No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
439 |
4. Check minimum number of eventsNone |
439 |
5. Include endpointsNone |
439 |
6. Filter based on genotype QC (FinnGen only) |
398 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D35
- Name in latin
- Neoplasma benignum glandulae parathyreoideae
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Parathyroid gland
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of other and unspecified endocrine glands
- Benign neoplasms
- Neoplasms
- Any operation in hilmo
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2464 | 1832 | 617 |
| Only index persons | 2183 | 1635 | 548 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.02 |
| Only index persons | 0.05 | 0.06 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 63.70 | 64.32 | 61.99 |
| Only index persons | 62.91 | 63.38 | 61.51 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 398 | 283 | 115 |
| Unadjusted period prevalence (%) | 0.09 | 0.10 | 0.05 |
| Median age at first event (years) | 61.70 | 60.62 | 64.37 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 407
- Matched controls
- 4070
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
298.1
307.7
220
16
D35.1
ICD-10 Finland
Benign neoplasm: Parathyroid gland
+∞
307.7
374
*
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
83.4
294.7
162
32
E21.0
ICD-10 Finland
Primary hyperparathyroidism
60.7
260.8
153
40
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
58.7
165.4
95
21
E83.50
ICD-10 Finland
Hypercalcemia
38.2
93.5
59
18
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.6
48.1
276
1276
BBA20
NOMESCO Finland
Exploration of parathyroid gland
92.7
45.0
49
6
A11CC03
ATC
alfacalcidol; systemic
12.9
40.9
41
35
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
73.6
35.7
40
6
BAA40
NOMESCO Finland
Unilateral lobectomy of thyroid gland
9.6
35.5
44
51
E21.2
ICD-10 Finland
Other hyperparathyroidism
61.4
33.9
39
7
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.9
32.4
82
199
2271A
ICD-9 Finland
Benign neoplasm of other endocrine glands and related structures, Parathyroid gland
+∞
30.6
29
*
BB1BQ
NOMESCO Finland
Extensive scintigraphy of parathyroid gland, 2 isotopes, SPECT and low-dose CT
89.6
30.2
33
*
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
10.1
27.4
32
34
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.1
26.4
61
136
H05BX01
ATC
cinacalcet; oral
43.3
26.2
32
8
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
7.6
25.0
37
53
2522
FHL
Removal of parathyroidism or multiple parathyroidism (including removal of adenoma or total removal)
138.5
24.9
26
*
321
Kela drug reimbursment
Paricalcitol and cinacalcet
37.1
24.6
31
9
E21
ICD-10 Finland
Hyperparathyroidism and other disorders of parathyroid gland
