pinguecula: A yellowish thickened lesion on the conjunctiva near the cornea representing a benign degenerative change in the conjunctiva caused by the leakage and deposition of certain blood proteins through the permeable capillaries near the limbus.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
891 |
4. Check minimum number of eventsNone |
891 |
5. Include endpointsNone |
891 |
6. Filter based on genotype QC (FinnGen only) |
792 |
Control definitions (FinnGen only)
- Control exclude
- H7_CONJUNCTIVA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H11
- Name in latin
- Degenerationes et deposita conjunctivae
Similar endpoints
↥List of similar endpoints to
conjunctival degenerations and deposits
based on the number of shared cases.
Similar with more cases:
- Other disorders of conjunctiva
- Disorders of conjunctiva
- Diseases of the eye and adnexa
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5600 | 3529 | 2024 |
| Only index persons | 5007 | 3200 | 1807 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.10 | 0.06 |
| Only index persons | 0.10 | 0.12 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 53.72 | 53.94 | 53.55 |
| Only index persons | 52.74 | 52.84 | 52.55 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 792 | 506 | 286 |
| Unadjusted period prevalence (%) | 0.16 | 0.18 | 0.13 |
| Median age at first event (years) | 53.55 | 51.94 | 56.41 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 827
- Matched controls
- 8270
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
+∞
307.7
808
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
4.8
99.3
577
2692
H04.10
ICD-10 Finland
Dry eye syndrome
5.6
94.9
218
494
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
163.8
84.9
88
6
S01GX01
ATC
cromoglicic acid; ophthalmic
4.5
73.1
226
643
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
11.5
61.7
66
62
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.5
35.3
364
1981
S01KA02
ATC
hypromellose; ophthalmic
9.0
34.3
43
50
S01BA01
ATC
dexamethasone; ophthalmic
5.6
31.5
62
118
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
4.3
28.8
79
199
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
30.6
28.7
38
13
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.6
28.4
208
949
S01GX02
ATC
levocabastine; ophthalmic
5.0
27.3
61
130
H57.1
ICD-10 Finland
Ocular pain
4.8
24.6
57
125
H11.0
ICD-10 Finland
Pterygium
57.9
24.2
28
5
S01BC03
ATC
diclofenac; ophthalmic
6.3
23.9
41
68
H10.4
ICD-10 Finland
Chronic conjunctivitis
78.9
20.8
23
*
CF2S4
NOMESCO Finland
Photography of conjunctiva
78.9
20.8
23
*
L01BA01
ATC
methotrexate; systemic
4.3
20.4
54
132
H02AB06
ATC
prednisolone; systemic
2.0
20.4
437
2987
F01
ICPC
Eye pain
5.1
20.3
44
91
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
3.7
20.3
68
197
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.7
20.2
122
500
CD2S4
NOMESCO Finland
Photography of eye
27.8
20.1
27
10
3725A
ICD-9 Finland
Disorders of conjunctiva, Conjunctival degenerations and deposits
+∞
19.9
19
*
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
8.4
19.7
26
32
S01GX08
ATC
ketotifen; ophthalmic
5.1
19.2
41
84
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
5.3
18.5
38
75
P01BA02
ATC
hydroxychloroquine; oral
2.8
18.3
100
388
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.9
18.3
55
148
H15.1
ICD-10 Finland
Episcleritis
6.9
17.9
28
42
S01GX05
ATC
lodoxamide; ophthalmic
23.4
17.8
25
11
CFA20
NOMESCO Finland
Biopsy of conjunctiva
68.1
17.8
20
*
H16.9
ICD-10 Finland
Keratitis, unspecified
6.5
17.7
29
46
A02BC03
ATC
lansoprazole; oral
1.9
17.2
283
1743
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
17.1
283
1746
S01BA07
ATC
fluorometholone; ophthalmic
