Atrial septal defect

Q17_ASD

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q21.1
  • Hospital discharge: ICD-9 7455A|7456A
  • Hospital discharge: excluded ICD-10 Q20|Q2111|Q2[2-5]|Q26[0-1]|Q26[5-9]
  • Cause of death: ICD-10 Q21.1
  • Cause of death: ICD-9 7455A|7456A
  • Cause of death: excluded ICD-10 Q20|Q2111|Q2[2-5]|Q26[0-1]|Q26[5-9]
  • Operations: NOMESCO codes ^FFC00|^FFC02|^FFC22|^FFC50|^FFC96

3 out of 7 registries used, show all original rules.

1612

4. Check minimum number of events

None

1612

5. Include endpoints

None

1612

6. Filter based on genotype QC (FinnGen only)

1462

Control definitions (FinnGen only)

Control exclude
Q17_CONGEN_MALFO_CIRCULATO_SYSTEM

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF6v3

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 13463 7684 5736
Only index persons 10427 6013 4414
Unadjusted period prevalence (%)
Whole population 0.19 0.22 0.16
Only index persons 0.20 0.22 0.17
Median age at first event (years)
Whole population 10.26 11.40 8.49
Only index persons 19.79 22.50 16.11

-FinnGen-

Key figures

All Female Male
Number of individuals 1462 899 563
Unadjusted period prevalence (%) 0.30 0.32 0.26
Median age at first event (years) 43.11 41.60 45.53

