Cholangitis (primary sclerosing, PSC), with reimbursement 202

K11_CHOLANGI_STRICT

sclerosing cholangitis: A chronic, autoimmune inflammatory liver disorder characterized by narrowing and scarring of the lumen of the bile ducts. It is often seen in patients with ulcerative colitis. Signs and symptoms include jaundice, fatigue, and malabsorption. It may lead to cirrhosis and liver failure.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

  • K11_REIMB_202
33832

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K83.0
  • Hospital discharge: ICD-9 5761
  • Hospital discharge: ICD-8 5750[4-5]
  • Cause of death: ICD-10 K83.0
  • Cause of death: ICD-9 5761
  • Cause of death: ICD-8 5750[4-5]

2 out of 7 registries used, show all original rules.

785

4. Check minimum number of events

None

785

5. Include endpoints

None

785

6. Filter based on genotype QC (FinnGen only)

720

Control definitions (FinnGen only)

Control exclude
K11_IBD_STRICT_PSC
Control conditions
not K11_REIMB_202

Extra metadata

First used in FinnGen datafreeze
DF3
Parent code in ICD-10
K83
Name in latin
Cholangitis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2699 1491 1192
Only index persons 2473 1364 1109
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.03
Only index persons 0.05 0.05 0.04
Median age at first event (years)
Whole population 52.12 57.80 44.91
Only index persons 50.38 56.59 42.74

-FinnGen-

Key figures

All Female Male
Number of individuals 720 398 322
Unadjusted period prevalence (%) 0.14 0.14 0.15
Median age at first event (years) 46.56 50.40 41.81

