lip cancer: Tumors or cancer of the LIP.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
879 |
4. Check minimum number of eventsNone |
879 |
5. Include endpointsNone |
879 |
6. Filter based on genotype QC (FinnGen only) |
782 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D10
- Name in latin
- Neoplasma benignum labii (oris)
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Lip
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of mouth and pharynx
- Benign neoplasms
- Neoplasms
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5939 | 2865 | 3040 |
| Only index persons | 5167 | 2575 | 2592 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.08 | 0.08 |
| Only index persons | 0.10 | 0.09 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 56.86 | 56.25 | 57.39 |
| Only index persons | 55.08 | 55.45 | 54.71 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 782 | 401 | 381 |
| Unadjusted period prevalence (%) | 0.16 | 0.14 | 0.17 |
| Median age at first event (years) | 59.50 | 56.07 | 63.11 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 814
- Matched controls
- 8140
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
EAA10
NOMESCO Finland
Excision of lesion of lip
95.7
307.7
238
35
D10.09
ICD-10 Finland
Benign tumor of the lip UNS
+∞
296.5
266
*
D10.04
ICD-10 Finland
Lower lip tumor in the lower lip mucosa
+∞
227.0
207
*
TEA00
NOMESCO Finland
Biopsy of lip
45.7
162.4
97
24
D10.00
ICD-10 Finland
Upper lip tumor in upper lip on lip lip border
+∞
134.2
125
*
D10.01
ICD-10 Finland
Uper lip tumor in the upper lip mucosa
+∞
75.2
71
*
D10.03
ICD-10 Finland
Lower lip tumor in the lower lip at the lip red border
+∞
62.3
59
*
D10.0
ICD-10 Finland
Benign neoplasm: Lip
+∞
46.3
44
*
21000
ICD-8 Finland
Benign neoplasm of buccal cavity and pharynx, Lip
+∞
43.1
41
*
8070/3-C00.1
ICD-O-3
Squamous cell carcinoma, NOS, of external lower lip
199.0
37.1
38
*
2100A
ICD-9 Finland
Benign neoplasm of lip, oral cavity and pharynx, Lip
+∞
30.4
29
*
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
6.5
28.2
47
76
C00.1
ICD-10 Finland
Malignant neoplasm: External lower lip
74.9
25.9
29
*
C44.02
ICD-10 Finland
Spinocellular carcinoma of the lip skin
268.7
25.8
26
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
3.0
24.2
122
456
D18.0
ICD-10 Finland
Haemangioma, any site
6.1
23.3
41
70
EAA30
NOMESCO Finland
Partial excision of lower lip
64.4
22.0
25
*
4381
FHL
Exemption of local change
204.8
19.6
20
*
D10.05
ICD-10 Finland
Lower lip tumor in lower lip mucosa and on lip lip border
