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This is a non-core endpoint: only basic statistics are computed.

Frostbite involving multiple body regions and unspecified frostbite

ST19_FROST_INVOLVI_MULTIPLE_BODY_REGIONS_UNSPE_FROST

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 T35
  • Cause of death: ICD-10 T35

2 out of 7 registries used, show all original rules.

88

4. Check minimum number of events

None

88

5. Include endpoints

None

88

6. Filter based on genotype QC (FinnGen only)

83

Control definitions (FinnGen only)

Control exclude
ST19_FROSTBITE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
T3[3-5]
Name in latin
Congelatio multarum regionum corporis sive non specificata

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 83 24 59
Unadjusted period prevalence (%) 0.02 0.01 0.03
Median age at first event (years) 54.85 60.36 52.61

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
84
Matched controls
840
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
X31
ICD-10 Finland
Exposure to excessive natural cold
+∞
43.6
38
*
T35.5
ICD-10 Finland
Unspecified frostbite of lower limb
+∞
36.1
32
*
T35.4
ICD-10 Finland
Unspecified frostbite of upper limb
+∞
30.0
27
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
9.0
17.3
26
40
T68
ICD-10 Finland
Hypothermia
105.2
16.2
17
*
T35.0
ICD-10 Finland
Superficial frostbite involving multiple body regions
+∞
12.8
12
*
X59
ICD-10 Finland
Exposure to unspecified factor
4.5
10.2
35
114
AA1AD
NOMESCO Finland
CT of head and brain
4.3
9.9
42
159
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.3
8.7
29
91
SPAT1148
SPAT
Treatment of chronic ulcer or burn
4.7
8.3
23
62
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
9.9
7.7
15
18
NDQ20
NOMESCO Finland
Amputation of finger
87.5
7.5
8
*
G72.8
ICD-10 Finland
Other specified myopathies
17.8
7.5
11
7
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
+∞
7.4
7
*
T33.5
ICD-10 Finland
Superficial frostbite of wrist and hand
+∞
7.4
7
*
X58
ICD-10 Finland
Exposure to other specified factors
4.1
7.3
25
79
N07BB01
ATC
disulfiram; oral
8.0
7.2
16
24
W19
ICD-10 Finland
Unspecified fall
5.1
7.1
17
40
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.4
6.9
40
178
ZZA00
NOMESCO Finland
Split skin graft
19.9
6.4
9
5
T35.7
ICD-10 Finland
Unspecified frostbite of unspecified site
+∞
6.3
6
*
T34.5
ICD-10 Finland
Frostbite with tissue necrosis of wrist and hand
+∞
6.3
6
*
T35.3
ICD-10 Finland
Unspecified frostbite of thorax, abdomen, lower back and pelvis
+∞
6.3
6
*
P15
ICPC
Chronic alcohol abuse
7.9
6.0
13
19

