No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
423 |
4. Check minimum number of eventsNone |
423 |
5. Include endpointsNone |
423 |
6. Filter based on genotype QC (FinnGen only) |
380 |
Control definitions (FinnGen only)
- Control exclude
- K11_OESSTODUO
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- K20-K31
- Name in latin
- Ulcus pepticum loco non specificato
Similar endpoints
↥List of similar endpoints to
Peptic ulcer
based on the number of shared cases.
Similar with more cases:
- Gastroduodenal ulcer
- Diseases of oesophagus, stomach and duodenum
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4182 | 1927 | 2191 |
| Only index persons | 3048 | 1448 | 1600 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.06 | 0.06 |
| Only index persons | 0.06 | 0.05 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 63.74 | 68.52 | 59.49 |
| Only index persons | 61.57 | 66.17 | 57.40 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 380 | 181 | 199 |
| Unadjusted period prevalence (%) | 0.08 | 0.06 | 0.09 |
| Median age at first event (years) | 60.29 | 56.74 | 63.51 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 393
- Matched controls
- 3929
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
16.0
178.6
254
403
K27.9
ICD-10 Finland
Peptic ulcer, site unspecified, unspecified as acute or chronic, without haemorrhage or perforation
+∞
149.8
134
*
K27.0
ICD-10 Finland
Peptic ulcer, site unspecified, acute with haemorrhage
+∞
114.3
104
*
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
24.9
74.0
54
25
UJD02
NOMESCO Finland
Gastroscopy
15.4
53.7
49
36
K92.1
ICD-10 Finland
Melaena
9.4
50.6
66
83
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
12.3
41.3
43
39
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.7
36.6
198
840
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
+∞
33.8
32
*
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
6.8
30.5
51
84
K27.1
ICD-10 Finland
Peptic ulcer, site unspecified, acute with perforation
+∞
29.5
28
*
K27.4
ICD-10 Finland
Peptic ulcer, site unspecified, chronic or unspecified with haemorrhage
+∞
28.5
27
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.6
27.1
72
181
K27.3
ICD-10 Finland
Peptic ulcer, site unspecified, acute without haemorrhage or perforation
+∞
25.3
24
*
K25.4
ICD-10 Finland
Gastric ulcer, Chronic or unspecified with haemorrhage
+∞
24.2
23
*
K25.0
ICD-10 Finland
Gastric ulcer, Acute with haemorrhage
+∞
24.2
23
*
A02BC01
ATC
omeprazole; systemic
3.0
22.3
144
642
A02BC03
ATC
lansoprazole; oral
2.9
22.1
145
651
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
7.7
21.5
31
43
53399
ICD-8 Finland
Peptic ulcer, site unspecified, Without mention of perforation
+∞
21.0
20
*
D64.9
ICD-10 Finland
Anaemia, unspecified
3.6
20.5
77
