Melanocytic naevi of lip

CD2_BENIGN_MELANOCYTIC_LIP

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D22.0&
  • Hospital discharge: ICD-9 2160A
  • Cause of death: ICD-10 D22.0&
  • Cause of death: ICD-9 2160A

2 out of 7 registries used, show all original rules.

348

4. Check minimum number of events

None

348

5. Include endpoints

None

348

6. Filter based on genotype QC (FinnGen only)

313

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D22
Name in latin
Naevus melanocyticus (cutis) labii (oris)

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2143 1358 781
Only index persons 2030 1302 728
Unadjusted period prevalence (%)
Whole population 0.03 0.04 0.02
Only index persons 0.04 0.05 0.03
Median age at first event (years)
Whole population 39.45 40.56 37.57
Only index persons 38.35 40.23 35.00

-FinnGen-

Key figures

All Female Male
Number of individuals 313 235 78
Unadjusted period prevalence (%) 0.07 0.08 0.04
Median age at first event (years) 44.31 42.72 49.12

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
322
Matched controls
3220
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D22.0
ICD-10 Finland
Melanocytic naevi of lip
4503599627370496.0
307.7
294
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
7.9
52.3
84
137
2160A
ICD-9 Finland
Benign neoplasm of skin, Skin of lip[HUULEN IHON BENIGNI KASVAIN,NAEVUS PIGMENTOSUS]
+∞
29.6
28
*
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
6.1
28.6
55
105
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
5.5
22.6
48
100
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
5.5
22.3
47
97
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.5
19.9
54
138
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
7.5
16.3
24
34
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
5.9
13.6
25
45
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
9.2
12.3
25
29
EAA10
NOMESCO Finland
Excision of lesion of lip
17.4
10.0
15
9
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
7.7
9.4
21
29
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.3
8.3
33
109
9733
FHL
Excision of skin change in operating room or anesthesia
7.7
7.8
17
23
XQ848
NOMESCO Finland
Dermatological photography
4.5
7.0
17
39
SPAT1141
SPAT
Excision of skin or mucous membrane lesion
3.7
6.8
22
63
S82
ICPC
Naevus/mole
2.2
6.6
60
301
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
6.5
6.2
15
24

