Discitis, unspecified

M13_DISCITIS

discitis: Inflammation of an intervertebral disc or disk space which may lead to disk erosion. Until recently, discitis has been defined as a nonbacterial inflammation and has been attributed to aseptic processes (e.g., chemical reaction to an injected substance). However, recent studies provide evidence that infection may be the initial cause, but perhaps not the promoter, of most cases of discitis. Discitis has been diagnosed in patients following discography, myelography, lumbar puncture, paravertebral injection, and obstetrical epidural anesthesia. Discitis following chemonucleolysis (especially with chymopapain) is attributed to chemical reaction by some and to introduction of microorganisms by others.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M46.4
  • Cause of death: ICD-10 M46.4

2 out of 7 registries used, show all original rules.

727

4. Check minimum number of events

None

727

5. Include endpoints

None

727

6. Filter based on genotype QC (FinnGen only)

654

Control definitions (FinnGen only)

Control exclude
M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M46
Name in latin
Discitis non specificata

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3832 1518 2294
Only index persons 3640 1453 2187
Unadjusted period prevalence (%)
Whole population 0.06 0.04 0.06
Only index persons 0.07 0.05 0.08
Median age at first event (years)
Whole population 64.99 67.41 63.41
Only index persons 64.70 66.94 63.21

-FinnGen-

Key figures

All Female Male
Number of individuals 654 258 396
Unadjusted period prevalence (%) 0.15 0.09 0.18
Median age at first event (years) 67.29 65.86 68.22

