
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
2.6
20.5
126
511
SPAT1380
SPAT
Postpartum check-up
2.3
20.0
165
765
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
4.3
19.8
52
125
O32.0
ICD-10 Finland
Maternal care for unstable lie
+∞
19.8
19
*
O99.5
ICD-10 Finland
Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
6.1
19.1
33
55
O34.1
ICD-10 Finland
Maternal care for tumour of corpus uteri
+∞
18.8
18
*
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
5.6
18.7
35
63
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
191.9
18.6
19
*
O66.5
ICD-10 Finland
Failed application of vacuum extractor and forceps, unspecified
16.4
18.3
29
18
O02.1
ICD-10 Finland
Missed abortion
2.1
18.2
179
891
A10AC01
ATC
insulin (human); parenteral
2.5
18.0
114
470
O62.0
ICD-10 Finland
Primary inadequate contractions
7.7
17.8
25
33
G03DA04
ATC
progesterone; systemic, rectal, vaginal
2.5
17.4
117
496
SPAT1189
SPAT
Other ultrasound examination during pregnancy
3.3
17.3
66
206
O28.1
ICD-10 Finland
Abnormal biochemical finding on antenatal screening of mother
5.5
17.2
33
61
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
5.6
17.0
32
58
O36.3
ICD-10 Finland
Maternal care for signs of fetal hypoxia
+∞
16.7
16
*
Z37.0
ICD-10 Finland
Single live birth
1.8
16.6
302
1843
ZXE00
NOMESCO Finland
One hour or less
1.5
16.3
663
4939
SPAT1200
SPAT
Guidance for breast-feeding and breast care
3.4
16.2
57
169
O83.8
ICD-10 Finland
Other specified assisted single delivery
12.3
15.9
28
23
MAB10
NOMESCO Finland
External version
60.6
15.8
18
*
O36.4
ICD-10 Finland
Maternal care for intrauterine death
+∞
15.6
15
*
O41.8
ICD-10 Finland
Other specified disorders of amniotic fluid and membranes
+∞
15.6
15
*
O24.1
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, non-insulin-dependent
5.8
14.9
27
47
MAW96
NOMESCO Finland
Other operation in pregnancy or at delivery
6.0
14.8
26
44
MA4AT
NOMESCO Finland
Chorion biopsy with ultrasound guidance
57.2
14.8
17
*
O44.0
ICD-10 Finland
Placenta praevia specified as without haemorrhage
+∞
14.6
14
*
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
5.2
14.6
30
59
O80.0
ICD-10 Finland
Spontaneous vertex delivery
0.7
14.5
517
6882
ZXH09, ,
SPAT
2.7
14.4
76
286
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
1.9
14.3
200
1125
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.0
14.1
168
894
J01CA08
ATC
pivmecillinam; oral
1.5
13.5
959
7894
Z36.9
ICD-10 Finland
Antenatal screening, unspecified
2.8
13.4
66
240
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
4.5
13.3
32
72
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
2.1
13.3
131
652
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
1.9
13.1
184
1036
MAE20
NOMESCO Finland
Failed vacuum delivery
14.1
12.8
21
15
6441A
ICD-9 Finland
Early or threatened labour, Other threatened labour
+∞
12.5
12
*
O65.0
ICD-10 Finland
Obstructed labour due to deformed pelvis
130.9
12.4
13
*
A10AB01
ATC
insulin (human); parenteral
2.6
12.4
74
297
6531A
ICD-9 Finland
Disproportion, Generally contracted pelvis[PELVIS ANGUSTA,RASKAUDEN AIKANA]
10.6
11.8
22
21
ZXD00
NOMESCO Finland
Emergency procedure
2.9
11.8
56
200
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
3.9
11.7
34
89
6620B
ICD-9 Finland
Long labour, Prolonged first stage
5.6
11.7
22
40
W78
ICPC
Pregnancy
1.6
11.6
263
1694
O35.2
ICD-10 Finland
Maternal care for (suspected) hereditary disease in fetus
+∞
11.5
11
*
O44.1
ICD-10 Finland
Placenta praevia with haemorrhage
120.8
11.4
12
*
O21.0
ICD-10 Finland
Mild hyperemesis gravidarum
3.8
11.2
33
87
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
2.4
11.2
80
349
O65.5
ICD-10 Finland
Obstructed labour due to abnormality of maternal pelvic organs
17.1
11.2
17
10
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
3.3
11.1
41
126
A10AB04
ATC
insulin lispro; parenteral
2.5
11.1
67
271
O68.1
ICD-10 Finland
Labour and delivery complicated by meconium in amniotic fluid
4.9
11.0
24
50
H04AA01
ATC
glucagon; nasal, parenteral
2.8
10.9
55
203
J01DB01
ATC
cefalexin; oral
1.5
10.7
1491
13603
NE1MA
NOMESCO Finland
Birth channel measurement with X-ray
60.4
10.6
12
*
G02CB01
ATC
bromocriptine; systemic
2.5
10.6
63
253
