Eccrine sweat disorders

L12_ECCRINESWEAT

sweat gland disease: disorders or sweat glands

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L74 Cause of death: ICD-10 — L74 2 out of 7 registries used, show all original rules.	86
4. Check minimum number of events None	86
5. Include endpoints L12_MILIARUBRA L12_MILIACRYSTAL L12_MILIAPROFUND L12_MILIANAS L12_ANHIDROSIS L12_ECCRINENAS	101
6. Filter based on genotype QC (FinnGen only)	92

Control definitions (FinnGen only)

Control exclude: L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: L60-L75
Name in latin: Morbositates glandularum sudoriferarum eccrinarum

NAME	L12_ECCRINESWEAT
CONTROL_EXCLUDE	L12_DISORDSKINAPPENDIX
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	L12_MILIARUBRA\|L12_MILIACRYSTAL\|L12_MILIAPROFUND\|L12_MILIANAS\|L12_ANHIDROSIS\|L12_ECCRINENAS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L74
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L74
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Eccrine sweat disorders based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	675	388	284
Only index persons	590	348	242
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	39.54	44.02	33.11
Only index persons	40.08	44.15	34.22

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	92	57	35
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	48.11	50.87	43.63

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
95: Matched controls
950

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

L74.0

ICD-10 Finland

Miliaria rubra

266.0

21.5

L74.9

ICD-10 Finland

Eccrine sweat disorder, unspecified

+∞

18.3

L74.8

ICD-10 Finland

Other eccrine sweat disorders

+∞

16.1

TQX10

NOMESCO Finland

Biopsy of skin and subcutaneous tissue

6.4

10.6

L74.4

ICD-10 Finland

Anhidrosis

+∞

8.5

L74.1

ICD-10 Finland

Miliaria crystallina

+∞

8.5

L74.3

ICD-10 Finland

Miliaria, unspecified

86.6

7.5

ZZR00

NOMESCO Finland

Flap of skin

32.8

7.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3010375) cycloSPORINE [Mass/volume] in Blood