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
670
Matched controls
6700
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
191.8
307.7
182
13
M46.4
ICD-10 Finland
Discitis, unspecified
4503599627370496.0
307.7
669
*
M48.0
ICD-10 Finland
Spinal stenosis
69.2
300.5
167
32
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
26.2
290.3
223
125
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
32.8
221.2
149
58
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
42.3
215.2
133
39
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
29.7
213.4
149
64
M54.5
ICD-10 Finland
Low back pain
8.1
166.1
383
949
M46.3
ICD-10 Finland
Infection of intervertebral disc (pyogenic)
+∞
165.7
152
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
7.9
141.6
259
495
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
61.9
119.8
67
12
M54.9
ICD-10 Finland
Dorsalgia, unspecified
10.5
118.7
147
175
N03AX16
ATC
[U] pregabalin
6.7
116.3
249
547
M54.4
ICD-10 Finland
Lumbago with sciatica
8.4
116.0
179
279
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
7.5
114.4
201
361
NA3DG
NOMESCO Finland
Lumbar spine very extensive MRI examination with high intensity magnet
256.9
108.1
108
5
J01FF01
ATC
clindamycin; systemic
5.2
99.2
347
1148
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
24.3
98.9
72
33
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
20.3
96.4
76
42
N03AX12
ATC
[U] gabapentin; oral
6.9
93.1
172
321
N02AX02
ATC
tramadol; systemic, rectal
5.0
92.4
424
1713
N02AA05
ATC
oxycodone; systemic
5.2
92.3
274
786
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
22.8
91.1
68
33
L03
ICPC
Low back symptom/complaint
4.9
85.8
274
827
A41.9
ICD-10 Finland
Sepsis, unspecified
10.1
85.0
104
120
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
6.7
79.2
144
262
J04AB02
ATC
rifampicin; systemic
24.4
77.4
56
25
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.8
76.6
136
241
R50.9
ICD-10 Finland
Fever, unspecified
4.8
72.6
213
591
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
14.2
70.0
66
51
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
134.2
68.4
72
6
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.1
65.0
263
919
A41.8
ICD-10 Finland
Other specified sepsis
13.8
64.8
62
49
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
179.6
63.2
65
*
J01MA12
ATC
levofloxacin; systemic
4.0
61.3
238
803
A40.8
ICD-10 Finland
Other streptococcal sepsis
17.0
61.2
52
33
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.0
60.8
476
2545
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.0
60.7
239
814
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.7
60.4
170
451
ZXD05
NOMESCO Finland
Urgent procedure
3.7
60.1
316
1304
C03CA01
ATC
furosemide; systemic
3.6
59.4
355
1588
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
28.3
58.6
40
15
N02BF01
ATC
gabapentin; oral
6.2
56.7
108
203
J01CF05
ATC
flucloxacillin; systemic
5.9
55.8
112
221
A46
ICD-10 Finland
Erysipelas
4.1
55.6
199
629
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
21.3
55.1
42
21
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
8.8
54.7
72
90
N02AJ06
ATC
codeine and paracetamol; systemic
3.4
53.6
356
1673
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.2
51.9
174
522
JN3AD
NOMESCO Finland
Abdominal CT examination
4.2
50.4
165
486
G06.1
ICD-10 Finland
Intraspinal abscess and granuloma
+∞
48.5
46
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.0
48.2
168
516
SPAT1255
SPAT
Intravenous administration of medicine
5.1
45.9
108
244
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
3.1
44.2
352
1783
TPH04
NOMESCO Finland
Cathetrisation of vein
3.3
43.9
231
922
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
+∞
43.2
41
*
L28
ICPC
Limited function/disability (L)
3.4
42.7
206
778
N06AX21
ATC
duloxetine; oral
4.8
41.4
105
252
N17.9
ICD-10 Finland
Acute renal failure, unspecified
6.0
41.0
78
145
M54.8
ICD-10 Finland
Other dorsalgia
10.2
40.8
47
49
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
6.7
40.7
68
111
JN4AD
NOMESCO Finland
Body CT examination
3.7
40.6
160
530
N02BF02
ATC
pregabalin; oral
6.5
40.1
69
116
A02BC02
ATC
pantoprazole; systemic
3.5
39.8
533
3525
S97
ICPC
Chronic ulcer skin
4.7
39.6
101
243
TPH40
NOMESCO Finland
Insertion of a long peripheral venous catheter
16.2
39.4
34
22
M03BC01
ATC
orphenadrine (citrate); systemic
3.5
38.9
169
595
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
67.1
38.6
44
7
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
206.7
38.2
39
*
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
9.6
38.1
46
51
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.9
37.7
262
1208
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.9
37.7
131
397
B01AB05
ATC
enoxaparin; parenteral
2.8
37.2
292
1434
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
+∞
36.8
35
*
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
376.7
36.3
36
*
H02AB06
ATC
prednisolone; systemic
2.8
36.3
386
2207
M46.2
ICD-10 Finland
Osteomyelitis of vertebra
+∞
35.7
34
*
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
10.8
35.4
39
38
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.1
35.4
111
312
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
12.7
35.3
35
29
L86
ICPC
Back syndrome with radiating pain
6.2
34.9
63
111
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.8
34.6
265
1275
X59
ICD-10 Finland
Exposure to unspecified factor
3.2
34.4
174
667
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
53.0
33.9
40
8
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
32.9
230
1051
I50.9
ICD-10 Finland
Heart failure, unspecified
3.1
32.9
175
689
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.3
32.8
150
540
J01DB01
ATC
cefalexin; oral
4.1
32.1
598
4473
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.1
31.8
95
257
S18
ICPC
Laceration/cut
2.6
31.7
387
2313
AA1AD
NOMESCO Finland
CT of head and brain
2.6
31.7
276
1404
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.2
31.5
154
576
N02BE01
ATC
paracetamol; systemic, rectal
8.0
31.5
645
5121
A28
ICPC
Limited function/disability NOS
2.9
31.3
199
862
J01MA02
ATC
ciprofloxacin; systemic
2.6
31.2
332
1855
A01
ICPC
Pain general/multiple sites
4.1
31.2
96
265
M13.9
ICD-10 Finland
Arthritis, unspecified
4.4
30.7
83
208
M04AA01
ATC
allopurinol; systemic
3.0
30.4
162
636
M54
ICD-10 Finland
Dorsalgia
3.9
30.4
99
285
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
5.2
30.1
65
135
M54.3
ICD-10 Finland
Sciatica
7.9
30.0
42
56
UJF32
NOMESCO Finland
Coloscopy
2.7
29.9
232
1109
SPAT1254
SPAT
Administration of medicine
3.1
29.6
148
559
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.4
28.9
117
389
TQW11
NOMESCO Finland
Vacuum treatment of wound
8.2
28.8
39
50
M47.82
ICD-10 Finland
Other spondylosis, cervical region
27.5
28.7
39
15
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.1
28.6
86
233
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.0
28.6
153
600
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.7
28.1
197
891
M54.2
ICD-10 Finland
Cervicalgia
4.9
27.9
64
140
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.5
27.4
279
1506
NF1AA
NOMESCO Finland
Hip X-ray examination
3.6
27.3
99
306
M79.6
ICD-10 Finland
Pain in limb
2.4
27.1
309
1752
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.6
27.0
101
318
M47.9
ICD-10 Finland
Spondylosis, unspecified
43.3
27.0
33
8
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
9.6
26.7
32
35
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.1
26.7
78
207
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.4
26.6
310
1771
R4110
NOMESCO Finland
Physiotherapy
2.5
26.2
236
1199
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
+∞
26.2
25
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.7
26.2
91
273
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.5
26.0
67
161
M03BX02
ATC
tizanidine; oral
2.4
26.0
400
2569
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
270.5
25.9
26
*
N06AA09
ATC
amitriptyline; systemic
4.0
25.8
78
212
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
23.7
25.5
36
16
TKC20
NOMESCO Finland
Catheterisation of bladder
3.8
25.4
85
248
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
6.0
25.4
46
81
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.5
25.2
231
1180
A06AD11
ATC
lactulose; oral
2.9
25.1
145
590
R60.0
ICD-10 Finland
Localized oedema
3.1
25.1
122
451
A07EC01
ATC
sulfasalazine; oral, rectal
4.1
25.0
73
193
NA1AD
NOMESCO Finland
Cervical spine CT examination
5.2
25.0
53
108
TPH07
NOMESCO Finland
Cathetrisation of artery
3.0
25.0
125
469
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
7.3
24.8
37
53
ZXD35
NOMESCO Finland
Usual procedure
6.1
24.3
43
74
L70
ICPC
Infection of musculoskeletal system
58.3
24.2
28
5
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
4.2
24.1
67
171
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
32.4
23.9
31
10
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
23.9
285
1626
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.2
23.1
65
167
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.6
22.9
81
245
WX110
NOMESCO Finland
Infiltration anesthesia
2.4
22.7
491
3558
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.0
22.5
112
418
R06.0
ICD-10 Finland
Dyspnoea
2.3
22.5
227
1200
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.7
22.3
77
229
C07AB07
ATC
bisoprolol; oral
2.2
22.1
397
2650
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.7
22.1
146
634
TK800
NOMESCO Finland
Hemodialysis
6.1
22.0
39
67
M46.5
ICD-10 Finland
Other infective spondylopathies
+∞
22.0
21
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
5.2
21.9
46
93
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.6
21.9
78
237
SPAT1229
SPAT
Assessment of need for aid
3.6
21.9
78
237
I10
ICD-10 Finland
Essential (primary) hypertension
2.4
21.9
490
3573
M54.6
ICD-10 Finland
Pain in thoracic spine
4.9
21.8
50
109
Z3226
NOMESCO Finland
Physiotherapist
2.6
21.8
146
638
JN4BD
NOMESCO Finland
Extensive body CT
2.9
21.6
120
475
B01AA03
ATC
warfarin; systemic
2.4
21.4
190
946
P19
ICPC
Drug abuse
35.1
21.3
27
8
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.8
21.1
126
518
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
6.7
21.1
34
53
NA1DG
NOMESCO Finland
Cervical spine very extensive MRI examination with high intensity magnet
+∞
20.9
20
*
NAS20
NOMESCO Finland
Incision and debridement of infection of vertebra, unspecified
+∞
20.9
20
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
4.1
20.7
59
153
Z3231
NOMESCO Finland
Registered nurse
2.3
20.6
217
1161
M43.1
ICD-10 Finland
Spondylolisthesis
19.1
20.6
31
17
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
26.5
20.6
28
11
M10.9
ICD-10 Finland
Gout, unspecified
3.2
20.5
91
317
L04AA13
ATC
[U] leflunomide
7.4
20.5
30
42
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
4.4
20.5
54
132
L17
ICPC
Foot/toe symptom/complaint
2.3
20.5
224
1217
M00.9
ICD-10 Finland
Pyogenic arthritis, unspecified
8.7
20.3
26
31
J01XX08
ATC
linezolid; systemic
28.1
20.2
27
10
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