247
R10.1
ICD-10 Finland
Pain localized to upper abdomen
3.2
19.5
95
358
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
7.0
19.0
30
46
A02BC02
ATC
pantoprazole; systemic
2.8
18.6
292
1981
K29.3
ICD-10 Finland
Chronic superficial gastritis
55.3
18.1
21
*
K29.7
ICD-10 Finland
Gastritis, unspecified
25.4
17.5
24
10
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.3
17.2
77
274
K30
ICD-10 Finland
Functional dyspepsia
4.5
17.2
44
106
JN3AD
NOMESCO Finland
Abdominal CT examination
3.2
16.7
76
273
K25.3
ICD-10 Finland
Gastric ulcer, Acute without haemorrhage or perforation
177.2
16.6
17
*
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.0
16.5
51
142
UJF32
NOMESCO Finland
Coloscopy
2.6
16.3
125
595
K27.7
ICD-10 Finland
Peptic ulcer, site unspecified, chronic without haemorrhage or perforation
+∞
13.6
13
*
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
35.4
13.6
17
5
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.7
13.1
86
375
E66.8
ICD-10 Finland
Other obesity
5.0
12.8
28
59
A02BA02
ATC
ranitidine; systemic
2.5
12.8
94
433
K92.0
ICD-10 Finland
Haematemesis
11.6
12.7
23
21
K27.5
ICD-10 Finland
Peptic ulcer, site unspecified, chronic or unspecified with perforation
+∞
12.6
12
*
K26.0
ICD-10 Finland
Duodenal ulcer, acute with haemorrhage
+∞
12.6
12
*
K25.1
ICD-10 Finland
Gastric ulcer, Acute with perforation
+∞
12.6
12
*
JDA60
NOMESCO Finland
Closure of perforated ulcer of stomach
+∞
12.6
12
*
A02BD03
ATC
lansoprazole, amoxicillin and metronidazole; systemic
4.0
12.4
37
100
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.6
12.4
30
69
R10.0
ICD-10 Finland
Acute abdomen
5.9
12.1
22
39
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
19.7
11.7
17
9
K26.9
ICD-10 Finland
Duodenal ulcer, unspecified as acute or chronic, without haemorrhage or perforation
+∞
11.5
11
*
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
+∞
11.5
11
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
11.4
104
525
C03CA01
ATC
furosemide; systemic
2.1
11.2
163
991
N02AX02
ATC
tramadol; systemic, rectal
2.1
11.0
185
1185
R11
ICD-10 Finland
Nausea and vomiting
3.1
11.0
50
178
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
10.5
136
788
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
19.4
10.3
15
8
A02BC05
ATC
esomeprazole; systemic
2.0
10.3
153
933
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.8
9.8
54
214
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.8
9.4
29
80
R50.9
ICD-10 Finland
Fever, unspecified
2.4
9.4
73
341
K26.3
ICD-10 Finland
Duodenal ulcer, acute without haemorrhage or perforation
+∞
9.4
9
*
K26.4
ICD-10 Finland
Duodenal ulcer, chronic or unspecified with haemorrhage
+∞
9.4
9
*
53390
ICD-8 Finland
Peptic ulcer, site unspecified, Perforatione non indicata, cum haemorrhagia
+∞
9.4