+∞

5.25

28.8

0.0

83.00

—

ug/l

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

260

2.10

3.07

2.6

2.4

54.29

72.91

u/l

0.57

243

(40768443) Skin Pathology biopsy report

3.42

2.75

1.5

1.2

—

(3018010) Neutrophils/Leukocytes in Blood

409

1.98

2.66

5.3

6.8

57.61

57.69

0.02

389

(3019198) Lymphocytes [#/volume] in Blood

446

1.94

2.44

6.2

6.6

1.89

1.86

e9/l

0.08

400

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

637

2.25

2.42

4.0

4.6

14.98

14.77

pmol/l

0.24

574

(42870588) Differential panel, method unspecified - Blood

297

1.90

2.39

5.4

5.9

—

(3006315) Basophils [#/volume] in Blood

440

1.90

2.33

6.3

6.6

0.04

e9/l

0.49

382

(3013115) Eosinophils [#/volume] in Blood

455

1.86

2.20

6.4

6.9

0.23

0.18

e9/l

1.07

403

(3015235) Bicarbonate [Moles/volume] in Capillary blood

3.40

2.15

3.0

2.1

26.84

25.70

mmol/l

—

(3001604) Monocytes [#/volume] in Blood

438

1.83

2.13

6.4

6.6

0.60

0.56

e9/l

0.57

382

(3022313) Gas panel - Capillary blood

2.82

2.07

3.4

2.0

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.18

2.07

1.7

1.8

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

3.26

2.06

1.3

1.5

—

(3028626) Oxygen [Partial pressure] in Capillary blood

3.26

2.06

4.3

2.0

7.91

8.73

kpa

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

162

1.93

2.04

4.4

2.9

9.75

316.83

ng/l

1.05

121

(3026008) Bacteria identified in Urine by Culture

248

1.81

1.98

3.1

2.9

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

136

1.91

1.80

2.1

1.8

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

502

1.76

1.79

4.0

5.2

6.74

6.62

mmol/l

0.18

468

(3048689) Calprotectin [Mass/mass] in Stool

114

1.96

1.73

3.1

2.7

524.04

104.27

ug/g

0.94

(3013650) Neutrophils [#/volume] in Blood by Automated count

488

1.70

1.65

10.3

10.8

4.39

4.17

e9/l

0.24

431

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

251

1.70

1.63

2.3

3.3

1094.68

1094.60

ng/l

0.00

215

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

2.82

1.61

1.3

1.6

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

122

1.81

1.41

3.4

2.4

2.47

2.33

g/l

0.35

107

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.87

1.38

1.9

1.6

—

(4094501) Cardiovascular stress test using bicycle ergometer

2.60

1.32

1.0

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

2.40

1.30

1.5

1.3

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

822

2.31

1.28

19.6

15.0

23.44

23.76

mg/l

0.03

655

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

302

1.56

1.27

5.4

3.1

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.86

1.24

1.9

2.2

—

(3003191) Choriogonadotropin [Presence] in Serum or Plasma

2.72

1.23

2.6

1.6

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

2.39

1.20

1.3

1.6

—

(3018418) pH of Serum or Plasma

260

1.55

1.18

5.2

3.7

7.39

7.40

1.17

181

(3022948) Iron [Moles/volume] in Serum or Plasma

130

1.68

1.14

3.4

2.3

11.21

13.60

umol/l

0.71

118

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

2.04

1.12

2.3

2.7

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

416

1.49

1.09

8.3

7.0

1.22

1.21

mmol/l

0.86

357

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

2.34

1.04

1.2

1.6

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.96

1.04

2.2

2.6

—

(3019060) Gas panel - Arterial blood

1.96

1.04

1.7

4.1

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

381

1.46

1.01

2.6

2.5

—

estimate

—

(3003396) Base excess in Arterial blood by calculation

102

1.68

0.98

1.9

8.4

-0.43

0.72

mmol/l

0.27

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

335

1.45

0.98

3.2

4.0

21.91

38.50

ng/l

0.67

233

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.74

0.97

1.3

1.7

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

197

1.52

0.97

1.8

2.2

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.69

0.94

4.5

3.5

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

300

1.44

0.92

2.8

3.2

30.24

32.24

u/l

0.22

284

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

2.14

0.91

5.2

3.1

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.67

0.91

1.5

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

130

1.58

0.90

1.7

1.5

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

115

1.58

0.84

3.9

2.4

18.22

23.30

1.01

107

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

0.00

0.78

0.0

1.4

—

211.57

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

100

1.59

0.78

3.6

4.5

28.13

32.67

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

224

1.42

0.78

1.5

1.3

9.40

2.50

u/ml

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.81

0.77

1.5

1.3

—

(3000494) Fungus identified in Specimen by Culture

109

1.56

0.77

1.5

1.4

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

347

1.38

0.76

1.7

2.0

89.09

98.12

pmol/l

0.71

167

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

1.70

0.76

1.1

1.3

—

28.10

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

2.14

0.75

1.4

1.5

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.91

0.75

2.3

2.2

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

171

1.46

0.75

1.3

11.35

33.54

iu/ml

1.38

(3017181) Myelocytes/Leukocytes in Blood

1.59

0.74

2.9

4.2

0.75

0.95

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.61

0.72

2.9

1.3

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

1.76

0.71

2.1

3.8

46.17

46.73

—

(3032080) INR in Blood by Coagulation assay

399

1.35

0.71

12.3

11.8

1.18

1.19

inr

0.01

322

(3023368) Bacteria identified in Blood by Culture