8.2
20.1
27
34
ABC26
NOMESCO Finland
Open discectomy of lumbar spine
+∞
19.9
19
*
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
+∞
19.9
19
*
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.5
19.7
71
217
J01CF02
ATC
cloxacillin; systemic
6.2
19.7
34
57
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.5
19.7
148
681
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.2
19.5
211
1137
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
17.4
19.3
30
18
NA3SA
NOMESCO Finland
Lumbar spine X-ray examination in standing position
56.7
19.0
22
*
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
35.5
19.0
24
7
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
5.4
18.8
38
74
C03DA01
ATC
spironolactone; oral
2.6
18.8
127
554
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.6
18.8
122
522
T36
ICD-10 Finland
Poisoning by systemic antibiotics
5.1
18.7
40
82
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
18.6
168
837
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.2
18.6
211
1157
S22.0
ICD-10 Finland
Fracture of thoracic vertebra
6.8
18.4
29
44
B18.2
ICD-10 Finland
Chronic viral hepatitis C
14.1
18.4
31
23
M54.1
ICD-10 Finland
Radiculopathy
14.9
18.2
30
21
WX892
NOMESCO Finland
Monitored bed care
3.1
18.2
83
293
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
18.2
227
1289
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
5.3
18.1
37
73
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.6
18.1
121
525
NA3CM
NOMESCO Finland
Lumbar spine extensive MRI examination with 3 Tesla magnet
+∞
17.8
17
*
7227C
ICD-9 Finland
Intervertebral disk disorders, Intervertebral disk disorder with myelopathy[SYNDROMA ISCHIADICUM]
+∞
17.8
17
*
SPAT1211
SPAT
Application of soft bandage
3.1
17.7
79
276
N06AX11
ATC
mirtazapine; oral
2.1
17.6
234
1358
M25.5
ICD-10 Finland
Pain in joint
2.2
17.6
209
1163
N05CF01
ATC
zopiclone; oral
2.1
17.4
234
1364
ZXE00
NOMESCO Finland
One hour or less
2.0
17.3
282
1764
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
4.4
17.3
45
109
N06AX16
ATC
venlafaxine; oral
2.8
17.2
94
367
C08CA01
ATC
amlodipine; oral
2.0
17.1
307
1984
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.2
16.9
180
956
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.2
16.8
169
878
I50.0
ICD-10 Finland
Congestive heart failure
2.9
16.7
85
319
G99.2*M47.1
ICD-10 Finland
Spondylogenic compression of spinal cord
+∞
16.7
16
*
M47.1
ICD-10 Finland
Other spondylosis with myelopathy
+∞
16.7
16
*
J01MA14
ATC
moxifloxacin; systemic
2.9
16.7
86
325
P01BA02
ATC
hydroxychloroquine; oral
3.3
16.7
66
214
WX002
NOMESCO Finland
Sedation and analgesia
2.2
16.6
163
838
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
4.8
16.5
38
83
ZX120
NOMESCO Finland
Intravenous
2.9
16.3
86
329
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
16.3
242
1455
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
5.1
16.3
35
72
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.6
16.2
109
472
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
7.0
16.2
25
37
M03BC51
ATC
orphenadrine, combinations; systemic
2.2
16.2
170
897
E66.8
ICD-10 Finland
Other obesity
4.3
16.1
43
106
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.2
16.1
69
235
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.0
16.0
78
286
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.1
16.0
71
247
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
15.0
15.9
26
18
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.0
15.9
346
2370
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.7
15.9
52
149
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.1
15.8
34
70
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
61.5
15.8
18
*
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
7.4
15.8
23
32
N05BA04
ATC
oxazepam; oral
2.1
15.8
185
1018
D64.9
ICD-10 Finland
Anaemia, unspecified
2.5
15.7
106
460
M51.9
ICD-10 Finland
Intervertebral disc disorder, unspecified
+∞
15.7
15
*
72510
ICD-8 Finland
Displacement of intervertebral disk, Lumbalis cum prolapsu disci
+∞
15.7
15
*
ABC60
NOMESCO Finland
Decompression of cervical spinal cord
+∞
15.7
15
*
A03
ICPC
Fever
2.5
15.7
115
519
M01AH01
ATC
celecoxib; oral
2.4
15.7
122
566
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
3.3
15.6
61
196
B99
ICD-10 Finland
Other and unspecified infectious diseases
5.6
15.5
30
56
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
3.6
15.5
54
161
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.8
15.5
83
320
205
Kela drug reimbursment
Chronic hypertension
2.0
15.5
229
1371
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.2
15.4
149
759
L88
ICPC
Rheumatoid/seropositive arthritis
4.6
15.4
37
84
WX872
NOMESCO Finland
Intensive care
3.2
15.4
64
214
R5110, ,
SPAT
2.8
15.3
82
316
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.9
15.3
77
287
N05AH04
ATC
quetiapine; oral
2.4
15.3
116
531
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.8
15.2
47
129
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.4
15.1
123
581
R60.9
ICD-10 Finland
Oedema, unspecified
3.5
15.1
55
169
Z49.1
ICD-10 Finland
Extracorporeal dialysis
6.5
15.1
25
40
Z76.0
ICD-10 Finland
Issue of repeat prescription
2.1
15.1
185
1033
SPAT1301
SPAT
No procedures
2.0
15.1
223
1333
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.1
14.9
67
234
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
4.8
14.9
34
74
F11.25
ICD-10 Finland
Relationship caused by opiates continuously used
58.0
14.8
17
*
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
6.3
14.8
25
41
207
Kela drug reimbursment
Chronic arrhythmias
2.2
14.7
155
815
L04AX03
ATC
methotrexate; systemic
2.9
14.7
73
270
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.5
14.7
53
162
WZC00
NOMESCO Finland
Treatment plan or consultation
1.9
14.7
256
1617
NA3DM
NOMESCO Finland
Lumbar spine very extensive MRI examination with 3 Tesla magnet
+∞
14.6
14
*
A29
ICPC
General symptom/complaint other
2.4
14.5
116
543
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.5
14.5
52
158
Z72.2
ICD-10 Finland
Drug use
153.2
14.5
15
*
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
12.9
14.5
25
20
D07AC01
ATC
betamethasone; topical
1.9
14.5
257
1631
L84
ICPC
Back syndrome without radiat pain
4.2
14.4
39
97
NHQ40
NOMESCO Finland
Amputation of toe
6.1
14.4
25
42
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
27.9
14.3
19
7
M45
ICD-10 Finland
Ankylosing spondylitis
43.5
14.2
17
*
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
43.5
14.2
17
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.6
14.0
47
137
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.1
14.0
159
860
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
5.7
13.9
26
47
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.3
13.9
55
178
R02
ICPC
Shortness of breath/dyspnoea
2.4
13.9
110
513
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
3.4
13.8
51
158
WX402
NOMESCO Finland
General anaesthesia
2.1
13.8
159
864
S29
ICPC
Skin symptom/complaint other
2.1
13.8
151
805
WW200
NOMESCO Finland
Immunization
4.9
13.7
30
63
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.8
13.6
75
293
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
76.7
13.6
15
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.3
13.6
53
170
ZXA05
NOMESCO Finland
Left side
2.0
13.6
179
1021
KA1AE
NOMESCO Finland
Kidney ultrasound examination
4.5
13.5
33
76
W19
ICD-10 Finland
Unspecified fall
2.7
13.5
77
307
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
6.2
13.5
23
38
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.9
13.4
30
64
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
21.7
13.4
19
9
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.7
13.3
75
297
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
4.5
13.3
33
77
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.1
13.1
143
759
M01AH05
ATC
etoricoxib; oral
1.8
13.1
379
2781
J45.9
ICD-10 Finland
Asthma, unspecified
2.2
13.1
131
673
J01CA04
ATC
amoxicillin; systemic
2.1
13.1
526
4291
UKC02
NOMESCO Finland
Cystoscopy
2.1
13.0
139
732
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
6.3
13.0
22
36
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
5.2
13.0
27
54
SAA03
NOMESCO Finland
Extended examination of mouth
1.9
13.0
244
1566
ZXA00
NOMESCO Finland
Right side
2.0
12.9
193
1147
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
4.8
12.9
29
62
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.8
12.9
40
110
A02BC05
ATC
esomeprazole; systemic
1.9
12.8
262
1724
TQW80
NOMESCO Finland
Local dermatologic skincare
4.9
12.7
28
59
K07
ICPC
Swollen ankles/oedema
3.2
12.7
52
172
R33
ICD-10 Finland
Retention of urine
2.5
12.7
84
360
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.0
12.6
180
1052
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.0
12.5
56
195
NAW10
NOMESCO Finland
Reoperation for superficial infection in in surgery of spine or neck
+∞
12.5
12
*
NAU20
NOMESCO Finland
Removal of internal fixation device from spine or neck
+∞
12.5
12
*
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.1
12.5
142
764
E0000UV, ,
ATC
1.8
12.5
274
1839
M01AB05
ATC
diclofenac; systemic, rectal
1.8
12.5
411
3116
SPAT1260
SPAT
Consultation of another employee
2.2
12.5
127
656
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.9
12.4
59
213
SPAT1216
SPAT
Assessment of functional ability
2.2
12.4
126
650
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
3.5
12.4
44
133
EBA00
NOMESCO Finland
Extraction of tooth
1.8
12.3
242
1569
Z71.8
ICD-10 Finland
Other specified counselling
1.9
12.3
220
1386
SPAT1234
SPAT
Support of social functional capacity
3.2
12.3
50
165
SPAT1263
SPAT
Sampling
1.8
12.2
271
1823
WX213
NOMESCO Finland
Lower leg blockade
16.2
12.2
19
12
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.9
12.2
60
221
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.4
12.1
44
135
R53
ICD-10 Finland
Malaise and fatigue
2.0
12.1
168
972
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
4.1
12.1
33
83
SPAT1262
SPAT
Handing over of treatment supplies
2.1
12.0
140
760
S76
ICPC
Skin infection other
3.0
12.0
54
189
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
12.0
258
1718
K02.1
ICD-10 Finland
Caries of dentine
1.8
11.9
359
2636
N05BA01
ATC
diazepam; systemic, rectal
2.4
11.9
92
423
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.7
11.9
65
253
C09AA02
ATC
enalapril; systemic
2.0
11.8
161
924
P03
ICPC
Feeling depressed
3.0
11.8
53
185
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
9.9
11.8
23
24
XF600
NOMESCO Finland
Bloodpressure measurement
3.0
11.8
52
180
B01AF02
ATC
apixaban; oral
2.1
11.7
126
663
N05CF02
ATC
zolpidem; oral
2.2
11.7
112
563
E66.9
ICD-10 Finland
Obesity, unspecified
4.2
11.7
31
76
M01AB55
ATC
diclofenac, combinations; oral
3.1
11.7
50
170
NA2DG
NOMESCO Finland
Thoracal spine very extensive MRI examination with high intensity magnet
66.1
11.6
13
*
R06AE07
ATC
cetirizine; oral
1.8
11.6
253
1686
A40.1
ICD-10 Finland
Sepsis due to streptococcus, group B
23.4
11.6
16
7
9211
FHL
Exploration or removal of diskusprolapse
