eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]
Postprocedural disorders of ear and mastoid process, not elsewhere classified
DOID EFO Endpoint Browser PheWeb
H8_POSTOP
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
332 |
6. Filter based on genotype QC (FinnGen only) |
280 |
Control definitions (FinnGen only)
- Control exclude
- H8_OTHEREAR
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Postprocedural disorders of ear and mastoid process, not elsewhere classified
based on the number of shared cases.
Similar with more cases:
- Other disorders of ear
- Diseases of the ear and mastoid process
- Any operation in hilmo
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2836 | 1357 | 1468 |
| Only index persons | 2677 | 1286 | 1391 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.04 |
| Only index persons | 0.05 | 0.05 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 61.03 | 64.13 | 58.11 |
| Only index persons | 60.48 | 63.48 | 57.72 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 280 | 133 | 147 |
| Unadjusted period prevalence (%) | 0.06 | 0.05 | 0.07 |
| Median age at first event (years) | 61.77 | 60.77 | 62.67 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 299
- Matched controls
- 2990
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
UDC00
NOMESCO Finland
Ear microscopy
81.9
305.1
181
55
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
75.1
196.9
110
23
H71
ICD-10 Finland
Cholesteatoma of middle ear
509.2
181.7
164
7
H95.1
ICD-10 Finland
Other disorders following mastoidectomy
+∞
165.4
143
*
DFF00
NOMESCO Finland
Pure tone audiometry
29.1
151.5
114
62
H95.0
ICD-10 Finland
Recurrent cholesteatoma of postmastoidectomy cavity
+∞
125.0
111
*
H95.8
ICD-10 Finland
Other postprocedural disorders of ear and mastoid process
1158.3
90.7
84
*
DAX08
NOMESCO Finland
Fitting of hearing aid
38.1
87.8
56
18
Z01.1
ICD-10 Finland
Examination of ears and hearing
12.3
87.2
106
128
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
43.8
78.6
48
13
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
+∞
75.2
69
*
Z97.4
ICD-10 Finland
Presence of external hearing-aid
32.6
70.6
47
17
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
19.7
70.3
58
36
DFF15
NOMESCO Finland
Speech audiometry
24.4
68.6
51
25
H65.3
ICD-10 Finland
Chronic mucoid otitis media
31.5
61.2
41
15
H66.9
ICD-10 Finland
Otitis media, unspecified
12.3
58.1
64
65
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
93.4
49.9
54
7
38700
ICD-8 Finland
Other disease of ear and mastoid process, Cholesteatoma of ear
180.4
45.2
46
*
3853A
ICD-9 Finland
Other disorders of middle ear and mastoid, Cholesteatoma of middle ear and mastoid
175.8
44.1
45
*
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
243.3
42.0
42
*
H66.0
ICD-10 Finland
Acute suppurative otitis media
8.5
41.5
60
86
H60.9
ICD-10 Finland
Otitis externa, unspecified
9.0
40.9
56
75
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
83.2
39.1
43
6
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic
16.7
38.0
33
22
H66.4
ICD-10 Finland
Suppurative otitis media, unspecified
63.7
34.2
39
7
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
81.3
32.7
36
5
S02CA02
ATC
flumetasone and antiinfectives; otic
7.3
31.5
51
82
DEB25
NOMESCO Finland
Attico-antro-mastoidectomy and tympanoplasty
347.4
31.5
31
*
38210
ICD-8 Finland
Chronic otitis media with mastoiditis
347.4
31.5
31
*
DEA10
NOMESCO Finland
Attico-antrotomy
+∞
30.8
29
*
H90.1
ICD-10 Finland
Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
334.4
30.4
30
*
WX720
NOMESCO Finland
Own respiration
8.0
30.1
44
63
H70.1
ICD-10 Finland
Chronic mastoiditis
+∞
29.7
28
*
H90.7
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
+∞
29.7
28
*
DBD20
NOMESCO Finland
Plastic repair of external auditory canal
114.9
29.3
31
*
DEB30
NOMESCO Finland
Radical mastoidectomy
166.1
29.2
30
*
WX704
NOMESCO Finland
Intubation
6.1
28.9
57
112
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
5.1
28.1
69
165
DCD00
NOMESCO Finland
Myringoplasty
106.7
27.2
29
*
H95.9
ICD-10 Finland
Postprocedural disorder of ear and mastoid process, unspecified
+∞
26.4
25
*
H74.1
ICD-10 Finland
Adhesive middle ear disease
+∞
25.4
24
*
WX725
NOMESCO Finland
Noninvasive ventilation
6.4
24.6
44
78
TDA90
NOMESCO Finland
Removal wax from ear
51.3
23.8
28
6
DC1AD
NOMESCO Finland
Temporalbone CT
59.1
23.5
27
5
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
67.9
22.2
25
*
DCD10
NOMESCO Finland
Tympanoplasty
236.6
21.9
22
*
4147
FHL
Radical surgery, cavity filling and middle ear and / or eardrum plastic
124.1
21.9
23
*
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
19.1
20.5
31
18
Z97.8
ICD-10 Finland
Presence of other specified devices
74.9
19.0
21
*
DEB20
NOMESCO Finland
Attico-antro-mastoidectomy and tympanotomy
+∞
19.0
18
*
H72.2
ICD-10 Finland
Other marginal perforations of tympanic membrane
56.2
18.2
21
*
3821A
ICD-9 Finland
Suppurative and unspecified otitis media, Chronic tubotympanic suppurative otitis media
101.1
17.8
19
*
4151
FHL
Reoperation for chronic otitis media
+∞
16.8
16
*
H65.2
ICD-10 Finland
Chronic serous otitis media
26.2
16.3
22
9
H65.4
ICD-10 Finland
Other chronic nonsuppurative otitis media
50.5
16.2
19
*
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
18.5
15.9
24
14
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.8
15.7
113
532
WX702
NOMESCO Finland
Supraglottic ventilation device
5.1
15.6
35
76
Z01.8
ICD-10 Finland
Other specified special examinations
2.9
15.5
95
411
H92.0
ICD-10 Finland
Otalgia
6.0
15.1
28
51
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
44.8
14.3
17
*
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
11.8
13.8
25
23
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.1
13.6
40
108
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
22.4
13.5
19
9
H73.1
ICD-10 Finland
Chronic myringitis
+∞
12.6
12
*
H74.2
ICD-10 Finland
Discontinuity and dislocation of ear ossicles
135.5
12.5
13
*
H60.4
ICD-10 Finland
Cholesteatoma of external ear