228

1.39

0.70

4.1

4.2

—

(3019977) pH of Arterial blood

103

1.54

0.70

2.0

8.3

7.42

7.43

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

1.90

0.69

1.2

1.6

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.90

0.69

1.2

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

531

1.35

0.68

3.6

3.1

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

193

1.40

0.67

3.2

2.5

2.35

3.02

mg/l

1.25

166

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

102

0.56

0.66

2.0

1.5

—

(4024509) Urine culture

1.76

0.64

2.0

1.5

—

(4034850) Laboratory test

1.76

0.64

15.0

6.0

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.76

0.64

2.6

2.0

—

(3049717) Cytology report of Urine Cyto stain

1.76

0.64

2.4

2.7

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

839

1.66

0.63

6.3

5.7

2.73

2.72

mmol/l

0.01

778

(3023351) European house dust mite IgE Ab [Units/volume] in Serum

0.00

0.61

0.0

1.2

—

2.09

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

1.55

0.60

1.2

2.9

0.22

0.23

g/l

0.06

(46235355) HIV 1 and 2 tests - Meaningful Use set

162

1.38

0.56

2.2

2.0

—

(3024354) Oxygen [Partial pressure] in Venous blood

1.58

0.55

1.9

2.9

3.73

4.10

kpa

—

(3018095) Leukocytes [#/volume] in Urine

324

1.29

0.52

5.5

3.9

1386.47

55.38

e6/l

0.47

218

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

174

1.34

0.51

1.8

1.6

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

102

1.44

0.51

2.4

—

(3002256) Pathology report gross observation

103

1.42

0.48

1.4

1.2

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.49

0.48

1.6

1.5

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.46

0.47

1.0

—

(40768804) Tissue Pathology biopsy report

328

1.26

0.47

3.1

2.0

—

(3044640) Blood type and Crossmatch panel - Blood

262

1.27

0.45

2.1

2.3

—

(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma

1.47

0.44

5.1

2.8

14.26

22.46

u/ml

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.44

0.43

1.3

1.7

—

(40761535) Cells panel - Urine sediment

1.41

0.43

6.3

3.8

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

0.41

0.0

1.5

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.41

0.0

1.2

—

(4195642) Thrombophilia screening test

0.00

0.41

0.0

1.2

—

(3009508) Creatinine [Moles/volume] in Urine

284

1.25

0.41

4.6

3.2

6.64

8.05

mmol/l

0.63

240

(3010726) Horse dander IgE Ab [Units/volume] in Serum

0.00

0.41

0.0

1.1

—

1.64

—

(3008401) Mugwort IgE Ab [Units/volume] in Serum

0.00

0.40

0.0

1.1

—

0.75

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.40

0.0

1.1

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.40

0.0

1.1

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

1.45

0.40

1.2

1.6

989.56

861.90

mu/l

—

(3029937) Albumin [Presence] in Urine by Test strip

266

1.25

0.39

7.5

4.0

0.00

estimate

—

(3003888) Timothy IgE Ab [Units/volume] in Serum

0.00

0.39

0.0

1.1

—

4.66

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

827

1.42

0.38

5.8

4.9

1.37

1.48

mmol/l

2.08

763

(3030467) Casts [#/volume] in Urine by Automated count

239

1.24

0.37

4.4

2.9

0.09

0.31

e6/l

1.42

161

(3021601) Nitrite [Presence] in Urine by Test strip

474

1.21

0.37

5.6

4.0

0.00

estimate

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

795

1.35

0.37

5.0

4.2

1.38

1.32

mmol/l

0.34

729

(40760892) CBC W Ordered Manual Differential panel - Blood

212

1.24

0.35

6.8

5.2

—

(3035350) Ketones [Presence] in Urine by Test strip

476

1.20

0.35

5.6

4.0

0.00

estimate

—

(3020682) Albumin/Creatinine [Ratio] in Urine

270

1.22

0.34

5.3

3.8

10.38

8.23

mg/mmol

0.11

157

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

1.37

0.34

4.9

4.5

2.77

57.82

ug/l

0.56

(3021447) Carbon dioxide [Partial pressure] in Venous blood

1.35

0.31

2.6

3.2

6.63

5.81

kpa

0.61

(3002582) Erythrocytes [#/volume] in Urine

282

1.20

0.31

5.2

3.0

13.08

266.97

e6/l

0.54

206

(3002385) Erythrocyte [DistWidth] in Red Blood Cells

684

1.22

0.30

17.6

19.6

13.85

13.55

0.71

678

(3012516) Albumin [Mass/volume] in Urine

264

1.20

0.30

4.3

3.3

46.67

56.92

mg/l

0.11

162

(3021440) Promyelocytes/Leukocytes in Blood

1.33

0.29

2.6

4.5

0.00

0.08

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

117

0.75

0.29

1.3

1.9

1.57

1.52

—

104

(3017143) Hepatitis C virus Ab [Presence] in Serum

104

1.29

0.28

1.3

1.7

—

(3002179) Metamyelocytes/Leukocytes in Blood

1.32

0.27

2.6

4.2

0.00

0.88

—

(3012544) pH of Venous blood

1.32

0.27

2.7

3.1

7.36

7.39

—

(4035726) Immunohistochemistry procedure

0.67

0.27

2.0

1.4

—

(3009261) Glucose [Presence] in Urine by Test strip

484

1.16

0.26

5.7

4.0

0.00

estimate

—

(3000991) Gas panel - Venous blood

0.73

0.25

4.8

8.4

—

(3019150) Specific gravity of Urine by Refractometry

210

1.19

0.25

7.4

3.9

1.01

1.02

kg/l

0.68

135

(3025159) Blasts/Leukocytes in Blood

1.28

0.24

2.7

4.6

0.00

0.36

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.30

0.23

2.0

1.3

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

1.26

0.23

3.4

3.5

30.26

24.84

mmol/l

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

126

1.23

0.22

2.5

7.8

102.20

104.02

mmol/l

0.86

126

(3023420) DNA double strand Ab [Units/volume] in Serum

1.23

0.22

1.6

2.0

—

3.34

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

136

1.21

0.22

1.9

1.6

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

369

1.15

0.22

5.9

3.8

0.00

estimate

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(40768800) Prostate Pathology biopsy report

