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This is a non-core endpoint: only basic statistics are computed.

Crushing injury of lower leg

ST19_CRUSHI_INJURY_LOWER_LEG

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 S87
  • Cause of death: ICD-10 S87

2 out of 7 registries used, show all original rules.

99

4. Check minimum number of events

None

99

5. Include endpoints

None

99

6. Filter based on genotype QC (FinnGen only)

92

Control definitions (FinnGen only)

Control exclude
ST19_INJURI_KNEE_LOWER_LEG

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
S8
Name in latin
Conquassatio genus/cruris

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 92 41 51
Unadjusted period prevalence (%) 0.02 0.01 0.02
Median age at first event (years) 48.95 48.47 49.34

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
92
Matched controls
920
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S87.8
ICD-10 Finland
Crushing injury of other and unspecified parts of lower leg
+∞
77.3
63
*
S87.0
ICD-10 Finland
Crushing injury of knee
+∞
29.8
27
*
S82.8
ICD-10 Finland
Fractures of other parts of lower leg
+∞
20.6
19
*
NHJ10
NOMESCO Finland
Internal fixation of fracture of ankle using wire, rod, cerclage or pin
220.8
18.2
18
*
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
59.0
16.8
19
*
NGJ70
NOMESCO Finland
External fixation of fracture of knee or lower leg, other or unspecified
+∞
13.9
13
*
X58
ICD-10 Finland
Exposure to other specified factors
6.2
13.8
30
67
S80.1
ICD-10 Finland
Contusion of other and unspecified parts of lower leg
74.7
11.9
13
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
4.6
11.8
42
141
ZZA00
NOMESCO Finland
Split skin graft
25.2
11.1
15
7
QDE35
NOMESCO Finland
Repair of skin defect in lower limb after surgery or injury
123.5
10.7
11
*
NGU20
NOMESCO Finland
Removal of internal fixation device from knee or lower leg
123.5
10.7
11
*
NG4AA
NOMESCO Finland
Lower leg X-ray examination
37.3
10.6
13
*
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
14.7
8.7
14
11
S80.0
ICD-10 Finland
Contusion of knee
8.3
8.6
19
28
S82.3
ICD-10 Finland
Fracture of lower end of tibia
+∞
8.5
8
*
S82.2
ICD-10 Finland
Fracture of shaft of tibia
+∞
8.5
8
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
5.2
8.4
20
47
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
24.7
8.2
11
5
ZXE10
NOMESCO Finland
More than one and less than three hours
3.5
8.1
47
212
ZXD05
NOMESCO Finland
Urgent procedure
3.5
8.0
42
177
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
10.3
7.9
15
17
T93.2
ICD-10 Finland
Sequelae of other fractures of lower limb
49.3
7.9
9
*
X59
ICD-10 Finland
Exposure to unspecified factor
4.0
7.8
28
91
M17.3
ICD-10 Finland
Other post-traumatic gonarthrosis
20.5
7.8
11
6
NA1AD
NOMESCO Finland
Cervical spine CT examination
10.8
7.6
14
15
T93.6
ICD-10 Finland
Sequelae of crushing injury and traumatic amputation of lower limb
86.8
7.5
8
*
ZXA00
NOMESCO Finland
Right side
3.5
7.4
36
143
NGQ48
NOMESCO Finland
Revision of exarticulation or amputation stump of knee or lower leg
+∞
7.4
7
*
NGU10
NOMESCO Finland
Removal of external fixation device from knee or lower leg
+∞
7.4
7
*
V49.9
ICD-10 Finland
Car occupant [any] injured in unspecified traffic accident
13.6
7.3
12
10
S22.4
ICD-10 Finland
Multiple fractures of ribs
43.4
6.9
8
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
6.9
6.7
16
27
B01AB05
ATC
enoxaparin; parenteral
3.1
6.4
38
169
NGJ86
NOMESCO Finland
Late operation of fracture of lower leg to promote bone formation
+∞
6.3
6
*
NGJ62
NOMESCO Finland
Internal fixation of fracture of knee or lower leg using plate and screws, other or unspecified
+∞
6.3
6
*
S82.7
ICD-10 Finland
Multiple fractures of lower leg
+∞
6.3
6
*
S82.1
ICD-10 Finland
Fracture of upper end of tibia
+∞
6.3
6
*
Z2446
NOMESCO Finland
Social worker
6.0
6.0
16
31