135.5
12.5
13
*
Z98.8
ICD-10 Finland
Other specified postsurgical states
15.2
12.5
20
14
H60.3
ICD-10 Finland
Other infective otitis externa
10.7
12.2
23
23
H93.1
ICD-10 Finland
Tinnitus
11.8
11.7
21
19
H60.8
ICD-10 Finland
Other otitis externa
6.0
11.6
21
37
4150
FHL
Tympanoplasty (including for reasons other than inflammation)
+∞
11.5
11
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.7
11.4
73
317
J01DA09
ATC
[U] cefadroxil
2.5
11.2
97
488
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.3
10.9
172
1114
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
3.1
10.8
50
182
ZZG00
NOMESCO Finland
Graft of cartilage
+∞
10.5
10
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.7
10.4
66
285
H90.8
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, unspecified
41.6
10.0
12
*
H72.9
ICD-10 Finland
Perforation of tympanic membrane, unspecified
20.9
9.9
14
7
H91.1
ICD-10 Finland
Presbycusis
5.6
9.8
19
36
ICB01, ,
SPAT
56.9
9.7
11
*
DEB10
NOMESCO Finland
Attico-antro-mastoidectomy
103.2
9.5
10
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
9.0
86
446
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
+∞
8.4
8
*
H66.2
ICD-10 Finland
Chronic atticoantral suppurative otitis media
+∞
8.4
8
*
DED00
NOMESCO Finland
Obliteration of cavity after partial excision of mastoid
+∞
8.4
8
*
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
4.8
8.2
19
42
J01MA02
ATC
ciprofloxacin; systemic
2.0
8.2
137
877
H69.0
ICD-10 Finland
Patulous Eustachian tube
17.8
8.1
12
7
R5120
NOMESCO Finland
Preparation of an aid
7.8
7.8
17
23
XQ855, ,
SPAT
15.6
7.8
12
8
H04
ICPC
Ear discharge
4.7
7.8
18
40
DGW00
NOMESCO Finland
Dilatation of eustachian tube
46.2
7.8
9
*
H72.1
ICD-10 Finland
Attic perforation of tympanic membrane
46.2
7.8
9
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.5
7.5
50
219
H65.9
ICD-10 Finland
Nonsuppurative otitis media, unspecified
30.8
7.2
9
*
Z3229
NOMESCO Finland
Other healthcare associate professional
3.1
7.1
31
108
-31
ICPC
Medical examin/health eval partial
3.1
7.0
30
104
SPAT1301
SPAT
No procedures
2.0
6.9
112
700
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.9
6.9
120
768
H61.2
ICD-10 Finland
Impacted cerumen
3.1
6.9
30
105
WZC00, ,
SPAT
2.4
6.8
50
230
N03AX12
ATC
[U] gabapentin; oral
2.3
6.8
60
299
H01
ICPC
Ear pain/earache
2.7
6.8
38
153
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic
5.7
6.7
18
33
H61.8
ICD-10 Finland
Other specified disorders of external ear
12.6
6.6
11
9
4141
FHL
Myringoplasty (also for reasons other than inflammation)
71.3
6.4
7
*
SPAT1097
SPAT
Recording of ECG
2.2
6.4
57
285
H90.5
ICD-10 Finland
Sensorineural hearing loss, unspecified
18.5
6.3
9
5
WYA20, ,
SPAT
18.5
6.3
9
5
DEB00
NOMESCO Finland
Cortical mastoidectomy
+∞
6.3
6
*
H61.3
ICD-10 Finland
Acquired stenosis of external ear canal
27.3
6.3
8
*
WVA20, ,
SPAT
4.1
6.3
17
43
R5140
NOMESCO Finland
Monitoring the use of the aid
2.6
6.2
36
147
J01DA06
ATC
[U] cefuroxime
2.3
6.2
52
253
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