121.6
21.8
23
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.7
19.2
151
735
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
8.5
19.0
25
31
ZXD10
NOMESCO Finland
Scheduled procedure
2.5
18.5
207
1187
E04.9
ICD-10 Finland
Nontoxic goitre, unspecified
7.9
17.1
24
32
KA1AE
NOMESCO Finland
Kidney ultrasound examination
7.9
17.1
24
32
N18.8
ICD-10 Finland
Other chronic renal failure
7.3
15.4
23
33
KH1AD
NOMESCO Finland
CT of urinary organs
5.3
15.0
31
62
N20.0
ICD-10 Finland
Calculus of kidney
11.5
14.7
27
25
ZXE00
NOMESCO Finland
One hour or less
2.2
13.9
193
1173
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.7
13.3
45
133
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
15.7
13.2
21
14
N20.1
ICD-10 Finland
Calculus of ureter
5.1
13.0
28
58
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
33.2
12.7
16
5
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
10.1
12.4
24
25
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
10.1
11.9
23
24
WX199
NOMESCO Finland
Other local analgesia
4.8
11.8
27
59
N20.9
ICD-10 Finland
Urinary calculus, unspecified
8.7
11.5
24
29
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
18.4
10.8
16
9
KAT00
NOMESCO Finland
Extracorporeal shock wave lithotripsy of pelvis of kidney
18.4
10.8
16
9
K99
ICPC
Cardiovascular disease other
5.5
10.7
21
40
2520A
ICD-9 Finland
Disorders of parathyroid gland, Hyperparathyroidism
112.8
10.5
11
*
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
4.5
10.5
26
61
WX402
NOMESCO Finland
General anaesthesia
2.1
9.8
109
592
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
9.8
176
1138
BA1AE
NOMESCO Finland
Thyroiid ultrasound examination
8.7
9.7
20
24
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
4.3
9.6
25
61
E04.2
ICD-10 Finland
Nontoxic multinodular goitre
3.8
9.4
29
80
106
Kela drug reimbursment
Hypoparathyroidism
37.6
9.1
11
*
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
7.5
8.8
20
28
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.2
8.7
36
121
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
28.2
8.5
11
*
E23.00
ICD-10 Finland
Panhypopituitarism
28.2
8.5
11
*
D44.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Parathyroid gland
+∞
8.4
8
*
V03AE02
ATC
sevelamer; oral
34.1
8.1
10
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.3
8.1
70
342
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
3.9
8.0
24
65
J01MA02
ATC
ciprofloxacin; systemic
1.8
8.0
173
1169
Z71.8
ICD-10 Finland
Other specified counselling
1.8
8.0
161
1065
KH1AA
NOMESCO Finland
Urinary tract X-ray examination without contrast
8.0
8.0
17
22
A12AA04
ATC
calcium carbonate; oral
7.7
7.7
17
23
E66.8
ICD-10 Finland
Other obesity
3.3
7.7
29
92
Z94.0
ICD-10 Finland
Kidney transplant status