9
*
JAH00
NOMESCO Finland
Laparotomy
4.8
9.2
21
46
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
3.4
9.1
34
107
N05BA01
ATC
diazepam; systemic, rectal
2.5
9.0
62
274
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.0
9.0
117
674
JKA20
NOMESCO Finland
Cholecystectomy
4.8
8.9
20
43
P01AB01
ATC
metronidazole; oral, rectal
1.9
8.9
158
1014
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.0
8.9
42
153
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.2
8.8
86
444
A06AD11
ATC
lactulose; oral
2.3
8.7
79
394
J01FF01
ATC
clindamycin; systemic
2.0
8.6
111
635
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
20.6
8.5
12
6
K29.9
ICD-10 Finland
Gastroduodenitis, unspecified
91.9
8.4
9
*
J01MA12
ATC
levofloxacin; systemic
2.2
8.4
86
450
K27.2
ICD-10 Finland
Peptic ulcer, site unspecified, acute with both haemorrhage and perforation
+∞
8.4
8
*
N03AX16
ATC
[U] pregabalin
2.1
8.2
96
530
A03FA02
ATC
cisapride; oral, rectal
2.9
8.1
38
138
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.5
8.0
52
223
E86
ICD-10 Finland
Volume depletion
6.3
7.9
20
33
ZXD05
NOMESCO Finland
Urgent procedure
1.9
7.9
123
750
J01MA02
ATC
ciprofloxacin; systemic
1.8
7.6
162
1090
SPAT1262
SPAT
Handing over of treatment supplies
2.1
7.5
76
395
JDA32
NOMESCO Finland
Endoscopic injection in stomach or pylorus
81.6
7.4
8
*
EBA15
NOMESCO Finland
Extraction of multiple teeth
4.0
7.3
21
55
C10AC01
ATC
colestyramine; oral
6.4
7.3
18
29
K29.0
ICD-10 Finland
Acute haemorrhagic gastritis
+∞
7.3
7
*
JDA61
NOMESCO Finland
Laparoscopic closure of perforated ulcer of stomach
+∞
7.3
7
*
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.1
7.3
81
437
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.3
7.1
57
269
N05CF01
ATC
zopiclone; oral
1.8
7.0
141
925
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
7.0
115
709
UJF92
NOMESCO Finland
Capsular endoscopy
7.7
7.0
15
20
R52.2
ICD-10 Finland
Other chronic pain
3.8
6.8
21
58
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
11.2
6.8
12
11
D06
ICPC
Abdominal pain localized other
2.7
6.8
36
139
R07.3
ICD-10 Finland
Other chest pain
2.5
6.8
46
201
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.2
6.8
58
281
L04AX01
ATC
azathioprine; systemic
4.0
6.8
19
49
K29.4
ICD-10 Finland
Chronic atrophic gastritis
23.0
6.7
9
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.3
6.6
17
41
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
3.9
6.6
19
50
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.0
6.6
74
400
A07AA09
ATC
vancomycin; oral
10.3
6.6
12
12
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.3
6.5
24
75
E66.01
ICD-10 Finland
Obesity due to excess calories
2.6
6.5
38
155
K27
ICD-10 Finland
Peptic ulcer, site unspecified
70.9
6.4
7
*
K22.6
ICD-10 Finland