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
2.1
10.5
102
505
O34.0
ICD-10 Finland
Maternal care for congenital malformation of uterus
+∞
10.4
10
*
O46.8
ICD-10 Finland
Other antepartum haemorrhage
+∞
10.4
10
*
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.6
10.4
275
1838
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
2.9
10.3
47
164
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
2.4
10.2
67
282
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
2.2
10.2
88
417
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.6
10.0
276
1859
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
3.0
10.0
43
145
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
0.3
10.0
26
861
J01CA04
ATC
amoxicillin; systemic
1.5
9.8
1515
13938
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
2.6
9.7
53
204
Z12.4
ICD-10 Finland
Special screening examination for neoplasm of cervix
2.0
9.7
112
591
O82.9
ICD-10 Finland
Delivery by caesarean section, unspecified
55.3
9.7
11
*
WX290
NOMESCO Finland
Other blockage of nerve
1.4
9.6
992
8499
SFA20
NOMESCO Finland
Two-surface restoration
1.4
9.5
1164
10241
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
3.9
9.4
27
70
O34.8
ICD-10 Finland
Maternal care for other abnormalities of pelvic organs
+∞
9.4
9
*
O36.0
ICD-10 Finland
Maternal care for rhesus isoimmunization
+∞
9.4
9
*
O33.7
ICD-10 Finland
Maternal care for disproportion due to other fetal deformities
+∞
9.4
9
*
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
2.3
9.4
66
287
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
9.3
519
4018
A10AE05
ATC
insulin detemir; parenteral
2.2
9.2
73
334
MAA96
NOMESCO Finland
Other intrauterine operation on pregnant uterus or fetus
13.7
9.2
15
11
O68.3
ICD-10 Finland
Labour and delivery complicated by biochemical evidence of fetal stress
4.3
9.1
23
54
XMA00, ,
NOMESCO Finland
4.6
9.1
21
46
WX600
NOMESCO Finland
Single shot through catheter
2.8
9.0
43
154
6533A
ICD-9 Finland
Disproportion, Outlet contraction of pelvis[PELVIS ANGUSTA, ANOM APERT INFER,RASKAUDEN AIKANA]
15.7
9.0
14
9
W29
ICPC
Pregnancy symptom/complaint other
2.6
8.9
50
195
Z31.5
ICD-10 Finland
Genetic counselling
1.8
8.9
127
719
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.4
8.9
62
269
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
4.5
8.8
21
47
ZXH06, ,
SPAT
2.1
8.8
80
387
Z3232
NOMESCO Finland
Midwife
1.6
8.8
225
1490
LCA16
NOMESCO Finland
Destruction of endometrium
2.4
8.7
56
234
O62.1
ICD-10 Finland
Secondary uterine inertia
3.5
8.7
29
84
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
2.1
8.6
85
424
V252A
ICD-9 Finland
Contraceptive management, Sterilisation
0.1
8.6
*
275
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
2.5
8.6
52
211
Z35.1
ICD-10 Finland
Supervision of pregnancy with history of abortive outcome
8.3
8.6
18
22
6534A
ICD-9 Finland
Disproportion, Foetopelvic disproportion[DISPROPORTIO FOETOPELVICA,RASKAUDEN AIKANA]
11.6
8.6
15
13
65400
ICD-8 Finland
Occipital presentation
7.0
8.5
20
29
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
3.5
8.5
28
80
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.1
8.5
79
385
6601B
ICD-9 Finland
Obstructed labour, Obstruction by bony pelvis
10.1
8.5
16
16
SPAT1391
SPAT
Counselling and guidance related to family situation
3.8
8.5
25
66
W27
ICPC
Fear of complications of pregnancy
4.3
8.4
21
49
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
1.8
8.4
115
643
O64.8
ICD-10 Finland
Obstructed labour due to other malposition and malpresentation
4.9
8.4
18
37
O85
ICD-10 Finland
Puerperal sepsis
3.4
8.4
29
86
O34.3
ICD-10 Finland
Maternal care for cervical incompetence
+∞
8.3
8
*
6581A
ICD-9 Finland
Other problems associated with amniotic cavity and membranes, Premature rupture of membranes
+∞
8.3
8
*
R21
ICPC
Throat symptom/complaint
1.4
8.3
457
3518
O28.3
ICD-10 Finland
Abnormal ultrasonic finding on antenatal screening of mother
8.6
8.3
17
20
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
2.8
8.3
39
139
6532B
ICD-9 Finland
Disproportion, Inlet contraction of pelvis[PELVIS ANGUSTA, ANOM APERT SUPER,SYNNYTYKSEN AIKANA]
10.8
8.3
15
14
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