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
738
Matched controls
7380
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K51.5
ICD-10 Finland
Left sided colitis
51.3
307.7
307
101
A07EC02
ATC
mesalazine; oral, rectal
38.7
307.7
383
200
UJK02
NOMESCO Finland
ERCP
66.0
307.7
262
61
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
19.7
307.7
365
350
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
49.2
307.7
212
60
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
52.2
307.7
205
54
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
340.4
307.7
410
27
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
+∞
307.7
738
*
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
45.1
307.7
386
175
L04AX01
ATC
azathioprine; systemic
38.5
307.7
250
97
K83.0
ICD-10 Finland
Cholangitis
4503599627370496.0
307.7
733
25
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
132.9
307.7
248
28
A05AA02
ATC
ursodeoxycholic acid; oral
913.9
307.7
586
31
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
55.1
307.7
250
68
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
45.8
307.7
276
95
UJF30
NOMESCO Finland
Ileoscopy through colon
20.6
307.7
395
391
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
92.8
307.7
260
43
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
91.1
299.0
158
22
A07EA06
ATC
budesonide; oral, local oral
21.4
249.4
205
130
A07EC01
ATC
sulfasalazine; oral, rectal
26.9
237.6
173
83
K83.1
ICD-10 Finland
Obstruction of bile duct
48.3
231.7
138
35
UJF32
NOMESCO Finland
Coloscopy
10.3
228.9
468
1066
K51.8
ICD-10 Finland
Other ulcerative colitis
36.9
227.0
146
49
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
57.7
219.2
125
26
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
54.5
213.1
123
27
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
56.0
212.7
122
26
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
8.0
177.4
463
1289
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
80.7
171.8
92
13
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.6
150.9
286
565
WX404
NOMESCO Finland
Intravenous generell anesthesy
6.8
148.7
374
974
L04AX03
ATC
methotrexate; systemic
15.3
145.8
137
108
WX402
NOMESCO Finland
General anaesthesia
6.6
145.2
397
1113
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
67.9
143.6
79
13
K76.9
ICD-10 Finland
Liver disease, unspecified
32.7
140.0
92
32
K50.8
ICD-10 Finland
Other Crohn disease
23.8
138.9
103
50
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
37.3
136.4
86
26
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
45.4
135.5
81
20
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
60.4
135.3
76
14
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
6.0
131.6
421
1334
127
Kela drug reimbursment
Transplant complication
23.3
126.1
94
46
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
35.7
120.8
77
24
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
48.2
119.0
70
16
L04AA06
ATC
mycophenolic acid; systemic
22.4
117.6
89
45
UJK12
NOMESCO Finland
Peroral cholangioscopy
1302.6
117.0
111
*
K50.1
ICD-10 Finland
Crohn disease of large intestine
24.8
116.1
84
38
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
9.3
116.1
157
208
J01MA12
ATC
levofloxacin; systemic
5.9
114.8
284
705
P01BA02
ATC
hydroxychloroquine; oral
13.7
114.3
113
96
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
58.3
113.2
64
12
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
46.0
112.6
67
16
TPH04
NOMESCO Finland
Cathetrisation of vein
5.4
111.3
333
971
L04AD02
ATC
tacrolimus; systemic
29.7
111.1
75
28
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
19.4
103.0
83
48
JN3AD
NOMESCO Finland
Abdominal CT examination
5.8
98.2
230
536
K50.9
ICD-10 Finland
Crohn disease, unspecified
18.0
98.2
82
51
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
29.6
96.4
65
24
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
527.7
95.7
93
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
11.6
93.0
102
101
L04AD01
ATC
ciclosporin; systemic
19.4
89.8
72
41
K74.3
ICD-10 Finland
Primary biliary cirrhosis
329.7
87.7
87
*
Z94.4
ICD-10 Finland
Liver transplant status
148.0
87.2
91
7
L88
ICPC
Rheumatoid/seropositive arthritis
40.7
86.6
53
14
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
14.3
85.8
81
63
L01BB02
ATC
mercaptopurine; oral
17.1
85.7
73
47
ZXE00
NOMESCO Finland
One hour or less
4.4
85.6
458
1997
L04AB04
ATC
adalimumab; parenteral
27.3
83.7
58
23
ZX120
NOMESCO Finland
Intravenous
6.4
83.5
160
306
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
12.2
81.3
85
78
P01AB01
ATC
metronidazole; oral, rectal
4.2
79.8
454
2037
JJC00
NOMESCO Finland
Allogenic transplantation of liver
294.4
79.1
79
*
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
27.1
76.4
53
21
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
36.8
71.6
45
13
A07EA02
ATC
hydrocortisone; rectal
12.2
71.2
74
67
J01MA02
ATC
ciprofloxacin; systemic
3.8
70.7
399
1741
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
376.1
69.8
69
*
H02AB06
ATC
prednisolone; systemic
3.9
69.0
471
2316
WX002
NOMESCO Finland
Sedation and analgesia
4.2
68.5
242
764
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
24.4
66.6
48
21
K85.8
ICD-10 Finland
Other acute pancreatitis
28.1
65.8
45
17
ZXD10
NOMESCO Finland
Scheduled procedure
3.6
65.4
404
1844
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.4
65.4
119
214
K51
ICD-10 Finland
Ulcerative colitis
17.6
64.8
54
33
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
147.1
64.0
67
5
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
10.1
63.2
75
82
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
16.0
62.8
55
37
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
8.4
61.9
85
112
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
8.2
61.9
87
118
R50.9
ICD-10 Finland
Fever, unspecified
4.0
61.4
224
717
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
225.2
61.1
62
*
Z2221
NOMESCO Finland
Medical doctor
3.5
61.0
327
1352
H02AB07
ATC
prednisone; oral
4.5
60.8
177
479
K50.0
ICD-10 Finland
Crohn disease of small intestine
13.0
59.7
59
49
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.5
59.4
456
2340
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.9
57.3
145
350
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
15.8
55.8
49
33
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
93.2
54.8
60
7
WVA20
NOMESCO Finland
Medicine administration
8.1
52.6
74
100
H02AB04
ATC
methylprednisolone; systemic
4.1
52.4
176
526
C10AC01
ATC
colestyramine; oral
9.7
51.4
62
69
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
114.0
49.5
53
5
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.8
47.0
173
548
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
13.7
46.3
44
34
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
17.7
44.7
37
22
JKD20
NOMESCO Finland
Anastomosis of bile duct to jejunum
464.5
44.7
44
*
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
4.7
44.0
112
269
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.9
43.3
378
1976
WX302
NOMESCO Finland
Thoracal epidural anesthesy
5.8
42.7
84
161
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
14.1
41.9
39
29
L01BA01
ATC
methotrexate; systemic
64.0
41.8
48
8
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
430.6
41.6
41
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.1
41.4
132
376
N02AX02
ATC
tramadol; systemic, rectal
2.8
39.8
383
2079
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
61.2
39.8
46
8
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.9
39.5
95
217
TK800
NOMESCO Finland
Hemodialysis
9.9
38.4
45
48
H02AB09
ATC
hydrocortisone; systemic
7.4
38.2
57
82
TPH07
NOMESCO Finland
Cathetrisation of artery
3.7
38.1
139
434
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
8.9
37.7
48
57
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
74.0
37.3
42
6
JN4AD
NOMESCO Finland
Body CT examination
3.8
37.3
132
403
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
10.3
36.8
42
43
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
+∞
36.8
35
*
JN4CD
NOMESCO Finland
Very extensive body CT
7.1
36.6
57
86
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
133.3
36.0
38
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.8
35.9
267
1258
R10.1
ICD-10 Finland
Pain localized to upper abdomen
3.0
35.7
207
854
R94.5
ICD-10 Finland
Abnormal results of liver function studies
10.5
35.7
40
40
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
70.3
35.3
40
6
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
5.4
35.3
73
146
M13.9
ICD-10 Finland
Arthritis, unspecified
4.7
34.7
86
201
5761C
ICD-9 Finland
Other disorders of biliary tract, Cholangitis[CHOLANGITIS SCLEROSIVA]
+∞
34.7
33
*
K75.4
ICD-10 Finland
Autoimmune hepatitis
352.7
34.2
34
*
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
48.1
34.1
41
9
UJF92
NOMESCO Finland
Capsular endoscopy
8.0
33.9
47
62
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
4.8
33.6
81
185
JJ5AT, ,
NOMESCO Finland
177.9
33.0
34
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
8.1
32.6
45
59
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
6.7
32.5
53
84
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
5.6
32.1
63
120
K81.0
ICD-10 Finland
Acute cholecystitis
9.3
31.8
39
44
JAH00
NOMESCO Finland
Laparotomy
6.5
31.4
53
87
WX419
NOMESCO Finland
Other general anesthesy
12.4
30.9
31
26
L04AA13
ATC
[U] leflunomide
167.0
30.9
32
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
5.1
30.5
67
141
L04AA01
ATC
[U] ciclosporin
40.0
30.5
38
10
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
43.2
30.2
37
9
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
3.4
30.2
122
404
ZXE40
NOMESCO Finland
More than seven and less than nine hours
6.9
30.1
48
74
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.9
28.5
164
666
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
9.1
28.2
35
40
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
6.8
27.6
44
68
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
55.6