18.8
7.6
11
6
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.4
7.6
58
268
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.0
7.6
101
581
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.1
7.6
86
467
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.6
7.6
45
185
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
13.7
7.4
12
9
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.9
7.3
103
603
I10
ICD-10 Finland
Essential (primary) hypertension
1.8
7.3
287
2295
XCH00
NOMESCO Finland
Eye pressure measurement
3.0
7.2
33
118
196
Kela drug reimbursment
Paricalcitol and cinacalcet
30.6
7.2
9
*
A11CC02
ATC
dihydrotachysterol; oral
30.6
7.2
9
*
E21.1
ICD-10 Finland
Secondary hyperparathyroidism, not elsewhere classified
20.4
7.2
10
5
101
Kela drug reimbursment
Anterior pituitary hypofunction
20.4
7.2
10
5
E21.5
ICD-10 Finland
Disorder of parathyroid gland, unspecified
20.4
7.2
10
5
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
3.4
7.1
26
81
127
Kela drug reimbursment
Transplant complication
10.3
7.1
13
13
M04AA01
ATC
allopurinol; systemic
2.2
7.1
64
318
KBE12
NOMESCO Finland
Transluminal endoscopic extraction of calculus of ureter
11.2
6.8
12
11
Z49.0
ICD-10 Finland
Preparatory care for dialysis
11.2
6.8
12
11
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.7
6.7
38
152
H03AA01
ATC
levothyroxine sodium; systemic
1.8
6.7
119
749
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
22.9
6.7
9
*
BA3AT
NOMESCO Finland
Cytology of thyroid with ultrasound quidance
6.1
6.7
17
29
R4110, ,
SPAT
2.0
6.6
74
399
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
6.6
162
1121
D34
ICD-10 Finland
Benign neoplasm of thyroid gland
14.6
6.4
10
7
Z49.1
ICD-10 Finland
Extracorporeal dialysis
8.4
6.4
13
16
N06AX16
ATC
venlafaxine; oral
2.1
6.4
68
360
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
9.5
6.3
12
13
N30.0
ICD-10 Finland
Acute cystitis
1.9
6.3
86
497
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
7.2
6.3
14
20
C75.0
ICD-10 Finland
Malignant neoplasm: Parathyroid gland
+∞
6.3
6
*
BBA50
NOMESCO Finland
Total parathyroidectomy
+∞
6.3
6
*
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
27.1
6.2
8
*
H02AB09
ATC
hydrocortisone; systemic
4.1
6.2
17
43
D64.9
ICD-10 Finland
Anaemia, unspecified
2.2
6.1
53
258
M05BA04
ATC
alendronic acid; oral
2.2
6.1
54
266
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
135
76
26.08
175.34
2.2
1.7
6.83
3.80
mmol/24h
8.51
116
65
215
320
13.12
154.97
6.9
3.4
118.59
82.15
ng/l
2.92
194
280
191
494
6.40
75.83
10.5
5.1
0.93
1.06
mmol/l
5.39
179
461
350
2046
6.07
42.15
20.5
6.8
1.27
1.21
mmol/l
19.32
328
1781
37
26
15.55
41.29
2.9
1.7
145.59
82.03
ng/l
0.95
37
26
322
1789
4.83
40.78
4.6
2.5
79.05
80.58
nmol/l
0.49
306
1591
69
138
