This is a non-core endpoint: only basic statistics are computed.
Abnormal reflex
R18_ABNORMAL_REFLEX
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
205 |
4. Check minimum number of eventsNone |
205 |
5. Include endpointsNone |
205 |
6. Filter based on genotype QC (FinnGen only) |
190 |
Control definitions (FinnGen only)
- Control exclude
- CD2_BENIGN_FEMALE_GEN_OTH
Extra metadata
- Level in the ICD hierarchy
- 4
- Special
- INCREASEDREFLEXES
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- R29
- Name in latin
- Reflexus abnormis
Similar endpoints
↥List of similar endpoints to
Abnormal reflex
based on the number of shared cases.
Similar with more cases:
- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
- Any operation in hilmo
- Any prescribed medicine buy
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 190 | 113 | 77 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | 50.43 | 45.49 | 57.68 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 194
- Matched controls
- 1940
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R29.2
ICD-10 Finland
Abnormal reflex
+∞
277.5
193
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
10.9
49.5
65
86
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
8.7
29.3
42
60
TAB00
NOMESCO Finland
Lumbar puncture
6.7
15.2
26
44
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
14.2
14.3
24
19
R20.2
ICD-10 Finland
Paraesthesia of skin
4.1
10.1
31
87
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
10.9
9.8
18
18
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.7
9.4
33
102
Z01.9
ICD-10 Finland
Special examination, unspecified
4.5
9.0
23
56
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.4
8.9
35
117
N03AX12
ATC
[U] gabapentin; oral
2.9
8.6
48
197
AA1AD
NOMESCO Finland
CT of head and brain
2.6
8.4
68
338
J45.9
ICD-10 Finland
Asthma, unspecified
2.7
8.1
51
223
SPAT1229
SPAT
Assessment of need for aid
4.4
7.7
20
49
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.2
7.5
33
118
X59
ICD-10 Finland
Exposure to unspecified factor
2.6
7.3
52
240
R51.80
ICD-10 Finland
Headache
2.7
7.2
47
208
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.2
6.9
30
106
SPAT1260
SPAT
Consultation of another employee
2.6
6.7
44
195
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.6
6.7
23
70
L12
ICPC
Hand/finger symptom/complaint
2.6
6.6
46
210
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.9
6.5
20
56
N06AX21
ATC
duloxetine; oral
2.9
6.3
33
130
