No definition available.
Trisomy 21 (Down syndrome) due to meiotic nondisjunction
Q17_TRISOMY_21_DUE_TO_MEIOTIC_NONDISJUNCTION
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
73 |
4. Check minimum number of eventsNone |
73 |
5. Include endpointsNone |
73 |
6. Filter based on genotype QC (FinnGen only) |
68 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Trisomy 21 (Down syndrome) due to meiotic nondisjunction
based on the number of shared cases.
Similar with more cases:
- Down's syndrome
- Chromosomal abnormalities, not elsewhere classified
- Clefts and syndromes for tooth agenesis exclusion, including avohilmo
- Congenital malformations, deformations and chromosomal abnormalities
- Congenital malformations, deformations and chromosomal abnormalities
Similar with less cases:
None
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: unknown.
No upset table: unknown.
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 68 | 42 | 26 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 18.96 | 30.35 | 0.56 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 73
- Matched controls
- 730
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q900, ,
ICD-10 Finland
Trisomy 21, meiotic nondisjunction
+∞
104.9
73
*
A98, ,
ICD-O-3
+∞
90.6
67
*
J01CA04, ,
ATC
amoxicillin; systemic
+∞
84.7
64
*
J01DB01, ,
ATC
cefalexin; oral
+∞
70.7
56
*
SAA02, ,
ICD-O-3
+∞
67.5
54
*
SAA01, ,
ICD-O-3
+∞
61.3
50
*
WX110, ,
ICD-O-3
+∞
56.9
47
*
Q909, ,
ICD-10 Finland
Down syndrome, unspecified
+∞
55.4
46
*
J069, ,
ICD-O-3
+∞
49.8
42
*
J01CR02, ,
ATC
amoxicillin and beta-lactamase inhibitor; systemic
+∞
48.4
41
*
Z012, ,
ICD-O-3
+∞
45.7
39
*
J01FA10, ,
ATC
azithromycin; systemic
+∞
45.7
39
*
SAA03, ,
ICD-O-3
+∞
44.4
38
*
M01AE01, ,
ATC
ibuprofen; systemic, rectal
+∞
43.0
37
*
SCA01, ,
ICD-O-3
+∞
43.0
37
*
GD1AA, ,
ICD-O-3
+∞
41.7
36
*
E0000UV, ,
ATC
+∞
40.4
35
*
N02BE01, ,
ATC
paracetamol; systemic, rectal
+∞
40.4
35
*
ZXD10, ,
ICD-O-3
+∞
39.1
34
*
WZC00, ,
ICD-O-3
+∞
37.8
33
*
J01CE02, ,
ATC
phenoxymethylpenicillin; oral
+∞
37.8
33
*
J01DA01, ,
ATC
[U] cefalexin
+∞
36.6
32
*
R03AC02, ,
ATC
salbutamol; inhalant
+∞
35.3
31
*
M01AE02, ,
ATC
naproxen; oral, rectal
+∞
34.0
30
*
J01AA02, ,
ATC
doxycycline; systemic
+∞
34.0
30
*
SFA10, ,
ICD-O-3
+∞
34.0
30
*
H03AA01, ,
ATC
levothyroxine sodium; systemic
+∞
34.0
30
*
K021, ,
ICD-O-3
+∞
34.0
30
*
ZXE00, ,
ICD-O-3
+∞
32.8
29
*
EB1AA, ,
ICD-O-3
+∞
32.8
29
*
ZXE10, ,
ICD-O-3
+∞
32.8
29
*
EBA00, ,
ICD-O-3
+∞
32.8
29
*
J01EE02, ,
ATC
sulfadiazine and trimethoprim; systemic
+∞
31.6
28
*
A02BC02, ,
ATC
pantoprazole; systemic
+∞
31.6
28
*
J069, ,
ICD-10 Finland
Acute upper respiratory infection, unspecified
+∞
30.3
27
*
WX408, ,
ICD-O-3
+∞
30.3
27
*
SFA20, ,
ICD-O-3
+∞
30.3
27
*
EB1HA, ,
ICD-O-3
+∞
30.3
27
*
-1, ,
ICD-O-3
+∞
29.1
26