0.00

0.21

0.0

1.3

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.21

0.0

1.6

—

19.09

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.2

—

(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum

0.00

0.21

0.0

1.3

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.1

—

197.78

—

(3020874) Milk IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

0.13

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(3005136) Cladosporium herbarum IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

1.45

—

(3042631) Mycobacterium sp identified in Specimen

0.00

0.21

0.0

3.7

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.21

0.0

1.3

—

(40768795) Lymph node Pathology biopsy report

0.00

0.21

0.0

1.0

—

(3011648) Oxygen content in Venous blood

0.00

0.21

0.0

1.9

—

11.04

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

775

1.20

0.21

7.0

6.2

39.02

38.98

mmol/mol

0.02

731

(40759850) Jo-1 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.2

—

(3017732) Neutrophils [#/volume] in Blood

118

1.22

0.20

4.9

2.8

3.55

6.55

e9/l

—

106

(3020961) Endomysium IgA Ab [Titer] in Serum

1.24

0.20

1.2

1.1

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

0.20

0.0

1.5

—

(3000012) Reticulocyte production index

0.00

0.20

0.0

1.8

—

0.87

—

(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay

0.00

0.20

0.0

1.7

—

0.44

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.26

0.19

1.6

1.9

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

1.16

0.19

2.0

2.4

24.72

24.77

mmol/l

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

158

1.17

0.18

2.1

2.9

2.44

mmol/l

0.03

143

(3023520) Reticulocytes [#/volume] in Blood

1.21

0.17

4.1

2.9

86.88

71.89

e9/l

—

(40761536) Microorganisms panel - Urine sediment

1.17

0.17

4.8

3.5

—

(3042936) Bacteria identified in Isolate by Culture

130

1.18

0.17

2.1

2.0

—

(40768797) Stomach Pathology biopsy report

121

1.18

0.16

1.4

1.3

—

(3003694) ABO and Rh group [Type] in Blood

243

0.88

0.16

1.6

1.4

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

0.83

0.14

5.3

2.1

333.38

371.03

nmol/l

—

(3014051) Protein [Presence] in Urine by Test strip

261

0.89

0.13

2.3

3.2

—

0.25

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

802

1.16

0.13

5.8

5.0

5.91

5.85

mmol/l

0.18

729

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.18

0.12

6.5

6.7

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

144

1.13

0.11

2.9

2.7

0.19

1.09

e6/l

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.12

0.10

1.6

—

(3015736) pH of Urine

372

1.08

0.10

5.3

3.6

6.17

6.24

0.09

199

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

1.09

0.10

2.6

0.68

0.67

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.04

0.09

2.6

1.22

1.32

—

(1761868) Lipid panel - Serum or Plasma

363

1.08

0.09

3.5

3.2

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.08

0.09

1.0

2.8

—

(3020630) Protein [Mass/volume] in Serum or Plasma

1.05

0.08

1.6

3.3

69.20

67.78

g/l

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

0.82

0.08

3.3

3.0

28.67

28.84

u/l

—

(3000492) Spirometry study

0.84

0.07

2.3

1.5

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

172

0.92

0.06

3.7

4.2

19.87

21.12

—

(40758558) Short blood count panel - Blood

273

0.93

0.06

7.2

6.7

—

(3041096) Erythrocytes [Presence] in Urine by Automated

277

1.07

0.06

3.6

3.3

0.00

estimate

—

(3022145) Colonoscopy Study observation

110

1.10

0.05

1.4

1.3

—

(3021960) Folate [Moles/volume] in Serum or Plasma

230

1.06

0.04

1.7

17.35

19.68

nmol/l

0.36

187

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

380

1.04

0.03

2.2

1.9

1.42

1.44

mmol/l

0.05

317

(3002173) Hemoglobin [Mass/volume] in Arterial blood

1.08

0.02

2.3

8.9

129.90

123.15

g/l

—

(3007164) IgA [Mass/volume] in Serum or Plasma

204

1.04

0.00

1.4

2.74

2.73

g/l

0.00

117

(40761511) CBC panel - Blood by Automated count

848

1.02

0.00

17.3

13.6

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

158

1.02

0.00

1.5

1.3

1.42

13.75

u/ml

—

(3021589) Normoblasts [#/volume] in Blood

395

1.02

0.00

11.8

13.0

0.01

0.00

e9/l

0.46

321

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

131

0.99

0.00

3.0

2.9

2.00

2.54

e6/l

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.4

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

0.0

11.6

—

0.62

—

(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture

0.00

0.0

1.8

—

(3002619) Bacteria identified in Specimen by Culture

0.00

0.0

1.0

—

(21494434) Karyotype in Bone marrow

0.00

0.0

1.0

—