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
47
219
3.60
7.77
4.5
2.4
1052.66
265.89
u/l
0.61
47
209
24
83
3.65
6.07
8.4
16.5
7.39
7.43
ph
0.98
15
48
24
84
3.60
5.96
2.7
1.5
—
—
—
0
0
26
113
2.88
4.42
2.1
2.0
30.48
29.08
s
0.46
26
113
15
49
3.51
4.04
7.1
9.2
24.80
24.39
mmol/l
0.17
15
49
52
330
2.51
4.01
11.2
12.8
1.18
1.23
inr
0.34
47
278
37
207
2.41
3.70
5.9
4.2
—
—
—
0
0
16
61
3.00
3.36
10.1
10.0
—
—
—
0
0
8
15
5.77
3.28
2.9
2.9
—
—
—
0
0
13
41
3.56
3.23
11.5
13.0
24.17
24.42
mmol/l
0.12
13
41
46
295
2.24
3.23
9.3
8.6
1.19
1.21
mmol/l
1.07
46
275
17
69
2.84
3.20
3.1
3.6
7.39
7.40
ph
0.43
11
46
13
45
3.23
3.19
4.1
1.5
0.59
0.29
mg/l
—
7
17
31
170
2.31
3.16
4.2
3.1
—
—
—
0
0
21
99
2.49
2.96
10.2
8.8
104.14
103.72
mmol/l
0.11
21
99
48
324
2.12
2.85
3.1
2.9
—
—
estimate
—
0
0
41
264
2.08
2.73
5.1
4.0
878.21
34.99
ng/l
0.48
34
187
12
44
3.02
2.67
4.2
16.3
—
—
—
0
0
13
51
2.83
2.59
3.6
3.5
—
—
—
0
0
6
13
4.88
2.31
1.8
2.6
55.90
64.14
%
—
6
13
6
14
4.53
2.19
1.0
4.2
48.38
65.99
%
—
6
14
33
210
1.94
2.17
5.7
4.3
7.40
7.40
ph
0.07
27
159
9
32
3.02
2.07
3.9
1.5
—
—
—
0
0
40
275
1.87
2.06
5.5
3.5
0.00
0.00
estimate
-0.00
11
65
10
39
2.77
2.02
1.2
2.2
24.80
24.52
mmol/l
—
10
39
9
34
2.84
1.93
3.9
1.5
—
—
—
0
0
7
22
3.37
1.92
3.1
3.3
7.41
7.40
ph
—
7
22
8
28
3.05
1.92
6.5
1.5
—
—
—
0
0
53
404
1.85
1.91
11.3
11.9
4.99
4.06
e9/l
1.02
45
356
9
35
2.76
1.86
3.9
1.5
—
—
—
0
0
9
35
2.76
1.86
3.9
1.5
—
—
—
0
0
9
35
2.76
1.86
3.9
1.5
—
—
—
0
0
9
36
2.68
1.80
2.7
2.7
1.49
1.41
%
—
9
36
8
30
2.84
1.77
7.0
5.0
36.63
37.00
°c
—
8
30
30
197
1.81
1.73
6.4
3.5
0.00
0.00
estimate
-0.00
13
70
43
317
1.73
1.66
17.7
12.7
0.00
0.00
e9/l
0.50
34
257
31
209
1.77
1.63
3.8
6.7
—
—
—
0
0
7
27
2.73
1.55
3.4
1.4
—
—
—
0
0
9
37
2.60
1.53
2.7
2.6
0.53
0.66
%
—
9
37
34
240
1.70
1.50
4.5
6.2
—
—
—
0
0
35
250
1.69
1.48
3.4
2.7
90.58
309.16
e6/l
0.38
30
190
47
365
1.65
1.43
5.3
3.4
0.00
0.00
estimate
-0.00
14
74
17
99
1.90
1.40
3.7
2.3
—
—
—
0
0
48
377
1.64
1.38
5.3
3.4
0.21
0.00
estimate
0.47
14
70
5
17
3.06
1.38
4.0
2.3
8.94
8.61
kpa
—
5
17
5
17
3.06
1.38
4.0
2.3
4.82
5.26
kpa
—
5
17
5
17
3.06
1.38
2.2
1.6
—
—
—
0
0
13
69
2.05
1.37
1.4
1.7
—
—
—
0
0
47
371
1.61
1.30
5.1
7.4
0.17
0.19
e9/l
0.53
41
331
47
373
1.59
1.25
5.4
3.4
0.00
21.65
estimate
0.49
13
75
19
120
1.75
1.22
1.9
2.7
2.44
2.46
mmol/l
0.30
12
99
37
280
1.57
1.19
3.6
3.3
705.38
23.97
e6/l
0.73
29
191
0
35
0.00
1.18
0.0
1.5
—
—
—
0
0
38
290
1.57
1.18
4.3
3.3
6.16
6.26
ph
0.21
25
156
30
217
1.59
1.16
2.9
2.4
—
—
—
0
0
45
358
1.55
1.16
5.1
7.2
0.04
0.04
e9/l
0.11
37
314
45
358
1.55
1.16
5.1
7.2
0.64
0.58
e9/l
0.73
36
314
46
368
1.55
1.15
5.1
7.2
1.74
1.99
e9/l
0.47
40
331
28
205
1.55
1.02
4.7
2.8
0.00
0.00
estimate
—
10
59
17
110
1.68
1.00
1.7
2.5
22.65
24.83
%
0.16
17
103
21
290
0.63
1.00
3.0
3.0
—
—
—
0
0
5
101
0.46
0.97
1.0
2.5
278.00
75.91
ug/g
—
5
83
18
254
0.63
0.93
1.9
2.0
—
—
—
0
0
0
26
0.00
0.80
0.0
1.3
—
0.25
—
0
26
0
26
0.00
0.80
0.0
1.4
—
1.22
—
0
26
0
26
0.00
0.80
0.0
1.6
—
—
—
0
0
10
60
1.76
0.76
2.7
3.2
0.18
0.23
g/l
—
10
54
5
24
2.15
