obsolete_incontinentia pigmenti achromians: a dermal melanocytic condition affecting the shoulder area. Nevus of Ito often occurs in association with nevus of Ota in the same patient but is much less common, although the true incidence is unknown.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2013 |
4. Check minimum number of eventsNone |
2013 |
5. Include endpoints |
2050 |
6. Filter based on genotype QC (FinnGen only) |
1806 |
Control definitions (FinnGen only)
- Control exclude
- L12_OTHERSKINSUBCUTIS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L80-L99
- Name in latin
- Aliae perturbationes pigmentationis cutis
Similar endpoints
↥List of similar endpoints to
Other disorders of pigmentation
based on the number of shared cases.
Similar with more cases:
- Other disorders of skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 11936 | 7478 | 4395 |
| Only index persons | 10675 | 6915 | 3760 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.18 | 0.21 | 0.12 |
| Only index persons | 0.22 | 0.25 | 0.14 |
| Median age at first event (years) | |||
| Whole population | 54.72 | 57.66 | 49.93 |
| Only index persons | 57.01 | 58.69 | 53.92 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1806 | 1213 | 593 |
| Unadjusted period prevalence (%) | 0.38 | 0.43 | 0.27 |
| Median age at first event (years) | 61.25 | 59.64 | 64.55 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1900
- Matched controls
- 19000
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L81.4
ICD-10 Finland
Other melanin hyperpigmentation
653.4
307.7
879
25
L81.1
ICD-10 Finland
Chloasma
142.3
307.7
192
15
L81.7
ICD-10 Finland
Pigmented purpuric dermatosis
638.0
307.7
405
8
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
11.9
307.7
628
758
L57.0
ICD-10 Finland
Actinic keratosis
5.7
221.3
499
1109
L81.9
ICD-10 Finland
Disorder of pigmentation, unspecified
283.1
154.9
156
6
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
10.5
136.3
155
159
L81.8
ICD-10 Finland
Other specified disorders of pigmentation
349.4
129.2
129
*
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
5.2
123.7
286
632
XQ848
NOMESCO Finland
Dermatological photography
8.9
123.3
160
195
XQ845
NOMESCO Finland
Dermatoscopy
10.9
113.6
125
122
L82
ICD-10 Finland
Seborrhoeic keratosis
3.2
105.3
536
2058
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
22.6
103.2
76
35
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
7.9
83.4
117
156
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
7.1
81.6
126
187
ZXC50
NOMESCO Finland
Cryotherapy
6.8
80.4
131
206
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
3.6
74.5
279
871
R23.8
ICD-10 Finland
Other and unspecified skin changes
2.6
72.9
580
2756
L81.0
ICD-10 Finland
Postinflammatory hyperpigmentation
327.7
63.8
64
*
D03.31
ICD-10 Finland
Melanoma in situ in another or unspecified part of the face
23.0
61.7
45
20
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.5
60.4
519
2525
E0000UV, ,
ATC
2.1
54.9
911
5757
D07AC01
ATC
betamethasone; topical
2.1
49.9
785
4816
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
6.8
49.1
78
119
L81.3
ICD-10 Finland
Café au lait spots
+∞
47.1
45
*
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
14.3
46.0
42
30
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
3.2
45.2
192
642
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
7.9
43.5
60
78
QCA25
NOMESCO Finland
Destruction of lesion of skin of upper limb
14.7
43.4
39
27
TQW99
NOMESCO Finland
Other minor procedure on skin
3.6
42.4
146
427
D06BB10
ATC
imiquimod; topical
3.4
41.4
159
499
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
5.1
41.3
88
178
TQW80
NOMESCO Finland
Local dermatologic skincare
5.7
39.4
75
137
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
3.0
39.4
188
671
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
4.4
36.2
93
220
ZXC15
NOMESCO Finland
Use of photodynamic technique
7.1
36.1
55
80
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
3.3
35.5
140
446
D07AD01
ATC
clobetasol; topical
2.2
34.9
356
1816
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
4.5
34.6
85
194
QXE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in uspecified region
10.5
34.3
38
37
127
Kela drug reimbursment
Transplant complication
7.3
34.0
50
70
D07AB02
ATC
hydrocortisone butyrate; topical
1.9
33.6
615
3854
S18
ICPC
Laceration/cut
1.7
29.7
938
6840
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
2.9
29.5
147
536
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
7.9
27.7
38
49
L04AA06
ATC
mycophenolic acid; systemic
5.5
26.7
52
97
S29
ICPC
Skin symptom/complaint other
1.9
26.7
434
2591
L81.2
ICD-10 Finland
Freckles
+∞
26.1
25
*
Z94.0
ICD-10 Finland
Kidney transplant status
8.2
25.7
34
42
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
25.2
468
2903
L04AA01
ATC
[U] ciclosporin
5.8
25.1
46
81
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
3.7
24.9
79
218
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
24.7
587
3908
SPAT1153
SPAT
Removal of sutures
1.7
24.3
616
4168
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
4.5
23.9
58
131
L81
ICD-10 Finland
Other disorders of pigmentation
126.6
23.6
25
*
L04AD01
ATC
ciclosporin; systemic
4.7
23.4
54
117
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
23.2
467
2957
UJF32
NOMESCO Finland
Coloscopy
1.7
23.0
518
3385
QXA50
NOMESCO Finland
Skin cryotherapy, unspecified location
9.2
23.0
28
31
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
22.7
704
5002
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
22.0
276
1503
L01BC02
ATC
fluorouracil; systemic, topical
7.5
21.7
31
42
D69.0
ICD-10 Finland
Allergic purpura
7.7
20.8
29
38
S08
ICPC
Skin colour change
2.5
20.8
134
556
D07AB08
ATC
desonide; topical
2.1
20.8
215
1091
ZXC20
NOMESCO Finland
Use of chemical agents
4.1
20.7
57
142
E000006, ,
ATC
2.4
20.6
144
621
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
4.4
20.2
51
119
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
3.5
20.1
71
211
C44.71
ICD-10 Finland
Basocellular carcinoma of the skin of the lower extremity including the hip
6.0
20.0
35
59
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
7.1
20.0
30
43
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