5.82
34.04
3.3
1.7
—
—
—
0
0
72
150
5.62
33.99
3.4
1.9
—
—
—
0
0
48
83
6.42
27.31
4.9
3.0
11.12
9.14
pmol/l
0.60
48
83
255
1434
3.08
26.60
4.1
3.5
2.44
2.36
mmol/l
7.25
235
1293
179
863
2.92
24.18
3.4
3.1
2.53
2.46
mmol/l
4.74
169
778
279
1769
2.84
21.24
8.8
4.6
36.27
35.52
g/l
1.97
266
1662
180
944
2.63
19.73
3.3
2.4
—
—
—
0
0
258
1767
2.26
13.76
3.4
2.8
—
—
estimate
—
0
0
27
52
5.49
13.62
1.4
1.2
0.18
0.19
nmol/l
0.25
19
35
157
884
2.26
13.57
5.6
2.6
4.15
5.94
e6/l
1.03
150
805
136
759
2.19
11.71
4.7
4.2
105.05
340.82
ng/l
1.54
99
611
64
260
2.73
11.07
5.4
3.4
5.14
5.13
kpa
0.02
64
253
121
670
2.15
10.45
2.4
2.0
—
—
—
0
0
286
2161
2.09
10.34
9.3
9.9
4.11
4.11
e9/l
0.01
249
1883
353
2929
2.55
9.70
12.6
8.4
86.29
79.02
u/l
0.67
344
2760
53
214
2.70
9.24
4.1
3.5
1.39
1.99
mmol/l
0.62
44
162
250
1849
1.91
9.01
12.5
6.0
1.26
1.22
mmol/l
12.26
242
1699
43
158
2.92
8.93
2.9
2.1
2.54
3.04
g/l
2.11
36
148
156
995
1.92
8.84
5.0
2.8
359.77
337.47
umol/l
2.06
146
869
45
174
2.78
8.51
2.8
2.0
3.47
3.75
g/l
0.52
38
164
45
174
2.78
8.51
2.8
2.0
4.45
4.22
g/l
1.05
38
164
45
174
2.78
8.51
2.8
2.0
7.70
7.47
g/l
0.38
38
164
63
293
2.36
8.16
3.5
3.3
231.50
221.68
ng/l
0.05
58
271
117
694
1.96
8.11
2.0
1.7
974.84
1227.34
nmol/l
2.53
96
518
187
1291
1.83
8.08
6.0
3.2
102.65
90.32
e6/l
0.06
164
976
335
2803
2.10
7.64
7.4
4.7
15.12
12.78
mm/h
1.88
324
2601
11
6
18.79
7.64
1.5
1.0
1.28
1.18
mmol/l
—
11
6
193
1365
1.79
7.55
5.3
3.4
7.27
7.01
mmol/l
0.30
168
1128
74
381
2.15
7.49
12.2
3.3
2.01
2.23
mmol/l
0.20
65
332
285
2285
1.82
7.05
7.5
4.8
6.55
6.68
mmol/l
0.67
278
2172
38
149
2.71
7.00
2.2
2.0
10.29
10.44
g/l
0.05
31
138
180
1270
1.75
6.93
4.4
2.4
63.34
65.04
u/l
0.08
168
1170
148
997
1.76
6.64
3.7
2.2
2.43
3.12
mg/l
4.40
133
863
68
357
2.09
6.51
2.0
3.0
67.61
66.60
g/l
0.50
57
336
106
651
1.85
6.44
4.8
3.0
0.81
0.82
mmol/l
0.22
101
621
33
127
2.74
6.31
2.4
4.2
1.51
2.73
ratio
1.05
23
71
29
104
2.93
6.30
1.2
1.3
—
—
—
0
0
233
1797
1.69
6.26
2.5
2.2
101.97
97.29
pmol/l
0.58
133
899
131
868
1.75
6.14
1.7
1.7
1.08
1.36
mg/l
0.72
103
686
14
22
6.55
5.91
1.7
1.5
93.07
77.50
umol/l
0.69
14
22
39
175
2.36
5.46
2.6
2.4
41.31
40.82
u/l
0.05
32
156
183
1359
1.63
5.44
6.0
4.2
9.69
8.42
mg/mmol
0.21
127
808
236
1887
1.60
5.02
18.7
14.3
1.28
1.23
inr
0.59
210
1563
333
2920
1.77
4.75
6.2
4.5
14.47
14.92
pmol/l
2.45
313
2669
7
5
14.21
4.59
1.1
2.0
—
—
—
0
0
14
32
4.49
4.48
1.3
1.2
111.07
106.91
pmol/l
0.10
14
32
372
3401
2.09
4.33
7.6
5.7
1.81
1.95
mu/l
1.71
352
3123
378
3485
2.19
4.16
28.4
16.7
72.26
77.38
ml/min/173m2
3.97
365
3238
254
2116
1.53
4.13
7.5
6.6
12.32
11.26
umol/l
0.39
243
2015
12
26
4.72
4.09
1.8
1.7
—
—
—
0
0
12
26
4.72
4.09
1.8
1.7
—
—
—
0
0
12
26
4.72
4.09
1.8
1.7
—
—
—
0
0
12
26
4.72
4.09
1.8
1.7
—
—
—
0
0
217
1751
