Benign neoplasm: Orbit, unspecified

CD2_BENIGN_ORBIT_NOS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D31.6&
  • Hospital discharge: ICD-9 2241
  • Hospital discharge: ICD-8 22405
  • Cause of death: ICD-10 D31.6&
  • Cause of death: ICD-9 2241
  • Cause of death: ICD-8 22405

2 out of 7 registries used, show all original rules.

250

4. Check minimum number of events

None

250

5. Include endpoints

None

250

6. Filter based on genotype QC (FinnGen only)

227

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D31
Name in latin
Neoplasma benignum orbitae non specificatum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1703 988 701
Only index persons 1480 873 607
Unadjusted period prevalence (%)
Whole population 0.02 0.03 0.02
Only index persons 0.03 0.03 0.02
Median age at first event (years)
Whole population 50.29 50.56 49.71
Only index persons 49.65 50.35 48.65

-FinnGen-

Key figures

All Female Male
Number of individuals 227 150 77
Unadjusted period prevalence (%) 0.05 0.05 0.04
Median age at first event (years) 54.91 53.08 58.46

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
234
Matched controls
2340
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D31.6
ICD-10 Finland
Benign neoplasm: Orbit, unspecified
+∞
272.1
205
*
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
300.2
49.0
48
*
CAA30
NOMESCO Finland
Biopsy of orbit
+∞
39.7
37
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
5.6
22.5
49
106
CAB00
NOMESCO Finland
Anterior orbitotomy with excision of lesion
+∞
20.1
19
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
8.6
20.0
27
35
H05.2
ICD-10 Finland
Exophthalmic conditions
114.8
19.9
21
*
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
+∞
17.9
17
*
22405
ICD-8 Finland
Benign neoplasm of eye, Orbitae
+∞
16.9
16
*
2241A
ICD-9 Finland
Benign neoplasm of eye, Orbit
+∞
16.9
16
*
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
7.8
16.4
24
34
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.5
16.2
74
275
XCK00
NOMESCO Finland
Perimetry
5.0
14.6
34
77
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
36.5
13.7
17
5
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
36.5
13.7
17
5
CA1DG
NOMESCO Finland
Eye and orbita very extensive MRI examination with high intensity magnet
+∞
13.7
13
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.6
11.9
132
771
CAB10
NOMESCO Finland
Lateral orbitotomy with excision of lesion
+∞
11.5
11
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
4.5
11.5
30
74
H05.9
ICD-10 Finland
Disorder of orbit, unspecified
+∞
10.5
10
*
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
14.0
10.3
17
13
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
27.4
9.9
13
5
XCK10
NOMESCO Finland
Photography of fundus of eye
3.4
9.6
38
126
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
104.1
9.5
10
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.8
9.3
56
237
H57.1
ICD-10 Finland
Ocular pain
4.7
9.1
22
51
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
8.8
131
835
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
17.1
8.7
13
8
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
13.4
8.5
14
11
C69.60
ICD-10 Finland
Malignant tumor in orbit without histology
93.3
8.5
9
*
H05.1
ICD-10 Finland
Chronic inflammatory disorders of orbit
+∞
8.4
8
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.3
8.3
103
605
CS494
NOMESCO Finland
Other visual field testing
7.3
8.3
19
28
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
13.7
8.0
13
10
H04.10
ICD-10 Finland
Dry eye syndrome
2.8
7.7
43
174
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
7.6
74
390
C69.63
ICD-10 Finland
Malignant tumor of orbital carcinoma
+∞
7.3
7
*
9699/3-C69.6
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of orbit, NOS
+∞
7.3
7
*
WX002
NOMESCO Finland
Sedation and analgesia
2.4
7.3
59
286
AA1AD
NOMESCO Finland
CT of head and brain
2.2
7.1
88
511
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
7.0
97
586
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.8
6.9
37
146
CFA20
NOMESCO Finland
Biopsy of conjunctiva
41.3
6.8
8
*
D36.1
ICD-10 Finland
Benign neoplasm: Peripheral nerves and autonomic nervous system
23.3
6.7
9
*
XW000
NOMESCO Finland
Bone marrow biopsy
4.3
6.5
17
42
D31.5
ICD-10 Finland
Benign neoplasm: Lacrimal gland and duct
+∞
6.3
6
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
6.3
6.1
15
25
H53.2
ICD-10 Finland
Diplopia
4.2
6.0
16
40