8.2
793
6667
A10AA01, ,
ATC
2.3
8.2
57
247
O10.0
ICD-10 Finland
Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
2.5
8.2
51
210
QBJ30
NOMESCO Finland
Correction of abdominal apron
3.1
8.1
33
108
O03.6
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, complicated by delayed or excessive haemorrhage
3.6
8.1
26
73
TLC02
NOMESCO Finland
Simple extraction of IUD
1.7
8.0
157
973
N02BE01
ATC
paracetamol; systemic, rectal
1.5
7.9
1568
14671
G02BA03
ATC
plastic IUD with progestogen
1.4
7.9
490
3847
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
7.7
551
4420
R3110
NOMESCO Finland
Psychosocial training
2.8
7.7
37
134
A10AA02, ,
ATC
2.3
7.6
55
242
O66.4
ICD-10 Finland
Failed trial of labour, unspecified
25.1
7.6
10
*
SPAT1263
SPAT
Sampling
1.3
7.6
621
5082
O81.4
ICD-10 Finland
Vacuum extractor delivery
1.6
7.5
154
967
SPAT1187
SPAT
General ultrasound examination in early pregnancy
3.9
7.4
21
54
O68.2
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly with meconium in amniotic fluid
3.6
7.4
24
68
O91.2
ICD-10 Finland
Nonpurulent mastitis associated with childbirth
3.3
7.4
27
83
6582B
ICD-9 Finland
Other problems associated with amniotic cavity and membranes, Delayed delivery after spontaneous or unspecified rupture of membranes
+∞
7.3
7
*
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
2.3
7.2
55
248
O26.9
ICD-10 Finland
Pregnancy-related condition, unspecified
4.3
7.2
18
42
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
7.2
1314
11987
E66.01
ICD-10 Finland
Obesity due to excess calories
1.5
7.2
244
1715
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
3.2
7.1
27
85
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
2.4
7.1
47
200
SPAT1192
SPAT
Gynaecological examination
1.5
6.8
242
1716
O66.2
ICD-10 Finland
Obstructed labour due to unusually large fetus
8.3
6.8
14
17
W30
ICPC
Pregnancy, Medical examin/health eval complete
5.7
6.8
18
32
ACC51
NOMESCO Finland
Release of median nerve
1.6
6.7
142
898
SPAT1262
SPAT
Handing over of treatment supplies
1.6
6.7
156
1011
G01AF05
ATC
econazole; vaginal
1.5
6.6
221
1547
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
6.6
243
1734
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
5.5
6.6
18
33
R09
ICPC
Sinus symptom/complaint
1.5
6.6
184
1242
W85
ICPC
Gestational diabetes
2.0
6.6
67
340
G03GB02
ATC
clomifene; oral
1.9
6.5
75
397
R51.80
ICD-10 Finland
Headache
1.4
6.5
319
2401
O00.1
ICD-10 Finland
Tubal pregnancy
2.2
6.5
53
247
SPAT1190
SPAT
Insertion or removal of intrauterine contraceptive device
1.6
6.5
164
1083
MAC00
NOMESCO Finland
Rupture of amniotic membrane
5.3
6.5
18
34
A10AB05
ATC
insulin aspart; parenteral
1.8
6.4
87
486
103
Kela drug reimbursment
Diabetes, insulin-treated
1.5
6.4
243
1746
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
3.8
6.4
19
51
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
2.4
6.3
40
167
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
0.5
6.3
42
902
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
2.7
6.3
31
114
SPAT1236
SPAT
Informing family of child’s disability
2.8
6.3
29
103
6584B
ICD-9 Finland
Other problems associated with amniotic cavity and membranes, Infection of amniotic cavity[AMNIONITIS, SYNNYTYKSEN AIKANA]
+∞
6.3
6
*
O45.9
ICD-10 Finland
Premature separation of placenta, unspecified
+∞
6.3
6
*
O32.4
ICD-10 Finland
Maternal care for high head at term
+∞
6.3
6
*
6450B
ICD-9 Finland
Prolonged pregnancy[GRAVIDITAS PROLANGATA CUM PARTU]
+∞
6.3
6
*
O41.9
ICD-10 Finland
Disorder of amniotic fluid and membranes, unspecified
+∞
6.3
6
*
O34.4
ICD-10 Finland
Maternal care for other abnormalities of cervix
+∞
6.3
6
*
O36.2
ICD-10 Finland
Maternal care for hydrops fetalis
+∞
6.3
6
*
O34.9
ICD-10 Finland
Maternal care for abnormality of pelvic organ, unspecified
+∞
6.3
6
*
O35.5
ICD-10 Finland
Maternal care for (suspected) damage to fetus by drugs
+∞
6.3
6
*
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
2.1
6.2
53
252
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.1
1116
10055
MWE00
NOMESCO Finland
Reoperation for deep haemorrhage in obstetric surgery
12.6
6.1
10
8
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
6.1
677
5735
SPAT1324
SPAT