27.4
32
6
JKA20
NOMESCO Finland
Cholecystectomy
7.4
26.5
39
55
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
3.2
26.4
120
425
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.2
26.4
57
118
JJA20
NOMESCO Finland
Open biopsy of liver
75.2
26.0
29
*
A41.8
ICD-10 Finland
Other specified sepsis
8.6
25.4
33
40
XX2RW, ,
NOMESCO Finland
8.6
25.4
33
40
A02BC02
ATC
pantoprazole; systemic
2.4
25.1
531
3811
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
35.9
24.4
31
9
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
6.2
24.1
42
71
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
23.7
24.1
34
15
C03DA01
ATC
spironolactone; oral
3.1
23.9
114
414
A41.9
ICD-10 Finland
Sepsis, unspecified
5.5
23.9
48
93
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
89.8
23.8
26
*
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
8.9
23.8
30
35
R4110
NOMESCO Finland
Physiotherapy
2.3
23.7
249
1333
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
6.0
23.4
42
73
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
23.0
23.2
33
15
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
22.6
210
1064
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.1
22.4
105
377
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
4.4
22.1
57
137
L04AC05
ATC
ustekinumab; parenteral
26.0
21.9
30
12
M05BA04
ATC
alendronic acid; oral
3.7
21.9
72
207
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.4
21.7
192
950
K92.1
ICD-10 Finland
Melaena
4.2
21.6
59
148
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
44.8
21.5
26
6
UJF02
NOMESCO Finland
Peroral enteroscopy
27.4
21.5
29
11
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.0
21.3
47
99
JX1XE
NOMESCO Finland
Other ultrasound examinaton of alimentary organs
+∞
20.9
20
*
M81.9
ICD-10 Finland
Osteoporosis, unspecified
4.6
20.9
51
117
D64.9
ICD-10 Finland
Anaemia, unspecified
3.2
20.9
91
313
JN1CM
NOMESCO Finland
Upper part of abdomen extensive MRI examination with 3 Tesla magnet
215.8
20.7
21
*
M45
ICD-10 Finland
Ankylosing spondylitis
19.0
20.6
31
17
3AC01, ,
NOMESCO Finland
17.9
20.2
31
18
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
28.0
20.2
27
10
R4190
NOMESCO Finland
Nutritional therapy
3.7
20.1
67
194
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
7.8
20.1
28
37
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
59.2
20.0
23
*
WZC00
NOMESCO Finland
Treatment plan or consultation
2.1
19.9
317
1971
C22.1
ICD-10 Finland
Malignant neoplasm: Intrahepatic bile duct carcinoma
47.4
19.3
23
5
K80.8
ICD-10 Finland
Other cholelithiasis
7.4
19.2
28
39
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.8
18.9
60
168
K85
ICD-10 Finland
Acute pancreatitis
7.5
18.8
27
37
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
45.2
18.3
22
5
R74.8
ICD-10 Finland
Abnormal levels of other serum enzymes
4.0
18.2
54
144
JK3NB
NOMESCO Finland
Percutaneous transhepatic cholangiography
53.9
18.0
21
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.4
17.8
142
665
K83
ICD-10 Finland
Other diseases of biliary tract
+∞
17.8
17
*
K83.3
ICD-10 Finland
Fistula of bile duct
97.4
17.6
19
*
ZXD05
NOMESCO Finland
Urgent procedure
2.1
17.6
247
1453
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
7.0
17.5
27
40
WX004
NOMESCO Finland
Patient-controlled sedation
29.6
17.5
23
8
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.1
17.2
77
268
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
3.4
17.1
66
210
1370
FHL
Colonoscopy, whole colon
32.3
17.1
22
7
A07AA11
ATC
rifaximin; oral
32.3
17.1
22
7
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
5.4
16.9
34
66
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
36.0
16.7
21
6
JKD50
NOMESCO Finland
Hepatoportoenterostomy
+∞
16.7
16
*
K73.0
ICD-10 Finland
Chronic persistent hepatitis, not elsewhere classified
92.2
16.6
18
*
L04AB01
ATC
etanercept; parenteral
173.8
16.6
17
*
JK3SB
NOMESCO Finland
Endoscopic retrorade cholangiography
173.8
16.6
17
*
A07EA01
ATC
prednisolone; oral, rectal
23.7
16.5
23
10
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.9
16.3
82
305
D94
ICPC
Chronic enteritis/ulcerative colitis
14.9
15.9
26
18
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
6.5
15.9
26
41
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
61.4
15.8
18
*
3042, ,
Kela drug reimbursment
34.2
15.8
20
6
253, ,
Kela drug reimbursment
34.2
15.8
20
6
N02AA05
ATC
oxycodone; systemic
2.3
15.7
138
672
Q44.29
ICD-10 Finland
Atresia of bile ducts
+∞
15.7
15
*
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
3.0
15.5
72
256
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
6.9
15.4
24
36
WZC30
NOMESCO Finland
Teaching
2.3
15.3
139
686
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.7
15.0
48
135
C03CA01
ATC
furosemide; systemic
2.1
15.0
189
1060
A02BC01
ATC
omeprazole; systemic
2.0
14.6
207
1208
Q44.21
ICD-10 Finland
Atresia of extrahepatic bile ducts
+∞
14.6
14
*
M01CB01
ATC
sodium aurothiomalate; parenteral
+∞
14.6
14
*
JCA32
NOMESCO Finland
Endoscopic injection in oesophagus
81.8
14.6
16
*
ZJX00
NOMESCO Finland
Double balloon technique in gastroenterological endoscopy
81.8
14.6
16
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.6
14.5
90
373
B01AB05
ATC
enoxaparin; parenteral
1.9
14.2
223
1346
Z2446
NOMESCO Finland
Social worker
2.8
14.1
76
293
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
5.6
14.1
27
50
A07AA09
ATC
vancomycin; oral
10.3
14.1
27
27
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
16.1
14.0
22
14
256, ,
Kela drug reimbursment
30.7
13.9
18
6
I85.0
ICD-10 Finland
Oesophageal varices with bleeding
54.4
13.9
16
*
A06AC01
ATC
ispaghula (psylla seeds); oral
2.0
13.8
198
1159
ZXE20
NOMESCO Finland
More than three and less than five hours
2.3
13.7
116
554
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.7
13.6
32
71
JJ3AT
NOMESCO Finland
Cytology of liver with ultrasound guidance
76.6
13.6
15
*
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
16.6
13.5
21
13
1280
FHL
Endoscopic retrograde cholangiography and pancreaticography
142.5
13.5
14
*
C07AG02
ATC
carvedilol; oral
3.3
13.4
52
166
WX892
NOMESCO Finland
Monitored bed care
2.7
13.4
75
295
A11CC03
ATC
alfacalcidol; systemic
4.7
13.4
31
68
Z3226
NOMESCO Finland
Physiotherapist
2.1
13.2
153
827
XW000
NOMESCO Finland
Bone marrow biopsy
4.0
13.2
38
99
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.5
13.2
47
142
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
6.1
13.1
23
39
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.3
12.9
50
160
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
14.4
12.8
21
15
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
4.1
12.8
35
88
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
5.2
12.8
26
51
RD210, ,
NOMESCO Finland
4.9
12.7
28
59
JK3FT
NOMESCO Finland
Exchange of bile duct catheter with radiological guidance
71.1
12.6
14
*
R18
ICD-10 Finland
Ascites
5.4
12.6
25
48
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
3.3
12.5
48
152
JL5AM
NOMESCO Finland
Bile and pancreas ducts simple MRI examination with 3 Tesla magnet
+∞
12.5
12
*
ZX108
NOMESCO Finland
Inhalation
13.5
12.5
21
16
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
12.4
181
1061
E0000UV, ,
ATC
1.8
12.3
320
2237
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
14.6
12.3
20
14
A07DA03
ATC
loperamide; oral
4.2
12.0
32
79
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
11.9
263
1752
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
15.0
11.8
19
13
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
5.4
11.6
23
44
WW500
NOMESCO Finland
Blood transfusion
3.4
11.5
41
124
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.8
11.5
26
56
C23
ICD-10 Finland
Malignant neoplasm of gallbladder
121.8
11.5
12
*
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
121.8
11.5
12
*
SPAT1255
SPAT
Intravenous administration of medicine
2.9
11.4
53
189
4AB02, ,
NOMESCO Finland
35.6
11.3
14
*
B99
ICD-10 Finland
Other and unspecified infectious diseases
4.8
11.3
25
53
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
13.0
11.2
19
15
K72.0
ICD-10 Finland
Acute and subacute hepatic failure
25.5
11.2
15
6
JLC30
NOMESCO Finland
Pancreatoduodenectomy
14.2
11.0
18
13
K81.9
ICD-10 Finland
Cholecystitis, unspecified
14.2
11.0
18
13
L04AB06
ATC
golimumab; parenteral
44.0
10.9
13
*
JN1DM
NOMESCO Finland
Upper part of abdomen very extensive MRI examination with 3 Tesla magnet
44.0
10.9
13
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.4
10.9
80
358
R11
ICD-10 Finland
Nausea and vomiting
2.3
10.9
86
398
Z93.2
ICD-10 Finland
Ileostomy status
18.1
10.8
16
9
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
60.9
10.6
12
*
TJF80
NOMESCO Finland
Ostomy education
9.4
10.6
21
23
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.6
10.6
25
56
M05BA07
ATC
risedronic acid; oral
4.7
10.5
24
52
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.3
10.5
85
397
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
10.5
119
635
WX872
NOMESCO Finland
Intensive care
3.1
10.5
45
153
K83.2
ICD-10 Finland
Perforation of bile duct
111.5
10.4
11
*
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
+∞
10.4
10
*
D97
ICPC
Liver disease NOS
12.3
10.4
18
15
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
9.0
10.3
21
24
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
5.0
10.3
22
45
XX3DW
NOMESCO Finland
Time consuming IT work
2.3
10.3
83
387
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
4.8
10.3
23
49
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.8
10.3
172
1047
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
13.4
10.2
17
13
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.0
10.2
127
702
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
10.1
115
614
J01DB01
ATC
cefalexin; oral
1.9
10.1
607
5232
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
8.6
10.1
21
25
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
10.0
88
425
6611
FHL
Needle biopsy in the operating room
40.6
10.0
12
*
C24.9
ICD-10 Finland
