Benign neoplasm: Rectosigmoid junction

CD2_BENIGN_RECTOSIGMOID_JUNC

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D12.7&
  • Cause of death: ICD-10 D12.7&

2 out of 7 registries used, show all original rules.

1702

4. Check minimum number of events

None

1702

5. Include endpoints

None

1702

6. Filter based on genotype QC (FinnGen only)

1529

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D12
Name in latin
Neoplasma benignum junctionis rectosigmoideae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7788 3752 4004
Only index persons 7330 3571 3759
Unadjusted period prevalence (%)
Whole population 0.11 0.11 0.11
Only index persons 0.14 0.13 0.14
Median age at first event (years)
Whole population 67.02 67.20 66.82
Only index persons 66.65 66.81 66.51

-FinnGen-

Key figures

All Female Male
Number of individuals 1529 737 792
Unadjusted period prevalence (%) 0.31 0.26 0.36
Median age at first event (years) 66.44 65.51 67.30

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1585
Matched controls
15850
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
13.0
307.7
547
618
D12.7
ICD-10 Finland
Benign neoplasm: Rectosigmoid junction
4503599627370496.0
307.7
1582
5
UJF32
NOMESCO Finland
Coloscopy
10.1
307.7
1140
3204
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
10.2
266.4
335
405
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
7.7
263.9
451
783
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
9.7
232.3
300
373
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
6.5
162.2
298
542
UJF30
NOMESCO Finland
Ileoscopy through colon
4.6
131.9
384
1036
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
3.7
129.1
612
2326
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
10.2
115.1
134
142
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
6.7
109.3
186
309
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
7.9
97.8
140
192
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
8.8
93.4
121
147
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
6.7
87.2
145
234
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.6
74.0
700
3681
K63.5
ICD-10 Finland
Polyp of colon
5.6
50.0
97
181
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
43.5
651
3939
JGA05
NOMESCO Finland
Endoscopic polypectomy in rectum
12.5
38.5
38
31
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
3.3
36.3
148
483
A06AC01
ATC
ispaghula (psylla seeds); oral
2.0
36.1
533
3161
D12.9
ICD-10 Finland
Benign neoplasm: Anus and anal canal
9.0
34.7
43
49
JFB47
NOMESCO Finland
Laparoscopic resection of sigmoid colon
6.7
33.3
53
81
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.6
32.0
200
824
JF2BD
NOMESCO Finland
Extensive colon CT
8.4
28.3
37
45
JFA45
NOMESCO Finland
Endoscopic contact coagulation in colon
10.2
27.4
31
31
D37.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Colon
5.1
27.2
57
114
D37.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Rectum
7.0
26.4
40
58
D06
ICPC
Abdominal pain localized other
2.5
26.3
177
754
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
25.9
466
2894
JN4BD
NOMESCO Finland
Extensive body CT
2.2
25.9
233
1128
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
2.7
24.9
139
539
A02BC02
ATC
pantoprazole; systemic
1.8
24.7
1163
9503
K92.1
ICD-10 Finland
Melaena
2.7
24.5
136
526
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.2
23.2
217
1066
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.3
22.7
180
825
D64.9
ICD-10 Finland
Anaemia, unspecified
2.1
22.4
247
1292
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.4
21.8
155
676
R02
ICPC
Shortness of breath/dyspnoea
2.0
21.3
272
1498
C18.72
ICD-10 Finland
Malignant tumor of sigmoid carcinoma of adenoma
9.1
21.2
26
29
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
3.6
21.2
71
204
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
21.0
339
2016
P01AB01
ATC
metronidazole; oral, rectal
1.7
21.0
636
4529
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.2
20.8
196
964
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.7
20.6
115
446
WX002
NOMESCO Finland
Sedation and analgesia
1.8
18.9
357
2220
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
2.7
18.9
101
383
8140/3-C18.7
ICD-O-3
Adenocarcinoma, NOS, of sigmoid colon
4.7
18.7
43
93
Z2221
NOMESCO Finland
Medical doctor
1.7
18.4
440
2923
UJF34
NOMESCO Finland
Left colonoscopy
7.9
18.3
25
32
R4110
NOMESCO Finland
Physiotherapy
1.7
17.9
480
3280
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
17.9
855
6722
UJH02
NOMESCO Finland
Anoscopy
2.8
17.7
90
332
B01AB05
ATC
enoxaparin; parenteral
1.6
17.6
557
3965
UJG02
NOMESCO Finland
Proctoscopy
3.6
17.5
57
161
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
17.3
399
2619
ZXE00
NOMESCO Finland
One hour or less
1.6
17.0
611
4479
C18.70
ICD-10 Finland
Malignant tumor of the sigmoid without histology
4.6
16.9
40
89
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
4.3
16.5
43
103
K62.1
ICD-10 Finland
Rectal polyp
5.0
16.4
35
71
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
16.4
245
1415
WX402
NOMESCO Finland
General anaesthesia
1.7
16.1
360
2338
XF402
NOMESCO Finland
ECG with work load test
1.9
15.7
211
1176
Z12.1
ICD-10 Finland
Special screening examination for neoplasm of intestinal tract
4.2
15.4
40
96
D01
ICPC
Abdominal pain/cramps general
1.9
15.1
196
1078
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.8
14.7
74
272
TPH07
NOMESCO Finland
Cathetrisation of artery
1.8
14.5
218
1258
J01DB01
ATC
cefalexin; oral
1.7
14.5
1269
11199
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
14.5
377
2537
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.7
14.2
297
1888
N02BE01
ATC
paracetamol; systemic, rectal
1.9
14.1
1420
12961
JFA85
NOMESCO Finland
Endoscopic mucosal or submucosal resection in colon
15.9
13.9
22
14
WX704
NOMESCO Finland
Intubation
2.1
13.9
143
725
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
13.8
493
3571
JFB31
NOMESCO Finland
Laparoscopic right hemicolectomy
3.9
13.6
40
105
A02BC05
ATC
esomeprazole; systemic
1.5
13.6
645
4959
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
3.3
13.3
49
150
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.0
13.2
160
859
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
3.1
13.2
56
187
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
12.9
208
1225
JFB46
NOMESCO Finland
Resection of sigmoid colon
4.2
12.7
33
79
N03AX16
ATC
[U] pregabalin
1.6
12.3
378
2632
JFA52
NOMESCO Finland
Other endoscopic haemostatic procedure in colon
9.7
12.2
24
25
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
12.1
304
2017
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
12.0
409
2913
R06.0
ICD-10 Finland
Dyspnoea
1.5
11.9
467
3428
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
11.7
584
4500
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.4
11.6
78
331
R03AC02
ATC
salbutamol; inhalant
1.4
11.4
805
6611
N02AX02
ATC
tramadol; systemic, rectal
1.4
11.3
698
5588
JGB04
NOMESCO Finland
Laparoscopic partial proctectomy with partial excision of mesorectum
15.2
11.3
18
12
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
2.7
11.3
58
216
D16
ICPC
Rectal bleeding
2.9
11.0
52
185
L05
ICPC
Flank/axilla symptom/complaint
2.0
10.9
120
624
K59.09
ICD-10 Finland
Constipation, unspecified
1.9
10.8
132
710
K57.2
ICD-10 Finland
Diverticular disease of large intestine with perforation and abscess
3.1
10.6
43
140
Z3226
NOMESCO Finland
Physiotherapist
1.6
10.5
284
1913
D18
ICPC
Change in faeces/bowel movements
2.7
10.4
54
202
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
2.9
10.4
47
163
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
10.4
559
4344
WX290
NOMESCO Finland
Other blockage of nerve
1.4
10.2
608
4812
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
10.1
1044
9095
C05AA08
ATC
fluocortolone; rectal, topical
1.7
10.0
214
1361
JN4AD
NOMESCO Finland
Body CT examination
1.7
9.9
212
1348
J01AA02
ATC
doxycycline; systemic
1.5
9.9
1198
10728
J01CA04
ATC
amoxicillin; systemic
1.5
9.8
1194
10687
R53
ICD-10 Finland
Malaise and fatigue
1.5
9.8
381
2775
WX702
NOMESCO Finland
Supraglottic ventilation device
2.1
9.8
95
471
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.0
9.8
114
604
H02AB06
ATC
prednisolone; systemic
1.4
9.6
736
6068