7.3
17.0
25
35
H16.0
ICD-10 Finland
Corneal ulcer
3.4
16.6
61
188
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.4
15.6
120
549
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
15.6
214
1231
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
15.6
319
2095
E0000UV, ,
ATC
1.8
15.4
358
2440
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
14.9
278
1767
S01AD03
ATC
aciclovir; ophthalmic
3.7
14.1
45
126
N03AX16
ATC
[U] pregabalin
1.9
14.0
218
1303
A02BC05
ATC
esomeprazole; systemic
1.8
14.0
361
2519
S01AX11
ATC
[U] ofloxacin
3.8
13.7
43
119
3401
FHL
Removal of local modification or taking a specimen in the operating room
+∞
13.6
13
*
H00.1
ICD-10 Finland
Chalazion
3.5
13.5
48
145
G44.2
ICD-10 Finland
Tension-type headache
2.1
13.3
136
699
K59.09
ICD-10 Finland
Constipation, unspecified
2.6
13.2
78
315
M54.4
ICD-10 Finland
Lumbago with sciatica
2.0
13.0
171
963
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.7
13.0
72
281
H01.0
ICD-10 Finland
Blepharitis
2.9
13.0
63
229
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.0
12.9
167
935
A02BC01
ATC
omeprazole; systemic
1.8
12.7
248
1584
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
4.7
12.7
29
63
S01AA01
ATC
chloramphenicol; ophthalmic
3.1
12.7
53
177
D86.0
ICD-10 Finland
Sarcoidosis of lung
5.7
12.5
23
41
N02AX02
ATC
tramadol; systemic, rectal
1.7
12.2
382
2782
S01XA18
ATC
ciclosporin; ophthalmic
16.2
12.2
19
12
S01GX04
ATC
nedocromil; ophthalmic
10.3
12.0
23
23
M01AX17
ATC
nimesulide; oral
1.8
12.0
225
1418
R42
ICD-10 Finland
Dizziness and giddiness
1.8
11.6
216
1356
R01AD01
ATC
beclometasone; nasal
2.0
11.6
138
749
H10.5
ICD-10 Finland
Blepharoconjunctivitis
5.8
11.5
21
37
M54.6
ICD-10 Finland
Pain in thoracic spine
2.4
11.3
80
351
H11.8
ICD-10 Finland
Other specified disorders of conjunctiva
35.6
11.3
14
*
WZC00
NOMESCO Finland
Treatment plan or consultation
1.7
11.3
314
2204
UJF32
NOMESCO Finland
Coloscopy
1.7
11.1
241
1579
WZC30
NOMESCO Finland
Teaching
1.9
11.1
154
880
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
11.1
196
1210
J05AB01
ATC
aciclovir; systemic
1.8
11.1
195
1202
M79.0
ICD-10 Finland
Rheumatism, unspecified
3.2
11.0
43
138
H11.4
ICD-10 Finland
Other conjunctival vascular disorders and cysts
43.9
10.9
13
*
SAA01
NOMESCO Finland
Simple examination of mouth
1.7
10.9
579
4778
S01GX09
ATC
olopatadine; ophthalmic
4.8
10.8
24
51
R06.0
ICD-10 Finland
Dyspnoea
1.7
10.7
244
1617
R06AE07
ATC
cetirizine; oral
1.6
10.7
341
2470
H11.3
ICD-10 Finland
Conjunctival haemorrhage
3.4
10.7
39
120
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.0
10.5
136
758
CCC00
NOMESCO Finland
Occlusion of lacrimal punctum or canaliculus
+∞
10.4
10
*
J02AC01
ATC
fluconazole; systemic
1.6
10.3
319
2288
XCK10
NOMESCO Finland
Photography of fundus of eye
2.2
10.3
90
433
N06AA09
ATC
amitriptyline; systemic
2.1
10.3
99
495
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.7
10.2
230
1517
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.4
10.1
72
317
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.3
10.1
82
383
H02AB04
ATC
methylprednisolone; systemic
2.0
10.1
127
701
H19.3
ICD-10 Finland
Keratitis and keratoconjunctivitis in other diseases classified elsewhere
40.6
10.0
12
*
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
9.9
242
1629
K07.60
ICD-10 Finland
Snapping jaw
2.7
9.7
52
200
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.2
9.5
82
393
F70
ICPC
Conjunctivitis infectious
3.7
9.5
30
84
A01AB09
ATC
miconazole; local oral
2.2
9.4
84
408
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
9.4
165
1012
XCK00
NOMESCO Finland
Perimetry
2.5
9.4
61
258
M25.5
ICD-10 Finland
Pain in joint
1.6
9.4
277
1955
J01FA10