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
161
1164
1.77
5.88
2.6
2.1
—
—
—
0
0
121
890
1.58
3.67
3.3
3.2
6.93
7.45
mmol/l
0.55
98
752
110
833
1.49
2.78
4.1
4.0
8.06
8.18
mg/mmol
0.01
66
499
107
810
1.48
2.69
3.5
3.3
32.48
44.87
mg/l
0.51
65
509
142
1168
1.39
2.18
2.2
2.1
97.84
96.22
pmol/l
0.15
68
601
7
19
3.74
2.16
1.0
1.0
—
—
—
0
0
97
1221
0.71
2.16
3.3
3.0
—
—
—
0
0
45
302
1.57
1.96
2.3
1.6
—
—
—
0
0
33
205
1.68
1.95
1.2
1.2
—
—
—
0
0
116
937
1.37
1.94
6.0
5.6
—
—
—
0
0
6
16
3.80
1.94
3.0
2.8
26.75
15.61
mu/l
—
6
16
47
323
1.53
1.85
1.7
2.7
6.77
7.23
umol/l
0.12
42
278
5
12
4.21
1.83
1.2
1.1
—
—
—
0
0
176
1528
1.33
1.80
7.1
6.2
0.22
0.18
e9/l
1.44
160
1336
293
2771
1.64
1.77
18.7
16.5
139.48
139.73
mmol/l
0.89
287
2714
38
253
1.57
1.73
1.2
1.2
—
—
—
0
0
292
2772
1.57
1.57
19.4
16.7
3.95
3.95
mmol/l
0.03
287
2711
57
422
1.43
1.57
3.3
3.0
2.10
3.03
e6/l
0.48
24
194
17
93
1.87
1.54
1.2
1.3
—
—
—
0
0
51
372
1.44
1.52
1.5
1.2
—
—
—
0
0
21
124
1.74
1.51
3.4
2.2
—
—
—
0
0
168
1473
1.29
1.50
7.2
5.9
0.53
0.55
e9/l
0.69
148
1268
168
1477
1.29
1.45
7.2
6.0
0.04
0.04
e9/l
0.24
149
1269
5
16
3.16
1.44
1.0
1.1
—
—
—
0
0
56
424
1.39
1.37
1.6
1.7
1343.89
1233.40
nmol/l
0.23
47
312
5
17
2.97
1.36
1.8
2.9
—
—
—
0
0
185
1657
1.27
1.34
10.6
9.5
4.07
4.04
e9/l
0.09
161
1448
5
18
2.80
1.29
2.0
5.4
6.64
8.68
mmol/l
—
5
18
108
910
1.28
1.27
2.1
2.4
52.91
66.87
u/l
1.23
102
851
20
126
1.63
1.17
1.5
1.5
196.91
241.18
miu/ml
0.28
11
68
168
1503
1.25
1.17
7.3
6.0
2.00
1.99
e9/l
0.02
156
1330
87
722
1.28
1.15
2.5
2.1
2.64
2.88
mg/l
0.49
78
625
12
65
1.88
1.15
1.6
2.9
1.25
2.87
ratio
—
7
39
169
1515
1.24
1.15
5.7
6.0
11.91
10.64
umol/l
0.61
163
1449
45
339
1.38
1.15
2.1
1.8
—
—
—
0
0
231
2150
1.26
1.10
8.4
7.8
76.28
77.59
u/l
0.17
218
2047
40
298
1.39
1.09
3.6
4.0
2.15
46.14
ug/l
0.97
34
242
158
1412
1.23
1.09
6.8
6.5
1.22
1.21
mmol/l
0.44
140
1206
80
662
1.28
1.08
3.5
3.8
—
0.29
—
0
7
146
1298
1.23
1.04
2.6
2.6
80.25
77.43
nmol/l
0.76
134
1192
103
887
1.24
0.99
3.5
2.8
—
—
—
0
0
5
23
2.19
0.98
1.4
1.1
—
—
—
0
0
21
141
1.52
0.97
2.5
1.8
1.73
5.04
iu/ml
—
6
35
26
183
1.46
0.97
1.2
1.3
27.57
26.46
iu/l
0.05
26
154
19
125
1.55
0.96
1.4
1.2
—
—
—
0
0
71
589
1.26
0.94
1.3
1.3
1.30
12.57
u/ml
3.84
34
234
13
78
1.69
0.93
4.0
3.1
0.83
2.05
index
—
6
43
300
2912
1.44
0.88
13.3
11.5
25.39
25.22
u/l
0.07
293
2848
270
2583
1.28
0.87
6.6
6.0
38.70
38.73
mmol/mol
0.02
252
2451
6
31
1.95
0.85
1.2
1.1
—
—
—
0
0
11
177
0.61
0.84
2.0
1.7
—
—
—
0
0
73
856
0.81
0.84
4.3
4.0
0.00
0.01
estimate
0.50
27
328
74
626
1.24
0.83
1.3
1.4
35.70
28.56
iu/ml
0.16
22
192
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
8
48
1.68
0.79
1.3
1.1
—
—
—
0
0
0
26
0.00
0.79
0.0
1.6
—
34.00
—
0
26
288
2786
1.32
0.78
16.7
14.4
20.23
21.53
mg/l
0.32
228
2271
15
99
1.54
0.77
1.2
1.3
—
—
—
0
0
241
2289
1.21
0.76
5.4
4.6
14.67
14.65
pmol/l
0.07
225
2127
149
1361
1.18
0.73
7.5
6.0
0.69
0.69
%
0.01
139
1268
275
2651
1.26
0.72
5.3
4.8
5.70
