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This is a non-core endpoint: only basic statistics are computed.

Hand

Z21_HAND

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 ZA4.0
  • Cause of death: ICD-10 ZA4.0

2 out of 7 registries used, show all original rules.

219

4. Check minimum number of events

None

219

5. Include endpoints

None

219

6. Filter based on genotype QC (FinnGen only)

202

Control definitions (FinnGen only)

Control exclude
Z21_ADDIT_CODES_LOCAT_DEFECT_INJURY_ILLNE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Z[AB]

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 202 125 77
Unadjusted period prevalence (%) 0.04 0.04 0.04
Median age at first event (years) 55.34 54.29 57.05

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
208
Matched controls
2080
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
ZA4.0
ICD-10 Finland
Hand
4503599627370496.0
293.5
207
*
SPAT1104
SPAT
Monitoring of emergency patient
6.8
19.9
34
58
-31
ICPC
Medical examin/health eval partial
6.7
19.0
33
57
-48
ICPC
Clarification/discussion RFE/demand
18.7
16.6
25
15
L12
ICPC
Hand/finger symptom/complaint
3.7
16.3
68
241
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.9
15.3
54
170
L11
ICPC
Wrist symptom/complaint
4.2
12.9
39
109
-60
ICPC
Result test/procedure
5.8
12.8
25
48
ACC51
NOMESCO Finland
Release of median nerve
4.7
12.8
32
77
Z01.8
ICD-10 Finland
Other specified special examinations
3.1
12.6
69
285
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
3.8
12.5
44
137
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.7
10.9
39
122
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
5.1
10.0
22
47
WYA00
NOMESCO Finland
Screening and health check-up
14.3
9.8
16
12
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.2
9.8
45
165
-57
ICPC
Physical medicine/rehabilitation
57.8
9.7
11
*
SPAT1097
SPAT
Recording of ECG
3.3
9.7
43
154
SPAT1254
SPAT
Administration of medicine
3.3
9.3
39
135
Z25.1
ICD-10 Finland
Need for immunization against influenza
4.6
9.2
23
55
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.5
8.6
70
346
Z20.9
ICD-10 Finland
Contact with and exposure to unspecified communicable disease
7.3
8.6
20
30
N02AX02
ATC
tramadol; systemic, rectal
2.3
8.4
104
621
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.3
7.7
93
544
L81
ICPC
Injury musculoskeletal NOS
9.4
7.7
15
17
-56
ICPC
Dressing/pressure/compress/tamponade
19.3
7.7
11
6
EB1CA
NOMESCO Finland
Tooth X-ray additional picture
3.0
7.7
37
139
L01
ICPC
Neck symptom/complaint
2.7
7.6
48
208
Z29.8