ATC
azithromycin; systemic
1.6
9.1
444
3513
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
5.1
9.1
19
38
S01GX06
ATC
emedastine; ophthalmic
11.6
9.1
16
14
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
37.1
9.0
11
*
S01BA04
ATC
prednisolone; ophthalmic
3.9
9.0
26
68
M03BX02
ATC
tizanidine; oral
1.6
9.0
501
4084
D07AC01
ATC
betamethasone; topical
1.6
8.9
297
2151
R01AD09
ATC
mometasone; nasal
1.6
8.9
353
2664
R51.80
ICD-10 Finland
Headache
1.8
8.8
133
777
A07EC01
ATC
sulfasalazine; oral, rectal
2.2
8.8
75
358
R06AX22
ATC
ebastine; oral
1.8
8.8
134
787
A02BC02
ATC
pantoprazole; systemic
1.6
8.7
572
4823
R03AC02
ATC
salbutamol; inhalant
1.6
8.7
440
3496
M54.5
ICD-10 Finland
Low back pain
1.6
8.7
301
2196
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
8.7
359
2729
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.4
8.6
62
275
CG2S4
NOMESCO Finland
Photography of cornea
11.7
8.6
15
13
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.4
8.6
59
256
G51.0
ICD-10 Finland
Bell palsy
3.6
8.6
28
80
S29
ICPC
Skin symptom/complaint other
1.7
8.4
175
1122
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.0
8.4
93
489
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
5.0
8.4
18
37
CGE50
NOMESCO Finland
Excision of pterygium
+∞
8.3
8
*
R03BA01
ATC
beclometasone; inhalant
1.9
8.3
117
668
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
8.7
8.3
17
20
SAA03
NOMESCO Finland
Extended examination of mouth
1.6
8.3
304
2243
F02
ICPC
Red eye
2.8
8.3
42
157
A02BA02
ATC
ranitidine; systemic
1.7
8.3
169
1079
Z01.2
ICD-10 Finland
Dental examination
1.5
8.2
359
2751
S01ED01
ATC
timolol; ophthalmic
3.1
8.2
34
113
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
8.2
189
1245
L04AA01
ATC
[U] ciclosporin
6.6
8.2
20
31
M01CB01
ATC
sodium aurothiomalate; parenteral
4.8
8.1
18
38
A01AB04
ATC
amphotericin B; local oral
2.5
8.1
49
200
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
8.1
326
2452
Z71.8
ICD-10 Finland
Other specified counselling
1.6
8.1
274
1985
F45.8
ICD-10 Finland
Other somatoform disorders
2.4
8.0
54
232
M79.7
ICD-10 Finland
Fibromyalgia
2.9
8.0
36
126
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.3
7.9
58
259
R01AD58
ATC
fluticasone, combinations; nasal
1.7
7.9
176
1149
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.2
7.9
70
339
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.2
7.8
67
320
J01AA02
ATC
doxycycline; systemic
1.6
7.8
633
5528
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.6
7.8
213
1464
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.8
7.8
121
714
A03FA02
ATC
cisapride; oral, rectal
2.2
7.7
68
328
L04AA13
ATC
[U] leflunomide
3.3
7.7
28
86
M01AX01
ATC
nabumetone; oral
2.6
7.7
44
175
SFA10
NOMESCO Finland
One-surface restoration
1.5
7.7
430
3459
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.2
7.7
63
296
L28
ICPC
Limited function/disability (L)
1.7
7.7
169
1100
M79.1
ICD-10 Finland
Myalgia
1.8
7.6
129
779
RD211, ,
NOMESCO Finland
2.6
7.6
44
176
R03AC03
ATC
terbutaline; inhalant
1.8
7.5
110
636
KMAK, ,
NOMESCO Finland
1.5
7.5
387
3056
C10AC01
ATC
colestyramine; oral
3.2
7.5
29
93
J01FA06
ATC
roxithromycin; oral
1.5
7.5
320
2430
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.6
7.4
213
1478
C05AA08
ATC
fluocortolone; rectal, topical
1.8
7.4
117
692
R83
ICPC
Respiratory infection other
1.6
7.4
176
1167
S06.0
ICD-10 Finland
Concussion
1.9
7.4
95
527
RF420, ,
NOMESCO Finland
4.1
7.4
20
50
R06AX26
ATC
fexofenadine; oral
2.3
7.4
55
248
M05BA07
ATC
risedronic acid; oral
2.9
7.3
34
121
J01CA04
ATC
amoxicillin; systemic
1.6
7.3
645
5686
D07AC13
ATC
mometasone; topical
1.6
7.3
230
1631
R01AD12
ATC
fluticasone furoate; nasal
1.6
7.3
224
1579