*
EB1SA, ,
ICD-O-3
+∞
29.1
26
*
WYA05, ,
ICD-O-3
+∞
29.1
26
*
SDA03, ,
ICD-O-3
+∞
29.1
26
*
KMAK, ,
ICD-O-3
+∞
29.1
26
*
K0364, ,
ICD-O-3
+∞
27.9
25
*
Z2221, ,
ICD-O-3
+∞
27.9
25
*
DCA20, ,
ICD-O-3
+∞
27.9
25
*
Z3231, ,
ICD-O-3
+∞
27.9
25
*
SPAT1263, ,
ICD-O-3
+∞
27.9
25
*
SPAT1315, ,
ICD-O-3
+∞
26.7
24
*
SDA02, ,
ICD-O-3
+∞
26.7
24
*
WX402, ,
ICD-O-3
+∞
26.7
24
*
J01FA06, ,
ATC
roxithromycin; oral
+∞
25.5
23
*
WX404, ,
ICD-O-3
+∞
25.5
23
*
R01AD09, ,
ATC
mometasone; nasal
+∞
24.3
22
*
P85, ,
ICD-O-3
+∞
24.3
22
*
H02AB06, ,
ATC
prednisolone; systemic
+∞
24.3
22
*
WX290, ,
ICD-O-3
+∞
24.3
22
*
UDC00, ,
ICD-O-3
+∞
23.1
21
*
SDA01, ,
ICD-O-3
+∞
23.1
21
*
R74, ,
ICD-O-3
+∞
23.1
21
*
WZB00, ,
ICD-O-3
+∞
23.1
21
*
SPAT1325, ,
ICD-O-3
+∞
23.1
21
*
SCA02, ,
ICD-O-3
+∞
23.1
21
*
H653, ,
ICD-10 Finland
Chronic mucoid otitis media
+∞
23.1
21
*
SPAT1317, ,
ICD-O-3
+∞
23.1
21
*
UJD10, ,
ICD-O-3
+∞
23.1
21
*
Z3226, ,
ICD-O-3
+∞
22.0
20
*
J189, ,
ICD-10 Finland
Pneumonia, unspecified
+∞
22.0
20
*
R06AE07, ,
ATC
cetirizine; oral
+∞
22.0
20
*
VALMI, ,
ICD-O-3
+∞
22.0
20
*
XF400, ,
ICD-O-3
+∞
22.0
20
*
Z010, ,
ICD-10 Finland
Examination of eyes and vision
+∞
22.0
20
*
ZXD05, ,
ICD-O-3
+∞
22.0
20
*
Z011, ,
ICD-10 Finland
Examination of ears and hearing
+∞
22.0
20
*
WX700, ,
ICD-O-3
+∞
22.0
20
*
ZXA10, ,
ICD-O-3
+∞
20.8
19
*
Z001, ,
ICD-O-3
+∞
20.8
19
*
SPAT1249, ,
ICD-O-3
+∞
20.8
19
*
Z871, ,
ICD-O-3
+∞
20.8
19
*
P01AB01, ,
ATC
metronidazole; oral, rectal
+∞
20.8
19
*
FM1EE, ,
ICD-O-3
+∞
20.8
19
*
R83, ,
ICD-O-3
+∞
20.8
19
*
D82, ,
ICD-O-3
+∞
20.8
19
*
J01FA09, ,
ATC
clarithromycin; systemic
+∞
20.8
19
*
WYA30, ,
ICD-O-3
+∞
20.8
19
*
SDE02, ,
ICD-O-3
+∞
19.7
18
*
R104, ,
ICD-10 Finland
Other and unspecified abdominal pain
+∞
19.7
18
*
Q900, ,
ICD-O-3
+∞
19.7
18
*
H660, ,
ICD-10 Finland
Acute suppurative otitis media
+∞
19.7
18
*
JN3AE, ,
ICD-O-3
+∞
19.7
18
*
M01AH05, ,
ATC
etoricoxib; oral
+∞
19.7
18
*
SPAT1256, ,
ICD-O-3
+∞
19.7
18
*
R4110, ,
ICD-O-3
+∞
19.7
18
*
O800, ,
ICD-10 Finland
Spontaneous vertex delivery
+∞
18.5
17
*
A03, ,
ICD-O-3
+∞
18.5
17
*
SPAT1312, ,
ICD-O-3
+∞
18.5
17
*
Q90, ,
ICD-O-3
+∞
18.5
17
*
M03BX02, ,
ATC
tizanidine; oral
+∞
18.5
17
*
SAB01, ,
ICD-O-3
+∞
18.5
17
*
WZA90, ,
ICD-O-3
+∞
18.5
17
*
R06AX27, ,
ATC
desloratadine; oral
+∞
18.5
17
*
TPH04, ,
ICD-O-3
+∞
17.4
16
*
SDA04, ,
ICD-O-3
+∞
17.4
16
*
R05, ,
ICD-O-3
+∞
17.4
16
*
SPAT1301, ,
ICD-O-3
+∞
17.4
16
*
SAB03, ,
ICD-O-3
+∞
17.4
16
*
D01BA02, ,
ATC
terbinafine; oral
+∞
17.4
16
*
SPAT1253, ,
ICD-O-3
+∞
17.4
16
*
ZXD20, ,
ICD-O-3
+∞
17.4
16
*
SPAT1310, ,
ICD-O-3
+∞
17.4
16
*
7580A, ,
ICD-9 Finland
Chromosomal anomalies, Down's syndrome
+∞
17.4
16
*
R03BA05, ,
ATC
fluticasone; inhalant
+∞
17.4
16
*
R5110, ,
ICD-O-3
+∞
17.4
16
*
Z018, ,
ICD-10 Finland
Other specified special examinations
+∞