+∞
11.5
11
*
NAG66
NOMESCO Finland
Posterior interbody fusion of lumbar spine, 2 vertebrae
+∞
11.5
11
*
M46.0
ICD-10 Finland
Spinal enthesopathy
122.0
11.5
12
*
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
3.3
11.4
44
140
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.4
11.4
83
371
Y96.9
ICD-10 Finland
Unspecified type of accident
5.3
11.3
23
45
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
2.3
11.3
89
412
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
4.1
11.3
31
78
A04
ICPC
Weakness/tiredness general
2.2
11.2
109
551
WX730
NOMESCO Finland
Conventional respirator
5.7
11.2
21
38
N30.9
ICD-10 Finland
Cystitis, unspecified
3.1
11.2
48
163
XF400
NOMESCO Finland
ECG with 12 standard connections
2.1
11.2
126
674
L29
ICPC
Musculoskeletal sympt/complt other
2.6
11.2
66
267
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.8
11.2
56
208
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.7
11.2
337
2461
N06AB04
ATC
citalopram; systemic
2.0
11.2
131
712
127
Kela drug reimbursment
Transplant complication
5.4
11.1
22
42
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.5
11.1
73
312
Z49.0
ICD-10 Finland
Preparatory care for dialysis
10.3
11.1
21
21
L02
ICPC
Back symptom/complaint
2.7
11.0
63
251
M48.9
ICD-10 Finland
Spondylopathy, unspecified
44.1
10.9
13
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.0
10.9
136
756
K78
ICPC
Atrial fibrillation/flutter
2.4
10.8
78
347
L01
ICPC
Neck symptom/complaint
2.3
10.8
92
440
Z01.2
ICD-10 Finland
Dental examination
1.8
10.8
272
1881
L89
ICD-10 Finland
Decubitus ulcer and pressure area
4.5
10.8
26
59
XA402
NOMESCO Finland
ENMG
9.8
10.8
21
22
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
3.0
10.8
48
167
NA2AD
NOMESCO Finland
Thoracic spine CT examination
18.2
10.8
16
9
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.8
10.7
200
1268
C01AA05
ATC
digoxin; systemic
2.4
10.6
78
350
SPAT1252
SPAT
Overall medication plan or its review
2.7
10.6
61
244
J01CE08
ATC
benzathine benzylpenicillin; parenteral
10.3
10.6
20
20
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.2
10.6
100
500
F19.24
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances active addiction
111.7
10.4
11
*
M53.2
ICD-10 Finland
Spinal instabilities
111.7
10.4
11
*
ABC66
NOMESCO Finland
Decompression of lumbal spinal channel
+∞
10.4
10
*
WZC30
NOMESCO Finland
Teaching
2.0
10.4
123
669
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
4.1
10.4
29
74
L01BA01
ATC
methotrexate; systemic
4.4
10.4
26
61
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
5.3
10.4
21
41
R1250
NOMESCO Finland
Evaluation of functional capability
4.5
10.3
25
57
SPAT1231
SPAT
Assessment of adjustments needed in living environment
4.8
10.3
23
49
B01AB10
ATC
tinzaparin; parenteral
2.3
10.3
87
415
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
19.1
10.3
15
8
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
23.8
10.3
14
6
R06.2
ICD-10 Finland
Wheezing
3.5
10.3
36
108
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.8
10.3
31
84
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
4.2
10.2
27
66
Z02.7
ICD-10 Finland
Issue of medical certificate
2.7
10.2
57
224
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.1
10.2
44
150
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.3
10.2
86
410
G47.3
ICD-10 Finland
Sleep apnoea
1.9
10.2
157
935
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.4
10.2
72
318
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
5.4
10.2
20
38
WX290
NOMESCO Finland
Other blockage of nerve
1.7
10.1
272
1907
I50
ICD-10 Finland
Heart failure
3.6
10.1
34
99
WX882
NOMESCO Finland
High dependency care
3.9
10.1
30
80
N06AB10
ATC
escitalopram; oral
2.1
10.1
111
587
E000001, ,
ATC
2.0
10.1
126
698
L04AA06
ATC
mycophenolic acid; systemic
4.9
10.1
22
46
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
10.0
129
722
M35.3
ICD-10 Finland
Polymyalgia rheumatica
3.3
10.0
39
125
M50.3
ICD-10 Finland
Other cervical disc degeneration
14.9
10.0
16
11
M10.0
ICD-10 Finland
Idiopathic gout
3.1
10.0
42
141
I50.1
ICD-10 Finland
Left ventricular failure
2.7
10.0
54
209
Z2446
NOMESCO Finland
Social worker
2.7
10.0
54
209
B03XA02
ATC
darbepoetin alfa; parenteral
3.9
9.9
29
77
M00.0
ICD-10 Finland
Staphylococcal arthritis and polyarthritis
26.5
9.8
13
5
R52.0
ICD-10 Finland
Acute pain
4.0
9.8
28
73
M01AB01
ATC
indometacin; systemic, rectal
2.5
9.8
65
279
M01AE03
ATC
ketoprofen; systemic, rectal
1.7
9.7
230
1555
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
8.0
9.7
21
27
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
4.4
9.7
24
56
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.1
9.6
93
468
N19
ICD-10 Finland
Unspecified kidney failure
3.1
9.6
41
139
L14
ICPC
Leg/thigh symptom/complaint
2.5
9.6
62
262
J01AA02
ATC
doxycycline; systemic
1.8
9.6
496
4124
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
3.6
9.6
32
93
E66.01
ICD-10 Finland
Obesity due to excess calories
2.6
9.6
58
238
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
9.6
104
548
ZXA10
NOMESCO Finland
Bilateral
1.9
9.5
133
765
X58
ICD-10 Finland
Exposure to other specified factors
2.1
9.5
94
478
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.8
9.4
184
1175
R52.9
ICD-10 Finland
Pain, unspecified
2.4
9.4
68
303
NAG65
NOMESCO Finland
Anterior and posterior fusion of lumbar spine
+∞
9.4
9
*
M60.0
ICD-10 Finland
Infective myositis
+∞
9.4
9
*
ABC30
NOMESCO Finland
Decompression of cervical nerve roots
+∞
9.4
9
*
SPAT1240
SPAT
Therapeutic discussion
2.5
9.4
62
265
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.8
9.4
180
1144
V03AE01
ATC
polystyrene sulfonate; oral
5.0
9.4
20
41
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.6
9.3
30
85
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.7
9.3
49
187
E87.6
ICD-10 Finland
Hypokalaemia
3.3
9.3
35
110
R42
ICD-10 Finland
Dizziness and giddiness
1.8
9.2
155
946
K08.3
ICD-10 Finland
Retained dental root
2.4
9.2
63
274
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
7.9
9.2
20
26
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.8
9.2
190
1233
L16
ICPC
Ankle symptom/complaint
2.3
9.2
75
353
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.5
9.1
32
96
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
3.9
9.1
27
72
N05AH03
ATC
olanzapine; systemic
2.8
9.1
45
166
S11
ICPC
Skin infection post-traumatic
8.5
9.1
19
23
A10AB05
ATC
insulin aspart; parenteral
2.4
9.1
65
288
QDA10
NOMESCO Finland
Incision of skin of lower limb
11.7
9.1
16
14
A02BC03
ATC
lansoprazole; oral
1.8
9.1
179
1145
WX704
NOMESCO Finland
Intubation
2.6
9.0
54
220
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
4.3
9.0
23
55
R5599
NOMESCO Finland
Other rehabilitation service
4.3
9.0
23
55
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
18.9
9.0
13
7
M70.6
ICD-10 Finland
Trochanteric bursitis
2.3
8.9
73
343
N02AJ13
ATC
tramadol and paracetamol; systemic
5.0
8.9
19
39
ZZA00
NOMESCO Finland
Split skin graft
3.5
8.9
30
88
L13
ICPC
Hip symptom/complaint
1.9
8.9
123
705
P29
ICPC
Psychological sympt/compl other
2.9
8.9
41
146
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
2.7
8.8
46
175
N18.8
ICD-10 Finland
Other chronic renal failure
3.8
8.8
27
74
R81
ICPC
Pneumonia
3.2
8.8
34
109
H02AB07
ATC
prednisone; oral
2.1
8.8
92
478
N03AE01
ATC
clonazepam; systemic
2.9
8.7
41
147
A02BC01
ATC
omeprazole; systemic
1.8
8.7
171
1090
ZZH40
NOMESCO Finland
Substitute of bone
14.3
8.7
14
10
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.5
8.7
54
224
XX1CT
NOMESCO Finland
Other puncture with CT guidance
50.7
8.7
10
*
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.6
8.7
52
212
L04AD01
ATC
ciclosporin; systemic
4.9
8.6
19
40
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.0
8.6
39
137
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
8.4
8.6
18
22
R10.0
ICD-10 Finland
Acute abdomen
3.9
8.6
25
66
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.2
8.6
80
397
N30.0
ICD-10 Finland
Acute cystitis
2.0
8.6
100
540
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
3.8
8.5
26
71
P01AB01
ATC
metronidazole; oral, rectal
1.7
8.5
235
1643
A08
ICPC
Swelling
2.6
8.5
50
202
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.6
8.5
49
196
M02AA07
ATC
piroxicam; topical
1.7
8.5
218
1495
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
27.9
8.5
11
*
V03AE02
ATC
sevelamer; oral
20.3
8.5
12
6
S06.0
ICD-10 Finland
Concussion
2.2
8.5
76
371
I48.1
ICD-10 Finland
Persistent atrial fibrillation
2.7
8.5
44
167
R03AC02
ATC
salbutamol; inhalant
1.6
8.5
324
2457
NH1AD
NOMESCO Finland
Ankle and foot CT
4.4
8.5
21
49
KH1AD
NOMESCO Finland
CT of urinary organs
3.3
8.4
31
96
F11.24
ICD-10 Finland
Addiction-induced dependence caused by opiates active addiction
91.2
8.4
9
*
T14.5
ICD-10 Finland
Injury of blood vessel(s) of unspecified body region
13.0
8.4
14
11
M46.8
ICD-10 Finland
Other specified inflammatory spondylopathies
+∞
8.3
8
*
AB5BT
NOMESCO Finland
Blockage of nerv root with X-ray guidance
+∞
8.3
8
*
N05BA12
ATC
alprazolam; oral
2.3
8.3
66
306
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
8.7
8.3
17
20
G54.0
ICD-10 Finland
Brachial plexus disorders
9.6
8.3
16
17
QCB05
NOMESCO Finland
Revision of wound of skin of upper limb
9.6
8.3
16
17
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.3
8.3
65
300
WX204
NOMESCO Finland
Axillary plexus blockaced
3.4
8.3
29
87
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
8.3
238
1680
L99
ICPC
Musculoskeletal disease other
4.3
8.2
21
50
GD1AD
NOMESCO Finland
Thorax CT examination
2.4
8.2
56
243
M70.2
ICD-10 Finland
Olecranon bursitis
3.2
8.2
32
103
N03AX09
ATC
lamotrigine; oral
3.7
8.2
26
73
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
3.3
8.2
31
98
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
8.2
422
3428
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.3
8.2
30
93
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
3.9
8.1
24
64
M01AC06
ATC
meloxicam; systemic, rectal
1.7
8.1
214
1475
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
4.1
8.1
22
55
D07BC01
ATC
betamethasone and antiseptics; topical
2.1
8.1
86
448
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
11.9
8.1
14
12
SFA10
NOMESCO Finland
One-surface restoration
1.6
8.1
320
2437
SPAT1265
SPAT
Breathalyser
9.1
8.1
16
18
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
4.2
8.0
21
51
J05AB11
ATC
valaciclovir; oral
2.0
8.0
93
500
M43.0
ICD-10 Finland
Spondylolysis
22.3
8.0
11
5
D07AD01
ATC
clobetasol; topical
1.9
8.0
103
575
C09BA02
ATC
enalapril and diuretics; systemic
2.3
8.0
65
305
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.2
7.9
69
333
S61.9
ICD-10 Finland
Open wound of wrist and hand, part unspecified
3.7
7.9
25
70
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.7
7.9
18
39
196
Kela drug reimbursment
Paricalcitol and cinacalcet
13.2
7.9
13
10
L15
ICPC
Knee symptom/complaint
1.7
7.9
154
979
TK810
NOMESCO Finland
Hemofiltration
9.6
7.8
15
16
M05BA04
ATC
alendronic acid; oral
2.3
7.8
62
288
H02AB04
ATC
methylprednisolone; systemic
2.0
7.8
92
498