Screening procedure
1.3
6.0
590
4914
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
6.0
1370
12688
SPAT1301
SPAT
No procedures
1.4
6.0
371
2895

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
495
3495
1.57
15.28
3.4
3.1
1.02
1.47
kg/l
0.50
312
2209
107
555
1.99
9.72
1.5
1.3
—
—
—
0
0
1084
9424
1.37
9.53
3.7
3.6
76.25
1325.91
e6/l
1.21
12
102
57
233
2.49
9.25
1.3
1.3
6.64
7.24
mmol/l
1.11
52
213
272
1913
1.50
8.03
1.8
1.7
—
—
—
0
0
85
453
1.92
7.20
7.6
7.1
—
—
—
0
0
456
3629
1.34
6.54
2.1
2.3
—
—
—
0
0
130
847
1.58
5.46
1.5
1.4
1103.58
1033.38
mu/l
0.41
108
642
43
200
2.18
5.34
2.1
1.8
5.02
5.66
umol/l
0.19
35
144
1628
15607
1.40
4.70
9.8
10.8
139.68
139.66
mmol/l
0.17
1602
15346
1633
15664
1.40
4.69
9.9
10.9
3.90
3.90
mmol/l
0.46
1604
15370
1746
16975
1.65
4.67
10.0
10.0
—
—
—
0
0
1635
15699
1.40
4.55
5.9
5.7
1.66
1.74
mu/l
2.22
1585
15259
511
4306
1.26
4.52
1.5
1.4
21.38
22.62
iu/ml
0.08
167
1291
728
6387
1.23
4.46
3.2
3.0
0.07
0.05
estimate
0.23
112
1290
534
4563
1.24
4.12
1.9
2.0
—
—
—
0
0
5
216
0.23
4.10
23.0
19.5
1366.20
5960.55
nmol/l
—
5
209
274
2161
1.32
4.05
2.7
2.9
50.71
370.09
ng/l
2.26
128
1080
5
211
0.23
3.96
14.2
14.2
771.80
6950.38
nmol/l
—
5
206
333
2712
1.28
3.86
2.2
2.5
8.24
8.64
e6/l
0.13
297
2458
407
3402
1.25
3.79
3.4
3.2
0.14
0.19
—
7
26
464
3940
1.24
3.74
1.4
1.3
7.48
8.44
u/ml
0.13
201
1784
1661
16071
1.37
3.67
10.7
11.5
18.36
18.04
mg/l
0.15
1362
12680
474
4045
1.23
3.64
2.5
2.9
54.01
89.42
e6/l
0.56
356
2998
384
4552
0.80
3.60
1.6
1.4
—
—
—
0
0
1091
10095
1.20
3.56
3.5
3.3
65.93
69.68
ug/l
0.58
1055
9789
91
1316
0.68
3.33
4.2
5.3
0.05
0.66
%
0.81
20
277
83
1221
0.66
3.32
1.5
1.4
—
—
—
0
0
761
6846
1.19
3.31
2.4
2.4
—
—
estimate
—
0
0
87
1264
0.67
3.27
3.8
4.9
0.62
0.76
%
0.21
26
324
400
3393
1.23
3.22
2.3
2.7
—
0.00
estimate
—
0
6
1744
17060
1.50
3.20
12.0
12.8
64.73
66.24
umol/l
2.83
1728
16913
1532
14719
1.25
3.14
5.1
4.6
38.00
37.19
mmol/mol
3.19
1498
14267
523
4588
1.20
2.95
2.2
2.6
55.14
56.44
u/l
0.30
503
4350
216
1723
1.29
2.95
1.5
1.7
—
—
—
0
0
737
6661
1.18
2.94
1.9
1.8
1.37
1.35
mmol/l
0.22
666
6019
90
1272
0.69
2.94
4.1
5.2
0.21
0.12
%
0.31
19
281
1808
17869
2.20
2.93
17.2
18.0
6.57
6.55
e9/l
0.09
1794
17625
726
6562
1.18
2.88
3.1
2.9
6.19
6.14
ph
0.64
471
3955
508
4459
1.19
2.84
2.1
2.5
14.93
25.30
ng/l
1.05
192
1770
1226
11572
1.18
2.81
6.5
7.6
71.50
73.39
u/l
1.14
1182
11165
11
33
3.35
2.81
1.1
1.7
—
0.18
—
0
5
405
3487
1.21
2.78
2.4
2.8
0.20
0.29
e6/l
1.21
290
2429
836
7663
1.17
2.75
3.5
4.1
6.52
6.29
mmol/l
1.83
777
7262
435
3775
1.20
2.75
1.9
2.1
161.22
139.24
u/l
0.23
420
3644
96
1323
0.71
2.73
4.1
5.1
1.12
0.93
%
0.32
25
334
1807
17867
2.09
2.73
17.3
18.2
40.16
41.91
%
2.32
1801
17774
392
3371
1.21
2.72
1.9
2.0
—
—
—
0
0
1474
14157
1.21
2.72
5.0
4.9
14.09
14.15
pmol/l
0.52
1434
13653
1680
16376
1.32
2.71
4.5
4.2
4.91
4.94
mmol/l
0.69
1651
15975
1807
17868
2.09
2.71
17.2
17.9
4.50
4.49
e12/l
0.72
1792
17634
1563
15105
1.24
2.69
4.0
4.0
5.69
5.61
mmol/l
1.55
1508
14564
259
2146
1.24
2.59
2.0
2.4
2.64
1.12
e6/l
0.37
135
1039
8
20
4.01
2.57
2.3
1.8
—
—
—
0
0
1745
17128
1.42
2.52
9.9
10.1
25.41
24.39
u/l
1.21
1730
16890
198
1596
1.27
2.51
1.1
1.2
—
—
—
0
0
529
4708
1.17
2.47
5.1
6.5
—
—
—
0
0
1674
16336
1.30
2.46
4.4
4.1
1.50
1.55
mmol/l
6.75
1641
15886
51
327
1.58
2.45
3.9
5.1
1.31
1.21
mmol/l
0.32
46
292
451
3964
1.18
2.45
1.7
1.7
0.70
0.67
mg/l
0.08
335
3043
17
76
2.25
2.44
1.3
1.1
—
—
—
0
0
1805
17860
1.93
2.39
17.2
18.0
274.21
276.13
e9/l
0.73
1796
17649
114
862
1.34
2.33
3.5
3.2
—
—
—
0
0
9
216
0.41
2.31
2.7
3.1
—
—
—
0
0
706
6452
1.15
2.30
5.1
6.1
1.22
1.22
mmol/l
0.16
638
5681
74
522
1.44
2.28
2.0
2.7
1.02
1.02
ratio
0.79
64
459
568
5112
1.16
2.27
2.9
3.4
59.07
55.60
e6/l
0.08
405
3378
15
66
2.28
2.24
1.3
1.2
600.00
1236.36
titre
—
5
11
883
8217
1.14
2.19
3.4
3.3
0.00
0.05
estimate
0.94
134
1536
370
3231
1.18
2.15
1.7
1.6
—
—
—
0
0
868
8080
1.14
2.12
3.4
3.2
0.01
0.00
estimate
0.28
135
1563
258
2184
1.21
2.12
1.7
1.6
—
—
—
0
0
52
760
0.67
2.10
1.8
1.4
0.29
0.42
nmol/l
1.22
46
596
86
634
1.37
2.09
1.1
1.1
3.14
4.60
eliau/ml
0.26
17
123
876
8165
1.14
2.09
3.4
3.2
10.09
3.79
estimate
0.27
140
1573
27
455
0.59
2.05
2.6
1.4
5.18
2.72
ug/l