58.2
19.9
23
*
J01DB01
ATC
cefalexin; oral
1.7
19.8
1538
13466
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
8.2
19.7
26
32
L91.0
ICD-10 Finland
Hypertrophic scar
16.6
19.6
31
19
A02BC05
ATC
esomeprazole; systemic
1.6
19.5
768
5726
D04.7
ICD-10 Finland
Carcinoma in situ: Skin of lower limb, including hip
8.4
19.3
25
30
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
3.4
19.2
71
217
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.6
18.9
113
452
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
18.9
847
6487
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
4.5
18.3
44
99
L04AX01
ATC
azathioprine; systemic
2.9
18.3
88
315
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.7
18.0
427
2806
SPAT1301
SPAT
No procedures
1.6
17.8
584
4152
S21
ICPC
Skin texture symptom/complaint
1.8
17.3
307
1858
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
3.4
17.3
61
181
H02AB06
ATC
prednisolone; systemic
1.5
17.3
875
6837
E000001, ,
ATC
1.7
17.0
363
2316
8742/2-C44.9
ICD-O-3
Lentigo maligna of skin, NOS
22.1
16.9
24
11
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
5.3
16.6
33
63
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
16.3
669
4981
D02AX
ATC
Other emollients and protectives
3.0
16.0
70
237
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
16.0
516
3641
M79.6
ICD-10 Finland
Pain in limb
1.5
15.9
829
6481
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
15.5
720
5487
D06BX02
ATC
ingenol mebutate; topical
4.6
15.4
36
79
L17
ICPC
Foot/toe symptom/complaint
1.5
15.4
579
4221
L85.3
ICD-10 Finland
Xerosis cutis
5.5
15.3
29
53
R03BA08
ATC
ciclesonide; inhalant
2.0
15.2
177
935
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.0
15.2
43
110
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
15.1
879
6998
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
2.1
15.0
140
681
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
14.1
15.0
25
18
D69.2
ICD-10 Finland
Other nonthrombocytopenic purpura
12.5
14.9
26
21
M25.5
ICD-10 Finland
Pain in joint
1.5
14.6
615
4579
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.8
14.5
44
118
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
14.4
235
1385
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
5.6
14.3
27
49
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.7
14.3
78
299
D10AX03
ATC
azelaic acid; topical
2.2
14.2
123
581
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
4.0
14.1
39
98
D07AC13
ATC
mometasone; topical
1.5
14.0
511
3685
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
14.0
245
1474
L84
ICD-10 Finland
Corns and callosities
3.1
13.9
57
186
N03AX12
ATC
[U] gabapentin; oral
1.7
13.9
300
1910
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
13.6
525
3830
N02AX02
ATC
tramadol; systemic, rectal
1.5
13.3
753
5920
J01MA02
ATC
ciprofloxacin; systemic
1.5
13.3
669
5144
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.9
13.3
177
979
L30.8
ICD-10 Finland
Other specified dermatitis
2.8
13.2
64
230
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
2.8
13.2
67
247
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
3.7
13.2
41
112
L30.0
ICD-10 Finland
Nummular dermatitis
2.6
13.1
78
312
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
12.9
333
2214
A02BC03
ATC
lansoprazole; oral
1.5
12.8
517
3800
A98
ICPC
Health maint/preventive medicine
2.5
12.8
1834
17430
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
12.6
1198
10309
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
12.5
523
3865
QDA25
NOMESCO Finland
Destruction of lesion of skin of lower limb
10.1
12.5
24
24
D02AE01
ATC
carbamide; topical
2.1
12.5
118
578
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
12.3
1300
11378
D04.4
ICD-10 Finland
Carcinoma in situ: Skin of scalp and neck
5.5
12.1
23
42
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
12.1
243
1515
R51.80
ICD-10 Finland
Headache
1.6
12.1
297
1950
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.3
12.1
88
387
SPAT1263
SPAT
Sampling
1.4
12.1
736
5837
S97
ICPC
Chronic ulcer skin
2.2
12.0
101
472
P01BA02
ATC
hydroxychloroquine; oral
1.9
11.9
152
829
A12AA04
ATC
calcium carbonate; oral
4.2
11.8
31
75
A02BC02
ATC
pantoprazole; systemic
1.4
11.8
1251
10912
G44.2
ICD-10 Finland
Tension-type headache
1.7
11.8
261
1670
L43.8
ICD-10 Finland
Other lichen planus
3.4
11.5
41
123
SPAT1312
SPAT
General health counselling
1.5
11.5
546
4128
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
3.5
11.4
39
114
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
11.4
665
5218
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
3.1
11.4
48
160
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.3
11.3
89
405
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.8
11.3
168
962
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
3.4
11.3
40
120
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.7
11.2
223
1386
L90.5
ICD-10 Finland
Scar conditions and fibrosis of skin
17.1
11.2
17
10
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
11.2
350
2430
R60.0
ICD-10 Finland
Localized oedema
1.7
11.1
236
1493
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
3.1
11.0
45
147
ZZR00
NOMESCO Finland
Flap of skin
3.1
11.0
45
147
B07.9
ICD-10 Finland
Verruca simplex
2.5
11.0
67
272
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
10.9
184
1092
J05AB11
ATC
valaciclovir; oral
1.6
10.9
266
1742
L50.3
ICD-10 Finland
Dermatographic urticaria
3.3
10.8
40
123
B01AB05
ATC
enoxaparin; parenteral
1.4
10.7
552
4224
F16
ICPC
Eyelid symptom/complaint
2.1
10.7
102
501
L14
ICPC
Leg/thigh symptom/complaint
1.8
10.7
157
895
R42
ICD-10 Finland
Dizziness and giddiness
1.5
10.7
425
3099
E000002, ,
ATC
1.7
10.5
183
1096
J02AC01
ATC
fluconazole; systemic
1.4
10.5
695
5554
L81.6
ICD-10 Finland
Other disorders of diminished melanin formation
+∞
10.4
10
*
L85.89
ICD-10 Finland
Other specified epidermal thickening
+∞
10.4
10
*
R06AX27
ATC
desloratadine; oral
1.4
10.4
499
3770
ULA02
NOMESCO Finland
Kolposcopy
1.8
10.4
154
881
L94.0
ICD-10 Finland
Localized scleroderma [morphea]
32.7
10.3
13
*
S82
ICPC
Naevus/mole
1.6
10.3
264
1748
B03XA01
ATC
erythropoietin; parenteral
4.9
10.3
22
45
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
4.0
10.2
28
70