N03AF02
ATC
oxcarbazepine; oral
3.7
7.8
24
66
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.5
7.8
50
211
WX202
NOMESCO Finland
Supraclavicular plexus blockade
6.5
7.8
19
30
R52.2
ICD-10 Finland
Other chronic pain
4.0
7.8
22
57
F19.29
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances UNS
15.2
7.7
12
8
A40.9
ICD-10 Finland
Streptococcal sepsis, unspecified
15.2
7.7
12
8
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
2.1
7.7
80
413
TAB20
NOMESCO Finland
Epidural puncture
45.5
7.7
9
*
SPAT1272
SPAT
Drug screening
45.5
7.7
9
*
A99
ICPC
Disease/condition unspecnature/site
2.1
7.7
77
392
R05
ICD-10 Finland
Cough
1.8
7.7
135
830
K92.1
ICD-10 Finland
Melaena
2.5
7.7
48
200
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.1
7.7
31
102
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.3
7.7
56
251
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
8.2
7.6
16
20
ZXM20
NOMESCO Finland
Intraoperative use of computerised tomography
18.6
7.6
11
6
T90
ICPC
Diabetes non-insulin dependent
1.7
7.6
182
1220
R04.0
ICD-10 Finland
Epistaxis
2.2
7.6
66
318
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
2.5
7.6
48
201
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
25.3
7.6
10
*
F19.25
ICD-10 Finland
Addiction caused by several drugs in combination and by other psychoactive substances continuously used
25.3
7.6
10
*
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
3.9
7.6
22
58
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
3.9
7.6
22
58
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
9.0
7.6
15
17
B01AB04
ATC
dalteparin; parenteral
2.8
7.6
37
136
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.0
7.5
33
114
I48.2
ICD-10 Finland
Chronic atrial fibrillation
2.5
7.5
48
202
X57
ICD-10 Finland
Unspecified privation
3.7
7.5
23
63
Z50.1
ICD-10 Finland
Other physical therapy
2.7
7.5
40
154
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
3.6
7.5
24
68
PD4AC
NOMESCO Finland
Arterigography of lower extremity with X-ray
4.5
7.5
18
41
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
7.5
182
1226
QCA10
NOMESCO Finland
Incision of skin of upper limb
81.0
7.4
8
*
M51.8
ICD-10 Finland
Other specified intervertebral disc disorders
81.0
7.4
8
*
IFC01, ,
SPAT
81.0
7.4
8
*
R11
ICD-10 Finland
Nausea and vomiting
2.3
7.4
57
261
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
7.4
244
1769
SPAT1275
SPAT
Drug rehabilitation and replacement therapy of opioid-dependent person
13.5
7.4
12
9
NB1AT
NOMESCO Finland
Puncture of shoulder with ultrasound guidance
13.5
7.4
12
9
A12AA04
ATC
calcium carbonate; oral
4.1
7.4
20
50
N05AF03
ATC
chlorprothixene; systemic
4.1
7.4
20
50
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.7
7.4
179
1204
SPAT1153
SPAT
Removal of sutures
1.6
7.4
200
1384
ACC51
NOMESCO Finland
Release of median nerve
2.5
7.3
45
186
U05
ICPC
Urination problems other
2.5
7.3
44
180
N18.3
ICD-10 Finland
Chronic kidney disease, stage 3
3.5
7.3
25
74
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
3.4
7.3
26
79
7245A
ICD-9 Finland
Other and unspecified disorders of back, Backache, unspecified
+∞
7.3
7
*
72880
ICD-8 Finland
Vertebrogenic pain syndrome, Radicula syndrome of lower limbs
+∞
7.3
7
*
NA3BD
NOMESCO Finland
Extensive lumbar spine and sacrum CT examination
+∞
7.3
7
*
72870
ICD-8 Finland
Vertebrogenic pain syndrome, Lumbalgia
+∞
7.3
7
*
NAG53
NOMESCO Finland
Posterior or lateral fusion of thoracic spine with fixation, more than 3 vertebraea
+∞
7.3
7
*
SPAT1172
SPAT
Guidance concerning hydration
3.9
7.3
21
55
I44.2
ICD-10 Finland
Atrioventricular block, complete
3.0
7.3
32
111
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
4.4
7.3
18
42
F13.22
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent but uses substitute intermittent medication
15.9
7.2
11
7
KMAK, ,
NOMESCO Finland
1.6
7.2
283
2134
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.5
7.2
47
200
D64.8
ICD-10 Finland
Other specified anaemias
4.0
7.2
20
51
S10
ICPC
Boil/carbuncle
2.5
7.2
45
188
A11CC03
ATC
alfacalcidol; systemic
3.3
7.2
26
80
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.9
7.2
34
123
A41.2
ICD-10 Finland
Sepsis due to unspecified staphylococcus
30.4
7.2
9
*
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.3
7.2
53
239
SFA30
NOMESCO Finland
Three-surface restoration
1.6
7.2
258
1908
RD210, ,
NOMESCO Finland
6.7
7.1
17
26
R51.80
ICD-10 Finland
Headache
2.0
7.1
80
425
M16.1
ICD-10 Finland
Other primary coxarthrosis
2.0
7.1
82
440
Y94.0
ICD-10 Finland
Accident at home
4.1
7.1
19
47
SAA02
NOMESCO Finland
Basic examination of mouth
1.6
7.1
376
3027
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.2
7.1
62
300
PD4AD
NOMESCO Finland
CT of lower extremity arteries
8.9
7.1
14
16
SFA20
NOMESCO Finland
Two-surface restoration
1.5
7.1
337
2651
U14
ICPC
Kidney symptom/complaint
3.9
7.0
20
52
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.2
7.0
60
288
F51.0
ICD-10 Finland
Nonorganic insomnia
2.0
6.9
82
444
M05BB03
ATC
alendronic acid and colecalciferol; oral
4.0
6.9
19
48
Z49.2
ICD-10 Finland
Other dialysis
7.6
6.9
15
20
XKD00
NOMESCO Finland
Uroflowmetry
1.7
6.9
129
807
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
3.5
6.9
23
67
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
3.3
6.9
25
77
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.8
6.9
34
126
P01
ICPC
Feeling anxious/nervous/tense
2.4
6.8
47
205
A10BH05
ATC
linagliptin; oral
2.4
6.8
47
205
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.5
6.8
43
180
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.7
6.8
37
144
J01CF01
ATC
dicloxacillin; systemic
9.4
6.8
13
14
M01AE01
ATC
ibuprofen; systemic, rectal
1.7
6.8
552
4889
A10AE04
ATC
insulin glargine; parenteral
2.0
6.8
76
404
E66.00
ICD-10 Finland
Metabolic syndrome
2.4
6.8
44
187
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
2.9
6.8
31
110
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.9
6.8
31
110
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.8
6.8
34
127
PB1BC
NOMESCO Finland
Extensive angiography of upper extremity with X-ray
40.5
6.8
8
*
T91.3
ICD-10 Finland
Sequelae of injury of spinal cord
40.5
6.8
8
*
P15
ICPC
Chronic alcohol abuse
3.3
6.8
25
78
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.6
6.7
226
1639
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.7
6.7
36
139
L12
ICPC
Hand/finger symptom/complaint
1.8
6.7
99
577
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.1
6.7
27
89
Z2221
NOMESCO Finland
Medical doctor
1.6
6.7
169
1145
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
3.2
6.7
26
84
S91.1
ICD-10 Finland
Open wound of toe(s) without damage to nail
5.6
6.6
18
33
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
6.0
6.6
17
29
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
7.9
6.6
14
18
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
2.6
6.6
38
152
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
3.5
6.6
22
64
K99
ICPC
Cardiovascular disease other
3.3
6.6
24
74
L04AK01
ATC
leflunomide; oral
12.4
6.6
11
9
R03DC03
ATC
montelukast; oral
1.9
6.6
85
474
R4120
NOMESCO Finland
Occupational therapy
2.4
6.6
45
196
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.2
6.6
58
282
L04AB04
ATC
adalimumab; parenteral
6.9
6.5
15
22
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
5.4
6.5
18
34
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.8
6.5
111
676
SPAT1281
SPAT
Other administrative function
2.2
6.5
54
256
N06AX12
ATC
bupropion; oral
2.7
6.5
34
130
RS221, ,
NOMESCO Finland
5.8
6.5
17
30
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
5.8
6.5
17
30
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.4
6.5
23
70
103
Kela drug reimbursment
Diabetes, insulin-treated
1.6
6.5
198
1404
J01CE02
ATC
phenoxymethylpenicillin; oral
1.5
6.4
408
3384
G06.2
ICD-10 Finland
Extradural and subdural abscess, unspecified
70.5
6.4
7
*
M99.3
ICD-10 Finland
Osseous stenosis of neural canal
70.5
6.4
7
*
ND1AA
NOMESCO Finland
Wrist X-ray examination
2.2
6.4
51
237
J01FA06
ATC
roxithromycin; oral
1.5
6.4
232
1707
G04CA02
ATC
tamsulosin; oral
1.6
6.4
197
1398
Z29
ICPC
Social problem NOS
4.1
6.4
17
42
L03.9
ICD-10 Finland
Cellulitis, unspecified
4.1
6.4
17
42
SPAT1304
SPAT
Counselling and guidance related to ageing
2.1
6.4
62
313
N07BB01
ATC
disulfiram; oral
2.8
6.4
31
114
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
3.7
6.4
20
56
L04AB01
ATC
etanercept; parenteral
8.3
6.4
13
16
N18.0
ICD-10 Finland
End-stage renal disease
6.0
6.3
16
27
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
3.4
6.3
22
66
M54.0
ICD-10 Finland
Panniculitis affecting regions of neck and back
11.2
6.3
11
10
PF1BT
NOMESCO Finland
Extensive PTA of arteries of knee, lower leg and ankle
9.4
6.3
12
13
J01DA01
ATC
[U] cefalexin
1.5
6.3
366
2975
SPAT1307
SPAT
Psychosocial counselling and guidance
3.1
6.3
26
87
C09CA01
ATC
losartan; oral
1.6
6.3
180
1255
L20
ICPC
Joint symptom/complaint NOS
2.9
6.3
28
98
A40.0
ICD-10 Finland
Sepsis due to streptococcus, group A
18.2
6.3
9
5
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
18.2
6.3
9
5
A49
ICD-10 Finland
Bacterial infection of unspecified site
18.2
6.3
9
5
Z3229
NOMESCO Finland
Other healthcare associate professional
2.1
6.3
62
315
71700, ,
ICD-8 Finland
+∞
6.3
6
*
M96.1
ICD-10 Finland
Postlaminectomy syndrome, not elsewhere classified
+∞
6.3
6
*
TNG10
NOMESCO Finland
Puncture of knee
7.1
6.2
14
20
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
2.7
6.2
32
121
F11.29
ICD-10 Finland
Addiction caused by opiates UNS
26.9
6.2
8
*
M01AB51
ATC
indometacin, combinations; oral, rectal
3.7
6.2
19
52
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.7
6.2
140
919
P16
ICPC
Acute alcohol abuse
5.1
6.2
18
36
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.3
6.2
23
72
NA3AA, ,
SPAT
3.3
6.2
23
72
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.4
6.2
22
67
S22.4
ICD-10 Finland
Multiple fractures of ribs
3.5
6.2
21
62
W22
ICD-10 Finland
Striking against or struck by other object(s)
2.5
6.2
39
164
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
2.7
6.1
32
122
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
7.8
6.1
13
17
UJF30
NOMESCO Finland
Ileoscopy through colon
2.0
6.1
68
360
F10.25
ICD-10 Finland
Alcohol dependence continuous use
3.8
6.1
18
48
J02AC01
ATC
fluconazole; systemic
1.6
6.1
187
1323
C08CA02
ATC
felodipine; oral
2.0
6.1
70
375
-50
ICPC
Medication/prescr/renewal
2.8
6.1
30
111
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
2.8
6.1
30
111
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
12.7
6.1
10
8
RJ410, ,
NOMESCO Finland
12.7
6.1
10
8
D07AB08
ATC
desonide; topical
2.0
6.1
68
361
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
3.7
6.1
19
53
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.9
6.1
81
457
D02AE01
ATC
carbamide; topical
2.3
6.1
44
197
R20.2
ICD-10 Finland
Paraesthesia of skin
2.5
6.0
36
147
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
6.0
119
754
N06AX26
ATC
vortioxetine; oral
2.4
6.0
40
172
K02.9
ICD-10 Finland
Dental caries, unspecified
3.9
6.0
17
44