0.44
21
390
70
963
0.72
2.03
3.0
3.3
1.23
1.23
mmol/l
0.04
64
855
615
5608
1.15
2.02
4.4
5.5
1.22
1.22
mmol/l
0.24
583
5312
41
263
1.57
2.01
1.2
1.1
15.00
1454.53
iu/ml
—
7
53
371
3259
1.17
2.01
3.5
3.3
12.86
39.41
mg/l
7.25
230
1911
19
97
1.97
2.00
1.6
1.7
132.26
129.73
nmol/l
0.11
19
97
356
3121
1.17
1.98
1.3
1.4
31.67
30.31
iu/l
0.30
327
2724
159
1291
1.25
1.94
1.1
1.1
—
—
—
0
0
153
1242
1.25
1.88
2.3
1.9
6.13
6.12
ph
0.02
102
695
8
28
2.87
1.86
4.0
2.2
—
—
—
0
0
132
1055
1.27
1.85
1.1
1.1
—
—
—
0
0
268
2310
1.19
1.82
2.2
2.6
536.63
512.99
mosm/kgh2o
0.86
230
2016
814
7597
1.13
1.82
5.3
5.9
9.70
9.38
umol/l
0.68
771
7263
370
3275
1.16
1.82
4.0
3.9
1.72
7.04
mg/mmol
10.02
230
1945
8
184
0.43
1.81
1.1
1.4
43.15
29.83
nmol/l
—
8
159
1678
16462
1.24
1.73
4.8
4.4
3.00
2.96
mmol/l
1.14
1640
15998
60
434
1.40
1.68
2.2
2.4
13.11
13.19
%
0.26
60
428
24
141
1.71
1.68
2.3
2.5
22.06
21.00
mg/l
0.05
16
98
7
25
2.81
1.65
2.4
1.8
—
—
—
0
0
32
206
1.56
1.60
1.0
1.0
1.33
0.39
u/ml
0.43
12
47
179
1507
1.21
1.59
4.4
5.8
1.07
1.03
mmol/l
1.46
168
1423
6
20
3.01
1.58
1.5
1.2
5.38
5.86
mmol/l
—
6
20
435
3939
1.14
1.55
3.3
3.2
8.11
7.71
mmol/l
0.99
392
3498
310
2742
1.16
1.55
2.7
4.0
—
—
—
0
0
445
4045
1.13
1.49
3.7
3.4
0.02
0.01
estimate
0.21
129
1502
314
2790
1.15
1.48
1.5
1.6
28522754.10
38692307.18
pmol/l
0.13
291
2538
60
798
0.74
1.47
1.3
1.4
32.84
29.50
u/l
0.35
49
660
28
427
0.65
1.47
1.3
1.3
345.77
317.28
ug/g
0.23
13
212
10
202
0.49
1.45
1.0
1.4
—
—
—
0
0
1472
14332
1.14
1.43
12.8
14.0
13.31
13.37
%
1.04
1457
14182
96
766
1.27
1.42
1.3
1.3
—
—
—
0
0
28
181
1.56
1.40
2.4
2.5
7.62
120.00
ug/min
2.67
16
122
6
137
0.44
1.40
2.3
3.4
2.52
3.14
nmol/l
—
6
128
11
53
2.08
1.38
1.0
1.0
—
—
—
0
0
11
53
2.08
1.38
1.0
1.0
—
—
—
0
0
11
53
2.08
1.38
1.0
1.0
—
—
—
0
0
9
41
2.20
1.37
1.0
1.3
—
—
—
0
0
10
197
0.50
1.36
1.5
2.4
17.49
16.87
%
—
10
192
1585
15523
1.16
1.36
3.8
3.6
1.23
1.21
mmol/l
0.62
1548
15040
109
889
1.24
1.35
2.1
3.6
1.96
1.75
mmol/l
0.20
88
774
227
1984
1.16
1.34
2.0
2.5
4.47
4.72
e6/l
0.11
106
882
9
42
2.15
1.33
1.4
1.5
—
—
—
0
0
10
195
0.51
1.33
1.3
2.8
91.70
91.71
%
—
10
189
12
61
1.97
1.33
2.0
2.5
—
—
—
0
0
29
192
1.52
1.32
1.6
2.5
51.69
64.02
%
2.49
29
192
7
150
0.46
1.31
1.4
3.2
—
—
—
0
0
29
194
1.50
1.27
1.0
1.0
0.48
0.19
u/ml
—
9
39
521
4827
1.11
1.25
1.4
1.3
1.16
1.55
u/ml
0.78
157
1433
283
2532
1.14
1.22
2.2
2.4
2.39
2.41
mmol/l
2.98
250
2302
90
1104
0.81
1.21
1.6
1.7
—
—
—
0
0
158
1357
1.18
1.18
1.3
1.3
25.22
41.68
au/ml
1.82
15
78
426
3919
1.11
1.16
3.5
3.9
7.40
7.40
ph
0.12
285
2711
115
963
1.21
1.14
1.9
2.3
0.10
0.33
e6/l
2.13
104
899
21
318
0.66
1.12
3.1
3.6
3.80
3.94
e9/l
0.15
21
318
23
151
1.53
1.11
1.0
1.0
—
—
—
0
0
674
7130
0.91
1.11
7.5
9.5
0.00
0.00
e9/l
0.83
531
5826
529
4934
1.10
1.10
2.4
2.5
0.11
0.04
—
9
67
209
1846
1.15
1.10
3.1
2.5
4.67
5.76
umol/l
1.73
183
1575
41
547
0.74
1.09
6.2
10.1
23.44
24.16
mmol/l
1.14
41
540
643
6059
1.09
1.08
4.5
4.6
37.67
37.38
g/l
0.89
619
5789
192
1690
1.15
1.07
1.7
1.7
1185.80
1192.35
nmol/l
0.04
169
1381
541
5064
1.10
1.04
3.1
3.5
2.33
2.34
mmol/l
2.25
507
4781
60
473
1.28
1.04
1.7
1.7
—
—
—
0
0
167
1462
1.16
1.01
2.3
2.3
24.11
25.02
au/ml
0.04
20
217
9
49
1.84
0.98
1.4
1.7
—
—
—
0
0
9
158
0.57
0.98
1.2
1.7
12.18
24.45
umol/l
—
9
148
109
924
1.19
0.98
2.2
3.5
7.38
7.38
ph
0.15
56
511
404
3745
1.10
0.96
1.9
2.1
287.84
293.45
umol/l
0.80
372
3490
429
4605
0.91
0.95
3.4
4.2
—
—
—
0
0
13
77
1.69
0.95
1.2
1.2
137.85
257.51
u/l
1.08
13
67
34
251
1.36
0.94
4.5
3.2
18.16
19.77
mg/l
0.17
24
172
17
109
1.56
0.93
4.4
2.5
13.60
13.41
index
—
10
74
60
481
1.26
0.93
3.8
4.5
—
—
—
0
0
8
145
0.55
0.93
1.1
1.2
—
—
—
0
0
53
664
0.79
0.91
2.6
2.0
0.19
0.02
estimate
0.56
21
250
13
78
1.67
0.91
1.9
4.3
—
—
—
0
0
6
28
2.15
0.91
1.2
1.3
34.97
36.54
%
—
6
22
422
3934
1.09
0.89
2.2
2.3
2.32
2.59
mg/l
2.78
376
3481
97
1138
0.84
0.88
1.2
1.2
—
—
—
0
0
67
548
1.23
0.88
1.0
1.1
2.92
4.40
u/ml
0.48
32
275
7
127
0.55
0.88
1.3
1.9
—
—
—
0
0
47
594
0.79
0.88
2.1
2.9
7.42
7.41
ph
0.14
39
492
8
43
1.86
0.87
5.4
2.5
0.60
0.62
mmol/l
—
8
43
31
229
1.36
0.87
1.3
1.3
—
—
—
0
0
96
1124
0.85
0.86
3.0
3.3
—
—
—
0
0
12
191
0.63
0.84
2.4
2.8
1.70
2.26
mmol/l
—
5
130
12
73
1.65
0.81
2.9
3.4