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.4
10.2
601
4702
M54.5
ICD-10 Finland
Low back pain
1.4
10.1
658
5235
R05
ICD-10 Finland
Cough
1.5
10.1
384
2770
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
10.1
722
5835
C10AA03
ATC
pravastatin; oral
1.9
10.1
131
718
N03AX16
ATC
[U] pregabalin
1.5
10.1
395
2868
QAA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of head or neck
11.3
10.1
18
16
SPAT1325
SPAT
Vaccination
1.4
10.0
576
4485
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
2.5
10.0
59
236
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.7
10.0
171
1020
D05BB02
ATC
acitretin; oral
3.0
9.9
43
146
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
9.9
1283
11388
Z3231
NOMESCO Finland
Registered nurse
1.4
9.9
457
3424
XF404
NOMESCO Finland
Ambulatory ECG
1.8
9.8
153
887
Z2446
NOMESCO Finland
Social worker
1.9
9.8
115
610
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
9.8
804
6637
C44.81
ICD-10 Finland
Overall basocellular carcinoma of the skin
9.6
9.8
19
20
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
4.1
9.7
26
64
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.7
9.7
190
1177
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.5
9.7
305
2116
D07AA02
ATC
hydrocortisone; topical
1.6
9.6
234
1529
R06AE07
ATC
cetirizine; oral
1.4
9.6
770
6328
SPAT1260
SPAT
Consultation of another employee
1.5
9.5
298
2064
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
1.7
9.5
189
1175
C02AC05
ATC
moxonidine; oral
2.1
9.5
87
422
ZXA05
NOMESCO Finland
Left side
1.4
9.4
411
3040
SFA10
NOMESCO Finland
One-surface restoration
1.4
9.3
960
8181
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
4.4
9.3
23
53
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
2.4
9.3
62
263
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
9.3
849
7108
H13
ICPC
Plugged feeling ear
1.5
9.2
346
2486
137
Kela drug reimbursment
Uraemia requiring dialysis
7.3
9.2
21
29
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
3.3
9.2
34
105
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.0
9.1
100
518
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.2
9.1
78
368
D06BX01
ATC
metronidazole; topical
1.6
9.1
194
1227
L04AD02
ATC
tacrolimus; systemic
4.6
9.1
21
46
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
3.4
9.1
31
91
R03AC02
ATC
salbutamol; inhalant
1.3
9.1
973
8332
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.6
9.0
230
1522
Z01.2
ICD-10 Finland
Dental examination
1.3
9.0
813
6784
L01BA01
ATC
methotrexate; systemic
2.3
8.9
68
306
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
8.9
195
1243
R20.2
ICD-10 Finland
Paraesthesia of skin
1.8
8.8
124
698
ZXA00
NOMESCO Finland
Right side
1.4
8.8
442
3354
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
7.2
8.7
20
28
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
8.7
373
2746
D23.7
ICD-10 Finland
Benign neoplasm: Skin of lower limb, including hip
3.9
8.7
25
65
L80
ICD-10 Finland
Vitiligo
14.1
8.7
14
10
KMAK, ,
NOMESCO Finland
1.3
8.6
852
7191
P01AB01
ATC
metronidazole; oral, rectal
1.3
8.5
691
5659
QCA50
NOMESCO Finland
Cryotherapy of skin of upper limb
90.5
8.4
9
*
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.4
8.4
616
4965
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
4.9
8.4
18
37
SCA01
NOMESCO Finland
Preventive oral health care, short
1.4
8.4
487
3783
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
8.4
729
6030
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
2.3
8.3
64
289
L81.5
ICD-10 Finland
Leukoderma, not elsewhere classified
+∞
8.3
8
*
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.7
8.3
142
846
B05DB
ATC
Hypertonic solutions
8.6
8.3
17
20
E000007, ,
ATC
2.0
8.3
92
479
L29.0
ICD-10 Finland
Pruritus ani
3.8
8.2
24
63
N06AX11
ATC
mirtazapine; oral
1.4
8.2
594
4771
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
6.5
8.2
20
31
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.3
8.2
873
7427
L71.8
ICD-10 Finland
Other rosacea
3.0
8.2
34
113
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.6
8.1
177
1125
J01AA04
ATC
lymecycline; systemic
1.6
8.1
207
1367
D10AF01
ATC
clindamycin; topical
2.1
8.1
76
372
SDA03
NOMESCO Finland
Periodontal treatment
1.3
8.1
697
5745
ZZA00
NOMESCO Finland
Split skin graft
2.6
8.1
45
175
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.4
8.1
56
242
R01AD58
ATC
fluticasone, combinations; nasal
1.4
8.1
416
3162
L85.81
ICD-10 Finland
Keratosis pilaris
33.5
8.1
10
*
C43.31
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face originating in lentigo maligna
17.2
8.1
12
7
N05CF02
ATC
zolpidem; oral
1.5
8.1
298
2131
A08
ICPC
Swelling
1.9
8.0
106
585
J04BA02
ATC
dapsone; oral
10.1
8.0
15
15
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
1.8
8.0
123
711
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.4
8.0
483
3769
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
3.9
8.0
23
60
UKC02
NOMESCO Finland
Cystoscopy
1.5
8.0
242
1662
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
3.5
8.0
27
79
ZXC10
NOMESCO Finland
Use of laser
2.7
7.9
41
154
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.9
7.9
90
473
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
7.9
806
6802
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
2.7
7.9
42
160
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
7.9
306
2210
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.4
7.8
482
3772
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
7.8
941
8122
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
2.3
7.8
58
259
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
7.8
299
2154
ZX120
NOMESCO Finland
Intravenous
1.7
7.8
156
972
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
3.1
7.7
32
106
L04AX03
ATC
methotrexate; systemic
1.6
7.7
163
1028
R23.3
ICD-10 Finland
Spontaneous ecchymoses
2.6
7.7
42
162
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.8
7.7
114
652
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.6
7.7
196
1294
L70.0
ICD-10 Finland
Acne vulgaris
2.7
7.7
39
145
B05DA
ATC
Isotonic solutions
7.4
7.7
17
23
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
2.4
7.7
52
223
L71.9
ICD-10 Finland
Rosacea, unspecified
2.4
7.7
52
223
M79.7
ICD-10 Finland
Fibromyalgia
2.1
7.6
67
320
A11CC03