12.9
6.1
10
8
S02AA03
ATC
boric acid; otic
12.9
6.1
10
8
EBB10
NOMESCO Finland
Insertion of dental implant
12.9
6.1
10
8
H65.0
ICD-10 Finland
Acute serous otitis media
8.9
6.1
12
14
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
5.8
6.1
16
29
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
103
610
2.05
7.54
5.0
4.3
1.02
1.02
kg/l
0.83
79
432
96
559
2.06
7.32
5.9
4.2
23.94
277.08
ng/l
2.82
88
465
72
380
2.18
7.07
2.6
1.9
—
—
—
0
0
69
367
2.14
6.61
2.5
1.9
—
—
—
0
0
68
376
2.05
5.84
7.0
7.3
2.74
0.99
mmol/l
3.19
53
312
20
64
3.28
5.29
2.1
2.0
—
—
—
0
0
81
502
1.84
4.90
2.6
1.9
—
—
—
0
0
125
904
1.66
4.29
4.3
3.4
7.26
7.35
mmol/l
0.08
112
755
122
892
1.62
3.93
3.6
4.2
12.53
12.08
mg/mmol
0.03
68
568
9
16
5.76
3.68
1.2
1.3
—
—
—
0
0
53
819
0.57
3.40
4.5
3.4
0.50
0.43
e6/l
0.08
41
614
8
235
0.32
3.36
2.5
3.3
1.21
1.22
mmol/l
—
8
207
115
856
1.56
3.31
4.3
3.3
30.16
34.93
u/l
0.51
109
813
171
1406
1.51
3.01
7.0
6.8
10.64
12.08
umol/l
1.61
166
1347
164
1342
1.49
2.92
19.7
16.0
1.35
1.31
inr
0.37
143
1122
158
1289
1.48
2.82
6.8
6.4
1.21
1.21
mmol/l
0.17
149
1190
23
112
2.14
2.75
3.6
2.8
—
—
—
0
0
222
1952
1.53
2.65
32.2
24.1
332.12
331.29
g/l
0.81
222
1943
37
593
0.57
2.64
2.4
2.8
2.48
2.45
mmol/l
0.44
28
534
76
1026
0.65
2.63
4.4
3.4
—
—
—
0
0
38
225
1.79
2.62
2.1
1.7
—
—
—
0
0
209
2326
0.66
2.60
16.2
17.8
75.09
76.80
ml/min/173m2
0.51
187
2162
184
1563
1.46
2.57
6.1
5.2
6.94
6.77
mmol/l
0.53
175
1491
250
2265
1.63
2.54
5.3
5.4
2.17
1.96
mu/l
1.48
231
2054
167
1405
1.43
2.38
9.2
7.3
1.21
1.21
mmol/l
0.26
153
1201
11
40
2.82
2.30
4.5
2.1
12.36
9.80
mmol/l
0.97
11
40
214
1893
1.46
2.26
4.1
4.3
14.71
14.96
pmol/l
0.81
200
1708
37
568
0.60
2.21
3.1
3.2
0.65
0.78
ug/l
1.11
23
383
16
309
0.49
2.10
2.2
3.5
—
—
—
0
0
30
471
0.60
1.95
3.8
3.3
2.06
2.33
e6/l
0.12
20
242
253
2341
1.52
1.88
5.8
5.4
5.96
6.03
mmol/l
0.42
241
2118
144
1223
1.34
1.75
6.1
4.8
34.10
35.04
g/l
1.12
128
1161
178
1562
1.34
1.72
3.7
3.2
57.48
51.31
u/l
0.32
163
1470
59
780
0.70
1.71
6.0
4.2
0.00
0.00
estimate
—
9
254
48
644
0.70
1.49
2.6
2.5
—
—
—
0
0
74
582
1.36
1.45
1.6
1.8
214925739.69
11850735.96
pmol/l
0.73
67
481
141
1220
1.29
1.41
2.3
2.3
90.95
94.94
pmol/l
0.57
77
636
5
124
0.39
1.40
1.6
1.3
—
—
—
0
0
204
1855
1.31
1.39
5.3
4.5
15.38
13.78
mm/h
0.71
195
1709
5
17
2.97
1.36
1.6
1.5
—
—
—
0
0
5
17
2.97
1.36
1.6
1.5
—
—
—
0
0
153
1344
1.28
1.34
3.1
2.8
—
—
—
0
0
118
1006
1.29
1.30
2.3
1.9
1.39
1.32
mmol/l
0.44
102
835
14
78
1.83
1.23
1.2
1.3
—
—
—
0
0
6
26
2.33
1.19
4.0
3.2
14.67
3.50
nmol/l
—
6
26
10
50
2.03
1.18
1.5
1.4
—
—
—
0
0
0
33
0.00
1.17
0.0
1.2
—
—
—
0
0
5
20
2.52
1.15
1.0
1.2
—
—
—
0
0
16
254
0.61
1.12
3.6
3.1
4.57
4.35
kpa
0.23
16
244
265
2530
1.42
1.11
13.7
12.6
25.16
24.93
u/l
0.10
256
2451
41
307
1.39
1.09
1.1
1.4
—
—
—
0
0
244
2306
1.32
1.05
7.0
6.9
39.85
39.95
mmol/mol
0.06
229
2141
63
508
1.30
1.05
1.6
1.8
1013.35
1216.00
nmol/l
1.36
52
390
253
2408
1.33
0.99
22.6
18.0
22.79
26.19
mg/l
1.06
220
2031
5
23
2.19
0.98
2.0
1.9
—
—
—
0