+∞
18.8
18
*
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
4.3
13.8
36
87
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.0
13.5
168
929
D20
ICPC
Mouth/tongue/lip symptom/complaint
3.0
12.8
58
203
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
3.6
12.7
42
121
EKA10
NOMESCO Finland
iopsy of buccal mucosa
4.2
11.9
32
79
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.6
10.9
64
257
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
3.4
10.2
36
108
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.8
10.0
190
1196
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
4.3
9.7
25
60
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.2
9.4
37
119
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
3.3
9.4
36
114
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
3.5
9.1
31
91
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
9.0
244
1685
SXA10
NOMESCO Finland
Oral mucosal sampling
5.0
8.9
19
39
K13.03
ICD-10 Finland
Keilit UNS
14.2
8.7
14
10
L57.0
ICD-10 Finland
Actinic keratosis
1.9
8.3
108
603
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.0
8.2
92
486
K13.09
ICD-10 Finland
Disease of the lips UNS
33.7
8.1
10
*
C00.9
ICD-10 Finland
Malignant neoplasm: Lip, unspecified
33.7
8.1
10
*
SAA02
NOMESCO Finland
Basic examination of mouth
1.5
8.0
495
4088
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.9
8.0
107
602
SPAT1153
SPAT
Removal of sutures
1.6
7.8
252
1805
D10.9
ICD-10 Finland
Benign neoplasm: Pharynx, unspecified
25.3
7.6
10
*
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
7.6
112
650
S18
ICPC
Laceration/cut
1.5
7.6
383
3018
K13.78
ICD-10 Finland
Other change in the oral mucosa
3.3
7.4
28
88
K13.08
ICD-10 Finland
Other disease of the lips
80.8
7.4
8
*
Z01.2
ICD-10 Finland
Dental examination
1.5
7.3
344
2663
K13.29
ICD-10 Finland
Indefinite leukoplakia
5.7
7.1
19
34
K11.69
ICD-10 Finland
Mukocele UNS
7.1
7.0
16
23
R01AD09
ATC
mometasone; nasal
1.5
6.9
334
2591
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
6.9
534
4551
K11.6
ICD-10 Finland
Mucocele of salivary gland
11.1
6.8
12
11
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
6.6
278
2093
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
3.5
6.6
22
64
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
3.6
6.5
21
60
D23.0
ICD-10 Finland
Benign neoplasm: Skin of lip
8.2
6.3
13
16
H02AB07
ATC
prednisone; oral
1.7
6.3
113
693
EKB00
NOMESCO Finland
Excision of tumour or other lesion of cheek
9.3
6.3
12
13
D10.07