H10.8
ICD-10 Finland
Other conjunctivitis
9.5
7.3
14
15
SPAT1216
SPAT
Assessment of functional ability
1.7
7.3
138
862
F03
ICPC
Eye discharge
2.2
7.2
60
283
M01AH01
ATC
celecoxib; oral
1.7
7.2
157
1018
L01
ICPC
Neck symptom/complaint
1.7
7.1
132
818
F29
ICPC
Eye symptom/complaint other
1.9
7.1
90
496
SPAT1263
SPAT
Sampling
1.5
7.1
328
2524
N03AX12
ATC
[U] gabapentin; oral
1.7
7.1
140
884
L02
ICPC
Back symptom/complaint
1.9
7.1
91
505
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
7.0
116
696
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
7.0
155
1008
R13
ICD-10 Finland
Dysphagia
2.1
7.0
66
328
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
7.0
305
2318
A07AA02
ATC
nystatin; oral
2.2
7.0
55
254
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
6.9
223
1586
R05
ICPC
Cough
1.6
6.9
203
1414
A02BA04
ATC
nizatidine; systemic
2.0
6.9
70
357
SPAT1153
SPAT
Removal of sutures
1.5
6.9
264
1951
R07.0
ICD-10 Finland
Pain in throat
2.2
6.9
56
262
N05CF01
ATC
zopiclone; oral
1.5
6.9
270
2005
M48.0
ICD-10 Finland
Spinal stenosis
1.8
6.9
117
708
SPAT1325
SPAT
Vaccination
1.5
6.9
262
1935
H16.2
ICD-10 Finland
Keratoconjunctivitis
8.4
6.8
14
17
D07BC01
ATC
betamethasone and antiseptics; topical
1.9
6.8
96
548
R05
ICD-10 Finland
Cough
1.6
6.8
177
1198
XCH00
NOMESCO Finland
Eye pressure measurement
2.4
6.8
47
205
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
6.8
138
878
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
6.7
142
911
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
3.5
6.7
23
68
L04AX03
ATC
methotrexate; systemic
1.9
6.7
86
477
R07.3
ICD-10 Finland
Other chest pain
1.8
6.7
96
552
H01
ICPC
Ear pain/earache
1.9
6.7
93
530
H02.3
ICD-10 Finland
Blepharochalasis
2.1
6.6
63
314
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.2
6.6
25
79
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.9
6.6
86
479
C08CA13
ATC
lercanidipine; oral
1.7
6.6
127
795
L04AD01
ATC
ciclosporin; systemic
3.9
6.6
19
50
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.8
6.5
97
563
L08
ICPC
Shoulder symptom/complaint
1.6
6.5
191
1330
R1250
NOMESCO Finland
Evaluation of functional capability
3.0
6.5
28
96
R03AC13
ATC
formoterol; inhalant
2.4
6.5
45
197
D07CC01
ATC
betamethasone and antibiotics; topical
1.8
6.5
103
611
Z3229
NOMESCO Finland
Other healthcare associate professional
2.0
6.5
69
359
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.7
6.5
119
736
E000001, ,
ATC
1.6
6.4
145
946
L03
ICPC
Low back symptom/complaint
1.5
6.4
236
1725
M01AH05
ATC
etoricoxib; oral
1.5
6.3
491
4148
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.5
6.3
37
150
H19.2
ICD-10 Finland
Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
+∞
6.3
6
*
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
6.2
418
3429
H06.2
ICD-10 Finland
Dysthyroid exophthalmos
26.9
6.2
8
*
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
6.2
351
2789
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.1
6.2
61
308
N30.0
ICD-10 Finland
Acute cystitis
1.6
6.2
141
922
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.1
6.2
55
267
RF410, ,
NOMESCO Finland
4.0
6.2
17
43
Z00.0
ICD-10 Finland
General medical examination
1.6
6.2
161
1088
R5110, ,
SPAT
1.9
6.1
83
468
J01MA02
ATC
ciprofloxacin; systemic
1.5
6.1
303
2346
ZYC01
NOMESCO Finland
Remote contact by phone
2.1
6.1
56
275
R52.2
ICD-10 Finland
Other chronic pain
2.5
6.1
38
158
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.1
6.1
25
83
WW200, ,
SPAT
1.5
6.1
251
1874
J45.1
ICD-10 Finland
Nonallergic asthma
2.0
6.1
61
310
G43.9
ICD-10 Finland
Migraine, unspecified
2.3
6.1
45
203
L88
ICPC
Rheumatoid/seropositive arthritis
2.4
6.1
39
165
CCD60
NOMESCO Finland
Transnasal dacryocystorhinostomy