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1520
Matched controls
15097
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
6.9
311.1
773
1975
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
43.3
307.7
723
310
FFC22
NOMESCO Finland
Percutaneous transluminal closure of ostium secundum type ASD
+∞
307.7
387
*
Q21.11
ICD-10 Finland
Paten or persistent foramen ovale
+∞
307.7
335
*
Q21.19
ICD-10 Finland
Atrial septal defect NOS
+∞
307.7
450
*
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
23.8
307.7
321
168
XF620
NOMESCO Finland
Examination of circulation with color method
216.1
307.7
223
12
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
9.1
307.7
677
1230
Q21.10
ICD-10 Finland
Persistent ostium secundum
+∞
307.7
842
*
B01AA03
ATC
warfarin; systemic
7.8
287.8
509
918
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
41.3
239.8
147
39
FFC00
NOMESCO Finland
Suture of ostium secundum type ASD
+∞
218.6
205
*
201
Kela drug reimbursment
Chronic cardiac insufficiency
11.5
194.2
215
213
XF400
NOMESCO Finland
ECG with 12 standard connections
5.3
188.5
503
1291
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
6.6
163.8
301
544
XF404
NOMESCO Finland
Ambulatory ECG
6.5
162.6
304
559
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
7.7
156.9
243
366
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
13.4
156.8
154
126
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
6.5
152.1
281
509
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.9
144.0
953
4560
I48
ICD-10 Finland
Atrial fibrillation and flutter
4.6
135.5
407
1121
Q21.00
ICD-10 Finland
Multiple ventricular septal defect
+∞
126.6
120
*
7455A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ostium secundum type atrial septal defect
+∞
125.5
119
*
C01AA05
ATC
digoxin; systemic
7.3
125.1
197
300
FM2CE, ,
NOMESCO Finland
10.1
121.2
143
153
31
HP
Congenital heart failure surgery
+∞
121.2
115
*
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
+∞
121.2
115
*
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
15.2
118.7
107
75
Q21.08
ICD-10 Finland
Other specifed ventricular septal defect
+∞
116.9
111
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.9
112.4
426
1373
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.6
112.1
239
490
WX872
NOMESCO Finland
Intensive care
7.5
109.8
167
244
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
3.8
106.0
421
1395
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
57.7
98.7
56
10
Q21.18
ICD-10 Finland
Other spedified atrial septal defect
+∞
96.7
92
*
C03CA01
ATC
furosemide; systemic
3.3
95.5
484
1859
TFP20
NOMESCO Finland
Cardiodefibrillation
5.8
95.1
187
354
207
Kela drug reimbursment
Chronic arrhythmias
4.1
89.7
291
830
TPH07
NOMESCO Finland
Cathetrisation of artery
4.0
87.9
287
822
61
HP
Catheterization and pressure measurement of the left side of the heart
17.6
85.7
71
42
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
7.2
85.6
133
198
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
7.0
85.0
137
212
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
14.1
77.4
72
53
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
12.0
74.8
77
67
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
74.5
557
2601
5205
FHL
ASD blockage, secondary defect
+∞
73.3
70
*
5253
FHL
Cardiac lung machine
30.7
72.4
48
16
Q21.9
ICD-10 Finland
Congenital malformation of cardiac septum, unspecified
+∞
71.2
68
*
C03DA01
ATC
spironolactone; oral
3.8
71.1
252
758
XF402
NOMESCO Finland
ECG with work load test
4.1
70.8
220
603
74642
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium secundum
350.1
67.9
68
*
K78
ICPC
Atrial fibrillation/flutter
5.0
67.7
157
342
ZXE30
NOMESCO Finland
More than five and less than seven hours
5.0
66.5
151
323
I34.1
ICD-10 Finland
Mitral (valve) prolapse
8.2
66.3
91
117
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
6.3
65.9
116
196
ZXD10
NOMESCO Finland
Scheduled procedure
2.5
65.1
699
3837
Q21.1
ICD-10 Finland
Atrial septal defect
+∞
63.8
61
*
WX892
NOMESCO Finland
Monitored bed care
3.9
63.7
207
584
PA2AE
NOMESCO Finland
Ultrasound examination of brain artery
224.6
63.5
65
*
I50.9
ICD-10 Finland
Heart failure, unspecified
3.7
62.4
224
677
XFE00
NOMESCO Finland
Epicardial ultrasonography
10.5
61.6
69
68
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
5.0
60.9
138
294
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
11.0
60.8
66
62
C07AB07
ATC
bisoprolol; oral
2.4
59.6
694
3908
Q25.1
ICD-10 Finland
Coarctation of aorta
+∞
59.6
57
*
ZXE20
NOMESCO Finland
More than three and less than five hours
3.2
59.5
285
1030
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.6
59.3
455
2113
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
10.3
58.3
66
66
FFC50
NOMESCO Finland
Closure of ostium secundum type ASD using patch
+∞
57.5
55
*
XA800
NOMESCO Finland
Neuropsychological investigation
4.0
57.2
178
486
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
5.4
56.8
117
229
Q25.0
ICD-10 Finland
Patent ductus arteriosus
+∞
56.5
54
*
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
3.2
55.7
250
867
I50.0
ICD-10 Finland
Congestive heart failure
4.8
54.9
130
287
62
HP
Catheterization and pressure measurement of the right side of the heart
71.1
54.4
62
9
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
3.9
52.6
169
471
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
51.9
604
3352
Q23.11
ICD-10 Finland
Bicuspid aortic valve
267.7
51.3
52
*
TPX22
NOMESCO Finland
Intravenous arterial thrombolysis
19.4
50.7
40
21
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.3
50.7
210
692
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
6.1
49.5
89
153
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
20.3
49.2
38
19
FKB10
NOMESCO Finland
Annuloplasty of mitral valve for insufficiency using ring
15.9
48.4
42
27
B01AC04
ATC
clopidogrel; oral
3.0
48.3
245
908
XF622
NOMESCO Finland
Measurement of minute volume of heart
79.5
48.1
54
7
Q21.20
ICD-10 Finland
Atrial septal defect of primum type
+∞
48.1
46
*
R4150
NOMESCO Finland
Neuropsychological rehabilitation
11.6
48.0
50
44
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
3.1
47.5
221
779
APK
HP
ASD closure
+∞
47.0
45
*
Q22.1
ICD-10 Finland
Congenital pulmonary valve stenosis
+∞
47.0
45
*
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
4.1
46.5
135
349
AF1
HP
Surgery of congenital heart defect
+∞
46.0
44
*
R4110
NOMESCO Finland
Physiotherapy
2.2
44.6
520
2852
XF600
NOMESCO Finland
Bloodpressure measurement
3.4
44.1
177
570
Q21.12
ICD-10 Finland
Defective sinus venosus
+∞
43.9
42
*
Z2221
NOMESCO Finland
Medical doctor
2.2
43.1
502
2745
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
16.6
42.5
36
22
C07AA07
ATC
sotalol; systemic
5.9
41.2
76
134
APJ
HP
PFO closure
+∞
40.7
39
*
G04BE03
ATC
sildenafil; oral
10.4
39.4
44
43
C01BD01
ATC
amiodarone; systemic
6.4
38.9
66
107
Q21.21
ICD-10 Finland
Atrioventricular duct
+∞
38.6
37
*
XX3BT
NOMESCO Finland
Other labeling with X-ray guidance
8.5
38.4
50
60
XF640, ,
NOMESCO Finland
6.5
38.3
64
102
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.4
38.2
308
1431
I48.2
ICD-10 Finland
Chronic atrial fibrillation
4.6
36.7
89
200
7456A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Endocardial cushion defects[DEFECTUS SEPTI ATRIORUM NUD]
+∞
36.5
35
*
I49.5
ICD-10 Finland
Sick sinus syndrome
5.0
36.5
80
165
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
35.7
374
1937
FFC42
NOMESCO Finland
Percutaneous closure of patent foramen ovale
+∞
35.5
34
*
B01AF02
ATC
apixaban; oral
2.8
35.3
194
746
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
122.0
33.7
36
*
B01AB05
ATC
enoxaparin; parenteral
2.1
32.8
434
2449
Q20.3
ICD-10 Finland
Discordant ventriculoarterial connection
+∞
32.3
31
*
WX882
NOMESCO Finland
High dependency care
3.3
31.4
128
414
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
12.6
31.3
31
25
Q21.0
ICD-10 Finland