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
503
1768
8.40
148.08
11.1
4.4
—
—
—
0
0
324
816
6.75
133.29
3.2
2.1
—
—
—
0
0
539
2811
5.69
80.08
13.6
6.0
0.04
0.04
e9/l
1.05
494
2379
538
2808
5.65
79.67
13.5
6.0
0.66
0.61
e9/l
4.32
493
2368
539
2853
5.55
77.38
13.8
6.1
1.65
1.91
e9/l
3.64
500
2481
540
2890
5.48
75.65
14.3
6.3
0.21
0.19
e9/l
1.28
500
2480
143
275
6.34
74.13
2.5
1.9
3.22
2.36
ug/l
0.13
135
249
50
19
28.36
73.19
1.3
1.1
281.30
284.19
iu/ml
0.01
50
19
504
2630
4.70
71.05
14.1
6.2
9.21
9.22
%
0.03
494
2455
503
2630
4.66
70.48
14.2
6.1
2.99
2.85
%
0.67
493
2460
498
2629
4.48
67.70
14.4
6.2
0.69
0.67
%
0.36
489
2454
410
1895
4.00
67.66
12.9
6.0
—
—
—
0
0
502
2667
4.52
67.59
14.2
6.2
23.36
26.40
%
8.25
493
2527
496
2615
4.45
67.45
14.1
6.1
61.16
58.23
%
6.24
488
2498
534
3048
4.70
62.99
10.7
7.2
11.39
12.51
umol/l
1.38
526
2908
546
3177
4.88
62.46
18.5
9.9
4.63
4.17
e9/l
4.43
506
2727
513
2872
4.36
61.52
26.8
16.8
1.40
1.32
inr
2.44
451
2414
243
841
3.96
60.21
10.5
6.3
1.11
1.03
mmol/l
2.70
234
778
261
957
3.83
59.28
4.3
2.6
2.16
2.25
g/l
1.26
249
892
517
2965
4.26
58.50
14.8
7.7
1.20
1.21
mmol/l
2.12
471
2535
478
2604
3.92
58.36
8.6
5.2
32.05
35.17
g/l
20.47
466
2441
270
1022
3.75
58.32
4.4
2.6
9.83
12.45
umol/l
7.72
260
951
247
888
3.82
57.51
4.2
2.6
18.90
22.27
%
2.76
240
829
177
511
4.35
56.00
3.0
2.7
64.94
66.38
g/l
1.49
172
477
264
1007
3.68
55.98
4.6
3.6
0.81
0.82
mmol/l
0.83
255
954
155
415
4.56
53.97
2.8
2.3
—
—
—
0
0
207
700
3.83
52.12
2.3
1.7
—
—
—
0
0
190
608
3.97
51.79
14.0
7.4
13.52
10.58
mmol/l
4.59
183
575
191
630
3.84
49.62
3.0
1.6
—
—
—
0
0
327
1536
3.21
47.87
3.1
2.2
3.25
2.92
mg/l
1.46
295
1304
101
208
5.54
47.80
3.4
3.2
56.00
90.83
mg/l
0.61
83
176
101
208
5.54
47.80
3.4
3.2
39.31
60.21
mg/l
0.67
82
179
460
2669
3.31
45.97
13.3
6.8
1.20
1.21
mmol/l
2.30
446
2459
341
1679
3.10
45.34
5.2
3.0
—
—
—
0
0
373
1937
3.09
45.00
4.7
3.3
51.93
106.22
e6/l
0.80
312
1478
347
1736
3.07
44.67
3.8
2.5
55.18
68.01
u/l
1.59
339
1607
367
1928
3.00
42.67
5.3
3.4
2569.50
1611.13
ng/l
2.25
343
1692
183
644
3.53
42.46
7.3
3.6
5.77
5.81
kpa
0.18
178
622
396
2174
3.01
42.37
5.7
3.8
110.66
152.37
e6/l
0.42
313
1552
92
194
5.34
42.24
3.4
2.8
1.93
4.49
ratio
0.74
53
114
183
647
3.52
42.12
7.0
3.6
7.37
7.38
ph
0.71
124
372
547
3628
3.77
41.70
7.8
4.3
1176.33
2229.49
e6/l
—
7
59
200
758
3.34
41.07
3.1
2.7
1.88
1.77
%
0.86
188
681
177
624
3.50
40.79
7.3
3.6
1.56
1.87
mmol/l
0.47
158
524
329
1660
2.93
40.69
4.6
3.2
0.59
0.51
e6/l
0.22
268
1219
527
3441
3.49
40.65
9.9
5.2
6.88
6.84
mmol/l
0.20
520
3293
604
4318
5.05
40.36
19.5
8.4
94.20
80.06
u/l
10.82
591
4077
307
1511
2.90
39.49
4.5
2.9
378.76
363.45
umol/l
1.28
273
1330
337
1743
2.88
39.47
2.9
2.1
333.47
285.02
u/l
0.13
327
1641
347
1842
2.83
38.36
3.6
2.5
—
—
—
0
0
168
595
3.43
38.21
3.2
2.8
70.73
68.16
e9/l
0.37
116
435
430
2568
2.88
37.61
3.9
2.8
—
—
estimate
—
0
0
335
1768
2.79
37.12
8.8
4.3
7.40
7.40
ph
1.78
259
1264
308
1560
2.80
36.92
4.6
3.1
—
0.00
estimate
—
0
9
158
557
3.40
36.02
12.1
9.7
—
—
—
0
0
275
1332
2.81
35.68
3.6
2.6
5.24
5.21
e6/l
0.01
260
1215
393
2296
2.72
34.91
5.3
3.2
6.31
6.20
ph
1.11
207
1273
408
2437
2.72
34.53
4.8
2.9
171.09
145.90
ug/l
1.54
387
2248
280
1401
2.72
33.68
3.4
2.5
—
—
—
0
0
312
1649
2.67
33.59
14.2
6.4
—
—
—
0
0
173
673
3.12
33.25
1.5
1.3
323.56
441.62
titre
1.02
45
148
70
143
5.35
33.11
1.3
1.7
—
—
—
0
0
133
444
3.49
32.84
3.2
3.0
11.67
11.02
g/l
0.55
124
409
108
314
3.91
32.75
1.6
1.9
1.73
1.54
g/l
1.03
100
277
453
2896
2.74
32.70
6.2
3.6
0.00
4.96
estimate
0.80
105
637
170
662
3.10
32.55
10.3
9.0
95.95
95.20
%
1.29
164
646
182
738
3.01
32.43
9.9
8.5
11.92
11.97
kpa
0.04
174
719
182
738
3.01
32.43
9.9
8.5
5.27
5.14
kpa
0.88
174
720
174
690
3.06
32.24
1.7
1.5
—
—
—
0
0
181
736
3.00
32.05
10.0
8.5
1.29
1.07
mmol/l
0.33
156
617
448
2866
2.70
31.98
6.2
3.6
0.00
0.00
estimate
-0.00
106
631
181
737
2.99
31.97
10.3
8.5
7.40
7.42
ph
1.52
106
413
333
1854
2.58
31.70
4.8
3.3
35.21
34.68
u/l
0.10
316
1755
450
2905
2.67
31.19
6.2
3.6
0.03
0.52
estimate
0.48
100
595
405
2500
2.57
30.60
26.5
11.7
0.00
0.00
e9/l
0.56
350
2032
319
1770
2.53
30.19
2.0
1.7
17.54
20.14
nmol/l
2.18
294
1482
81
211
4.23
28.43
1.3
1.3
—
—
—
0
0
142
539
3.07
28.08
6.5
2.9
4.98
4.50
kpa
1.50
137
522
227
1106
2.59
27.84
2.9
1.6
1.47
1.53
mg/l
0.13
191
878
158
645
2.90
27.36
3.0
2.8
9.71
8.69
umol/l
0.22
143
578
64
143
4.84
27.22
2.7
2.9
30.00
34.83
umol/l
1.39
59
132
147
581
2.96
26.97
2.6
2.2
0.18
0.20
g/l
2.31
137
540
63
141
4.83
26.73
1.7
1.4
48081.43
23592.84
e6/l
0.51
42
94
211
1018
2.57
26.16
4.1
2.9
1.43
1.00
e6/l
0.74
131
541
384
2433
2.35
25.64
3.3
2.3
76.66
78.04
nmol/l
0.41
358
2155
213
1050
2.51
25.08
2.3
1.8
1234.29
1144.60
nmol/l
0.55
175
789
32
39
8.57
24.56
9.8
2.9
—
—
—
0
0
356
2224
2.28
24.04
6.8
3.9
49.97
90.59
ng/l
0.66
304
1697
131
518
2.90
23.81
2.9
2.3
28.71
125.23
u/l
0.54
110
447
133
537
2.84
23.22
2.2
1.6
—
—
—
0
0
117
441
3.00
23.14
5.8
4.0
127.61
92.85
ng/l
2.00
107
378
195
961
2.45
22.65
4.2
3.0
3.33
1.85
e6/l
1.11
113
482
222
1163
2.36
22.45
4.2
2.9
495.77
546.53
mosm/kgh2o
3.66
203
1015
394
2627
2.21
21.92
2.7
2.2
95.13
95.10
pmol/l
0.00
241
1398
639
5354
5.18
21.68
56.2
16.3
37.83
28.14
mg/l
10.43
621
4447
144
632
2.63
21.23
2.3
1.6
—
—
—
0
0
162
754
2.51
21.13
1.4
1.3
14.64
19.36
u/ml
0.29
58
271
45
96
4.95
20.14
1.7
1.3
—
—
—
0
0
143
642
2.56
20.03
4.8
3.5
5.74
4.20
e9/l
0.70
129
550
37
69
5.62
19.21
9.9
3.2
—
—
—
0
0
32
52
6.41
19.08
1.5
1.4
76.72
66.71
%
0.75
25
38
212
1158
2.22
18.87
5.1
3.9
752.37
435.74
ng/l
0.48
183
965
103
406
2.82
18.59
5.7
3.8
7.40
7.42
ph
2.30
95
347
51
130
4.16
18.30
5.7
4.0
—
—
—
0
0
35
65
5.63
18.25
1.1
1.2
—
—
—
0
0
63
188
3.60
18.12
4.0
3.0
2.15
1.72
mg/l
2.06
56
172
119
515
2.59
17.84
3.1
2.2
8.47
8.15
ug/l
0.06
104
456
163
818
2.31
17.65
1.5
1.3
64.23
44.97
iu/ml
0.49
65
260
38
79
5.04
17.51
1.6
1.5
132.45