Malignant neoplasm: Biliary tract, unspecified
40.6
10.0
12
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.9
10.0
46
163
Z3231
NOMESCO Finland
Registered nurse
1.8
9.9
207
1343
WX882
NOMESCO Finland
High dependency care
3.5
9.8
34
101
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
20.3
9.8
14
7
4AA12, ,
NOMESCO Finland
20.3
9.8
14
7
JN4BD
NOMESCO Finland
Extensive body CT
2.3
9.8
77
355
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
9.8
318
2322
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
13.6
9.7
16
12
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
55.7
9.7
11
*
B34.9
ICD-10 Finland
Viral infection, unspecified
3.2
9.6
37
118
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
4.7
9.6
22
48
TBW99
NOMESCO Finland
Other minor procedure in endocrine surgery
9.3
9.6
19
21
M06
ICD-10 Finland
Other rheumatoid arthritis
101.3
9.4
10
*
JK3NT
NOMESCO Finland
Percutaneous transhepatic dilatation of bileducts
101.3
9.4
10
*
K74.5
ICD-10 Finland
Biliary cirrhosis, unspecified
101.3
9.4
10
*
UJK52
NOMESCO Finland
Endoscopy of biliary tract in connection with endoscopic retrograde cholangiopancreatography
101.3
9.4
10
*
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
5.2
9.4
19
37
5714X
ICD-9 Finland
Chronic liver disease and cirrhosis, Chronic hepatitis[HEPATITIS CHRONICA ALIA SEU NUD]
+∞
9.4
9
*
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
+∞
9.4
9
*
C24.00
ICD-10 Finland
Hepatic duct
+∞
9.4
9
*
E86
ICD-10 Finland
Volume depletion
4.4
9.4
23
53
L04AG05
ATC
vedolizumab; parenteral
22.0
9.4
13
6
NH3EA
NOMESCO Finland
Feet X-ray examination with load
7.1
9.4
22
32
K86.2
ICD-10 Finland
Cyst of pancreas
8.8
9.3
19
22
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.3
9.3
35
110
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
4.2
9.2
24
58
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.1
9.1
91
462
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
15.8
9.1
14
9
JLW98
NOMESCO Finland
Other transluminal endoscopic operation on pancreas
37.2
9.0
11
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.9
9.0
42
150
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
18.9
9.0
13
7
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
18.9
9.0
13
7
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
24.3
8.9
12
5
B01AB10
ATC
tinzaparin; parenteral
2.2
8.9
82
404
N02BF02
ATC
pregabalin; oral
2.5
8.9
56
234
K29.7
ICD-10 Finland
Gastritis, unspecified
3.4
8.8
32
98
Z94.0
ICD-10 Finland
Kidney transplant status
7.3
8.8
20
28
L29.9
ICD-10 Finland
Pruritus, unspecified
3.6
8.7
29
84
8170/3-C22.0
ICD-O-3
Hepatocellular carcinoma, NOS, of liver
14.2
8.7
14
10
RS220, ,
NOMESCO Finland
6.7
8.7
21
32
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
6.7
8.7
21
32
K83.4
ICD-10 Finland
Spasm of sphincter of Oddi
50.6
8.7
10
*
D99
ICPC
Disease digestive system other
7.8
8.7
19
25
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
8.4
8.6
18
22
JFF10
NOMESCO Finland
Loop enterostomy
11.7
8.6
15
13
TNG10
NOMESCO Finland
Puncture of knee
11.7
8.6
15
13
H26.3
ICD-10 Finland
Drug-induced cataract
16.5
8.6
13
8
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.9
8.5
39
138
K92.0
ICD-10 Finland
Haematemesis
4.0
8.5
24
62
Q44.20
ICD-10 Finland
Atresia of intrahepatic bile ducts
91.1
8.4
9
*
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
91.1
8.4
9
*
JL5BM
NOMESCO Finland
Bile and pancreas ducts MRI examination with 3 Tesla magnet
91.1
8.4
9
*
JJ9AT
NOMESCO Finland
Sampling of liver transplant under radiological guidance
+∞
8.3
8
*
PC2DE
NOMESCO Finland
Ultrasound examination of liver vasculature with Doppler method
+∞
8.3
8
*
JJC60
NOMESCO Finland
Total excision of transplanted liver
+∞
8.3
8
*
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
+∞
8.3
8
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.6
8.3
49
198
L04AB02
ATC
infliximab; parenteral
10.9
8.3
15
14
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.4
8.3
30
92
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.4
8.3
29
87
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
3.0
8.3
37
129
GD1AD
NOMESCO Finland
Thorax CT examination
2.5
8.3
52
217
A06AC51
ATC
ispaghula, combinations; oral
2.8
8.3
40
146
B01AB04
ATC
dalteparin; parenteral
3.0
8.1
35
120
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
6.4
8.1
20
32
JFF13
NOMESCO Finland
Terminal enterostomy
22.3
8.0
11
5
UJF30, ,
SPAT
7.4
8.0
18
25
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.2
7.9
31
100
K85.1
ICD-10 Finland
Biliary acute pancreatitis
13.2
7.9
13
10
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.9
7.9
117
682
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.3
7.7
28
86
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.2
7.6
67
324
L40.5
ICD-10 Finland
Arthropathic psoriasis
12.0
7.6
13
11
L04AA33
ATC
[U] vedolizumab
25.3
7.6
10
*
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
10.2
7.6
14
14
B03BA03
ATC
hydroxocobalamin; parenteral
2.8
7.5
37
137
57505
ICD-8 Finland
Cholecystitis and cholangitis, without mention of calculus, Cholangitis alia sive NUD
80.9
7.4
8
*
L04AA10
ATC
[U] sirolimus
80.9
7.4
8
*
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
80.9
7.4
8
*
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
4.1
7.4
20
50
130
Kela drug reimbursment
Malignant tumour
2.2
7.4
60
281
J05AB11
ATC
valaciclovir; oral
1.8
7.4
108
627
N18.8
ICD-10 Finland
Other chronic renal failure
4.2
7.3
19
46
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
9.5
7.3
14
15
WW200
NOMESCO Finland
Immunization
3.5
7.3
25
74
K73.8
ICD-10 Finland
Other chronic hepatitis, not elsewhere classified
+∞
7.3
7
*
Q44.3
ICD-10 Finland
Congenital stenosis and stricture of bile ducts
+∞
7.3
7
*
K73.89
ICD-10 Finland
Other long-term hepatitis, not classified differently
+∞
7.3
7
*
8140/3-C23.9
ICD-O-3
Adenocarcinoma, NOS, of gallbladder
+∞
7.3
7
*
M07.4
ICD-10 Finland
Arthropathy in Crohn disease [regional enteritis]
+∞
7.3
7
*
5739X
ICD-9 Finland
Other disorders of liver, Unspecified disorder of liver
+∞
7.3
7
*
4AA33, ,
NOMESCO Finland
+∞
7.3
7
*
UJD02
NOMESCO Finland
Gastroscopy
2.7
7.2
38
145
M79.0
ICD-10 Finland
Rheumatism, unspecified
3.3
7.2
27
85
JLB28
NOMESCO Finland
Endoscopic internal drainage of pancreatic duct
30.3
7.2
9
*
JGB50
NOMESCO Finland
Mucosal proctectomy and ileoanal anastomosis
20.2
7.1
10
5
K74.0
ICD-10 Finland
Hepatic fibrosis
20.2
7.1
10
5
UJG02
NOMESCO Finland
Proctoscopy
3.8
7.1
21
56
JFB00
NOMESCO Finland
Partial resection of small intestine
5.7
7.1
19
34
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.5
7.1
58
1125
K72.9
ICD-10 Finland
Hepatic failure, unspecified
12.2
7.1
12
10
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
12.2
7.1
12
10
K90.0
ICD-10 Finland
Coeliac disease
3.2
7.1
28
91
D98
ICPC
Cholecystitis/cholelithiasis
8.9
7.1
14
16
N17.8
ICD-10 Finland
Other acute renal failure
7.1
7.0
16
23
M35.3
ICD-10 Finland
Polymyalgia rheumatica
3.1
7.0
29
97
K56.0
ICD-10 Finland
Paralytic ileus
7.6
6.9
15
20
K86.1
ICD-10 Finland
Other chronic pancreatitis
7.6
6.9
15
20
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
13.9
6.9
11
8
A10AB05
ATC
insulin aspart; parenteral
2.1
6.8
62
304
L04AA05
ATC
[U] tacrolimus
40.4
6.8
8
*
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
40.4
6.8
8
*
K76.89
ICD-10 Finland
Other specified diseases of liver
16.9
6.8
10
6
PAW37
NOMESCO Finland
Biopsy of temporal artery
16.9
6.8
10
6
L04AF03
ATC
upadacitinib; oral
16.9
6.8
10
6
B07.9
ICD-10 Finland
Verruca simplex
2.7
6.7
35
133
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
6.7
401
3267
298, ,
Kela drug reimbursment
22.7
6.7
9
*
3029
Kela drug reimbursment
Upadacitinib
22.7
6.7
9
*
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
6.5
6.7
16
25
M05BX04
ATC
denosumab; parenteral
2.5
6.6
40
164
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.3
6.6
51
234
D13.6
ICD-10 Finland
Benign neoplasm: Pancreas
10.1
6.5
12
12
M13.0
ICD-10 Finland
Polyarthritis, unspecified
10.1
6.5
12
12
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
6.9
6.5
15
22
J04AB02
ATC
rifampicin; systemic
6.3
6.5
16
26
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.3
6.4
46
204
8160/3-C24.9
ICD-O-3
Cholangiocarcinoma of billiary tract, NOS
70.4
6.4
7
*
5714B
ICD-9 Finland
Chronic liver disease and cirrhosis, Chronic hepatitis[HEPATITIS CHRONICA ACTIVA (HBSAG-)]
70.4
6.4
7
*
JL5CM
NOMESCO Finland
Bile and pancreas ducts extensive MRI examination with 3 Tesla magnet
70.4
6.4
7
*
L04AA11
ATC
[U] etanercept
70.4
6.4
7
*
M01CB03
ATC
auranofin; oral
70.4
6.4
7
*
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
14.5
6.4
10
7
XW4AT
NOMESCO Finland
Biopsy of other inner organ with ultrasound guidance
14.5
6.4
10
7
A02BC05
ATC
esomeprazole; systemic
1.5
6.4
271
2052
A06AD11
ATC
lactulose; oral
1.9
6.4
88
501
K80.1
ICD-10 Finland
Calculus of gallbladder with other cholecystitis
3.5
6.3
21
61
K86.8
ICD-10 Finland
Other specified diseases of pancreas
9.4
6.3
12
13
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
3.9
6.3
18
47
5552A
ICD-9 Finland
Regional enteritis, Small intestine with large intestine
+∞
6.3
6
*
K91.8
ICD-10 Finland
Other postprocedural disorders of digestive system, not elsewhere classified
+∞
6.3
6
*
C24.0
ICD-10 Finland
Malignant neoplasm: Extrahepatic bile duct
+∞
6.3
6
*
T86.4
ICD-10 Finland
Liver transplant failure and rejection
+∞
6.3
6
*
C24.02
ICD-10 Finland
Common bile duct
+∞
6.3
6
*
JFG73
NOMESCO Finland
Excision of ileal pelvic pouch
+∞
6.3
6
*
8160/3-C22.1
ICD-O-3
Cholangiocarcinoma of intrahepatic bile duct
26.9
6.2
8
*
JFH10
NOMESCO Finland
Total colectomy and ileostomy
26.9
6.2
8
*
B80
ICPC
Iron deficiency anaemia
3.3
6.2
23
72
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
5.4
6.2
17
32
TQW40
NOMESCO Finland
Remowal of suture of skin
2.2
6.1
51
242
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
6.1
60
304
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
5.6
6.0
16
29
NF1AA
NOMESCO Finland
Hip X-ray examination
2.1
6.0
54
264