10.1
6.0
11
11
J01FF01
ATC
clindamycin; systemic
1.5
6.0
207
1489
S01FA04
ATC
cyclopentolate; ophthalmic
6.1
6.0
15
25
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.5
6.0
199
1420
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
340
2404
1.70
12.08
3.2
2.6
68.57
96.09
u/l
0.37
321
2218
392
2963
1.61
10.21
3.9
3.9
31.30
89.33
ng/l
1.22
283
2218
519
4230
1.61
9.63
10.2
9.9
4.08
4.09
e9/l
0.00
458
3689
306
2213
1.61
9.35
5.5
4.3
0.00
0.01
estimate
0.96
97
782
486
3928
1.58
9.10
5.6
4.2
0.00
0.02
estimate
1.46
100
806
478
3891
1.54
8.34
5.6
4.2
0.00
0.00
estimate
0.50
105
860
472
3848
1.53
8.06
5.6
4.1
0.00
0.00
estimate
0.50
101
831
528
4439
1.52
7.58
5.3
4.9
6.85
6.72
mmol/l
0.74
501
4217
640
5648
1.59
7.07
9.4
8.6
80.41
79.46
u/l
0.21
615
5352
614
5407
1.53
6.47
5.9
4.5
13.30
12.89
mm/h
0.31
585
5023
23
71
3.30
6.32
1.4
1.3
—
—
—
0
0
313
2433
1.46
6.23
2.5
2.2
124.58
217.48
u/l
2.56
298
2309
417
3432
1.43
6.05
2.7
2.5
79.19
78.55
nmol/l
0.18
385
3067
363
2921
1.43
5.92
5.6
4.1
0.00
0.03
estimate
2.72
84
688
24
80
3.06
5.84
1.9
1.3
—
—
—
0
0
632
5653
1.50
5.68
5.2
4.5
15.02
14.90
pmol/l
0.57
584
5146
101
620
1.72
5.63
3.1
2.9
59.29
64.33
ml/min/173m2
0.64
38
273
551
4808
1.44
5.57
6.0
4.9
2148.38
2242.60
e6/l
—
8
82
747
6975
1.73
5.23
20.0
16.6
20.85
24.32
mg/l
2.30
626
5762
229
1728
1.45
5.15
5.6
4.4
1.02
1.02
kg/l
0.73
147
1183
72
418
1.79
4.88
5.0
3.6
44.06
46.19
%
0.29
72
408
407
3433
1.37
4.65
4.9
4.9
35.70
35.48
g/l
0.36
384
3231
468
4037
1.37
4.63
6.7
6.8
10.94
11.19
umol/l
0.14
445
3856
713
6631
1.55
4.48
6.4
5.6
1.85
1.96
mu/l
1.93
667
6093
459
3981
1.34
4.20
2.9
2.7
—
—
—
0
0
14
41
3.46
4.20
2.8
2.0
—
—
—
0
0
211
1624
1.40
4.14
1.8
1.6
0.72
1.35
mg/l
8.27
169
1282
298
2428
1.36
4.12
2.9
3.2
916.88
1218.68
ng/l
1.15
265
2085
127
897
1.49
3.94
7.8
7.3
—
—
—
0
0
527
4693
1.34
3.90
3.9
3.3
50.07
49.03
u/l
0.12
496
4396
186
1416
1.40
3.87
1.5
1.3
37.22
34.66
iu/ml
0.08
70
442
174
1316
1.41
3.75
1.5
1.3
8.14
10.68
u/ml
0.22
75
502
126
898
1.48
3.73
2.3
2.3
136.20
128.80
ug/g
0.11
101
716
207
1617
1.37
3.68
1.7
1.8
107182793.05
18913315.36
pmol/l
0.79
181
1343
43
234
1.88
3.63
1.7
1.5
238.77
283.94
ug/g
0.87
27
147
35
180
1.99
3.48
1.7
1.2
4.68
1.11
u/ml
—
5
11
410
3575
1.29
3.29
12.7
15.1
1.21
1.24
inr
0.58
356
2971
39
214
1.86
3.23
1.7
1.2
8.20
3.15
u/ml
—
6
20
48
283
1.74
3.16
1.6
1.2
0.50
1.48
u/ml
—
7
21
757
7236
1.55
3.07
22.4
20.1
3.97
3.97
mmol/l
0.01
744
7083
38
214
1.81
2.93
1.7
1.3
2.67
3.05
u/ml
—
9
32
755
7226
1.52
2.89
22.5
19.9
139.53
139.73
mmol/l
1.35
742
7086
439
3917
1.26
2.72
8.9
7.1
1.22
1.21
mmol/l
1.46
393
3392
397
3515
1.25
2.58
2.8
2.8
—
—
estimate
—
0
0
68
464
1.51
2.53
2.5
2.4
30.30
22.93
au/ml
—
5
35
227
1888
1.28
2.51
3.1
2.8
329.04
340.33
umol/l
1.01
200
1664
12
45
2.69
2.46
1.1
1.1
—
10.62
—
0
13
382
3381
1.24
2.45
3.2
3.0
103.42
128.87
ug/l
2.82
359
3133
64
436
1.51
2.41
4.5
2.4
1.37
1.24
%
0.44
64
431
163
1306
1.31
2.39
3.7
2.9
1.42
1.25
e6/l
0.18
107
702
33
192
1.75
2.33
2.3
1.6
8374.96
15621.55
e6/l
0.81
26
140
36
215
1.71
2.32
4.0
3.2
1.53
1.59
mmol/l
0.14
36
209
9
28
3.24
2.31
2.0
2.4
40.53
40.70
g/l
—
9
28
311
2712
1.24
2.24
3.0
3.5
2.35
2.36
mmol/l
0.62
281
2458
29
165
1.79
2.21
1.6
1.2
39.08
45.36
u/ml
—
6
23
65
454
1.47
2.19
2.1
1.8
—
—
—
0
0
40
251
1.62
2.16
2.9
2.9
—
—
—
0
0
769
7443
1.47
2.16
25.5
22.1
77.25
76.67
umol/l
0.20
760
7352
65
456
1.46
2.15
1.3
1.2
143.59
175.42
u/ml
0.21
59
419
11
42
2.64
2.15
1.0
1.0
—
—
—
0
0
88
653
1.39
2.14
1.9
2.4
3.33
7.27
ug/l
4.14
73
580
39
244
1.63
2.14
1.3
1.3
—
—
—
0
0
32
190
1.71
2.13
2.2
2.3
286.87
96.88
ug/min
0.72
15
109
70
502
1.43
2.07
2.2
1.9
—
—
—
0
0
54
773
0.68
2.06
2.9
3.5
—
—
—
0
0
134
1067
1.31