Ventricular septal defect
+∞
31.3
30
*
AN1
HP
Coronary angiography
3.0
31.2
148
524
AA1AD
NOMESCO Finland
CT of head and brain
2.0
30.3
402
2261
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
3.2
30.0
125
410
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
3.8
29.7
93
253
ZXD05
NOMESCO Finland
Urgent procedure
1.9
28.3
464
2799
Q20.1
ICD-10 Finland
Double outlet right ventricle
+∞
28.1
27
*
WX402
NOMESCO Finland
General anaesthesia
2.0
28.0
420
2456
AP2
HP
Catheterization of the right side of the heart
47.8
27.4
33
7
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
4.3
27.2
71
169
Q20.48
ICD-10 Finland
Single ventricle
+∞
27.1
26
*
I44.2
ICD-10 Finland
Atrioventricular block, complete
5.5
27.0
53
99
R4120
NOMESCO Finland
Occupational therapy
2.7
26.7
152
592
FXA10
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia at concurrent surgical procedure
273.9
26.7
27
*
I48.1
ICD-10 Finland
Persistent atrial fibrillation
4.3
26.3
70
169
TFP34
NOMESCO Finland
Electrophysiological investigation
4.1
26.1
73
183
K90
ICPC
Stroke/cerebrovascular accident
4.9
26.1
58
121
Q26.3
ICD-10 Finland
Partial anomalous pulmonary venous connection
+∞
26.0
25
*
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
9.5
26.0
31
33
K84
ICPC
Heart disease other
5.0
25.2
55
113
RS224, ,
NOMESCO Finland
7.7
24.9
35
46
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
5.3
24.9
51
99
FGC10
NOMESCO Finland
Annuloplasty of tricuspid valve using prosthetic ring
70.6
24.8
28
*
74639
ICD-8 Finland
Congenital anomalies of heart, Defectus septi ventriculorum
91.0
24.6
27
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
24.3
375
2200
FFC96
NOMESCO Finland
Other closure of isolated atrial septal defect
+∞
24.0
23
*
PD5BD
NOMESCO Finland
Extensive CT of aorta
7.5
23.6
34
46
I50.1
ICD-10 Finland
Left ventricular failure
3.9
23.3
70
185
ZXE00
NOMESCO Finland
One hour or less
1.7
23.3
612
4211
Q23.10
ICD-10 Finland
Congenital insufficiency of aortic valve
+∞
22.9
22
*
Q26.1
ICD-10 Finland
Persistent left superior vena cava
+∞
22.9
22
*
FHB50
NOMESCO Finland
Transatrial closure of VSD using patch
+∞
22.9
22
*
C01BC04
ATC
flecainide; systemic
3.9
22.4
66
172
TFP35
NOMESCO Finland
Electroanatomical mapping
5.7
22.0
41
73
C07AB02
ATC
metoprolol; systemic
2.1
21.9
242
1258
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
7.0
21.5
33
48
I35.0
ICD-10 Finland
Aortic (valve) stenosis
3.4
21.4
79
240
AP3
HP
Catheterization of the right and left side of the heart
43.7
21.4
26
6
Z98.8
ICD-10 Finland
Other specified postsurgical states
5.8
21.3
39
68
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
23.4
21.2
30
13
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
4.2
21.0
57
140
Q21.30
ICD-10 Finland
Tetralogy of Fallot
+∞
20.8
20
*
7454B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM SIMPLEX]
+∞
20.8
20
*
Z3231
NOMESCO Finland
Registered nurse
1.7
20.8
469
3068
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
4.2
20.7
56
137
C09AA05
ATC
ramipril; oral
1.9
20.5
291
1651
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.2
20.4
183
876
I48.4
ICD-10 Finland
Atypical atrial flutter
18.5
20.4
31
17
R06.0
ICD-10 Finland
Dyspnoea
1.8
20.3
387
2409
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
4.9
20.2
45
94
R04.0
ICD-10 Finland
Epistaxis
2.6
20.2
122
489
ZXE40
NOMESCO Finland
More than seven and less than nine hours
4.0
20.1
58
149
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
2.1
19.9
204
1030
I49.3
ICD-10 Finland
Ventricular premature depolarization
2.7
19.8
115
452
Q23.0
ICD-10 Finland
Congenital stenosis of aortic valve
+∞
19.8
19
*
Q21.29
ICD-10 Finland
Atrioventricular septal defect UNS
+∞
19.8
19
*
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
5.1
19.6
41
81
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
105.7
19.5
21
*
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.8
19.2
60
163
Z3226
NOMESCO Finland
Physiotherapist
1.8
19.2
323
1931
I42.0
ICD-10 Finland
Dilated cardiomyopathy
4.7
19.0
44
95
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
22.7
19.0
27
12
81
HP
Angiography of the heart and coronary arteries
3.3
18.9
73
228
74646
ICD-8 Finland
Congenital anomalies of heart, Defectus septi atriorum, ostium primum
+∞
18.7
18
*
I37.0
ICD-10 Finland
Pulmonary valve stenosis
+∞
18.7
18
*
FDF05
NOMESCO Finland
Percutaneous transluminal occlusion of aorto-pulmonary collaterals
+∞
18.7
18
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
18.6
217
1148
250, ,
Kela drug reimbursment
5.2
18.5
38
74
WX704
NOMESCO Finland
Intubation
2.4
18.5
137
604
FWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in surgery of heart and major thoracic vessels
19.5
18.1
27
14
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.3
18.0
69
215
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
3.7
17.9
58
162
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
17.8
377
2406
FBE10
NOMESCO Finland
Expansion or reconstruction of pulmonary artery using patch
+∞
17.7
17
*
Q25.40
ICD-10 Finland
Aortic hypoplasia
+∞
17.7
17
*
Q23.4
ICD-10 Finland
Hypoplastic left heart syndrome
+∞
17.7
17
*
I37.1
ICD-10 Finland
Pulmonary valve insufficiency
180.8
17.5
18
*
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
5.8
17.5
32
56
I47.1
ICD-10 Finland
Supraventricular tachycardia
2.8
16.8
86
317
FFC32
NOMESCO Finland
Percutaneous transluminal closure of sinus venosus type ASD
+∞
16.7
16
*
Q22.5
ICD-10 Finland
Ebstein anomaly
+∞
16.7
16
*
Q90.9
ICD-10 Finland
Down syndrome, unspecified
90.5
16.5
18
*
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
6.0
16.4
29
49
K83
ICPC
Heart valve disease NOS
12.2
16.3
29
24
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
16.3
255
1485
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.1
16.2
157
774
I47.2
ICD-10 Finland
Ventricular tachycardia
4.5
15.8
38
85
FAE00
NOMESCO Finland
Anastomosis to pulmonary artery from superior vena cava
+∞
15.6
15
*
Q24.4
ICD-10 Finland
Congenital subaortic stenosis
+∞
15.6
15
*
5255
FHL
Deep hypothermia (<20 °) with cardiopulmonary resuscitation
+∞
15.6
15
*
FPF20
NOMESCO Finland
Implantation of epicardial pacemaker with atrial and ventricular electrodes
+∞
15.6
15
*
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.2
15.6
147
716
FM1CD
NOMESCO Finland
Very extensive CT of heart
26.4
15.5
21
8
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
22.1
15.5
22
10
602
Kela drug reimbursment
Children's severe malnutrition
3.8
15.4
47
126
K80
ICPC
Cardiac arrhythmia NOS
2.3
15.2
125
576
ZXY02
NOMESCO Finland
Neuropsychologist
6.7
15.2
24
36
B01AE07
ATC
dabigatran etexilate; oral
3.5
14.9
51
148
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
6.5
14.8
24
37
I27.0
ICD-10 Finland
Primary pulmonary hypertension
31.8
14.8
19
6
74663
ICD-8 Finland
Congenital anomalies of heart, Stenosis valvulae pulmonalis
56.9
14.8
17
*
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
4.4
14.6
37
86
Q23.3
ICD-10 Finland
Congenital mitral insufficiency
+∞
14.6
14
*
FDA00
NOMESCO Finland
Aortoplasty and aorto-pulmonary shunt for HLHS
+∞
14.6
14
*
51
HP
Other heart surgery
+∞
14.6
14
*
I97.0
ICD-10 Finland
Postcardiotomy syndrome
36.2
14.4
18
5
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.5
14.4
93
385
TFP30
NOMESCO Finland
Cathetric examination for cardiac arrythmia
6.6
14.4
23
35
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.8
14.1
43
115
Q87.14
ICD-10 Finland
Noonan's syndrome
53.5
13.8
16
*
FAE10
NOMESCO Finland
Bidirectional anastomosis between superior vena cava and pulmonary artery
+∞
13.5
13
*
FBE32
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery
+∞
13.5
13
*
I44.1
ICD-10 Finland
Atrioventricular block, second degree
4.7
13.4
31
67
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
4.3
13.3
34
80
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
4.1
13.2
36
89
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
13.1
335
2226