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
29
136
2.65
4.19
1.3
1.3
28.24
32.97
iu/ml
0.09
12
42
22
91
2.86
4.01
1.1
1.7
—
—
—
0
0
26
119
2.65
3.92
1.4
1.4
4.04
14.22
u/ml
—
10
53
24
117
2.42
3.13
2.0
1.8
—
—
—
0
0
11
35
3.43
2.75
3.9
3.5
37.08
36.94
°c
0.76
11
35
31
179
2.10
2.68
1.8
1.7
0.81
1.48
mg/l
1.00
25
150
37
232
1.99
2.54
4.9
4.5
—
—
—
0
0
21
110
2.18
2.29
1.5
1.4
466.67
531.43
titre
—
6
28
9
32
3.00
2.06
1.8
1.4
—
—
—
0
0
9
33
2.91
1.99
2.2
1.4
—
—
—
0
0
7
22
3.36
1.92
2.0
1.4
—
—
—
0
0
20
111
2.02
1.87
3.8
6.3
104.95
104.85
mmol/l
0.02
20
111
7
24
3.07
1.76
1.4
2.4
—
—
—
0
0
15
77
2.13
1.71
1.5
1.7
—
—
—
0
0
46
342
1.69
1.67
13.7
11.0
0.00
0.00
e9/l
0.50
39
278
11
50
2.36
1.64
4.0
3.8
—
—
—
0
0
9
37
2.58
1.53
1.8
1.5
—
—
—
0
0
9
42
2.26
1.38
1.9
1.5
—
—
—
0
0
24
343
0.59
1.36
3.3
3.2
—
—
—
0
0
9
43
2.21
1.34
1.9
1.4
—
—
—
0
0
9
43
2.21
1.34
1.9
1.4
—
—
—
0
0
48
379
1.56
1.26
8.3
6.7
1.20
1.20
mmol/l
0.22
39
332
6
26
2.40
1.20
1.0
1.4
—
—
—
0
0
68
758
0.61
1.20
5.5
5.0
4.56
4.62
mmol/l
0.18
62
700
0
33
0.00
1.19
0.0
1.1
—
—
—
0
0
32
234
1.56
1.16
2.8
2.5
—
—
—
0
0
36
271
1.54
1.15
3.2
3.2
2.33
2.35
mmol/l
0.44
31
249
20
130
1.69
1.15
3.6
3.1
144.07
466.50
ng/l
0.70
15
97
27
191
1.59
1.12
4.2
4.6
1.02
1.02
kg/l
0.39
20
130
9
46
2.06
1.07
2.8
4.1
—
—
—
0
0
9
47
2.01
1.06
1.2
1.1
—
—
—
0
0
9
49
1.93
1.02
4.6
7.7
25.12
24.86
mmol/l
—
9
49
6
27
2.30
0.95
1.2
1.2
0.32
0.25
g/l
—
6
27
6
27
2.30
0.95
1.2
1.2
1.29
1.24
g/l
—
6
27
69
756
0.65
0.92
5.3
4.9
1.37
1.42
mmol/l
0.42
63
698
8
43
1.94
0.90
2.0
1.5
—
—
—
0
0
65
719
0.67
0.88
5.1
4.2
1.40
1.34
mmol/l
0.32
59
661
53
449
1.43
0.88
12.2
10.4
3.99
4.26
e9/l
0.32
46
394
31
238
1.46
0.87
3.8
3.7
7.40
7.40
ph
0.40
26
172
5
97
0.49
0.84
1.2
1.4
—
—
—
0
0
10
58
1.81
0.83
3.8
3.4
1.23
1.22
mmol/l
—
10
52
71
769
0.66
0.80
6.2
5.6
2.70
2.73
mmol/l
0.11
65
714
6
33
1.87
0.80
1.0
1.1
—
—
—
0
0
41
337
1.39
0.78
3.0
2.8
—
—
estimate
—
0
0
19
256
0.68
0.75
2.8
3.6
0.00
0.00
estimate
—
9
79
33
263
1.40
0.75
3.2
3.0
9.10
62.37
e6/l
1.76
23
195
14
93
1.60
0.75
4.4
7.2
7.36
7.40
ph
—
8
54
5
91
0.52
0.71
1.6
1.3
—
—
—
0
0
5
93
0.51
0.71
1.2
1.5
—
—
—
0
0
37
304
1.36
0.69
3.9
3.6
111.20
72.80
e6/l
0.15
23
207
20
147
1.46
0.69
1.5
1.7
—
—
—
0
0
8
50
1.66
0.63
4.0
9.1
21.59
24.54
mmol/l
—
8
50
58
516
1.34
0.62
3.9
4.5
—
—
—
0
0
17
124
1.46
0.61
1.8
1.7
—
—
—
0
0
13
90
1.52
0.59
1.7
1.3
—
—
—
0
0
6
38
1.62
0.55
2.0
2.7
23.43
24.26
mmol/l
—
6
38
9
62
1.50
0.55
5.2
8.7
—
—
—
0
0
6
39
1.58
0.54
3.0
2.4
1.02
1.46
%
—
6
39
6
39
1.58
0.54
3.0
2.4
0.47
0.60
%
—
6
39
46
403
1.28
0.52
9.3
5.7
0.58
0.58
e9/l
0.02
40
354
46
405
1.27
0.49
9.4
5.7
0.04
0.04
e9/l
0.06
40
355
37
319
1.27
0.46
4.5
3.5
49.91
38.47
ng/l
0.15
29
226
46
409
1.25
0.44
9.5
5.8
1.83
1.85
e9/l
0.08
39