210.17
192.49
umol/l
—
6
41
76
637
1.20
0.81
1.1
1.1
1.80
2.04
u/ml
0.08
40
307
159
1414
1.14
0.80
1.2
1.2
—
—
—
0
0
0
24
0.00
0.79
0.0
1.2
—
316.38
—
0
5
8
48
1.67
0.78
5.1
4.7
—
—
—
0
0
63
521
1.22
0.77
1.0
1.1
1.17
0.81
u/ml
0.40
26
209
26
348
0.74
0.76
1.2
1.2
—
—
—
0
0
28
209
1.35
0.75
1.0
1.1
0.40
0.38
u/ml
0.05
12
63
15
220
0.68
0.74
1.0
1.4
—
—
—
0
0
616
5875
1.07
0.74
1.9
1.9
99.98
100.84
pmol/l
0.18
338
3273
13
196
0.66
0.74
1.1
1.1
—
—
—
0
0
31
402
0.77
0.74
2.5
3.6
56.55
57.90
%
0.39
31
402
263
2851
0.91
0.74
2.5
2.5
99.43
96.23
ug/g
0.05
219
2262
146
1301
1.13
0.73
2.2
1.9
3757.17
3308.38
u/l
0.08
48
428
22
159
1.39
0.72
2.3
2.4
4.74
5.43
u/ml
0.16
22
159
19
134
1.42
0.71
1.2
1.1
451.47
421.88
nmol/l
0.26
19
128
49
598
0.81
0.71
1.3
1.3
62.55
31.06
u/ml
—
6
54
16
227
0.70
0.68
1.1
1.1
23.80
16.79
u/ml
—
10
106
336
3142
1.09
0.68
1.4
1.4
518.79
521.94
titre
0.01
66
661
627
6007
1.07
0.65
3.6
3.2
28.06
27.90
u/l
0.04
605
5752
785
8127
0.94
0.65
5.6
6.6
29.57
29.74
%
0.20
743
7809
96
1094
0.87
0.65
4.1
3.9
2.81
43.86
ug/l
0.65
70
778
65
551
1.19
0.65
1.5
1.3
65.11
63.94
ug/l
0.05
49
418
256
2373
1.09
0.64
2.0
2.5
14.36
14.68
umol/l
0.34
248
2259
8
130
0.61
0.63
1.5
1.9
—
—
—
0
0
13
87
1.50
0.63
1.8
1.7
3.86
2.53
u/field
—
7
51
10
63
1.59
0.61
1.4
2.5
—
—
—
0
0
30
235
1.28
0.61
1.6
2.6
51.80
65.63
%
3.02
30
228
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
136
1226
1.12
0.59
2.0
1.9
0.17
0.04
estimate
0.46
23
305
110
1232
0.89
0.59
3.1
2.3
0.22
0.23
g/l
1.25
104
1180
7
112
0.62
0.58
8.3
8.2
14.17
11.43
mg/l
—
7
106
8
54
1.48
0.57
1.1
1.5
—
—
—
0
0
16
115
1.39
0.56
1.0
1.0
—
—
—
0
0
31
385
0.80
0.56
1.4
1.2
186.57
267.19
u/ml
1.89
21
258
8
55
1.46
0.56
1.0
1.2
—
—
—
0
0
104
1164
0.89
0.56
1.5
1.7
315.85
331.18
mu/l
0.09
95
1042
27
340
0.79
0.55
2.4
2.0
5.16
5.50
mmol/24h
0.25
27
321
207
1918
1.09
0.54
1.3
1.5
—
—
—
0
0
358
3390
1.07
0.54
1.6
1.6
20.82
20.40
nmol/l
0.24
334
3105
11
158
0.69
0.52
1.2
1.1
—
—
—
0
0
10
66
1.52
0.52
1.1
1.1
—
—
—
0
0
48
565
0.85
0.52
6.0
10.7
0.77
0.67
%
0.81
48
560
9
132
0.68
0.52
1.1
1.1
—
—
—
0
0
6
40
1.50
0.51
1.0
1.2
—
—
—
0
0
6
40
1.50
0.51
1.0
1.0
—
—
—
0
0
9
64
1.41
0.51
1.4
1.8
—
—
—
0
0
778
8012
0.95
0.51
5.5
6.4
56.54
56.38
%
0.18
736
7739
836
8593
0.95
0.51
5.6
6.6
0.51
0.52
e9/l
0.72
734
7697
60
692
0.86
0.51
1.3
1.2
—
—
—
0
0
837
8602
0.95
0.51
5.7
6.6
0.04
0.04
e9/l
0.47
732
7692
160
1737
0.91
0.50
1.3
1.4
—
—
—
0
0
11
156
0.70
0.50
1.0
1.1
124.36
120.37
pmol/l
0.09
11
156
10
144
0.69
0.49
1.8
1.3
8.94
9.73
umol/l
—
10
133
808
7856
1.05
0.49
2.7
2.5
74.96
74.66
nmol/l
0.11
770
7521
516
4960
1.06
0.48
2.6
2.6
0.03
0.04
estimate
0.18
103
1283
14
189
0.74
0.48
3.2
4.2
21.79
42.48
u/ml
0.61
14
189
14
102
1.38
0.47
1.1
1.1
—
—
—
0
0
762
7836
0.95
0.47
5.7
6.7
0.66
0.70
%
2.03
710
7433
114
1037
1.11
0.46
3.6
3.5
7.27
7.36
ph
1.25
78
753
63
716
0.88
0.45
1.9
2.8
75.46
72.29
e9/l
0.24
45
514
7
51
1.37
0.44
1.0
1.2
0.09
0.04
u/ml
—
7
51
870
8908
0.96
0.44
5.7
7.0
0.19
0.18
e9/l
0.43
798
8093
16
207
0.77
0.42
1.0
1.5
—
—
—
0
0
118
1081
1.10
0.42
1.4
1.4
217.69
221.96
miu/ml
0.04
52
566
6
92
0.65
0.42
2.8
3.6
—
—
—
0
0
120
1101
1.10
0.42
1.2
1.1
47.00
126.73
titre
—
5
37
764
7839
0.96
0.42
5.7
6.7
7.95
8.16
%
1.85
716
7482
60
529
1.14
0.41
2.3
3.9
24.12
24.29
mmol/l
0.17
60
524
190
2027
0.93
0.41
1.2
1.3
135.71
148.49
u/ml
0.22
86
863
20
250
0.80
0.41
1.3
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
0.10
—
0
5
0
15
0.00
0.41
0.0
1.5
—
38.37
—
0
15
0
15
0.00
0.41
0.0
2.1
—
7.34
—
0
15
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
2.8
—
—
—
0
0
0
16
0.00
0.41
0.0
4.1
—
5.11
—
0
16
0
16
0.00
0.41
0.0
1.4
—
422.31
—
0
16
43
370
1.17
0.41
3.6
2.4
1.76
1.80
index
0.02
21
197
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
42
361
1.17
0.40
1.0
1.0
—
—
—
0
0
10
138
0.72
0.40
2.4
1.4
1.05
0.91
promille
—
10
108
227
2143
1.07
0.40
1.9
2.4
2.48
2.49
g/l
0.12
212
2016
7
103
0.68
0.39
1.0
1.8
-0.39
0.76
mmol/l
—
7
98
0
19
0.00
0.39
0.0
2.2
—
6.42
—
0
19
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
764
7824
0.96
0.38
5.6
6.6
2.72
2.77
%
0.27
714
7455
862
8803
0.96
0.37
5.6
6.6
1.97
1.98
e9/l
0.13
789
8030
61
544
1.13
0.37
1.1
1.1