ICD-10 Finland
Other specified prophylactic measures
6.9
7.6
18
28
-34
ICPC
Blood test
8.9
7.5
15
18
L86
ICPC
Back syndrome with radiating pain
4.0
7.4
22
60
R04
ICPC
Breathing problem other
4.2
7.3
20
51
X58
ICD-10 Finland
Exposure to other specified factors
2.7
7.3
44
186
-50
ICPC
Medication/prescr/renewal
6.0
7.3
19
34
-35
ICPC
Urine test
31.2
7.2
9
*
L15
ICPC
Knee symptom/complaint
2.3
7.1
68
359
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
4.2
6.9
19
49
SPAT1249
SPAT
Treatment-related counselling outside office
2.2
6.8
92
558
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.7
6.8
41
174
R4110, ,
SPAT
2.6
6.6
42
182
-54
ICPC
Repair/fix-suture/cast/prosth device
10.5
6.6
12
12
-42
ICPC
Electrical tracing
14.9
6.5
10
7
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.9
6.3
32
123
ND1AA
NOMESCO Finland
Wrist X-ray examination
3.3
6.3
25
83
-43
ICPC
Other diagnostic procedure
18.7
6.3
9
5
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
6.6
6.3
15
24
N03AX16
ATC
[U] pregabalin
2.3
6.3
59
307
N17
ICPC
Vertigo/dizziness
2.7
6.2
35
143
S61.1
ICD-10 Finland
Open wound of finger(s) with damage to nail
10.5
6.1
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
104
563
2.69
11.16
2.6
2.7
55.16
64.69
u/l
0.57
104
529
25
66
4.17
8.81
3.9
2.7
—
—
—
0
0
22
57
4.20
7.93
3.1
3.4
683.33
252.26
mg/l
—
6
23
30
98
3.41
7.80
3.7
2.7
7.43
7.42
ph
1.13
23
79
68
358
2.34
7.12
1.3
1.3
13.79
8.94
u/ml
0.16
25
140
55
265
2.46
7.00
2.6
2.5
227.61
117.59
ug/g
0.60
44
210
98
636
2.02
5.79
4.4
3.5
31.64
34.32
ng/l
0.09
73
410
175
1415
2.49
5.65
5.1
4.4
14.84
14.56
pmol/l
0.75
170
1309
13
21
6.53
5.48
2.3
1.6
—
—
—
0
0
201
1807
4.34
5.20
20.5
13.9
21.35
22.36
mg/l
0.18
183
1469
130
963
1.93
4.94
5.2
6.4
11.28
11.10
umol/l
0.05
124
922
22
80
2.96
4.78
1.9
1.6
—
—
—
0
0
50
273
2.09
4.58
1.4
1.5
524.00
547.04
titre
—
10
71
71
449
1.88
4.25
3.2
3.6
1.02
1.02
kg/l
0.26
55
291
116
863
1.78
4.01
11.5
7.6
1.22
1.21
mmol/l
0.99
109
754
63
392
1.87
3.93
1.4
1.3
11.73
33.41
iu/ml
2.93
21
130
80
539
1.79
3.84
3.9
3.7
0.00
0.00
estimate
-0.00
14
185
21
88
2.54
3.52
2.0
2.3
0.00
0.00
estimate
—
7
30
31
157
2.15
3.42
1.2
1.2
—
—
—
0
0
132
1047
1.71
3.40
5.6
5.2
6.63
6.52
mmol/l
0.15
126
985
7
11
6.54
3.21
2.3
1.0
—
—
—
0
0
190
1701
2.35
3.14
5.2
4.1
1.28
1.27
mmol/l
0.09
183
1597
189
1690
2.30
3.10
6.8
5.8
39.03
38.66
mmol/mol
0.21
184
1610
6
8
7.68
3.07
3.2
1.4
136.83
51.85
ng/l
—
6
8
45
272
1.84
3.02
3.6
2.9
5.50
2.54
e6/l
1.04
31
128
68
465
1.69
2.98
1.3
1.3
0.47
1.86
u/ml
1.93
17
134
157
1329
1.74
2.96
3.7
3.3
36.38
44.36