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
488
833
15.34
322.35
2.9
1.3
582.20
470.20
titre
0.58
173
151
246
53
69.12
307.65
1.9
1.1
326.56
98.00
titre
—
96
5
246
103
35.33
307.65
8.6
5.0
39.64
2729.16
u/ml
0.59
226
97
362
115
60.82
307.65
3.3
1.5
0.80
0.68
g/l
0.37
329
93
330
205
28.31
307.65
2.7
1.1
—
—
—
0
0
506
598
24.74
307.65
7.5
2.5
0.21
0.22
g/l
2.68
497
563
446
183
60.07
307.65
2.8
1.2
75.58
84.76
titre
0.21
43
21
468
410
29.47
307.65
3.3
1.7
1.34
1.28
g/l
0.23
455
377
494
510
27.27
307.65
4.9
2.6
12.09
10.23
g/l
13.08
480
466
450
234
47.72
307.65
8.7
3.4
59.19
1710.63
u/ml
1.47
421
202
530
560
31.03
307.65
9.0
4.5
2.93
14.92
ug/l
0.92
430
458
213
39
76.37
307.65
2.4
1.3
—
—
—
0
0
452
740
14.18
305.87
13.9
3.0
11.67
8.15
umol/l
1.99
430
654
481
944
12.76
277.11
6.4
2.7
174.99
120.20
ug/g
3.03
463
760
424
718
12.53
275.27
3.5
1.3
—
—
—
0
0
396
621
12.60
272.89
7.3
2.5
40.70
110.35
u/l
0.42
385
516
562
1585
11.67
224.87
19.9
4.4
94.70
92.15
%
1.71
554
1555
697
2601
31.24
212.73
23.6
5.2
35.77
36.44
g/l
2.85
690
2465
646
2271
15.80
204.94
17.8
3.3
39.59
31.90
u/l
3.39
634
2152
665
2616
16.59
181.82
24.0
11.2
1.12
1.18
inr
3.60
612
2151
152
99
19.08
180.43
1.2
1.1
1.56
1.47
g/l
1.55
142
90
384
888
7.93
177.30
3.2
2.0
—
—
—
0
0
499
1502
8.17
176.21
3.3
1.5
2.57
2.25
g/l
4.16
457
914
370
858
7.64
169.17
3.6
2.7
22.10
23.16
%
0.65
360
812
112
53
24.73
152.89
1.2
1.0
—
—
—
0
0
381
999
6.82
150.73
3.8
2.6
12.91
13.80
umol/l
1.29
370
936
365
935
6.75
147.52
3.7
2.6
2.41
2.37
g/l
0.66
356
872
101
46
25.28
139.72
1.2
1.0
—
—
—
0
0
636
2825
10.05
137.74
6.2
2.5
74.84
75.73
nmol/l
0.38
629
2577
645
2968
10.31
132.38
20.4
6.2
9.06
8.76
%
1.72
639
2797
643
2961
10.10
131.47
20.4
6.1
2.97
2.88
%
0.53
636
2782
643
2961
10.10
131.47
20.5
6.2
0.76
0.68
%
3.72
636
2776
515
1970
6.34
128.39
7.1
2.6
68.57
61.75
u/l
0.60
505
1851
663
3209
11.49
126.56
20.3
6.0
0.57
0.57
e9/l
0.10
631
2715
663
3215
11.45
126.10
20.4
6.0
0.04
0.04
e9/l
0.15
631
2724
668
3325
11.64
121.54
20.9
6.4
0.19
0.19
e9/l
0.05
635
2868
662
3298
10.78
119.22
20.6
6.1
1.80
2.00
e9/l
3.81
631
2881
83
34
27.38
119.14
51.1
33.6
6.50
7.24
ug/l
1.17
76
28
473
1779
5.62
117.24
7.0
4.2
7.39
7.40
ph
0.84
369
1240
248
557
6.20
111.55
16.9
8.9
7.81
8.12
mmol/l
0.31
241
537
618
3007
7.49
110.04
15.9
8.1
1.21
1.21
mmol/l
0.04
565
2625
308
853
5.48
109.15
1.8
1.7
—
—
—
0
0
676
3587
11.53
109.07
24.9
9.6
3.78
4.00
e9/l
2.06
648
3094
68
21
35.57
106.79
5.0
2.2
0.59
0.60
mmol/l
0.23
68
21
487
1989
5.26
105.78
4.8
2.5
—
—
—
0
0
578
2736
6.13
103.66
14.3
7.7
1.22
1.22
mmol/l
0.03
565
2542
125
144
10.25
102.55
6.4
3.2
33.87
34.30
umol/l
0.07
118
131
138
187
8.85
99.57
1.6
1.5
364.56
237.59
u/ml
1.90
81
99
133
179
8.84
96.39
1.8
1.6
—
—
—
0
0
409
1549
4.68
95.38
4.8
2.3
2.92
2.86
mg/l
0.19
381
1336
127
166
9.03
94.19
1.7
1.6
157.81
142.74
au/ml
0.51
31
61
98
92
12.13
92.55
7.2
2.5
28.15
7.34
umol/l
4.39
90
67
338
1132
4.66
92.12
1.9
1.7
—
—
—
0
0
407
1571
4.55
91.65
9.4
4.3
—
—
—
0
0
63
26
26.40
89.77
1.6
3.1
—
—
—
0
0
211
512
5.37
85.01
1.8
1.5
—
—
—
0
0
640
3602
6.85
85.00
14.5
5.7
6.30
6.58
mmol/l
3.24
629
3402
80
68
13.07
80.26
2.0
1.4
—
—
—
0
0
80
69
12.88
79.52
2.1
1.3
8.73
6.41
g/l
2.97
47
52
80
69
12.88
79.52
2.1
1.3
0.43
0.35
g/l
0.60
46
52
80
69
12.88
79.52
2.1
1.3
3.49
2.74
g/l
1.58
46
52
552
2851
4.71
79.32
31.4
10.7
0.00
0.00
e9/l
0.46
500
2289
101
125
9.20
77.82
1.2
1.1
—
—
—
0
0
703
4532
12.62
73.92
14.6
3.6
16.78
10.54
mm/h
19.80
693
4229
365
1485
3.88
72.25
4.5
2.5
—
—
—
0
0
51
24
22.75
68.82
1.0
1.2
—
—
—
0
0
51
24
22.75
68.82
1.0
1.0
—
—
—
0
0
531
2832
4.12
68.74
5.3
2.8
—
—
estimate
—
0
0
150
323
5.57
68.25
1.6
1.5
—
—
—
0
0
45
17
28.12
65.84
3.6
3.9
58.38
5.99
ug/l
0.48
45
17
89
117
8.51
65.04
1.1
1.1
—
—
—
0
0
689
4570
8.65
64.14
19.3
3.3
122.66
44.82
u/l
28.94
682
4361
248
843
3.92
62.53
12.2
7.3
1.09
1.08
mmol/l
0.13
242
788
245
826
3.94
62.51
13.4
8.4
104.84
104.25
mmol/l
0.97
245
826
472
2433
3.61
61.91
3.4
2.0
—
—
—
0
0
62
55
12.21
60.27
1.1
1.1
309.74
286.85
mg/l
0.94
53
47
404
1917
3.45
60.06
13.3
6.4
—
—
—
0
0
71
80
9.71
58.46
1.2
1.3
—
—
—
0
0
536
3095
3.67
56.54
5.6
3.1
107.40
112.61
ug/l
0.25
521
2913
276
1071
3.52
56.08
7.9
4.4
0.79
0.82
mmol/l
5.04
271
1022
40
17
24.82
55.97
1.1
1.1
—
—
—
0
0
71
85
9.14
55.77
2.5
2.6
17.71
24.76
iu/ml
—
9
7
171
480
4.34
55.67
7.0
4.9
0.49
0.66
%
0.56
76
157
176
505
4.26
55.64
7.4
5.0
0.66
0.98
%
1.16
82
169
241
864
3.66
55.28
1.6
1.2
—
—
—
0
0
169
489
4.19
52.61
7.7
5.5
0.01
0.20
%
1.45
68
127
181
556
3.99
51.80
1.4
1.6
—
—
—
0
0
93
166
6.27
51.11
1.3
1.3
—
—
—
0
0
200
665
3.75
50.94
4.5
3.8
1.93
1.80
%
0.74
190
610
163
475
4.12
50.08
7.7
5.1
0.03
0.14
%
1.85
69
139
110
237
5.28
49.34
2.2
2.2
1.27
1.46
g/l
1.13
98
213
163
503