Gastro-oesophageal laceration-haemorrhage syndrome
70.9
6.4
7
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.6
6.4
21
61
K65.0
ICD-10 Finland
Acute peritonitis
9.5
6.3
12
13
A02BA04
ATC
nizatidine; systemic
2.6
6.3
36
145
J02AC01
ATC
fluconazole; systemic
1.8
6.3
128
839
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
+∞
6.3
6
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
6.3
81
460
K86.3
ICD-10 Finland
Pseudocyst of pancreas
27.1
6.2
8
*
I85.0
ICD-10 Finland
Oesophageal varices with bleeding
27.1
6.2
8
*
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
3.5
6.2
21
62
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.2
6.2
53
257
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.2
6.1
24
78
T36
ICD-10 Finland
Poisoning by systemic antibiotics
4.2
6.1
16
39
I50.9
ICD-10 Finland
Heart failure, unspecified
2.0
6.1
78
440
Z3229
NOMESCO Finland
Other healthcare associate professional
2.4
6.1
42
185
ZX120
NOMESCO Finland
Intravenous
2.3
6.1
45
205
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.2
6.0
51
246
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
6.0
187
1374
D01
ICPC
Abdominal pain/cramps general
2.3
6.0
48
226
C07AB07
ATC
bisoprolol; oral
1.7
6.0
202
1516
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
193
976
2.92
24.00
4.0
2.4
52.04
61.49
u/l
1.21
180
897
63
223
3.17
14.09
1.9
1.5
—
—
—
0
0
150
831
2.30
13.58
3.9
2.1
3.22
3.10
mg/l
0.23
140
705
248
1687
2.27
13.57
9.9
6.5
12.39
11.66
umol/l
0.29
236
1610
110
539
2.44
13.12
3.5
2.5
11.25
12.76
umol/l
1.22
103
500
103
502
2.42
12.35
3.6
2.5
2.37
2.25
g/l
1.09
96
467
95
471
2.34
10.83
3.6
2.6
20.16
22.53
%
0.71
90
440
109
575
2.24
10.72
1.9
1.7
1200.84
1216.10
nmol/l
0.05
87
422
209
1451
1.94
9.42
4.3
2.8
—
—
estimate
—
0
0
73
344
2.38
9.24
3.2
2.9
9.31
7.73
umol/l
0.30
65
311
188
1281
1.90
8.77
5.2
3.9
37.29
138.01
ng/l
0.90
146
967
176
1185
1.88
8.42
4.3
3.3
—
—
—
0
0
167
1106
1.89
8.41
4.1
3.4
257.48
76.89
e6/l
0.37
139
860
203
1433
1.86
8.34
8.4
4.6
33.34
35.36
g/l
4.84
197
1339
221
1605
1.86
8.26
21.1
15.2
1.27
1.28
inr
0.14
194
1335
127
778
1.93
8.05
3.5
2.7
5.17
5.05
e6/l
0.05
120
711
101
575
2.02
7.88
2.4
1.8
—
—
—
0
0
92
511
2.04
7.67
2.1
1.9
31.75
29.04
s
1.96
92
498
22
58
3.96
7.63
1.3
1.5
—
—
—
0
0
59
280
2.30
7.29
9.8
7.2
11.58
10.43
mmol/l
0.56
59
265
148
978
1.82
7.27
2.4
2.1
240.72
239.18
u/l
0.01
141
932
29
97
3.15
7.08
1.3
1.2
—
—
—
0
0
142
946
1.78
6.67
4.0
3.2
0.50
0.42
e6/l
0.22
113
705
77
423
2.02
6.55
2.4
1.7
—
—
—
0
0
63
324
2.12
6.38
6.3
3.5
1.38
1.97
mmol/l
0.58
53
274
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
27
93
3.04
6.29
2.6
2.2
0.28
0.35
iu/ml
0.40
17
43
22
67
3.42
6.23
1.4
1.5
—
—
—
0
0
290
2395
1.80
6.12
13.3
7.9
93.08
79.21
u/l
2.62
281
2253
229
1773
1.70
6.08
12.1
9.5
4.65
4.15
e9/l
1.95
213