0.76
2.0
3.3
—
—
—
0
0
22
164
1.46
0.72
7.3
3.8
1.02
1.02
kg/l
0.40
16
106
17
120
1.52
0.72
1.9
1.7
—
—
—
0
0
15
105
1.52
0.65
1.7
1.7
—
—
—
0
0
28
223
1.38
0.64
4.0
3.2
7.60
8.26
mmol/l
0.33
22
196
70
648
1.48
0.61
5.0
4.8
5.88
5.93
mmol/l
0.14
62
607
0
22
0.00
0.60
0.0
12.5
—
—
—
0
0
8
54
1.53
0.59
3.4
2.4
8.61
7.37
ug/l
—
8
49
28
227
1.35
0.57
3.1
3.7
—
—
—
0
0
6
37
1.67
0.57
1.3
1.8
—
—
—
0
0
9
60
1.56
0.57
1.2
1.3
—
—
—
0
0
6
38
1.62
0.55
1.7
2.0
—
—
—
0
0
74
698
1.51
0.51
28.8
15.3
24.10
24.93
mg/l
0.08
65
576
76
722
1.55
0.50
27.9
13.6
—
—
—
0
0
7
48
1.50
0.48
2.9
3.2
—
—
—
0
0
10
69
1.51
0.47
1.5
1.7
—
—
—
0
0
21
168
1.33
0.46
4.3
5.9
—
—
—
0
0
11
78
1.47
0.46
1.5
1.8
—
—
—
0
0
32
273
1.28
0.45
2.3
2.2
90.46
97.66
pmol/l
0.41
20
135
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
2.2
—
3.78
—
0
9
24
203
1.26
0.35
2.4
3.4
14.85
77.35
mg/l
2.81
14
141
7
55
1.30
0.31
3.9
2.0
7.39
7.42
ph
—
7
46
25
216
1.22
0.30
1.6
1.4
—
—
—
0
0
9
116
0.75
0.30
5.1
2.4
18.30
15.19
nmol/l
—
9
111
15
181
0.79
0.29
1.8
3.0
373.80
362.54
umol/l
0.11
15
156
17
202
0.80
0.29
2.6
3.0
0.51
0.79
ug/l
—
10
116
24
208
1.22
0.28
2.8
4.1
2.24
14.02
mg/mmol
3.23
13
133
5
74
0.66
0.27
5.8
4.1
3.72
73.48
ug/l
—
5
58
8
100
0.78
0.22
1.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
5.2
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
205.31
—
0
12
60
623
0.87
0.17
4.6
4.9
2.11
1.90
mu/l
0.31
54
574
9
78
1.17
0.16
3.3
1.6
404.89
400.65
nmol/l
—
9
72
7
85
0.81
0.15
1.3
1.4
—
—
—
0
0
14
159
0.86
0.14
2.3
2.1
—
—
—
0
0
8
77
1.04
0.07
1.5
1.4
—
—
—
0
0
9
87
1.04
0.07
1.3
1.3
—
—
—
0
0
28
294
0.93
0.07
2.0
2.0
1.42
1.38
mmol/l
0.09
23
247
67
681
0.92
0.05
4.2
4.9
1.37
1.37
mmol/l
0.02
62
637
71
701
1.08
0.04
34.6
18.5
139.03
139.65
mmol/l
0.92
71
692
65
657
0.95
0.01
3.4
4.2
1.37
1.33
mmol/l
0.17
60
617
71
704
1.06
0.00
34.7
18.5
3.99
3.98
mmol/l
0.17
71
692
74
738
1.02
0.00
33.6
19.8
85.32
80.40
umol/l
0.30
74
731
5
56
0.89
0.00
1.2
3.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
59
1.02
-0.00
1.2
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.3
—
9.17
—
0
6
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
11.59
—
0
7
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
325.88
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
11.80
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
8
85
0.94
-0.00
1.8
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
73.40
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
159.17
—
0
6
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.1
—
106.22
—
0
9
0
9
0.00
-0.00
0.0
3.1
—
1.20
—
0
9
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
21.44
—
0
9
0
9
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.1
—
4.11
—
0
9
0
9
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
0.34
—
0
9

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ST19_FROST_INVOLVI_MULTIPLE_BODY_REGIONS_UNSPE_FROST – Frostbite involving multiple body regions and unspecified frostbite

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).