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
2.4
9.6
64
272
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.7
9.5
183
1130
JGA85
NOMESCO Finland
Endoscopic mucosal or submucosal resection in rectum
15.1
9.5
15
10
SPAT1263
SPAT
Sampling
1.4
9.5
608
4857
B82
ICPC
Anaemia other/unspecified
2.4
9.5
63
267
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
9.4
640
5161
C20.92
ICD-10 Finland
Malignant tumor of the rectum carcinoma of the adenoma
5.2
9.4
19
37
J01MA12
ATC
levofloxacin; systemic
1.5
9.2
302
2122
G47.3
ICD-10 Finland
Sleep apnoea
1.5
9.1
355
2584
D11
ICPC
Diarrhoea
1.7
9.1
158
950
S18
ICPC
Laceration/cut
1.4
9.0
761
6349
M79.6
ICD-10 Finland
Pain in limb
1.4
8.9
659
5377
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
8.9
733
6089
8140/3-C19.9
ICD-O-3
Adenocarcinoma, NOS, of rectosigmoid junction
8.7
8.8
18
21
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
8.8
281
1961
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.9
8.8
109
591
K59.1
ICD-10 Finland
Functional diarrhoea
2.0
8.7
94
485
C19
ICD-10 Finland
Malignant neoplasm of rectosigmoid junction
6.6
8.7
21
32
L17
ICPC
Foot/toe symptom/complaint
1.4
8.6
474
3673
Z3231
NOMESCO Finland
Registered nurse
1.4
8.6
408
3078
J01MA02
ATC
ciprofloxacin; systemic
1.4
8.6
609
4929
TJG20
NOMESCO Finland
Transanal irrigation
16.4
8.6
13
8
C03DA01
ATC
spironolactone; oral
1.6
8.5
219
1454
L01BC06
ATC
capecitabine; oral
2.2
8.5
72
339
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
8.4
200
1305
C199, 8148, 2
ICD-O-3
+∞
8.3
8
*
K85
ICPC
Elevated blood pressure
1.5
8.3
296
2113
A01
ICPC
Pain general/multiple sites
1.7
8.3
166
1037
R03BB04
ATC
tiotropium bromide; inhalant
1.6
8.2
176
1117
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
8.2
319
2314
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
8.2
148
898
H02AB07
ATC
prednisone; oral
1.6
8.2
208
1379
Z71.8
ICD-10 Finland
Other specified counselling
1.4
8.0
465
3627
A02BA02
ATC
ranitidine; systemic
1.5
8.0
306
2212
ZX120
NOMESCO Finland
Intravenous
1.7
8.0
150
920
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
3.1
8.0
32
104
C08CA01
ATC
amlodipine; oral
1.4
8.0
665
5502
T90
ICPC
Diabetes non-insulin dependent
1.4
8.0
417
3196
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
8.0
132
782
I50.9
ICD-10 Finland
Heart failure, unspecified
1.5
7.9
261
1830
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.9
7.9
92
489
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.1
7.9
69
330
UJD02
NOMESCO Finland
Gastroscopy
2.0
7.8
82
419
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
7.8
114
651
J01DA01
ATC
[U] cefalexin
1.4
7.8
897
7785
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.7
7.8
157
982
ZXE20
NOMESCO Finland
More than three and less than five hours
1.6
7.8
215
1452
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.6
7.8
176
1134
C07AB07
ATC
bisoprolol; oral
1.3
7.7
827
7094
JFG10
NOMESCO Finland
Closure of loop colostomy without resection
3.9
7.7
22
57
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.4
7.7
411
3160
H01
ICPC
Ear pain/earache
1.7
7.7
150
931
C03CA01
ATC
furosemide; systemic
1.4
7.6
534
4291
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
2.6
7.6
43
169
JFA55
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in colon
6.7
7.6
18
27
M54.5
ICD-10 Finland
Low back pain
1.4
7.6
515
4118
JFF23
NOMESCO Finland
Transversostomy
3.5
7.6
25
72
K29.9
ICD-10 Finland
Gastroduodenitis, unspecified
4.1
7.5
20
49
PEF23
NOMESCO Finland
Thrombendarterectomy of femoral artery
2.8
7.5
36
130
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
7.5
206
1390
XF404
NOMESCO Finland
Ambulatory ECG
1.7
7.3
145
902
WX320
NOMESCO Finland
Spinalanesthesy
1.4
7.3
390
2992
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
7.3
425
3309
D15
ICPC
Melaena
6.9
7.3
17
25
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.7
7.3
141
873
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
7.3
401
3096
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
1.9
7.2
83
440
J02AC01
ATC
fluconazole; systemic
1.4
7.1
492
3936
8263/2-C18.7
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of sigmoid colon
20.1
7.1
10
5
R39.1
ICD-10 Finland
Other difficulties with micturition
2.2
7.1
55
250
WX722
NOMESCO Finland
PEEP
1.9
7.1
81
427
L03
ICPC
Low back symptom/complaint
1.4
7.1
412
3206
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
7.1
278
2018
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.8
7.1
107
618
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
7.1
496
3979
A29
ICPC
General symptom/complaint other
1.5
7.0
221
1534
D50.8
ICD-10 Finland
Other iron deficiency anaemias
3.2
7.0
27
86
A11
ICPC
Chest pain NOS
1.6
7.0
147
930
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
7.0
1034
9243
K55.2
ICD-10 Finland
Angiodysplasia of colon
4.4
7.0
17
39
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.0
6.9
75
389
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.1
6.8
63
308
D13.2
ICD-10 Finland
Benign neoplasm: Duodenum
4.1
6.8
18
44
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
6.8
551
4510
WX892
NOMESCO Finland
Monitored bed care
1.7
6.8
126
772
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
6.8
424
3337
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.4
6.8
380
2938
XG405
NOMESCO Finland
Education on PEF monitoring
3.1
6.8
27
88
C187, 8148, 2
ICD-O-3
16.8
6.7
10
6
K64.1
ICD-10 Finland
Second degree haemorrhoids
2.6
6.7
38
150
K31.8
ICD-10 Finland
Other specified diseases of stomach and duodenum
5.9
6.6
17
29
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
6.5
225
1590
ZXA10
NOMESCO Finland
Bilateral
1.4
6.5
278
2047
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.5
6.5
183
1239
K29.7
ICD-10 Finland
Gastritis, unspecified
2.1
6.5
57
273
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
6.5
755
6492
I20.99
ICD-10 Finland
Angina pectoris, unspecified
1.7
6.5
114
688
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.4
6.5
394
3083
C10AA05
ATC
atorvastatin; oral
1.3
6.5
711
6066
A02BC01
ATC
omeprazole; systemic
1.4
6.4
401
3151
TJX00
NOMESCO Finland
Punkture or biopsy in gastrointestinal endoscopy
14.4
6.4
10
7
P01
ICPC
Feeling anxious/nervous/tense
1.8
6.4
100
584
Z25.1
ICD-10 Finland
Need for immunization against influenza
1.9
6.4
79
429
G44.2
ICD-10 Finland
Tension-type headache
1.5
6.4
176
1188
N06AA09
ATC
amitriptyline; systemic
1.6
6.4
146
944
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.8
6.3
97
563
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
6.3
433
3450
N02BF02
ATC
pregabalin; oral
1.8
6.3
100
586
R01AD09
ATC
mometasone; nasal
1.3
6.3
584
4861
S17
ICPC
Abrasion/scratch/blister
2.5
6.3
38
155
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.5
6.3
215
1517
JN4CD
NOMESCO Finland
Very extensive body CT
2.0
6.3
63
318
SPAT1294
SPAT
Other function in accordance with health social work nomenclature
2.4
6.3
42
180
XG466
NOMESCO Finland
Sleep oxymetry
2.2
6.2
49
225
K64.0
ICD-10 Finland
First degree haemorrhoids
2.4
6.2
40
168
S16
ICPC
Bruise/contusion
2.2
6.2
52
245
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
2.5
6.2
37
150
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.5
6.2
194
1345
SPAT1097
SPAT
Recording of ECG
1.5
6.2
230
1651
PEN23
NOMESCO Finland
Plastic repair of femoral artery
3.5
6.2
20
57
R60.0
ICD-10 Finland
Localized oedema
1.5
6.2
205
1439
JGB00
NOMESCO Finland
Partial proctectomy and colorectal or coloanal anastomosis
5.8
6.1
16
28
K59.0
ICD-10 Finland
Constipation
1.8
6.1
91
523
L14
ICPC
Leg/thigh symptom/complaint
1.6
6.1
126
794
UKC02
NOMESCO Finland
Cystoscopy
1.4
6.1
264
1949
G04CA02
ATC
tamsulosin; oral
1.4
6.1
407
3228
M54.8
ICD-10 Finland
Other dorsalgia
2.0
6.1
63
322
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
3.0
6.1
25
83
N05AA02
ATC
levomepromazine; systemic
2.1
6.1
57
281
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.6
6.1
155
1028
UJF92
NOMESCO Finland
Capsular endoscopy
2.5
6.0
35
140
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.4
6.0
299
2260
SPAT1211
SPAT
Application of soft bandage
1.6
6.0
130
828
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
6.0
250
1831
C18.21
ICD-10 Finland
Malignant tumor of the ascending colon invasive carcinoma
3.3
6.0
22
68