1556
242
1904
1.70
6.03
7.2
4.7
7.19
6.72
mmol/l
2.09
236
1817
257
2063
1.71
5.87
7.1
4.7
62.20
2662.07
e6/l
—
10
41
41
183
2.38
5.81
4.0
3.9
1.06
2.19
mmol/l
0.89
30
133
69
380
1.99
5.80
8.0
6.6
0.35
1.05
mmol/l
0.68
58
316
56
288
2.10
5.66
3.9
2.4
24.96
30.09
u/l
1.84
51
230
72
407
1.94
5.61
2.5
1.8
—
—
—
0
0
22
72
3.18
5.58
1.4
1.3
259.60
266.85
ug/g
0.05
13
36
186
1388
1.64
5.50
5.6
2.9
137.36
138.68
ug/l
0.03
179
1284
63
343
2.00
5.46
6.2
3.4
5.81
5.78
kpa
0.08
63
329
114
750
1.73
5.42
4.0
2.4
—
—
—
0
0
101
645
1.76
5.32
1.5
1.2
5.41
1.54
u/ml
0.73
38
173
56
299
2.02
5.11
5.1
2.7
4.42
4.34
kpa
0.15
56
285
23
82
2.92
5.07
1.3
1.6
—
—
—
0
0
22
79
2.89
4.79
1.4
1.5
—
—
—
0
0
24
93
2.68
4.56
2.0
1.6
—
—
—
0
0
46
239
2.05
4.53
3.5
3.0
265.28
232.54
ng/l
0.13
40
220
17
56
3.13
4.29
1.4
1.5
—
—
—
0
0
15
46
3.35
4.23
1.3
1.5
—
—
—
0
0
151
1124
1.56
4.22
4.3
3.3
7.24
7.48
mmol/l
0.28
129
938
19
68
2.88
4.18
1.7
1.5
—
—
—
0
0
99
668
1.64
4.17
2.3
1.6
2.17
1.39
mg/l
0.53
85
529
36
176
2.15
4.15
1.8
1.4
—
—
—
0
0
191
1502
1.53
4.13
10.2
6.0
1.20
1.21
mmol/l
1.06
185
1362
238
1977
1.52
3.87
4.7
3.1
80.28
50.27
u/l
2.41
225
1861
146
1095
1.53
3.87
4.6
4.1
6.60
11.18
mg/mmol
0.76
104
662
182
1431
1.51
3.86
2.9
2.1
87.48
95.22
pmol/l
1.61
120
721
206
1662
1.50
3.85
10.9
6.6
1.21
1.21
mmol/l
0.55
184
1419
15
49
3.14
3.84
1.3
1.3
—
—
—
0
0
133
979
1.54
3.84
2.2
1.7
20.80
20.51
nmol/l
0.08
121
811
37
189
2.06
3.82
7.5
3.6
52.71
46.07
%
0.92
37
183
32
156
2.14
3.73
6.1
3.2
24.44
25.25
mmol/l
0.69
32
150
141
1058
1.52
3.70
3.4
3.3
1955.97
1578.35
ng/l
0.39
124
909
22
92
2.47
3.63
1.5
1.6
—
—
—
0
0
85
572
1.62
3.58
3.4
3.0
1.03
1.01
e6/l
0.02
48
319
99
695
1.57
3.49
2.0
1.8
90123840.56
20454995.26
pmol/l
0.34
81
572
21
89
2.44
3.38
1.5
1.3
—
—
—
0
0
16
59
2.78
3.36
1.0
1.3
—
—
—
0
0
20
83
2.48
3.36
4.8
3.5
1.50
2.00
index
0.19
12
48
24
110
2.26
3.26
2.0
2.5
—
—
—
0
0
92
646
1.55
3.22
5.0
3.7
119.56
276.89
ng/l
1.06
72
521
15
56
2.74
3.09
1.3
1.3
—
—
—
0
0
15
56
2.74
3.09
1.3
1.3
—
—
—
0
0
8
16
5.08
3.06
1.0
1.3
—
—
—
0
0
125
946
1.47
3.05
5.5
4.0
0.00
0.01
estimate
0.50
47
325
13
45
2.95
3.05
1.3
1.3
—
162.07
—
0
15
10
27
3.77
2.90
1.9
2.6
—
—
—
0
0
15
59
2.60
2.82
1.2
1.6
—
—
—
0
0
197
1643
1.40
2.75
5.7
3.9
0.00
0.00
estimate
-0.00
51
353
11
34
3.30
2.74
1.3
1.9
—
—
—
0
0
12
41
2.99
2.64
1.8
1.3
—
—
—
0
0
198
1663
1.38
2.60
5.8
3.9
0.00
0.01
estimate
0.50
53
366
74
519
1.52
2.58
3.4
3.1
1.14
1.52
e6/l
0.40
37
266
11
36
3.11
2.58
1.3
1.8
—
—
—
0
0
15
62
2.48
2.57
2.8
1.7
4415.60
8776.48
u/l
—
5
13
13
50
2.65
2.55
1.3
1.2
—
—
—
0
0
10
31
3.28
2.53
1.5
1.4
—
—
—
0
0
7
16
4.43
2.48
3.3
1.7
100.31
84.80
ng/l
—
7
16
41
252
1.70
2.45
5.7
3.8
88.77
88.02
ng/l
0.02
35
214
11
38
2.95
2.43
1.4
1.4
—
—
—
0
0
11
38
2.95
2.43
1.4
1.4
—
—
—
0
0
52
341
1.60