1.51
4.08
5.0
3.0
161.97
128.51
ug/l
1.07
207
1622
74
465
1.72
4.04
4.1
5.0
229.48
266.93
u/l
0.99
69
439
9
15
6.11
3.83
2.0
2.2
—
—
—
0
0
14
45
3.19
3.68
1.7
1.7
—
—
—
0
0
14
45
3.19
3.68
1.7
1.7
—
—
—
0
0
14
45
3.19
3.68
1.7
1.7
—
—
—
0
0
162
1252
1.49
3.64
2.5
2.1
207.17
183.27
u/l
0.11
151
1183
101
705
1.58
3.64
1.4
1.3
6.51
11.31
u/ml
0.41
46
270
17
63
2.77
3.53
1.4
1.3
—
—
—
0
0
144
1096
1.49
3.46
5.0
3.2
0.29
0.46
e6/l
0.75
117
784
9
18
5.09
3.39
1.9
1.8
40.67
53.14
ug/l
—
9
18
90
622
1.57
3.37
5.4
2.5
2.26
2.34
g/l
0.73
85
576
8
15
5.42
3.20
3.5
6.7
—
—
—
0
0
7
11
6.45
3.19
2.4
1.2
101.57
56.18
nmol/24h
—
7
11
15
57
2.69
3.00
1.3
1.4
—
—
—
0
0
272
2373
1.44
2.99
4.1
3.3
58.59
49.49
u/l
0.69
259
2207
236
2011
1.41
2.93
2.8
2.8
—
—
—
0
0
105
773
1.48
2.91
1.4
1.3
52.76
36.59
iu/ml
0.33
28
254
15
58
2.65
2.90
1.3
1.4
—
—
—
0
0
377
3545
1.86
2.78
28.1
16.7
26.76
23.52
mg/l
1.17
336
2940
6
11
5.52
2.55
1.3
1.3
132.70
122.32
iu/ml
—
6
11
14
58
2.46
2.39
1.2
1.4
—
—
—
0
0
36
215
1.74
2.38
3.6
2.5
13.87
13.03
nmol/l
0.30
36
199
115
898
1.39
2.27
1.3
1.3
2.45
1.77
u/ml
0.16
26
230
14
61
2.34
2.17
2.7
1.2
—
—
—
0
0
9
31
2.95
2.08
7.2
2.7
—
—
—
0
0
5
10
5.05
2.07
1.2
1.7
0.62
0.62
mmol/l
—
5
10
11
44
2.54
2.03
2.8
2.1
-0.54
0.19
mmol/l
0.17
11
44
10
39
2.60
1.95
1.0
1.1
—
—
—
0
0
48
329
1.52
1.88
4.4
2.7
60.13
64.71
ml/min/173m2
0.44
30
147
43
289
1.55
1.84
1.9
1.6
—
—
—
0
0
145
1209
1.31
1.81
1.8
1.7
20.13
21.28
nmol/l
0.43
122
1010
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
20
109
1.88
1.80
2.7
2.3
0.30
0.39
iu/ml
0.48
12
61
17
90
1.93
1.67
1.2
1.3
—
—
—
0
0
25
150
1.71
1.67
1.5
2.3
0.38
0.99
g/l
0.82
18
136
5
15
3.36
1.53
1.0
4.3
202.00
227.07
u/l
—
5
15
12
58
2.10
1.50
1.4
1.2
—
—
—
0
0
21
124
1.73
1.50
1.4
1.4
258.89
297.76
ug/g
0.36
12
75
363
3467
1.43
1.47
8.6
6.9
39.52
39.68
mmol/mol
0.14
347
3236
21
128
1.68
1.36
1.1
1.3
—
—
—
0
0
367
3521
1.43
1.35
6.4
5.6
5.98
5.99
mmol/l
0.01
347
3223
10
48
2.11
1.28
1.3
1.4
—
—
—
0
0
83
671
1.30
1.28
5.5
5.0
24.02
21.60
%
0.45
36
342
48
357
1.39
1.28
3.4
6.6
1.06
1.28
mmol/l
2.10
48
352
51
385
1.37
1.25
2.9
3.6
—
—
—
0
0
5
19
2.65
1.22
1.4
1.6
—
—
—
0
0
374
3611
1.44
1.21
6.8
6.4
2.70
2.70
mmol/l
0.03
359
3324
5
20
2.52
1.15
1.4
1.5
—
—
—
0
0
11
58
1.92
1.13
1.5
1.1
301.17
265.93
u/ml
—
6
27
8
40
2.02
1.12
1.9
1.2
—
—
—
0
0
14
230
0.59
1.10
1.4
2.0
3.66
3.46
mmol/l
—
8
177
56
440
1.32
1.07
2.8
2.6
13.17
7.45
umol/l
0.44
49
394
368
3556
1.36
1.05
6.0
5.5
4.68
4.68
mmol/l
0.00
356
3278
35
469
0.72
1.05
9.9
7.3
—
—
—
0
0
366
3536
1.35
1.03
6.0
5.4
1.46
1.53
mmol/l
2.71
350
3246
17
107
1.61
1.01
1.6
1.6
—
—
—
0
0
22
315
0.68
0.96
1.5
2.2
3.96
3.39
ratio
1.24
17
262
98
837
1.23
0.96
1.8
1.8
590.24
17006274.07
pmol/l
0.50
88
688
6
27
2.24
0.94
1.3
1.5
—
—