ATC
alfacalcidol; systemic
2.6
7.6
41
157
-, ,
ICD-10 Finland
2.6
7.6
42
163
XX9XE
NOMESCO Finland
Other ultrasound examination
4.0
7.6
21
53
H29
ICPC
Ear symptom/complaint other
1.5
7.6
216
1462
N02BE01
ATC
paracetamol; systemic, rectal
1.5
7.6
1639
15396
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.7
7.6
132
792
D07XC01
ATC
betamethasone; topical
1.6
7.5
186
1219
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.4
7.5
301
2186
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
7.5
216
1467
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
1.9
7.5
87
461
R50.9
ICD-10 Finland
Fever, unspecified
1.5
7.5
253
1777
Z2221
NOMESCO Finland
Medical doctor
1.4
7.5
446
3470
C08CA05
ATC
nifedipine; systemic
1.9
7.5
96
526
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
1.7
7.5
133
803
B35.3
ICD-10 Finland
Tinea pedis
2.1
7.5
72
357
L73.8
ICD-10 Finland
Other specified follicular disorders
3.9
7.4
21
54
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.7
7.4
142
874
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.8
7.4
116
675
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
7.4
167
1072
Q85.00
ICD-10 Finland
Neurofibromatosis, type 1
13.4
7.4
12
9
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
3.8
7.4
22
59
A11
ICPC
Chest pain NOS
1.6
7.4
155
978
M03BX02
ATC
tizanidine; oral
1.3
7.3
1059
9334
D01
ICPC
Abdominal pain/cramps general
1.5
7.3
219
1499
ZXA10
NOMESCO Finland
Bilateral
1.4
7.3
309
2265
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
7.3
313
2300
SFA20
NOMESCO Finland
Two-surface restoration
1.3
7.3
999
8741
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.6
7.3
152
956
7090A
ICD-9 Finland
Other disorders of skin and subcutaneous tissue, Dyschromia[CHLOASMA]
+∞
7.3
7
*
D11
ICPC
Diarrhoea
1.5
7.3
203
1368
Z71.8
ICD-10 Finland
Other specified counselling
1.3
7.3
584
4749
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.1
7.3
65
313
K07.63
ICD-10 Finland
Pain in the jaw joint UNS
2.5
7.3
42
167
NHQ40
NOMESCO Finland
Amputation of toe
4.2
7.3
19
46
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
3.5
7.3
24
69
K02.1
ICD-10 Finland
Caries of dentine
1.3
7.3
1002
8774
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
7.3
259
1838
C44.21
ICD-10 Finland
Basocellular carcinoma of the skin of the outer ear and the outer ear canal
3.8
7.3
21
55
SPAT1310
SPAT
Counselling related to known health issue
1.3
7.2
523
4189
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
2.2
7.2
61
288
N06AX21
ATC
duloxetine; oral
1.5
7.2
207
1406
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
3.6
7.1
23
65
K07.60
ICD-10 Finland
Snapping jaw
1.9
7.1
93
513
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.5
7.1
199
1344
CJB10
NOMESCO Finland
Laser discission of secondary cataract
1.6
7.1
151
956
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.6
7.1
168
1092
TQW40, ,
SPAT
1.6
7.1
179
1181
R21
ICPC
Throat symptom/complaint
1.4
7.1
335
2506
VALMI, ,
NOMESCO Finland
1.4
7.0
392
3012
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.7
7.0
135
832
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
7.0
412
3193
A02BC01
ATC
omeprazole; systemic
1.4
7.0
445
3493
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
7.0
650
5394
A02BC04
ATC
rabeprazole; oral
1.6
7.0
152
968
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.4
7.0
390
3000
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.6
6.9
173
1137
M01AH05
ATC
etoricoxib; oral
1.3
6.9
1068
9463
TK800
NOMESCO Finland
Hemodialysis
2.9
6.9
31
108
J05AB01
ATC
aciclovir; systemic
1.4
6.8
374
2864
H02AB04
ATC
methylprednisolone; systemic
1.5
6.8
231
1621
C10AA07
ATC
rosuvastatin; oral
1.3
6.8
572
4672
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
6.8
171
1125
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.2
6.8
56
261
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
8.3
6.8
14
17
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
6.7
6.8
16
24
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
6.8
408
3171
R01AD59
ATC
mometasone, combinations; nasal
1.8
6.8
107
624
D22
ICD-10 Finland
Melanocytic naevi
1.9
6.8
85
462
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
2.5
6.8
40
161
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
2.1
6.8
65
322
R31
ICD-10 Finland
Unspecified haematuria
1.6
6.8
149
951
7151
FHL
Kidney transplantation
40.2
6.8
8
*
8742/3-C44.9
ICD-O-3
Lentigo maligna melanoma of skin, NOS
40.2
6.8
8
*
K29.0
ICD-10 Finland
Acute haemorrhagic gastritis
5.7
6.8
18
32
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
3.5
6.7
22
63
E000003, ,
ATC
2.0
6.7
71
365
EMAK, ,
NOMESCO Finland
2.1
6.7
64
317
SAA04
NOMESCO Finland
Special examination of mouth
1.8
6.7
91
509
Z31.5
ICD-10 Finland
Genetic counselling
1.8
6.6
90
502
R03DC03
ATC
montelukast; oral
1.4
6.6
277
2025
A04
ICPC
Weakness/tiredness general
1.4
6.6
271
1974
J01CA04
ATC
amoxicillin; systemic
1.3
6.6
1453
13458
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.8
6.6
97
556
B35.1
ICD-10 Finland
Tinea unguium
1.7
6.5
112
670
K05.18
ICD-10 Finland
Chronic gingivitis
1.7
6.5
123
755
L15
ICPC
Knee symptom/complaint
1.3
6.5
450
3572
C44.52
ICD-10 Finland
Spinocellular carcinoma of the skin on the torso
6.2
6.5
16
26
L89
ICD-10 Finland
Decubitus ulcer and pressure area
6.2
6.5
16
26
D03.5
ICD-10 Finland
Melanoma in situ of trunk
5.7
6.4
17
30
M48.0
ICD-10 Finland
Spinal stenosis
1.5
6.4
210
1464
J01FA10
ATC
azithromycin; systemic
1.3
6.4
965
8489
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.5
6.4
241
1727
L50.9
ICD-10 Finland
Urticaria, unspecified
2.0
6.4
67
343
RJ210, ,
NOMESCO Finland
14.4
6.4
10
7
R01AD12
ATC
fluticasone furoate; nasal
1.3
6.4
511
4141
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.2
6.4
54
255
S06
ICPC
Rash localized
1.8
6.4
96
553
UDC00
NOMESCO Finland
Ear microscopy
1.7
6.4
122
752
D82
ICPC
Teeth/gum disease
1.3
6.4
612
5086
TPH07
NOMESCO Finland
Cathetrisation of artery
1.5
6.3
184
1251
J01EA01
ATC
trimethoprim; systemic
1.3
6.3
442
3512
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
6.3
136
863
A03FA02
ATC
cisapride; oral, rectal
1.7
6.3
123
761
G04CA02
ATC
tamsulosin; oral
1.4
6.3
297
2216
A02BA04
ATC
nizatidine; systemic
1.7
6.3
121