2.43
3.6
4.4
3.34
20.75
ug/l
0.79
46
283
12
46
2.66
2.38
1.1
1.4
—
—
—
0
0
8
22
3.69
2.37
1.5
1.5
—
—
—
0
0
155
1265
1.37
2.37
6.0
3.9
0.07
0.04
estimate
0.24
42
301
11
39
2.87
2.36
1.4
1.4
—
—
—
0
0
45
287
1.64
2.35
3.8
2.6
1.00
0.60
e6/l
0.32
45
272
197
1676
1.35
2.29
5.8
3.9
0.06
0.89
estimate
0.45
48
337
11
41
2.73
2.22
1.4
1.4
—
—
—
0
0
11
41
2.73
2.22
1.4
1.4
—
—
—
0
0
11
42
2.66
2.16
1.3
1.4
—
—
—
0
0
22
116
1.95
2.15
1.7
1.6
0.54
0.29
mg/l
0.76
15
48
12
49
2.49
2.12
1.3
1.1
573.80
277.03
u/ml
—
5
31
104
809
1.39
2.10
3.5
2.9
346.94
352.12
umol/l
0.17
88
713
27
155
1.80
2.06
1.3
1.1
182.07
163.40
u/ml
0.06
11
57
17
83
2.10
2.04
1.6
2.7
28.38
90.87
ug/min
—
10
50
5
11
4.59
1.94
1.0
2.9
113.20
91.73
%
—
5
11
9
33
2.77
1.94
1.6
1.2
—
—
—
0
0
6
16
3.79
1.94
1.0
1.3
—
—
—
0
0
136
1124
1.32
1.83
4.1
3.4
2.34
2.36
mmol/l
1.05
117
1021
257
2320
1.31
1.77
5.7
4.1
16.32
12.66
mm/h
2.52
243
2127
94
741
1.35
1.73
6.3
4.2
1.02
1.02
kg/l
0.56
72
477
8
30
2.70
1.73
1.5
1.6
—
—
—
0
0
8
30
2.70
1.73
1.5
1.6
—
—
—
0
0
8
30
2.70
1.73
1.5
1.6
—
—
—
0
0
10
40
2.54
1.67
1.4
1.4
—
—
—
0
0
5
14
3.60
1.62
1.4
2.6
—
—
—
0
0
8
32
2.53
1.60
1.0
1.3
—
—
—
0
0
110
898
1.31
1.59
5.2
3.4
0.05
0.11
estimate
0.26
41
283
49
352
1.45
1.55
4.5
3.5
—
—
—
0
0
32
212
1.55
1.48
2.6
1.7
—
—
—
0
0
10
45
2.25
1.47
1.3
1.1
—
—
—
0
0
5
16
3.15
1.44
1.0
1.1
—
—
—
0
0
6
22
2.75
1.44
1.0
1.1
—
—
—
0
0
22
134
1.68
1.42
1.0
1.0
—
—
—
0
0
16
89
1.83
1.39
1.9
1.3
—
—
—
0
0
6
24
2.52
1.31
1.2
1.5
—
—
—
0
0
5
18
2.80
1.29
1.4
1.4
—
—
—
0
0
5
19
2.65
1.22
1.2
1.6
66.40
84.84
umol/l
—
5
19
5
19
2.65
1.22
1.4
1.5
—
—
—
0
0
5
20
2.52
1.15
1.0
1.1
—
—
—
0
0
18
111
1.65
1.14
4.6
3.0
1.73
2.54
ratio
—
9
64
7
31
2.28
1.11
1.9
1.3
28.34
20.93
u/l
—
7
24
10
52
1.95
1.07
4.4
3.1
10.44
8.39
pmol/l
—
10
52
42
317
1.36
1.05
2.4
2.0
1.63
1.47
%
0.61
34
274
14
83
1.71
1.02
1.2
1.2
—
—
—
0
0
14
83
1.71
1.02
1.2
1.2
—
—
—
0
0
7
35
2.02
1.00
1.3
1.1
—
—
—
0
0
7
36
1.96
0.97
5.6
4.8
—
—
—
0
0
283
2976
0.82
0.94
5.9
5.0
1.38
1.45
mmol/l
2.07
269
2719
291
3052
0.82
0.94
6.6
5.9
2.45
2.64
mmol/l
3.05
279
2800
285
2993
0.83
0.92
6.0
5.1
4.37
4.55
mmol/l
2.20
272
2749
14
86
1.65
0.92
2.2
1.6
—
—
—
0
0
28
377
0.72
0.88
6.0
4.8
30.09
31.84
%
0.32
23
229
81
688
1.22
0.84
4.0
2.9
2.45
2.46
mmol/l
0.23
70
632
6
32
1.89
0.82
1.3
1.2
—
—
—
0
0
15
98
1.55
0.79
6.9
2.6
1.73
1.63
mmol/l
0.30
15
93
11
66
1.69
0.79
1.2
1.2
—
13.10
—
0
8
153
1387
1.17
0.77
3.6
2.3
72.14
78.32
nmol/l
1.85
143
1238
7
38
1.86
0.74
1.3
1.1
—
—
—
0
0
18
127
1.44
0.69
1.8
1.8
—
—
—
0
0
19
136
1.42
0.68
1.4
1.4
—
—
—
0
0
10
62
1.63
0.65
2.1
1.4
—
—
—
0
0
10
62
1.63
0.65
1.7
1.4
—
—
—
0
0
7
44
1.60
0.65
2.9
1.4
11.71
9.77
mmol/l
—
7
44
82
932
0.85
0.65
4.9
4.6
19.45
22.04
%
1.11
41
471
55
468
1.20
0.59
1.5
1.5
—
—
—
0
0
283
2935