147.62
au/ml
0.23
13
20
94
364
2.84
17.50
7.5
4.7
—
—
—
0
0
37
77
5.03
17.03
1.9
2.6
1.62
1.10
g/24h
0.63
22
44
307
1989
2.00
16.93
4.3
3.7
2.34
2.35
mmol/l
0.67
280
1799
113
493
2.55
16.60
5.2
4.3
0.77
0.52
%
0.83
52
162
92
366
2.75
16.24
2.0
1.5
—
—
—
0
0
39
90
4.54
15.88
1.6
1.5
—
—
—
0
0
115
517
2.48
15.82
5.0
4.4
0.81
0.93
%
0.27
54
168
98
408
2.64
15.81
6.2
2.9
117.60
127.32
g/l
3.86
98
397
110
486
2.51
15.70
2.4
2.2
388.24
393.66
nmol/l
0.08
105
455
37
83
4.66
15.59
1.2
1.0
—
—
—
0
0
111
496
2.48
15.45
2.9
2.2
0.00
0.03
estimate
0.50
25
95
111
498
2.47
15.31
5.3
4.9
0.04
0.19
%
1.05
46
139
47
133
3.72
14.59
1.4
1.2
—
—
—
0
0
109
497
2.42
14.48
4.9
4.5
0.06
0.13
%
0.76
47
149
39
97
4.21
14.45
1.4
1.4
33.59
29.98
g/l
0.82
31
87
21
11
19.66
14.30
1.7
1.1
—
—
—
0
0
313
2125
1.89
14.29
5.3
3.5
6.69
7.60
mmol/l
3.08
275
1778
62
213
3.11
14.22
2.4
1.5
0.35
0.39
mg/l
0.16
38
110
34
77
4.60
14.17
9.7
2.1
—
—
—
0
0
40
103
4.07
14.15
6.3
3.7
16.08
9.27
pmol/l
1.15
40
103
43
118
3.83
13.95
8.2
4.2
2.59
2.62
mmol/l
0.03
33
80
37
92
4.20
13.71
10.3
2.0
—
—
—
0
0
171
958
2.05
13.65
2.0
1.5
3.30
2.61
g/l
2.50
127
584
35
84
4.34
13.57
1.1
1.0
—
—
—
0
0
251
1613
1.89
13.38
7.1
3.6
0.00
0.01
estimate
0.96
89
570
70
268
2.80
13.23
3.3
2.2
0.00
0.01
estimate
0.49
20
75
25
46
5.61
13.15
1.5
1.2
15031.43
145923.59
e6/l
0.82
14
27
312
2159
1.83
13.05
6.5
3.6
0.01
0.03
estimate
0.59
86
511
34
83
4.26
12.90
1.4
1.6
—
—
—
0
0
34
83
4.26
12.90
1.4
1.6
—
—
—
0
0
34
83
4.26
12.90
1.4
1.6
—
—
—
0
0
34
83
4.26
12.90
1.4
1.6
—
—
—
0
0
38
101
3.93
12.89
10.1
2.0
—
—
—
0
0
60
215
2.97
12.79
3.7
3.2
514.66
315.16
mg/l
0.53
41
93
195
1169
1.94
12.72
7.4
4.8
—
—
—
0
0
49
157
3.29
12.60
3.1
3.5
0.83
0.80
nmol/l
0.18
43
133
37
99
3.90
12.43
1.5
1.2
316.92
296.77
u/ml
0.14
25
54
37
100
3.86
12.26
10.4
2.0
—
—
—
0
0
303
2111
1.79
12.12
5.1
4.3
22.80
8.77
mg/mmol
2.65
220
1363
56
199
2.98
12.11
2.0
2.0
12.56
7.34
iu/ml
—
9
46
37
101
3.82
12.09
11.0
1.6
—
—
—
0
0
37
101
3.82
12.09
10.6
2.0
—
—
—
0
0
104
506
2.25
11.80
4.9
3.1
310.68
227.77
ng/l
0.83
94
468
495
4016
1.89
11.65
4.6
4.0
14.93
14.98
pmol/l
0.16
458
3622
34
90
3.93
11.60
3.8
2.7
4.63
4.47
e9/l
0.19
34
90
39
114
3.57
11.56
1.5
1.2
—
—
—
0
0
133
722
2.05
11.38
1.3
1.2
—
—
—
0
0
29
69
4.35
11.38
1.8
1.4
—
—
—
0
0
27
62
4.50
11.07
1.4
2.0
—
—
—
0
0
60
233
2.73
11.03
1.3
1.2
—
—
—
0
0
293
2069
1.74
10.84
4.5
3.5
108.77
53.67
mg/l
2.05
230
1362
637
5750
3.19
10.56
27.4
12.0
26.52
26.17
u/l
0.18
627
5557
620
5538
2.60
10.16
39.5
15.0
—
—
—
0
0
200
1294
1.78
9.86
2.1
1.8
458.31
44877089.77
pmol/l
1.68
169
1054
30
83
3.74
9.64
1.5
1.3
41754.95
1415.68
e6/l
0.57
19
57
188
1206
1.78
9.49
6.6
3.7
1.02
1.02
kg/l
0.05
138
811
28
75
3.85
9.41
1.5
1.4
—
—
—
0
0
182
1161
1.78
9.35
4.0
3.4
2.48
2.46
mmol/l
1.70
160
1053
446
3620
1.69
9.20
5.9
3.1
78.23
53.65
u/l
5.17
431
3359
643
5905
3.21
8.92
71.6
25.0
253.90
240.76
e9/l
4.40
638
5758
36
120
3.11
8.71
4.5
2.7
62.25
58.00
%
1.31
36
120
26
70
3.82
8.69
1.6
1.3
34693.47
62073.58
e6/l
0.26
15
36
568
4975
1.93
8.62
5.9
4.9
2.58
2.01
mu/l
0.43
539
4489
27
80
3.47
7.88
1.4
1.3
50.68
55.33
mmol/l
0.26
22
66
16
19
8.60
7.84
1.2
1.2
2.50
1.75
%
—
8
8
162
1050
1.72
7.69
1.4
1.3
2.82
1.49
u/ml
0.34
42
273
39
147
2.76
7.61
3.5
2.4
61.25
63.15
%
0.17
39
147
62
292
2.24
7.56
7.0
3.9
—
—
—
0
0
29
93
3.21
7.49
3.0
2.3
—
—
—
0
0
56
259
2.27
7.13
2.8
1.9
—
—
—
0
0
35
130
2.79
7.03
1.3
1.1
—
—
—
0
0
219
1565
1.59
7.00
5.7
3.2
0.01
0.08
estimate
0.59
82
475
585
5264
1.88
6.90
8.5
6.7
41.16
39.97
mmol/mol
2.06
557
4873
79
424
1.98
6.86
5.8
3.1
—
—
—
0
0
285
2175
1.54
6.77
2.2
2.3
—
—
—
0
0
40
164
2.53
6.64
1.1
1.2
—
256.00
—
0
5
86
483
1.90
6.53
10.1
3.7
1.21
1.22
mmol/l
0.87
81
404
38
154
2.56
6.47
2.8
2.4
118.81
128.35
g/l
1.18
31
124
17
32
5.42
6.19
1.1
1.6
—
—
—
0
0
16
28
5.83
6.17
1.0
1.0
—
—
—
0
0
39
167
2.42
5.93
4.4
3.7
1.52
2.06
index
0.44
21
94
14
22
6.47
5.88
1.0
1.0
—
—
—
0
0
49
235
2.17
5.74
1.6
1.6
—
—
—
0
0
30
115
2.68
5.72
1.1
1.1
—
—
—
0
0
12
16
7.61
5.65
2.1
3.8
0.59
0.61
mmol/l
0.21
12
16
28
106
2.71
5.47
1.2
1.9
—
—
—
0
0
23
78
3.02
5.46
1.4
1.6
—
—
—
0
0
16
33
4.94
5.46
1.3
2.3
—
—
—
0
0
587
5370
1.75
5.43
6.1
5.3
6.20
6.05
mmol/l
1.68
548
4846
20
63
3.24
5.35
2.5
3.8
—
—
—
0
0
268
2101
1.46
5.22
5.6
3.8
—
0.86
—
0
7
24
86
2.86
5.19
2.0
2.6
29.96
32.74
pg
1.59
24
86
93
575
1.72
5.14
8.3
4.6
7.38
7.35
ph
1.74
79
411
64
355
1.89
5.06
1.1
1.2
—
—
—
0
0
106
683
1.66
5.02
3.8
4.8
15.28
26.24
ug/l
0.36
90
559
14
28
5.08
4.96
1.5
1.3
—
—
—
0
0
12
20
6.09
4.93
1.8
1.6
—
—
—
0
0
29
119
2.50
4.86
1.3
1.5
87.36
217.21
e6/l
0.41
22
89
16
47
3.46
4.77
2.0
2.3
794.00
1075.04
mg
0.43
16
47
31
133
2.40
4.73
1.1
1.2
—
—
—
0
0
51
270
1.96
4.64
3.0
3.6
4.18
4.39
pmol/l
0.79
46
233
23
87
2.70
4.53
1.3
1.7
0.88
1.03
g/l
0.21
16
68
28
118
2.43
4.45
1.2
1.4
128.00
44.05
e6/l
0.29
19
85
19
66
2.93
4.36
1.1
1.1
—
—
—
0
0
16
50
3.25
4.36
1.4
1.2
9.35
7.81
g/l
—
9
33
16
50
3.25
4.36
1.4
1.2
—
—
—
0
0
16
50
3.25
4.36
1.4
1.2
0.58
0.61
g/l
—
9
33
16
50
3.25
4.36
1.4
1.2
2.90
3.05
g/l
—
9
33
10
16
6.33
4.30
9.5
5.9
—
—
—
0
0
16
51
3.19
4.23
1.4
1.1
—
—
—
0
0
50
274
1.89
4.13
2.5
3.0
—
—
—
0
0
14
35
4.06
4.12
1.3
1.2
—
—
—
0
0
20
74
2.76
4.12
4.4
4.6
6.39
7.23
mmol/l
1.02
15
65
14
42
3.38
4.06
1.8
2.9
40.07
40.67
%
—
6
21
18
64
2.86
3.98
1.1
1.3
—
—
—
0
0
17
59
2.93
3.92
1.1
1.3
—
—
—
0
0
17
59
2.93
3.92
2.1
2.5
17.12
60.41
iu/ml
—
6
8
55
317
1.80
3.89
2.3
2.5
17.22
23.30
au/ml
—
5
28
15
388
0.37
3.78
1.1
1.4
—
—
—
0
0
83
542
1.61
3.73
2.5
2.4
180.64
154.08
ug/g
0.24
73
430
14
39
3.64
3.71
1.3
1.2
—
—
—
0
0
8
12
6.73
3.68
1.8
8.3
43.81
44.71
%
—
8
12
8
12
6.73
3.68
1.3
1.4
—
—
—
0
0
14
45
3.16
3.67
1.9
1.8
38.98
36.34
%
0.19
14
45
196
1535
1.39
3.57
1.4
1.4
—
—
—
0
0
17
63
2.74
3.51
4.4
3.8
10.90
11.07
index
—
10
46
45
253
1.83
3.47
1.4
1.2
—
—
—
0
0
590
5536
1.55
3.37
6.4
5.9
2.43
2.62
mmol/l
5.90
553
5063
18