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
22
40
6.08
11.94
6.6
2.6
5.04
5.05
kpa
0.02
22
40
39
123
3.72
10.86
4.2
3.8
1.22
1.22
mmol/l
0.43
31
108
19
40
5.16
8.79
1.3
1.2
1.55
18.25
e6/l
0.54
11
32
44
170
3.05
8.78
5.3
3.4
—
—
—
0
0
33
114
3.28
7.90
5.8
6.7
25.29
25.17
mmol/l
0.06
33
114
66
334
2.48
7.72
1.9
1.7
119231210.67
40767014.97
pmol/l
0.27
52
287
135
943
2.42
7.41
5.1
4.7
6.52
6.53
mmol/l
0.03
128
885
51
238
2.55
7.01
2.0
1.6
1583.53
1225.87
nmol/l
1.39
34
181
68
392
2.13
5.59
2.1
1.7
0.69
1.39
mg/l
2.22
51
322
102
686
2.03
5.50
5.4
3.7
0.16
0.04
estimate
0.56
44
164
106
725
2.02
5.43
2.5
2.6
77.55
74.98
nmol/l
0.39
98
664
11
15
7.70
5.22
1.1
1.1
—
—
—
0
0
122
894
1.98
4.95
6.4
6.3
9.92
11.21
umol/l
1.20
114
858
11
18
6.41
4.67
1.1
1.2
—
—
—
0
0
121
895
1.94
4.65
5.2
3.8
0.00
8.59
estimate
0.50
45
189
110
789
1.91
4.64
7.4
7.1
1.21
1.21
mmol/l
0.05
85
684
66
400
1.99
4.61
2.4
2.1
2.66
2.73
mg/l
0.11
52
353
119
890
1.87
4.27
5.2
3.7
0.00
0.01
estimate
0.50
47
187
78
514
1.87
4.17
5.7
3.9
0.00
0.02
estimate
0.74
42
179
80
534
1.85
4.09
3.2
2.6
47.74
55.78
u/l
2.18
69
505
120
909
1.84
4.04
5.2
3.8
0.00
0.00
estimate
-0.00
47
178
68
438
1.85
3.85
1.4
1.4
0.63
1.51
u/ml
1.48
24
126
99
719
1.77
3.73
5.8
4.5
36.72
36.18
g/l
0.47
90
689
72
476
1.82
3.73
3.7
2.7
0.58
0.39
e6/l
0.27
57
341
76
515
1.78
3.60
5.2
3.0
0.07
0.01
estimate
0.54
42
150
98
720
1.73
3.47
7.7
6.1
1.21
1.21
mmol/l
1.00
89
673
20
84
2.54
3.35
1.3
1.4
—
—
—
0
0
9
19
4.91
3.28
1.1
1.2
—
—
—
0
0
6
8
7.69
3.07
6.2
3.1
—
—
—
0
0
6
8
7.69
3.07
5.8
2.5
18.00
10.50
%
—
6
8
16
63
2.68
3.04
1.5
1.5
—
—
—
0
0
173
1534
2.18
2.95
6.7
5.2
1.61
1.90
mu/l
4.03
166
1428
84
615
1.65
2.86
5.5
4.0
39.57
40.99
ng/l
0.03
65
405
45
278
1.81
2.83
2.5
2.4
14.87
13.47
umol/l
0.58
40
260
44
275
1.78
2.66
3.1
3.2
0.82
0.81
mmol/l
0.13
36
263
49
317
1.73
2.63
2.3
2.6
2.41
2.45
mmol/l
1.92
44
285
14
56
2.62
2.59
2.9
2.0
25.72
24.46
mmol/l
0.59
14
56
6
11
5.59
2.56
1.2
1.0
—
—
—
0
0
41
254
1.78
2.55
2.6
2.4
2.28
2.34
g/l
0.26
36
235
36
215
1.83
2.52
7.2
5.8
1.07
1.03
mmol/l
0.50
30
198
7
16
4.50
2.50
1.0
1.1
—
—
—
0
0
150
1293
1.71
2.49
6.0
4.3
15.31
14.60
pmol/l
3.11
142
1198
24
125
2.05
2.49
1.9
1.5
19.43
24.37
iu/l
0.40
19
107
34
201
1.84
2.45
1.6
1.7
—
—
—
0
0
17
78
2.29
2.39
1.4
1.8
—
—
—
0
0
31
182
1.84
2.29
2.9
2.9
5.74
6.73
umol/l
0.35
25
162
32
190
1.82
2.28
1.7
1.7
—
—
—
0
0
65
469
1.58
2.26
2.8
3.3
1395.52
935.35
ng/l
0.35
52
382
173
1570
1.94
2.20
5.2
4.9
5.77
5.84