3.88
45.93
3.5
3.6
71.24
73.26
e9/l
0.29
116
371
349
1718
2.96
45.23
5.3
3.2
0.28
0.45
e6/l
1.36
282
1240
383
1991
2.92
44.71
5.4
3.3
120.61
80.84
e6/l
0.15
318
1506
416
2272
2.90
44.05
6.7
3.9
19.76
97.13
e6/l
3.17
328
1590
268
1173
3.02
42.55
3.8
2.8
543.49
532.73
mosm/kgh2o
0.35
247
1021
287
1334
2.88
40.44
4.1
2.6
7.36
5.98
e6/l
0.37
269
1208
236
1008
2.97
38.59
4.2
3.1
2.80
2.45
e6/l
0.18
138
478
57
84
7.27
37.40
5.1
3.0
4.04
4.29
e9/l
0.27
57
84
41
40
10.79
37.19
7.2
1.4
1.40
1.99
umol/l
2.63
41
35
63
105
6.47
36.83
1.0
1.1
—
—
—
0
0
169
610
3.30
36.81
19.8
10.9
—
—
—
0
0
181
695
3.13
35.40
11.3
5.3
7.37
7.38
ph
2.46
111
400
175
662
3.15
35.09
11.1
5.4
0.86
1.66
mmol/l
1.83
157
574
239
1079
2.80
34.72
4.1
2.9
0.78
1.10
e6/l
0.93
144
547
171
642
3.17
34.70
3.1
2.1
329.59
373.37
nmol/l
2.25
165
605
178
688
3.09
34.33
11.1
5.2
5.71
5.78
kpa
0.47
173
674
293
1475
2.64
34.18
4.7
2.9
337.11
340.31
umol/l
0.20
279
1320
117
356
3.72
33.05
1.6
1.7
0.17
0.31
mg/l
2.23
28
176
86
214
4.42
32.01
1.7
1.4
13.50
6.23
iu/ml
0.31
15
47
127
417
3.47
31.91
5.9
4.2
1.23
1.23
mmol/l
0.22
120
360
187
783
2.86
30.91
1.4
1.3
—
—
—
0
0
281
1446
2.52
30.64
10.9
4.6
—
—
—
0
0
97
274
3.92
30.41
6.1
3.3
21.35
21.30
s
0.04
92
252
64
131
5.25
30.09
4.8
2.8
55.98
56.84
%
0.16
64
131
180
751
2.85
29.85
4.7
3.1
3.63
5.19
e9/l
1.40
165
666
574
4155
2.72
28.59
7.2
4.1
—
2.70
—
0
8
275
1439
2.45
28.52
2.1
2.1
—
—
—
0
0
555
3968
2.61
28.09
6.2
4.3
1463.00
1318.60
e6/l
—
5
62
412
2621
2.29
26.63
2.7
2.0
93.98
97.23
pmol/l
0.72
247
1360
485
3307
2.36
26.54
5.2
3.5
0.00
0.50
estimate
0.50
124
612
482
3284
2.35
26.33
5.2
3.5
10.74
5.32
estimate
0.20
129
658
479
3260
2.34
26.15
5.2
3.5
0.00
0.00
estimate
0.50
128
650
103
356
3.20
23.52
1.5
1.2
—
—
—
0
0
669
5452
3.43
23.01
59.8
17.4
14.00
13.45
%
18.56
669
5396
405
2662
2.16
22.85
4.3
3.2
6.14
6.19
ph
0.42
206
1559
726
6284
10.55
22.48
57.2
13.8
18.88
22.85
mg/l
4.78
710
4990
146
627
2.66
22.36
15.7
10.9
0.00
0.90
mmol/l
1.68
124
532
147
634
2.65
22.32
15.8
10.9
7.40
7.42
ph
0.64
65
348
293
1711
2.18
22.28
1.6
1.4
1.08
1.63
u/ml
0.79
73
464
111
418
2.95
21.79
2.1
3.2
67.14
66.75
g/l
0.17
106
390
69
199
3.72
20.83
1.6
1.5
228.45
290.04
ug/g
1.34
47
123
28
37
7.83
20.07
1.1
1.1
1412.00
1558.73
miu/ml
0.32
28
37
177
873
2.35
19.95
2.0
1.7
1205.46
1170.77
nmol/l
0.18
148
660
96
353
2.98
19.59
19.9
13.0
23.72
24.30
mmol/l
0.91
96
347
69
209
3.54
19.35
2.1
1.7
1.89
1.44
ug/l
0.27
63
188
301
1886
2.01
18.05
1.7
1.5
—
—
—
0
0
275
1669
2.03
18.04
2.3
1.6
19.08
20.66
nmol/l
1.11
259
1426
108
444
2.68
17.83
9.6
4.9
95.38
80.29
ng/l
0.73
102
401
90
338
2.89
17.63
2.2
2.6
—
—
—
0
0
160
803
2.27
17.07
2.0
1.4
—
—
—
0
0
82
298
2.97
17.03
3.0
1.2
0.86
0.91
g/l
1.16
82
298
96
381
2.75
16.94
20.1
12.9
1.27
1.37
%
0.78
96
381
57
166
3.64
16.94
3.9
3.0
3.36
2.34
index
0.62
32
94
316
2069
1.92
16.22
4.7
3.4
2.33
2.36
mmol/l
2.70
297
1895
21
7
30.82
16.18
3.6
2.6
3.03
3.36
mg/l
—
21
7
272
1702
1.95
15.92
3.4
2.9
—
—
—
0
0
240
1439
1.99
15.91
3.7
2.0
1.76
1.24
mg/l
1.03
197
1116
42
105
4.18
15.43
3.7
3.6
2.06
2.73
mmol/l
0.79
29
72
53
164
3.40
14.36
1.4
1.2
6.90
3.35
u/ml
—
6
22
105
480
2.38
13.74
4.7
3.3
—
—
—
0
0
199
1176
1.95
13.41
2.0
1.7
436.28
15669097.58
pmol/l
0.69
178
1002
22
17
13.30
12.98
2.4
1.4
—
—
—
0
0
246
1585
1.83
12.55
3.2
3.5
1190.90
947.23
ng/l
0.61
209
1339
28
60
4.81
12.45
1.3
1.1
—
—
—
0
0
21
17
12.68
12.18
2.3
1.4
10500.40
8070.88
e6/l
—
10
8
42
127
3.45
11.80
5.1
3.3
—
—
—
0
0
28
63
4.58
11.75
3.2
4.1
—
—
—
0
0
21
19
11.34
11.59
1.6
1.2
31.03
36.36
%
0.17
11
11
22
23
9.82
11.30
2.2
1.5
769.93
1205.56
e6/l
0.31
14
18
716
6554
4.10
11.26
38.0
12.2
—
—
—
0
0
21
38
5.66
11.22
1.2
1.0
—
—
—
0
0
116
599
2.11
11.22
11.6
5.0
5.06
4.69
kpa
0.95
111
585
20
18
11.39
11.09
2.4
1.3
—
—
—
0
0
135
744
2.00
10.93
2.0
1.6
—
—
—
0
0
22
44
5.12
10.57
4.5
2.6
1.77
0.95
index
0.87
22
44
36
107
3.49
10.40
2.5
1.5
6854.24
20575.16
e6/l
1.33
21
74
23
31
7.62
10.24
1.6
1.3
74.50
60.00
%
—
10
23
44
150
3.06
10.20
7.2
9.6
1.17
1.30
mmol/l
0.56
39
131
256
1760
1.70
9.96
5.5
3.5
0.01
0.01
estimate
0.00
124
615
32
95
3.48
9.27
2.0
1.6
—
—
—
0
0
32
95
3.48
9.27
2.0
1.6
—
—
—
0
0
32
95
3.48
9.27
2.0
1.6
—
—
—
0
0
32
95
3.48
9.27
2.0
1.6
—
—
—
0
0
684
6200
2.41
9.26
7.4
4.9
4.54
4.68
mmol/l
3.45
669
5856
54
220
2.57
9.01
4.2
4.3
132.83
257.50
mg/l
2.45
36
109
53
214
2.59
9.00
7.5
7.3
0.85
0.88
%
0.20
53
203
45
167
2.80
8.99
2.7
4.1
45.13
76.65
mg/l
0.42
34
143
333
2514
1.59
8.60
4.9
3.3
0.01
0.02
estimate
0.32
116
530
44
167
2.74
8.44
2.7
4.1
35.13
29.04
mg/l
0.71
33
142
176
1136
1.72
8.43
3.5
2.8
2.48
2.45
mmol/l
2.64
164
1018
30
91
3.39
8.42
1.5
1.5
18.83
27.84
ng/l
1.15
30
91
259
1854
1.61
8.29
4.2
2.8
0.00
0.06
estimate
0.60
110
510
301
2238
1.58
8.19