746
L12
ICPC
Hand/finger symptom/complaint
1.4
6.3
292
2173
J01MA14
ATC
moxifloxacin; systemic
1.6
6.3
141
904
D03.6
ICD-10 Finland
Melanoma in situ of upper limb, including shoulder
11.1
6.3
11
10
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
2.1
6.3
60
297
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.5
6.3
193
1329
QBA50
NOMESCO Finland
Cryotherapy of skin of trunk
18.1
6.3
9
5
70901
ICD-8 Finland
Other diseases of skin, Chloasma symptomaticum aliud sive NUD
+∞
6.3
6
*
L95.0
ICD-10 Finland
Livedoid vasculitis
+∞
6.3
6
*
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.7
6.2
102
602
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
3.0
6.2
26
87
C44.90
ICD-10 Finland
Unspecified localization of malignant tumor of the skin without histology
26.8
6.2
8
*
L04AA13
ATC
[U] leflunomide
2.3
6.2
44
193
R01AD09
ATC
mometasone; nasal
1.3
6.2
754
6451
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.0
6.2
66
340
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.6
6.2
130
820
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
6.2
611
5091
WX704
NOMESCO Finland
Intubation
1.6
6.2
136
868
V03AE01
ATC
polystyrene sulfonate; oral
3.5
6.2
20
57
A07AA02
ATC
nystatin; oral
1.7
6.1
97
567
H02.3
ICD-10 Finland
Blepharochalasis
1.7
6.1
114
697
A01
ICPC
Pain general/multiple sites
1.5
6.1
179
1219
J01DA01
ATC
[U] cefalexin
1.3
6.1
1040
9263
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
6.1
875
7633
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
2.1
6.1
56
273
AA1AD
NOMESCO Finland
CT of head and brain
1.3
6.1
489
3959
A05
ICPC
Feeling ill
1.7
6.1
104
621
S19
ICPC
Skin injury other
2.0
6.1
65
335
S01
ICPC
Pain/tenderness of skin
1.8
6.1
80
442
L03
ICPC
Low back symptom/complaint
1.3
6.1
504
4100
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.4
6.1
291
2177
W00
ICD-10 Finland
Fall on same level involving ice and snow
1.5
6.1
185
1271
R39.1
ICD-10 Finland
Other difficulties with micturition
2.1
6.1
53
254
H02
ICPC
Hearing complaint
1.4
6.1
257
1883
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
1.7
6.0
118
731
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.5
6.0
179
1223
K07
ICPC
Swollen ankles/oedema
1.8
6.0
83
466
L29.9
ICD-10 Finland
Pruritus, unspecified
2.1
6.0
52
248
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.1
6.0
52
248
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.6
6.0
137
882
J01AA02
ATC
doxycycline; systemic
1.3
6.0
1364
12579
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1198
8965
1.91
38.89
8.7
6.2
0.20
0.19
e9/l
1.20
1094
7752
1183
8831
1.90
38.52
8.5
6.1
1.85
1.94
e9/l
1.67
1089
7710
1544
13024
1.99
29.75
10.2
8.1
77.75
79.46
u/l
0.96
1474
12334
1242
9814
1.77
29.36
12.0
9.5
3.93
4.08
e9/l
1.09
1114
8500
138
495
2.93
28.52
1.5
1.6
1.16
1.20
g/l
0.75
130
467
162
634
2.70
28.42
1.3
1.2
0.41
1.03
u/ml
0.79
16
48
1494
12547
1.89
28.01
5.9
4.3
11.84
12.36
mm/h
0.73
1411
11717
1169
9183
1.71
27.15
5.3
4.0
0.00
0.18
estimate
0.52
223
1798
1151
9004
1.71
27.15
5.2
4.0
0.00
0.00
estimate
0.80
236
1847
1162
9117
1.71
27.07
5.2
4.0
6.31
3.35
estimate
0.19
239
1902
1046
8004
1.68
26.55
2.9
2.5
79.78
78.12
nmol/l
1.11
961
7235
1012
7742
1.66
25.15
6.0
4.8
36.30
35.68
g/l
3.22
959
7246
124
480
2.69
22.17
1.6
1.6
0.23
0.24
g/l
0.12
112
454
1560
13604
1.82
21.76
25.9
19.5
13.69
13.64
%
0.78
1545
13422
1135
9144
1.60
21.22
7.2
6.6
10.98
11.65
umol/l
1.73
1085
8716
1099
8804
1.59
20.90
8.7
7.0
1.22
1.22
mmol/l
0.61
964
7592
1775
16255
2.40
20.54
20.8
15.5
22.30
23.92
mg/l
1.32
1502
13403
1007
7929
1.57
20.44
7.3
6.4
1.22
1.21
mmol/l
0.89
944
7305
886
6813
1.56
19.68
5.0
3.9
0.02
0.14
estimate
1.08
192
1529
1325
11230
1.59
18.64
5.9
4.8
1223.47
1900.10
e6/l
0.23
27
172
150
690
2.27
18.49
1.5
1.4
6.07
11.19
iu/ml
—
6
16
148
678
2.28
18.42
1.8
1.7
12.53
7.86
iu/ml
0.49
32
149
1828
17111
2.80
17.59
15.7
12.1
24.77
25.20
u/l
0.55
1786
16629
976
7797
1.52
17.39
16.2
14.8
1.25
1.25
inr
0.05
823
6456
1496
13139
1.65
17.36
5.3
4.6
14.83
14.82
pmol/l
0.09
1387
12056
1795
16680
2.38
17.24
23.9
18.7
3.98
3.97
mmol/l
0.91
1765
16340
1791
16655
2.31
16.69
23.6
18.5
139.67
139.68
mmol/l
0.09
1764
16349
1686
15356
1.87
16.53
6.6
5.6
1.94
1.93
mu/l
0.14
1589
14191
359
2300
1.69
16.47
7.2
5.1
1.05
1.04
mmol/l
0.30
333
2115
942
7543
1.49
16.11
14.4
11.1
0.00
0.00
e9/l
0.96
797
6115
561
4052
1.55
15.58
5.2
4.1
1.02
1.02
kg/l
1.90
385
2676
716
5455
1.50
15.44
3.1
2.6
59.55
60.98
u/l
0.27
660
5047
793
6182
1.49
15.20
3.8
3.5
2.35
2.36
mmol/l
0.82
733
5630
237
1392
1.80
14.68
3.4
2.4
0.25
0.50
e6/l
1.58
227
1322
982
8026
1.46
14.55
3.6
3.0
113.23
116.81
ug/l
0.25
920
7474
1856
17664
3.19
14.36
32.0
24.0
247.80
252.85
e9/l
2.82
1835
17314
1856
17665
3.19
14.34
31.8
23.9
91.29
91.15
fl
0.66
1847
17486
1856
17668
3.18
14.27
31.9
24.0
4.44
4.45
e12/l
0.59
1834
17267
1856
17668
3.18
14.27
32.3
24.4
40.05
40.05
%
0.01
1847
17481
1856
17670
3.17
14.23
32.0
24.0
6.60
6.69
e9/l
1.02
1832
17263
690
5284
1.48
14.20
2.4
2.1
149.09
219.42
u/l
2.30
655
5014
1856
17674
3.16
14.15
32.1
24.1
133.97
133.98
g/l
0.01
1848
17498
242
1447
1.77
14.09
2.9
2.8
66.86
66.59
g/l
0.21
225
1325
532
3871
1.52
14.01
3.9
2.5
5.11
6.29
e6/l
1.31
498
3514
1824
17251
2.43
13.60
27.2
20.5
80.22
75.27
umol/l
5.03
1807
17062
658
5028
1.47
13.53
5.5
4.1
0.00
0.01
estimate
1.54
223
1728
457
3244
1.54
13.42
1.5
1.3
32.26
34.17
iu/ml
0.09
141
1019
545
4026
1.50
13.22
1.4
1.3
1.50
1.60
u/ml
0.06
158
1062
1173
10028
1.44
13.00
5.5
5.0
6.44
6.63
mmol/l
3.11
1129
9478
462
3308
1.52
12.97
4.7
3.8
212.13
398.23
ng/l
1.48
367
2597
200
1161
1.81
12.83
1.4
1.3
182.47
198.83
u/ml
0.13
188
1067
718
5640
1.44
12.53
4.8
3.2
19.57
86.71
e6/l
3.53
580
4267
231
1408
1.73
12.52
4.0
3.7
95.24
83.86
ng/l
0.93
211
1215
216
1292
1.76
12.51
3.4
2.8
10.45
10.68
g/l
0.31
204
1191
802
6429
1.43
12.51
5.8
3.9
50.24
108.91
e6/l
2.91
604
4462
105
492
2.20
12.40
1.3
1.2
23.92
33.84
u/ml
—
5
27
565
4265
1.46
12.09
3.8
2.6
333.48
336.90
umol/l
0.35
502
3734
628
4854
1.44
11.79
4.4
3.1
0.31
0.44
e6/l
1.12
486
3523
313
2103
1.58
11.56
2.1
1.8
—
—
—
0
0
1737
16263
1.79
11.50
6.7
5.8
2.65
2.71
mmol/l
2.13
1628
15066
1659
15346
1.64
11.46
7.1
6.3
38.73
39.16
mmol/mol
1.52
1576
14331
210
1280
1.72
11.36
1.7
1.5
—
—
—
0
0
99
470
2.17
11.33
1.4
1.2
1.97
2.34
u/ml
—
10
47
1491
13497
1.49
11.09
28.0
20.5
332.04
331.80
g/l
0.47
1486
13427
75
320
2.40
11.04
9.3
4.8
112.13
509.39
iu/ml
2.20
15
38
1152
9959
1.40
11.04
3.2
3.0
—
—
—
0
0
98
472
2.13
10.83
1.3
1.3
8.28
8.01
u/ml
0.02
15
79
378
2684
1.51
10.82
3.0
2.4
2.37
2.34
g/l
0.51
346
2467
323
2224
1.54
10.65
2.1
1.8
—
—
—
0
0
402
2900
1.49
10.63
3.1
2.5
13.05
13.00
umol/l
0.04
375
2695
470
3498
1.46
10.60
1.7
1.5
2.36
2.39
g/l
0.11
311
2107
496
3730
1.45
10.59
1.8
1.8
1.20
1.34
mg/l
0.35
381
2891
618
4841
1.41
10.50
4.1
3.4
0.01
0.22
estimate
0.66
194
1462
1711
16029
1.68
10.29
5.9
5.1
4.58
4.66
mmol/l
2.71
1615
14917
316
2185
1.54
10.19
2.7
2.4
92.07
119.24
ug/g
1.98
248
1728
853
7081
1.37
10.11
2.0
1.9
1.27
1.34
mmol/l
2.47
711
5966
287
1951
1.55
9.99
4.6
4.3
232.86
247.83
u/l
1.33
279
1840
390
2832
1.47
9.91
1.6
1.5
—
—
—
0
0
127
694
1.89
9.88
2.0
2.0
39.82
39.13
u/l
0.14
116
612
1700
15928
1.64
9.87
5.7
5.0
1.51
1.50
mmol/l
0.64
1588
14722
1680
15703
1.60
9.76
6.0
5.2
5.83
5.91
mmol/l
2.09
1561
14388
707
5731
1.37
9.58
4.1
3.3
31.11
33.27
u/l
0.79
669
5418
211
1349
1.63
9.49
3.4
3.0
153.41
196.56
ng/l
1.58
195
1237
79
369
2.19
9.46
1.2
1.2
39.96
47.13
u/ml
—
7
39
399
2938
1.45
9.38
2.1
1.8
—
—
—
0
0
168
1021
1.71
9.17
2.4
1.8
1.78
1.43
g/l
0.38
156
944
470
3580
1.42
9.16
2.9
3.0
2.45
2.46
mmol/l
0.21
426
3237
342
2465
1.47
8.95
3.2
2.5
22.58
22.50
%
0.04
317
2289
241
1623
1.56
8.70
2.8
2.2
365.41
379.05
nmol/l
0.45
227
1505
53
216
2.50
8.67
1.5
1.4
—
—
—
0
0
390
2899
1.43
8.65
4.1
3.3
0.81
0.82
mmol/l
0.51
367
2743
631
5090
1.36
8.59
1.8
1.7
22.68
20.53
nmol/l
1.78
547
4267
352
2583
1.45
8.35
2.1
2.1
29.98
29.48
s
0.84
340
2506
281
1979
1.49
8.22
3.0
2.8
6.75
7.53
umol/l
0.51
248
1745
719
5963
1.33
8.00
3.7
3.3
6.76
7.25
mmol/l
2.66
617
5023
37
133
2.82
7.76
1.2
1.1
110.00
160.45
titre
—
7
22
63
292
2.20
7.74
1.6
1.5
185.00
153.70
au/ml
1.29
18
91
896
7701
1.31
7.60
2.4
2.1
99.30
95.58
pmol/l
1.57
456
3949
769
6479
1.31
7.52
3.9
3.8
37.67
75.98
ng/l
1.24
530
4596
397
3030
1.39
7.47
1.5
1.3
9.64
13.30
u/ml
0.55
168
1140
397
3035
1.39
7.39
3.9
2.8
0.95
1.20
e6/l
0.63
233
1574
89
482
1.89
7.18
2.3
2.5
3.43
3.59
g/l
0.47
82
461
220
1525
1.50
6.92
2.5
2.5
73.58
70.05
e9/l
0.63
152
1121
217
1502
1.50
6.88
10.9
6.7
10.60
9.43
mmol/l
1.63
211
1433
102
588
1.78
6.75
2.7
2.7
—
—
—
0
0
682
5719
1.30
6.70
4.5
4.0
8.43
10.91
mg/mmol
0.30
391
3441
236
1686
1.46
6.38
3.1
2.3
35.14
39.59
u/l
0.59
197
1413
158
1039
1.57
6.33
1.3
1.3
36.98
51.47
au/ml
—
8
78
1611
15195
1.40
6.27
4.9
4.3
1.22
1.27
mmol/l
2.53
1488
13907
84
468
1.83
6.24
2.3
2.5
184.42
191.07
%
0.25
74
446
1652
15653
1.42
6.23
20.5
15.3
78.17
80.13
ml/min/173m2
3.26
1555
14513
558
4592
1.30
6.21
2.7
2.3
2.69
2.83
mg/l
0.59
488
3937
63
320
2.00
6.17
1.5
1.3
297.98
234.84
u/ml
0.78
45
182
88
500
1.80
6.14
1.5
1.5
0.06
1.58
iu/ml
0.49
22
92
192
1329
1.49
6.09
3.2
2.8
60.11
66.64
ml/min/173m2
1.45
88
579
103
618
1.70
5.96
2.9
2.2
11.16
10.38
g/l
0.66
96
549
103
620
1.70
5.89
1.7
1.6
8.68
15.20
u/ml
1.75
24
130
169
1149
1.52
5.84
2.4
2.4
34.44
22.60
au/ml
0.55
12
110
33
131
2.55
5.79
1.2
1.2
—
—
—
0
0
179
1241
1.49
5.64
1.7
1.6
—
—
—
0
0
358
2801
1.34
5.63
4.0
2.9
2.85
2.80
e6/l
0.04
193
1338
33
133
2.51
5.63
1.2
1.2
—
—
—
0
0
33
133
2.51
5.63
1.2
1.2
—
—
—
0
0
114
714
1.63
5.62
3.0
2.2
3.75
3.78
g/l
0.06
108
651
114
715
1.63
5.59
3.0
2.2
7.05
7.44
g/l
1.67
108
651
114
715
1.63
5.59
3.0
2.2
4.16
4.22
g/l
0.36
108
652
622
5257
1.27
5.50
3.3
3.2
1507.80
1238.58
ng/l
0.34
528
4487
28
106
2.67
5.41
1.9
1.6
112.00
97.88
ng/l
0.39
28
106
85
499
1.74
5.34
2.1
2.3
91.43
91.99
%
0.08
78
482
66
360
1.86
5.29
1.8
1.4
—
—
—
0
0
1200
10968
1.26
5.28
3.6
3.3
43.93
47.10
u/l
0.72
1139
10284
36
156
2.33
5.27
1.2
1.2
—
—
—
0
0
16
44
3.66
5.20
2.2
3.9
233.60
36.91
au/ml
—
5
13
262
1978
1.38
5.17
6.2
7.8
1.16
0.94
mmol/l
0.54
211
1638
85
504
1.72
5.17
2.4
2.3
0.02
0.00
g/l
0.49
75
447
115
738
1.59
5.16
1.9
1.9
1.50
1.53
g/l
0.10
102
643
87
522
1.70
5.07
2.5
2.3
0.02
0.04
g/l
0.15
78
473
263
1994
1.37
5.05
6.1
7.9
5.06
5.09
kpa
0.26
249
1916
263
1995
1.37
5.04
6.1
7.9
11.91
12.33
kpa
0.71
247
1918
33
141
2.36
5.00
1.2
1.2
—
—
—
0
0
31
129
2.43
4.97
1.2
1.2
—
—
—
0
0
16
46
3.50
4.89
1.1
1.2
98.40
87.48
%
—
5
25
16
46
3.50
4.89
1.1
1.7
93.80
87.85
%
—
5
26
66
370
1.81
4.87
1.9
1.4
—
—
—
0
0
83
499
1.69
4.82
4.3
4.7
1.86
1.47
mg/l
2.26
70
447
105
671
1.60
4.81
3.0
2.3
2.81
2.96
g/l
0.91
99
608
79
470
1.71
4.77
2.5
2.3
0.00
0.00
g/l
-0.00
74
446
21
74
2.86
4.66
2.2
2.5
905.57
1050.26
u/ml
0.22
21
74
13
26
5.03
4.63
1.2
1.3
—
82.86
—
0
7
169
1208
1.44
4.58
1.2
1.2
133.82
136.34
u/ml
0.03
62
465
364
2935
1.30
4.57
1.7
1.6
—
—
—
0
0
68
393
1.76
4.56
1.3
1.4
12.97
10.25
u/l
0.80
53
310
(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay
13
27
4.84
4.49
1.2
1.3
—
68.57
—
0
7
358
2890
1.29
4.45
1.8
1.7
1181.78
1187.44
nmol/l
0.04
282
2180
11
19
5.82
4.44
3.6
1.4
—
—
—
0
0
75
450
1.69
4.41
3.0
3.3
1.78
2.20
index
0.31
36
229
96
624
1.57
4.13
2.6
2.4
1.02
1.06
g/l
0.03
85
535
17
57
3.00
4.12
1.2
1.1
—
—
—
0
0
8
10
8.03
4.06
2.4
1.1
—
—
—
0
0
35
169
2.09
4.03
1.1
1.2
—
—
—
0
0
13
31
4.22
4.01
1.0
2.3
1.43
2.51
ug/l
—
6
16
9
14
6.45
3.98
1.3
1.9
—
—
—
0
0
48
261
1.86
3.96
1.6
1.6
—
—
—
0
0
14
43
3.27
3.91
2.4
2.2
0.62
0.62
mmol/l
0.02
14
43
84
538
1.59
3.87
3.8
3.3
1.50
3.96
ratio
1.57
41
312
80
507
1.60
3.85
2.2
2.1
2776.90
5029.80
u/l
0.48
25
224
54
308
1.78
3.84
1.9
1.4
—
—
—
0
0
884
7981
1.20
3.80
2.9
2.8
—
—
estimate
—
0
0
56
325
1.75
3.76
1.3
1.3
—
—
—
0
0
56
325
1.75
3.76
1.3
1.3
—
—
—
0
0
70
432
1.64
3.75
1.8
1.5
—
—
—
0
0
80
512
1.59
3.71
1.4
1.3
299.27
238.04
miu/ml
0.61
35
228
87
569
1.55
3.68
2.1
1.6
—
—
—
0
0
21
85
2.49
3.63
1.3
1.2
—
—
—
0
0
77
492
1.59
3.60
1.5
1.3
—
—
—
0
0
40
212
1.91
3.59
2.1
1.5
—
—
—
0
0
10
21
4.78
3.55
1.2
1.4
—
—
—
0
0
435
3688
1.23
3.51
1.8
1.7
134722664.95
30344139.57
pmol/l
1.04
360
3055
50
288
1.76
3.47
2.0
1.5
—
—
—
0
0
89
594
1.52
3.45
4.0
3.5
48.34
152.65
mg/l
0.62
75
520
89
594
1.52
3.45
4.0
3.6
37.08
71.15
mg/l
0.93
75
520
462
3948
1.22
3.45
6.1
5.6
2.27
2.68
ug/l
0.62
416
3543
132
953
1.41
3.44
2.5
2.0
—
—
—
0
0
69
435
1.61
3.43
1.8
1.6
—
—
—
0
0
81
531
1.55
3.41
1.6
1.4
275.30
279.79
ug/g
0.07
49
312
53
314