mmol/l
0.48
162
1462
89
693
1.53
2.19
2.1
2.0
88.25
97.34
pmol/l
1.36
53
360
119
987
1.53
2.17
8.2
9.8
3.77
4.09
e9/l
1.21
106
857
180
1658
2.19
2.16
21.5
14.5
22.16
22.01
mg/l
0.02
152
1373
16
75
2.24
2.15
4.3
2.7
0.54
0.68
%
1.53
16
75
38
242
1.71
2.14
2.4
2.4
25.46
23.35
%
0.42
33
228
148
1293
1.61
2.10
9.4
7.8
76.91
79.18
u/l
0.32
141
1227
13
56
2.42
2.10
1.8
1.3
—
—
—
0
0
40
260
1.68
2.09
1.9
1.9
—
—
—
0
0
7
21
3.42
1.98
1.1
1.4
—
—
—
0
0
11
45
2.53
1.97
2.7
2.6
8.88
8.48
kpa
0.34
11
45
147
1290
1.58
1.96
5.6
4.0
10.46
10.48
mm/h
0.01
141
1212
6
16
3.83
1.95
3.5
3.6
1.18
1.19
mmol/l
—
6
16
6
16
3.83
1.95
3.5
3.6
102.33
107.81
mmol/l
—
6
16
37
244
1.64
1.83
2.1
2.0
1.49
1.46
%
0.09
31
214
55
400
1.52
1.80
3.9
3.9
1.02
1.02
kg/l
0.43
35
269
100
827
1.43
1.68
4.4
3.0
96.15
105.11
ug/l
0.28
93
784
17
93
1.91
1.57
3.1
2.4
25.49
24.31
mmol/l
0.61
17
93
62
475
1.45
1.56
1.9
1.6
20.61
21.48
nmol/l
0.18
55
407
49
362
1.47
1.48
1.5
1.3
20.44
24.81
iu/ml
0.24
17
119
5
16
3.18
1.44
1.8
1.5
—
—
—
0
0
136
1209
1.42
1.41
4.6
3.2
47.18
44.67
u/l
0.16
124
1157
20
120
1.74
1.40
1.9
1.6
—
—
—
0
0
7
29
2.47
1.40
1.1
1.1
—
—
—
0
0
169
1573
1.58
1.31
19.8
14.0
85.16
84.16
ml/min/173m2
0.26
162
1457
6
24
2.55
1.31
1.7
1.5
—
—
—
0
0
54
417
1.41
1.28
2.6
2.7
315.62
342.51
umol/l
1.06
45
375
10
49
2.10
1.24
1.3
4.2
5000.40
68.82
mg/l
—
5
42
10
49
2.10
1.24
1.3
4.2
16.22
29.05
mg/l
—
5
42
8
38
2.15
1.20
1.6
1.3
—
—
—
0
0
5
20
2.54
1.16
1.2
1.3
—
—
—
0
0
21
311
0.64
1.15
2.5
3.0
0.64
0.76
ug/l
0.44
13
196
13
73
1.84
1.14
2.8
1.9
54.74
4285.83
u/l
—
5
23
10
51
2.01
1.13
1.4
1.1
—
7.74
—
0
7
165
1540
1.48
1.13
6.0
5.9
38.33
38.76
mmol/mol
0.32
153
1456
8
41
1.99
1.10
1.8
2.8
0.00
0.00
g/l
—
8
41
7
32
2.23
1.09
1.1
2.8
5.86
10.41
pmol/l
—
7
32
34
249
1.44
1.07
2.7
2.7
4.45
2.25
e6/l
0.45
16
109
174
1652
1.52
0.97
5.5
5.5
2.64
2.77
mmol/l
1.00
151
1550
42
326
1.37
0.96
1.4
1.3
1.25
7.47
u/ml
2.37
18
129
9
51
1.80
0.96
1.6
1.2
—
—
—
0
0
172
1631
1.48
0.94
4.8
5.0
4.57
4.68
mmol/l
0.70
152
1535
8
43
1.90
0.88
5.6
1.4
—
—
—
0
0
59
490
1.29
0.86
4.3
4.0
14.48
10.38
mg/mmol
0.16
34
308
165
1562
1.38
0.82
3.9
4.2
1.32
1.28
mmol/l
0.40
145
1450
6
32
1.90
0.82
1.3
1.8
—
—
—
0
0
171
1629
1.42
0.81
4.7
4.9
1.46
1.46
mmol/l
0.00
150
1524
23
170
1.40
0.71
2.9
3.9
2.48
34.39
ug/l
0.66
18
134
5
26
1.95
0.71
1.8
1.5
—
—
—
0
0
15
102
1.51
0.70
1.1
1.0
—
—
—
0
0
123
1135
1.23
0.67
3.8
3.5
—
—
—
0
0
35
281
1.30
0.66
3.1
2.5
1.43
0.97
e6/l
0.37
19
141
19
138
1.42
0.65
6.2