ICD-10 Finland
Lip tumor in both lips of the mucous membrane
+∞
6.3
6
*
EJB00
NOMESCO Finland
Excision of ranula
+∞
6.3
6
*
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
2.4
6.2
41
175
D83
ICPC
Mouth/tongue/lip disease
5.8
6.2
16
28
K11.60
ICD-10 Finland
Ranula
12.6
6.1
10
8
S21
ICPC
Skin texture symptom/complaint
1.7
6.1
121
765
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
6.1
95
561
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
150
908
1.80
8.90
5.0
5.0
35.55
32.30
%
2.38
85
590
459
3741
1.52
7.79
6.8
7.2
1.22
1.21
mmol/l
0.53
383
3216
421
3388
1.50
7.47
6.3
6.4
1.21
1.21
mmol/l
0.09
364
3100
133
824
1.73
7.21
8.1
7.6
—
—
—
0
0
619
5439
1.58
7.00
8.9
8.5
79.72
80.18
u/l
0.07
583
5154
408
3322
1.46
6.47
2.4
2.2
97.58
95.51
pmol/l
0.36
209
1737
460
3913
1.40
5.28
2.8
2.9
—
—
—
0
0
495
4295
1.39
4.87
5.1
5.0
6.84
6.71
mmol/l
0.62
473
4094
584
5242
1.40
4.48
5.2
4.5
12.75
12.70
mm/h
0.03
520
4866
21
78
2.74
4.28
1.9
1.4
38.29
63.57
%
1.75
14
53
232
1809
1.40
4.25
2.9
2.4
—
—
—
0
0
469
4084
1.35
4.22
9.7
9.7
3.90
4.16
e9/l
2.15
405
3575
24
97
2.52
4.16
1.7
1.3
—
—
—
0
0
24
97
2.52
4.16
1.7
1.3
—
—
—
0
0
19
68
2.84
4.14
1.7
1.5
13.91
30.31
u/l
1.42
11
56
24
98
2.49
4.08
1.7
1.3
—
—
—
0
0
52
292
1.83
3.96
1.8
1.9
—
—
—
0
0
24
100
2.44
3.92
1.7
1.3
—
—
—
0
0
125
882
1.49
3.90
4.3
4.2
263.20
253.20
u/l
0.10
113
834
24
102
2.39
3.77
1.7
1.3
—
—
—
0
0
24
102
2.39
3.77
1.7
1.3
—
—
—
0
0
699
6543
1.48
3.76
5.8
5.4
5.96
5.98
mmol/l
0.18
614
5974
32
156
2.09
3.66
1.9
1.3
11.82
9.65
u/l
0.22
26
120
275
2260
1.33
3.49
1.8
1.8
20.86
20.38
nmol/l
0.18
212
1897
673
6283
1.41
3.40
6.4
5.4
1.89
1.94
mu/l
0.52
597
5755
47
270
1.79
3.36
1.6
1.7
—
—
—
0
0
173
1340
1.37
3.22
2.1
1.9
—
—
—
0
0
374
3232
1.29
3.21
2.7
2.5
76.95
77.89
nmol/l
0.28
310
2887
405
3538
1.29
3.19
15.9
15.5
1.26
1.28
inr
0.30
323
2945
386
3360
1.28
3.09
3.2
2.8
—
—
estimate
—
0
0
713
6769
1.43
2.87
6.5
6.0
2.63
2.66
mmol/l
0.36
626
6238
168
1322
1.34
2.81
1.9
1.8
1066.70
1178.03
nmol/l
0.70
105
998
378
3315
1.26
2.74
5.3
5.1
35.74
35.38
g/l
0.64
345
3108
672
6336
1.35
2.67
4.7
4.4
1.26
1.28
mmol/l
0.36
581
5778
276
2339
1.27
2.65
2.7
2.5
59.39
62.90
u/l
0.43
249
2173
426
3802
1.25
2.61
3.6
4.1
0.00
1.97
estimate
0.50
64
824
70
479
1.50
2.57
1.9
1.7
—
—
—
0
0
429
3837
1.25
2.56
3.6
4.1
0.07
0.40
estimate
0.40
59
768
46
286
1.64
2.54
3.5
4.1
25.10
25.07
mmol/l
0.02
38
266
274
2337
1.26
2.46
2.6
2.2
189.28
251.98
u/l
0.79
249
2216
237
1987
1.27
2.46
2.5
2.3
2.80
2.98
mg/l
0.63
187
1691
83
595
1.44
2.43
3.3
3.2
122.22
214.16
ng/l
3.97
72
547
699
6655
1.36
2.39
5.7
5.3
4.54
4.57
mmol/l
0.28
621
6162
568
5269
1.26
2.35
5.0
4.3
14.92
14.86
pmol/l
0.19
484
4799
752
7256
1.48
2.31
29.9
26.0
91.15
91.34
fl
0.56
743
7175
10
34
2.96
2.28
1.8
1.2
—
—
—
0
0
752
7258
1.47
2.28
30.3
26.5
40.17
40.17
%
0.01
743
7172
752
7258
1.47
2.28
29.9
26.1
4.48
4.46
e12/l
0.26
733
7096
752
7260
1.47
2.25
30.2
26.3
134.48
134.48
g/l
0.00
743
7176
31
179
1.76
2.25
1.1
1.3
—
—
—
0
0
160
1291
1.30
2.23
3.3
3.1
1.21
1.16
e6/l
0.08
77
711
431
3893
1.23
2.23
6.8
6.7
11.74
11.46
umol/l
0.14
405
3727
703
6714
1.35
2.23
19.9
17.2
22.85
25.09
mg/l
1.24
598
5619
280
2417
1.24
2.22
3.3
3.3
1653.88
1422.80
ng/l
0.45
233
2082
502
4608
1.23
2.22
3.4
3.4
44.89
50.60
u/l
1.00
456
4326
75
538
1.43
2.20
3.7
3.5
4.92
5.14
kpa
1.27
69
519
54
364
1.52
2.16
2.9
3.9
1.02
1.02
ratio
0.11
46
347
739
7121
1.41
2.14
26.2
22.7
79.85
79.49
umol/l
0.10
726
7041
29
167
1.76
2.14
1.4
1.4
—
—
—
0
0
721
6922
1.36
2.12
23.7
20.7
3.97
3.99
mmol/l
0.96
697
6784
734
7067
1.39
2.12
14.3
12.6
26.99
25.90
u/l
0.42
710
6861
35
214
1.66
2.10
1.8
1.3
—
—
—
0
0
194
1617
1.26
2.08
1.3
1.3
2.16
1.27
u/ml
0.36
36
432
297
2597
1.23
2.06
3.4
3.5
2.37
2.35
mmol/l
0.90
259
2345
416
3763
1.22
2.06
3.6
4.1
0.00
0.00
estimate
-0.00
61
805
36
223
1.64
2.06
1.6
1.3
—
—
—
0
0
693
6622
1.31
2.05
5.7
5.2
1.45
1.46
mmol/l
0.25
608
6089
44
288
1.56
2.02
2.4
2.3
11.08
10.69
g/l
0.17
31
255
105
812
1.34
1.98
3.1
4.5
7.96
26.51
ug/l
1.03
78
679
719
6913
1.34
1.98
23.4
20.5
139.68
139.69
mmol/l
0.03
698
6785
91
693
1.35
1.91
3.5
2.4
38.51
33.92
u/l
0.53
68
573
749
7254
1.41
1.91
30.0
26.1
248.07
246.49
e9/l
0.27
738
7112
366
3291
1.20
1.87
3.4
3.0
141.08
128.54
ug/l
0.26
325
3042
9
34
2.67
1.87
2.0
1.2
—
—
—
0
0
9
34
2.67
1.87
2.0
1.2
—
—
—
0
0
11
46
2.41
1.85
1.8
1.3
—
—
—
0
0
11
46
2.41
1.85
1.8
1.3
—
—
—
0
0
109
858
1.31
1.83
3.2
2.9
7.52
8.47
umol/l
0.20
97
778
76
569
1.37
1.78
1.5
1.5
—
—
—
0
0
29
177
1.66
1.78
1.6
1.6
317.59
296.34
mu/l
0.14
29
164
85
648
1.35
1.78
2.7
2.5
5.36
7.02
ug/l
0.58
68
574
670
6405
1.26
1.76
7.4
6.8
39.86
39.55
mmol/mol
0.39
595
5962
99
775
1.32
1.74
3.8
3.5
2.23
1.87
mmol/l
0.49
86
667
680
6517
1.26
1.71
19.0
16.7
78.33
78.71
ml/min/173m2
0.18
631
6070
62
452
1.40
1.71
3.7
3.5
1.66
1.93
mmol/l
0.23
44
335
47
326
1.47
1.69
1.1
1.1
—
—
—
0
0
85
654
1.33
1.68
3.7
3.0
66.50
66.74
g/l
0.10
68
599
6
19
3.17
1.66
1.8
1.6
—
—
—
0
0
14
69
2.05
1.65
1.6
1.2
4224.25
328587.27
e6/l
—
8
45
146
1210
1.25
1.64
3.3
3.2
3.35
2.18
e6/l
0.75
63
625
281
2491
1.20
1.63
6.1
5.7
3.99
2.73
ug/l
0.40
246
2231
16
84
1.92
1.60
1.3
1.3
—
—
—
0
0
27
167
1.64
1.60
2.3
1.9
203.37
220.94
pmol/l
0.40
27
158
123
1004
1.27
1.58
2.0
1.9
—
—
—
0
0
10
205
0.48
1.53
1.6
1.5
—
—
—
0
0
147
1232
1.24
1.50
2.7
2.5
2.35
2.30
g/l
0.49
130
1141
137
1143
1.24
1.46
2.7
2.5
23.34
22.36
%
0.40
123
1068
46
328
1.43
1.46
3.6
2.3
4.22
3.72
g/l
0.37
36
298
9
38
2.38
1.46
1.2
1.1
—
—
—
0
0
46
329
1.42
1.44
3.6
2.2
4.35
4.21
g/l
0.54
36
298
46
329
1.42
1.44
3.6
2.2
7.63
7.33
g/l
0.47
36
298
317
2871
1.17
1.39
4.5
4.1
36.46
92.57
ng/l
1.04
240
2148
123
1021
1.24
1.38
4.9
5.6
0.97
1.02
mmol/l
1.33
106
940
5
17
2.95
1.36
4.4
2.2
0.81
0.81
ug/l
—
5
17
13
68
1.93
1.34
1.2
1.2
—
—
—
0
0
237
2105
1.18
1.31
3.6
3.4
0.46
0.44
e6/l
0.03
164
1585
43
310
1.41
1.31
3.3
2.3
2.78
2.97
g/l
0.67
33
279
271
2435
1.17
1.30
3.6
3.5
48.24
95.05
e6/l
0.78
199
1895
209
1839
1.18
1.29
4.5
4.2
91.08
88.70
%
0.69
200
1811
11
55
2.01
1.27
1.2
1.2
—
—
—
0
0
17
100
1.71
1.24
1.2
1.2
—
—
—
0
0
178
1552
1.19
1.22
1.9
1.8
438.06
13119051.62
pmol/l
0.72
130
1273
7
145
0.48
1.21
1.1
2.5
8.04
8.54
pmol/l
—
7
145
74
589
1.28
1.20
3.0
2.4
12.70
13.41
nmol/l
0.28
64
528
49
368
1.35
1.19
1.5
1.9
1.41
1.49
g/l
0.29
41
329
177
1550
1.18
1.16
3.0
3.1
2.46
2.45
mmol/l
0.25
157
1395
104
866
1.23
1.15
2.6
2.3
101.27
122.15
ug/g
0.59
74
671
7
30
2.34
1.12
1.1
1.3
—
—
—
0
0
65
514
1.29
1.12
2.3
2.0
—
—
—
0
0
85
702
1.24
1.03
3.0
2.0
361.92
381.74
nmol/l
0.42
78
655
71
575
1.26
1.03
3.6
2.8
70.74
65.70
ml/min/173m2
0.60
38
259
280
2567
1.14
0.99
3.3
3.4
7.31
7.55
mmol/l
0.44
218
2139
5
23
2.18
0.98
2.6
3.1
0.64
0.59
mmol/l
—
5
23
0
29
0.00
0.98
0.0
1.0
—
—
—
0
0
31
226
1.39
0.94
1.5
1.4
259.50
286.55
ug/g
0.33
18
136
40
305
1.33
0.92
1.9
2.2
43.47
38.57
u/l
0.68
30
268
23
159
1.46
0.92
2.2
1.6
—
—
—
0
0
150
1323
1.16
0.91
2.8
2.5
13.29
12.75
umol/l
0.47
131
1233
33
245
1.36
0.90
1.5
1.3
—
—
—
0
0
10
56
1.80
0.88
1.1
1.2
—
—
—
0
0
307
2850
1.12
0.87
3.4
4.1
0.04
0.03
estimate
0.04
54
665
144
1275
1.16
0.84
3.5
3.2
0.82
0.82
mmol/l
0.11
130
1196
10
57
1.76
0.84
1.2
1.2
—
—
—
0
0
10
57
1.76
0.84
1.2
1.2
—
—
—
0
0
84
712
1.20
0.82
2.1
2.4
0.22
0.21
g/l
0.51
78
663
71
592
1.22
0.82
3.3
4.0
79.33
88.08
ng/l
0.51
58
528
6
33
1.82
0.79
1.2
1.2
—
—
—
0
0
37
287
1.30
0.78
3.0
2.5
2.07
0.93
g/l
0.49
27
252
123
1084
1.16
0.77
1.5
1.5
—
—
—
0
0
68
569
1.21
0.77
2.4
2.1
—
—
—
0
0
27
200
1.36
0.77
2.0
1.5
6743.71
15549.73
e6/l
1.22
21
139
9
54
1.67
0.74
1.0
1.2
10.22
12.55
u/l
—
9
49
56
462
1.23
0.73
3.0
2.5
48.60
22.19
au/ml
—
5
32
257
2384
1.11
0.73
3.7
3.3
50.01
33.33
u/l
0.36
234
2256
15
100
1.51
0.73
1.1
1.3
0.68
0.62
nmol/l
0.27
15
93
183
1665
1.13
0.73
3.6
4.3
1.02
1.02
kg/l
0.14
129
1129
14
92
1.53
0.72
1.0
1.1
—
—
—
0
0
13
84
1.56
0.72
1.0
1.2
137.63
116.51
%
—
8
77
210
1930
1.12
0.70
2.9
2.9
339.48
348.17
umol/l
0.55
176
1684
5
26
1.93
0.70
2.6
3.6
28.60
33.52
umol/l
—
5
20
7
43
1.63
0.67
5.4
2.4
—
—
—
0
0
32
250
1.29
0.66
2.5
3.5
1.61
2.68
ratio
1.12
26
148
51
422
1.22
0.66
1.6
1.3
63.00
47.68
au/ml
—
7
29
35
277
1.28
0.66
2.6
2.9
—
—
—
0
0
5
28
1.79
0.66
2.6
1.6
—
—
—
0
0
5
28
1.79
0.66
2.6
1.6
—
—
—
0
0
5
28
1.79
0.66
4.2
2.0
38.82
40.77
g/l
—
5
28
270
2525
1.10
0.65
4.1
4.1
17.44
9.42
mg/mmol
0.49
164
1565
7
44
1.60
0.65
1.3
1.4
209.59
155.69
pmol/l
—
7
44
104
920
1.15
0.64
6.3
7.1
1.35
1.09
mmol/l
0.30
85
753
15
212
0.70
0.64
1.6
1.2
—
—
—
0
0
5
29
1.73
0.64
2.6
1.7
—
—
—
0
0
10
63
1.59
0.62
1.2
1.1
—
—
—
0
0
45
371
1.23
0.61
2.6
3.4
25.41
25.10
mmol/l
0.23
45
360
5
30
1.67
0.61
1.0
1.1
—
—
—
0
0
161
1471
1.12
0.61
5.5
4.1
78.25
327.39
ng/l
4.14
127
1180
0
20
0.00
0.60
0.0
1.0
—
28.94
—
0
20
64
548
1.18
0.60
2.1
1.6
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
27
211
1.29
0.57
1.5
1.3
2.62
5.95
u/ml
—
5
33
174
1602
1.11
0.57
1.8
1.7
1.03
1.30
mg/l
0.72
133
1248
34
274
1.25
0.57
1.8
2.1
—
—
—
0
0
6
37
1.63
0.55
1.2
1.1
—
—
—
0
0
51
594
0.85
0.51
3.8
3.6
1.21
1.23
mmol/l
0.97
44
509
68
774
0.87
0.51
2.9
3.5
—
—
—
0
0
105
947
1.12
0.51
2.2
1.9
—
—
—
0
0
184
1714
1.09
0.49
2.8
2.8
4.16
5.68
e6/l
1.24
167
1569
22
172
1.29
0.48
1.2
1.5
—
—
—
0
0
22
172
1.29
0.48
3.9
3.6
0.79
0.86
nmol/l
0.24
16
145
39
328
1.20
0.47
3.6
3.6
424.97
1461.44
u/ml
0.99
30
283
14
103
1.37
0.45
1.1
1.1
1.10
1.43
u/ml
—
9
51
12
86
1.40
0.44
1.8
1.7
—
—
—
0
0
26
211
1.24
0.44
1.6
1.6
—
—
—
0
0
26
211
1.24
0.44
1.9
1.6
—
—
—
0
0
13
95
1.37
0.44
1.4
1.2
1.20
4.44
u/ml
—
5
39
103
938
1.11
0.44
6.4
6.9
5.16
5.13
kpa
0.15
95
900
103
939
1.11
0.43
6.4
6.9
12.55
11.94
kpa
0.75
95
904
22
177
1.25
0.40
1.2
1.3
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
34
1.47
0.40
1.2
1.2
—
—
—
0
0
28
232
1.21
0.40
1.7
2.0
—
—
—
0
0
25
303
0.82
0.40
2.1
1.3
—
—
—
0
0
67
599
1.13
0.39
2.0
2.1
3.55
3.49
ratio
0.15
49
479
217
2056
1.08
0.39
3.1
3.6
0.00
0.05
estimate
0.60
50
642
11
80
1.38
0.38
1.8
1.7
—
—
—
0
0
6
43
1.40
0.35
1.2
1.4
2.34
3.75
ug/l
—
6
33
6
44
1.37
0.34
2.0
1.2
—
—
—
0
0
6
44
1.37
0.34
1.0
1.0
—
—
—
0
0
39
340
1.15
0.34
3.7
3.4
19.12
100.21
u/ml
1.50
39
326
6
46
1.31
0.33
2.0
1.8
—
—
—
0
0
29
248
1.18
0.32
1.8
1.3
25.54
28.06
iu/l
0.15
24
210
7
98
0.71
0.31
1.1
1.6
—
—
—
0
0
17
138
1.24
0.30
1.2
1.3
—
131.11
—
0
9
16
195
0.82
0.29
1.2
1.2
1.00
0.89
g/l
0.70
16
195
26
302
0.86
0.29
1.4
1.5
0.20
0.31
mg/l
1.05
11
140
9
118
0.76
0.27
1.3
1.4
—
—
—
0
0
8
66
1.21
0.26
1.5
1.0
—
—
—
0
0
8
66
1.21
0.26
1.1
1.5
—
30.33
—
0
6
21
246
0.85
0.26
1.4
2.0
7.37
4.13
mg/l
0.38
12
198
23
197
1.17
0.26
1.6
1.6
—
—
—
0
0
49
444
1.11
0.26
1.7
1.8
3.40
3.47
mmol/l
0.16
34
328
9
75
1.20
0.25
4.4
2.4
—
—
—
0
0
13
159
0.81
0.25
1.2
1.3
548.86
851.73
e6/l
—
7
120
23
199
1.16
0.23
1.3
1.6
—
—
—
0
0
12
97
1.24
0.23
1.2
1.0
—
—
—
0
0
7
91
0.77
0.22
1.1
1.1
—
1.67
—
0
17
7
92
0.76
0.22
2.3
3.7
—
—
—
0
0
5
40
1.25
0.22
2.6
1.6
—
—
—
0
0
5
40
1.25
0.22
2.6
1.6
—
—
—
0
0
5
40
1.25
0.22
2.6
1.6
—
—
—
0
0
5
40
1.25
0.22
2.6
1.6
—
—
—
0
0
34
305
1.12
0.22
1.7
2.0
10.13
7.88
iu/ml
—
10
73
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
7.5
—
10.58
—
0
12
0
13
0.00
0.21
0.0
1.2
—
33.16
—
0
8
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
20
229
0.87
0.20
2.9
2.5
0.27
0.37
iu/ml
0.71
12
127
13
108
1.21
0.20
1.2
1.5
30.72
32.13
g/l
0.18
13
99
11
132
0.83
0.18
1.1
1.3
205.00
286.17
u/ml
—
6
70
29
263
1.11
0.16
1.5
1.6
41.60
9.34
u/ml
—
5
48
143
1482
0.96
0.16
3.5
3.2
0.79
0.78
ug/l
0.03
81
973
8
69
1.16
0.16
2.1
1.4
—
—
—
0
0
95
908
1.05
0.16
1.6
1.4
—
—
—
0
0
45
419
1.08
0.15
3.2
3.9
48.46
47.05
%
0.13
45
412
124
1196
1.04
0.14
1.3
1.3
6.33
12.44
u/ml
0.71
41
438
17
150
1.14
0.14
2.9
2.5
16.05
16.25
%
0.12
17
145
16
181
0.88
0.14
1.2
1.2
1.51
1.54
g/l
0.16
16
181
37
398
0.93
0.14
1.3
1.4
—
—
—
0
0
17
191
0.89
0.14
1.3
1.2
—
—
—
0
0
17
191
0.89
0.14
1.3
1.2
—
—
—
0
0
12
137
0.87
0.12
1.2
1.3
—
—
—
0
0
13
147
0.88
0.11
1.4
1.5
—
—
—
0
0
22
201
1.10
0.11
3.1
3.1
1.33
1.84
index
0.19
12
109
14
157
0.89
0.11
1.1
1.2
28.38
50.09
e6/l
—
8
114
10
86
1.16
0.11
1.2
1.1
1.22
2.67
eliau/ml
—
5
30
10
115
0.87
0.10
1.7
1.7
—
—
—
0
0
204
2000
1.03
0.10
5.1
4.6
21.62
21.68
%
0.02
85
979
5
44
1.14
0.10
1.2
1.6
104.80
80.93
umol/l
—
5
44
295
2909
1.02
0.09
2.1
1.9
1.28
1.34
mmol/l
0.91
231
2428
5
46
1.09
0.09
1.8
1.5
—
—
—
0
0
42
399
1.06
0.09
4.8
3.7
4.43
4.54
pmol/l
0.33
35
350
5
48
1.04
0.09
1.0
1.1
368.40
246.49
mg/l
—
5
39
19
175
1.09
0.08
1.4
1.5
—
—
—
0
0
6
58
1.03
0.08
1.0
1.2
—
—
—
0
0
17
185
0.92
0.08
2.2
2.4
51.89
88.33
ug/min
—
9
110
5
64
0.78
0.08
7.6
2.4
14.22
13.17
%
—
5
64
7
65
1.08
0.08
1.0
1.6
—
—
—
0
0
6
73
0.82
0.07
1.0
1.1
—
—
—
0
0
6
75