(3004451) EKG impression Narrative

0.00

0.0

1.4

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

0.0

1.1

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

3.2

—

4.69

—

(3018333) Ribosomal P Ab [Presence] in Serum

0.00

0.0

1.4

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

3.2

—

9.96

—

(3013727) Leukocytes other/Leukocytes in Blood

0.00

0.0

1.6

—

57.80

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

0.0

1.1

—

(3006270) Folate [Moles/volume] in Blood

0.00

0.0

1.0

—

336.40

—

(3034426) Prothrombin time (PT)

0.00

0.0

1.2

—

29.20

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

0.0

4.0

—

2.01

—

(3045788) Cell count panel - Pleural fluid

0.00

0.0

1.7

—

(40768441) Liver Pathology biopsy report

0.00

0.0

1.6

—

(40757494) Bilirubin.total [Moles/volume] in Blood

0.00

0.0

1.6

—

(37208534) Antinuclear antibody arbitrary concentration in serum

0.00

0.0

1.0

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

0.0

1.3

—

(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid

0.00

0.0

1.1

—

8.86

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

1.3

—

5.03

—

(3038026) Centromere Ab [Units/volume] in Serum

0.00

0.0

1.3

—

(40768806) Pleura Pathology biopsy report

0.00

0.0

2.9

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.0

1.0

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

0.0

1.0

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

291.00

—

(3006442) Creatine [Moles/volume] in Serum or Plasma

0.00

0.0

2.1

—

62.57

—

(3045142) Bone marrow Pathology biopsy report

0.00

0.0

1.4

—

(3051651) Icteric interference index of Serum or Plasma

0.00

0.0

1.8

—

0.80

—

(3006653) Thiamine [Moles/volume] in Blood

0.00

0.0

1.0

—

147.60

—

(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma

0.00

0.0

2.2

—

56.60

—

(40760543) Extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.0

—

(3003129) Base excess in Capillary blood by calculation

0.00

0.0

1.3

—

2.96

—

(3037534) Parathyrin related protein [Mass/volume] in Serum or Plasma

0.00

0.0

2.0

—

102.94

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

-0.00

0.0

1.1

—

(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose

0.00

-0.00

0.0

1.7

—

7.67

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

-0.00

0.0

1.8

—

564.17

—

(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

25.3

—

1397.78

—

(40765096) Chromosome analysis panel by Banding

0.00

-0.00

0.0

1.2

—

(4211845) Urine protein measurement

0.00

-0.00

0.0

1.8

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(3005570) Glucose [Moles/volume] in Urine

0.00

-0.00

0.0

2.7

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

15.3

—

747.22

—

(3052649) Adenosine deaminase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

13.17

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

-0.00

0.0

1.2

—

(3029023) Hepatitis E virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

0.95

-0.00

1.9

1.3

—

(3002222) Hepatitis E virus IgM Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3028433) Virus identified in Specimen by Culture

0.00

-0.00

0.0

1.7

—

(42529582) MDA5 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.5

—

1.77

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

-0.00

0.0

1.0

—

(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

-0.00

0.0

4.7

—

79.83

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

-0.00

0.0

1.3

—

(3013637) Mi-2 Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3007368) IgG [Mass/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

38.98

—

(3006922) Hepatitis E virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

-0.00

0.0

1.3

—

5.93

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.4

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.00

-0.00

0.0

1.3

—

(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

-0.00

0.0

1.3

—

(21494755) Public health laboratory ask at order entry panel

0.89

-0.00

1.4

—

(3025941) Bacteria identified in Stool by Culture

0.89

-0.00

1.8

1.2

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.4

—

(36660697) Celiac disease serology panel - Serum

0.96

-0.00

1.4

1.2

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

0.90

-0.00

1.8

1.1

—

Mortality – FinRegistry

↥

Association

Association between endpoint L12_ECCRINESWEAT and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_ECCRINESWEAT.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: L12_ECCRINESWEAT – Eccrine sweat disorders

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Eccrine sweat disorders

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints