info icon

Use of rotigotine

PDMED_ROTIGOTINE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC N04BC09

1 out of 7 registries used, show all original rules.

433

4. Check minimum number of events

Min. number of events 3
433

5. Include endpoints

None

433

6. Filter based on genotype QC (FinnGen only)

395

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 395 225 170
Unadjusted period prevalence (%) 0.08 0.08 0.08
Median age at first event (years) 64.86 64.66 65.12

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
407
Matched controls
4070
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N04BC05
ATC
pramipexole; oral
46.9
307.7
283
189
G20
ICD-10 Finland
Parkinson disease
273.5
307.7
320
54
N04BD01
ATC
selegiline; oral
232.7
307.7
236
24
N04BA03
ATC
levodopa, decarboxylase inhibitor and COMT inhibitor; oral
305.8
307.7
209
14
193
Kela drug reimbursment
Rasagiline
252.3
307.7
156
10
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
278.5
307.7
336
68
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
298.5
307.7
322
51
N87
ICPC
Parkinsonism
145.2
307.7
184
23
N04BD02
ATC
rasagiline; oral
302.0
307.7
192
12
N04BC04
ATC
ropinirole; oral
370.8
307.7
221
13
N04BC09
ATC
rotigotine; transdermal
+∞
307.7
407
*
N03AE01
ATC
clonazepam; systemic
14.5
117.1
122
117
N04BB01
ATC
amantadine; oral
42.0
104.0
64
18
G25.9
ICD-10 Finland
Extrapyramidal and movement disorder, unspecified
40.6
80.9
50
14
N06DA03
ATC
rivastigmine; oral, transdermal
10.6
71.1
87
102
R25.1
ICD-10 Finland
Tremor, unspecified
13.4
65.4
66
58
N05AH04
ATC
quetiapine; oral
5.8
63.7
162
414
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
12.5
62.6
66
62
AAG20
NOMESCO Finland
Stereotactic intracranial implantation of electrodes
112.2
62.0
66
7
N04BX02
ATC
entacapone; oral
220.2
56.6
57
*
N04AA02
ATC
biperiden; systemic
16.2
55.4
49
34
F02.39*G20
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
84.1
52.6
58
8
N04BX04
ATC
opicapone; oral
180.8
46.9
48
*
XA800
NOMESCO Finland
Neuropsychological investigation
9.3
45.6
59
73
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
10.8
43.0
49
51
AEA50
NOMESCO Finland
Adjustment of implanted neurostimulator
85.9
41.9
46
6
G04BD12
ATC
mirabegron; oral
4.5
40.4
128
376
AA1AD
NOMESCO Finland
CT of head and brain
3.7
37.6
210
909
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.2
35.7
125
392
N03AX12
ATC
[U] gabapentin; oral
3.9
35.5
141
483
SPAT1229
SPAT
Assessment of need for aid
5.1
33.3
79
182
L28
ICPC
Limited function/disability (L)
3.6
32.5
150
564
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
5.3
31.2
70
153
A28
ICPC
Limited function/disability NOS
3.6
30.6
138
509
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
33.7
28.7
37
12
R4130
NOMESCO Finland
Speech therapy
8.6
28.6
38
48
N06AX11
ATC
mirtazapine; oral
3.1
27.9
207
1018
SPAT1231
SPAT
Assessment of adjustments needed in living environment
10.4
27.1
31
32
N19
ICPC
Speech disorder
27.2
25.7
35
14
SPAT1215
SPAT
Assessment of need for medical rehabilitation
6.7
25.6
43
71
K59.09
ICD-10 Finland
Constipation, unspecified
4.4
24.0
68
179
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.9
23.8
82
249
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.5
23.6
63
158
R1250
NOMESCO Finland
Evaluation of functional capability
7.5
22.8
34
49
C07AA05
ATC
propranolol; systemic
3.1
22.8
129
534
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
4.2
20.8
61
164
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.0
20.7
123
519
R53
ICD-10 Finland
Malaise and fatigue
2.8
20.7
154
733
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.7
20.6
177
906
N28
ICPC
Limited function/disability (N)
8.9
20.4
26
31
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.0
19.7
111
454
ZXM20
NOMESCO Finland