0.80
0.07
1.0
1.1
—
—
—
0
0
36
343
1.05
0.07
1.9
1.8
0.69
2.46
ug/l
1.27
28
304
8
77
1.04
0.07
1.9
1.2
—
—
—
0
0
7
85
0.82
0.07
1.1
1.2
—
—
—
0
0
19
200
0.95
0.04
1.5
1.4
—
—
—
0
0
131
1294
1.01
0.03
1.3
1.3
17.33
35.12
iu/ml
4.37
39
402
213
2115
1.01
0.03
3.5
4.2
0.00
0.01
estimate
0.96
54
750
13
122
1.07
0.02
1.3
1.6
—
—
—
0
0
45
457
0.98
0.01
1.2
1.2
136.72
124.19
u/ml
0.04
11
183
20
206
0.97
0.00
2.3
2.3
3.48
3.56
g/l
0.14
20
200
26
254
1.02
0.00
2.8
2.4
0.00
0.02
g/l
0.50
21
229
46
466
0.99
0.00
1.5
1.3
125.06
298.24
u/ml
1.42
40
428
19
185
1.03
0.00
1.4
1.4
243.42
245.09
miu/ml
—
9
84
14
144
0.97
0.00
1.6
1.3
—
—
—
0
0
14
144
0.97
0.00
1.6
1.3
—
—
—
0
0
15
153
0.98
0.00
1.4
1.5
—
—
—
0
0
51
505
1.01
0.00
6.9
6.3
25.27
24.50
mmol/l
0.76
46
482
25
247
1.01
0.00
1.8
2.4
0.00
0.00
g/l
-0.00
20
216
13
132
0.98
0.00
1.8
1.8
—
—
—
0
0
79
791
1.00
0.00
1.5
1.8
1.40
1.52
%
0.85
61
691
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
7
75
0.93
0.00
2.4
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
7
77
0.91
-0.00
2.4
1.5
—
—
—
0
0
8
87
0.92
-0.00
1.6
1.6
55.90
59.97
ug/l
—
8
71
0
5
0.00
-0.00
0.0
1.2
—
13.00
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
77
0.91
-0.00
2.4
1.5
—
—
—
0
0
6
60
1.00
-0.00
1.2
1.2
100.83
100.70
pmol/l
—
6
60
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
73
0.96
-0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
-0.00
1.0
1.7
—
—
—
0
0
6
60
1.00
-0.00
1.0
1.1
—
—
—
0
0
7
77
0.91
-0.00
2.4
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
8
80
1.00
-0.00
1.5
1.5
—
—
—
0
0
9
91
0.99
-0.00
1.1
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_LIP and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_LIP | 1.028 [0.9, 1.17] | 0.68 |
| Birth year | 0.996 [0.99, 1.0] | 0.394 |
During the follow-up period (1.1.1998 — 31.12.2019), 393 out of 2264 females with CD2_BENIGN_LIP died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_LIP | 1.101 [0.97, 1.24] | 0.126 |
| Birth year | 0.988 [0.98, 1.0] | 0.021 |
During the follow-up period (1.1.1998 — 31.12.2019), 600 out of 2302 males with CD2_BENIGN_LIP died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_LIP.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.092% | 0.172% |
| 5 | 0.595% | 1.164% |
| 10 | 1.653% | 3.209% |
| 15 | 3.195% | 6.197% |
| 20 | 5.499% | 10.545% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_LIP – Benign neoplasm: Lip
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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