2.06
1.6
1.5
—
—
—
0
0
44
287
1.56
2.05
1.9
1.6
0.31
0.35
mg/l
0.16
16
132
14
63
2.24
2.01
1.3
1.1
108.64
108.95
pmol/l
0.01
14
63
58
405
1.46
1.98
1.5
1.5
—
—
—
0
0
261
2263
1.22
1.94
1.7
1.7
21.60
20.59
nmol/l
0.48
224
1890
5
11
4.57
1.94
1.4
1.3
—
—
—
0
0
123
976
1.31
1.94
1.9
1.8
—
—
—
0
0
314
2775
1.21
1.93
4.8
4.1
109.98
116.78
e6/l
0.04
235
1976
202
1706
1.24
1.92
3.0
2.7
5.20
6.32
e6/l
0.51
186
1564
778
7567
1.48
1.90
30.2
25.5
91.40
91.38
fl
0.06
773
7489
778
7567
1.48
1.90
30.3
25.5
252.71
250.41
e9/l
0.46
768
7421
727
6997
1.32
1.88
5.7
5.3
4.60
4.64
mmol/l
0.47
680
6487
778
7569
1.47
1.88
30.6
26.0
40.23
40.03
%
0.59
773
7486
778
7569
1.47
1.88
30.3
25.5
4.44
4.44
e12/l
0.09
768
7396
239
2066
1.22
1.82
4.6
3.6
0.00
0.01
estimate
1.24
89
651
389
3522
1.20
1.82
8.2
6.4
1.22
1.21
mmol/l
0.36
357
3235
158
1306
1.26
1.81
2.0
1.9
—
—
—
0
0
15
73
2.07
1.81
1.1
1.3
35.61
32.28
u/l
—
9
64
9
35
2.59
1.80
1.2
3.6
658.67
897.57
u/ml
—
9
35
7
23
3.06
1.80
1.0
1.1
—
—
—
0
0
737
7116
1.33
1.78
6.5
6.1
2.64
2.69
mmol/l
0.69
686
6571
279
2453
1.21
1.78
4.0
3.4
84.81
83.23
e6/l
0.01
229
1900
761
7386
1.38
1.75
14.9
12.7
25.81
24.92
u/l
0.94
743
7169
171
1439
1.24
1.68
1.6
1.4
2.31
2.46
g/l
0.60
108
863
701
6737
1.27
1.66
7.4
6.7
39.75
39.65
mmol/mol
0.12
661
6295
241
2103
1.21
1.65
3.9
3.3
0.39
0.50
e6/l
0.31
185
1563
32
205
1.58
1.64
1.9
1.3
—
—
—
0
0
721
6958
1.28
1.62
5.5
5.2
1.51
1.50
mmol/l
0.31
672
6406
86
669
1.32
1.59
3.3
2.7
67.72
66.81
g/l
0.61
80
618
6
20
3.01
1.58
1.0
1.1
—
—
—
0
0
601
5696
1.20
1.57
26.1
21.9
331.62
331.45
g/l
0.17
596
5664
11
50
2.22
1.57
1.0
1.1
220.27
225.07
mg/l
0.09
11
42
23
137
1.70
1.56
1.4
1.2
—
—
—
0
0
75
574
1.34
1.55
1.6
1.4
—
—
—
0
0
227
1983
1.20
1.53
2.4
2.3
2.87
2.99
mg/l
0.33
206
1700
54
393
1.40
1.52
6.3
3.6
1.02
1.02
ratio
0.56
48
367
187
1605
1.21
1.52
2.7
2.9
2.45
2.46
mmol/l
1.08
170
1444
25
155
1.63
1.48
2.2
3.0
11.43
9.16
pmol/l
0.39
25
155
79
618
1.31
1.42
4.3
3.7
107.41
84.98
ng/l
0.56
62
543
33
479
0.68
1.41
7.0
7.8
26.21
24.82
mmol/l
1.93
33
474
10
46
2.19
1.40
1.7
1.2
—
—
—
0
0
79
621
1.30
1.38
4.2
3.9
1.23
1.23
mmol/l
0.06
71
528
35
240
1.48
1.37
1.9
1.6
—
—
—
0
0
73
570
1.31
1.34
1.8
1.6
—
—
—
0
0
106
876
1.24
1.25
2.5
2.8
7.38
8.74
umol/l
0.33
92
783
41
296
1.41
1.25
1.9
1.9
—
—
—
0
0
368
3392
1.15
1.24
2.3
2.1
96.58
96.99
pmol/l
0.05
193
1747
111
923
1.23
1.24
2.0
1.9
—
—
—
0
0
42
305
1.40
1.24
2.0
2.0
4.32
7.76
iu/ml
0.73
15
76
33
229
1.46
1.23
1.6
1.5
20.00
0.08
iu/ml
—
5
45
19
116
1.65
1.22
1.3
1.6
—
—
—
0
0
31
213
1.47
1.22
1.5
1.5
—
—
—
0
0
18
110
1.65
1.16
1.1
1.0
—
—
—
0
0
5
20
2.51
1.15
1.2
1.3
0.31
0.27
g/l
—
5
15
26
175
1.50
1.14
1.6
1.3
—
—
—
0
0
26
175
1.50
1.14
4.7
3.3
7.10
7.69
mmol/l
0.84
26
170
124
1053
1.21
1.14
7.5
5.2
1.01
1.03
mmol/l
0.28
119
963
10
52
1.93
1.06
1.0
1.3
—
—
—
0
0
10
52
1.93
1.06
1.0
1.3
—
—
—
0
0
11
60
1.84
1.03
2.2
2.3
650.40
577.50
ml
—
5
36
7
34
2.07
1.03
1.3
1.4
—
—
—
0
0
152
1329
1.18
1.02
2.7
2.5
12.21
12.81
umol/l
0.53
141
1238
12
68
1.78
1.01
1.1
1.2
—
—
—
0
0
602
5789
1.15
0.99
22.0
20.8
13.73
13.70
%
0.25
594
5718
10
54
1.86
0.97
1.0
1.8
57.37
87.05
ng/l
—
10
54
686
6665
1.17
0.96
5.0
4.4
1.31
1.27
mmol/l
0.52
636
6083
34
251
1.37
0.95
1.4
1.5
—
—
—
0
0
35
260
1.36
0.94
1.8
1.6
6.10
10.94
u/ml
—
10
44
6
27
2.23
0.93
1.5
1.8
79.67
1090.59
nmol/24h
—
6
27
131
1141
1.18
0.93
2.5
2.5
21.14
22.29
%
0.49
120
1066
93
786
1.21
0.92
5.2
3.2
2.08
1.98
mmol/l
0.12
83
673
37
279
1.34
0.92
1.9
1.8
—
—
—
0
0
62
502
1.25
0.91
1.3
1.2
167.10
140.44
u/ml
0.16
22
203
6
28
2.15
0.91
1.2
1.1
—
—
—
0
0
707
6892
1.18
0.91
5.8
5.4
5.93
5.98
mmol/l
0.51
654
6286
44
341
1.31
0.91
1.0
1.0
—
—
—
0
0
139
1224
1.16
0.87
2.6
2.5
2.38
2.31
g/l
1.05
129