FEB10
NOMESCO Finland
Decompression and drainage of pericardium
16.8
12.9
20
12
GE1BE
NOMESCO Finland
Mediastinal ultrasound examinaiton through oesophagus
28.4
12.9
17
6
I34.01
ICD-10 Finland
Mitral (valve) regurgitation NOS or of specified cause, except rheumatic
13.0
12.9
22
17
WX002
NOMESCO Finland
Sedation and analgesia
1.7
12.8
243
1492
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.8
12.7
206
1208
Q90.0
ICD-10 Finland
Trisomy 21, meiotic nondisjunction
70.0
12.6
14
*
I48.3
ICD-10 Finland
Typical atrial flutter
6.0
12.5
22
37
FBE35
NOMESCO Finland
Percutaneous transluminal angioplasty of pulmonary artery with insertion of stent
+∞
12.5
12
*
7460C
ICD-9 Finland
Other congenital anomalies of heart, Anomalies of pulmonary valve[VITIUM VALVULAE PULMONALIS CONGENITA CUM STENOSIS]
+∞
12.5
12
*
Q21.2
ICD-10 Finland
Atrioventricular septal defect
+∞
12.5
12
*
FJF20
NOMESCO Finland
Replacement of pulmonary valve using homograft
+∞
12.5
12
*
FXA20
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and circulatory arrest at concurrent surgical procedure
130.2
12.4
13
*
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
12.3
439
3148
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
11.7
12.3
22
19
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
12.2
642
4990
K99
ICPC
Cardiovascular disease other
4.0
12.1
34
86
Z31.5
ICD-10 Finland
Genetic counselling
2.1
12.0
118
583
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
4.5
12.0
29
65
AC4
HP
MVP
26.7
12.0
16
6
C10AA05
ATC
atorvastatin; oral
1.5
12.0
445
3214
I63
ICD-10 Finland
Cerebral infarction
10.1
11.9
23
23
FPD00
NOMESCO Finland
Maze procedure for atrial fibrillation
46.7
11.8
14
*
J01CA04
ATC
amoxicillin; systemic
1.7
11.8
1284
11542
R01.1
ICD-10 Finland
Cardiac murmur, unspecified
2.9
11.7
56
199
FPD96
NOMESCO Finland
Other operation for atrial fibrillation
65.0
11.6
13
*
AD1
HP
TVP
65.0
11.6
13
*
R50.9
ICD-10 Finland
Fever, unspecified
1.6
11.5
273
1775
K77
ICPC
Heart failure
4.1
11.5
31
76
I44.0
ICD-10 Finland
Atrioventricular block, first degree
5.3
11.4
23
44
Q25.41
ICD-10 Finland
Persistent right-sided aortic arch
+∞
11.4
11
*
AH3
HP
Treatment of arrhythmias, eg atrial fibrillation, in conjunction with other cardiac surgery
+∞
11.4
11
*
Q25.78
ICD-10 Finland
Other congenital malformations of pulmonary artery
+∞
11.4
11
*
I51.0
ICD-10 Finland
Cardiac septal defect, acquired
+∞
11.4
11
*
Q24.8
ICD-10 Finland
Other specified congenital malformations of heart
+∞
11.4
11
*
Q25.6
ICD-10 Finland
Stenosis of pulmonary artery
+∞
11.4
11
*
Q24.9
ICD-10 Finland
Congenital malformation of heart, unspecified
+∞
11.4
11
*
Q22.0
ICD-10 Finland
Pulmonary valve atresia
+∞
11.4
11
*
Q20.40
ICD-10 Finland
Double inlet left ventricle
+∞
11.4
11
*
74699
ICD-8 Finland
Congenital anomalies of heart, Unspecified anomalies of heart
120.1
11.4
12
*
Q24.3
ICD-10 Finland
Pulmonary infundibular stenosis
120.1
11.4
12
*
R62.0
ICD-10 Finland
Delayed milestone
2.8
11.4
57
208
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
4.7
11.3
26
56
Z2445
NOMESCO Finland
Psychologist
2.0
11.1
115
580
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.1
10.9
102
495
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
4.7
10.9
25
54
7AX01, ,
NOMESCO Finland
15.5
10.8
17
11
TFP45
NOMESCO Finland
Ablation treatment of non-typical atrial flutter
28.0
10.7
14
5
I34.0
ICD-10 Finland
Mitral (valve) insufficiency
4.3
10.7
27
63
H53.4
ICD-10 Finland
Visual field defects
3.6
10.5
34
95
342
Kela drug reimbursment
Dronedarone
8.5
10.5
22
26
APX
HP
Other cardiac catheter operation
+∞
10.4
10
*
FAE30
NOMESCO Finland
Total cavo-pulmonary connection using fenestrated patch
+∞
10.4
10
*
7454A
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Ventricular septal defect[DEFECTUS SEPTI VENTRICULORUM NUD]
+∞
10.4
10
*
Q24.6
ICD-10 Finland
Congenital heart block
+∞
10.4
10
*
Q90
ICD-10 Finland
Down syndrome
+∞
10.4
10
*
Q25.3
ICD-10 Finland
Stenosis of aorta
110.0
10.4
11
*
R1260
NOMESCO Finland
Evaluation of communicative skills
3.3
10.3
39
121
PD5CG
NOMESCO Finland
Extensive MRI examination of thoracal and abdominal aortta with high intensity magnet
32.5
10.3
13
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.3
10.3
80
361
3A064, ,
NOMESCO Finland
18.8
10.2
15
8
4273A
ICD-9 Finland
Cardiac dysrhythmias, Atrial fibrillation and flutter
7.5
10.1
23
31
FM1AD
NOMESCO Finland
CT of heart
13.1
10.1
17
13
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.1
10.1
42
138
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.9
9.9
119
633
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.1
9.8
91
441
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.0
9.8
103
523
TFC20
NOMESCO Finland
Catheterisation of both sides of heart
26.0
9.8
13
5
WW502
NOMESCO Finland
Autotransfusion
10.6
9.7
18
17
I49.8
ICD-10 Finland
Other specified cardiac arrhythmias
2.8
9.7
49
180
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
3.0
9.7
43
147
TFP44
NOMESCO Finland
Ablation treatment of typical atrial flutter
7.8
9.6
21
27
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
3.6
9.6
31
87
I21.19
ICD-10 Finland
Acute transmural myocardial infarction of inferior wall
5.3
9.6
19
36
FM1BD
NOMESCO Finland
Extensive CT of heart
11.4
9.5
17
15
L04AD02
ATC
tacrolimus; systemic
3.4
9.5
33
97
C01BD07
ATC
dronedarone; oral
9.1
9.5
19
21
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
9.1
9.5
19
21
FKC50
NOMESCO Finland
Repair of mitral valve for insufficiency using prosthetic chord
10.0
9.5
18
18
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
2.6
9.5
55
217
R42
ICD-10 Finland
Dizziness and giddiness
1.6
9.4
281
1922
7471A
ICD-9 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta[COARCTATIO AORTAE]
100.0
9.4
10
*
5207
FHL
VSD closure
+∞
9.4
9
*
FM2FN
NOMESCO Finland
Intra cardiac shunt isotope imaging
+∞
9.4
9
*
FBJ10
NOMESCO Finland
Anastomosis to pulmonary artery from subclavian artery with interposition graft
+∞
9.4
9
*
Q24.0
ICD-10 Finland
Dextrocardia
+∞
9.4
9
*
AE1
HP
Pulmonary artery thrombendarterectomy
+∞
9.4
9
*
Q20.5
ICD-10 Finland
Discordant atrioventricular connection
+∞
9.4
9
*
FDE10
NOMESCO Finland
Ligature of patent ductus arteriosus
+∞
9.4
9
*
ZSF00
NOMESCO Finland
Procedure related to previous procedure classified in chapter F
21.7
9.3
13
6
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
2.6
9.3
54
213
I49.1
ICD-10 Finland
Atrial premature depolarization
2.6
9.3
54
213
ZX199
NOMESCO Finland
Other rote
6.9
9.3
22
32
F83
ICD-10 Finland
Mixed specific developmental disorders
2.8
9.2
45
163
73
HP
Initial pacemaker installation
13.7
9.1
15
11
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.4
9.0
63
271
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
3.5
9.0
30
86
M41.1
ICD-10 Finland
Juvenile idiopathic scoliosis
4.1
8.9
24
59
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
2.5
8.9
56
230
UGC02
NOMESCO Finland
Rigid bronchoscopy
7.4
8.9
20
27
GD1AD
NOMESCO Finland
Thorax CT examination
2.1
8.8
81
392
PA7CD
NOMESCO Finland
CT angiography of neck and brain, extensive
4.9
8.8
19
39
Z94.1
ICD-10 Finland
Heart transplant status
8.6
8.8
18
21
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
4.0
8.5
24
61
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
8.5
407
3058
TKC20
NOMESCO Finland
Catheterisation of bladder
2.2
8.5
72
337
FPD10
NOMESCO Finland
Surgical ablation of atrial fibrillation
27.5
8.5
11
*
C02KX01
ATC
bosentan; oral
27.5
8.5
11
*
AB2
HP
AVR bio, stent
20.0
8.4
12
6
M01AE01
ATC
ibuprofen; systemic, rectal
0.7
8.4
1036
11337
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
2.5
8.3
49
195
Q21.80
ICD-10 Finland
Communication from left ventricle to right atrium
+∞
8.3
8
*
FFF96
NOMESCO Finland
Other operation for partially anomalous pulmonary veins
+∞
8.3
8
*
FLE96
NOMESCO Finland
Other repair of outlet obstruction of left ventricle
+∞
8.3
8
*
Q20.8
ICD-10 Finland
Other congenital malformations of cardiac chambers and connections
+∞
8.3
8
*
FGD00
NOMESCO Finland
Repair of tricuspid valve using suture
+∞
8.3
8
*
7456C
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Endocardial cushion defects[ASD CANALIS ATRIOVENTRICULARIS COMMUNIS]
+∞
8.3
8
*
Q25.48
ICD-10 Finland
Other congenital malformations of the aorta
+∞
8.3
8
*
I37.2
ICD-10 Finland
Pulmonary valve stenosis with insufficiency
+∞
8.3
8
*
1EA01, ,
NOMESCO Finland
+∞
8.3
8
*
GD1LA
NOMESCO Finland
GD
3.8
8.3
25
67
I34.2
ICD-10 Finland
Nonrheumatic mitral (valve) stenosis
14.5
8.2
13
9
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
3.5
8.2
27
77
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.9
8.1
38
134
AP1
HP
Catheterization of the left side of the heart
3.9
8.1
23
59
FFW96
NOMESCO Finland
Other operation on atria
33.3
8.1
10
*
D64.9
ICD-10 Finland
Anaemia, unspecified
1.8
8.1
113
633
Z2446
NOMESCO Finland
Social worker
1.7
8.1
153
936
289
Kela drug reimbursment
Combination product containing sacubitril and valsartan
4.7
8.0
18
38
TFP00
NOMESCO Finland
Temporary use of transvenous or epicardial pacemaker
4.7
8.0
18
38
C09AA02
ATC
enalapril; systemic
1.6
8.0
185
1189
127
Kela drug reimbursment
Transplant complication
2.8
8.0
38
135
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
6.8
8.0
19
28
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
8.0
267
1867
I34.9
ICD-10 Finland
Nonrheumatic mitral valve disorder, unspecified
10.0
8.0
15
15
H53.0
ICD-10 Finland
Amblyopia ex anopsia
3.1
7.9
32
104
EBA15
NOMESCO Finland
Extraction of multiple teeth
2.2
7.9
65
301
FKC60
NOMESCO Finland
Resection and reconstruction of leaflet of mitral valve for insufficiency
13.0
7.8
13
10
RS221, ,
NOMESCO Finland
2.8
7.8
37
132
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
2.4
7.8
51
214
3810A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Acute nonsuppurative otitis media
10.8
7.8
14
13
RK260, ,
NOMESCO Finland
10.8
7.8
14
13
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.2
7.7
64
298
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.6
7.7
164
1035
PA7BD
NOMESCO Finland
CT angiography of neck and brain
3.9
7.6
22
57
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
1.9
7.6
88
463
B01AF01
ATC
rivaroxaban; oral
1.7
7.6
132
788
FN1AD
NOMESCO Finland
CT of coronary arteries
3.2
7.6
29
91
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.5
7.6
220
1492
PA2VT
NOMESCO Finland
Intravascular evacuation of brain artery embolus
8.0
7.6
16
20
FPH00
NOMESCO Finland
Transvenous extraction of transvenous cardiac pacemaker or cardioverter-defibrillator
25.0
7.5
10
*
742, ,
NOMESCO Finland
25.0
7.5
10
*
AAL10
NOMESCO Finland
Intracranial endovascular thrombolysis
10.0
7.5
14
14
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
2.4
7.5
52
224
90492, ,
NOMESCO Finland
79.9
7.4
8
*
FFC40
NOMESCO Finland
Closure of Patent Foramen Ovale
79.9
7.4
8
*
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
6.0
7.3
19
32
WX870
NOMESCO Finland
Other postsurgical intensive care
8.3
7.3
15
18
FHB00
NOMESCO Finland
Transatrial suture of VSD
+∞
7.3
7
*
Q20.60
ICD-10 Finland
Left isomerism of atrial appendages
+∞
7.3
7
*
Q21.31
ICD-10 Finland
Tetralogy of Fallot and double outlet right ventricle
+∞
7.3
7
*
7451B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Transposition of great vessels[DOUBLE OUTLET RIGHT VENTRICLE]
+∞
7.3
7
*
74689
ICD-8 Finland
Congenital anomalies of heart, Aliae definitae
+∞
7.3
7
*
FK1AC
NOMESCO Finland
Right cardioangiography
+∞
7.3
7
*
FFF20
NOMESCO Finland
Anastomosis to left atrium from partially anomalous pulmonary veins
+∞
7.3
7
*
Q21
ICD-10 Finland
Congenital malformations of cardiac septa
+∞
7.3
7
*
FJE42
NOMESCO Finland
Percutaneous transluminal expansion of pulmonary valve
+∞
7.3
7
*
FJF10
NOMESCO Finland
Replacement of pulmonary valve using biological prosthesis
+∞
7.3
7
*
74719
ICD-8 Finland
Other congenital anomalies of circulatory system, Coarctation of aorta
+∞
7.3
7
*
1CX08, ,
NOMESCO Finland
10.8
7.3
13
12
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
2.5
7.3
44
178
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.5
7.2
215
1465
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.8
7.2
99
552
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
4.3
7.1
18
42
3AC01, ,
NOMESCO Finland
4.3
7.1
18
42
ZX120
NOMESCO Finland
Intravenous
1.7
7.1
122
725
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.4
7.1
48
204
7470A
ICD-9 Finland
Other congenital anomalies of circulatory system, Patent ductus arteriosus
30.0
7.1
9
*
C10AA01
ATC
simvastatin; oral
1.4
7.1
371
2820
ZX108
NOMESCO Finland
Inhalation
3.9
7.1
20
51
I31.9
ICD-10 Finland
Disease of pericardium, unspecified
6.6
7.1
17
26
I50
ICD-10 Finland
Heart failure
2.8
7.0
33
117
R47.0
ICD-10 Finland
Dysphasia and aphasia
5.6
7.0
19
34
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.5
7.0
41
163
FP1B5
NOMESCO Finland
Resting ECG, 12 leads
2.7
6.9
36
135
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
3.2
6.9
26
81
Z3229
NOMESCO Finland
Other healthcare associate professional
1.7
6.8
123
744
I36.0
ICD-10 Finland
Nonrheumatic tricuspid (valve) stenosis
40.0
6.7
8
*
AJ1
HP
Reconstruction of the aortic base, eg composite graft, incl. valve saving operation
40.0
6.7
8
*
Z95.9
ICD-10 Finland
Presence of cardiac and vascular implant and graft, unspecified
16.7
6.7
10
6
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
2.6
6.7
38
149
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
6.7
337
2542
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
6.7
293
2158
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.1
6.6
58
276
N02AX02
ATC
tramadol; systemic, rectal
1.4
6.6
477
3815
PH1AC
NOMESCO Finland
Flebography of over extremity with X-ray
3.7
6.6
20
54
K91
ICPC
Cerebrovascular disease
4.0
6.6
18
45
R20.2
ICD-10 Finland
Paraesthesia of skin
1.8
6.5
90
502
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.9
6.5
84
459
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
1.9
6.5
78
416
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
6.5
525
4267
P07.3
ICD-10 Finland
Other preterm infants
2.7
6.4
33
123
R07.2
ICD-10 Finland
Precordial pain
3.0
6.4
27
90
Q90.1
ICD-10 Finland
Trisomy 21, mosaicism (mitotic nondisjunction)
69.7
6.4
7
*
FXA13
NOMESCO Finland
Total cardiopulmonary bypass in deep hypothermia and exclusive cerebral perfusion
69.7
6.4
7
*
FGE10
NOMESCO Finland
Replacement of tricuspid valve using biological prosthesis
69.7
6.4
7
*
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
1.9
6.4
79
426
FKD00
NOMESCO Finland
Replacement of mitral valve using mechanical prosthesis
14.3
6.4
10
7
Z95.4
ICD-10 Finland
Presence of other heart-valve replacement
14.3
6.4
10
7
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
3.3
6.3
23
70
FP1C5
NOMESCO Finland
Resting ECG, 15 leads
3.3
6.3
23
70
A02BC02
ATC
pantoprazole; systemic
1.3
6.3
805
6969
C08DA01
ATC
verapamil; systemic
2.2
6.3
51
235
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
5.2
6.3
18
35
Z95.3
ICD-10 Finland
Presence of xenogenic heart valve
18.0
6.2
9
5
K73
ICPC
Congenital anomaly cardiovascular
+∞
6.2
6
*
FDE32
NOMESCO Finland
Percutaneous transluminal closure of patent ductus arteriosus
+∞
6.2
6
*
Q21.8
ICD-10 Finland
Other congenital malformations of cardiac septa
+∞
6.2
6
*
Q89.30
ICD-10 Finland
Situs inversus with dextrocardia
+∞
6.2
6
*
0034, ,
NOMESCO Finland
+∞
6.2
6
*
Q21.88
ICD-10 Finland
Other congenital malformations of cardiac septa
+∞
6.2
6
*
Q21.15
ICD-10 Finland
Common atrium
+∞
6.2
6
*
3AE00, ,
NOMESCO Finland
+∞
6.2
6
*
Q25.21
ICD-10 Finland
Interrupted aortic arch
+∞
6.2
6
*
ZF61V, ,
NOMESCO Finland
+∞
6.2
6
*
FMC96
NOMESCO Finland
Other operation on aortic valve for insufficiency
+∞
6.2
6
*
FHE30
NOMESCO Finland
Repair of tetralogy of Fallot with transannular patch
+∞
6.2
6
*
7456B
ICD-9 Finland
Bulbus cordis anomalies and anomalies of cardiac septal closure, Endocardial cushion defects[DEFECTUS SEPTI ATRIORUM, OSTII PRIMII]
+∞
6.2
6
*
Q21.81
ICD-10 Finland
Eisenmenger's syndrome
+∞
6.2
6
*
M41.9
ICD-10 Finland
Scoliosis, unspecified
3.3
6.2
23
71
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
6.1
544
4473
A12BA01
ATC
potassium chloride; oral
2.4
6.1
40
168
J96.1
ICD-10 Finland
Chronic respiratory failure
3.1
6.1
24
77
R00.2
ICD-10 Finland
Palpitations
1.7
6.1
111
672
D68.8
ICD-10 Finland
Other specified coagulation defects
3.5
6.1
20
57
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
2.8
6.1
29
104
R58
ICD-10 Finland
Haemorrhage, not elsewhere classified
3.2
6.1
23
72
P85
ICPC
Mental retardation
3.2
6.1
23
72
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
6.1
117
719
FQA00
NOMESCO Finland
Orthotopic transplantation of heart
12.5
6.1
10
8
J94.8
ICD-10 Finland
Other specified pleural conditions
3.8
6.0
18
48
42792
ICD-8 Finland
Symptomatic heart disease, Fibrillatio auricularis
8.6
6.0
12
14
FPJ04
NOMESCO Finland
Revision of pacemaker generator with atrial and ventricular electrodes
10.0
6.0
11
11
G46.4*I67.9
ICD-10 Finland
Cerebellar stroke syndrome
10.0
6.0
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
755
2886
4.18
164.77
6.4
3.3
1320.46
1048.63
ng/l
0.72
674
2404
592
1934
4.34
160.01
3.8
3.4
30.82
29.62
s
4.17
581
1889
1006
4886
4.09
151.07
30.3
11.1
1.48
1.18
inr
38.76
876
4058
314
707
5.30
133.59
3.7
3.5
225.11
178.34
ng/l
0.74
279
634
162
181
9.83
133.20
1.1
1.2
—
—
—
0
0
275
626
5.11
114.59
3.5
4.8
21.33
21.52
s
0.23
234
589
669
3077
3.07
97.03
2.7
2.7
—
—
—
0
0
148
229
7.00
91.99
1.3
1.3
4.31
4.59
u/ml
0.09
77
108
516
2121
3.14
90.01
4.4
3.7
1203.08
446.10
ng/l
2.01
414
1460
688
3319
2.93
89.93
6.5
5.6
80.66
91.27
%
20.31
681
3262
750
3989
2.71
78.40
2.8
2.7
—
—
—
0
0
929
5713
2.58
68.85
3.3
3.0
—
—
estimate
—
0
0
59
39
15.59
67.15
1.2
1.4
28.17
28.36
s
0.05
59
39
104
161
6.81
64.28
2.6
2.4
—
—
—
0
0
242
807
3.35
57.63
2.2
2.3
16.80
7.05
ug/l
4.47
217
711
311
1284
2.77
50.37
9.3
11.3
7.59
7.53
mmol/l
0.06
306
1243
429
2092
2.44
49.12
7.1
6.1
0.82
0.82
mmol/l
0.38
415
1997
178
555
3.48
46.75
4.8
5.6
3.06
3.28
g/l
1.31
172
537
601
3505
2.16
44.00
2.8
2.3
230.60
234.71
u/l
0.03
575
3361
39
28
14.17
42.27
3.6
8.9
4.97
5.14
kpa
0.23
39
28
1039
7583
2.14
40.54
9.5
6.0
6.20
6.47
mmol/l
6.40
1006
7150
275
1244
2.46
35.99
17.9
9.7
0.86
0.73
mmol/l
0.24
251
1036
273
1254
2.42
34.44
18.0
9.7
7.42
7.41
ph
1.23
124
668
183
726
2.71
31.19
22.5
12.1
0.64
0.66
%
0.30
183
721
187
751
2.68
31.11
22.0
11.8
1.23
1.28
%
0.35
187
744
319
1633
2.19
30.87
17.6
11.0
—
—
—
0
0
622
4076
1.87
29.67
4.9
3.4
56.15
57.21
ng/l
0.02
432
2594
824
5917
1.84
29.07
14.2
9.1
1.20
1.22
mmol/l
8.71
789
5531
47
74
6.48
28.46
1.1
1.1
1.07
1.05
ratio
0.53
42
65
307
1632
2.09
26.58
19.0
13.8
25.21
24.63
mmol/l
3.63
307
1626
32
7
46.31
26.46
2.6
5.1
98.78
97.29
g/l
—
32
7
461
2882
1.85
24.54
3.2
2.4
1.15
1.26
mg/l
0.35
344
2194
743
5384
1.73
23.50
6.2
6.0
36.45
36.55
g/l
0.18
702
5093
1430
12738
2.94
23.42
27.4
16.7
139.50
139.59
mmol/l
0.84
1424
12485
1430
12751
2.92
23.11
27.6
16.8
3.97
3.96
mmol/l
1.80
1423
12462
705
5082
1.70
22.35
7.5
8.5
—
—
—
0
0
839
6342
1.70
22.24
9.1
7.2
16.53
13.72
umol/l
2.39
798
6033
324
1864
1.92
22.02
3.6
2.9
21.23
22.77
%
1.45
306
1768
343
2034
1.87
21.15
3.5
2.8
2.43
2.40
g/l
0.46
321
1912
850
6507
1.67
20.95
12.3
9.2
1.21
1.22
mmol/l
5.80
774
5770
361
2187
1.84
20.75
3.6
2.8
12.78
13.68
umol/l
1.63
339
2067
58
153
3.87
19.37
3.1
3.3
0.78
0.83
nmol/l
0.23
46
128
471
3137
1.71
19.32
4.8
4.4
—
—
—
0
0
312
1864
1.83
18.53
6.8
7.9
7.37
7.37
ph
0.12
207
1167
64
189
3.47
18.13
8.4
6.7
11.60
11.39
mg/l
0.10
55
176
254
1433
1.91
18.01
7.3
8.5
24.17
23.76
mmol/l
1.61
254
1425
305
1827
1.82
17.90
6.8
7.8
1.56
1.39
mmol/l
0.44
272
1536
937
7525
1.62
17.65
7.5
8.1
1.85
2.09
e9/l
6.48
826
6569
920
7374
1.61
17.31
7.6
8.1
0.04
0.04
e9/l
1.06
793
6265
920
7376
1.61
17.27
7.5
8.1
0.58
0.57
e9/l
0.27
791
6267
224
1230
1.95
17.17
10.7
8.1
—
—
—
0
0
334
2079
1.76
17.15
9.7
8.5
1.20
1.16
mmol/l
1.32
324
1952
111
472
2.44
16.21
2.5
2.2
1.18
1.45
g/l
2.45
94
422
262
1544
1.83
16.08
10.2
7.7
7.42
7.41
ph
1.44
227
1252
559
4043
1.59
15.88
1.5
1.6
—
—
—
0
0
1419
12960
2.32
15.39
21.6
14.5
24.10
22.71
mg/l
1.01
1222
10322
932
7602
1.56
15.34
8.0
8.6
0.18
0.20
e9/l
3.04
819
6579
503
3592
1.58
14.86
5.6
3.2
—
0.70
—
0
10
854
6866
1.54
14.73
7.9
8.3
0.66
0.67
%
0.43
821
6517
140
693
2.11
14.23
4.9
6.6
1.19
1.23
%
0.26
140
688
873
7091
1.52
14.06
7.8
8.2
28.25
30.89
%
10.11
844
6796
852
6888
1.52
14.01
7.9
8.4
8.98
8.61
%
3.55
819
6540
36
85
4.28
13.98
2.1
1.4
71358.18
29301.81
e6/l
0.43
22
42
860
6972
1.52
13.91
7.6
8.1
56.46
54.13
%
6.96
835
6719
850
6877
1.52
13.86
7.9
8.3
2.84
2.99
%
1.11
817
6526
1446
13414
2.45
13.34
25.5
17.3
72.59
70.65
umol/l
1.21
1441
13256
486
3530
1.54
12.95
3.0
2.6
3.09
2.69
mg/l
2.34
437
3094
37
95
3.94
12.88
2.1
1.3
1430.68
1905.49
e6/l
0.38
25
61
961
8075
1.49
12.34
10.0
10.9
3.89
3.90
e9/l
0.08
839
6932
1428
13259
2.15
11.77
19.0
12.1
—
—
—
0
0
267
1733
1.64
11.32
2.7
2.0
—
—
—
0
0
582
4485
1.47
11.28
4.3
3.9
33.30
32.48
u/l
0.10
555
4274
800
6578
1.44
10.83
11.9
12.1
0.00
0.00
e9/l
0.02
632
5257
221
1382
1.69
10.78
3.5
3.3
0.20
0.21
g/l
0.99
216
1312
252
1633
1.64
10.71
5.0
4.7
8.46
7.26
umol/l
0.51
232
1397
134
727
1.91
10.52
11.0
15.1
1.24
1.21
mg/l
0.19
129
693
32
88
3.67
10.16
5.4
4.9
113.15
73.84
mg/l
0.85
27
76
1074
9382
1.47
10.16
9.5
7.8
89.95
89.17
u/l
0.13
1034
8918
31
84
3.72
10.05
2.1
1.4
—
—
—
0
0
86
405
2.18
9.95
3.9
2.4
702.27
407.84
ug/l
0.44
81
378
242
1589
1.61
9.70
3.5
4.7
1.91
1.66
%
2.27
225
1466
569
4462
1.43
9.65
6.8
7.5
—
—
—
0
0
153
892
1.78
9.55
2.1
3.1
64.99
66.61
g/l
1.43
142
835
34
103
3.33
9.36
46.8
46.4
7.50
6.74
ug/l
1.17
34
93
97
495
2.01
9.11
1.1
1.3
—
—
—
0
0
462
3524
1.43
8.99
4.7
4.2
7.40
7.40
ph
0.14
348
2484
18
20
9.03
8.99
1.1
1.1
—
—
—
0
0
812
6831
1.39
8.89
4.2
3.4
101.75
96.46
ug/l
0.34
770
6478
105
562
1.92
8.60
1.1
1.6
—
12.91
—
0
15
61
283
2.19
7.39
1.7
1.9
—
—
—
0
0
61
283
2.19
7.39
1.7
1.9
—
—
—
0
0
28
90
3.13
7.07
2.3
1.7
—
—
—
0
0
182
1203
1.57
7.02
3.2
3.8
76.62
68.81
e9/l
1.54
126
816
60
283
2.15
6.99
1.7
1.9
—
—
—
0
0
60
283
2.15
6.99
1.7
1.9
—
—
—
0
0
63
304
2.10
6.93
7.3
7.8
1.18
1.31
mmol/l
0.59
58
265
233
1636
1.49
6.80
1.8
1.7
1137.50
1191.41
nmol/l
0.39
178
1238
24
75
3.21
6.36
4.6
3.4
—
—
—
0
0
100
583
1.75
6.28
1.8
2.0
—
—
—
0
0
134
847
1.63
6.23
3.3
3.4
4.44
4.75
pmol/l
2.58
123
774
50
230
2.20
6.23
6.7
5.0
1.64
2.34
mmol/l
1.66
31
143
515
4209
1.33
6.05
3.4
3.4
2.36
2.37
mmol/l
0.72
469
3868
471
3803
1.33
6.01
3.0
2.8
62.30
81.13
u/l
0.43
443
3553
470
3862
1.30
5.15
4.1
3.7
0.46
0.36
e6/l
0.48
360
2793
524
4376
1.29
5.05
4.3
3.8
222.82
63.02
e6/l
0.43
415
3297
68
379
1.82
5.02
4.0
3.7
7.17
3.78
index
0.47
42
211
602
5137
1.27
4.83
5.1
4.5
47.98
81.24
e6/l
1.22
438
3479
103
652
1.61
4.81
1.8
2.4
—
—
—
0
0
95
592
1.63
4.73
1.5
1.9
4.02
7.54
iu/ml
1.61
21
117
211
1564
1.39
4.56
1.8
1.5
—
—
—
0
0
262
2012
1.35
4.55
1.4
1.4
693.62
482.64
titre
0.80
47
394
69
400
1.75
4.50
1.4
1.3
—
—
—
0
0
929
8384
1.26
4.49
5.1
4.5
201.00
2318.25
e6/l
1.96
19
107
311
2456
1.32
4.47
3.0
3.3
0.97
0.98
e6/l
0.02
169
1278
48
249
1.94
4.44
3.3
2.9
16.77
16.67
%
0.09
48
242
31
136
2.29
4.40
2.2
2.3
0.96
0.90
%
0.24
21
84
364
2950
1.30
4.32
3.7
3.0
4.99
6.30
e6/l
1.31
340
2664
31
138
2.26
4.26
2.4
2.5
31.65
32.51
pg
0.38
31
138
360
2927
1.29
4.15
3.8
3.2
346.04
329.18
umol/l
2.00
317
2630
445
3726
1.26
4.03
4.1
3.6
—
1.69
estimate
—
0
14
1234
11587
1.31
4.00
26.2
18.5
13.58
13.43
%
3.56
1226
11455
438
3670
1.26
3.93
3.1
3.0
—
—
—
0
0
216
1648
1.35
3.90
2.1
1.7
—
—
—
0
0
1266
11947
1.31
3.83
6.0
5.2
1.96
1.89
mu/l
1.34
1207
11236
26
114
2.29
3.73
5.3
4.8
1.19
0.72
index
1.57
26
114
82
526
1.58
3.68
1.4
1.7
1.12
1.18
g/l
1.35
76
504
147
1063
1.41
3.68
6.4
5.8
79.07
72.02
ng/l
0.72
131
981
172
1279
1.38
3.66
2.5
2.5
38.05
77.68
u/l
0.52
151
1063
48
268
1.80
3.60
5.9
4.4
—
—
—
0
0
19
75
2.54
3.42
1.8
1.5
31.64
37.17
%
0.22
11
52
382
3196
1.25
3.41
1.8
1.6
20.03
20.38
nmol/l
0.19
338
2754
275
2216
1.28
3.36
2.6
2.7
2.42
2.44
mmol/l
1.84
240
1978
50
290
1.74
3.33
4.6
4.6
91.55
90.87
%
0.29
50
279
1472
14305
1.70
3.30
32.5
22.0
29.97
29.91
pg
0.56
1467
14186
1472
14305
1.70
3.30
32.6
22.0
4.49
4.54
e12/l
3.73
1449
13911
1472
14306
1.70
3.29
35.4
22.7
39.85
40.84
%
1.75
1467
14180
30
148
2.03
3.26
1.2
1.1
—
—
—
0
0
1472
14309
1.69
3.24
32.6
22.1
6.76
6.77
e9/l
0.10
1450
13907
398
3364
1.24
3.22
3.5
3.7
—
0.05
—
0
22
1471
14298
1.68
3.22
32.6
22.1
246.64
259.61
e9/l
11.98
1452
13950
24
109
2.21
3.21
1.7
1.7
61.88
53.70
%
0.55
17
79
1471
14301
1.67
3.18
32.5
22.0
89.91
89.55
fl
1.89
1466
14183
641
5690
1.21
3.17
3.4
3.4
6.24
6.22
ph
0.13
322
3114
56
340
1.66
3.17
1.9
2.1
10.77
10.51
g/l
0.13
50
313
46
267
1.73
3.08
5.9
3.8
3.86
3.86
mmol/l
0.05
46
262
285
2337
1.26
3.01
3.3
3.4
3.12
2.61
e6/l
0.30
143
1165
77
513
1.52
2.98
1.5
1.7
0.22
0.23
g/l
0.58
72
493
9
21
4.28
2.97
2.1
1.6
38.58
22.19
g/l
—
9
15
65
421
1.56
2.86
2.5
2.0
0.68
1.96
ug/l
1.07
59
376
1164
10981
1.23
2.85
5.8
5.7
37.51
38.45
mmol/mol
4.05
1109
10426
28
143
1.96
2.80
2.3
3.3
—
—
—
0
0
62
400
1.56
2.79
1.2
1.2
—
—
—
0
0
212
1694
1.28
2.77
1.2
1.3
—
—
—
0
0
63
413
1.54
2.65
1.3
1.3
3.52
10.12
u/ml
0.90
14
49
51
318
1.61
2.65
2.6
2.5
—
—
—
0
0
1100
10347
1.20
2.64
5.0
4.3
14.91
14.59
pmol/l
4.19
1032
9605
63
414
1.53
2.63
1.3
1.3
2.10
4.69
u/ml
—
9
31
36
205
1.76
2.61
1.9
1.6
—
—
—
0
0
934
8672
1.18
2.55
4.3
3.8
49.99
43.51
u/l
1.19
904
8290
8
20
3.99
2.55
2.1
2.1
—
—
—
0
0
17
74
2.30
2.54
1.1
1.1
231.83
213.10
iu/ml
0.12
17
74
22
107
2.06
2.53
1.2
1.1
—
—
—
0
0
140
1071
1.33
2.53
5.0
5.5
0.07
0.14
%
0.59
41
285
36
592
0.59
2.51
1.0
1.2
2.64
3.17
u/ml
0.11
25
409
160
1251
1.30
2.48
1.3
1.4
143.79
289.83
u/ml
2.51
151
1176
99
721
1.39
2.45
1.2
1.2
—
—
—
0
0
22
109
2.02
2.42
36.4
39.2
148.29
140.16
ug/l
0.16
17
99
762
6986
1.17
2.35
4.0
3.8
20.99
5.95
estimate
0.50
130
1373
1187
11287
1.20
2.33
5.1
4.5
5.70
5.80
mmol/l
2.48
1113
10474
82
584
1.42
2.32
4.3
6.1
278.91
315.74
mg/l
0.23
56
355
307
2610
1.21
2.30
4.0
3.1
550.21
539.97
mosm/kgh2o
0.34
282
2298
562
5050
1.17
2.21
2.3
2.0
98.45
96.75
pmol/l
0.38
316
2671
51
334
1.53
2.20
5.6
3.9
1.19
1.36
mmol/l
1.40
51
326
135
1051
1.30
2.18
4.4
5.0
0.74
0.60
%
0.40
48
333
107
1381
0.75
2.15
1.7
1.7
—
—
—
0
0
45
674
0.65
2.13
1.1
1.2
5.26
3.03
u/ml
0.27
27
467
27
151
1.79
2.12
1.4
1.3
—
—
—
0
0
58
395
1.48
2.10
2.2
1.9
4.39
4.36
iu/l
0.01
20
161
139
1094
1.29
2.08
4.9
5.2
1.04
0.89
%
0.26
49
350
134
1050
1.29
2.08
5.0
5.2
0.22
0.10
%
0.71
43
304
5
10
4.98
2.06
2.4
1.8
—
—
—
0
0
512
4590
1.16
2.05
2.1
2.0
—
—
—
0
0
41
619
0.65
2.03
1.0
1.2
2.49
5.56
u/ml
1.36
27
442
40
606
0.65
2.02
1.0
1.2
1.35
0.98
u/ml
0.18
23
389
9
32
2.80
1.98
2.7
2.1
—
—
—
0
0
124
973
1.29
1.92
5.4
4.3
7.34
7.35
ph
0.23
93
703
12
52
2.30
1.85
1.6
1.2
—
—
—
0
0
12
52
2.30
1.85
1.6
1.2
—
—
—
0
0
12
52
2.30
1.85
1.6
1.2
—
—
—
0
0
48
324
1.49
1.85
4.4
4.1
8.51
9.44
umol/l
0.15
34
259
5
12
4.15
1.81
1.8
1.3
—
—
—
0
0
407
3616
1.16
1.81
4.1
3.9
0.00
0.01
estimate
1.28
118
1287
39
253
1.55
1.80
1.4
2.3
77.38
69.48
mmol/l
0.35
29
221
178
1470
1.23
1.80
1.2
1.3
—
—
—
0
0
747
6927
1.14
1.79
4.0
3.8
0.00
0.00
estimate
0.50
124
1360
104
1309
0.77
1.77
1.3
1.3
—
—
—
0
0
199
1666
1.21
1.76
2.4
3.2
3.99
4.99
e9/l
1.64
175
1483
24
394
0.60
1.74
1.0
1.1
0.02
0.68
u/ml
1.02
13
195
32
200
1.60
1.74
2.2
1.6
503.18
338.55
mu/l
0.90
25
163
26
416
0.61
1.70
1.1
1.1
4.28
9.91
u/ml
1.34
14
245
28
440
0.63
1.70
1.1
1.1
1.50
7.35
u/ml
5.81
17
280
755
7028
1.13
1.66
4.0
3.8
0.00
0.24
estimate
0.54
120
1299
20
111
1.80
1.65
1.4
2.1
—
—
—
0
0
425
3812
1.15
1.65
1.5
1.7
2.02
2.06
g/l
0.18
270
2230
10
42
2.37
1.61
3.4
3.4
39.56
30.50
mg/l
—
5
21
123
989
1.26
1.60
3.2
4.5
18.25
15.36
ug/l
0.07
100
800
24
143
1.68
1.58
1.4
3.5
—
—
—
0
0
58
421
1.38
1.56
1.5
1.4
282.79
309.40
ug/g
0.40
33
251
18
99
1.82
1.54
1.2
1.1
—
—
—
0
0
158
1312
1.22
1.54
3.5
3.5
10.11
9.93
g/l
0.17
149
1240
276
2410
1.17
1.53
1.4
1.3
17.32
27.04
iu/ml
3.22
77
676
57
417
1.37
1.47
2.8
3.5
126.38
3340.08
u/ml
0.75
49
357
45
316
1.43
1.47
1.7
1.8
30.77
21.62
ng/l
0.46
45
316
45
317
1.42
1.45
3.4
2.6
135.97
130.72
g/l
0.82
37
257
1144
10981
1.14
1.43
4.6
4.0
1.18
1.27
mmol/l
5.54
1080
10280
6
22
2.72
1.42
1.2
1.3
—
—
—
0
0
6
23
2.60
1.35
1.5
1.8
—
—
—
0
0
6
23
2.60
1.35
2.0
3.2
—
—
—
0
0
30
198
1.52
1.34
1.1
1.7
—
—
—
0
0
1208
11662
1.14
1.29
5.3
4.7
4.33
4.65
mmol/l
23.59
1156
11054
168
1933
0.85
1.26
1.7
1.8
—
—
—
0
0
9
44
2.04
1.25
1.1
1.5
66.87
79.16
nmol/24h
—
9
44
49
364
1.35
1.19
1.4
3.1
—
—
—
0
0
1215
11754
1.13
1.17
5.9
5.2
2.52
2.75
mmol/l
16.88
1154
11101
6
26
2.30
1.17
1.5
1.1
—
—
—
0
0
70
550
1.28
1.16
2.3
2.5
—
—
—
0
0
117
974
1.21
1.16
2.2
2.4
17.89
19.54
au/ml
0.09
11
104
1367
13340
1.18
1.13
14.5
11.6
25.72
26.21
u/l
0.51
1346
13022
15
244
0.61
1.12
1.1
1.6
10.29
16.50
u/ml
—
6
153
549
5105
1.11
1.12
1.8
1.9
1.27
1.36
mmol/l
2.02
469
4452
38
275
1.38
1.10
1.9
3.5
1.57
2.16
ratio
0.93
23
154
10
51
1.95
1.09
1.3
1.4
172.30
170.73
mmol/24h
—
10
51
33
235
1.40
1.06
8.6
4.7
8.01
7.76
pmol/l
0.08
33
235
18
113
1.59
1.03
1.2
1.2
0.43
0.56
ratio
4.08
13
63
30
211
1.42
1.03
2.6
2.5
24.32
19.32
iu/ml
—
5
15
19
121
1.57
1.03
1.6
1.8
—
—
—
0
0
34
245
1.39
1.02
4.1
3.8
4.12
4.11
e9/l
0.01
34
245
544
5079
1.10
1.01
3.7
3.6
4.83
0.03
estimate
0.49
104
1126
27
377
0.71
1.01
4.5
2.2
0.72
0.74
nmol/l
0.08
21
327
1196
11596
1.11
0.98
5.2
4.6
1.41
1.46
mmol/l
3.51
1140
10933
247
2214
1.13
0.98
1.4
1.3
10.08
9.27
u/ml
0.06
91
809
9
49
1.83
0.98
1.2
1.3
—
—
—
0
0
28
197
1.42
0.97
1.4
1.2
—
—
—
0
0
341
3117
1.11
0.96
3.8
3.7
1.02
1.51
kg/l
0.50
215
2061
108
912
1.19
0.95
1.2
1.2
—
—
—
0
0
34
249
1.36
0.95
1.2
1.1
—
—
—
0
0
73
597
1.23
0.90
2.3
2.1
0.00
1.21
estimate
0.51
18
210
17
252
0.67
0.89
1.0
1.5
1.62
3.55
u/ml
0.74
11
166
102
866
1.18
0.86
4.8
4.4
1.23
1.23
mmol/l
0.30
96
751
49
385
1.27
0.86
1.5
3.0
10.13
9.70
e6/l
0.02
39
284
13
79
1.64
0.86
1.0
1.1
—
—
—
0
0
40
306
1.31
0.86
2.1
3.7
48.60
61.82
mg/l
0.27
32
257
40
306
1.31
0.86
2.1
3.7
30.47
48.29
mg/l
0.85
32
258
122
1053
1.16
0.85
1.8
2.0
1.05
1.15
g/l
0.65
117
994
76
899
0.83
0.83
1.6
1.6
1204.59
984.39
mu/l
0.93
59
781
465
4899
0.92
0.83
2.9
2.9
—
—
—
0
0
13
80
1.62
0.82
1.0
1.0
—
—
—
0
0
8
47
1.69
0.80
1.6
1.2
—
—
—
0
0
49
390
1.26
0.79
1.5
3.0
165.55
796.61
e6/l
1.02
40
297
13
198
0.65
0.79
1.0
1.2
0.75
2.36
u/ml
—
8
113
42
525
0.79
0.78
1.1
1.1
0.64
0.67
ratio
—
7
56
5
96
0.52
0.78
1.0
1.1
—
1.32
nmol/l
—
0
19
8
48
1.66
0.78
1.0
1.1
—
—
—
0
0
56
454
1.23
0.78
2.3
1.9
—
—
—
0
0
27
198
1.36
0.77
1.0
1.2
58.83
24.01
u/l
0.72
22
174
45
557
0.80
0.77
1.1
1.1
1.47
1.52
g/l
0.64
45
557
8
131
0.60
0.73
1.9
2.3
—
—
—
0
0
47
574
0.81
0.73
1.2
1.2
0.82
0.90
g/l
1.63
47
574
365
3397
1.09
0.72
3.6
3.6
55.37
49.75
mg/l
0.16
231
2242
7
39
1.79
0.72
3.4
2.9
0.60
0.62
mmol/l
—
7
39
81
937
0.85
0.72
1.8
1.9
—
—
—
0
0
132
1165
1.14
0.71
2.1
2.1
0.00
0.02
estimate
0.78
22
264
154
1373
1.13
0.70
1.7
1.5
—
—
—
0
0
103
894
1.15
0.70
1.3
1.3
14.18
45.79
au/ml
—
9
56
28
211
1.32
0.69
1.5
1.4
22.25
20.03
u/l
0.14
20
179
26
194
1.34
0.69
2.9
4.5
—
—
—
0
0
7
42
1.66
0.68
1.1
1.2
—
—
—
0
0
125
1104
1.14
0.67
1.3
1.3
121.51
138.96
u/ml
0.20
46
409
105
1181
0.87
0.65
1.7
1.6
3.00
3.47
mmol/l
3.51
76
807
27
205
1.31
0.65
1.5
1.8
3.62
5.02
mmol/24h
1.35
22
184
13
86
1.51
0.64
2.2
2.2
—
—
—
0
0
141
1553
0.89
0.64
2.0
1.9
3.34
3.53
ratio
0.81
110
1181
51
605
0.83
0.62
1.1
1.1
—
—
—
0
0
41
497
0.81
0.62
1.5
1.5
78.92
61.35
ug/l
1.32
33
426
8
49
1.62
0.61
1.6
1.7
—
—
—
0
0
35
278
1.26
0.61
1.1
1.2
—
—
—
0
0
8
50
1.59
0.61
2.5
2.3
27.50
29.20
%
—
8
50
52
432
1.20
0.61
2.3
1.9
114.86
121.55
au/ml
0.18
22
157
18
130
1.38
0.59
1.2
1.2
100.06
114.80
pmol/l
0.66
18
130
0
22
0.00
0.59
0.0
1.4
—
72.50
—
0
22