u/l
1.38
151
1273
31
167
2.01
2.91
3.0
1.9
5.95
6.14
ph
0.48
22
110
41
246
1.83
2.81
3.0
2.1
—
—
—
0
0
6
10
6.14
2.71
2.7
3.4
—
—
—
0
0
195
1789
2.44
2.61
5.7
4.8
1.46
1.48
mmol/l
0.33
187
1693
195
1792
2.41
2.54
5.9
4.9
4.61
4.69
mmol/l
0.48
190
1701
37
222
1.81
2.53
11.8
5.9
1.02
1.03
mmol/l
0.10
37
206
22
112
2.08
2.41
2.4
1.9
—
—
—
0
0
28
156
1.92
2.40
6.6
4.8
0.64
0.88
%
0.17
14
44
78
580
1.55
2.35
3.2
2.3
—
—
—
0
0
196
1816
2.37
2.31
6.2
5.5
2.74
2.76
mmol/l
0.10
190
1719
64
457
1.58
2.29
4.2
4.0
—
—
—
0
0
98
772
1.51
2.24
12.6
10.6
1.15
1.18
inr
0.25
83
618
5
9
5.66
2.22
1.8
1.1
4.92
8.30
mmol/l
—
5
9
6
14
4.38
2.16
1.0
1.1
—
—
—
0
0
79
598
1.52
2.16
7.9
6.0
—
—
—
0
0
26
147
1.88
2.14
5.6
4.7
0.65
0.49
%
0.18
13
35
37
234
1.71
2.12
1.3
1.3
—
—
—
0
0
28
163
1.83
2.11
1.9
2.1
0.00
0.00
estimate
—
8
36
120
996
1.48
2.06
4.1
3.6
0.00
0.00
estimate
-0.00
16
198
42
277
1.65
2.06
4.5
2.3
2.44
2.34
g/l
0.58
42
255
85
660
1.49
2.03
5.5
3.8
37.11
68.18
e6/l
0.42
62
450
25
143
1.85
2.00
6.4
3.3
73.01
79.80
ng/l
0.16
25
130
96
771
1.46
1.91
2.5
2.0
108.15
96.05
pmol/l
1.13
62
384
26
153
1.80
1.90
6.7
5.1
0.50
0.31
%
0.13
12
32
38
251
1.63
1.85
4.2
2.4
23.56
23.64
%
0.02
38
236
74
570
1.46
1.81
4.1
2.9
0.00
0.00
estimate
—
9
161
25
148
1.78
1.80
7.3
5.0
0.00
0.11
%
1.36
11
35
38
254
1.61
1.77
1.9
1.6
1005.38
1164.06
nmol/l
0.66
33
199
91
735
1.42
1.71
2.1
2.0
—
—
—
0
0
33
215
1.64
1.70
1.5
1.4
—
—
—
0
0
7
25
2.86
1.66
1.0
1.2
—
—
—
0
0
198
1873
2.19
1.66
19.1
12.3
—
—
—
0
0
77
606
1.43
1.66
2.4
3.3
2.35
2.35
mmol/l
0.12
72
553
43
302
1.53
1.63
4.5
2.4
15.20
14.00
umol/l
0.47
43
282
16
85
1.96
1.60
1.2
1.3
—
1.92
—
0
5
11
50
2.27
1.60
1.4
1.3
—
—
—
0
0
46
330
1.51
1.58
1.7
1.8
389.33
39661485.72
pmol/l
0.50
39
295
92
755
1.39
1.54
6.0
4.8
36.97
36.12
g/l
0.95
86
720
23
142
1.70
1.46
2.3
3.1
75.03
71.84
e9/l
0.18
17
100
20
119
1.75
1.44
1.4
1.3
240.25
554.90
u/ml
0.60
20
108
7
29
2.46
1.40
1.0
1.2
—
—
—
0
0
114
981
1.36
1.37
4.1
3.6
0.00
0.00
estimate
-0.00
16
194
6
23
2.65
1.37
1.3
1.3
—
—
—
0
0
5
17
2.99
1.36
3.0
2.9
—
—
—
0
0
56
430
1.41
1.35
1.4
1.3
2.18
2.29
g/l
0.17
36
269
6
24
2.54
1.31
1.0
1.3
240.00
251.84
mu/l
—
6
19
145
1583
0.72
1.30
23.7
17.9
333.08
332.79
g/l
0.15
145
1578
115
1002
1.33
1.23
4.1
3.7
0.00
0.00
estimate
-0.00
16
186
6
26
2.35
1.19
2.3
1.3
—
—
—
0
0
34
244
1.47
1.17
1.8
1.6
—
—
—
0
0
15
89
1.74
1.11
3.3
10.2
—
—
—
0
0
90
766
1.31
1.10
4.0
3.4
0.00
0.01
estimate
—
8
167
5
21
2.41
1.09
1.0
1.0
—
—
—
0
0
5
21
2.41
1.09
1.4
1.3
—
—
—
0
0
120
1063
1.30
1.09
7.7
9.7
4.34
3.97
e9/l
0.76
113
926