16.2
15
*
J01FF01, ,
ATC
clindamycin; systemic
+∞
16.2
15
*
WW200, ,
ICD-O-3
+∞
16.2
15
*
GD1UA, ,
ICD-O-3
+∞
16.2
15
*
J02AC01, ,
ATC
fluconazole; systemic
+∞
16.2
15
*
S18, ,
ICD-O-3
+∞
16.2
15
*
H660, ,
ICD-O-3
+∞
16.2
15
*
O049, ,
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
+∞
16.2
15
*
A02BC01, ,
ATC
omeprazole; systemic
+∞
16.2
15
*
FM1AE, ,
ICD-O-3
+∞
16.2
15
*
J01DA09, ,
ATC
[U] cefadroxil
+∞
15.1
14
*
R01AD58, ,
ATC
fluticasone, combinations; nasal
+∞
15.1
14
*
S01XA20, ,
ATC
artificial tears and other indifferent preparations; ophthalmic
+∞
15.1
14
*
J01CA08, ,
ATC
pivmecillinam; oral
+∞
15.1
14
*
M01AB05, ,
ATC
diclofenac; systemic, rectal
+∞
15.1
14
*
AA1AD, ,
ICD-O-3
+∞
15.1
14
*
SPAT1324, ,
ICD-O-3
+∞
15.1
14
*
D07AA02, ,
ATC
hydrocortisone; topical
+∞
15.1
14
*
G03CA03, ,
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
+∞
15.1
14
*
B01AB05, ,
ATC
enoxaparin; parenteral
+∞
15.1
14
*
Z363, ,
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
+∞
14.0
13
*
ZXA00, ,
ICD-O-3
+∞
14.0
13
*
WX882, ,
ICD-O-3
+∞
14.0
13
*
L17, ,
ICD-O-3
+∞
14.0
13
*
H669, ,
ICD-O-3
+∞
14.0
13
*
D19, ,
ICD-O-3
+∞
14.0
13
*
A02BC03, ,
ATC
lansoprazole; oral
+∞
14.0
13
*
SFA30, ,
ICD-O-3
+∞
14.0
13
*
R21, ,
ICD-O-3
+∞
14.0
13
*
A12AX, ,
ATC
Calcium, combinations with vitamin D and/or other drugs
+∞
14.0
13
*
R01AD12, ,
ATC
fluticasone furoate; nasal
+∞
14.0
13
*
W01, ,
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
+∞
14.0
13
*
N02AA59, ,
ATC
codeine, combinations excl. psycholeptics; systemic
+∞
14.0
13
*
R065, ,
ICD-10 Finland
Mouth breathing
+∞
12.9
12
*
SPAT1283, ,
ICD-O-3
+∞
12.9
12
*
J01MA02, ,
ATC
ciprofloxacin; systemic
+∞
12.9
12
*
EMB30, ,
ICD-O-3
+∞
12.9
12
*
D07AC01, ,
ATC
betamethasone; topical
+∞
12.9
12
*
Q2110, ,
ICD-10 Finland
Persistent ostium secundum
+∞
12.9
12
*
D01AC20, ,
ATC
imidazoles/triazoles in combination with corticosteroids; topical
+∞
12.9
12
*
D07AB02, ,
ATC
hydrocortisone butyrate; topical
+∞
12.9
12
*
D07AC13, ,
ATC
mometasone; topical
+∞
12.9
12
*
SAD01, ,
ICD-O-3
+∞
12.9
12
*
201, ,
Kela drug reimbursment
Chronic cardiac insufficiency
+∞
12.9
12
*
OAA40, ,
ICD-O-3
+∞
12.9
12
*
SFC01, ,
ICD-O-3
+∞
12.9
12
*
H669, ,
ICD-10 Finland
Otitis media, unspecified
+∞
12.9
12
*
J159, ,
ICD-10 Finland
Bacterial pneumonia, unspecified
+∞
12.9
12
*
J209, ,
ICD-O-3
+∞
12.9
12
*
Z3229, ,
ICD-O-3
+∞
12.9
12
*
S01CA01, ,
ATC
dexamethasone and antiinfectives; ophthalmic
+∞
12.9
12
*
Z315, ,
ICD-10 Finland
Genetic counselling
+∞
12.9
12
*
Z0389, ,
ICD-10 Finland
Observation for other suspected diseases and conditions
+∞
11.8
11
*
Q250, ,
ICD-10 Finland
Patent ductus arteriosus
+∞
11.8
11
*
F790, ,
ICD-O-3
+∞
11.8
11
*
R05FB02, ,
ATC
cough suppressants and expectorants; systemic
+∞
11.8
11
*
LC2BE, ,
ICD-O-3
+∞
11.8
11
*