56
654
0.84
0.58
2.6
2.5
—
—
—
0
0
77
875
0.87
0.57
1.8
2.0
—
—
—
0
0
16
114
1.40
0.57
1.3
1.8
—
—
—
0
0
328
3073
1.08
0.56
5.1
5.1
—
—
—
0
0
367
3454
1.07
0.56
4.2
4.2
11.21
8.29
mg/mmol
0.36
231
2217
20
149
1.34
0.56
1.3
1.3
—
—
—
0
0
443
4198
1.07
0.55
1.5
1.6
0.87
2.56
u/ml
5.94
110
1007
65
558
1.16
0.54
1.4
1.2
—
—
—
0
0
9
60
1.49
0.54
1.2
1.2
—
5.60
—
0
5
6
38
1.57
0.54
2.0
3.2
—
—
—
0
0
88
774
1.14
0.53
1.9
2.3
8869.44
5066.66
u/l
0.43
29
285
9
61
1.47
0.53
1.7
2.0
103.72
105.97
ng/l
—
9
61
35
285
1.22
0.51
1.8
1.6
16810.74
12419.50
e6/l
0.32
27
208
154
1403
1.10
0.51
1.3
1.4
—
—
—
0
0
26
206
1.26
0.49
1.4
1.4
—
—
—
0
0
84
935
0.89
0.48
1.8
2.0
—
—
—
0
0
7
46
1.51
0.48
2.3
2.3
—
—
—
0
0
31
374
0.82
0.48
1.6
1.5
—
—
—
0
0
21
163
1.28
0.46
1.5
1.2
—
—
—
0
0
30
244
1.23
0.46
3.1
3.7
1175.24
1444.89
e6/l
0.95
25
193
443
4224
1.06
0.46
3.7
3.8
7.45
7.89
mmol/l
1.15
381
3706
85
941
0.89
0.46
1.9
2.0
—
—
—
0
0
7
50
1.39
0.44
1.4
1.6
—
—
—
0
0
90
991
0.90
0.44
2.3
2.3
6.15
6.13
ph
0.08
52
649
32
381
0.83
0.44
1.6
1.5
—
—
—
0
0
85
937
0.90
0.43
1.8
2.0
—
—
—
0
0
20
156
1.28
0.43
1.3
1.3
—
—
—
0
0
73
646
1.13
0.43
1.1
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
5.6
—
8.25
—
0
15
15
113
1.32
0.41
1.5
1.2
—
—
—
0
0
24
291
0.82
0.40
1.5
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
50
435
1.15
0.39
1.2
1.1
6.12
14.11
au/ml
1.03
11
79
12
88
1.36
0.38
1.2
2.4
—
—
—
0
0
9
66
1.36
0.38
1.4
2.2
—
—
—
0
0
56
492
1.14
0.38
1.4
1.2
—
—
—
0
0
29
241
1.20
0.38
1.1
1.1
—
—
—
0
0
10
71
1.40
0.38
1.0
1.2
1060.00
558.33
titre
—
5
12
5
36
1.38
0.38
2.8
2.0
—
—
—
0
0
31
362
0.85
0.37
1.5
1.5
1.30
1.28
mm
0.06
22
262
199
1866
1.07
0.36
1.7
1.6
—
—
—
0
0
10
134
0.74
0.36
1.1
1.3
4.62
5.25
u/ml
—
10
127
338
3223
1.05
0.36
1.9
2.1
—
—
—
0
0
6
41
1.46
0.36
1.3
1.2
—
—
—
0
0
10
72
1.38
0.35
4.8
3.4
109.82
121.52
ug/l
—
10
72
165
1539
1.07
0.35
3.5
2.4
341.37
360.89
nmol/l
0.52
156
1461
19
232
0.81
0.35
1.0
1.0
19.37
19.42
mmol/l
0.02
19
224
9
123
0.73
0.35
1.0
1.1
337.33
287.83
mg/l
—
9
113
11
81
1.35
0.35
1.0
1.2
—
—
—
0
0
6
43
1.39
0.35
1.0
1.0
—
—
—
0
0
69
754
0.90
0.32
1.8
2.0
—
—
—
0
0
39
440
0.88
0.31
2.2
2.4
—
—
—
0
0
19
228
0.83
0.31
1.0
1.0
—
—
—
0
0
19
228
0.83
0.31
1.0
1.0
-2.11
-2.24
mmol/l
—
8
49
25
292
0.85
0.31
1.2
1.1
2.37
4.48
eliau/ml
0.72
11
112
21
174
1.20
0.30
6.2
3.8
1.73
1.68
umol/l
0.14
21
168
7
56
1.24
0.29
1.9
2.4
15.44
17.95
umol/l
—
7
56
107
993
1.08
0.28
1.8
1.5
—
—
—
0
0
8
63
1.26
0.27
1.3
1.2
—
—
—
0
0
10
76
1.31
0.27
1.2
1.1
1446.80
1436.70
miu/ml
—
10
76
32
279
1.14
0.26
1.4
1.4
82.36
138.86
pmol/l
0.70
32
272
22
186
1.18
0.26
1.2
1.3
—
—
—
0
0
19
223
0.84
0.26
1.1
1.1
8.46
15.56
u/ml
—
8
57
15
122
1.22
0.25
1.6
2.5
1.05
1.31
g/24h
—
6
80
12
95
1.26
0.25
2.8
3.5
1035.75
898.37
u/ml
0.15
12
95
49
443
1.10
0.24
1.1
1.1
2.91
7.18
eliau/ml
—
7
75
158
1644
0.95
0.23
1.3
1.2
—
—
—
0
0
27
235
1.14
0.23
1.1
1.2
—
—
—
0
0
18
210
0.85
0.23
1.6
1.8
—
—
—
0
0
38
339
1.12
0.23
15.3
9.1
—
—
—
0
0
5
37
1.34
0.23
1.4
1.3
—
—
—
0
0
5
38
1.31
0.23
1.0
1.7
6.52
239398.25
nmol/l
—
5
33
107
1003
1.06
0.23
5.0
3.9
—
—
—
0
0
44
398
1.10
0.22
4.2
3.2
55.50
55.68
%
0.03
44
398
233
2235
1.04
0.21
1.5
1.7
453.51
33264144.44
pmol/l
2.40
195
1915
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
2.0
—
3.18
—
0
5
39
351
1.11
0.21
1.2
1.2
—
—
—
0
0
8
102
0.78
0.21
2.5
2.1
119.38
123.83
ng/l
—
8
88
156
1617
0.95
0.21
2.9
2.9
0.79
0.72
ug/l
0.20
97
923
101
949
1.06
0.21
1.8
1.8
22.57
20.89
iu/l
0.19
78
717
46
419
1.09
0.20
1.3
1.2
—
—
—
0
0
22
191
1.15
0.20
2.5
4.3
9772.40
1644.07
u/ml
0.39
22
180
12
98
1.22
0.20
3.1
2.6
42.57
42.85
%
—
7
50
27
239
1.12
0.19
4.0
4.3
—
—
—
0
0
6
52
1.15
0.19
1.5
1.7
0.00
0.06
estimate
—
6
52
6
52
1.15
0.19
4.8
2.5
512.67
513.15
min
—
6
39
11
90
1.22
0.18
1.1
1.1
—
—
—
0
0
22
193
1.13
0.18
1.4
1.9
—
1930.00
—
0
8
273
2642
1.03
0.17
1.7
1.7
—
—
—
0
0
24
213
1.12
0.17
3.4
3.8
312.89
202.43
e6/l
0.67
19
163
24
213
1.12
0.17
3.3
3.8
367.58
536.72
e6/l
1.62
19
158
8
71
1.12
0.16
2.6
3.4
7.73
10.73
mg/l
—
8
61
45
417
1.07
0.15
1.3
1.2
—
—
—
0
0
10
83
1.20
0.14
1.2
1.4
78.10
74.98
umol/l
—
10
83
273
2652
1.03
0.14
4.5
4.7
1.61
2.05
ug/l
1.56
241
2430
621
6094
1.02
0.14
3.3
2.9
76.17
74.29
nmol/l
0.90
569
5634
38
351
1.08
0.13
5.7
4.4
25.44
22.84
nmol/l
0.44
38
343
29
311
0.92
0.12
1.1
1.1
—
—
—
0
0
13
113
1.14
0.12
1.0
1.0
—
—
—
0
0
20
180
1.10
0.12
1.4
2.0
—
—
—
0
0
16
142
1.12
0.11
1.1
1.1
—
—
—
0
0
24
219
1.09
0.11
1.7
3.1
—
—
—
0
0
17
187
0.90
0.11
1.3
1.5
—
—
—
0
0
85
876
0.96
0.11
1.8
1.6
—
—
—
0
0
10
114
0.87
0.10
1.1
1.0
—
—
—
0
0
75
717
1.04
0.10
1.9
2.0
8.60
7.51
u/l
0.29
46
475
12
105
1.14
0.10
3.3
2.7
—
—
—
0
0
26
240
1.08
0.10
1.8
4.0
—
—
—
0
0
5
47
1.06
0.09
1.0
1.3
—
—
—
0
0
55
570
0.96
0.09
2.9
3.2
1.02
1.02
ratio
0.25
48
524
10
113
0.88
0.09
1.1
1.1
—
—
—
0
0
14
154
0.90
0.09
1.0
1.3
3.51
23.68
u/ml
—
8
120
17
154
1.10
0.09
7.3
4.1
23.35
26.56
umol/l
1.48
17
149
55
524
1.04
0.09
1.9
1.7
277.37
211.36
u/ml
0.83
41
267
26
242
1.07
0.08
1.0
1.1
12.78
7.10
iu/ml
—
6
43
38
396
0.95
0.08
1.1
1.2
—
—
—
0
0
8
73
1.09
0.07
1.3
1.4
—
—
—
0
0
13
142
0.91
0.07
1.1
1.3
—
—
—
0
0
7
84
0.83
0.07
1.0
1.1
27.31
37.20
iu/ml
—
7
84
9
84
1.06
0.07
1.4
1.2
173.80
166.24
pmol/l
—
9
84
224
2256
0.98
0.07
2.1
3.0
114.24
106.75
ug/g
0.14
169
1845
48
495
0.96
0.07
1.7
1.7
34.73
9.44
u/ml
—
6
122
50
515
0.96
0.07
1.7
1.9
—
—
—
0
0
125
1218
1.02
0.06
1.5
1.5
—
—
—
0
0
14
151
0.92
0.06
1.3
1.4
—
—
nmol/l
—
0
0
119
1160
1.02
0.06
2.4
2.4
10.71
12.09
nmol/l
1.10
109
1057
68
658
1.03
0.05
1.6
1.7
0.22
0.31
mg/l
0.58
25
300
10
109
0.91
0.04
1.0
1.1
—
—
—
0
0
20
209
0.95
0.04
1.7
1.6
—
—
—
0
0
24
249
0.96
0.04
2.1
2.0
—
9.33
—
0
6
69
699
0.98
0.03
1.8
1.7
—
—
—
0
0
42
428
0.97
0.03
1.6
1.5
66.67
90.00
titre
—
6
50
376
3717
1.01
0.02
3.5
3.1
0.96
0.03
estimate
0.78
106
1112
14
147
0.95
0.02
1.4
1.2
—
—
—
0
0
17
176
0.96
0.01
2.8
4.2
0.39
0.38
e9/l
0.02
12
113
22
225
0.97
0.01
1.1
1.1
—
—
—
0
0
28
284
0.98
0.00
1.3
1.7
0.61
0.77
g/l
0.52
22
240
18
173
1.03
0.00
1.3
1.4
0.68
0.58
nmol/l
0.59
18
165
14
138
1.01
0.00
1.0
1.1
—
—
—
0
0
22
220
0.99
0.00
3.0
2.3
126.08
104.33
ug/min
0.09
12
141
31
307
1.00
0.00
1.8
1.5
0.54
0.36
nmol/l
0.25
25
243
13
124
1.04
0.00
2.3
2.3
15.14
30.08
mg/l
—
7
84
57
569
0.99
0.00
1.4
1.3
253.55
234.20
miu/ml
0.14
27
266
10
94
1.06
0.00
3.9
2.7
73.70
56.23
umol/l
—
10
86
0
8
0.00
0.00
0.0
2.5
—
178.50
—
0
8
0
9
0.00
-0.00
0.0
1.0
—
11.54
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.04
—
0
5
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
79
1.01
-0.00
1.0
1.2
20.38
8.62
mm/h
—
8
79
0
9
0.00
-0.00
0.0
1.9
—
342.78
—
0
9
0
5
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
299.40
—
0
5
9
89
1.00
-0.00
9.6
12.2
0.77
0.60
mmol/l
—
9
83
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
516.50
—
0
6
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.6
—
217.00
—
0
5
6
69
0.86
-0.00
1.3
2.1
—
—
—
0
0
6
62
0.96
-0.00
1.0
1.3
126.83
144.36
nmol/l
—
6
62
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
6
65
0.92
-0.00
1.3
1.4
—
86.00
%
—
0
10

Mortality – FinRegistry

Association

Association between endpoint Q17_ASD and mortality.

Females

Parameter HR [95% CI] p-value
Q17_ASD 1.807 [1.57, 2.09] < 0.001
Birth year 0.999 [0.99, 1.01] 0.845

During the follow-up period (1.1.1998 — 31.12.2019), 451 out of 5990 females with Q17_ASD died.

Males

Parameter HR [95% CI] p-value
Q17_ASD 1.752 [1.5, 2.04] < 0.001
Birth year 0.987 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 363 out of 4494 males with Q17_ASD died.

Mortality risk

Mortality risk for people of age

years, who have Q17_ASD.

N-year risk Females Males
1 0.2% 0.337%
5 1.099% 2.003%
10 2.988% 5.23%
15 5.839% 9.857%
20 10.621% 15.809%

Relationships between endpoints

Index endpoint: Q17_ASD – Atrial septal defect

GWS hits: 4

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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