67
549
1.33
1.07
7.7
6.0
—
—
—
0
0
17
107
1.64
1.03
1.1
1.2
—
—
—
0
0
21
143
1.52
0.94
2.8
2.2
68.04
67.29
g/l
0.21
21
137
34
256
1.39
0.93
1.6
1.6
—
—
—
0
0
26
187
1.45
0.90
6.9
11.0
1.26
0.87
mmol/l
0.25
20
158
6
29
2.10
0.90
3.2
3.3
3.94
4.72
e9/l
—
6
29
27
196
1.43
0.90
1.8
1.9
366.63
386.30
nmol/l
0.27
27
184
8
42
1.94
0.89
1.1
1.1
—
—
—
0
0
14
88
1.63
0.87
2.1
1.5
—
—
—
0
0
29
215
1.41
0.86
2.3
1.6
—
—
—
0
0
23
163
1.46
0.86
1.7
2.6
0.24
0.22
g/l
0.84
23
149
16
105
1.57
0.84
3.4
4.3
4.61
4.51
pmol/l
0.17
16
95
62
519
1.28
0.83
3.1
2.7
—
—
—
0
0
72
614
1.26
0.83
4.2
3.3
7.99
7.84
mmol/l
0.11
66
532
107
957
1.24
0.81
7.0
6.2
0.58
0.56
e9/l
0.40
102
825
107
961
1.23
0.77
7.1
6.2
0.04
0.04
e9/l
0.33
102
826
13
83
1.60
0.77
1.2
1.2
—
—
—
0
0
8
132
0.59
0.76
7.9
3.5
—
—
—
0
0
7
38
1.87
0.74
2.9
2.8
59.43
60.71
%
—
7
38
10
60
1.70
0.73
2.7
2.0
—
—
—
0
0
10
60
1.70
0.73
1.1
1.5
—
—
—
0
0
12
76
1.61
0.73
2.4
1.5
—
—
—
0
0
38
304
1.31
0.72
3.0
3.7
0.83
0.81
mmol/l
0.34
38
293
7
42
1.69
0.69
3.6
1.6
—
—
—
0
0
108
979
1.21
0.69
7.0
6.3
1.97
1.95
e9/l
0.05
103
866
12
78
1.57
0.67
1.3
1.5
—
—
—
0
0
44
363
1.27
0.66
1.7
1.7
—
—
—
0
0
11
70
1.60
0.66
1.3
1.3
—
—
—
0
0
14
95
1.51
0.66
2.4
1.5
—
—
—
0
0
14
95
1.51
0.66
2.2
1.5
—
—
—
0
0
67
582
1.22
0.65
5.3
4.1
16.90
11.35
mg/mmol
0.28
44
360
14
96
1.49
0.63
2.2
1.5
—
—
—
0
0
14
97
1.48
0.60
2.4
1.5
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
20
149
1.38
0.60
1.3
1.3
211.75
130.50
u/ml
—
8
66
22
167
1.35
0.60
1.7
1.5
—
—
—
0
0
12
172
0.68
0.59
16.8
3.1
5.70
5.75
kpa
0.09
12
167
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
11
159
0.67
0.56
27.6
7.9
—
—
—
0
0
65
571
1.20
0.56
4.4
3.1
12.92
156.04
e6/l
0.68
55
434
17
125
1.39
0.55
1.1
1.4
—
32.07
—
0
9
28
224
1.29
0.54
1.4
1.3
—
—
—
0
0
9
62
1.47
0.54
3.2
2.8
—
—
—
0
0
6
39
1.55
0.53
1.8
2.3
130.00
127.59
g/l
—
6
27
47
545
0.82
0.53
9.7
3.7
7.39
7.39
ph
0.35
33
381
87
788
1.18
0.53
3.3
3.3
6.14
6.16
ph
0.07
53
452
13
92
1.44
0.52
1.0
1.1
—
—
—
0
0
107
989
1.17
0.50
7.0
6.5
0.21
0.19
e9/l
0.73
101
867
7
45
1.57
0.49
1.3
4.0
—
—
—
0
0
24
192
1.28
0.47
7.5
10.9
7.41
7.42
ph
0.49
18
106
39
455
0.82
0.47
4.6
4.8
—
—
—
0
0
48
418
1.19
0.45
2.5
1.7
1.12
1.18
mg/l
0.07
38
332
63
566
1.16
0.41
4.3
3.5
127.94
67.24
mg/l
0.52
44
367
0
15
0.00
0.41
0.0
3.3
—
41.09
—
0
7
0
15
0.00
0.41
0.0
1.1
—
0.08
—
0
9
7
101
0.68
0.40
14.1
2.3
1.37
1.40
%
—
7
101
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
5
35
1.44
0.39
3.0
1.6
—
—
—
0
0
5
37
1.36
0.37
1.6
1.8
6.45
4.86
mmol/24h
—
5
32
6
44
1.37
0.34
1.3
1.3
—
—
—
0
0