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
653
1679
5.91
254.02
1.6
1.3
—
—
—
0
0
418
1779
2.83
66.23
5.0
4.2
9.37
19.85
ug/l
1.15
338
1472
828
5666
1.97
37.47
2.8
2.3
—
—
—
0
0
656
4150
1.99
37.27
2.8
2.3
3.05
2.94
mg/l
0.41
579
3567
944
6790
1.97
36.50
7.0
6.6
2.74
2.86
%
0.91
883
6352
944
6802
1.96
36.16
7.1
6.7
9.23
9.08
%
0.70
889
6361
942
6788
1.96
36.02
7.1
6.7
0.68
0.68
%
0.02
884
6344
207
821
2.75
35.91
2.8
2.4
—
—
—
0
0
457
2576
2.09
35.47
2.7
2.7
2.36
2.27
g/l
2.33
433
2392
715
4744
1.92
34.56
3.7
3.3
29.69
34.33
u/l
2.85
678
4471
933
6758
1.93
34.47
6.9
6.5
58.20
58.07
%
0.13
886
6450
959
7049
1.91
33.43
6.1
5.3
35.24
35.09
g/l
0.35
908
6617
392
2128
2.12
33.33
1.4
1.3
—
—
—
0
0
425
2402
2.05
32.30
2.7
2.7
20.35
22.33
%
2.17
403
2243
938
6906
1.88
31.84
7.2
6.6
26.46
26.51
%
0.05
893
6538
466
2747
1.99
31.32
2.8
2.7
11.86
12.50
umol/l
1.01
443
2561
1054
8097
1.90
30.84
7.8
6.9
11.49
11.87
umol/l
0.42
1014
7725
1337
11171
2.26
30.73
10.7
8.8
80.59
80.69
u/l
0.03
1297
10601
327
1723
2.13
29.68
2.7
2.8
7.42
8.20
umol/l
0.37
279
1543
868
6375
1.80
28.27
3.7
3.1
125.47
147.35
ug/l
1.85
824
5879
299
1574
2.11
26.98
2.3
2.3
151.67
142.43
ug/g
0.11
251
1270
966
7382
1.79
26.91
6.9
6.3
0.04
0.04
e9/l
0.22
835
6264
1023
7952
1.81
26.89
8.6
7.7
1.21
1.21
mmol/l
0.51
915
6858
963
7363
1.78
26.67
6.9
6.3
0.64
0.61
e9/l
3.16
833
6248
986
7596
1.79
26.55
7.1
6.5
0.19
0.20
e9/l
0.14
858
6558
972
7490
1.77
25.80
7.0
6.4
1.87
1.90
e9/l
0.19
850
6525
975
7522
1.77
25.75
18.4
17.4
1.29
1.30
inr
0.36
838
6313
1050
8280
1.79
25.68
10.3
9.9
4.26
4.20
e9/l
0.33
908
7161
692
4859
1.75
25.37
3.0
2.7
66.46
77.77
u/l
0.27
658
4495
1257
10529
1.94
24.68
5.4
4.6
13.93
13.55
mm/h
0.37
1198
9796
1090
8770
1.78
23.99
4.2
3.4
54.68
54.97
u/l
0.03
1042
8151
917
7033
1.72
23.92
2.6
2.2
95.64
95.24
pmol/l
0.08
498
3774
927
7196
1.69
22.51
7.9
6.9
1.21
1.21
mmol/l
1.14
871
6635
685
4919
1.69
22.27
2.7
2.7
—
—
—
0
0
1095
8923
1.73
21.91
6.7
5.4
6.94
6.83
mmol/l
0.75
1060
8562
563
3854
1.71
21.73
5.5
4.3
86.66
86.68
%
0.01
551
3781
1466
13316
2.34
18.35
25.7
18.6
26.04
26.19
mg/l
0.06
1312
11209
1130
9539
1.64
17.20
5.8
5.1
142.93
1766.65
e6/l
2.40
15
150
387
2544
1.69
16.56
4.0
3.2
2.11
2.09
e6/l
0.01
216
1284
455
3120
1.64
16.54
4.8
4.2
383.41
344.55
ng/l
0.08
372
2616
862
6867
1.56
16.44
3.1
2.9
—
—
estimate
—
0
0
446
3074
1.63
15.75
3.3
3.0
516.85
530.06
mosm/kgh2o
0.65
387
2679
734
5679
1.54
15.70
5.0
4.1
69.67
110.82
e6/l
0.99
527
4133
248
1456
1.83
15.67
2.7
2.4
35.07
37.84
u/l
0.48
204
1227
633
4775
1.54
14.98
1.8
1.8
19.88
20.15
nmol/l
0.18
546
4001
668
5119
1.53
14.59
4.3
3.5
42.02
87.22
e6/l
1.68
521
3976
587
4404
1.53
14.00
4.3
3.4
0.38
0.47
e6/l
0.70
447
3295
400
2761
1.60
13.76
4.0
3.1
1.05
1.13
e6/l
0.19
231
1510
133
659
2.11
13.71
3.5
3.4
5078.35
6239.53
u/ml
0.07
110
572
513
3755
1.54
13.62
2.8
2.6
—
—
—
0
0
303
1970
1.67
13.20
1.3
1.3
—
—
—
0
0
142
732
2.03
13.16
2.1
2.7
3.70
3.73
g/l
0.09
127
671
311
2037
1.66
13.16
3.0
2.7
1.85
1.81
%
0.26
279
1825
142
733
2.03
13.11
2.1
2.6
7.24
7.42
g/l
0.66
127
671
142
733
2.03
13.11
2.1
2.6
4.22
4.19
g/l
0.16
127
672
680
5320
1.49
12.97
3.6
3.3
2017.95
1438.09
ng/l
1.32
605
4638
126
631
2.08
12.63
2.1
2.8
10.60
10.52
g/l
0.07
110
565
134
688
2.04
12.56
2.2
2.7
2.83
2.97
g/l
0.82
119
627
154
835
1.94
12.36
1.7
1.8
1.69
1.57
g/l
0.82
133
728
1368
12463
1.71
12.11
6.3
5.4
1.96
1.99
mu/l
0.42
1287
11383
1185
10442
1.53
11.99
4.7
4.3
14.99
14.99
pmol/l
0.02
1100
9485
285
1868
1.64
11.93
1.4
1.3
666.43
508.95
titre
0.49
56
427
432
3126
1.53
11.79
1.8
1.7
1.42
1.38
mg/l
0.08
353
2476
621
4848
1.46
11.60
5.3
4.4
7.40
7.40
ph
0.24
458
3547
1485
13905