1.71
3.34
1.4
1.4
—
—
—
0
0
41
225
1.84
3.34
1.2
1.3
326.29
322.96
pmol/l
0.03
35
193
225
1775
1.30
3.32
6.2
8.3
96.29
95.45
%
2.25
220
1718
42
233
1.82
3.31
1.3
1.2
1.73
4.90
u/ml
1.38
11
80
214
1679
1.31
3.29
2.4
2.3
0.20
0.21
g/l
1.43
199
1580
43
242
1.79
3.24
1.4
1.4
0.60
7.97
nmol/l
0.50
43
233
44
250
1.78
3.21
1.4
1.4
—
—
—
0
0
159
2079
0.74
3.20
5.6
5.0
32.88
32.96
%
0.03
120
1341
140
1037
1.38
3.16
2.5
2.3
13.53
12.61
nmol/l
0.57
124
922
182
1406
1.33
3.13
4.4
3.4
1.23
1.23
mmol/l
0.35
156
1198
109
783
1.42
2.96
2.4
1.9
—
—
—
0
0
28
141
2.00
2.95
1.8
1.2
0.28
1.57
u/ml
1.04
19
76
67
437
1.55
2.93
1.8
1.7
7437.60
12573.19
e6/l
1.04
47
303
241
1956
1.27
2.86
9.2
6.6
—
—
—
0
0
34
186
1.84
2.84
5.2
4.9
6.45
7.15
mmol/l
1.10
29
154
22
103
2.15
2.81
3.1
2.1
—
—
—
0
0
213
1710
1.28
2.77
3.9
3.3
—
—
—
0
0
65
428
1.54
2.74
1.1
1.1
3.39
5.96
eliau/ml
—
8
49
213
1714
1.27
2.72
4.0
3.6
1.60
1.82
mmol/l
0.40
193
1472
6
10
6.02
2.70
1.2
1.1
—
—
—
0
0
37
212
1.76
2.68
1.3
1.4
0.16
0.27
nmol/l
0.71
31
168
496
4361
1.19
2.67
5.3
3.9
88.38
90.43
%
1.05
481
4266
67
447
1.52
2.67
2.0
1.5
—
—
—
0
0
368
3155
1.21
2.62
5.4
4.5
23.23
21.27
%
1.70
173
1551
5
7
7.16
2.55
6.0
5.6
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
73
502
1.47
2.53
4.5
3.2
0.32
0.39
iu/ml
0.82
39
265
77
537
1.45
2.49
1.6
1.5
—
—
—
0
0
46
287
1.62
2.46
1.3
1.3
—
—
—
0
0
27
144
1.89
2.46
1.1
1.0
—
—
—
0
0
14
57
2.47
2.45
1.0
1.0
—
—
—
0
0
70
482
1.47
2.43
1.4
1.3
—
—
—
0
0
18
83
2.18
2.41
1.1
1.2
0.60
0.52
ratio
—
10
54
24
124
1.95
2.40
1.7
1.5
14.29
19.22
u/ml
—
7
18
6
12
5.01
2.40
5.2
3.9
24.83
28.33
mg/l
—
6
12
32
182
1.77
2.40
4.0
3.4
—
—
—
0
0
37
220
1.70
2.38
2.1
1.5
—
—
—
0
0
69
476
1.47
2.38
1.3
1.3
—
—
—
0
0
116
879
1.34
2.33
1.6
1.5
—
—
—
0
0
14
59
2.38
2.29
3.1
1.2
—
—
—
0
0
37
226
1.65
2.18
1.1
1.1
—
—
—
0
0
133
1043
1.30
2.12
3.5
3.7
23.93
24.18
mmol/l
0.48
133
1032
139
1099
1.29
2.09
2.0
1.6
—
—
—
0
0
11
43
2.57
2.08
1.0
1.1
—
—
—
0
0
117
908
1.31
2.03
4.1
3.4
1.02
1.02
ratio
0.91
104
829
78
569
1.39
2.02
3.5
3.1
24.70
24.88
mmol/l
0.20
78
560
18
90
2.01
2.00
1.2
1.0
1849.33
1566.70
miu/ml
0.54
18
90
37
232
1.61
1.99
1.2
1.2
2.38
4.97
u/ml
1.32
13
96
65
462
1.42
1.96
1.2
1.2
—
—
—
0
0
43
282
1.54
1.93
1.1
1.3
47.70
31.95
u/l
0.37
36
241
32
196
1.64
1.90
1.5
1.4
279.84
278.32
mosm/kgh2o
0.12
25
153
70
508
1.39
1.89
1.3
1.3
—
—
—
0
0
25
143
1.76
1.89
2.0
1.5
3.47
4.28
mg/l
0.35
25
136
25
144
1.75
1.85
2.8
1.5
—
—
—
0
0
104
809
1.30
1.80
1.5
1.4
—
—
—
0
0
17
87
1.96
1.80
1.9
1.9
—
—
—
0
0
17
87
1.96
1.80
1.9
1.9
—
—
—
0
0
64
462
1.40
1.80
1.2
1.1
—
—
—
0
0
17
90
1.90
1.65
1.2
1.5
—
—
—
0
0
33
213
1.56
1.62
1.1
1.2
116.33
115.05
%
0.08
27
189
164
1369
1.22
1.59
2.0
2.3
6.99
7.27
ug/l
0.07
149
1212
80
613
1.32
1.58
1.6
1.4
—
—
—
0
0
111
891
1.26
1.54
1.1
1.0
—
—
—
0
0
50
357
1.41
1.53
1.3
1.1
4.03
2.49
u/ml
0.23
34
200
49
349
1.41
1.52
1.8
1.6
—
—
—
0
0
62
460
1.36
1.52
1.5
1.4
—
—
—
0
0
34
225
1.52
1.52
1.4
1.3
30.35
28.72
u/l
0.09
28
186
6
21
2.86
1.50
1.0
1.0
12.67
14.67
pmol/l
—
6
21
24
381
0.63
1.50
1.4
1.6
62.72
60.73
ug/l
0.06
17
326
16
86
1.87
1.50
1.3
1.4
—
—
—
0
0
15
79
1.91
1.49
3.5
3.5
0.93
1.33
%
0.57
15
79
17
94
1.82
1.47
1.1
1.1
95.39
82.56
u/l
0.21
17
85
50
360
1.40
1.47
2.9
3.4
17.38
25.38
mg/l
1.49
32
251
16
87
1.85
1.46
1.1
1.1
1.09
1.20
u/l
—
10
46
24
148
1.63
1.44
1.4
1.2
—
—
—
0
0
17
95
1.80
1.43
2.9
1.9
369.60
494.55
e6/l
—
10
73
16
88
1.83
1.41
1.3
1.4
—
—
—
0
0
11
53
2.08
1.38
1.5
1.5
87.64
595.74
nmol/24h
0.48
11
53
20
119
1.69
1.37
1.0
1.1
11.86
9.30
iu/ml
—
5
30
114
933
1.24
1.36
3.1
3.0
1.11
1.16
%
0.30
114
926
22
136
1.62
1.32
2.1
1.6
41.72
33.17
%
0.50
13
88
51
378
1.36
1.29
1.1
1.3
8.28
55.64
e6/l
1.36
36
283
134
1124
1.21
1.28
3.3
3.4
4.53
4.49
pmol/l
0.16
110
1003
8
35
2.29
1.27
1.0
1.1
—
—
—
0
0
51
381
1.35
1.24
1.2
1.4
360.17
1092.85
e6/l
0.91
41
297
8
36
2.23
1.24
1.0
1.2
—
—
—
0
0
94
763
1.24
1.23
1.4
1.4
32.50
29.03
iu/l
0.41
83
649
67
522
1.29
1.22
1.5
1.6
266.05
302.48
mu/l
0.74
61
476
51
382
1.34
1.22
1.1
1.2
3.54
3.73
mmol/l
1.14
46
362
5
19
2.64
1.21
1.0
1.0
—
—
—
0
0
25
164
1.53
1.20
1.6
1.2
102.32
107.31
pmol/l
0.28
25
164
13
71
1.84
1.19
1.5
1.3
181.02
165.26
pmol/l
0.21
13
71
83
668
1.25
1.18
1.5
1.6
0.28
0.30
mg/l
0.14
35
300
182
1582
1.17
1.17
6.9
7.6
1.22
1.33
mmol/l
1.09
176
1551
0
35
0.00
1.15
0.0
2.3
—
7.08
—
0
21
13
72
1.81
1.15
1.1
1.2
—
69.00
%
—
0
12
20
126
1.59
1.14
1.4
1.5
—
—
—
0
0
27
183
1.48
1.13
1.4
1.6
9.98
4.15
ug/l
0.46
22
159
51
388
1.32
1.12
2.0
1.6
—
—
—
0
0
133
1132
1.19
1.11
3.8
4.1
5.11
5.13
kpa
0.12
126
1087
84
683
1.24
1.11
3.0
3.6
53.50
5995.13
u/ml
0.86
73
591
24
352
0.68
1.10
1.3
1.5
1.01
1.13
ratio
0.45
13
224
24
352
0.68
1.10
1.3
1.5
1.02
1.21
ratio
1.25
13
224
24
352
0.68
1.10
1.3
1.5
1.04
0.95
ratio
0.48
13
224
28
193
1.46
1.09
1.8
1.6
55.19
57.55
%
0.11
16
124
5
21
2.38
1.09
4.0
1.3
—
—
—
0
0
19
120
1.59
1.08
1.1
1.2
0.11
6.57
nmol/l
—
6
22
20
128
1.57
1.08
1.1
1.2
1.76
2.10
mmol/l
1.45
15
120
25
170
1.48
1.05
1.1
1.3
—
—
—
0
0
24
347
0.69
1.03
1.3
1.5
—
—
—
0
0
16
98
1.64
1.03
1.2
1.1
—
—
—
0
0
23
155
1.49
1.01
1.6
1.5
—
—
—
0
0
53
413
1.29
1.01
3.3
2.2
127.82
128.56
g/l
0.09
45
332
25
172
1.46
1.00
3.9
3.1
14.00
12.33
index
0.55
14
95
17
107
1.59
0.99
1.8
1.4
—
75.00
—
0
12
11
61
1.81
0.98
1.1
1.1
—
—
—
0
0
5
23
2.18
0.98
1.4
1.3
—
—
—
0
0
20
132
1.52
0.97
1.2
1.0
—
—
—
0
0
25
174
1.44
0.95
1.5
1.4
—
—
—
0
0
39
295
1.33
0.93
1.3
1.1
0.37
2.08
u/ml
1.74
19
129
11
184
0.60
0.92
1.0
1.2
—
—
—
0
0
26
184
1.42
0.91
1.5
1.4
54710.78
75263.58
e6/l
0.21
18
97
27
193
1.40
0.90
1.3
1.4
6.51
6.48
mmol/l
0.02
22
181
127
1100
1.17
0.90
8.2
9.8
0.64
0.64
%
0.02
127
1092
23
160
1.44
0.89
1.5
1.4
120158.60
148643.01
e6/l
0.09
15
107
48
377
1.28
0.88
2.2
1.8
47.13
41.58
nmol/l
0.60
48
359
56
449
1.25
0.88
3.6
4.1
3.85
3.86
mmol/l
0.05
56
443
16
103
1.56
0.87
1.4
1.3
—
—
—
0
0
8
43
1.86
0.87
1.9
1.3
8.32
8.92
ug/l
—
8
43
11
180
0.61
0.86
1.3
1.2
—
—
—
0
0
130
1135
1.16
0.84
8.0
9.7
94.44
93.93
%
0.86
130
1127
14
88
1.60
0.84
1.4
1.2
—
—
—
0
0
6
33
1.82
0.79
1.2
1.1
—
—
—
0
0
29
216
1.35
0.79
1.5
1.4
1510.71
1844.68
e6/l
0.19
21
142
34
260
1.31
0.78
1.1
1.1
111.60
104.92
iu/ml
—
10
55
119
1040
1.15
0.78
8.4
9.5
24.36
24.28
mmol/l
0.12
114
1021
44
349
1.27