0.87
0.57
29.9
16.2
79.54
78.20
ml/min/173m2
0.44
272
2726
186
1740
1.13
0.57
3.4
2.7
—
—
—
0
0
59
509
1.19
0.55
1.3
1.3
1.49
13.56
u/ml
3.75
25
210
31
250
1.26
0.54
5.8
2.6
65.46
62.02
ml/min/173m2
0.14
13
103
314
3045
1.15
0.52
34.0
15.9
28.94
25.69
mg/l
0.98
283
2509
10
67
1.51
0.50
1.9
1.2
—
—
—
0
0
107
1164
0.89
0.46
6.5
5.4
2.85
3.65
ug/l
0.39
97
1036
62
698
0.87
0.45
3.1
3.1
0.68
0.82
ug/l
1.03
47
445
11
78
1.42
0.43
2.2
1.7
216.00
309.01
mu/l
1.22
11
73
5
31
1.62
0.43
2.2
1.8
—
—
—
0
0
16
122
1.32
0.43
1.8
1.6
—
—
—
0
0
8
56
1.44
0.43
2.0
1.9
—
—
—
0
0
5
32
1.57
0.42
1.2
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
5.9
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
63
564
1.14
0.39
1.3
1.3
46.56
33.70
iu/ml
0.26
16
182
11
80
1.39
0.38
1.4
1.2
—
—
—
0
0
277
2847
0.91
0.36
5.1
4.3
1.37
1.26
mmol/l
1.65
266
2582
121
1288
0.91
0.34
2.2
1.9
1.47
1.32
mmol/l
1.03
103
1061
6
86
0.69
0.33
1.7
1.9
—
—
—
0
0
240
2321
1.09
0.32
4.9
4.1
14.96
14.95
pmol/l
0.02
221
2105
288
2949
0.91
0.32
5.9
5.1
6.34
6.01
mmol/l
2.32
269
2667
7
54
1.30
0.30
1.0
1.2
21.00
20.08
u/l
—
7
42
21
178
1.19
0.26
1.2
1.4
—
50.48
—
0
17
9
77
1.17
0.24
1.1
1.2
—
—
—
0
0
315
3200
0.92
0.24
18.8
11.8
25.95
25.46
u/l
0.20
309
3096
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
9.88
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
15
127
1.19
0.20
1.6
1.6
20.68
5.63
iu/ml
—
6
30
6
80
0.75
0.15
1.7
1.2
—
—
—
0
0
27
248
1.09
0.13
1.3
1.5
—
—
—
0
0
5
65
0.77
0.08
1.2
1.2
—
58.57
—
0
10
12
133
0.90
0.08
2.0
2.4
—
—
—
0
0
40
384
1.05
0.06
12.0
7.5
—
—
—
0
0
39
375
1.04
0.06
1.5
1.5
—
—
—
0
0
21
198
1.06
0.05
2.6
2.6
—
11.68
—
0
15
12
111
1.08
0.04
1.7
2.4
—
—
—
0
0
24
246
0.97
0.00
1.7
2.2
—
—
—
0
0
290
2898
1.00
0.00
8.3
6.6
41.50
39.65
mmol/mol
1.94
277
2693
280
2801
1.00
0.00
6.1
5.1
1.84
1.96
mu/l
0.93
264
2553
26
263
0.99
0.00
1.6
2.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
21.16
—
0
9
8
80
1.00
-0.00
1.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_PULC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_PULC | 1.855 [1.57, 2.19] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.207 |
During the follow-up period (1.1.1998 — 31.12.2019), 586 out of 1363 females with K11_PULC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_PULC | 2.396 [1.99, 2.88] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 608 out of 1406 males with K11_PULC died.
Mortality risk
Mortality risk for people of age
years, who have K11_PULC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.215% | 0.419% |
| 5 | 1.024% | 2.613% |
| 10 | 2.649% | 6.388% |
| 15 | 4.898% | 11.583% |
| 20 | 8.644% | 19.041% |
Relationships between endpoints
↥Index endpoint: K11_PULC – Peptic ulcer
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data