2.08
11.57
30.6
22.6
139.70
139.64
mmol/l
0.32
1470
13647
388
2754
1.54
11.54
3.9
3.3
0.80
0.82
mmol/l
1.29
367
2600
237
1494
1.69
11.50
2.8
3.0
66.01
66.32
g/l
0.26
210
1375
513
3865
1.48
11.46
3.5
3.2
0.00
0.02
—
10
97
372
2622
1.55
11.40
1.5
1.5
2.70
2.60
g/l
0.34
211
1569
202
1226
1.74
11.24
2.3
2.8
—
—
—
0
0
1485
13928
2.05
11.15
31.0
22.9
3.98
4.00
mmol/l
1.13
1470
13654
682
5455
1.44
11.03
4.4
3.6
2.36
2.35
mmol/l
0.27
621
4934
401
2891
1.52
11.02
1.9
1.8
1007.01
1183.44
nmol/l
3.68
313
2179
575
4460
1.45
10.94
7.6
6.6
—
—
—
0
0
594
4670
1.43
10.38
5.0
4.5
—
—
—
0
0
297
2030
1.57
10.33
8.2
7.9
7.42
7.42
ph
0.06
153
1132
796
6600
1.41
10.28
2.7
2.5
76.81
78.91
nmol/l
1.34
730
5888
245
1602
1.63
10.26
2.7
2.2
0.21
0.21
g/l
0.99
232
1490
273
1836
1.59
10.17
8.2
8.1
95.28
95.32
%
0.03
267
1778
682
5512
1.42
10.15
4.6
4.2
10.26
8.68
mg/mmol
0.38
452
3471
1487
14011
1.99
10.11
16.8
13.3
25.09
25.52
u/l
0.54
1457
13580
295
2026
1.56
10.02
8.2
7.8
0.75
0.95
mmol/l
0.39
249
1685
398
2917
1.49
9.96
1.3
1.3
2.91
1.47
u/ml
0.57
80
782
136
762
1.86
9.87
3.9
4.0
—
—
—
0
0
475
3610
1.45
9.85
2.9
2.7
4.56
5.34
e6/l
0.80
423
3298
296
2042
1.55
9.85
8.2
7.8
5.08
5.11
kpa
0.22
287
1967
1418
13196
1.71
9.70
6.6
5.7
6.16
6.06
mmol/l
2.08
1334
11988
295
2043
1.55
9.63
8.2
7.8
11.99
11.92
kpa
0.10
284
1973
1498
14185
2.02
9.50
33.9
24.9
83.75
81.40
umol/l
1.19
1486
14024
173
1054
1.72
9.46
10.0
9.8
24.30
24.32
mmol/l
0.03
168
1038
89
437
2.10
9.43
3.9
3.4
2.09
1.98
index
0.06
54
233
735
6072
1.39
9.38
4.8
4.2
42.72
68.96
ng/l
0.99
567
4680
176
1085
1.70
9.22
3.9
3.9
7.41
7.42
ph
0.31
148
914
234
1553
1.59
9.17
8.6
7.7
1.29
1.35
mmol/l
0.51
226
1528
673
5504
1.39
9.00
3.8
3.5
7.42
7.33
mmol/l
0.20
576
4624
212
1383
1.62
8.91
1.4
1.4
—
—
—
0
0
661
5399
1.38
8.87
3.7
3.5
49.96
47.77
mg/l
0.11
443
3500
601
4834
1.39
8.84
3.5
3.4
—
—
—
0
0
178
1113
1.68
8.84
3.9
3.9
5.12
5.19
kpa
0.59
168
1075
225
1495
1.59
8.76
10.1
8.9
—
—
—
0
0
108
584
1.91
8.75
3.5
4.1
24.47
25.10
mmol/l
1.34
95
538
91
464
2.02
8.73
1.5
1.6
15.82
19.28
u/ml
0.21
15
90
90
461
2.01
8.53
1.3
1.5
315.30
270.93
ug/g
1.14
55
288
1390
12953
1.59
8.45
8.6
7.1
40.47
40.14
mmol/mol
0.69
1310
12022
317
2291
1.48
8.35
2.1
2.1
—
—
—
0
0
1438
13528
1.68
8.22
21.3
16.8
—
—
—
0
0
749
6297
1.36
8.17
14.5
12.5
0.00
0.00
e9/l
0.15
608
5135
1499
14297
1.89
7.77
38.8
28.3
7.00
6.81
e9/l
2.55
1475
13936
722
6072
1.35
7.70
3.8
3.7
6.12
6.26
ph
3.08
397
3341
1498
14293
1.88
7.63
38.7
28.2
91.53
91.68
fl
0.57
1485
14118
1498
14294
1.87
7.61
38.9
28.3
246.42
244.33
e9/l
0.57
1477
13986
1498
14295
1.87
7.60
38.8
28.3
4.39
4.43
e12/l
2.17
1476
13936
1498
14295
1.87
7.60
39.7
28.9
39.63
39.98
%
1.79
1484
14111
1498
14297
1.87
7.56
39.0
28.5
131.75
133.79
g/l
5.54
1485
14123
129
771
1.73
7.56
4.1
3.8
1.02
1.02
ratio
0.90
111
710
228
1569
1.53
7.56
8.0
7.2
11.52
10.59
mmol/l
0.45
216
1507
231
1597
1.52
7.50
2.6
2.8
72.13
69.11
e9/l
0.67
163
1197
309
2266
1.45
7.48
7.0
5.8
1.04
1.03
mmol/l
0.20
294
2098
1497
14294
1.85
7.41
38.6
28.2
30.31
30.45
pg
2.20
1484
14119
149
933
1.66
7.36
1.2
1.3
—
—
—
0
0
506
4059
1.36
7.23
3.0
3.0
358.35
351.28
umol/l
0.81
443
3538
202
1368
1.55
7.20
2.9
3.2
220.64
224.08
ng/l
0.04
188
1265
146
919
1.65
7.07
2.6
2.5
19.71
19.03
au/ml
0.04
15
70
219
1521
1.51
6.94
3.8
4.5
7.38
7.36
ph
1.77
174
1096
134
832
1.67
6.84
1.4
1.3
34.33
54.60
au/ml
—
9
67
600
4972
1.33
6.82
2.3
2.3
185.86
219.70
u/l
0.55
565
4716
157
1016
1.61
6.80
1.2
1.2
—
—
—
0
0
123
749
1.70
6.76
1.8
2.0
—
—
—
0
0
333
2518
1.41
6.75
1.4
1.3
42.61
33.72
iu/ml
0.35
98
804
98
566
1.78
6.50
3.4
3.1
289.93
287.03
mg/l
0.01
46
236
1393
13143
1.49
6.30
6.0
5.4
1.43
1.45
mmol/l
1.46