5.84
mmol/l
1.53
257
2461
15
102
1.49
0.69
1.3
1.9
—
—
—
0
0
160
1476
1.17
0.68
3.8
3.0
98.80
93.59
ug/l
0.17
153
1391
298
2905
1.35
0.68
21.0
18.4
76.47
72.87
umol/l
0.74
293
2871
31
242
1.31
0.67
1.4
2.5
0.23
0.22
g/l
0.50
31
227
47
388
1.25
0.67
1.2
1.2
—
—
—
0
0
5
28
1.80
0.66
1.2
1.1
—
—
—
0
0
45
370
1.25
0.66
2.4
2.1
—
—
—
0
0
54
454
1.23
0.65
1.6
1.4
236.92
512.14
titre
2.41
13
112
5
29
1.74
0.64
1.2
1.0
—
—
titre
—
0
0
61
521
1.21
0.64
3.7
3.3
306.56
193.53
ng/l
0.29
43
365
30
236
1.30
0.62
1.5
1.4
—
—
—
0
0
148
1365
1.16
0.62
7.5
6.0
8.28
8.59
%
0.76
139
1284
148
1365
1.16
0.62
7.5
5.9
3.25
2.78
%
1.24
138
1282
148
1366
1.15
0.61
7.3
5.9
57.80
56.93
%
0.43
140
1303
78
883
0.85
0.61
1.6
1.5
—
—
—
0
0
63
542
1.20
0.61
1.8
1.8
476.91
26681573.39
pmol/l
0.78
55
461
0
20
0.00
0.60
0.0
1.1
—
468460.71
—
0
14
16
114
1.42
0.60
1.3
1.5
—
15.90
—
0
6
0
22
0.00
0.59
0.0
1.0
—
313.13
—
0
15
13
89
1.48
0.59
1.2
1.2
—
—
—
0
0
11
161
0.67
0.58
1.2
1.1
—
—
—
0
0
18
132
1.39
0.58
1.3
1.5
—
—
—
0
0
6
35
1.73
0.58
1.0
1.3
—
—
nmol/l
—
0
0
19
141
1.37
0.58
1.3
1.5
—
—
—
0
0
19
141
1.37
0.58
1.3
1.5
—
—
—
0
0
75
661
1.18
0.56
3.9
3.8
1.02
1.02
kg/l
0.03
49
432
146
1353
1.14
0.56
3.2
2.6
—
—
estimate
—
0
0
108
984
1.15
0.53
3.3
3.2
2.37
2.36
mmol/l
0.35
99
907
14
100
1.42
0.52
1.6
1.4
—
—
—
0
0
95
858
1.15
0.52
8.0
6.6
—
—
—
0
0
19
144
1.34
0.52
3.8
7.1
—
—
—
0
0
93
1025
0.87
0.51
3.2
3.6
24.30
64.34
ng/l
0.58
59
675
295
2887
1.26
0.51
16.9
12.7
—
—
—
0
0
17
127
1.36
0.50
1.8
1.5
54.45
57.31
ug/l
0.10
12
110
273
2653
1.19
0.50
6.7
5.6
1.86
1.83
mu/l
0.21
260
2479
19
244
0.76
0.49
1.7
2.3
5.70
6.16
ph
—
10
158
87
785
1.15
0.49
3.8
3.1
0.66
0.40
e6/l
0.66
59
572
88
796
1.15
0.47
1.6
1.7
21.30
21.22
nmol/l
0.02
78
672
137
1276
1.13
0.47
6.0
6.0
1.22
1.22
mmol/l
0.02
127
1179
75
671
1.15
0.47
2.8
2.6
321.09
326.82
umol/l
0.19
65
600
8
117
0.68
0.46
1.5
2.0
—
—
—
0
0
34
284
1.22
0.46
2.3
2.3
31.68
29.22
u/l
0.40
28
240
30
248
1.23
0.45
3.1
3.0
0.73
0.78
ug/l
0.15
18
150
127
1182
1.12
0.44
1.9
1.9
1.39
1.34
mmol/l
0.18
108
1017
62
550
1.16
0.44
2.6
2.8
2.42
2.45
mmol/l
0.98
50
499
15
113
1.34
0.43
1.3
1.4
—
—
—
0
0
18
140
1.30
0.43
1.3
1.5
—
—
—
0
0
31
259
1.22
0.42
3.5
2.7
7.40
7.38
ph
0.74
18
146
5
32
1.57
0.42
4.0
2.3
102.00
106.03
mmol/l
—
5
32
5
32
1.57
0.42
4.0
2.3
3.96
3.98
mmol/l
—
5
32
5
32
1.57
0.42
4.0
2.3
1.23
1.19
mmol/l
—
5
32
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
0.00
—
0
15
24
196
1.24
0.40
2.8
2.8
65.89
69.43
e9/l
0.28
16
144
148
1396
1.11
0.40
7.6
6.0
27.76
28.56
%
0.44
141
1328
43
374
1.17
0.39
3.3
2.9
4.41
4.95
e9/l
0.27
38
332
18
142
1.28
0.39
1.3
1.5
—
—
—
0
0
26
216
1.22
0.38
3.3
2.4
5.52
4.42
kpa
1.25
26
211
8
114
0.69
0.38
1.0
1.1
1.61
1.57
g/l
—
8
114
6
42
1.44
0.35
2.7
1.6
—
—
—
0
0
131
1235
1.10
0.35
3.7
3.5
6.46
6.23
ph
1.33
73
704
13
100
1.31
0.34
1.7
1.4
1.15
1.31
mm
—
8
76
161
1536
1.10
0.33
3.9
3.8
0.00
0.00
estimate
-0.00
29
345
76
699
1.11
0.32
3.9