Intraoperative use of computerised tomography
15.9
19.2
31
21
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.7
18.6
66
203
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
3.8
18.5
62
183
N03AX16
ATC
[U] pregabalin
2.6
18.1
143
693
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.8
17.3
57
166
SPAT1216
SPAT
Assessment of functional ability
2.8
17.1
103
433
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.4
16.7
176
971
N05BA04
ATC
oxazepam; oral
2.5
16.5
145
734
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.8
16.1
97
407
U04
ICPC
Incontinence urine
3.8
15.7
52
152
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
4.0
15.6
47
128
I95.1
ICD-10 Finland
Orthostatic hypotension
4.8
15.0
35
78
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
6.0
14.8
27
48
R47.1
ICD-10 Finland
Dysarthria and anarthria
14.9
14.7
24
17
N06AX21
ATC
duloxetine; oral
3.0
14.6
74
282
H02AA02
ATC
fludrocortisone; oral
17.8
14.5
22
13
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
12.6
14.3
25
21
N02AA05
ATC
oxycodone; systemic
2.5
14.1
115
558
M03BX01
ATC
baclofen; systemic
6.5
13.9
23
37
A06AD11
ATC
lactulose; oral
2.7
13.7
86
367
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
+∞
13.6
13
*
N04BC07
ATC
apomorphine; parenteral
+∞
13.6
13
*
N06AX16
ATC
venlafaxine; oral
2.7
13.6
84
355
R35
ICD-10 Finland
Polyuria
3.3
13.2
53
175
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
4.4
13.0
34
83
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.2
12.9
57
200
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
3.6
12.9
45
136
YX8AD
NOMESCO Finland
Stereotactic CT examination for dose design of radiotherapy
72.2
12.7
14
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.8
12.4
69
275
A04
ICPC
Weakness/tiredness general
2.6
12.4
85
377
SPAT1234
SPAT
Support of social functional capacity
3.9
12.2
37
101
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
5.6
12.0
23
43
R13
ICD-10 Finland
Dysphagia
3.1
12.0
53
186
D21
ICPC
Swallowing problem
9.4
11.9
24
27
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.5
11.7
87
400
Z2445
NOMESCO Finland
Psychologist
4.6
11.6
28
64
R5110, ,
SPAT
2.8
11.4
61
238
N29
ICPC
Neurological sympt/complt other
9.0
11.2
23
27
S01.0
ICD-10 Finland
Open wound of scalp
3.0
11.1
52
188
N30.0
ICD-10 Finland
Acute cystitis
2.4
11.1
90
431
R1260
NOMESCO Finland
Evaluation of communicative skills
5.8
10.8
20
36
N02BF02
ATC
pregabalin; oral
3.2
10.8
45
152
G93.3
ICD-10 Finland
Postviral fatigue syndrome
28.9
10.8
14
5
N04BC06
ATC
cabergoline; oral
28.9
10.8
14
5
N04
ICPC
Restless legs
28.9
10.8
14
5
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.1
10.6
30
78
F02.39
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
+∞
10.5
10
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.4
10.4
87
421
AA5EN
NOMESCO Finland
Brain reseptor or transprot protein distribution isotope imaging
24.1
10.3
14
6
N06AB10
ATC
escitalopram; oral
2.3
10.2
95
482
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.6
9.9
61
255
SPAT1254
SPAT
Administration of medicine
2.4
9.9
74
340
M48.0
ICD-10 Finland
Spinal stenosis
2.3
9.6
79
379
XF606
NOMESCO Finland
Ortostatic test
18.1
9.5
14
8
N02BE01
ATC
paracetamol; systemic, rectal
3.7
9.4
385
3352
C03CA01
ATC
furosemide; systemic
2.0
9.0
148
922
ZY010
NOMESCO Finland
Hospital outpatient
3.8
9.0
28
78
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
24.7
9.0
12
5
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
4.7
8.9
21
47
M54.5
ICD-10 Finland
Low back pain
1.9
8.7
167
1093
N02BF01
ATC
gabapentin; oral
2.4
8.6
62
279
SPAT1301
SPAT
No procedures
1.9
8.6
146
917
WX402
NOMESCO Finland
General anaesthesia
2.0
8.6
109
619
L03
ICPC
Low back symptom/complaint
1.9
8.6
137
843
D12
ICPC
Constipation
3.4
8.5
31
96
UDQ42
NOMESCO Finland
Endoscopic assessment of swallowing function
28.2
8.5
11
*
M01AH05
ATC
etoricoxib; oral
1.9
8.5
274
2109
J01EA01
ATC
trimethoprim; systemic
2.0
8.5
123
732
G23.9
ICD-10 Finland
Degenerative disease of basal ganglia, unspecified
91.9
8.4
9
*
TJD10
NOMESCO Finland
Insertion of other tube into stomach or duodenum
91.9
8.4
9
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
8.4
65
302
N30.9
ICD-10 Finland
Cystitis, unspecified
2.9
8.4
40
146
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
8.4
114
663
AAW01
NOMESCO Finland
Implantation of intracranial stimulation device
+∞
8.4
8
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
11.1
8.4
15
14
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
8.3
201
1409
WX002
NOMESCO Finland
Sedation and analgesia
2.1
8.3
100
556
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
3.3
8.3
32
103
TAW99
NOMESCO Finland
Other minor neurosurgical procedure
14.9
8.3
13
9
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
4.7
8.2
19
42
R60.0
ICD-10 Finland
Localized oedema
2.2
8.2
74
368
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
17.6
8.1
12
7
S72.0
ICD-10 Finland
Fracture of neck of femur
3.7
8.1
26
74
M79.6
ICD-10 Finland
Pain in limb
1.8
8.1
202
1427
UKC02
NOMESCO Finland
Cystoscopy
2.1
8.0
82
428
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
7.5
8.0
18
25
WX725
NOMESCO Finland
Noninvasive ventilation
3.0
7.7
35
124
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
3.5
7.7
26
77
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.0
7.6
35
125
SPAT1262
SPAT
Handing over of treatment supplies
2.1
7.6
86
466
WX110
NOMESCO Finland
Infiltration anesthesia
1.9
7.5
297
2392
A02BC03
ATC
lansoprazole; oral
1.8
7.5
138
884
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.4
7.4
27
84
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
4.3
7.4
19
46
XKD00
NOMESCO Finland
Uroflowmetry
2.1
7.3
75
392
L86
ICPC
Back syndrome with radiating pain
2.7
7.2
38
147
A06AC01
ATC
ispaghula (psylla seeds); oral
1.8
7.1
130
829
M54.4
ICD-10 Finland
Lumbago with sciatica
2.0
7.1
87
486
WX212
NOMESCO Finland
Femoral plexus blockade
4.5
7.0
17
39
X59
ICD-10 Finland
Exposure to unspecified factor
2.0
6.9
87
490
M35.7
ICD-10 Finland
Hypermobility syndrome
11.2
6.8
12
11
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.1
6.7
18
45
A01
ICPC
Pain general/multiple sites
2.2
6.7
60
297
H02.3
ICD-10 Finland
Blepharochalasis
2.6
6.7
40
165
N99
ICPC
Neurological disease other
8.0
6.7
14
18
R63.4
ICD-10 Finland
Abnormal weight loss
3.1
6.6
28
96
F02.30
ICD-10 Finland
Dementia in Parkinson's disease without additional symptoms
70.9
6.4
7
*
G23.2
ICD-10 Finland
Multiple system atrophy, parkinsonian type [MSA-P]
70.9
6.4
7
*
K04.08
ICD-10 Finland
Other specified pulpit
2.7
6.4
34
132
WX704
NOMESCO Finland
Intubation
2.5
6.4
40
169
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.1
6.4
67
353
L17
ICPC
Foot/toe symptom/complaint
1.7
6.4
142
955
Z50.1
ICD-10 Finland
Other physical therapy
2.7
6.3
33
127
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.5
6.3
39
164
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
3.5
6.2
21
62
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
6.2
101
617
S97
ICPC
Chronic ulcer skin
2.4
6.2
41
178
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
3.9
6.2
18
48
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.2
6.1
24
78
W19
ICD-10 Finland
Unspecified fall
2.3
6.1
48
225
K02.1
ICD-10 Finland
Caries of dentine
1.7
6.1
235
1826
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
6.1
114
728
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
6.1
173
1241
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
5.7
6.1
16
29
SPAT1172
SPAT
Guidance concerning hydration
6.2
6.1
15
25
A02BC05
ATC
esomeprazole; systemic
1.7
6.0
176
1269

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
219
1213
2.74
22.14
4.5
3.2
—
—
—
0
0
289
1989
2.56
16.59
7.9
7.0
1.21
1.21
mmol/l
0.32
244
1727
333
2464
2.93
16.35
7.7
4.8
10381.43
3123.83
e6/l
—
7
41
200
1183
2.36
15.98
2.0
1.7
19.58
20.52
nmol/l
0.42
178
984
204
1219
2.35
15.90
2.8
2.1
185.77
177.56
u/l
0.08
199
1150
312
2259
2.63
15.54
6.3
5.0
6.26
6.70
mmol/l
6.13
305
2152
267
1814
2.37
15.11
7.9
6.2
1.20
1.21
mmol/l
1.78
249
1672
151
812
2.37
14.78
1.9
1.8
380.24
17620935.78
pmol/l
0.50
126
664
132
676
2.41
14.37
1.9
1.7
1412.76
1259.30
nmol/l
0.88
97
508
255
1738
2.25
13.76
5.5
4.9
35.70
35.56
g/l
0.15
236
1629
102
474
2.54
13.63
5.5
7.9
1.71
0.88
mmol/l
1.51
87
402
266
1851
2.26
13.55
11.3
13.1
1.17
1.23
inr
1.70
219
1529
202
1268
2.18
13.24
4.4
3.4
20.60
101.04
e6/l
0.93
161
979
198
1240
2.16
12.98
6.0
3.9
7.41
7.40
ph
2.73
155
885
173
1029
2.18
12.92
4.3
3.1
—
0.00
estimate
—
0
6
101
479
2.47
12.85
5.4
7.9
7.41
7.42
ph
0.61
64
279
181
1100
2.16
12.76
4.9
4.3
—
—
—
0
0
67
267
2.81
12.06
4.1
7.1
26.24
24.73
mmol/l
3.16
62
252
178
1094
2.11
12.00
4.3
3.2
0.27
0.40
e6/l
0.77
140
805
99
481
2.40
11.86
5.5
7.8
13.34
12.22
kpa
0.86
94
464
99
481
2.40
11.86
5.5
7.8
5.37
5.04
kpa
3.63
94
464
245
1726
2.05
11.10
2.6
2.2
89.78
97.08
pmol/l
2.17
154
860
246
1745
2.04
10.82
3.0
2.8
—
—
estimate
—
0
0
150
892
2.08
10.80
3.1
2.6
6.06
4.81
e6/l
0.74
140
817
321
2530
2.27
10.47
6.8
4.7
—
2.81
—
0
5
271
2005
2.05
10.42
6.1
4.1
0.02
0.00
estimate
0.49
67
436
268
1992
2.01
9.96
5.9
4.0
0.00
0.00
estimate
-0.00
68
426
236
1689
1.95
9.68
5.1
2.9
130.80
125.81
ug/l
0.16
211
1565
215
1496
1.93
9.55
5.8
4.0
0.00
0.02
estimate
1.06
58
352
156
977
1.97
9.46
2.9
2.2
2.91
3.09
mg/l
0.30
131
842
209
1444
1.92
9.45
5.4
4.0
113.95
118.89
e6/l
0.03
163
1029
270
2032
1.98
9.43
6.1
4.0
0.00
0.02
estimate
0.79
66
403
59
255
2.54
8.97
2.8
4.9
—
—
—
0
0
141
878
1.93
8.53
6.2
4.2
1.02
1.02
kg/l
1.86
96
571
220
1583
1.85
8.42
5.0
3.7
6.26
6.20
ph
0.36
128
862
393
3507
4.51
8.41
26.2
16.9
25.18
23.95
mg/l
0.36
353
2919
180
1231
1.83
8.00
2.9
2.4
—
—
—
0
0
212
1537
1.79
7.65
4.5
4.0
30.26
54.00
ng/l
0.54
171
1160
122
762
1.86
7.11
3.5
3.0
556.45
530.02
mosm/kgh2o
0.79
112
670
106
635
1.90
7.02
2.8
1.8
28.76
29.32
s
0.65
101
614
340
2891
2.07
6.96
7.8
8.5
78.74
79.87
u/l
0.22
325
2736
167
1155
1.76
6.89
5.8
4.1
0.00
0.01
estimate
0.78
57
404
78
428
2.02
6.64
2.0
1.7
—
—
—
0
0
104
635
1.86
6.44
4.5
2.4
2.23
2.32
g/l
0.86
92
585
226
1723
1.70
6.39
2.8
2.4
75.56
78.45
nmol/l
0.86
203
1528
110
688
1.82
6.29
4.5
2.4
13.40
12.77
umol/l
0.36
98
640
187
1367
1.68
6.11
2.7
3.5
2.34
2.36
mmol/l
1.89
177
1239
152
1063
1.69
5.80
4.5
3.4
0.00
0.00
estimate
0.50
54
344
22
72
3.17
5.58
4.6
3.2
—
—
—
0
0
42
196
2.27
5.38
3.0
3.2
4.52
4.49
pmol/l
0.06
37
171
12
18
6.83
5.29
3.2
1.3
67.29
104.08
nmol/l
—
7
13
97
619
1.74
5.08
4.4
3.2
2.85
2.38
e6/l
0.15
47
306
326
2835
1.75
4.87
4.8
4.3
15.11
14.96
pmol/l
0.48
294
2567
94
602
1.73
4.84
4.8
2.3
22.59
22.06
%
0.15
85
562
59
328
1.93
4.79
2.9
4.0
1.21
1.23
mmol/l
1.37
49
280
120
837
1.62
4.42
2.8
2.8
2.43
2.46
mmol/l
2.57
109
756
398
3788
3.29
4.28
37.5
26.0
6.61
6.73
e9/l
0.48
392
3711
398
3788
3.29
4.28
37.5
25.9
248.22
247.01
e9/l
0.16
393
3723
398
3788
3.29
4.28
37.5
25.9
4.32
4.46
e12/l
6.27
392
3709
54
305
1.89
4.19
5.3
3.9
—
—
—
0
0
51
283
1.92
4.17
2.2
3.4
136.84
199.58
ng/l
0.85
44
258
397
3745
3.45
4.09
30.6
22.6
76.09
77.82
umol/l
0.24
392
3703
163
1243
1.52
3.99
2.4
2.5
55.44
65.21
u/l
0.77
152
1147
386
3597
2.42
3.99
22.8
15.3
—
—
—
0
0
305
2656
1.59
3.98
4.6
4.4
—
0.00
—
0
6
109
760
1.59
3.98
5.3
3.9
73.59
286.71
ng/l
2.45
87
634
64
391
1.76
3.85
2.5
1.9
392.84
382.41
nmol/l
0.16
58
369
170
1316
1.50
3.84
2.8
3.2
1041.20
1087.49
ng/l
0.07
143
1127
9
15
6.11
3.83
1.1
1.0
121.11
133.33
nmol/l
—
9
15
64
393
1.75
3.79
5.4
3.3
2.51
1.91
mmol/l
0.65
53
336
74
474
1.69
3.76
1.9
2.8
1.53
1.83
%
3.03
63
428
135
999
1.53
3.76
1.5
1.4
—
—
—
0
0
19
73
2.68
3.69
1.7
1.3
—
—
—
0
0
119
874
1.51
3.38
2.2
1.7
1.05
1.41
mg/l
1.20
104
701
363
3343
1.79
3.37
6.1
5.4
1.90
1.93
mu/l
0.26
334
3068
65
415
1.67
3.34
5.3
3.3
7.36
7.39
ph
1.25
38
241
162
1270
1.46
3.32
3.2
3.2
29.68
32.09
u/l
0.33
151
1194
42
237
1.86
3.28
1.3
1.4
—
54.66
—
0
21
6
7
8.68
3.27
6.7
2.4
—
—
—
0
0
82
563
1.57
3.15
1.3
1.2
—
—
—
0
0
245
2097
1.42
3.00
4.9
6.8
10.52
11.34
umol/l
1.14
230
1993
251
2158
1.43
2.99
7.5
9.8
4.19
4.13
e9/l
0.16
222
1882
16
63
2.60
2.99
1.3
1.2
348.55
293.78
u/ml
0.22
11
27
133
1022
1.45
2.96
4.5
3.1
0.00
0.09
—
5
23
231
1959
1.41
2.96
6.1
6.3
1.65
1.92
e9/l
3.01
207
1717
19
83
2.35
2.88
1.6
1.3
3.67
17.74
e6/l
0.85
12
61
12
38
3.22
2.87
1.4
1.1
—
—
—
0
0
32
173
1.92
2.86
2.1
1.9
—
—
—
0
0
228
1941
1.40
2.79
6.1
6.2
0.04
0.04
e9/l
1.74
200
1649
227
1932
1.40
2.78
6.1
6.2
0.52
0.59
e9/l
6.07
200
1640
53
337
1.66
2.78
11.7
8.4
—
—
—
0
0
19
85
2.30
2.75
1.6
1.3
59.00
1473.03
e6/l
0.54
14
66
22
105
2.16
2.74
4.5
3.1
4.37
1.70
index
0.68
11
63
16
67
2.44
2.66
1.6
1.3
—
—
—
0
0
57
375
1.60
2.62
2.1
3.0
54.98
70.65
e9/l
5.46
39
283
7
16
4.43
2.48
1.0
1.3
172.43
179.73
mmol/24h
—
7
16
230
1990
1.36
2.40
6.1
6.5
0.17
0.19
e9/l
2.74
206
1726
79
574
1.47
2.32
2.7
2.0
—
—
—
0
0
30
172
1.80
2.28
1.8
1.9
1.30
3.66
ug/l
0.69
23
152
195
1659
1.34
2.21
14.2
12.1
0.00
0.00
e9/l
0.41
165
1353
10
36
2.82
2.15
1.1
1.3
20.40
30.41
ng/l
—
10
36
23
124
1.91
2.11
1.6
1.4
254.44
285.55
ug/g
0.31
15
77
50
338
1.55
2.07
2.6
2.4
7.66
6.41
ug/l
0.22
42
303
6
15
4.04
2.04
7.8
3.3
21.17
13.41
mu/l
—
6
15
154
1282
1.32
1.98
6.2
6.2
—
—
—
0
0
7
21
3.37
1.97
3.0
2.2
—
—
—
0
0
66
481
1.44
1.91
2.1
1.7
—
—
—
0
0
24
138
1.79
1.84
2.1
2.0
215.57
264.30
ug/l
0.26
24
129
114
1383
0.76
1.76
4.4
4.1
15.83
7.30
mg/mmol
0.65
79
835
52
370
1.46
1.71
3.7
2.5
29.82
34.71
u/l
0.53
44
299
386
3719
1.73
1.69
12.8
13.0
18.46
25.67
u/l
23.89
368
3605
111
1345
0.76
1.69
3.7
3.4
82.31
41.68
mg/l
0.61
83
854
17
90
1.93
1.67
1.3
1.3
—
—
—
0
0
111
1342
0.76
1.65
3.4
3.4
—
—
—
0
0
104
839
1.32
1.63
1.4
1.3
1.36
1.47
u/ml
0.06
26
225
10
43
2.36
1.60
2.4
1.7
—
—
—
0
0
201
1776
1.26
1.53
6.3
6.4
0.69
0.70
%
0.15
187
1652
59
440
1.40
1.52
2.7
2.3
191.08
141.17
ug/g
0.53
48
354
13
65
2.03
1.50
1.2
1.4
—
—
—
0
0
13
65
2.03
1.50
1.2
1.4
—
—
—
0
0
138
1168
1.27
1.50
5.6
6.2
—
—
—
0
0
13
66
2.00
1.45
1.2
1.3
—
—
—
0
0
13
66
2.00
1.45
1.2
1.3
—
—
—
0
0
5
16
3.15
1.44
4.0
2.1
1.23
1.11
nmol/l
—
5
10
43
306
1.45
1.44
1.9
2.2
—
—
—
0
0
262
2399
1.26
1.42
3.5
3.4
38.00
51.94
u/l
2.01
237
2238
21
127
1.69
1.39
1.7
1.3
32.22
29.35
iu/l
0.16
21
103
9
41
2.22
1.38
1.1
1.2
—
—
—
0
0
9
41
2.22
1.38
1.7
1.3
—
—
—
0
0
6
23
2.63
1.37
1.3
1.7
98.67
82.86
ng/l
—
6
23
101
833
1.28
1.34
3.7
5.0
—
—
—
0
0
200
1785
1.24
1.33
6.3
6.4
2.63
2.83
%
0.79
186
1667
20
121
1.69
1.33
18.6
10.6
—
—
—
0
0
202
1808
1.23
1.30
6.3
6.5
25.38
27.13
%
1.57
188
1708
17
100
1.73
1.25
1.1
1.2
—
—
—
0
0
118
1376
0.80
1.25
3.6
3.3
7.45
7.46
mmol/l
0.00
106
1151
8
36
2.25
1.25
1.3
1.4
—
—
—
0
0
199
1787
1.22
1.22
6.4
6.5
8.33
8.89
%
2.55
186
1671
8
37
2.19
1.22
3.0
1.8
11.36
9.88
%
—
8
37
6
26
2.33
1.19
7.8
2.7
0.50
0.92
index
—
6
26
28
191
1.50
1.17
2.3
2.4
—
—
—
0
0
48
363
1.37
1.17
2.1
4.7
1.36
0.86
%
0.46
14
128
26
175
1.52
1.16
1.4
1.3
—
—
—
0
0
27
186
1.48
1.09
1.3
1.1
—
—
—
0
0
7
32
2.21
1.08
1.0
1.3
—
—
—
0
0
16
98
1.66
1.05
3.1
2.5
8.59
7.91
kpa
1.02
16
98
45
344
1.35
1.04
2.2
4.9
0.45
0.15
%
0.61
11
109
159
1417
1.20
1.01
3.7
3.7
—
0.60
—
0
5
10
54
1.87
0.97
1.5
2.6
1.20
1.19
mmol/l
—
10
54
10
54
1.87
0.97
1.5
2.6
104.80
105.89
mmol/l
—
10
54
10
54
1.87
0.97
1.5
2.6
4.01
3.98
mmol/l
—
10
54
10
54
1.87
0.97
1.2
1.3
—
—
—
0
0
11
62
1.80
0.95
1.2
1.4
—
—
—
0
0
46
359
1.32
0.94
3.0
4.1
7.36
7.36
ph
0.02
36
253
194
1770
1.18
0.93
6.2
6.3
59.33
57.90
%
1.03
188
1685
145
1617
0.84
0.93
2.0
2.0
1.25
1.33
mmol/l
0.72
119
1342
30
219
1.40
0.92
1.4
1.2
49.61
139.99
u/ml
—
7
88
23
161
1.45
0.88
1.1
1.1
—
—
—
0
0
45
354
1.30
0.88
2.3
1.5
—
—
—
0
0
58
474
1.26
0.85
1.4
1.3
—
—
—
0
0
8
45
1.79
0.84
1.4
1.4
—
—
nmol/l
—
0
0
327
3387
0.82
0.79
4.1
4.6
1.16
1.29
mmol/l
3.36
288
3090
44
352
1.28
0.77
2.5
5.1
0.20
0.11
%
—
10
102
26
345
0.74
0.76
1.4
1.5
—
—
—
0
0
11
67
1.66
0.76
1.2
1.3
—
—
—
0
0
60
501
1.23
0.74
1.5
1.5
—
—
—
0
0
15
100
1.52
0.74
1.2
1.5
2856.10
14756.85
e6/l
—
10
75
342
3522
0.82
0.73
4.9
5.4
1.47
1.48
mmol/l
0.17
311
3237
43
346
1.27
0.73
2.3
4.6
0.50
0.37
%
0.27
12
115
9
56
1.62
0.73
1.2
2.8
3.15
4.68
e9/l
—
9
56
54
448
1.24
0.71
3.4
2.8
6.44
7.84
umol/l
0.25
47
403
9
59
1.54
0.69
1.3
1.3
22.92
89.08
mu/l
—
9
53
5
28
1.80
0.66
1.2
3.9
6.84
7.66
mmol/l
—
5
28
18
246
0.72
0.65
1.5
1.4
—
—
—
0
0
20
147
1.38
0.63
3.2
2.5
26.68
24.68
mmol/l
2.10
20
147
20
263
0.75
0.58
1.3
1.4
—
—
—
0
0
81
716
1.16
0.56
1.4
1.3
30.90
38.54
iu/ml
0.29
23
214
136
1250
1.13
0.54
5.1
5.5
1.98
2.23
ug/l
0.36
126
1115
6
39
1.55
0.53
1.8
1.3
—
—
—
0
0
85
758
1.15
0.53
1.7
1.4
3.03
2.60
g/l
0.23
47
443
346
3540
0.85
0.53
5.0
5.5
4.53
4.60
mmol/l
0.68
313
3277
352
3593
0.85
0.49
5.7
6.3
2.67
2.67
mmol/l
0.03
319
3312
20
155
1.31
0.47
1.3
1.2
—
3.43
—
0
8
34
284
1.22
0.45
1.2
1.2
—
—
—
0
0
17
130
1.32
0.44
1.6
1.6
28.96
13.80
u/ml
—
5
22
14
104
1.36
0.43
5.5
4.5
—
—
—
0
0
5
31
1.62
0.43
1.2
1.2
—
—
—
0
0
5
33
1.52
0.41
1.0
1.2
—
—
—
0
0
111
1025
1.11
0.41
2.3
2.8
326.59
347.44
umol/l
1.08
95
880
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
2.8
—
6.87
—
0
16
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.6
—
—
—
0
0
5
34
1.48
0.40
1.4
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.8
—
—
—
0
0
5
36
1.39
0.38
1.0
1.2
—
—
—
0
0
356
3495
1.15
0.38
5.1
5.5
5.87
6.01
mmol/l
1.41
316
3208
14
179
0.77
0.36
1.1
1.6
—
—
—
0
0
31
264
1.19
0.36
3.3
3.2
7.43
7.42
ph
1.10
24
207
36
311
1.17
0.35
5.4
2.3
6.32
6.04
ph
1.09
25
204
69
753
0.90
0.32
3.7
3.2
0.66
0.75
ug/l
0.85
47
501
7
54
1.30
0.30
1.0
1.5
—
—
—
0
0
7
54
1.30
0.30
1.0
1.5
—
—
—
0
0
7
54
1.30
0.30
1.0
1.5
—
—
—
0
0
7
54
1.30
0.30
1.0
1.5
—
—
—
0
0
8
106
0.75
0.29
1.5
1.3
—
—
—
0
0
8
64
1.25
0.27
2.1
1.2
—
—
—
0
0
11
86
1.29
0.26
1.3
1.2
—
—
—
0
0
47
426
1.12
0.26
2.3
1.5
—
—
—
0
0
71
659
1.09
0.25
1.4
1.3
1.47
12.60
u/ml
3.63
27
247
16
133
1.21
0.24
1.9
3.1
1.49
1.87
ratio
—
9
77
58
534
1.10
0.24
1.4
1.3
471.11
501.49
titre
—
9
134
16
190
0.84
0.24
3.1
3.2
—
—
—
0
0
5
38
1.32
0.23
2.4
2.8
—
—
—
0
0
5
39
1.29
0.23
2.8
1.6
—
—
—
0
0
5
41
1.22
0.22
1.6
1.2
—
—
—
0
0
16
135
1.19
0.21
1.4
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
96.86
—
0
11
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
2.4
—
—
—
0
0
29
259
1.13
0.21
1.2
1.2
—
—
—
0
0
10
80
1.26
0.20
2.6
4.3
7.00
29.80
mg/l
—
5
59
7
59
1.19
0.18
1.9
3.1
—
—
—
0
0
52
486
1.08
0.17
2.0
3.2
5.81
4.89
e9/l
0.19
44
419
8
70
1.15
0.16
2.3
2.4
—
—
—
0
0
41
441
0.92
0.16
2.8
4.4
2.21
37.34
ug/l
1.21
33
370
6
77
0.78
0.15
1.5
1.1
—
—
—
0
0
10
83
1.21
0.15
1.3
2.7
55.30
59.82
%
—
10
83
26
236
1.11
0.15
1.9
1.4
—
—
—
0
0
41
383
1.08
0.14
2.9
2.1
0.00
0.04
estimate
—
7
75
11
127
0.86
0.12
1.5
1.4
1.30
1.20
g/l
0.38
11
122
10
85
1.18
0.12
1.2
1.2
1.52
1.56
g/l
—
10
85
11
95
1.16
0.11
1.6
1.6
—
—
—
0
0
52
495
1.06
0.11
1.4
1.3
—
—
—
0
0
341
3435
0.96
0.10
7.0
6.9
39.12
39.63
mmol/mol
0.56
313
3218
144
1471
0.97
0.10
2.1
2.2
—
—
—
0
0
12
106
1.14
0.10
1.1
1.1
—
—
—
0
0
5
45
1.11
0.10
1.0
1.2
—
—
—
0
0
11
124
0.88
0.09
1.5
1.3
0.25
0.24
g/l
0.23
11
119
8
74
1.08
0.07
2.3
1.5
—
—
—
0
0
9
88
1.02
0.07
1.1
1.2
10.22
11.26
u/l
—
9
69
11
121
0.91
0.06
1.3
1.3
—
2.56
—
0
18
17
179
0.95
0.03
1.2
1.3
—
—
—
0
0
10
94
1.07
0.01
1.2
1.2
0.88
0.92
g/l
—
10
94
12
122
0.98
0.00
2.0
1.7
—
—
—
0
0
16
159
1.01
0.00
1.9
3.0
—
—
—
0
0
36
359
1.00
0.00
1.5
1.4
—
—
—
0
0
37
367
1.01
0.00
1.5
1.6
—
—
—
0
0
5
51
0.98
0.00
1.0
1.1
—
—
—
0
0
5
51
0.98
0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
0.02
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
11
110
1.00
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
6.0
—
8.63
—
0
6
0
9
0.00
-0.00
0.0
1.1
—
49.20
—
0
9
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.5
—
7111.38
—
0
8
0
7
0.00
-0.00
0.0
1.1
—
25.29
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
21
210
1.00
-0.00
2.5
2.3
0.00
0.02
estimate
—
5
59
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
8
83
0.96
-0.00
1.4
2.5
4.04
9.33
pmol/l
—
8
83
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
23.10
—
0
5
0
9
0.00
-0.00
0.0
2.2
—
2.78
—
0
9
0
8
0.00
-0.00
0.0
1.4
—
9.95
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
1.81
—
0
7

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: PDMED_ROTIGOTINE – Use of rotigotine

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).