1307
12032
1421
13479
1.52
6.08
7.1
6.4
2.54
2.60
mmol/l
1.55
1342
12390
186
1288
1.50
5.97
4.2
3.9
96.76
94.15
ng/l
0.15
161
1109
70
374
1.91
5.96
3.9
3.5
124.58
1070.71
u/ml
0.78
59
350
96
566
1.74
5.95
1.2
1.2
—
—
—
0
0
157
1054
1.54
5.82
10.3
8.5
25.02
24.88
mmol/l
0.18
157
1049
1396
13226
1.47
5.68
6.1
5.5
4.46
4.52
mmol/l
1.29
1309
12214
864
7651
1.28
5.61
4.4
4.2
0.00
3.16
estimate
1.08
171
1666
44
204
2.19
5.50
1.8
2.4
1.10
1.08
g/24h
0.02
27
120
139
924
1.55
5.39
2.0
1.9
1.47
1.46
g/l
0.02
129
846
50
247
2.06
5.33
1.3
1.2
—
—
—
0
0
852
7560
1.27
5.32
4.4
4.1
0.01
0.00
estimate
0.50
170
1624
408
3301
1.32
5.22
4.0
3.1
2.47
2.46
mmol/l
0.48
364
2988
864
7701
1.27
5.11
4.5
4.2
0.05
0.21
estimate
0.38
165
1549
202
1469
1.43
5.04
2.3
2.1
0.03
0.01
estimate
0.25
35
280
14
29
4.86
4.81
1.0
1.1
—
—
—
0
0
67
380
1.80
4.79
4.4
5.0
—
—
—
0
0
1333
12619
1.35
4.62
5.1
4.6
1.34
1.30
mmol/l
1.51
1239
11438
1165
10833
1.28
4.56
33.7
23.2
14.05
13.81
%
6.37
1160
10686
230
1741
1.38
4.55
4.6
3.6
7.38
7.38
ph
0.29
132
1005
453
3782
1.28
4.47
1.4
1.3
—
—
—
0
0
240
1836
1.36
4.44
1.4
1.5
—
—
—
0
0
18
60
3.02
4.40
3.8
2.3
0.61
0.61
mmol/l
0.01
18
60
234
1794
1.36
4.27
1.9
1.8
—
—
—
0
0
160
1154
1.43
4.19
2.8
3.1
11.03
10.85
g/l
0.18
152
1062
69
412
1.71
4.17
1.3
1.7
—
—
—
0
0
99
649
1.56
4.13
3.3
3.9
46.30
85.55
mg/l
0.87
87
557
99
650
1.56
4.11
3.3
3.9
65.23
59.81
mg/l
0.13
87
556
82
517
1.62
4.04
2.0
1.9
20.54
21.13
s
0.71
74
470
174
1284
1.40
4.01
1.8
1.6
—
—
—
0
0
293
2342
1.31
4.01
1.4
1.3
23.77
12.67
u/ml
1.03
86
842
45
242
1.88
3.86
1.8
1.8
218.13
271.70
mu/l
1.61
38
223
218
1679
1.35
3.86
4.9
3.6
1.87
1.92
mmol/l
0.06
203
1435
33
159
2.10
3.84
3.2
3.3
11.65
11.29
index
0.08
20
95
90
588
1.56
3.83
3.4
3.8
11.09
3.66
ratio
0.42
48
344
239
1881
1.32
3.65
5.8
5.3
32.17
32.82
%
0.48
180
1211
46
260
1.79
3.41
1.4
1.3
12.84
9.69
u/l
0.57
33
206
665
5927
1.21
3.40
2.1
2.0
1.38
1.34
mmol/l
0.70
556
4896
176
1339
1.35
3.39
2.5
2.5
0.40
0.48
e6/l
0.25
170
1278
31
155
2.02
3.31
1.2
1.2
—
—
—
0
0
186
1433
1.34
3.30
1.8
1.5
—
—
—
0
0
207
1620
1.32
3.29
1.7
1.6
—
—
—
0
0
159
1197
1.36
3.28
2.7
2.4
13.40
13.11
nmol/l
0.17
136
1066
41
227
1.83
3.26
1.3
1.7
0.83
0.84
g/l
0.02
30
180
627
5582
1.20
3.19
6.5
5.9
2.12
2.95
ug/l
2.67
565
5019
27
130
2.10
3.19
1.1
1.3
0.42
0.42
g/l
0.04
21
94
27
130
2.10
3.19
1.1
1.3
8.12
7.13
g/l
0.33
21
94
27
130
2.10
3.19
1.1
1.3
2.74
3.00
g/l
0.37
22
94
220
1746
1.30
3.16
4.8
3.6
5.84
5.83
kpa
0.10
214
1692
98
682
1.47
3.15
1.3
1.2
—
—
—
0
0
37
202
1.85
3.09
1.2
1.1
—
—
—
0
0
63
400
1.60
3.08
1.3
1.2
92.86
105.53
titre
—
7
38
27
132
2.06
3.07
1.1
1.3
—
—
—
0
0
233
1877
1.28
2.99
3.8
3.3
4.42
4.95
e9/l
0.70
199
1597
73
484
1.53
2.98
5.0
6.2
1.11
1.35
mmol/l
3.17
68
424
79
535
1.50
2.93
1.9
1.7
0.50
0.37
mg/l
0.66
36
245
1128
10644
1.21
2.90
34.1
24.6
330.74
331.62
g/l
2.62
1123
10590
106
762
1.42
2.89
1.1
1.2
116.69
145.73
u/ml
0.30
37
278
97
688
1.44
2.85
2.5
2.8
—
—
—
0
0
24
117
2.07
2.78
1.1
1.1
—
—
—
0
0
23
111
2.09
2.73
1.2
1.2
382.60
376.05
nmol/l
0.04
15
93
31
167
1.87
2.72
1.2
1.2
0.18
0.19
nmol/l
0.32
20
132
35
197
1.79
2.69
1.1
1.1
17.55
20.34
au/ml
—
6
37
54
345
1.59
2.62
4.2
3.4
7.06
7.59
mmol/l
1.23
54
334
104
761
1.39
2.59
2.0
1.9
1.31
2.35
ug/l
0.68
93
678
30
163
1.86
2.58
1.2
1.2
—
—
nmol/l
—
0
0
22
107
2.07
2.57
2.7
1.6
17.12
2772.77
u/l
—
5
34
175
1387
1.29
2.57
2.3
2.3
398.14
379.46
nmol/l
0.57
161
1283
146
1133
1.32
2.50
3.5
2.8
5.98
6.05
ph
0.50
105
791
33
190
1.75
2.38
1.6
1.6
—
—
—
0
0
82
585
1.42
2.38
1.9
1.8
11.21
6.78
iu/ml
0.40
12
142
20
97
2.08
2.37
1.1
1.3
10.40
9.96
mmol/l
0.18
20
92
73
510
1.45
2.37
1.1
1.1
—
—
—
0
0
92
672
1.39
2.34
1.2
1.2