2.30
1.09
u/ml
0.71
32
247
52
460
1.13
0.36
1.1
1.1
5.45
3.15
u/ml
0.58
25
184
6
43
1.40
0.35
1.0
1.2
—
—
—
0
0
19
154
1.24
0.34
1.2
1.2
0.60
0.60
ratio
0.01
12
87
28
329
0.85
0.33
1.1
1.2
6.00
2.69
u/ml
0.56
15
137
13
100
1.30
0.33
1.6
1.8
48.38
37.19
%
0.60
13
52
740
7566
0.96
0.33
2.1
2.0
—
—
—
0
0
6
46
1.31
0.33
1.3
1.3
—
—
—
0
0
435
4210
1.04
0.32
1.9
1.9
—
—
—
0
0
105
973
1.08
0.32
1.4
1.8
—
—
—
0
0
317
3297
0.95
0.32
1.8
1.8
3.38
3.31
ratio
0.40
222
2374
35
304
1.15
0.32
1.2
1.1
—
—
—
0
0
7
54
1.30
0.30
1.4
1.6
—
—
—
0
0
25
212
1.18
0.30
1.2
1.5
—
—
—
0
0
8
106
0.75
0.29
3.3
2.7
—
—
—
0
0
20
238
0.84
0.28
1.8
2.2
—
—
—
0
0
87
938
0.92
0.28
1.2
1.4
0.40
1.58
u/ml
1.37
13
76
23
269
0.85
0.27
4.4
5.2
30.76
138.61
u/ml
1.20
11
87
11
139
0.79
0.27
1.0
1.2
7.45
9.38
mm/h
0.56
11
139
170
1617
1.06
0.26
2.6
2.5
26.40
35.53
u/ml
1.37
165
1569
143
1510
0.94
0.26
2.6
2.4
32.46
41.32
u/l
1.23
125
1288
58
529
1.10
0.26
1.2
1.3
100.00
105.50
titre
—
7
60
855
8689
0.97
0.26
2.5
2.5
—
—
—
0
0
5
72
0.69
0.26
1.0
1.2
34.60
28.69
s
—
5
72
35
394
0.89
0.26
2.4
2.8
—
—
—
0
0
236
2456
0.96
0.26
1.7
1.6
—
—
—
0
0
114
1072
1.07
0.26
1.4
1.8
—
—
—
0
0
17
202
0.84
0.24
1.6
1.7
—
—
—
0
0
13
159
0.82
0.24
13.6
13.8
0.56
0.64
mmol/l
0.89
13
143
23
198
1.16
0.24
1.3
1.2
—
—
—
0
0
110
1167
0.94
0.24
1.1
1.1
0.52
0.63
ratio
—
9
121
11
87
1.27
0.24
1.3
1.4
595.00
73654.23
e6/l
—
6
66
30
339
0.88
0.24
1.9
1.7
359.20
396.30
mu/l
0.18
25
282
114
1077
1.06
0.23
1.4
1.8
—
—
—
0
0
52
476
1.10
0.23
1.4
1.3
—
—
—
0
0
137
1440
0.95
0.23
3.9
3.6
31.52
32.07
%
0.26
110
1134
115
1215
0.94
0.23
1.1
1.1
1.58
1.62
g/l
0.94
115
1215
21
181
1.16
0.22
1.2
1.5
—
—
—
0
0
39
352
1.11
0.22
2.1
2.6
6.15
6.74
pmol/l
0.32
39
352
51
468
1.09
0.22
1.4
1.3
1.18
1.23
mm
0.35
32
315
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
339.60
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
18
154
1.17
0.21
1.1
1.1
—
—
—
0
0
428
4181
1.03
0.21
1.4
1.5
2.13
2.11
g/l
0.13
288
2890
202
1946
1.04
0.21
1.6
1.8
—
—
—
0
0
53
574
0.92
0.21
1.1
1.1
—
—
—
0
0
86
809
1.07
0.21
1.5
1.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
0.17
—
0
13
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
114
1083
1.06
0.20
1.4
1.8
—
—
—
0
0
73
779
0.93
0.20
1.7
1.7
0.25
0.30
mg/l
0.41
32
338
0
14
0.00
0.20
0.0
3.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.8
—
73.11
—
0
9
48
521
0.92
0.20
1.1
1.3
—
—
—
0
0
113
1075
1.05
0.19
1.4
1.6
—
—
—
0
0
24
270
0.89
0.19
2.5
3.9
1.30
1.29
mmol/l
0.01
24
263
25
223
1.12
0.18
1.0
1.1
—
—
—
0
0
51
548
0.93
0.17
1.1
1.2
—
—
—
0
0
7
61
1.15
0.17
1.1
1.1
4.97
8.12
u/ml
—
7
61
81
855
0.94
0.17
1.7
1.7
12.84
11.97
u/ml
0.08
24
288
13
110
1.18
0.17
1.0
1.1
—
6.53
—
0
21
102
1069
0.95
0.17
1.5
2.0
1.35
1.35
g/l
0.02
97
1010
307
2997
1.03
0.16
1.4
1.3
—
—
—
0
0
68
641
1.06
0.16
2.4
2.1
—
—
—
0
0
222
2156
1.03
0.16
2.7
3.5
0.82
0.83
mmol/l
0.51
210
2070
11
92
1.20
0.16
1.2
1.9
1.24
1.20
mmol/l
1.09
11
92
6
76
0.79
0.15
1.5
1.9
67.00
85.26
ng/l
—
6
76
198
1922
1.03
0.15
2.0
2.5
23.71
23.75
%
0.02
192
1811
89
931
0.95
0.14
1.6
2.3
2.62
7.27
iu/ml
2.08
24
244
33
304
1.09
0.14
1.0
1.2
—
—
—
0
0
16
181
0.88
0.14
1.4
1.2
—
—
—
0
0
20
179
1.12
0.14
1.2
1.2
0.16
0.26
nmol/l
0.40
14
122
24
264
0.91
0.14
1.9
2.5
—
—
—
0
0
18
160
1.13
0.14
1.1
1.1
—
—
—
0
0
53
500
1.06
0.13
1.1
1.1
7.37
2.53
u/ml
0.56
22
223
223
2176
1.03
0.13
1.2
1.2
—
—
—
0
0
46
432
1.07
0.13
1.8
2.3
—
—
—
0
0
62
652
0.95
0.13
1.4
1.4
2.57
11.17
u/ml
—
7
104
20
181
1.11
0.12
1.2
1.5
—
—
—
0
0
15
133
1.13
0.12
2.8
1.3
—
—
—
0
0
53
503
1.06
0.11
1.5
1.4
—
—
—
0
0
159
1632
0.97
0.11
1.5
1.5
—
—
—
0
0
178
1820
0.98
0.10
2.2
2.2
365.18
368.05
nmol/l
0.09
169
1703
381
3760
1.02
0.09
4.0
3.5
99.83
99.53
%
0.10
373
3665
11
97
1.13
0.09
1.2
1.9
107.18
105.49
mmol/l
0.65
11
97
11
97
1.13
0.09
1.2
1.9
4.04
3.87
mmol/l
1.54
11
97
17
185
0.92
0.08
1.1
1.2
0.17
1.45
u/ml
1.03
11
107
78
805
0.97
0.08
4.8
9.3
—
—
—
0
0
67
647
1.04
0.08
1.1
1.2
—
—
—
0
0
7
64
1.09
0.08
1.0
1.1
—
—
—
0
0
7
65
1.08
0.08
1.3
1.1
—
—
—
0
0
18
194
0.93
0.07
1.4
1.2
—
—
—
0
0
44
422
1.04
0.07
1.0
1.1
0.42
0.35
u/ml
0.07
13
117
32
304
1.05
0.07
1.3
1.1
—
—
—
0
0
327
3307
0.99
0.07
1.5
1.5
—
—
—
0
0
44
458
0.96