SPAT1262, ,
ICD-O-3
+∞
11.8
11
*
XF600, ,
ICD-O-3
+∞
11.8
11
*
SAB02, ,
ICD-O-3
+∞
11.8
11
*
M01AE03, ,
ATC
ketoprofen; systemic, rectal
+∞
11.8
11
*
A02BC05, ,
ATC
esomeprazole; systemic
+∞
11.8
11
*
H81, ,
ICD-O-3
+∞
11.8
11
*
J01FA01, ,
ATC
erythromycin; systemic
+∞
11.8
11
*
R05FA02, ,
ATC
opium derivatives and expectorants; systemic
+∞
11.8
11
*
E039, ,
ICD-10 Finland
Hypothyroidism, unspecified
+∞
11.8
11
*
C10AA05, ,
ATC
atorvastatin; oral
+∞
11.8
11
*
OAB43, ,
ICD-O-3
+∞
11.8
11
*
SPAT1316, ,
ICD-O-3
+∞
11.8
11
*
R01BA52, ,
ATC
pseudoephedrine, combinations; oral
+∞
11.8
11
*
Z2446, ,
ICD-O-3
+∞
11.8
11
*
K0366, ,
ICD-O-3
+∞
11.8
11
*
N02AJ06, ,
ATC
codeine and paracetamol; systemic
+∞
11.8
11
*
J040, ,
ICD-10 Finland
Acute laryngitis
+∞
11.8
11
*
M01AC06, ,
ATC
meloxicam; systemic, rectal
+∞
10.7
10
*
J010, ,
ICD-O-3
+∞
10.7
10
*
E039, ,
ICD-O-3
+∞
10.7
10
*
Q2121, ,
ICD-10 Finland
Atrioventricular duct
+∞
10.7
10
*
Z760, ,
ICD-O-3
+∞
10.7
10
*
SPAT1260, ,
ICD-O-3
+∞
10.7
10
*
K0510, ,
ICD-O-3
+∞
10.7
10
*
WX400, ,
ICD-O-3
+∞
10.7
10
*
N05AH04, ,
ATC
quetiapine; oral
+∞
10.7
10
*
K219, ,
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
+∞
10.7
10
*
H903, ,
ICD-10 Finland
Sensorineural hearing loss, bilateral
+∞
10.7
10
*
UJF32, ,
ICD-O-3
+∞
10.7
10
*
ZXA05, ,
ICD-O-3
+∞
10.7
10
*
WX002, ,
ICD-O-3
+∞
10.7
10
*
L309, ,
ICD-O-3
+∞
10.7
10
*
H612, ,
ICD-10 Finland
Impacted cerumen
+∞
10.7
10
*
N06AB04, ,
ATC
citalopram; systemic
+∞
10.7
10
*
Z358, ,
ICD-10 Finland
Supervision of other high-risk pregnancies
+∞
10.7
10
*
N03AG01, ,
ATC
valproic acid; systemic, rectal
+∞
10.7
10
*
H522, ,
ICD-10 Finland
Astigmatism
+∞
10.7
10
*
H100, ,
ICD-O-3
+∞
10.7
10
*
DFF00, ,
ICD-O-3
+∞
10.7
10
*
N02AX02, ,
ATC
tramadol; systemic, rectal
+∞
10.7
10
*
K051, ,
ICD-O-3
+∞
10.7
10
*
H520, ,
ICD-10 Finland
Hypermetropia
+∞
10.7
10
*
DFF20, ,
ICD-O-3
+∞
10.7
10
*
SPAT1223, ,
ICD-O-3
+∞
10.7
10
*
S01GX01, ,
ATC
cromoglicic acid; ophthalmic
+∞
9.6
9
*
SPAT1033, ,
ICD-O-3
+∞
9.6
9
*
J02AC02, ,
ATC
itraconazole; systemic
+∞
9.6
9
*
103, ,
Kela drug reimbursment
Diabetes, insulin-treated
+∞
9.6
9
*
M796, ,
ICD-O-3
+∞
9.6
9
*
Q901, ,
ICD-10 Finland
Trisomy 21, mosaicism (mitotic nondisjunction)
+∞
9.6
9
*
SGA01, ,
ICD-O-3
+∞
9.6
9
*
A09, ,
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
+∞
9.6
9
*
G473, ,
ICD-10 Finland
Sleep apnoea
+∞
9.6
9
*
C07AB07, ,
ATC
bisoprolol; oral
+∞
9.6
9
*
OAA65, ,
ICD-O-3
+∞
9.6
9
*
H13, ,
ICD-O-3
+∞
9.6
9
*
TPH15, ,
ICD-O-3
+∞
9.6
9
*
TPH07, ,
ICD-O-3
+∞
9.6
9
*
Q909, ,
ICD-O-3
+∞
9.6
9
*
F790, ,
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
+∞
9.6
9
*
Z039, ,
ICD-10 Finland
Observation for suspected disease or condition, unspecified
+∞
9.6
9
*
O351, ,
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
+∞
9.6
9
*
R060, ,