—
—
—
0
0
12
47
2.57
2.27
2.2
2.4
—
—
—
0
0
7
18
3.90
2.25
1.7
1.5
—
—
—
0
0
29
165
1.77
2.20
1.1
1.3
—
—
—
0
0
58
395
1.49
2.16
2.3
2.3
123.59
128.61
g/l
0.81
39
318
10
36
2.79
2.14
1.0
1.0
0.76
0.31
u/ml
—
5
8
32
190
1.70
2.11
2.6
2.6
—
—
—
0
0
57
391
1.47
2.06
1.4
1.2
23.78
2.59
u/ml
—
5
35
15
69
2.19
2.04
1.0
3.8
13235.30
58.31
mg/l
—
10
51
57
392
1.47
2.04
1.4
1.2
25.38
6.30
u/ml
—
9
55
6
15
4.01
2.04
1.7
1.3
79.50
36.93
umol/l
—
6
15
32
193
1.67
2.00
1.5
2.4
—
—
—
0
0
376
3321
1.17
1.96
3.9
3.4
0.92
0.78
ug/l
0.58
282
2286
178
1469
1.24
1.91
4.0
2.9
4.54
4.48
kpa
0.16
171
1423
55
382
1.46
1.89
1.2
1.1
—
—
—
0
0
50
341
1.48
1.88
1.6
1.3
56.29
58.64
mmol/l
0.19
38
276
19
100
1.91
1.85
1.3
1.2
—
—
—
0
0
16
79
2.04
1.85
3.1
2.2
15.49
17.49
nmol/l
0.56
16
73
5
12
4.18
1.82
1.0
1.2
—
—
—
0
0
59
419
1.42
1.82
4.2
3.2
1.49
1.59
mmol/l
0.58
59
407
20
108
1.86
1.82
1.2
1.4
—
63.64
—
0
11
45
303
1.50
1.81
1.3
1.5
0.98
0.89
nmol/l
0.40
39
248
26
153
1.71
1.80
2.0
2.3
—
—
—
0
0
97
751
1.31
1.76
2.1
2.2
0.00
1.21
estimate
0.50
20
208
40
265
1.52
1.74
1.4
1.5
33.30
31.66
g/l
0.29
33
241
30
186
1.62
1.73
3.6
1.5
—
—
—
0
0
30
186
1.62
1.73
3.6
1.4
—
—
—
0
0
19
103
1.85
1.72
1.2
1.4
7.31
7.41
ph
0.53
12
77
60
433
1.40
1.71
1.1
1.1
—
—
—
0
0
17
89
1.92
1.70
5.3
1.7
—
—
—
0
0
16
82
1.96
1.69
1.0
1.0
—
—
—
0
0
30
187
1.62
1.69
3.6
1.4
—
—
—
0
0
30
187
1.62
1.69
3.6
1.4
—
—
—
0
0
20
111
1.81
1.69
1.6
1.9
—
—
—
0
0
12
55
2.19
1.67
39.8
27.8
100.92
127.30
ug/l
1.09
12
43
24
142
1.70
1.65
3.8
1.5
—
—
—
0
0
115
920
1.27
1.64
3.5
2.6
0.65
0.62
%
0.24
115
914
17
303
0.56
1.64
1.1
1.2
1.42
1.55
g/l
1.62
17
303
47
327
1.45
1.64
2.0
1.9
2.66
22.98
iu/l
0.55
19
124
26
158
1.66
1.62
1.2
1.2
—
—
—
0
0
108
859
1.28
1.62
1.4
1.4
—
—
—
0
0
28
437
0.63
1.61
15.2
11.8
—
—
—
0
0
29
182
1.60
1.61
1.3
1.2
2.06
7.88
u/ml
1.54
16
89
26
159
1.65
1.59
1.2
1.1
—
—
—
0
0
28
175
1.61
1.58
3.8
1.5
—
—
—
0
0
6
20
3.01
1.58
1.3
1.4
57.17
63.45
ug/l
—
6
20
30
191
1.58
1.57
1.4
1.4
—
—
—
0
0
12
57
2.11
1.55
2.3
2.2
—
—
—
0
0
21
122
1.73
1.55
1.4
1.1
100.67
105.41
pmol/l
0.14
21
122
19
109
1.75
1.47
1.3
1.2
—
—
—
0
0
31
203
1.54
1.46
20.3
6.5
7.39
7.54
mmol/l
0.09
26
176
7
28
2.51
1.45
1.9
1.7
—
—
—
0
0
25
157
1.60
1.41
1.0
1.1
—
—
—
0
0
27
173
1.57
1.40
1.6
1.6
48.40
30.95
ng/l
0.38
27
173
21
126
1.68
1.40
5.0
1.8
—
—
—
0
0
372
3367
1.14
1.37
1.9
1.8
28155779.39
29909362.13
pmol/l
0.02
309
2745
114
935
1.24
1.35
3.5
2.6
1.27
1.16
%
0.60
114
926
32
216
1.49
1.33
1.1
1.1
—
—
—
0
0
21
128
1.65
1.33
3.2
3.3
21.39
30.54
mg/l
0.22
13
100
54
402
1.36
1.33
3.4
3.4
0.92
0.83
nmol/l
0.58
42
330
57
429
1.34
1.31
1.8
1.6
1.13
1.18
g/l
0.51
52
408
10
48
2.09
1.27
1.5
2.0
—
—
—
0
0
13
70
1.86
1.24
1.1
1.3
16.55
23.03
umol/l
0.52
13
61
170
1464
1.18
1.24
2.4
2.5
6.35
7.16
ug/l
0.42
145
1309
161
1383
1.18
1.21
4.3
4.8
0.68
0.11
%
0.39
37
373
21
132
1.60
1.20
2.4
2.3
—
—
—
0
0
29
198
1.47
1.17
1.4
1.4
79095.00
103999.02
e6/l
0.18
12
114
32
223
1.44
1.17
1.2
1.1
—
—
—
0
0
8
39
2.06
1.15
2.0
1.5
—
—
—
0
0
32
224
1.44
1.15
1.7
1.4
180.11
160.21
au/ml
—
9
63
28
191
1.47
1.14
1.3
1.5
7.00
6.52
mmol/l
0.43
22
183
93
764
1.23
1.12
3.4
3.4
4.46
4.43
pmol/l
0.09
82
673
26
176
1.49
1.10
1.3
1.6
63.79
63.60
%
0.01
14
115
8
41
1.96
1.09
5.1
3.1
9.88
5.46
ug/l
—
8
41
151
1305
1.17
1.07
5.3
3.9
1.23
1.22
mmol/l
0.21
132
1118
423
3914
1.11
1.07
4.1
3.7
0.00
0.04
estimate
1.17
123
1264
10
52
1.93
1.06
1.3
1.2
193.40
233.19
iu/ml
—
10
52
15
91
1.65
1.00
1.0
1.1
—
—
—
0
0
156
1362
1.16
0.99
4.2
4.4
0.51
0.71
%
0.64
41
431
51
397
1.29
0.98
1.2
1.2
—
—
—
0
0
0
29
0.00
0.97
0.0
1.4
—
—
—
0
0
55
435
1.27
0.95
1.4
1.7
12971.64
15472.74
e6/l
0.19
42
308
12
70
1.72
0.92