0.07
1.2
1.1
—
—
—
0
0
10
89
1.12
0.07
2.4
3.0
9.24
113.61
mg/l
—
5
58
8
93
0.86
0.06
2.3
1.7
—
—
—
0
0
29
275
1.06
0.06
1.6
1.7
5512.00
5685.50
e6/l
0.03
22
200
43
413
1.04
0.06
1.0
1.1
1.38
2.79
eliau/ml
1.80
24
244
229
2321
0.98
0.06
1.2
1.2
—
—
—
0
0
134
1365
0.98
0.06
2.3
2.9
10.26
10.64
g/l
0.83
128
1278
41
394
1.04
0.06
1.1
1.4
—
—
—
0
0
12
109
1.10
0.06
1.1
1.1
1846.00
1542.82
miu/ml
0.39
12
109
40
416
0.96
0.06
1.4
1.4
16596.94
729.40
e6/l
0.49
32
326
102
1041
0.98
0.05
5.0
8.0
0.50
0.79
mmol/l
0.41
77
825
19
178
1.07
0.05
1.2
1.2
—
—
—
0
0
39
405
0.96
0.05
1.4
1.4
25.19
21.26
e6/l
0.08
31
300
13
141
0.92
0.05
4.3
3.4
454.15
680.65
u/ml
0.97
13
141
14
151
0.93
0.05
1.7
1.7
0.21
2.17
u/ml
—
5
43
31
297
1.04
0.05
2.7
3.6
0.94
0.89
nmol/l
0.20
26
269
221
2233
0.99
0.04
3.0
3.1
3.97
4.35
e9/l
1.01
201
2031
162
1600
1.01
0.04
3.7
3.6
4.53
4.51
pmol/l
0.07
145
1454
10
91
1.10
0.04
1.0
1.2
—
—
—
0
0
949
9461
1.01
0.04
8.1
10.2
4.12
3.94
e9/l
1.25
838
8415
30
311
0.96
0.03
1.1
1.4
—
55.37
—
0
26
22
210
1.05
0.03
2.2
3.4
—
—
—
0
0
71
697
1.02
0.03
2.3
1.9
—
—
—
0
0
56
548
1.02
0.03
1.1
1.1
—
—
—
0
0
58
592
0.98
0.03
1.4
1.9
3.44
5.81
ug/l
1.39
44
521
19
181
1.05
0.03
1.2
1.5
—
—
—
0
0
19
181
1.05
0.03
1.2
1.5
—
—
—
0
0
46
471
0.98
0.03
1.3
1.3
534.72
446.36
mg/l
0.32
46
453
33
320
1.03
0.03
1.8
1.4
143.29
159.77
au/ml
—
7
84
36
350
1.03
0.03
3.8
3.6
217.71
451.92
mg/l
0.71
14
149
56
549
1.02
0.03
1.1
1.1
—
—
—
0
0
104
1052
0.99
0.02
5.0
8.2
7.42
7.42
ph
0.01
61
596
16
152
1.05
0.02
1.3
1.6
51.11
67.70
mmol/l
—
9
119
16
152
1.05
0.02
1.1
1.0
271.25
305.67
mg/l
0.97
16
137
96
971
0.99
0.02
3.0
3.6
76.16
75.49
ng/l
0.02
88
881
22
212
1.04
0.02
6.5
2.6
37.95
32.33
umol/l
0.48
22
202
75
740
1.01
0.02
1.9
2.3
—
—
—
0
0
47
479
0.98
0.02
1.2
1.2
—
—
—
0
0
1304
13025
1.00
0.02
3.1
3.1
32.84
33.98
u/l
0.32
1273
12685
496
4974
1.00
0.02
5.0
6.5
1.05
1.06
inr
0.23
405
4056
45
458
0.98
0.01
1.0
1.1
10.32
11.47
au/ml
—
6
147
253
2541
0.99
0.01
1.5
1.6
3.48
3.54
mmol/l
0.37
157
1655
63
638
0.99
0.01
2.5
2.2
3.08
3.86
iu/l
0.68
28
312
181
1801
1.01
0.01
1.7
2.0
—
—
—
0
0
106
1068
0.99
0.01
2.0
2.5
1.74
1.72
%
0.07
94
957
41
403
1.02
0.01
1.2
1.2
—
—
—
0
0
61
617
0.99
0.01
1.5
2.0
21.00
20.07
s
0.57
49
520
10
94
1.06
0.01
1.0
1.1
—
—
—
0
0
160
1594
1.00
0.00
1.3
1.3
140.60
215.30
u/ml
0.52
155
1478
63
625
1.01
0.00
1.3
1.3
—
—
—
0
0
11
106
1.04
0.00
1.6
1.2
70.91
65.69
umol/l
0.21
11
106
21
214
0.98
0.00
2.3
2.0
—
—
—
0
0
223
2226
1.00
0.00
2.1
2.6
527.23
410.30
ng/l
0.17
176
1796
34
342
0.99
0.00
1.8
1.7
1.20
1.39
g/l
0.62
27
297
34
337
1.01
0.00
1.7
1.3
—
—
—
0
0
9
98
0.92
0.00
1.1
1.3
122.89
155.22
mmol/24h
—
9
98
0
6
0.00
0.00
0.0
1.2
—
208.01
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
75.50
—
0
6
7
77
0.91
-0.00
46.3
38.3
7.90
7.20
ug/l
—
7
69
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
190.00
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.6
—
490.20
—
0
5
5
55
0.91
-0.00
1.0
1.0
—
—
—
0
0
5
58
0.86
-0.00
1.2
1.4
18.80
34.11
mmol/l
—
5
51
0
9
0.00
-0.00
0.0
2.6
—
40.33
—
0
9
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
22
220
1.00
-0.00
1.5
1.6
17.19
27.62
ng/l
1.59
22
220
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
45.63
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
50.54
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
108.40
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
259.60
—
0
5

Mortality – FinRegistry

Association

Association between endpoint O15_MATERN_CARE_DISPROP and mortality.

Females

Parameter HR [95% CI] p-value
O15_MATERN_CARE_DISPROP 0.535 [0.43, 0.67] < 0.001
Birth year 0.993 [0.98, 1.0] 0.104

During the follow-up period (1.1.1998 — 31.12.2019), 89 out of 11794 females with O15_MATERN_CARE_DISPROP died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_MATERN_CARE_DISPROP.

N-year risk Females Males
1 0.059% No data
5 0.321% No data
10 0.697% No data
15 1.412% No data
20 2.428% No data

Relationships between endpoints

Index endpoint: O15_MATERN_CARE_DISPROP – Maternal care for known or suspected disproportion

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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