0.77
3.3
3.5
0.74
0.82
nmol/l
0.89
37
296
17
115
1.48
0.77
2.1
1.8
—
—
—
0
0
100
864
1.17
0.76
5.0
3.9
47.87
47.43
%
0.06
100
847
28
210
1.34
0.74
1.1
1.6
58.30
54.41
ug/l
0.17
28
210
9
55
1.64
0.73
1.1
1.4
—
—
—
0
0
9
55
1.64
0.73
1.1
1.4
—
—
—
0
0
30
228
1.32
0.73
1.2
1.1
4.82
5.29
u/ml
0.04
15
99
166
1492
1.12
0.72
3.1
2.0
—
—
—
0
0
9
56
1.61
0.72
1.1
1.4
—
—
—
0
0
111
972
1.15
0.72
3.9
4.0
1.60
1.88
mmol/l
0.48
86
715
51
620
0.82
0.71
1.4
1.6
1232.27
989.50
mu/l
0.70
41
518
7
40
1.75
0.71
3.0
2.3
7.73
18.54
umol/l
—
7
40
7
40
1.75
0.71
1.3
1.2
—
—
—
0
0
70
591
1.19
0.71
1.8
1.7
3.06
4.93
mg/l
0.94
48
431
14
93
1.51
0.69
3.2
1.8
—
—
—
0
0
14
93
1.51
0.69
1.1
1.1
—
—
—
0
0
11
69
1.60
0.68
1.1
1.4
117.18
160.47
mmol/24h
1.58
11
69
17
119
1.43
0.67
1.2
1.3
—
—
—
0
0
7
43
1.63
0.67
1.3
1.0
—
—
—
0
0
7
44
1.59
0.65
1.0
1.1
—
—
—
0
0
25
189
1.33
0.64
2.0
1.5
—
—
—
0
0
14
95
1.48
0.64
3.0
2.0
298.56
216.87
e6/l
—
9
79
179
1636
1.10
0.60
3.1
2.1
—
—
—
0
0
12
80
1.50
0.59
1.4
2.1
2.28
1.99
umol/l
0.55
12
68
33
408
0.81
0.57
1.3
1.4
—
—
—
0
0
37
302
1.23
0.55
1.3
1.1
5.59
5.41
u/ml
0.03
21
165
10
65
1.54
0.55
1.3
1.2
—
—
—
0
0
9
60
1.50
0.54
2.1
2.2
17.00
149.56
ug/l
—
9
53
11
74
1.49
0.53
1.1
1.4
—
—
—
0
0
11
74
1.49
0.53
1.1
1.4
—
—
—
0
0
11
74
1.49
0.53
1.1
1.4
—
—
—
0
0
11
74
1.49
0.53
1.1
1.4
—
—
—
0
0
18
134
1.35
0.53
1.4
1.4
—
—
—
0
0
18
134
1.35
0.53
1.4
1.4
—
—
—
0
0
18
134
1.35
0.53
1.4
1.4
—
—
—
0
0
42
350
1.20
0.53
3.0
2.3
44.83
97.41
ug/min
1.04
29
212
10
66
1.52
0.52
1.0
1.2
—
—
—
0
0
31
250
1.24
0.52
1.2
1.0
1.28
3.82
u/ml
1.54
20
125
27
215
1.26
0.51
1.2
1.0
0.11
0.37
u/ml
—
10
76
10
67
1.50
0.49
2.7
2.4
56.54
47.24
umol/l
—
10
56
11
76
1.45
0.48
1.1
1.1
—
—
—
0
0
6
94
0.64
0.42
1.0
1.4
—
—
—
0
0
8
59
1.36
0.41
2.0
2.8
9.29
10.05
kpa
—
8
59
8
59
1.36
0.41
2.0
2.8
4.72
4.88
kpa
—
8
59
12
88
1.37
0.40
1.4
1.7
—
—
—
0
0
7
101
0.69
0.39
1.1
1.2
—
—
—
0
0
13
97
1.34
0.39
1.3
1.3
21.98
23.19
umol/l
0.05
13
86
0
19
0.00
0.39
0.0
1.3
—
6.06
—
0
19
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
58
514
1.13
0.38
2.6
2.0
135.72
14.41
iu/l
0.43
24
216
199
1876
1.07
0.37
4.1
4.4
5.50
20.24
ug/l
2.36
164
1533
9
70
1.29
0.36
1.1
1.4
—
—
—
0
0
246
2338
1.06
0.36
3.3
3.2
0.82
0.78
ug/l
0.27
158
1521
5
76
0.66
0.35
7.6
3.6
—
—
—
0
0
114
1054
1.09
0.35
3.6
3.7
22.78
73.44
u/ml
3.59
106
1022
6
42
1.43
0.35
1.0
1.1
—
—
—
0
0
5
79
0.63
0.35
1.4
1.2
7.40
8.99
mm/h
—
5
79
6
43
1.40
0.35
1.0
1.0
—
—
—
0
0
6
43
1.40
0.35
1.0
1.1
—
—
—
0
0
11
82
1.34
0.34
1.2
1.1
—
—
—
0
0
6
45
1.33
0.33
1.0
1.1
—
—
—
0
0
52
463
1.13
0.33
1.3
1.2
—
—
—
0
0
16
198
0.81
0.32
1.1
1.4
—
—
—
0
0
33
285
1.16
0.32
1.3
1.1
0.51
1.60
u/ml
1.05
15
149
16
197
0.81
0.31
1.1
1.4
—
—
—
0
0
7
53
1.32
0.30
1.4
1.6
17.17
14.49
pmol/l
—
7
44
152
1612
0.94
0.30
2.3
2.0
3.33
3.41
ratio
0.38
125
1258
7
100
0.70
0.30
1.1
1.3
—
—
—
0
0
16
195
0.82
0.29
1.1
1.4
—
—
—
0
0
13
103
1.26
0.28
1.5
1.5
87.31
80.11
umol/l
0.27
13
103
20
168
1.19
0.27
2.7
5.2
199.00
41.92
u/ml
—
5
53
14
113
1.24
0.26
1.0
1.0
515.13
295.27
ng/l
—
8
74
14
113
1.24
0.26
1.0
1.0
808.25
711.33
ng/l
—
8
73
16
193
0.83
0.26
1.1
1.4
—
—
—
0
0
16
192
0.83
0.25
1.1
1.4
—
—
—
0
0
16
192
0.83
0.25
1.1
1.4
—
—
—
0
0
25
216
1.16
0.25
1.2
1.0
1.42
2.50
eliau/ml
1.18
11
88
59
540
1.10
0.25
1.3
1.2
0.89
0.90
g/l
0.08
59
540
14
114
1.23
0.25
1.0
1.0
47.80
40.58
ng/l
—
8
73
5
41
1.22
0.22
1.0
1.1
19.82
19.72
mmol/l
—
5
35
5
41
1.22
0.22
1.2
3.0
4.00
5.07
ug/l
—
5
41
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
11
134
0.82
0.20
1.5
1.4
8.55
8.70
mmol/l
0.06
11
129
6
49
1.23
0.20
1.5
1.2
—
—
—
0
0
17
146
1.17
0.19
1.4
1.3
—
—
—
0
0
11
90
1.22
0.19
11.4
13.0
0.56
0.63
mmol/l
0.97
11
84
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
11
90
1.22
0.19
1.1
1.1
—
—
—
0
0
434
4248
1.03
0.19
2.5
2.3
—
—
—
0
0
7
58
1.21
0.18
4.0
3.2
26.71
30.60
umol/l
—
7
41
5
66
0.76
0.17
2.6
2.5
192.20
150.38
nmol/l
—
5
60
6
80
0.75
0.15
2.0
2.4
—
—
—
0
0
51
479
1.07
0.14
1.0
1.1
0.66
0.64
ratio
0.05
13
64
16
141
1.14
0.14
2.2
2.6
—
—
—
0
0
5
48
1.04
0.09
1.0
1.7
—
—
—
0
0
54
517
1.05
0.09
1.1
1.2
1.53
1.55
g/l
0.19
54
517
6
54
1.11
0.09
1.2
1.1
—
—
—
0
0
23
214
1.08
0.08
1.2
1.1
—
—
—
0
0
7
66
1.06
0.08
1.1
1.6
—
—
—
0
0
7
67
1.04
0.08
2.7
1.8
38.60
40.91
g/l
—
7
67
22
206
1.07
0.07
1.7
2.4
8.01
7.35
umol/l
0.10
15
151
8
93
0.86
0.06
1.4
1.1
—
—
—
0
0
66
643
1.03
0.05
1.7
1.8
—
—
—
0
0
185
1827
1.01
0.05
2.0
1.8
1.53
1.46
%
0.72
159
1601
27
260
1.04
0.03
1.2
1.5
0.36
0.31
nmol/l
0.14
20
198
120
1190
1.01
0.01
1.9
1.7
3.38
3.47
mmol/l
0.38
94
838
26
253
1.03
0.01
2.1
1.8
—
—
—
0
0
12
115
1.04
0.00
1.2
1.2
—
—
—
0
0
20
199
1.01
0.00
1.1
1.1
—
—
—
0
0
60
595
1.01
0.00
1.5
1.7
—
—
—
0
0
29
286
1.01
0.00
1.5
1.6
—
—
—
0
0
12
117
1.03
0.00
1.3
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
0.00
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
88
0.91
-0.00
1.6
2.1
31.75
29.10
umol/l
—
8
79
0
5
0.00
-0.00
0.0
1.0
—
14.40
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
1.86
—
0
7
5
55
0.91
-0.00
1.2
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
8.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
7.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
7.63
—
0
8
0
6
0.00
-0.00
0.0
5.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_OTHPIGMENTATION and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_OTHPIGMENTATION | 0.759 [0.68, 0.85] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.564 |
During the follow-up period (1.1.1998 — 31.12.2019), 828 out of 6273 females with L12_OTHPIGMENTATION died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_OTHPIGMENTATION | 0.914 [0.79, 1.06] | 0.229 |
| Birth year | 0.988 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 538 out of 3664 males with L12_OTHPIGMENTATION died.
Mortality risk
Mortality risk for people of age
years, who have L12_OTHPIGMENTATION.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.096% | 0.162% |
| 5 | 0.515% | 1.012% |
| 10 | 1.222% | 2.626% |
| 15 | 2.343% | 5.337% |
| 20 | 4.204% | 9.004% |
Relationships between endpoints
↥Index endpoint: L12_OTHPIGMENTATION – Other disorders of pigmentation
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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