ICD-10 Finland
Dyspnoea
+∞
9.6
9
*
L03, ,
ICD-O-3
+∞
9.6
9
*
H01, ,
ICD-O-3
+∞
9.6
9
*
Z718, ,
ICD-10 Finland
Other specified counselling
+∞
9.6
9
*
J01DA08, ,
ATC
[U] cefaclor
+∞
9.6
9
*
J20, ,
ICD-O-3
+∞
9.6
9
*
FM2CE, ,
ICD-O-3
+∞
9.6
9
*
MA2AE, ,
ICD-O-3
+∞
9.6
9
*
L28, ,
ICD-O-3
+∞
9.6
9
*
SDE03, ,
ICD-O-3
+∞
9.6
9
*
SPAT1384, ,
ICD-O-3
+∞
9.6
9
*
Z208, ,
ICD-O-3
+∞
9.6
9
*
R01AD08, ,
ATC
fluticasone; nasal
+∞
8.5
8
*
J189, ,
ICD-O-3
+∞
8.5
8
*
T86, ,
ICD-O-3
+∞
8.5
8
*
MAA00, ,
ICD-O-3
+∞
8.5
8
*
D07AB08, ,
ATC
desonide; topical
+∞
8.5
8
*
WX702, ,
ICD-O-3
+∞
8.5
8
*
H5030, ,
ICD-10 Finland
Intermittent esotropy
+∞
8.5
8
*
M255, ,
ICD-O-3
+∞
8.5
8
*
ZXE20, ,
ICD-O-3
+∞
8.5
8
*
J353, ,
ICD-10 Finland
Hypertrophy of tonsils with hypertrophy of adenoids
+∞
8.5
8
*
K0725, ,
ICD-O-3
+∞
8.5
8
*
Q90, ,
ICD-10 Finland
Down syndrome
+∞
8.5
8
*
H651, ,
ICD-10 Finland
Other acute nonsuppurative otitis media
+∞
8.5
8
*
SAA04, ,
ICD-O-3
+∞
8.5
8
*
SDE04, ,
ICD-O-3
+∞
8.5
8
*
R03CC02, ,
ATC
salbutamol; systemic
+∞
8.5
8
*
GD1PA, ,
ICD-O-3
+∞
8.5
8
*
R55, ,
ICD-10 Finland
Syncope and collapse
+∞
8.5
8
*
Z011, ,
ICD-O-3
+∞
8.5
8
*
R05DA20, ,
ATC
opium alkaloids and derivatives - combinations
+∞
8.5
8
*
GD1QA, ,
ICD-O-3
+∞
8.5
8
*
A06AC01, ,
ATC
ispaghula (psylla seeds); oral
+∞
8.5
8
*
R2110, ,
ICD-O-3
+∞
8.5
8
*
R568, ,
ICD-10 Finland
Other and unspecified convulsions
+∞
8.5
8
*
WX320, ,
ICD-O-3
+∞
8.5
8
*
75930, ,
ICD-8 Finland
Congenital syndromes affecting multiple systems, Down's disease
+∞
8.5
8
*
203, ,
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
+∞
8.5
8
*
R509, ,
ICD-10 Finland
Fever, unspecified
+∞
8.5
8
*
SPAT1389, ,
ICD-O-3
+∞
8.5
8
*
WZC30, ,
ICD-O-3
+∞
8.5
8
*
R101, ,
ICD-O-3
+∞
8.5
8
*
EBA05, ,
ICD-O-3
+∞
8.5
8
*
R53, ,
ICD-O-3
+∞
8.5
8
*
D07XC01, ,
ATC
betamethasone; topical
+∞
8.5
8
*
E0380, ,
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
+∞
8.5
8
*
C08CA01, ,
ATC
amlodipine; oral
+∞
8.5
8
*
MA2HE, ,
ICD-O-3
+∞
8.5
8
*
SPAT1153, ,
ICD-O-3
+∞
8.5
8
*
R4190, ,
ICD-O-3
+∞
8.5
8
*
Q2108, ,
ICD-10 Finland
Other specifed ventricular septal defect
+∞
8.5
8
*
A97, ,
ICD-O-3
+∞
8.5
8
*
C09CA06, ,
ATC
candesartan; oral
+∞
8.5
8
*
S29, ,
ICD-O-3
+∞
8.5
8
*
J2190, ,
ICD-10 Finland
Acute obstructive bronchitis in children
+∞
8.5
8
*
SPAT1156, ,
ICD-O-3
+∞
8.5
8
*
H720, ,
ICD-10 Finland
Central perforation of tympanic membrane
+∞
8.5
8
*
R06AX13, ,
ATC
loratadine; oral
+∞
7.4
7
*
D01AE16, ,
ATC
amorolfine; topical
+∞
7.4
7
*
SPAT1230, ,
ICD-O-3
+∞
7.4
7
*
Z508, ,
ICD-10 Finland
Care involving use of other rehabilitation procedures
+∞
7.4
7
*
E000006, ,
ATC
+∞
7.4
7
*
WYA10, ,
ICD-O-3
+∞
7.4
7
*
N05BA04, ,
ATC
oxazepam; oral
+∞
7.4
7
*
O244, ,
ICD-10 Finland
Diabetes mellitus arising in pregnancy
+∞
7.4
7
*
O021, ,
ICD-10 Finland
Missed abortion