—
0
0
9
52
1.75
0.93
1.0
1.2
—
—
—
0
0
6
28
2.16
0.92
1.0
1.0
—
—
—
0
0
15
94
1.62
0.92
1.5
1.7
7.07
68.13
iu/l
—
5
36
77
911
0.81
0.91
5.9
4.4
1.02
1.02
kg/l
0.17
58
616
10
56
1.81
0.88
1.3
1.4
—
—
—
0
0
10
56
1.81
0.88
1.3
1.4
—
—
—
0
0
10
57
1.77
0.84
1.3
1.4
—
—
—
0
0
98
851
1.20
0.81
6.8
6.0
2.11
2.79
ug/l
0.65
89
756
6
33
1.83
0.79
1.5
1.1
—
—
—
0
0
0
25
0.00
0.79
0.0
1.2
—
—
—
0
0
8
48
1.68
0.79
1.5
1.5
—
—
—
0
0
350
3386
1.24
0.78
5.3
4.6
1.40
1.27
mmol/l
3.10
328
3085
220
2049
1.16
0.77
4.4
4.1
0.00
0.00
estimate
-0.00
43
427
104
1176
0.84
0.76
5.7
4.2
0.00
0.00
estimate
0.50
40
404
32
245
1.33
0.76
1.5
1.8
—
—
—
0
0
383
3748
1.37
0.76
17.7
13.0
25.11
24.57
u/l
0.37
374
3640
223
2083
1.16
0.74
4.7
4.2
0.00
0.75
estimate
0.51
42
411
5
25
2.01
0.73
1.4
1.5
—
—
—
0
0
55
456
1.24
0.72
3.9
4.4
13.31
16.23
ug/l
0.09
48
381
16
110
1.47
0.69
1.3
1.2
—
—
—
0
0
11
69
1.61
0.69
1.5
1.7
—
—
—
0
0
122
1096
1.16
0.68
4.1
3.5
0.00
0.07
estimate
0.50
35
347
23
171
1.37
0.67
2.1
2.0
9.43
7.17
iu/ml
—
6
44
16
111
1.46
0.67
1.9
1.5
18461.00
19700.20
e6/l
0.05
11
80
5
28
1.80
0.66
4.0
2.6
596.20
571.73
ml
—
5
15
220
2066
1.14
0.65
4.8
4.1
0.00
3.68
estimate
0.50
44
441
6
105
0.57
0.62
1.7
1.5
—
—
—
0
0
5
30
1.67
0.61
1.2
1.1
—
—
—
0
0
6
37
1.63
0.55
1.0
1.1
—
—
—
0
0
13
91
1.44
0.53
1.1
1.1
—
5.66
—
0
9
6
40
1.51
0.52
1.0
1.1
—
—
—
0
0
12
84
1.44
0.50
1.8
1.5
—
—
—
0
0
15
112
1.35
0.45
1.6
1.3
—
—
—
0
0
57
500
1.16
0.45
1.9
1.9
—
—
—
0
0
144
1540
0.90
0.45
4.2
4.1
40.35
74.97
ng/l
0.44
107
1158
27
220
1.24
0.45
3.4
8.4
16.95
15.84
%
1.55
27
213
14
104
1.36
0.43
1.6
1.7
—
—
—
0
0
6
93
0.64
0.42
1.0
1.2
1.42
1.59
g/l
—
6
93
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
156
1654
0.91
0.40
1.9
2.0
1.38
1.33
mmol/l
0.40
127
1368
5
34
1.48
0.40
2.2
1.2
—
—
—
0
0
69
620
1.14
0.40
3.6
3.0
2.98
2.93
e6/l
0.02
35
287
18
143
1.27
0.37
2.4
2.7
—
—
—
0
0
5
37
1.36
0.37
1.2
1.1
—
—
—
0
0
19
234
0.80
0.37
1.4
1.8
—
—
—
0
0
53
472
1.14
0.36
1.9
2.0
—
—
—
0
0
17
210
0.80
0.34
1.4
1.7
—
—
—
0
0
24
201
1.21
0.33
2.4
1.4
—
—
—
0
0
16
128
1.26
0.32
1.3
1.6
—
—
—
0
0
21
251
0.83
0.32
3.6
6.8
24.89
24.57
mmol/l
0.16
21
240
7
98
0.71
0.31
1.0
1.2
1.05
0.91
g/l
—
7
98
23
194
1.20
0.30
2.5
4.5
1.31
1.54
%
1.89
23
186
61
561
1.10
0.26
1.4
1.5
—
—
—
0
0
9
73
1.24
0.25
1.1
1.3
—
—
—
0
0
9
73
1.24
0.25
1.1
1.3
—
—
—
0
0
63
583
1.10
0.24
1.4
1.5
—
—
—
0
0
5
40
1.25
0.22
1.2
1.9
—
—
—
0
0
5
41
1.22
0.22
1.2
1.6
—
26.83
—
0
6
50
460
1.10
0.22
3.1
7.2
0.87
1.08
mmol/l
0.15
40
391
0
11
0.00
0.21
0.0
2.1
—
2.88
—
0
5
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
137
1315
1.06
0.21
3.8
3.2
3881.40
1239.10
ng/l
1.18
121
1128
51
471
1.09
0.21
3.2
7.1
5.29
5.09
kpa
0.73
51
457
51
471
1.09
0.21
3.2
7.1
12.46
11.95
kpa
0.32
51
457