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
41
177
2.60
6.45
1.4
1.3
—
—
—
0
0
149
1077
2.06
6.44
6.6
5.9
1.88
1.87
e9/l
0.02
128
962
146
1051
2.03
6.34
6.6
5.9
0.56
0.57
e9/l
0.10
122
914
160
1196
2.07
6.19
10.2
9.6
4.13
4.09
e9/l
0.08
132
1054
145
1056
1.98
5.92
6.7
5.9
0.04
0.04
e9/l
0.12
121
916
148
1093
1.96
5.71
6.9
6.1
0.19
0.19
e9/l
0.09
126
967
131
940
1.89
5.39
6.9
6.8
1.21
1.21
mmol/l
0.50
124
867
49
255
2.17
5.03
1.3
1.2
—
—
—
0
0
133
979
1.83
4.86
7.1
5.9
58.31
57.74
%
0.26
127
939
131
961
1.83
4.83
7.5
6.0
3.07
2.76
%
0.65
124
909
99
668
1.84
4.79
8.4
5.7
—
—
—
0
0
131
964
1.82
4.75
7.7
6.1
9.10
8.81
%
0.47
125
916
13
26
5.23
4.70
1.3
1.0
—
—
—
0
0
50
271
2.07
4.61
1.3
1.4
407.27
558.26
titre
0.27
11
69
130
961
1.79
4.59
7.7
6.0
0.78
0.68
%
1.14
124
903
114
812
1.79
4.55
2.6
2.0
—
—
—
0
0
93
637
1.76
4.15
1.7
1.7
22.60
21.73
nmol/l
0.18
83
528
222
1994
3.21
4.15
19.5
16.2
22.46
22.86
mg/l
0.06
194
1629
127
954
1.72
4.06
15.5
13.6
1.21
1.23
inr
0.14
112
790
93
643
1.74
3.99
5.4
6.1
—
—
—
0
0
120
894
1.70
3.90
5.0
3.8
6.45
6.23
ph
1.05
58
507
134
1030
1.70
3.86
8.3
7.7
1.21
1.21
mmol/l
0.04
122
893
28
129
2.33
3.82
1.4
1.3
11.90
24.39
au/ml
—
5
11
143
1126
1.69
3.70
5.3
4.2
0.00
6.60
estimate
0.50
18
246
30
145
2.23
3.67
2.7
2.5
29.26
9.99
au/ml
—
5
9
18
68
2.78
3.66
1.2
1.1
—
—
—
0
0
144
1143
1.68
3.55
5.4
4.3
0.00
0.00
estimate
-0.00
18
233
88
621
1.67
3.39
3.8
3.1
0.27
0.52
e6/l
0.93
53
452
14
48
3.04
3.36
1.0
1.1
—
—
—
0
0
140
1118
1.63
3.25
5.3
4.2
0.00
0.00
estimate
-0.00
18
243
119
918
1.60
3.15
6.6
4.9
36.42
35.83
g/l
0.66
112
864
9
20
4.64
3.14
1.3
1.1
—
—
—
0
0
122
948
1.60
3.12
2.4
2.1
95.37
96.97
pmol/l
0.15
70
472
92
669
1.62
3.10
2.6
2.4
—
—
—
0
0
12
37
3.36
2.98
1.2
1.2
2.00
4.29
u/ml
—
7
17
209
1882
2.03
2.91
6.6
5.4
1.81
1.91
mu/l
0.49
199
1735
41
243
1.83
2.88
7.5
10.5
0.75
1.00
mmol/l
0.14
34
207
225
2109
2.74
2.87
25.5
21.0
77.71
75.40
umol/l
0.42
225
2086
41
248
1.79
2.70
7.6
10.4
7.43
7.42
ph
0.53
21
154
167
1428
1.59
2.62
4.3
4.2
—
0.20
—
0
5
97
738
1.54
2.59
4.7
3.3
2.34
2.36
mmol/l
0.64
87
665
53
350
1.66
2.56
3.7
2.9
4.61
2.69
e6/l
0.28
17
177