1.0
1.3
—
—
—
0
0
12
70
1.72
0.92
1.8
2.9
1843.33
1906.00
ml
0.09
12
60
28
201
1.40
0.91
1.5
1.5
—
—
—
0
0
28
201
1.40
0.91
1.5
1.5
—
—
—
0
0
28
201
1.40
0.91
1.5
1.5
—
—
—
0
0
28
201
1.40
0.91
1.5
1.5
—
—
—
0
0
52
411
1.27
0.91
2.0
2.2
12.11
12.25
mg/l
0.05
47
380
53
420
1.27
0.91
4.2
3.2
7.58
7.91
kpa
0.96
53
411
76
628
1.22
0.91
2.6
2.1
691.00
457.57
ug/l
0.19
76
599
18
118
1.53
0.91
1.1
1.2
—
—
—
0
0
23
325
0.70
0.90
1.6
1.2
0.99
0.90
g/l
0.59
23
325
31
228
1.37
0.89
1.8
2.6
—
—
—
0
0
26
186
1.40
0.87
1.5
1.2
—
—
—
0
0
12
72
1.67
0.85
2.3
2.4
215.80
962.09
e6/l
—
5
58
13
80
1.63
0.84
1.0
1.3
146.85
141.18
nmol/l
0.14
13
80
34
257
1.33
0.83
1.6
1.4
—
—
—
0
0
41
522
0.78
0.83
1.5
1.4
—
—
—
0
0
6
33
1.82
0.79
1.0
1.4
—
159.14
—
0
7
153
1361
1.14
0.78
4.4
4.6
0.19
0.11
%
0.52
32
391
23
165
1.40
0.78
1.3
1.3
35230.73
99264.15
e6/l
0.75
15
111
33
252
1.32
0.77
4.0
3.1
4.70
4.45
e9/l
0.18
33
252
9
53
1.70
0.75
1.2
1.4
—
—
—
0
0
439
4648
0.92
0.74
4.0
3.5
—
—
—
0
0
7
38
1.85
0.73
4.7
3.8
—
—
—
0
0
33
423
0.78
0.72
2.4
1.7
—
—
—
0
0
7
39
1.80
0.72
1.0
1.1
209.14
247.32
pmol/l
—
7
25
7
41
1.71
0.70
1.3
1.4
8.33
7.03
mmol/l
—
7
41
9
58
1.55
0.69
2.3
2.0
—
—
—
0
0
32
248
1.30
0.69
1.3
1.3
305.30
180.86
miu/ml
—
10
98
18
127
1.42
0.68
1.4
1.4
17.79
29.26
%
—
10
81
159
1436
1.12
0.66
4.3
4.5
1.07
0.92
%
0.18
38
464
16
111
1.45
0.66
1.1
1.1
—
—
—
0
0
58
686
0.84
0.63
1.9
1.8
3.42
3.43
mmol/l
0.02
36
506
39
315
1.24
0.62
3.7
3.0
59.97
59.26
%
0.10
39
315
30
235
1.28
0.61
1.5
1.4
792.06
5274.86
e6/l
0.66
17
168
39
317
1.24
0.60
1.5
1.2
—
—
—
0
0
21
157
1.34
0.59
1.5
1.3
—
—
—
0
0
0
23
0.00
0.58
0.0
2.3
—
0.11
—
0
6
6
35
1.72
0.57
1.7
2.0
—
—
—
0
0
6
35
1.72
0.57
1.2
1.1
—
—
—
0
0
40
329
1.22
0.56
1.4
1.2
—
—
—
0
0
25
194
1.29
0.56
1.5
1.4
—
—
—
0
0
6
37
1.62
0.55
1.0
1.4
89.43
64.59
mu/l
—
6
27
6
37
1.62
0.55
1.0
1.0
—
—
—
0
0
44
367
1.20
0.54
4.5
4.2
—
—
—
0
0
6
38
1.58
0.54
1.0
1.2
—
—
—
0
0
15
108
1.39
0.53
1.2
1.7
105.10
105.73
ng/l
0.01
15
108
13
91
1.43
0.53
2.2
2.2
185.80
186.95
ug/min
—
5
22
320
3024
1.07
0.52
5.1
5.0
—
—
—
0
0
14
100
1.40
0.52
1.4
1.4
1.99
0.98
promille
1.49
14
80
16
118
1.36
0.50
1.9
1.3
—
—
—
0
0
44
371
1.19
0.50
4.1
3.2
88.03
89.20
%
0.57
44
359
36
298
1.21
0.49
1.3
1.2
—
—
—
0
0
22
172
1.28
0.48
1.3
1.3
—
—
—
0
0
16
119
1.35
0.48
1.7
1.2
—
—
—
0
0
39
328
1.19
0.46
1.3
1.3
280.50
56.71
e6/l
0.37
28
242
7
49
1.43
0.46
1.0
1.2
—
—
—
0
0
11
77
1.43
0.45
1.0
1.0
—
—
—
0
0
5
32
1.56
0.42
1.0
1.1
—
—
—
0
0
5
32
1.56
0.42
11.0
6.3
11.04
5.42
kpa
—
5
32
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
5
34
1.47
0.40
1.4
1.4
28.20
28.56
s
—
5
34
32
269
1.19
0.39
2.0
2.3
1.00
0.89
%
0.45
23
198
29
242
1.20
0.39
3.0
2.7
—
—
—
0
0
5
36
1.39
0.38
2.2
1.8
—
—
—
0
0
13
98
1.33
0.37
1.1
1.4
84.31
84.61
umol/l
0.03
13
98
36
309
1.17
0.36
1.4
1.4
30.90
32.12
iu/l
0.05
22
260
9
71
1.27
0.36
1.0
1.3
32.11
29.72
umol/l
—
9
64
67
743
0.90
0.35
1.2
1.4
—
—
—
0
0
9
126
0.71
0.35
2.4
2.8
—
—
—
0
0
7
54
1.30
0.30
2.0
1.7
38.86
31.06
%
—
7
54
38
334
1.14
0.30
1.4
1.3
265.42
580.32
e6/l
0.41
31
258
13
163
0.80
0.29
1.2
1.1
—
—
—
0
0
7
56
1.25
0.29
1.3
1.4
2.12
1.88
umol/l
—
7
47
13
162
0.80
0.28
1.2
1.1
—
—
—
0
0
88
817
1.08
0.27
1.3
1.3
130.01
204.10
u/ml
1.33
81
755
124
1171
1.06
0.25
4.3
4.1
—
—
—
0
0
17
143
1.19
0.23
1.2
1.0
5.19
2.35
eliau/ml
—
7
49
5
40
1.25
0.22
2.8
1.5
16.00
14.21
pmol/l
—
5
31
38
343
1.11
0.22
1.3
1.3
—
—
—
0
0
14
116
1.21
0.22
2.1
1.8
1.75
1.78
u/field
—
8
63
5
41
1.22
0.22
1.2
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
370.09
—
0
11
0
10
0.00
0.21
0.0
1.3
—
44.60
—
0
5
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
1.41
—
0
5