0
18
268
0.65
0.97
11.7
7.3
1.32
1.39
mmol/l
0.19
18
263
116
1017
1.23
0.96
4.8
4.1
0.00
0.01
estimate
—
5
233
8
146
0.54
0.95
1.4
1.3
—
39.04
—
0
13
7
37
1.91
0.94
1.4
2.4
7.06
103.31
u/ml
—
7
37
6
28
2.17
0.92
1.0
1.1
—
—
—
0
0
11
63
1.77
0.91
1.5
1.3
—
—
—
0
0
12
72
1.69
0.86
1.4
1.6
—
—
—
0
0
188
1745
1.21
0.83
6.3
5.0
—
2670.74
—
0
34
151
1376
1.20
0.81
4.8
4.1
0.00
12.29
estimate
—
10
285
251
2405
1.27
0.79
6.4
6.0
2.55
2.59
mmol/l
0.33
231
2203
32
246
1.34
0.76
3.3
3.6
88.92
86.94
ng/l
0.06
32
219
41
506
0.78
0.74
3.3
3.2
0.65
1.00
e6/l
0.90
31
277
132
1198
1.18
0.72
3.1
2.8
—
—
estimate
—
0
0
5
26
1.94
0.71
1.0
1.5
62.46
48.26
ug/l
—
5
26
10
61
1.66
0.69
2.5
3.1
0.69
0.99
nmol/l
—
10
49
12
177
0.66
0.65
10.3
7.7
24.34
24.93
mmol/l
0.34
12
177
14
200
0.69
0.65
2.1
1.8
—
—
—
0
0
86
968
0.84
0.65
2.6
3.5
2.36
2.35
mmol/l
0.14
76
880
11
71
1.57
0.63
1.5
1.4
—
—
—
0
0
244
2348
1.21
0.61
5.5
5.2
4.48
4.49
mmol/l
0.03
225
2159
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
207
1969
1.17
0.58
9.3
8.4
82.93
79.48
u/l
0.36
199
1864
117
1068
1.16
0.57
3.6
4.2
110.46
88.81
ng/l
0.08
83
837
75
661
1.18
0.57
2.6
2.9
373.94
355.62
umol/l
0.72
67
573
64
559
1.18
0.54
1.7
1.8
1.71
1.53
mg/l
0.17
50
448
39
325
1.23
0.53
2.5
2.7
5.90
9.98
umol/l
1.83
34
288
24
302
0.78
0.53
3.3
3.9
5.48
5.81
kpa
0.93
24
294
6
98
0.60
0.53
1.7
1.8
—
—
—
0
0
102
937
1.13
0.45
3.6
3.5
1622.58
1477.15
ng/l
0.14
88
815
10
69
1.46
0.45
1.2
1.3
—
—
—
0
0
5
31
1.62
0.43
1.2
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
4.81
—
0
7
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
193.78
—
0
16
11
149
0.73
0.41
1.7
1.3
—
—
—
0
0
28
334
0.82
0.41
1.5
1.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
240
2333
1.15
0.39
5.3
5.1
1.39
1.45
mmol/l
1.53
221
2131
49
549
0.87
0.35
1.3
1.3
3.53
1.54
u/ml
0.31
11
138
6
44
1.37
0.34
1.2
1.4
—
—
—
0
0
6
45
1.34
0.34
1.3
1.1
0.82
0.88
nmol/l
—
6
36
22
263
0.82
0.34
1.5
2.6
61.67
66.34
g/l
1.65
22
241
6
47
1.28
0.32
1.2
1.3
—
—
—
0
0
8
107
0.74
0.29
1.6
2.0
—
—
—
0
0
39
436
0.88
0.28
1.6
1.3
16.35
36.28
iu/ml
1.64
17
141
123
1169
1.09
0.27
2.3
2.5
79.17
77.36
nmol/l
0.34
114
1029
5
72
0.69
0.26
2.6
1.9
142.20
128.00
g/l
—
5
53
15
181
0.82
0.26
1.5
2.0
—
—
—
0
0
13
159
0.81
0.25
3.7
2.8
0.58
0.63
%
0.39
13
159
38
421
0.89
0.24
8.6
7.1
104.63
104.16
mmol/l
0.22
38
421
35
316
1.12
0.21
5.0
5.0
30.95
32.08
%
0.34
21
188
0
11
0.00
0.21
0.0
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
16.83
—
0
6
0
11
0.00
0.21
0.0
1.3
—
105.20
—
0
11
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
11
0.00
0.21
0.0
1.6
—
112.18
—
0
11
0
11
0.00
0.21
0.0
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
141
1461
0.93
0.21
9.8
9.9
4.60
4.27
e9/l
0.68
130
1274
0
12
0.00
0.21
0.0
4.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
2.9
—
1019.25
—
0
12
36
396
0.90
0.21
1.4
1.3
1.57
11.18
u/ml
—
6
144
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
28
312
0.89
0.20
2.7
4.5
10.24
47.29
ug/l
0.81
23
267
77
728
1.08
0.19
4.1