71
2.58
3.32
1.4
1.8
9.10
10.37
%
0.59
18
71
64
404
1.65
3.30
3.3
2.6
5.96
6.07
ph
0.42
47
283
581
5441
1.51
3.27
5.6
5.2
4.27
4.50
mmol/l
6.04
549
5010
30
150
2.05
3.25
2.2
2.4
190.44
92.72
ug/min
0.29
16
89
47
274
1.77
3.23
2.4
1.3
171.65
207.71
u/ml
0.24
42
253
556
5168
1.45
3.20
4.7
4.3
1.36
1.28
mmol/l
1.89
514
4675
16
61
2.66
3.15
1.3
1.5
—
—
—
0
0
577
5408
1.48
3.11
5.4
5.1
1.34
1.42
mmol/l
4.47
537
4939
10
25
4.04
3.09
1.1
1.0
1864.30
1410.92
miu/ml
—
10
25
7
12
5.88
3.02
1.4
2.1
—
—
—
0
0
15
57
2.67
2.98
1.1
1.2
—
—
—
0
0
9
22
4.13
2.89
1.8
1.4
—
—
—
0
0
23
110
2.13
2.81
1.3
1.4
—
—
—
0
0
166
2057
0.74
2.78
3.2
3.3
—
—
—
0
0
13
48
2.74
2.73
1.8
2.3
858.00
693.64
ml
—
8
28
15
60
2.53
2.72
1.1
1.1
—
—
—
0
0
6
10
6.04
2.70
1.5
1.3
—
—
—
0
0
107
791
1.42
2.68
1.3
1.4
—
—
—
0
0
10
30
3.37
2.61
1.2
1.4
151.30
137.80
nmol/l
—
10
30
6
11
5.49
2.55
3.8
5.4
4.87
4.98
kpa
—
6
11
28
151
1.89
2.51
1.5
1.4
233.53
264.93
ug/g
0.36
15
95
7
16
4.41
2.48
1.0
1.0
—
—
—
0
0
7
16
4.41
2.48
1.0
1.2
—
—
—
0
0
14
57
2.49
2.46
1.1
1.2
—
—
—
0
0
12
45
2.70
2.46
2.2
3.5
8.32
8.08
mmol/l
0.09
12
45
6
12
5.03
2.40
1.0
1.1
—
—
—
0
0
12
46
2.64
2.37
2.3
3.7
14.11
16.74
%
2.19
12
46
7
17
4.15
2.36
1.1
1.4
—
—
—
0
0
5
155
0.32
2.30
1.0
1.2
1.38
1.52
g/l
—
5
155
295
2574
1.26
2.29
5.4
5.6
2.09
2.66
ug/l
1.17
266
2305
66
464
1.47
2.18
8.2
3.6
—
—
—
0
0
78
568
1.42
2.15
1.6
1.4
—
—
—
0
0
13
55
2.39
2.13
1.4
1.6
26.39
43.89
ng/l
0.38
13
55
5
10
5.03
2.07
1.0
1.1
—
—
—
0
0
5
10
5.03
2.07
1.4
2.6
—
—
—
0
0
6
163
0.36
2.03
1.0
1.3
0.84
0.90
g/l
—
6
163
21
113
1.89
1.93
1.3
1.4
392.65
242.11
miu/ml
—
5
49
13
58
2.27
1.92
1.0
1.3
—
—
nmol/l
—
0
0
6
18
3.35
1.75
3.2
2.1
13.02
17.17
u/l
—
6
18
8
30
2.69
1.73
1.1
2.8
1101.75
1661.73
u/ml
—
8
30
16
84
1.93
1.61
2.1
2.6
—
—
—
0
0
14
70
2.02
1.60
1.0
1.4
—
—
—
0
0
8
32
2.52
1.60
2.9
2.0
34.75
40.26
g/l
—
8
32
16
85
1.90
1.56
1.1
1.1
300.67
59.42
iu/ml
—
6
12
5
15
3.35
1.52
1.2
1.7
—
—
—
0
0
5
15
3.35
1.52
1.2
1.1
—
—
—
0
0
13
65
2.02
1.49
1.1
1.1
—
—
—
0
0
9
37
2.45
1.48
3.6
1.4
225.44
84.67
ng/l
—
9
37
81
636
1.31
1.44
1.6
1.3
—
—
—
0
0
5
16
3.14
1.44
2.0
3.7
—
—
—
0
0
0
41
0.00
1.31
0.0
1.1
—
10.44
—
0
11
5
18
2.79
1.28
2.0
1.5
4.40
4.17
%
—
5
18
5
18
2.79
1.28
2.2
1.5
30.80
37.44
%
—
5
18
13
70
1.87
1.24
1.1
1.3
—
—
—
0
0
6
25
2.41
1.24
1.2
1.1
10.83
17.44
umol/l
—
6
20
6
25
2.41
1.24
3.8
1.8
95.50
56.82
ug/l
—
6
25
24
155
1.57
1.24
7.2
4.6
—
—
—
0
0
5
19
2.64
1.22
1.4
2.3
—
—
—
0
0
10
50
2.02
1.17
1.7
1.3
—
—
—
0
0
0
33
0.00
1.16
0.0
1.5
—
1.32
—
0
18
0
33
0.00
1.16
0.0
1.5
—
—
—
0
0
0
35
0.00
1.15
0.0
1.6
—
—
—
0
0
37
269
1.40
1.11
2.8
2.6
—
—
—
0
0
7
31
2.27
1.10
1.1
1.3
—
—
—
0
0
5
21
2.39
1.09
1.0
1.0
—
26.60
—
0
5
6
121
0.49
1.06
1.7
1.7
—
—
—
0
0
5
23
2.18
0.98
1.0
1.3
21.00
8.09
mm/h
—
5
23
24
165
1.47
0.98
11.4
10.2
—
—
—
0
0
256
2345
1.15
0.97
2.0
1.9
1.39
1.35
mmol/l
0.36
221
1907
15
231
0.64
0.92
1.3
1.1
—
—
—
0
0
8
44
1.83
0.86
1.1
1.2
90.13
104.45
pmol/l
—
8
44
6
31
1.94
0.84
2.0
1.6
14.98
10.39
umol/l
—
6
21
5
24
2.09
0.74
1.0
1.0
238.60
185.29
mmol/24h
—
5
24
10
60
1.68
0.72
1.3
1.2
—
—
—
0
0
5
26
1.93
0.70
1.4
1.1
—
—
—
0
0
62
523
1.20
0.67
1.4
1.5
—
—
—
0
0
10
62
1.62
0.65
1.1
1.2
—
—
—
0
0
13
189
0.68
0.64
1.7
1.7
—
—
—
0
0
5
30
1.67
0.61
1.0
1.8
227.60
293.91
mu/l
—
5
22
22
165
1.34
0.61
1.8
1.8
45.09
40.97
nmol/l
0.46
22
156
12
173
0.69
0.58
1.2
1.2
—
—
—
0
0
9
62
1.46
0.53
1.1
1.2
—
—
—
0
0
10
66
1.52
0.52
1.4
3.2
4.39
3.21
nmol/l
—
10
66
62
538
1.17
0.52
2.4
2.3
12.32
13.32
nmol/l
0.38
54
487
11
75
1.47
0.51
1.1
1.1
6.20
4.11
u/ml
—
5
35
10
67
1.50
0.50
1.6
1.7
—
—
—
0
0
40
336
1.20
0.48
1.3
1.3
—
—
—
0
0
11
76
1.45
0.48
3.0
2.6
—
—
—
0
0
25
201
1.25
0.45
3.6
3.0
35.87
141.86
u/ml
0.99
25
192
5
31
1.62
0.43
1.0
1.0
—
—
—
0
0
5
31
1.62
0.43
2.4
2.5
—
—
—
0
0
5
34
1.47
0.40
1.0
3.9
192.00
122.15
nmol/l
—
5
34
12
159
0.75
0.38
1.1
1.1
—
—
—
0
0
5
36
1.39
0.38
7.2
2.4
30.20
38.68
mg/l
—
5
25
13
100
1.31
0.33
1.4
1.9
299.92
291.74
mu/l
0.06
13
92
5
38
1.32
0.23
2.0
1.7
—
—
—
0
0
56
517
1.09
0.22
1.5
1.5
—
—
—
0
0
5
42
1.19
0.21
1.2
1.4
51.82
27.81
u/l
—
5
32
6
48
1.25
0.20
1.8
1.8
—
—
—
0
0
6
52
1.16
0.19
1.0
1.4
—
—
—
0
0
6
52
1.16
0.19
2.0
2.2
—
—
—
0
0
161
1554
1.05
0.18
3.3
3.3
0.69
0.80
ug/l
1.11
116
1060
8
71
1.13
0.16
1.1
1.2
—
—
—
0
0
10
116
0.86
0.12
1.4
1.4
—
—
—
0
0
29
270
1.08
0.10
1.1
1.2
162.60
153.83
u/ml
0.03
13
100
5
48
1.04
0.09
1.8
2.5
—
—
—
0
0
8
77
1.04
0.07
1.8
1.1
—
—
—
0
0
8
77
1.04
0.07
1.8
1.1
—
—
—
0
0
15
138
1.09
0.06
1.9
1.8
218.20
218.35
pmol/l
0.00
15
129
36
356
1.01
0.00
1.3
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
8.8
—
0.35
—
0
6
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
4.2
—
12.00
—
0
6
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
3.5
—
5.53
—
0
6
0
5
0.00
-0.00
0.0
6.2
—
49.00
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
35.20
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
402.00
—
0
5
0
9
0.00
-0.00
0.0
4.8
—
7.84
—
0
9
0
5
0.00
-0.00
0.0
12.4
—
7.60
—
0
5

Mortality – FinRegistry

Association

Association between endpoint M13_DISCITIS and mortality.

Females

Parameter HR [95% CI] p-value
M13_DISCITIS 2.337 [1.84, 2.97] < 0.001
Birth year 0.997 [0.99, 1.01] 0.524

During the follow-up period (1.1.1998 — 31.12.2019), 358 out of 1285 females with M13_DISCITIS died.

Males

Parameter HR [95% CI] p-value
M13_DISCITIS 2.407 [1.94, 2.98] < 0.001
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 569 out of 1892 males with M13_DISCITIS died.

Mortality risk

Mortality risk for people of age

years, who have M13_DISCITIS.

N-year risk Females Males
1 0.203% 0.437%
5 1.306% 2.524%
10 3.654% 6.535%
15 7.338% 12.408%
20 12.465% 20.51%

Relationships between endpoints

Index endpoint: M13_DISCITIS – Discitis, unspecified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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