4.9
3.5
32.27
75.33
ng/l
0.74
214
1485
18
38
4.83
8.15
2.4
3.4
1271.22
755.24
u/ml
0.77
18
38
55
239
2.41
8.02
7.5
6.8
1.60
1.56
%
0.06
55
228
94
507
1.98
8.00
6.9
4.2
7.39
7.35
ph
2.76
86
365
176
1154
1.69
7.91
4.3
3.9
67.05
418.91
ng/l
4.06
133
826
32
107
3.08
7.70
1.5
1.6
—
—
—
0
0
15
17
8.98
7.57
2.2
1.6
—
—
—
0
0
39
151
2.67
7.23
2.7
4.0
1.34
2.32
ratio
1.18
19
81
90
502
1.90
6.93
12.3
4.9
7.41
7.41
ph
0.39
81
419
31
110
2.90
6.76
4.9
3.7
8.60
8.19
pmol/l
0.07
31
110
155
1025
1.65
6.64
1.4
1.3
14.22
2.02
u/ml
1.28
56
385
29
101
2.95
6.54
9.0
11.7
11.62
11.29
mmol/l
0.23
29
92
29
101
2.95
6.54
9.0
11.7
107.59
105.37
mmol/l
1.85
29
92
52
242
2.24
6.51
1.1
1.1
—
—
—
0
0
25
80
3.20
6.49
2.2
1.4
—
—
—
0
0
18
35
5.24
6.35
1.2
1.0
—
—
—
0
0
13
16
8.25
6.35
5.6
6.3
54.65
46.97
%
0.42
13
16
340
2704
1.48
6.26
2.4
1.9
1.29
1.41
mmol/l
1.90
316
2331
31
116
2.75
6.16
1.6
1.5
48.35
68.90
mmol/l
1.71
20
101
55
272
2.10
5.94
1.3
1.3
—
—
—
0
0
46
212
2.25
5.91
1.4
1.1
—
—
—
0
0
25
86
2.97
5.78
1.4
2.2
—
—
—
0
0
53
262
2.10
5.74
1.3
1.3
283.54
223.00
miu/ml
0.49
19
123
642
5881
1.70
5.61
5.5
4.1
1.19
1.31
mmol/l
5.42
619
5494
21
68
3.15
5.38
2.0
1.8
31.29
32.56
pg
0.69
21
68
17
48
3.60
5.35
1.1
1.1
87.76
113.54
pmol/l
1.44
17
48
41
190
2.23
5.22
1.1
1.1
—
—
—
0
0
20
64
3.18
5.22
1.2
1.1
—
—
—
0
0
673
6271
1.83
5.22
6.8
5.5
2.59
2.77
mmol/l
7.30
652
5896
21
70
3.06
5.13
1.3
1.2
—
—
—
0
0
161
1141
1.53
5.03
1.4
1.3
50.52
21.88
iu/ml
1.29
61
316
88
539
1.72
4.99
3.0
2.0
0.00
0.03
estimate
0.50
20
114
8
8
10.09
4.53
1.1
1.3
—
—
—
0
0
53
290
1.89
4.37
3.3
2.1
0.00
0.04
estimate
0.68
15
99
660
6183
1.64
4.14
6.5
4.8
1.52
1.44
mmol/l
4.25
642
5805
246
1956
1.39
4.08
4.2
3.3
—
0.86
—
0
7
12
26
4.67
4.07
1.2
1.1
—
—
—
0
0
230
1813
1.39
4.01
2.5
2.2
164.82
239.79
u/l
0.61
225
1735
16
53
3.06
3.98
1.6
1.2
—
—
—
0
0
58
341
1.76
3.82
9.7
4.3
0.68
0.61
%
0.94
58
341
89
589
1.58
3.75
1.2
1.2
—
—
—
0
0
17
63
2.74
3.51
1.9
3.2
39.64
37.32
%
0.25
17
63
18
70
2.61
3.40
2.5
2.4
—
—
—
0
0
22
96
2.33
3.29
2.1
1.8
—
—
—
0
0
263
2171
1.33
3.29
4.2
3.5
7.35
8.11
mmol/l
1.78
243
1873
60
373
1.66
3.27
13.9
5.3
—
—
—
0
0
10
24
4.21
3.20
3.2
2.4
—
—
—
0
0
7
13
5.42
2.87
5.0
3.0
173.14
5906.38
u/l
—
7
13
6
9
6.71
2.87
3.2
1.2
—
—
—
0
0
31
165
1.92
2.85
1.2
1.1
—
—
—
0
0
10
28
3.61
2.79
1.2
1.2
—
—
—
0
0
6
10
6.04
2.70
1.0
1.1
—
—
—
0
0
10
29
3.48
2.70
1.0
1.0
—
—
—
0
0
9
24
3.78
2.68
2.2
1.9
118.67
95.65
ug/l
—
9
24
41
658
0.60
2.62
1.5
1.7
3.10
3.50
mmol/l
1.17
30
456
30
164
1.86
2.57
1.2
1.1
—
—
—
0
0
625
5910
1.38
2.52
5.2
4.8
5.85
5.87
mmol/l
0.12
594
5491
16
69
2.35
2.50
1.0
1.1
—
—
—
0
0
10
32
3.15
2.44
2.3
1.2
—
—
—
0
0
8
22
3.66
2.37
1.0
1.0
—
—
—
0
0
8
22
3.66
2.37
1.0
1.0
—
—
—
0
0
8
22
3.66
2.37
1.0
1.0
—
—
—
0
0
12
46
2.64
2.37
1.3
1.3
1089.71
2437.33
e6/l
—
7
27
231
2701
0.79
2.31
4.2
3.0
—
—
—
0
0
13
53
2.48
2.28
2.8
2.5
4.04
3.95
mmol/l
0.28
13
53
8
23
3.50
2.27
2.5
1.8
—
—
—
0
0
7
18
3.92
2.25
2.7
1.7
—
—
—
0
0
11
41
2.71
2.21
1.2
1.3
—
—
—
0
0
21
383
0.54
2.16
1.1
1.1
—
—
—
0
0
94
706
1.38
2.15
1.6
1.5
—
—
—
0
0
7
20
3.52
2.06
1.1
2.0
—
—
—
0
0
16
77
2.10
1.98
1.4
1.3
—
—
—
0
0
614
5845
1.30
1.93
5.7
5.3
1.95
1.88
mu/l
0.69
583
5469
60
425
1.45
1.92
2.7
2.4
21.63
15.50
au/ml
0.25
11
40
7
22
3.20
1.88
1.3
1.9
—
—
—
0
0
6
17
3.55
1.84
1.5
1.8
44.67
30.18
%
—
6
17
12
53
2.29
1.81
3.0
2.5
1.23
1.19
mmol/l
1.34
12
53
12
53
2.29
1.81
3.0
2.5
105.67
105.30
mmol/l
0.10
12
53
50
706
0.69
1.81
1.6
1.7
—
—
—
0
0
12
54
2.24
1.74
1.1
1.1
—
—
—
0
0
217
1873
1.22
1.71
4.1
3.5
43.65
51.19
mg/l
0.20
145
1237
22
128
1.74
1.62
2.4
2.7
46.97
107.49
ug/min
—
9
86
220
1912
1.21
1.62
4.9
4.2
10.55
9.45
mg/mmol
0.08
147
1222
10
209
0.47
1.60
1.2
2.8
—
—
—
0
0
528
4977
1.21
1.59
4.8
4.3
14.70
14.67
pmol/l
0.10
495
4605
6
20
3.02
1.58
1.0
1.1
—
—
—
0
0
20
114
1.78
1.58
1.3
1.1
5.55
2.80
eliau/ml
—
6
52
5
15
3.35
1.52
1.4
1.8
—
—
—
0
0
62
464
1.37
1.50
3.3
2.2
6.13
6.16
ph
0.08
45
300
31
204
1.54
1.45
1.8
1.7
—
—
—
0
0
77
973
0.77
1.41
3.1
2.9
0.89
0.72
ug/l
0.38
45
546
10
46
2.19
1.40
1.5
1.7
—
—
—
0
0
10
47
2.14
1.34
1.5
1.5
—
—
—
0
0
6
24
2.51
1.30
1.7
1.3
26.17
27.00
s
—
6
24
8
35
2.30
1.27
1.0
1.2
—
—
—
0
0
15
86
1.76
1.19
1.3
1.4
269.40
280.43
mosm/kgh2o
—
10
65
5
20
2.51
1.15
1.6
1.2
—
—
—
0
0
7
30
2.35
1.12
2.3
2.0
—
—
—
0
0
11
58
1.91
1.12
1.5
1.2
—
—
—
0
0
60
756
0.78
1.10
1.3
1.4
—
—
—
0
0
14
81
1.74
1.09
1.1
2.1
—
—
—
0
0
5
21
2.39
1.09
1.0
1.2
—
—
—
0
0
5
21
2.39
1.09
1.0
1.2
67.20
72.33
nmol/24h
—
5
21
9
48
1.89
1.00
1.8
2.9
—
—
—
0
0
169
1495
1.17
1.00
5.4
3.5
1.02
1.02
kg/l
0.11
124
988
19
123
1.56
1.00
1.2
1.2
—
—
—
0
0
0
29
0.00
0.98
0.0
1.6
—
0.49
—
0
29
0
30
0.00
0.97
0.0
1.2
—
91.42
—
0
22
9
51
1.77
0.94
1.8
1.5
3.12
3.17
mg/l
—
9
51
6
28
2.15
0.91
1.2
1.5
168.67
178.06