7
16
4.47
2.49
1.3
1.1
—
—
—
0
0
212
1942
1.97
2.44
5.2
5.0
5.88
5.91
mmol/l
0.13
193
1783
220
2043
2.28
2.42
23.1
19.4
3.96
3.96
mmol/l
0.05
220
1998
34
201
1.81
2.41
1.8
2.1
—
0.00
estimate
—
0
44
115
923
1.48
2.31
9.7
11.7
0.00
0.00
e9/l
0.61
83
754
180
1587
1.58
2.28
5.4
4.4
14.71
14.84
pmol/l
0.30
172
1442
7
18
3.97
2.27
3.6
2.7
—
—
—
0
0
57
784
0.64
2.25
3.2
3.3
—
—
—
0
0
88
672
1.50
2.25
5.5
3.4
—
—
—
0
0
219
2039
2.16
2.24
23.0
19.3
139.60
139.66
mmol/l
0.14
219
1998
93
722
1.48
2.18
4.2
3.2
18.20
134.40
e6/l
0.71
62
553
51
348
1.60
2.15
3.1
3.4
0.82
0.82
mmol/l
0.12
45
328
83
633
1.48
2.11
4.2
4.1
7.39
7.40
ph
1.22
56
452
28
163
1.82
2.10
1.5
1.5
—
—
—
0
0
9
31
2.98
2.09
1.2
1.4
—
—
—
0
0
7
20
3.57
2.07
1.1
1.5
—
—
—
0
0
119
977
1.44
2.05
3.1
2.9
—
—
estimate
—
0
0
188
1688
1.58
2.05
22.5
20.1
13.65
13.63
%
0.08
188
1671
74
555
1.49
2.04
2.6
2.1
2.68
2.81
mg/l
0.27
62
485
203
1859
1.69
2.01
4.3
4.3
1.32
1.26
mmol/l
0.57
183
1707
177
1571
1.52
2.01
9.5
8.1
75.43
78.15
u/l
0.43
171
1491
227
2168
2.57
2.00
30.5
24.4
133.44
134.28
g/l
0.41
227
2148
227
2166
2.60
2.00
30.4
24.4
6.81
6.66
e9/l
0.38
221
2124
227
2166
2.60
2.00
31.2
24.8
39.82
40.17
%
0.44
227
2146
227
2166
2.60
2.00
30.3
24.3
4.45
4.46
e12/l
0.14
221
2122
227
2166
2.60
2.00
30.2
24.2
30.18
30.31
pg
0.60
227
2147
227
2166
2.60
2.00
30.3
24.2
90.78
91.15
fl
0.64
227
2147
7
21
3.40
1.98
1.3
1.1
—
—
—
0
0
102
818
1.44
1.97
5.0
3.9
26.91
106.99
e6/l
2.34
64
569
8
27
3.03
1.95
2.3
2.1
—
—
—
0
0
211
1957
1.80
1.93
5.2
5.1
1.46
1.49
mmol/l
0.43
196
1810
76
579
1.46
1.92
4.3
4.3
—
—
—
0
0
57
417
1.49
1.75
5.0
4.0
20.36
315.46
ng/l
2.23
42
336
64
480
1.46
1.74
2.7
1.8
1.21
1.34
mg/l
0.11
50
374
185
1678
1.49
1.69
26.9
20.5
332.34
331.89
g/l
0.30
185
1671
6
19
3.21
1.67
1.0
1.1
—
—
—
0
0
213
2000
1.72
1.59
6.3
5.9
2.73
2.70
mmol/l
0.15
201
1849
18
100
1.87
1.58
3.6
3.8
36.80
36.95
°c
1.38
18
100
16
86
1.92
1.54
3.7
3.5
—
—
—
0
0
210
1968
1.65
1.54
5.3
5.2
4.66
4.64
mmol/l
0.13
198
1827
49
357
1.47
1.53
1.9
1.6
—
—
—
0
0
155
1373
1.38
1.53
3.2
3.4
35.99
46.10
u/l
2.01
148
1302
40
281
1.51
1.49
1.3
1.3
—
—
—
0
0
202
1881
1.54
1.47
6.7