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
428
4377
0.97
0.20
4.5
4.2
0.00
0.00
estimate
0.96
158
1491
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
39
357
1.09
0.18
1.1
1.1
—
—
—
0
0
15
130
1.16
0.15
1.0
1.0
0.92
4.05
u/ml
—
8
56
331
3379
0.97
0.15
4.6
4.4
1.02
1.02
kg/l
0.50
254
2275
30
275
1.09
0.14
1.1
1.4
—
10.60
—
0
5
18
160
1.13
0.14
1.4
1.2
1.25
1.35
nmol/l
0.18
18
139
78
745
1.05
0.13
1.4
1.3
—
—
—
0
0
28
258
1.09
0.12
1.6
1.8
—
—
—
0
0
12
104
1.16
0.12
1.8
2.7
17.16
16.04
%
0.61
12
104
18
163
1.11
0.10
1.3
1.2
—
—
—
0
0
5
46
1.09
0.09
1.0
1.8
—
—
—
0
0
6
54
1.11
0.09
6.2
3.0
—
—
—
0
0
5
63
0.79
0.08
1.0
1.1
—
—
—
0
0
13
117
1.11
0.08
1.0
1.1
1.58
1.55
u/ml
—
6
56
14
127
1.10
0.08
1.0
1.0
0.47
2.06
u/ml
—
6
47
8
77
1.04
0.07
1.3
1.7
40.44
39.74
g/l
—
8
77
7
80
0.87
0.07
1.1
1.5
4.81
8.10
ug/l
—
7
70
8
91
0.88
0.06
1.3
1.3
0.62
1.23
nmol/l
—
8
62
8
90
0.89
0.06
2.9
2.6
—
—
—
0
0
8
93
0.86
0.06
1.8
1.7
—
—
—
0
0
9
105
0.86
0.06
2.9
2.3
13.17
13.27
%
—
9
105
17
158
1.08
0.06
1.1
1.1
0.07
1.81
u/ml
—
8
81
16
172
0.93
0.06
6.4
4.8
—
—
—
0
0
13
120
1.08
0.05
1.5
1.3
—
—
—
0
0
34
328
1.04
0.04
5.3
5.1
3.10
2.73
mmol/l
0.32
27
232
37
358
1.03
0.04
3.4
2.7
15.79
16.24
%
0.38
37
351
29
279
1.04
0.04
1.8
1.9
2.05
1.68
mmol/l
0.53
29
271
32
309
1.04
0.03
1.4
1.6
—
—
—
0
0
39
379
1.03
0.03
2.4
2.3
232.38
109.92
ug/min
0.44
26
229
24
232
1.04
0.02
1.5
1.2
324.29
291.44
u/ml
0.21
17
120
32
312
1.03
0.02
4.4
3.8
30.76
27.37
mg/l
0.15
23
221
566
5668
1.00
0.00
4.7
4.2
0.02
0.03
estimate
0.34
124
1337
15
154
0.97
0.00
1.0
1.2
—
—
—
0
0
15
154
0.97
0.00
1.0
1.1
—
—
—
0
0
21
206
1.02
0.00
1.3
1.3
—
—
—
0
0
12
122
0.98
0.00
1.2
1.2
—
—
—
0
0
12
119
1.01
0.00
2.6
2.0
1098.42
1089.41
e6/l
0.01
12
109
10
103
0.97
0.00
1.0
1.1
3.63
2.68
u/ml
—
5
42
11
107
1.03
0.00
1.1
1.1
2.87
2.09
mmol/l
0.28
11
98
11
115
0.96
0.00
2.2
2.5
10.71
8.52
mmol/l
0.56
11
115
10
95
1.05
0.00
2.0
2.0
70.10
72.04
%
—
10
89
7
78
0.90
0.00
2.7
2.5
369.86
230.92
e6/l
—
7
72
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
4.74
—
0
5
8
79
1.01
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
—
—
0
0
8
82
0.98
-0.00
1.3
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
6
63
0.95
-0.00
1.0
1.1
1050.33
1523.89
miu/ml
—
6
63
0
5
0.00
-0.00
0.0
1.0
—
0.08
—
0
5
8
79
1.01
-0.00
1.0
1.3
181.64
260.68
pmol/l
—
8
79
6
61
0.98
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
0.17
—
0
5
0
6
0.00
-0.00
0.0
1.5
—
2.43
—
0
6
11
110
1.00
-0.00
1.0
1.7
—
—
—
0
0
5
59
0.85
-0.00
1.0
1.4
183.80
176.45
mmol/24h
—
5
59
6
61
0.98
-0.00
6.2
2.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
194.20
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
27.72
—
0
6
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_RECTOSIGMOID_JUNC and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_RECTOSIGMOID_JUNC 1.169 [1.03, 1.32] 0.013
Birth year 0.997 [0.99, 1.01] 0.425

During the follow-up period (1.1.1998 — 31.12.2019), 680 out of 3167 females with CD2_BENIGN_RECTOSIGMOID_JUNC died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_RECTOSIGMOID_JUNC 1.224 [1.08, 1.39] 0.001
Birth year 0.986 [0.97, 1.0] 0.02

During the follow-up period (1.1.1998 — 31.12.2019), 919 out of 3357 males with CD2_BENIGN_RECTOSIGMOID_JUNC died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_RECTOSIGMOID_JUNC.

N-year risk Females Males
1 0.101% 0.256%
5 0.705% 1.504%
10 1.808% 3.471%
15 3.541% 6.366%
20 6.085% 10.725%

Relationships between endpoints

Index endpoint: CD2_BENIGN_RECTOSIGMOID_JUNC – Benign neoplasm: Rectosigmoid junction

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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