mmol/24h
—
6
28
7
128
0.54
0.89
1.0
1.5
—
—
—
0
0
35
264
1.34
0.87
1.5
1.6
8.44
8.21
u/l
0.02
29
204
62
506
1.25
0.87
1.1
1.3
166.32
148.96
u/ml
0.08
18
214
6
30
2.01
0.87
1.7
1.6
—
—
—
0
0
19
129
1.49
0.84
5.1
4.4
—
—
—
0
0
36
275
1.32
0.84
2.4
2.3
—
—
—
0
0
12
73
1.65
0.82
2.3
2.9
—
—
—
0
0
34
261
1.32
0.77
2.2
2.5
76.82
5709.47
u/l
2.29
11
110
33
253
1.32
0.76
2.0
1.8
—
—
—
0
0
0
28
0.00
0.76
0.0
1.3
—
1.81
—
0
28
12
75
1.61
0.75
3.1
2.7
—
—
—
0
0
21
150
1.41
0.74
1.1
2.1
—
—
—
0
0
28
366
0.76
0.72
1.2
2.1
—
—
—
0
0
9
56
1.61
0.72
1.2
1.2
—
—
—
0
0
600
5845
1.14
0.71
7.5
5.9
37.99
38.72
mmol/mol
1.07
579
5546
5
26
1.93
0.70
4.8
4.8
15.58
16.47
%
—
5
26
24
183
1.32
0.60
1.2
2.1
2.15
4.76
iu/l
—
6
70
0
22
0.00
0.59
0.0
1.7
—
16.60
—
0
22
47
393
1.21
0.57
1.3
1.5
29.66
23.05
iu/l
0.51
38
328
6
39
1.54
0.53
4.2
3.7
6.68
8.22
mmol/l
—
6
39
9
64
1.41
0.51
1.2
1.1
1.13
1.45
nmol/l
—
9
56
9
65
1.39
0.50
3.2
2.2
12.56
10.95
mmol/l
—
9
65
14
188
0.74
0.47
1.7
1.5
59.33
59.13
ug/l
0.01
14
158
13
94
1.39
0.46
1.1
1.2
—
—
—
0
0
11
152
0.72
0.44
1.1
1.2
—
—
—
0
0
39
457
0.85
0.43
1.2
2.2
—
—
—
0
0
39
456
0.85
0.43
1.3
2.0
—
—
—
0
0
105
961
1.11
0.41
1.7
1.6
—
—
—
0
0
8
58
1.38
0.41
1.6
1.7
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
0.69
—
0
9
40
459
0.86
0.36
1.3
2.2
—
—
—
0
0
40
459
0.86
0.36
1.3
2.2
—
—
—
0
0
151
1607
0.92
0.36
4.5
4.7
1.67
1.97
ug/l
0.67
139
1471
20
163
1.23
0.34
1.3
2.0
3.11
10.81
e6/l
—
9
117
20
164
1.23
0.33
1.3
2.1
36.79
193.66
e6/l
1.50
14
121
18
146
1.24
0.32
3.3
4.5
4.11
3.84
mmol/l
0.59
18
146
21
174
1.21
0.31
1.2
1.1
—
—
—
0
0
22
184
1.20
0.30
1.3
2.0
397.86
472.83
mg/l
0.87
22
175
38
430
0.88
0.30
1.2
2.2
—
—
—
0
0
56
507
1.11
0.29
1.6
1.3
139.10
234.41
u/ml
0.80
51
473
50
451
1.12
0.28
2.1
2.3
1.81
8.06
ug/l
8.70
39
409
11
85
1.30
0.28
1.1
1.2
—
—
—
0
0
8
62
1.29
0.28
3.0
3.7
111.13
65.86
u/ml
—
8
62
20
168
1.20
0.27
1.3
1.9
3.61
3.66
mmol/l
0.13
20
159
11
139
0.79
0.27
1.6
1.5
1.30
1.28
mm
0.05
11
103
9
73
1.24
0.25
1.1
1.4
—
—
nmol/l
—
0
0
5
39
1.28
0.23
1.2
1.1
22.40
9.21
mm/h
—
5
39
12
146
0.82
0.22
1.7
1.6
—
—
—
0
0
73
781
0.93
0.22
2.1
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
0.02
—
0
11
0
11
0.00
0.21
0.0
1.1
—
1.19
—
0
6
0
10
0.00
0.21
0.0
1.0
—
9.08
—
0
10
29
259
1.12
0.20
1.7
1.6
40.36
6.75
u/ml
—
7
60
48
443
1.09
0.19
1.1
1.2
—
—
—
0
0
6
53
1.13
0.18
1.0
1.1
—
1.15
—
0
6
26
290
0.89
0.18
1.2
1.1
1.59
1.52
g/l
0.62
26
290
61
650
0.93
0.17
2.2
2.4
16.34
13.76
nmol/l
1.36
55
609
10
82
1.22
0.17
1.0
1.0
—
—
—
0
0
8
69
1.16
0.16
1.0
1.2
—
—
—
0
0
12
141
0.85
0.16
1.6
1.5
—
—
—
0
0
10
86
1.17
0.11
1.4
2.9
—
—
—
0
0
34
321
1.06
0.09
1.2
2.9
—
—
—
0
0
5
60
0.83
0.08
3.6
2.5
—
—
—
0
0
20
185
1.08
0.08
2.7
2.5
—
—
—
0
0
20
187
1.07
0.06
1.2
1.2
7.03
2.74
u/ml
0.37
11
111
17
160
1.06
0.04
1.2
1.1
0.41
1.06
u/ml
—
7
84
17
180
0.94
0.04
8.4
8.8
—
—
—
0
0
13
124
1.05
0.00
1.1
1.1
13.90
8.89
u/ml
—
6
62
16
166
0.96
0.00
1.1
1.1
2.65
1.79
u/ml
—
10
100
16
164
0.98
0.00
1.4
1.3
—
—
—
0
0
36
365
0.99
0.00
1.9
1.7
—
—
—
0
0
14
137
1.02
0.00
1.1
1.1
2.46
4.82
u/ml
—
7
78
28
278
1.01
0.00
2.3
1.9
54.86
37.17
nmol/l
1.91
28
266
11
111
0.99
0.00
1.4
1.2
—
—
—
0
0
17
169
1.01
0.00
1.2
1.1
5.09
4.88
u/ml
—
8
109
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
92.48
—
0
5
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
19.25
—
0
5
0
8
0.00
-0.00
0.0
4.9
—
100.88
—
0
8
0
9
0.00
-0.00
0.0
1.3
—
1.99
—
0
9
0
7
0.00
-0.00
0.0
8.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
38.67
—
0
6
0
5
0.00
-0.00
0.0
1.8
—
288.20
—
0
5
6
60
1.00
-0.00
1.5
1.5
141.28
188.10
pmol/l
—
6
60
0
6
0.00
-0.00
0.0
1.0
—
0.03
—
0
6
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
548.44
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
91.25
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_CHOLANGI_STRICT and mortality.

Females

Parameter HR [95% CI] p-value
K11_CHOLANGI_STRICT 2.908 [2.29, 3.7] < 0.001
Birth year 0.997 [0.99, 1.01] 0.435

During the follow-up period (1.1.1998 — 31.12.2019), 280 out of 1127 females with K11_CHOLANGI_STRICT died.

Males

Parameter HR [95% CI] p-value
K11_CHOLANGI_STRICT 2.237 [1.71, 2.93] < 0.001
Birth year 0.987 [0.98, 1.0] 0.008

During the follow-up period (1.1.1998 — 31.12.2019), 180 out of 971 males with K11_CHOLANGI_STRICT died.

Mortality risk

Mortality risk for people of age

years, who have K11_CHOLANGI_STRICT.

N-year risk Females Males
1 0.293% 0.479%
5 1.856% 2.601%
10 4.805% 6.542%
15 8.555% 12.088%
20 14.957% 19.247%

Relationships between endpoints

Index endpoint: K11_CHOLANGI_STRICT – Cholangitis (primary sclerosing, PSC), with reimbursement 202

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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