366
27
225
1.28
0.44
3.3
2.9
0.06
0.26
e6/l
2.57
17
158
30
254
1.27
0.43
8.4
5.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
5
34
1.50
0.41
1.2
2.0
26.40
253.62
ng/l
—
5
29
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
48
432
1.23
0.40
3.8
4.1
0.00
0.00
estimate
—
10
104
48
434
1.22
0.38
4.0
4.2
0.00
0.00
estimate
—
10
96
30
260
1.23
0.35
2.6
2.5
59.17
53.86
u/l
0.32
30
246
47
428
1.20
0.33
4.1
4.1
0.00
0.00
estimate
—
9
100
46
421
1.19
0.30
9.6
6.1
0.16
0.18
e9/l
0.34
40
369
19
220
0.83
0.25
1.6
1.5
—
—
—
0
0
34
308
1.16
0.24
2.3
2.1
—
—
—
0
0
31
341
0.86
0.22
2.7
1.9
101.82
94.86
pmol/l
0.35
19
178
37
339
1.15
0.22
3.4
3.8
6.24
6.23
ph
0.02
19
204
5
42
1.20
0.22
3.2
3.0
—
—
—
0
0
0
11
0.00
0.21
0.0
3.1
—
4.87
—
0
11
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
4.6
—
—
—
0
0
0
12
0.00
0.21
0.0
2.8
—
1.17
—
0
12
0
12
0.00
0.21
0.0
2.8
—
3.91
—
0
12
0
12
0.00
0.21
0.0
2.8
—
107.42
—
0
12
33
301
1.15
0.21
4.8
5.0
13.14
1.84
ug/l
0.46
28
271
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
82
798
1.25
0.20
17.8
13.1
—
—
—
0
0
16
185
0.84
0.20
5.1
5.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
7
62
1.14
0.18
1.6
1.4
—
—
—
0
0
19
168
1.17
0.17
1.9
2.2
—
—
—
0
0
20
178
1.16
0.17
1.3
1.3
2.40
2.35
g/l
0.05
12
113
9
79
1.15
0.16
1.7
2.0
—
—
—
0
0
12
106
1.15
0.10
1.3
1.3
—
—
—
0
0
39
372
1.08
0.10
9.5
12.3
1.14
1.22
inr
0.53
33
315
5
48
1.04
0.09
1.4
1.2
—
—
—
0
0
32
336
0.93
0.08
4.1
4.1
0.00
0.03
estimate
—
8
86
23
217
1.08
0.07
3.4
3.3
—
—
—
0
0
21
221
0.94
0.05
3.1
3.4
—
0.33
—
0
6
27
260
1.05
0.04
4.6
3.8
0.00
0.03
estimate
—
9
96
24
231
1.05
0.03
10.4
6.2
—
—
—
0
0
10
108
0.92
0.03
1.5
1.2
—
—
—
0
0
13
135
0.96
0.00
1.7
2.0
16.68
12.78
umol/l
0.59
13
125
11
106
1.04
0.00
1.4
1.2
—
—
—
0
0
12
124
0.96
0.00
1.7
2.1
2.51
2.34
g/l
0.76
12
112
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
8
80
1.00
-0.00
1.4
2.1
344.00
384.07
nmol/l
—
8
75
0
6
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
75
0.93
-0.00
1.9
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
13.1
—
1215.43
—
0
7
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
-0.92
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
137.52
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
0.00
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
1599.50
—
0
6
6
64
0.93
-0.00
1.5
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
42.17
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
72.00
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
1999.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
14.1
—
2717.71
—
0
7

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ST19_CRUSHI_INJURY_LOWER_LEG – Crushing injury of lower leg

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).