6.9
1.60
1.33
mmol/l
0.40
19
138
36
292
1.29
0.63
1.5
1.5
—
—
—
0
0
0
23
0.00
0.58
0.0
2.0
—
13.32
—
0
23
6
35
1.74
0.58
1.7
1.8
—
—
—
0
0
17
124
1.41
0.58
4.7
3.7
114.98
82.69
ng/l
0.55
12
111
87
785
1.20
0.57
2.7
2.6
—
—
estimate
—
0
0
9
60
1.52
0.55
1.2
1.3
—
2.28
—
0
12
9
61
1.50
0.54
2.9
3.3
10.78
733.31
u/ml
—
9
51
181
1760
1.42
0.54
14.1
11.1
26.61
25.93
u/l
0.26
174
1724
14
100
1.43
0.53
1.3
1.4
—
—
—
0
0
17
127
1.37
0.51
1.4
1.2
194.90
130.69
u/ml
—
8
52
7
49
1.44
0.46
1.3
1.3
—
—
—
0
0
8
58
1.40
0.42
1.6
1.6
—
—
—
0
0
0
18
0.00
0.40
0.0
1.7
—
—
—
0
0
0
18
0.00
0.40
0.0
1.7
—
—
—
0
0
0
18
0.00
0.40
0.0
1.7
—
—
—
0
0
5
35
1.44
0.39
1.2
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
15
117
1.31
0.36
2.0
1.9
—
—
—
0
0
6
44
1.38
0.34
1.2
1.5
—
—
—
0
0
34
387
0.85
0.32
2.4
2.2
—
—
—
0
0
7
52
1.36
0.31
1.1
1.3
—
66.76
—
0
7
17
201
0.83
0.25
2.1
2.0
3.47
3.49
ratio
0.03
11
165
34
304
1.14
0.25
5.2
3.3
163.29
221.18
ng/l
0.17
24
218
15
124
1.23
0.24
1.7
1.4
—
—
—
0
0
5
37
1.36
0.23
1.2
1.6
—
—
—
0
0
13
156
0.82
0.22
1.9
1.7
3.40
3.61
mmol/l
—
7
114
0
11
0.00
0.21
0.0
1.7
—
6.90
—
0
11
37
405
0.89
0.21
4.8
4.6
24.77
21.61
%
0.61
19
185
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
193.91
—
0
14
0
14
0.00
0.20
0.0
1.2
—
11.14
—
0
14
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
6
52
1.16
0.19
1.7
1.5
—
—
—
0
0
23
204
1.14
0.19
9.7
6.6
103.26
104.13
mmol/l
0.26
23
204
19
166
1.16
0.19
10.4
7.0
—
—
—
0
0
15
129
1.18
0.17
2.6
2.3
76.70
71.73
ml/min/173m2
—
10
59
75
715
1.08
0.17
2.1
1.9
1.24
1.39
mmol/l
0.99
55
617
5
66
0.75
0.17
2.0
2.1
—
—
—
0
0
5
66
0.75
0.17
2.6
1.5
—
—
—
0
0
16
143
1.13
0.12
2.2
2.0
—
—
—
0
0
26
241
1.09
0.11
2.2
2.1
—
—
—
0
0
24
223
1.09
0.09
2.3
2.0
—
—
—
0
0
6
54
1.11
0.09
1.7
1.6
—
—
—
0
0
6
57
1.05
0.08
1.0
1.1
—
—
—
0
0
6
57
1.05
0.08
1.0
1.1
—
—
—
0
0
6
57
1.05
0.08
3.0
2.7
—
—
—
0
0
35
364
0.95
0.05
1.6
1.7
—
—
—
0
0
51
502
1.02
0.01
4.8
5.1
1.96
1.91
ug/l
0.05
41
447
7
69
1.02
0.00
1.4
2.0
93.86
95.75
%
—
7
69
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.0
—
10.46
—
0
7
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.0
—
4.59
—
0
7
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
17.41
—
0
7
0
6
0.00
-0.00
0.0
2.2
—
—
—
0
0
5
49
1.02
-0.00
1.2
1.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
1.41
—
0
7
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: R18_ABNORMAL_REFLEX – Abnormal reflex
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).