+∞
7.4
7
*
Z712, ,
ICD-O-3
+∞
7.4
7
*
NG1AA, ,
ICD-O-3
+∞
7.4
7
*
N05AX08, ,
ATC
risperidone; systemic
+∞
7.4
7
*
SPAT1385, ,
ICD-O-3
+∞
7.4
7
*
SPAT1303, ,
ICD-O-3
+∞
7.4
7
*
E000001, ,
ATC
+∞
7.4
7
*
N06AX11, ,
ATC
mirtazapine; oral
+∞
7.4
7
*
FM1BE, ,
ICD-O-3
+∞
7.4
7
*
RD210, ,
ICD-O-3
+∞
7.4
7
*
SPAT1016, ,
ICD-O-3
+∞
7.4
7
*
F03, ,
ICD-O-3
+∞
7.4
7
*
Z014, ,
ICD-10 Finland
Gynaecological examination (general)(routine)
+∞
7.4
7
*
EBA15, ,
ICD-O-3
+∞
7.4
7
*
C07AA05, ,
ATC
propranolol; systemic
+∞
7.4
7
*
Z718, ,
ICD-O-3
+∞
7.4
7
*
WX892, ,
ICD-O-3
+∞
7.4
7
*
MCA10, ,
ICD-O-3
+∞
7.4
7
*
K045, ,
ICD-O-3
+∞
7.4
7
*
H10, ,
ICD-O-3
+∞
7.4
7
*
MA2XE, ,
ICD-O-3
+∞
7.4
7
*
N920, ,
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
+∞
7.4
7
*
M545, ,
ICD-O-3
+∞
7.4
7
*
R074, ,
ICD-10 Finland
Chest pain, unspecified
+∞
7.4
7
*
Z349, ,
ICD-10 Finland
Supervision of normal pregnancy, unspecified
+∞
7.4
7
*
K021, ,
ICD-10 Finland
Caries of dentine
+∞
7.4
7
*
K0518, ,
ICD-O-3
+∞
7.4
7
*
R03BA02, ,
ATC
budesonide; inhalant
+∞
7.4
7
*
H103, ,
ICD-O-3
+∞
7.4
7
*
104, ,
Kela drug reimbursment
Thyroid insufficiency
+∞
7.4
7
*
MA2DE, ,
ICD-O-3
+∞
7.4
7
*
UDH02, ,
ICD-O-3
+∞
7.4
7
*
WX722, ,
ICD-O-3
+∞
7.4
7
*
TLC00, ,
ICD-O-3
+∞
7.4
7
*
111, ,
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
+∞
7.4
7
*
K020, ,
ICD-O-3
+∞
7.4
7
*
Z302, ,
ICD-10 Finland
Sterilization
+∞
7.4
7
*
M751, ,
ICD-O-3
+∞
7.4
7
*
D07BA04, ,
ATC
hydrocortisone and antiseptics; topical
+∞
7.4
7
*
4451, ,
ICD-O-3
+∞
6.3
6
*
H521, ,
ICD-10 Finland
Myopia
+∞
6.3
6
*
EMB10, ,
ICD-O-3
+∞
6.3
6
*
SPAT1250, ,
ICD-O-3
+∞
6.3
6
*
C10AA01, ,
ATC
simvastatin; oral
+∞
6.3
6
*
SJB00, ,
ICD-O-3
+∞
6.3
6
*
C09AA05, ,
ATC
ramipril; oral
+∞
6.3
6
*
E000002, ,
ATC
+∞
6.3
6
*
SPAT1216, ,
ICD-O-3
+∞
6.3
6
*
J351, ,
ICD-10 Finland
Hypertrophy of tonsils
+∞
6.3
6
*
K0382, ,
ICD-O-3
+∞
6.3
6
*
KC1EE, ,
ICD-O-3
+∞
6.3
6
*
215, ,
Kela drug reimbursment
Diabetes, non-insulin-treated
+∞
6.3
6
*
C01AA05, ,
ATC
digoxin; systemic
+∞
6.3
6
*
OAB42, ,
ICD-O-3
+∞
6.3
6
*
F71, ,
ICD-O-3
+∞
6.3
6
*
SPAT1382, ,
ICD-O-3
+∞
6.3
6
*
L15, ,
ICD-O-3
+∞
6.3
6
*
Z392, ,
ICD-10 Finland
Routine postpartum follow-up
+∞
6.3
6
*
FXA00, ,
ICD-O-3
+∞
6.3
6
*
L02, ,
ICD-O-3
+∞
6.3
6
*
H500, ,
ICD-10 Finland
Convergent concomitant strabismus
+∞
6.3
6
*
SCA03, ,
ICD-O-3
+∞
6.3
6
*
D07CC01, ,
ATC
betamethasone and antibiotics; topical
+∞
6.3
6
*
R01BA51, ,
ATC
phenylpropanolamine, combinations; oral
+∞
6.3
6
*
N02CC01, ,
ATC
sumatriptan; nasal, systemic, rectal
+∞
6.3
6
*
J01EA01, ,
ATC
trimethoprim; systemic
+∞
6.3
6
*
I10, ,
ICD-O-3
+∞
6.3
6
*
R238, ,
ICD-O-3
+∞
6.3
6
*
SCF02, ,
ICD-O-3
+∞
6.3
6
*
LC2AE, ,
ICD-O-3
+∞
6.3
6
*
E109, ,
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
+∞
6.3
6
*
H900, ,
ICD-10 Finland
Conductive hearing loss, bilateral
+∞
6.3
6
*
Z1388, ,
ICD-O-3
+∞
6.3
6
*
AA1BG, ,
ICD-O-3
+∞
6.3
6
*
F73, ,
ICD-O-3
+∞
6.3
6
*
WX105, ,
ICD-O-3
+∞
6.3
6
*
R13, ,
ICD-10 Finland
Dysphagia
+∞
6.3
6
*
Z015, ,
ICD-10 Finland
Diagnostic skin and sensitization tests
+∞
6.3
6
*
H109, ,
ICD-O-3
+∞
6.3
6
*
FM1DE, ,
ICD-O-3
+∞
6.3
6
*
R104, ,
ICD-O-3
+∞
6.3
6
*
S10, ,
ICD-O-3
+∞
6.3
6
*
C03CA01, ,
ATC
furosemide; systemic
+∞
6.3
6
*
A03FA01, ,
ATC
metoclopramide; systemic, rectal
+∞
6.3
6
*
G473, ,
ICD-O-3
+∞
6.3
6
*
J459, ,
ICD-O-3
+∞
6.3
6
*
N03AX16, ,
ATC
[U] pregabalin
+∞
6.3
6
*
Z301, ,
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
+∞
6.3
6
*
MBA03, ,
ICD-O-3
+∞
6.3
6
*
H652, ,
ICD-10 Finland
Chronic serous otitis media
+∞
6.3
6
*
XMA22, ,
ICD-O-3
+∞
6.3
6
*
DCA10, ,
ICD-O-3
+∞
6.3
6
*
J352, ,
ICD-10 Finland
Hypertrophy of adenoids
+∞
6.3
6
*
Z713, ,
ICD-10 Finland
Dietary counselling and surveillance
+∞
6.3
6
*
Z035, ,
ICD-10 Finland
Observation for other suspected cardiovascular diseases
+∞
6.3
6
*
Z360, ,
ICD-10 Finland
Antenatal screening for chromosomal anomalies
+∞
6.3
6
*
L200, ,
ICD-10 Finland
Besnier prurigo
+∞
6.3
6
*
U071, ,
ICD-O-3
+∞
6.3
6
*
G03DC03, ,
ATC
lynestrenol; oral
+∞
6.3
6
*
S525, ,
ICD-10 Finland
Fracture of lower end of radius
+∞
6.3
6
*
L12, ,
ICD-O-3
+∞
6.3
6
*
M03BC01, ,
ATC
orphenadrine (citrate); systemic
+∞
6.3
6
*
Z017, ,
ICD-O-3
+∞
6.3
6
*
W22, ,
ICD-10 Finland
Striking against or struck by other object(s)
+∞
6.3
6
*
S21, ,
ICD-O-3
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
16
60
3.13
3.50
1.4
1.3
326.50
178.59
iu/ml
—
8
27
25
146
2.08
2.14
8.0
8.9
1.62
1.13
inr
—
5
42
32
211
1.92
1.92
2.0
1.6
13.40
2.65
u/ml
—
6
38
57
459
2.10
1.85
6.9
3.8
14.66
14.50
pmol/l
0.22
51
435
21
122
2.01
1.79
8.9
10.5
5.45
5.01
kpa
2.04
21
116
18
111
1.83
1.27
9.1
10.1
8.79
9.25
kpa
0.79
18
106
6
25
2.52
1.27
1.3
1.8
—
—
—
0
0
0
33
0.00
1.19
0.0
2.0
—
—
—
0
0
5
22
2.36
1.05
1.6
1.1
—
—
—
0
0
66
695
0.48
1.03
19.5
19.4
135.27
133.58
g/l
0.45
66
689
22
292
0.65
0.89
3.3
3.1
161.26
71.85
ug/l
0.59
22
281
21
150
1.56
0.86
1.7
1.8
83.83
95.42
pmol/l
—
7
87
0
24
0.00
0.81
0.0
1.5
—
0.41
—
0
9
17
232
0.65
0.76
2.9
1.9
—
—
—
0
0
9
57
1.66
0.74
3.8
4.5
273.00
359.65
u/l
—
9
57
7
40
1.83
0.74
3.0
5.1
—
—
—
0
0
12
78
1.64
0.71
3.9
2.5
332.58
332.75
nmol/l
0.00
12
73
5
28
1.84
0.67
1.8
1.8
—
—
—
0
0
39
330
1.39
0.65
6.5
12.2
5.91
6.16
mmol/l
0.51
39
300
0
21
0.00
0.61
0.0
2.4
—
—
—
0
0
0
21
0.00
0.61
0.0
1.9
—
—
—
0
0
46
408
1.34
0.53
6.3
12.4
3.64
3.69
e9/l
0.04
41
340
58
617
0.71
0.47
12.5
12.2
26.54
19.05
mg/l
0.73
48
444
15
115
1.38
0.43
3.5
11.1
1.35
1.35
mmol/l
0.01
15
110
0
15
0.00
0.41
0.0
1.1
—
1.86
—
0
7
0
15
0.00
0.41
0.0
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
15.68
—
0
6
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