6.4
38.98
39.21
mmol/mol
0.15
193
1769
6
22
2.77
1.44
1.5
3.7
—
—
—
0
0
42
301
1.48
1.43
7.6
7.1
105.29
104.24
mmol/l
0.94
42
301
23
143
1.67
1.41
2.7
2.7
8.20
13.32
nmol/l
1.97
18
132
51
382
1.43
1.38
1.4
1.3
15.29
34.02
iu/ml
1.89
14
107
40
287
1.47
1.35
2.7
2.2
115.73
119.42
ug/g
0.03
32
224
47
349
1.43
1.34
1.3
1.3
1.22
9.92
u/ml
2.43
14
131
27
178
1.58
1.33
9.7
9.5
—
—
—
0
0
6
24
2.54
1.31
1.8
1.2
369.33
293.79
mu/l
—
6
19
5
18
2.81
1.29
1.2
1.2
—
—
—
0
0
6
25
2.44
1.25
1.0
1.1
—
—
—
0
0
85
704
1.33
1.24
3.3
3.2
7.56
7.65
mmol/l
0.07
72
595
47
355
1.41
1.22
3.2
2.4
12.86
13.34
umol/l
0.17
42
333
82
679
1.32
1.19
3.9
3.9
9.79
10.14
mg/mmol
0.02
45
418
57
447
1.36
1.19
4.1
2.6
2.45
2.45
mmol/l
0.04
51
396
0
34
0.00
1.17
0.0
2.5
—
0.97
—
0
21
80
662
1.32
1.17
3.5
3.3
50.14
60.79
mg/l
0.14
47
423
26
176
1.54
1.16
4.1
3.9
7.35
7.36
ph
0.10
15
121
8
39
2.09
1.16
1.0
1.2
—
—
—
0
0
12
65
1.89
1.15
1.2
1.4
—
—
—
0
0
7
30
2.37
1.13
1.1
1.3
—
—
—
0
0
13
73
1.83
1.13
1.5
1.5
358.37
217.25
miu/ml
—
6
36
13
75
1.78
1.05
1.5
1.9
801.15
309.93
ug/l
0.48
13
69
20
131
1.58
1.04
6.6
7.6
24.50
24.85
mmol/l
0.17
20
131
29
207
1.46
1.03
4.1
2.6
37.58
29.15
u/l
0.55
24
172
216
2070
1.57
1.02
16.4
14.3
—
—
—
0
0
26
183
1.47
0.99
2.1
3.1
68.73
74.13
e9/l
0.35
18
137
5
23
2.20
0.98
1.0
1.1
—
—
—
0
0
0
30
0.00
0.98
0.0
1.5
—
0.48
—
0
25
35
264
1.38
0.93
1.9
1.6
—
—
—
0
0
31
229
1.41
0.93
1.7
1.8
—
—
—
0
0
6
28
2.17
0.92
1.2
1.1
—
—
—
0
0
11
64
1.75
0.87
4.0
5.8
45.48
23.33
mg/l
0.58
11
54
11
64
1.75
0.87
4.0
5.7
67.57
59.47
mg/l
0.10
11
54
60
496
1.28
0.87
6.9
4.6
1.02
1.02
kg/l
0.24
40
330
19
131
1.49
0.81
3.5
7.8
—
—
—
0
0
12
74
1.66
0.80
3.3
2.2
1150.92
7560.05
u/l
—
6
23
8
48
1.69
0.79
1.1
1.2
3.30
3.77
mmol/l
—
8
43
31
237
1.36
0.77
1.2
1.3
—
—
—
0
0
6
34
1.78
0.77
1.0
1.1
—
—
—
0
0
0
28
0.00
0.76
0.0
1.4
—
0.17
—
0
17
28
212
1.36
0.74
4.1
4.2
2.22
39.46
ug/l
0.60
21
173
49
404
1.27
0.73
2.3
2.1
—
—
—
0
0
92
814
1.21
0.72
4.5
4.0
20.16
42.13
ng/l
2.35
66
585
7
40
1.77
0.72
2.0
1.4
—
—
—
0
0
16
110
1.49
0.70
1.5
2.5
—
—
—
0
0
7
42
1.69
0.69
4.3
1.6
—
—
—
0
0
5
27
1.87
0.69
1.0
1.0
—
—
—
0
0
23
171
1.38
0.69
2.4