1136
63
759
0.82
0.81
1.7
1.8
1.48
1.51
%
0.17
58
659
269
2488
1.12
0.81
3.5
3.5
31.63
32.18
u/l
0.11
257
2356
56
456
1.24
0.81
3.5
3.4
4.49
4.53
pmol/l
0.10
48
404
8
47
1.71
0.81
1.6
1.3
6.39
6.29
u/l
—
8
41
101
873
1.18
0.80
3.5
4.4
11.36
24.41
ug/l
0.60
81
724
145
1290
1.15
0.80
1.7
1.8
1225.34
1206.47
nmol/l
0.07
122
969
185
1677
1.13
0.77
1.5
1.3
2.84
1.62
u/ml
0.36
53
458
11
67
1.65
0.75
4.4
5.5
23.00
41.87
u/ml
—
5
20
88
757
1.18
0.75
2.0
2.1
356.74
380.33
nmol/l
0.59
81
705
5
24
2.09
0.74
1.0
1.0
—
—
—
0
0
9
55
1.64
0.73
1.0
1.1
—
—
—
0
0
7
40
1.76
0.71
1.1
1.5
227.67
168.50
pmol/l
—
7
40
9
57
1.59
0.71
1.1
1.1
—
—
—
0
0
9
57
1.59
0.71
1.1
1.1
—
—
—
0
0
15
102
1.48
0.68
1.2
2.0
8.14
10.67
mmol/l
3.08
15
102
39
312
1.26
0.67
1.4
1.3
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
17
234
0.72
0.63
3.0
2.4
0.43
0.36
iu/ml
—
8
125
125
1124
1.13
0.61
1.4
1.4
—
—
—
0
0
160
1461
1.12
0.61
4.1
4.0
57.53
351.21
ng/l
4.15
119
1152
698
6844
1.13
0.60
18.1
16.4
78.54
78.60
ml/min/173m2
0.03
659
6377
13
186
0.69
0.60
1.3
1.1
1.56
1.56
g/l
0.00
13
186
0
22
0.00
0.59
0.0
1.3
—
0.78
—
0
16
29
228
1.28
0.59
1.2
1.3
—
—
—
0
0
10
64
1.57
0.58
1.1
1.1
—
—
—
0
0
0
23
0.00
0.58
0.0
1.1
—
—
—
0
0
0
23
0.00
0.58
0.0
1.2
—
—
—
0
0
0
23
0.00
0.58
0.0
1.2
—
—
—
0
0
29
229
1.28
0.57
2.0
1.7
—
—
—
0
0
6
36
1.67
0.56
3.7
2.3
—
—
—
0
0
11
73
1.51
0.56
1.1
1.3
—
—
—
0
0
8
55
1.46
0.56
1.1
1.1
—
—
—
0
0
27
212
1.28
0.56
1.4
1.6
—
—
—
0
0
14
194
0.72
0.55
2.0
2.2
127.44
126.87
g/l
—
9
155
167
1539
1.11
0.54
4.7
4.6
23.27
21.76
%
0.61
87
775
6
38
1.58
0.54
1.7
1.3
—
—
—
0
0
14
99
1.42
0.54
1.0
1.2
—
—
—
0
0
52
443
1.19
0.53
2.8
3.2
1.96
1.95
mmol/l
0.00
35
333
13
91
1.44
0.53
1.2
1.1
5.05
1.75
u/ml
—
8
45
25
196
1.28
0.53
1.3
1.1
—
—
—
0
0
132
1204
1.11
0.52
3.8
3.1
1.58
2.68
e6/l
1.77
74
598
55
472
1.18
0.52
1.4
1.6
—
—
—
0
0
77
679
1.15
0.52
6.6
6.8
9.84
9.81
mmol/l
0.01
72
648
9
64
1.41
0.51
2.1
1.6
—
—
—
0
0
6
41
1.47
0.50
1.2
1.4
30.33
31.14
umol/l
—
6
35
18
136
1.33
0.49
1.2
1.3
—
—
—
0
0
18
136
1.33
0.49
1.2
1.3
—
—
—
0
0
15
200
0.75
0.48
1.3
1.2
0.91
0.92
g/l
0.08
15
200
21
164
1.29
0.47
2.4
3.4
0.78
0.81
nmol/l
0.12
15
134
286
2722
1.08
0.46
3.5
3.4
6.72
7.19
mmol/l
1.11
243
2306
206
1942
1.08
0.42
5.6
5.5
1.69
3.00
ug/l
1.87
193
1733
24
194
1.24
0.42
1.3
1.1
—
—
—
0
0
5
32
1.57
0.42
1.0
1.0
—
—
—
0
0
6
95
0.63
0.42
1.0
1.2
—
2.50
—
0
28
40
342
1.18
0.41
2.3
1.7
1.60
1.54
g/l
0.16
33
307
0
15
0.00
0.41
0.0
1.5
—
6.07
—
0
9
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
80.33
—
0
9
0
16
0.00
0.41
0.0
1.2
—
1.64
—
0
10
0
17
0.00
0.40
0.0
1.1
—
97.00
—
0
10
59
662
0.88
0.38
2.3
2.1
3.73
3.41
ratio
0.90
48
534
32
272
1.18
0.36
2.3
1.9
—
—
—
0
0
198
1877
1.07
0.36
2.6
2.3
—
—
—
0
0
22
181
1.22
0.34
1.1
1.7
—
—
—
0
0
6
88
0.68
0.33
1.0
1.2
121.50
120.49
%
—
6
83
11
83
1.33
0.32
1.0
1.2
—
—
—
0
0
38
333
1.15
0.31
3.6
3.5
26.16
4291.19
u/ml
0.85
31
297
7
52
1.35
0.31
1.3
1.6
206.71
292.49
mu/l
—
7
39
44
494
0.88
0.31
1.8
1.9
3.70
3.51
mmol/l
0.42
34
366
17
206
0.82
0.29
2.1
1.7
97.24
92.45
%
0.58
17
200
10
76
1.32
0.28
1.7
2.3
—
—
—
0
0
8
65
1.23
0.27
1.0
1.1
—
—
—
0
0
28
243
1.16
0.27
5.5
3.4
2.03
3.53
ratio
0.48
22
143
62
569
1.10
0.26
2.9
3.0
148.78
208.14
ng/l
1.06
49
525
5
74
0.67
0.26
1.2
1.8
—
—
—
0
0
301
3098
0.96
0.24
1.9
1.9
1.39
1.34
mmol/l
0.47
253
2589
24
208
1.16
0.24
1.8
1.9
7.76
4.47
iu/l
—
10
83
5
40
1.25
0.22
4.0
3.0
0.60
0.92
index
—
5
40
275
2671
1.04
0.22
4.1
4.1
15.75
7.76
mg/mmol
0.84
177
1618
22
191
1.16
0.22
1.7
1.6
—
—
—
0
0
14
167
0.84
0.21
1.1
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
28.70
—
0
9
13
110
1.18
0.17
1.2
1.4
—
—
—
0
0
7
63
1.11
0.17
1.1
1.0
—
—
—
0
0
22
196
1.13
0.16
1.3
1.7
—
—