3.6
92.54
92.90
%
0.04
76
688
21
251
0.83
0.32
13.6
4.5
0.00
0.37
%
—
8
59
34
296
1.17
0.32
4.8
8.9
1.70
1.03
mmol/l
0.60
26
252
162
1549
1.09
0.31
3.9
3.9
0.00
4.59
estimate
0.50
30
354
139
1320
1.09
0.31
13.7
10.9
0.00
0.00
e9/l
0.67
110
1087
7
54
1.30
0.30
1.1
1.0
—
—
—
0
0
61
666
0.90
0.30
2.3
2.0
—
—
—
0
0
43
384
1.14
0.29
1.8
1.6
—
—
—
0
0
21
248
0.84
0.29
2.9
3.7
—
—
—
0
0
7
57
1.23
0.29
1.3
1.8
—
—
—
0
0
85
792
1.10
0.29
1.4
1.3
0.63
1.80
u/ml
1.23
22
218
13
103
1.27
0.28
1.8
1.5
—
—
—
0
0
9
118
0.76
0.28
1.0
1.2
0.86
0.92
g/l
—
9
118
35
393
0.88
0.27
1.9
1.8
—
—
—
0
0
17
141
1.22
0.26
3.5
2.1
0.66
0.62
%
0.15
17
141
113
1071
1.08
0.26
4.5
4.0
97.81
66.53
e6/l
0.27
75
738
5
73
0.68
0.26
5.2
2.7
57.12
59.31
%
—
5
73
75
698
1.10
0.26
1.5
1.3
2.28
2.26
g/l
0.03
43
424
22
255
0.85
0.25
12.4
4.2
0.60
0.81
%
—
10
74
89
837
1.09
0.25
2.2
2.1
209.56
235.30
u/l
0.09
84
802
11
87
1.27
0.24
1.5
3.5
259.17
238.33
mg/l
—
6
30
5
38
1.32
0.23
1.6
1.2
—
—
—
0
0
40
363
1.12
0.22
5.3
6.3
101.72
104.39
mmol/l
1.58
40
363
33
296
1.13
0.22
4.6
8.9
7.42
7.41
ph
0.08
17
168
23
262
0.87
0.22
1.9
1.9
3.68
3.45
mmol/l
0.32
14
200
5
41
1.22
0.22
3.6
2.9
—
—
—
0
0
97
921
1.08
0.21
2.2
2.2
—
—
—
0
0
5
42
1.19
0.21
3.6
2.4
—
—
—
0
0
167
1617
1.07
0.21
3.9
4.8
6.86
6.50
mmol/l
1.30
151
1504
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
73
686
1.08
0.21
6.8
4.2
—
—
—
0
0
5
43
1.17
0.21
1.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
23.68
—
0
13
96
913
1.07
0.20
3.9
3.3
47.86
109.45
e6/l
0.39
70
697
0
14
0.00
0.20
0.0
1.3
—
184.74
—
0
14
20
174
1.16
0.20
1.3
2.4
—
—
—
0
0
26
291
0.88
0.20
1.5
1.4
—
—
—
0
0
6
50
1.20
0.20
1.2
1.0
—
—
—
0
0
201
1962
1.07
0.19
3.2
3.2
45.39
40.83
u/l
0.38
192
1871
161
1561
1.06
0.19
4.0
3.9
0.00
0.02
estimate
0.79
28
328
18
156
1.16
0.19
1.7
2.2
12016.74
2100.89
u/l
—
5
59
6
53
1.13
0.19
1.3
1.3
—
—
—
0
0
282
2787
1.10
0.18
6.2
5.5
2.71
2.77
mmol/l
0.60
265
2614
62
658
0.93
0.18
1.8
1.7
1.04
1.11
mg/l
0.10
42
511
7
61
1.15
0.17
1.0
1.1
—
—
—
0
0
7
61
1.15
0.17
1.0
1.1
—
—
—
0
0
127
1226
1.06
0.17
16.1
11.7
1.26
1.19
inr
0.70
98
1009
10
82
1.23
0.17
2.3
2.6
—
—
—
0
0
58
545
1.08
0.17
4.4
2.7
535.85
514.95
mosm/kgh2o
0.28
46
479
5
68
0.73
0.17
1.0
1.5
—
—
—
0
0
8
68
1.18
0.16
9.9
3.8
—
—
—
0
0
6
76
0.79
0.16
9.3
3.1
7.41
7.42
ph
—
6
76
278
2749
1.08
0.15
5.3
4.8
1.53
1.52
mmol/l
0.15
262
2565
9
79
1.14
0.15
10.7
9.7
—
—
—
0
0
263
2597
1.07
0.15
4.5
4.1
1.33
1.25
mmol/l
0.42
243
2408
7
88
0.79
0.14
1.0
1.2
9.70
12.32
u/l
—
7
69
18
160
1.13
0.14
1.0
1.1
—
—
—
0
0
9
110
0.81
0.13
1.7
1.8
20.11
20.62
s
—
9
95
19
172
1.11
0.11
1.2
1.2
—
—
—
0
0
39
367
1.07
0.11
1.6
1.4
—
—
—
0
0
22
239
0.91
0.11
12.4
4.4
0.00
0.15
%
—
10
59
24
224
1.08
0.08
3.6
4.1
7.25
7.35
ph
0.37
17
158
5
62
0.80
0.08
1.8
2.4
8.10
8.22
kpa
—
5
62
5
62
0.80
0.08
1.2
1.3
—
—
—
0
0
28
297
0.94
0.08
1.6
1.4
—
—
—
0
0
5
65
0.77
0.08
1.0
2.0
—
—
—
0
0
16
174
0.92
0.08
4.7
6.6
24.74
24.95
mmol/l
0.09