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
12
99
1.22
0.20
1.1
1.6
—
—
—
0
0
40
367
1.10
0.19
1.5
1.7
1.46
1.52
%
0.25
34
316
13
109
1.20
0.19
1.2
1.7
—
—
—
0
0
16
185
0.86
0.18
1.3
1.3
—
—
—
0
0
7
63
1.11
0.17
1.6
1.6
—
—
—
0
0
12
103
1.17
0.14
2.6
3.4
0.01
1.82
index
—
6
61
71
681
1.05
0.12
3.6
2.9
1.08
1.02
e6/l
0.07
38
346
36
382
0.94
0.10
3.4
2.4
36.19
36.26
u/l
0.01
31
317
42
398
1.06
0.10
3.5
7.5
123.48
120.19
g/l
0.53
42
392
5
44
1.14
0.10
1.2
1.8
—
—
—
0
0
10
114
0.87
0.09
1.6
1.5
—
—
—
0
0
53
510
1.05
0.08
4.2
3.4
0.83
0.79
ug/l
0.13
40
343
8
77
1.04
0.07
1.4
1.2
60.13
25.04
u/l
—
8
64
9
84
1.07
0.07
1.7
1.5
—
—
—
0
0
10
89
1.13
0.07
1.6
1.7
—
—
—
0
0
8
93
0.86
0.07
1.3
1.2
—
—
—
0
0
11
99
1.11
0.06
1.4
1.4
—
—
—
0
0
24
227
1.06
0.06
2.6
2.4
0.54
0.62
%
1.20
24
227
31
323
0.96
0.05
1.3
1.5
—
—
—
0
0
12
110
1.09
0.05
1.4
1.6
—
—
—
0
0
15
140
1.07
0.04
2.4
3.9
1.21
1.33
mmol/l
0.36
15
134
14
131
1.07
0.03
1.9
1.4
0.21
0.34
mg/l
—
5
54
51
502
1.02
0.01
6.8
5.2
33.56
32.78
%
0.21
39
310
155
1543
1.01
0.01
4.5
4.1
0.06
0.03
estimate
0.24
32
348
11
112
0.98
0.00
1.1
1.5
—
—
—
0
0
12
118
1.02
0.00
1.3
1.2
—
—
—
0
0
12
118
1.02
0.00
1.3
1.2
—
—
—
0
0
14
141
0.99
0.00
2.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
8.4
—
9.62
—
0
5
0
9
0.00
-0.00
0.0
1.9
—
1.20
—
0
9
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
98
0.92
-0.00
1.2
1.3
444.33
546.04
mg/l
—
9
93
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
9
96
0.94
-0.00
1.7
1.5
—
—
—
0
0
8
81
0.99
-0.00
1.5
1.6
—
—
—
0
0
18
180
1.00
-0.00
1.1
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
87
0.92
-0.00
1.1
1.2
3.53
3.76
mmol/l
—
8
82
0
7
0.00
-0.00
0.0
1.4
—
49.29
—
0
7
5
50
1.00
-0.00
1.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.0
1.1
—
—
—
0
0
5
50
1.00
-0.00
1.6
1.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_PARATHYROID and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_PARATHYROID | 1.159 [1.0, 1.35] | 0.058 |
| Birth year | 0.995 [0.99, 1.0] | 0.266 |
During the follow-up period (1.1.1998 — 31.12.2019), 274 out of 1306 females with CD2_BENIGN_PARATHYROID died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_PARATHYROID | 1.321 [1.02, 1.71] | 0.035 |
| Birth year | 0.989 [0.98, 1.0] | 0.021 |
During the follow-up period (1.1.1998 — 31.12.2019), 101 out of 462 males with CD2_BENIGN_PARATHYROID died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_PARATHYROID.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.131% | 0.225% |
| 5 | 0.641% | 1.462% |
| 10 | 1.589% | 3.921% |
| 15 | 3.173% | 7.784% |
| 20 | 5.666% | 13.282% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_PARATHYROID – Benign neoplasm: Parathyroid gland
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data