3.5
0.00
0.11
estimate
—
6
227
87
827
1.07
0.19
1.7
1.8
18.04
20.32
nmol/l
0.68
79
687
7
58
1.21
0.18
1.1
1.4
—
244.66
—
0
26
13
110
1.19
0.17
2.4
1.3
0.09
0.36
mg/l
—
5
43
5
68
0.73
0.17
1.0
1.5
—
—
—
0
0
5
68
0.73
0.17
1.8
1.3
—
—
—
0
0
8
68
1.18
0.16
1.0
1.2
—
—
—
0
0
226
2223
1.07
0.16
4.2
4.4
1.42
1.25
mmol/l
0.82
210
2004
10
83
1.21
0.15
1.6
2.0
—
—
—
0
0
12
140
0.85
0.15
4.5
2.1
1.52
1.53
g/l
—
6
127
17
192
0.88
0.15
3.1
2.8
65.80
59.77
ml/min/173m2
—
10
88
17
150
1.14
0.15
1.1
1.2
27.41
156.95
u/ml
—
8
48
10
118
0.84
0.14
1.0
1.0
—
—
—
0
0
21
190
1.11
0.13
2.4
3.4
115.95
126.58
g/l
1.20
21
185
11
95
1.16
0.12
1.6
2.1
—
—
—
0
0
12
136
0.88
0.11
4.3
4.2
1.02
1.02
ratio
0.11
12
129
142
1391
1.04
0.10
5.0
4.1
0.00
1.13
estimate
—
10
266
18
197
0.91
0.10
1.5
2.1
—
—
—
0
0
5
47
1.06
0.09
1.4
1.3
—
—
—
0
0
5
48
1.04
0.09
1.0
7.4
—
607.00
—
0
9
5
48
1.04
0.09
1.6
1.2
—
—
—
0
0
6
56
1.07
0.08
1.7
1.3
—
—
—
0
0
77
747
1.04
0.08
5.0
4.9
24.99
21.89
%
0.86
36
379
7
65
1.08
0.08
1.3
1.2
—
—
—
0
0
6
74
0.81
0.07
1.0
1.2
—
—
—
0
0
7
82
0.85
0.07
1.3
1.7
—
—
—
0
0
15
162
0.92
0.06
3.7
2.8
1.38
1.14
%
0.65
15
162
17
159
1.07
0.05
1.8
4.1
1.55
1.78
mmol/l
0.07
12
128
22
209
1.06
0.04
1.7
1.5
—
—
—
0
0
33
342
0.96
0.04
5.2
4.8
287.88
247.85
u/l
0.58
33
323
96
948
1.02
0.03
5.1
5.9
6.83
2.42
ug/l
0.46
82
829
74
750
0.98
0.02
2.5
2.2
2.42
3.05
mg/l
1.95
68
648
10
102
0.98
0.00
1.6
1.3
—
—
—
0
0
29
292
0.99
0.00
13.7
8.0
—
—
—
0
0
136
1359
1.00
0.00
4.8
4.0
0.00
0.00
estimate
—
8
279
12
124
0.97
0.00
1.8
2.8
14.98
38.66
u/ml
1.31
12
119
5
52
0.96
0.00
1.4
1.1
—
8.62
—
0
5
5
56
0.89
0.00
1.8
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
8.0
—
5.74
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
0.32
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
11.17
—
0
6
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
72.78
—
0
6
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
7.8
—
10.16
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
-0.00
1.2
1.2
9.53
22.69
u/l
—
5
49
Mortality – FinRegistry
↥Association
Association between endpoint H8_POSTOP and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_POSTOP | 1.144 [0.98, 1.33] | 0.082 |
| Birth year | 0.996 [0.99, 1.0] | 0.295 |
During the follow-up period (1.1.1998 — 31.12.2019), 277 out of 1246 females with H8_POSTOP died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_POSTOP | 1.039 [0.89, 1.21] | 0.623 |
| Birth year | 0.989 [0.98, 1.0] | 0.021 |
During the follow-up period (1.1.1998 — 31.12.2019), 310 out of 1325 males with H8_POSTOP died.
Mortality risk
Mortality risk for people of age
years, who have H8_POSTOP.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.115% | 0.218% |
| 5 | 0.677% | 1.277% |
| 10 | 1.588% | 3.284% |
| 15 | 3.028% | 6.119% |
| 20 | 5.623% | 10.166% |
Relationships between endpoints
↥Index endpoint: H8_POSTOP – Postprocedural disorders of ear and mastoid process, not elsewhere classified
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data