16
174
6
72
0.83
0.07
1.0
1.2
—
—
—
0
0
23
244
0.94
0.06
11.4
4.1
0.60
0.73
%
—
10
66
11
99
1.12
0.06
1.1
1.1
—
—
—
0
0
11
99
1.12
0.06
1.5
2.9
—
—
—
0
0
24
253
0.94
0.05
1.9
1.5
—
—
—
0
0
22
208
1.06
0.05
2.8
3.0
21.68
41.16
u/ml
1.48
22
200
16
171
0.93
0.05
1.1
1.1
—
95.17
—
0
6
277
2757
1.03
0.04
5.5
4.9
4.72
4.73
mmol/l
0.05
265
2588
13
121
1.08
0.04
5.2
3.8
36.70
36.91
°c
0.38
13
121
14
148
0.94
0.02
1.7
2.9
7.44
7.42
ph
—
9
120
40
409
0.97
0.02
1.9
2.4
161.85
110.75
ug/g
0.26
27
317
58
571
1.02
0.02
2.0
1.7
—
—
—
0
0
36
353
1.02
0.01
1.4
1.3
—
—
—
0
0
71
717
0.99
0.01
7.2
4.9
—
—
—
0
0
22
226
0.97
0.00
6.5
7.4
—
—
—
0
0
63
636
0.99
0.00
3.0
2.7
5.31
7.57
e6/l
0.71
53
582
38
382
0.99
0.00
1.4
1.5
—
—
—
0
0
10
99
1.01
0.00
1.3
1.3
—
2.98
—
0
13
118
1181
1.00
0.00
4.1
3.6
0.00
0.02
estimate
0.96
23
291
25
247
1.01
0.00
1.1
1.2
64.95
175.86
u/ml
3.10
11
102
12
124
0.97
0.00
1.6
2.0
—
—
—
0
0
90
895
1.01
0.00
5.2
3.7
7.40
7.40
ph
0.03
70
626
89
895
0.99
0.00
3.4
3.2
0.00
0.00
estimate
0.50
25
282
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
6.67
—
0
5
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
57.00
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
53.33
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1.91
—
0
5
5
54
0.92
-0.00
9.0
3.0
8.38
9.34
pmol/l
—
5
54
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
7
74
0.94
-0.00
1.6
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
81
0.99
-0.00
2.6
2.5
1.24
1.40
mg/l
—
8
74
0
6
0.00
-0.00
0.0
1.0
—
31.08
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.2
—
12.00
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
82
0.97
-0.00
2.5
2.6
25.39
24.44
mmol/l
—
8
82
9
90
1.00
-0.00
1.2
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
15.10
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
41.40
—
0
5
7
69
1.01
-0.00
1.1
1.1
—
—
—
0
0
5
56
0.89
-0.00
3.6
2.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
1.19
—
0
7
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
1.39
—
0
7

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_MELANOCYTIC_LIP and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_LIP 0.855 [0.68, 1.07] 0.173
Birth year 1.0 [0.99, 1.01] 0.977

During the follow-up period (1.1.1998 — 31.12.2019), 98 out of 1211 females with CD2_BENIGN_MELANOCYTIC_LIP died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_LIP 1.024 [0.79, 1.32] 0.855
Birth year 0.988 [0.98, 1.0] 0.015

During the follow-up period (1.1.1998 — 31.12.2019), 99 out of 689 males with CD2_BENIGN_MELANOCYTIC_LIP died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_MELANOCYTIC_LIP.

N-year risk Females Males
1 0.102% 0.184%
5 0.639% 1.242%
10 1.545% 3.197%
15 2.804% 5.88%
20 4.939% 10.045%

Relationships between endpoints

Index endpoint: CD2_BENIGN_MELANOCYTIC_LIP – Melanocytic naevi of lip

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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