8
112
0.68
0.41
1.1
1.5
—
—
—
0
0
5
35
1.46
0.40
1.8
1.7
—
—
—
0
0
24
201
1.29
0.39
4.3
8.8
35.73
36.81
g/l
0.72
24
195
56
593
0.76
0.36
3.7
4.0
—
—
—
0
0
56
591
0.77
0.33
15.5
16.9
14.54
14.06
%
0.41
56
585
16
193
0.78
0.31
6.4
3.0
—
—
—
0
0
11
139
0.75
0.30
2.5
3.2
2.12
2.69
mg/l
0.59
11
124
15
125
1.25
0.25
8.3
18.3
25.76
24.09
mmol/l
1.58
15
125
17
197
0.82
0.23
3.4
3.8
—
—
—
0
0
12
98
1.27
0.23
3.1
12.7
23.67
23.21
mmol/l
0.18
12
98
5
41
1.24
0.22
1.2
7.7
4.24
3.02
g/l
—
5
41
0
11
0.00
0.21
0.0
2.3
—
36.00
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
73.09
—
0
11
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
104.00
—
0
10
0
10
0.00
0.21
0.0
2.5
—
24.67
—
0
10
0
14
0.00
0.20
0.0
1.1
—
1.14
—
0
7
0
14
0.00
0.20
0.0
1.7
—
34.86
—
0
14
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
5
68
0.72
0.17
13.0
19.2
102.00
105.03
mmol/l
—
5
68
9
79
1.16
0.16
1.8
1.8
—
—
—
0
0
18
160
1.17
0.16
2.7
3.1
2.34
2.38
mmol/l
0.58
18
149
9
81
1.13
0.16
2.0
1.9
—
—
—
0
0
40
415
0.92
0.08
6.6
8.5
90.72
95.31
ml/min/173m2
0.72
28
312
6
71
0.83
0.08
1.2
1.9
—
—
—
0
0
25
237
1.08
0.07
3.1
3.4
—
—
—
0
0
11
99
1.13
0.07
1.3
1.2
14.20
22.07
iu/ml
—
5
28
11
100
1.12
0.05
2.0
2.0
—
—
—
0
0
15
143
1.06
0.01
2.0
3.9
44.93
52.55
u/l
0.74
15
138
13
128
1.02
0.00
4.0
3.1
—
—
—
0
0
21
213
0.98
0.00
6.6
4.1
30.19
29.64
u/l
0.06
21
207
0
9
0.00
-0.00
0.0
1.0
—
10.64
—
0
9
5
56
0.89
-0.00
1.2
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
0.00
—
0
9
5
52
0.96
-0.00
1.4
7.6
75.20
87.73
%
—
5
52
0
8
0.00
-0.00
0.0
1.3
—
5.67
—
0
8
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
3.92
—
0
9
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.2
—
187.40
—
0
5
0
9
0.00
-0.00
0.0
1.0
—
0.00
—
0
9
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
9.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
0.00
—
0
9
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
40.68
—
0
9
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
7.28
—
0
9
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
0.00
—
0
9
0
9
0.00
-0.00
0.0
1.0
—
41.12
—
0
9
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
1.49
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
6.18
—
0
9
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
4.6
—
32.74
—
0
8
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
5.06
—
0
9
0
5
0.00
-0.00
0.0
5.2
—
22.40
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
783.00
—
0
6
0
5
0.00
-0.00
0.0
6.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
8.16
—
0
7
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
3.00
—
0
9
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_TRISOMY_21_DUE_TO_MEIOTIC_NONDISJUNCTION – Trisomy 21 (Down syndrome) due to meiotic nondisjunction
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).