6
46
1.31
0.33
5.8
1.4
1.39
0.84
nmol/l
—
6
40
27
230
1.20
0.33
1.3
1.3
—
—
—
0
0
7
99
0.70
0.31
14.1
2.3
0.57
0.62
%
—
7
99
7
54
1.31
0.30
1.0
1.3
—
—
—
0
0
91
857
1.11
0.28
3.6
2.7
—
—
estimate
—
0
0
6
82
0.72
0.24
1.3
1.1
1.01
0.87
g/l
—
6
82
5
41
1.22
0.22
3.8
2.3
1134.04
126.38
ug/min
—
5
22
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
12
145
0.82
0.21
10.1
2.6
4.83
4.51
kpa
0.21
12
140
0
11
0.00
0.21
0.0
1.2
—
183.97
—
0
11
0
10
0.00
0.21
0.0
1.5
—
57.20
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
17
145
1.19
0.21
1.2
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
3.0
—
36.86
—
0
7
0
12
0.00
0.21
0.0
2.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
5
43
1.17
0.21
2.4
3.6
7.40
7.42
ph
—
5
43
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
77
809
0.92
0.19
1.7
1.9
1.35
1.35
mmol/l
0.01
71
701
15
174
0.85
0.18
1.8
1.8
3.98
3.41
mmol/l
—
9
128
7
59
1.19
0.18
1.3
1.1
—
—
—
0
0
13
110
1.19
0.17
1.9
1.8
—
—
—
0
0
5
67
0.74
0.17
1.2
1.2
14.02
8.84
u/l
—
5
55
58
548
1.08
0.16
1.6
1.5
—
—
—
0
0
6
80
0.74
0.15
1.3
1.1
1.47
1.55
g/l
—
6
80
9
81
1.12
0.15
2.2
2.1
—
—
—
0
0
9
105
0.85
0.13
1.0
1.1
—
—
—
0
0
12
104
1.16
0.12
1.8
1.3
35.50
24.12
iu/l
0.49
12
88
10
116
0.86
0.12
10.6
3.1
126.60
131.59
g/l
—
10
111
47
495
0.93
0.12
4.2
3.0
0.05
0.37
e6/l
3.21
38
360
24
221
1.10
0.11
1.5
1.8
—
—
—
0
0
10
115
0.86
0.11
18.7
8.2
24.15
24.92
mmol/l
—
10
115
6
54
1.11
0.09
1.2
1.2
—
—
—
0
0
6
58
1.04
0.08
1.0
1.7
—
—
—
0
0
8
75
1.07
0.07
2.3
1.6
362.00
288.23
mu/l
—
8
69
8
77
1.04
0.07
2.3
2.1
1.58
1.46
g/l
—
8
71
27
256
1.06
0.06
1.3
2.0
—
—
—
0
0
25
264
0.94
0.06
1.8
1.5
—
—
—
0
0
34
354
0.95
0.06
4.1
3.7
12.13
382.95
ng/l
1.76
23
260
12
110
1.10
0.05
1.3
1.3
—
—
—
0
0
43
442
0.97
0.04
1.8
2.1
—
—
—
0
0
21
202
1.04
0.02
1.4
1.5
—
—
—
0
0
23
238
0.96
0.02
10.9
7.1
105.65
104.38
mmol/l
0.72
23
238
82
813
1.01
0.01
12.0
11.1
0.00
0.00
e9/l
0.54
74
656
31
311
1.00
0.00
3.5
2.9
0.68
0.72
ug/l
0.15
21
183
75
752
1.00
0.00
3.4
2.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
5
50
1.00
0.00
2.4
1.2
—
—
—
0
0
7
73
0.96
-0.00
2.9
4.4
37.00
36.97
°c
—
7
73
0
5
0.00
-0.00
0.0
3.0
—
3.40
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
6.32
—
0
5
0
5
0.00
-0.00
0.0
10.6
—
24.06
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
2099.17
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
0.02
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
31.54
—
0
5

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: Z21_HAND – Hand

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).