—
0
0
8
71
1.13
0.16
1.0
1.1
—
—
—
0
0
21
187
1.13
0.16
1.5
1.3
272.00
237.56
miu/ml
—
7
83
19
168
1.13
0.16
1.2
1.2
11.79
20.68
e6/l
0.34
19
119
8
73
1.10
0.15
1.0
1.1
—
—
—
0
0
25
226
1.11
0.15
1.9
1.6
—
—
—
0
0
11
129
0.85
0.14
1.0
1.9
—
—
—
0
0
19
169
1.13
0.14
1.2
1.3
1518.58
813.11
e6/l
0.17
19
126
192
1873
1.03
0.13
3.5
4.0
91.85
89.74
%
0.60
183
1834
15
169
0.89
0.12
2.3
3.5
24.63
27.98
mg/l
—
8
110
117
1136
1.03
0.11
3.0
3.3
0.63
0.78
ug/l
2.25
80
754
5
46
1.09
0.09
1.4
1.1
—
—
—
0
0
73
704
1.04
0.09
3.1
2.4
34.14
35.92
u/l
0.17
63
594
13
145
0.89
0.09
1.3
1.6
—
—
—
0
0
5
48
1.04
0.09
4.6
1.8
—
—
—
0
0
94
968
0.97
0.09
5.1
5.0
32.49
32.43
%
0.02
67
624
6
54
1.11
0.09
1.5
1.2
9.50
12.75
u/l
—
6
48
6
57
1.05
0.08
2.8
2.2
13.67
13.21
%
—
6
57
7
66
1.06
0.08
1.3
1.7
—
—
—
0
0
7
66
1.06
0.08
1.3
1.7
—
—
—
0
0
7
66
1.06
0.08
1.3
1.7
—
—
—
0
0
8
75
1.07
0.07
1.0
2.0
—
—
—
0
0
12
108
1.11
0.07
1.2
1.4
—
—
—
0
0
10
112
0.89
0.07
4.4
5.9
291.40
369.86
umol/l
—
10
101
15
163
0.92
0.07
1.9
1.6
—
—
—
0
0
8
92
0.87
0.06
1.0
1.1
—
—
—
0
0
12
131
0.91
0.05
1.4
1.5
—
—
—
0
0
21
198
1.06
0.05
2.1
1.3
—
—
—
0
0
12
110
1.09
0.05
1.2
1.4
—
—
—
0
0
92
904
1.02
0.04
8.9
7.6
1.47
0.94
mmol/l
0.99
76
753
24
251
0.95
0.04
2.1
1.8
3.69
3.80
mg/l
0.03
18
191
90
914
0.98
0.03
9.1
7.6
5.13
5.14
kpa
0.03
84
881
90
914
0.98
0.03
9.1
7.6
11.94
12.33
kpa
0.38
84
884
11
103
1.07
0.02
1.7
1.5
29.85
33.08
g/l
0.42
11
93
49
482
1.02
0.01
2.5
2.4
13.48
13.16
nmol/l
0.08
39
431
11
104
1.06
0.01
1.7
1.5
0.80
0.96
ratio
—
6
65
11
104
1.06
0.01
1.7
1.4
—
—
—
0
0
11
104
1.06
0.01
1.7
1.5
1.09
1.24
ratio
—
6
65
11
104
1.06
0.01
1.7
1.5
1.10
1.13
ratio
—
6
65
10
106
0.94
0.01
1.6
1.5
0.73
17.50
nmol/l
—
10
101
15
153
0.98
0.00
1.1
2.1
7.97
3197.11
u/l
—
8
54
20
203
0.98
0.00
2.9
3.1
1.31
2.05
index
0.43
13
110
21
213
0.99
0.00
1.2
1.3
—
—
—
0
0
11
108
1.02
0.00
1.2
1.4
—
—
—
0
0
11
108
1.02
0.00
1.2
1.4
—
—
—
0
0
12
122
0.98
0.00
1.2
1.6
—
—
—
0
0
10
99
1.01
0.00
1.0
1.7
—
—
—
0
0
11
109
1.01
0.00
1.2
1.4
—
—
—
0
0
15
151
0.99
0.00
1.4
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
7.9
—
—
—
0
0
(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
8
81
0.99
-0.00
1.6
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
86
0.93
-0.00
1.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
94
0.96
-0.00
1.2
1.4
0.20
0.19
nmol/l
—
9
71
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
86
0.93
-0.00
1.9
3.7
50.30
102.80
u/ml
—
8
86
0
7
0.00
-0.00
0.0
1.0
—
117.86
—
0
7
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
80
1.00
-0.00
2.4
3.7
—
—
—
0
0
8
86
0.93
-0.00
1.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
17
170
1.00
-0.00
1.4
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_CONJUNCTDEGDEPOT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CONJUNCTDEGDEPOT | 1.186 [1.08, 1.3] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.208 |
During the follow-up period (1.1.1998 — 31.12.2019), 778 out of 3296 females with H7_CONJUNCTDEGDEPOT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CONJUNCTDEGDEPOT | 1.055 [0.94, 1.19] | 0.384 |
| Birth year | 0.986 [0.98, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 474 out of 1823 males with H7_CONJUNCTDEGDEPOT died.
Mortality risk
Mortality risk for people of age
years, who have H7_CONJUNCTDEGDEPOT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.14% | 0.185% |
| 5 | 0.716% | 1.11% |
| 10 | 1.788% | 3.068% |
| 15 | 3.429% | 5.735% |
| 20 | 5.936% | 9.686% |
Relationships between endpoints
↥Index endpoint: H7_CONJUNCTDEGDEPOT – conjunctival degenerations and deposits
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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