4.6
1.00
0.55
%
0.58
11
46
32
252
1.31
0.67
1.6
1.5
—
—
—
0
0
43
353
1.27
0.66
1.6
1.6
1142.72
1200.00
nmol/l
0.16
33
263
18
129
1.43
0.65
2.3
2.4
0.73
0.60
%
0.73
18
129
19
138
1.41
0.65
3.3
2.8
—
—
—
0
0
5
29
1.74
0.64
1.2
1.4
—
—
—
0
0
5
29
1.74
0.64
1.2
1.4
—
—
—
0
0
5
29
1.74
0.64
1.2
1.4
—
—
—
0
0
5
29
1.74
0.64
1.2
1.4
—
—
—
0
0
31
245
1.31
0.64
2.1
1.7
—
—
—
0
0
38
311
1.26
0.61
1.8
2.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
0
22
0.00
0.59
0.0
4.4
—
7.24
—
0
22
8
53
1.53
0.59
1.1
1.1
—
—
—
0
0
6
37
1.64
0.56
1.2
1.3
—
—
—
0
0
10
66
1.54
0.53
3.6
2.8
1.38
1.49
mg/l
—
10
57
69
611
1.18
0.52
1.5
1.5
—
—
—
0
0
6
40
1.51
0.52
1.5
1.5
—
—
—
0
0
13
92
1.44
0.51
2.3
1.9
—
—
—
0
0
7
50
1.41
0.45
2.0
2.1
59.00
56.49
%
—
7
50
17
131
1.32
0.43
2.4
2.4
1.29
1.15
%
0.41
17
131
5
31
1.63
0.43
2.0
1.5
0.37
0.48
nmol/l
—
5
23
8
58
1.39
0.42
1.3
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
14
182
0.75
0.41
1.6
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
5.4
—
15.69
—
0
17
5
34
1.48
0.40
1.0
1.1
—
—
—
0
0
13
97
1.36
0.40
3.6
1.9
—
—
—
0
0
5
35
1.44
0.39
1.4
1.3
—
—
—
0
0
12
89
1.37
0.38
1.1
1.2
—
—
—
0
0
22
180
1.25
0.37
2.5
5.1
0.00
0.33
%
—
8
40
5
37
1.36
0.37
1.6
1.2
13.08
22.72
u/l
—
5
32
13
100
1.32
0.34
2.0
2.0
—
0.00
estimate
—
0
34
14
109
1.30
0.34
1.2
1.2
—
—
—
0
0
37
327
1.16
0.30
3.0
3.3
0.90
0.79
ug/l
0.25
26
212
21
176
1.21
0.30
1.9
4.7
0.00
0.25
%
—
7
44
22
186
1.20
0.29
1.9
4.6
0.75
0.85
%
—
8
55
26
224
1.18
0.28
1.7
1.8
—
—
—
0
0
8
67
1.20
0.26
1.3
1.1
—
—
—
0
0
47
429
1.12
0.25
1.5
1.7
410.31
450.29
pmol/l
0.52
39
353
16
134
1.21
0.23
1.3
1.3
50.70
352.36
u/ml
1.61
16
124
59
634
0.91
0.23
3.7
3.6
0.00
0.00
estimate
-0.00
17
192
0
10
0.00
0.21
0.0
4.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
3.1
—
0.90
—
0
10
17
145
1.19
0.21
1.2
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
0.06
—
0
5
0
13
0.00
0.21
0.0
3.8
—
—
—
0
0
6
48
1.26
0.20
1.2
1.2
—
—
—
0
0
14
165
0.84
0.20
6.9
4.3
—
—
—
0
0
22
195
1.14
0.18
1.5
1.5
—
—
—
0
0
91
872
1.07
0.17
6.0
4.1
0.20
0.02
estimate
0.42
15
202
5
66
0.75
0.17
1.6
1.2
—
—
—
0
0
5
66
0.75
0.17
12.8
8.8
—
—
—
0
0
91
877
1.06
0.14
2.2
2.0
1.36
1.34
mmol/l
0.11
78
730
61
639
0.94
0.13
7.6
4.3
0.00
0.01
estimate
0.50
17
225
22
204
1.09
0.09
1.5
1.5
—
—
—
0
0
47
490
0.95
0.08
2.8
4.9
—
—
—
0
0
6
58
1.04
0.08
2.3
1.9
—
—
—
0
0
5
64
0.78
0.08
1.2
1.4
—
—
—
0
0
52
502
1.05
0.07
1.3
1.3
0.92
0.94
u/ml
—
9
125
12
109
1.11
0.06
1.1
1.2
—
—
—
0
0
18
190
0.94
0.04
1.4
1.3
—
—
—
0
0
22
218
1.01
0.00
5.6
3.4
7.37
7.38
ph
0.85
11
121
45
453
0.99
0.00
1.6
1.4
2.15
2.53
g/l
0.80
30
257
9
99
0.91
0.00
1.0
1.1
—
—
—
0
0
6
63
0.95
-0.00
1.3
1.2
1.64
1.57
g/l
—
6
63
0
7
0.00
-0.00
0.0
6.0
—
57.96
—
0
7
8
82
0.97
-0.00
1.1
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1.20
—
0
5
0
5
0.00
-0.00
0.0
3.0
—
2.40
—
0
5
5
54
0.92
-0.00
1.0
2.0
—
—
—
0
0
8
80
1.00
-0.00
1.1
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
41.55
—
0
6
0
5
0.00
-0.00
0.0
4.8
—
41.60
—
0
5
8
81
0.99
-0.00
1.1
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
0.00
—
0
7
0
5
0.00
-0.00
0.0
3.0
—
10916.40
—
0
5
6
63
0.95
-0.00
1.3
1.2
0.82
0.89
g/l
—
6
63
7
71
0.99
-0.00
2.4
2.6
—
—
—
0
0
6
62
0.97
-0.00
2.7
3.2
7.40
7.41
ph
—
6
62
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
79
1.01
-0.00
1.1
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
75
0.93
-0.00
1.1
1.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_ORBIT_NOS and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_ORBIT_NOS 1.274 [1.0, 1.63] 0.051
Birth year 0.99 [0.98, 1.0] 0.051

During the follow-up period (1.1.1998 — 31.12.2019), 108 out of 648 females with CD2_BENIGN_ORBIT_NOS died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_ORBIT_NOS 1.337 [1.0, 1.79] 0.053
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 90 out of 444 males with CD2_BENIGN_ORBIT_NOS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_ORBIT_NOS.

N-year risk Females Males
1 0.107% 0.224%
5 0.624% 1.468%
10 1.459% 3.587%
15 2.954% 6.69%
20 5.353% 11.526%

Relationships between endpoints

Index endpoint: CD2_BENIGN_ORBIT_NOS – Benign neoplasm: Orbit, unspecified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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