Postinflammatory hyperpigmentation

L12_POSTINFHYPERPIGM

obsolete_incontinentia pigmenti achromians: a dermal melanocytic condition affecting the shoulder area. Nevus of Ito often occurs in association with nevus of Ota in the same patient but is much less common, although the true incidence is unknown.

Suggest a new description

Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L81.0 Cause of death: ICD-10 — L81.0 2 out of 7 registries used, show all original rules.	66
4. Check minimum number of events None	66
5. Include endpoints None	66
6. Filter based on genotype QC (FinnGen only)	55

Control definitions (FinnGen only)

Control exclude: L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: L81
Name in latin: Hyperpigmentatio postinflammatoria cutis

NAME	L12_POSTINFHYPERPIGM
CONTROL_EXCLUDE	L12_OTHERSKINSUBCUTIS
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L810
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L810
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Postinflammatory hyperpigmentation based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	536	307	226
Only index persons	490	288	202
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	49.03	53.76	42.84
Only index persons	50.25	52.89	46.48

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	55	35	20
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	55.41	54.03	57.83

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
61: Matched controls
610

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

L81.0

ICD-10 Finland

Postinflammatory hyperpigmentation

+∞

87.5

TQX10

NOMESCO Finland

Biopsy of skin and subcutaneous tissue

15.3

13.5

JN3AE

NOMESCO Finland

Abdominal ultrasound examination

5.2

6.9

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40768443) Skin Pathology biopsy report

10.07

7.67

1.3

1.1

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

3.82

5.20

2.2

1.9

—

(3023520) Reticulocytes [#/volume] in Blood

3.74

3.94

3.1

3.6

69.58

73.51

e9/l

—

(42870588) Differential panel, method unspecified - Blood

178

2.86

3.93

14.6

5.4

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

284

2.97

3.62

11.2

6.4

10.85

11.86

umol/l

0.26

270

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

4.98

3.49

1.5

1.7

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

3.34

3.35

2.0

1.8

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

2.86

3.12

4.2

2.6

2.64

0.92

e6/l

—

(4035726) Immunohistochemistry procedure

3.68

3.07

2.0

1.3

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

2.89

3.06

3.8

3.1

4.37

5.42

e6/l

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

3.83

3.00

7.0

8.0

24.78

24.26

mmol/l

0.12

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

131

2.54

2.98

5.0

2.3

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

5.92

2.96

2.1

4.0

4.71

0.08

g/l

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

3.17

2.94

2.0

1.8

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

5.12

2.68

1.4

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

5.91

2.61

2.3

4.5

0.00

g/l

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

5.91

2.61

2.3

4.5

0.00

g/l

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

5.91

2.61

2.3

4.5

0.00

g/l

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

2.83

2.59

16.2

8.8

104.86

105.26

mmol/l

0.13

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

3.53

2.58

10.4

8.1

22.39

23.64

mmol/l

—

(3020682) Albumin/Creatinine [Ratio] in Urine

141

2.31

2.47

5.5

3.7

13.10

15.19

mg/mmol

0.09

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

5.41

2.46

2.3

2.6

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

5.41

2.46

2.0

1.6

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

4.02

2.46

11.6

2.7

23.55

24.19

mmol/l

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

4.02

2.46

2.1

1.4

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

4.25

2.33

2.1

2.0

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

2.63

2.28

13.2

4.0

1.19

1.04

mmol/l

0.88

(3000494) Fungus identified in Specimen by Culture

2.56

2.27

1.9

1.3

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

2.56

2.27

3.2

2.0

30.04

29.44

0.14

(3039162) Centromere protein B Ab [Units/volume] in Serum

5.93

2.25

1.0

1.3

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.52

2.20

1.6

1.4

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

3.81

2.12

1.6

1.4

—

(3000991) Gas panel - Venous blood

2.94

2.12

22.4

8.1

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

5.33

2.11

1.2

2.3

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

316

2.22

2.10

19.9

10.0

3.96

4.22

e9/l

0.30

284

(3004588) Protein electrophoresis panel - Serum or Plasma

3.38

2.10

2.1

4.3

—

(3009508) Creatinine [Moles/volume] in Urine

150

2.13

2.07

4.4

3.0

6.00

7.58

mmol/l

1.11

123

(3001604) Monocytes [#/volume] in Blood

279

2.10

2.00

16.1

6.1

0.60

0.56

e9/l

0.32

248

(3006315) Basophils [#/volume] in Blood

280

2.09

1.97

16.0

6.1

0.05

0.04

e9/l

0.53

248

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

2.93

1.96

12.1

8.9

1.06

1.38

—

(3012516) Albumin [Mass/volume] in Urine

136

2.11

1.96

4.7

3.1

58.36

82.37

mg/l

0.29

(3013115) Eosinophils [#/volume] in Blood

292

2.07

1.91

16.5

6.0

0.17

0.19

e9/l

0.39

264

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

4.43

1.86

4.2

3.2

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

255

2.00

1.85

5.0

2.8

—

estimate

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

3.58

1.79

2.2

1.9

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

3.38

1.70

1.3

1.2

—

(3001334) Neutrophil cytoplasmic Ab [Units/volume] in Serum

3.38

1.70

1.8

1.2

—

(3002582) Erythrocytes [#/volume] in Urine

168

1.95

1.70

7.2

2.9

33.84

63.84

e6/l

0.46

134

(36304419) Bacteria [Presence] in Urine

143

1.98

1.68

6.0

2.6

—

estimate

—

(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

3.79

1.65

1.0

1.1

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

2.63

1.60

13.9

8.9

0.46

0.67

—

(1761868) Lipid panel - Serum or Plasma

211

0.46

1.57

5.0

2.7

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

2.46

1.56

1.9

1.4

—

(3021589) Normoblasts [#/volume] in Blood

247

1.85

1.52

18.9

10.8

0.00

e9/l

0.50

202

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

2.05

1.51

1.2

1.3

19.13

9.53

u/ml

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

298

1.86

1.46

10.1

4.6

7.09

6.25

mmol/l

0.97

278

(3003396) Base excess in Arterial blood by calculation

2.27

1.43

10.7

8.2

-2.35

0.24

mmol/l

1.71

(3045414) Leukocytes [Presence] in Urine

2.30

1.36

2.3

2.1

—

0.00

estimate

—

(3018418) pH of Serum or Plasma

161

1.81

1.35

10.3

3.7

7.38

7.40

0.81

122

(3044640) Blood type and Crossmatch panel - Blood

180

1.77

1.31

5.3

2.2

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

2.93

1.31

3.2

1.5

—

(3030467) Casts [#/volume] in Urine by Automated count

155

1.78

1.26

6.0

2.5

0.30

0.36

e6/l

0.09

120

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.13

1.26

2.0

1.6

—

(3042936) Bacteria identified in Isolate by Culture

1.97

1.26

4.1

2.1

—

(3015171) Extractable nuclear Ab [Units/volume] in Serum

2.77

1.24

1.4

—

(40758558) Short blood count panel - Blood

165

1.75

1.23

12.8

7.1

—

(40768804) Tissue Pathology biopsy report

211

1.71

1.21

2.9

2.0

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

131

1.78

1.20

6.0

3.2

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

2.02

1.19

6.1

3.4

10.17

7.94

umol/l

0.15

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

212

1.70

1.19

3.1

1.8

93.56

99.45

pmol/l

0.26

105

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

2.06

1.08

1.9

2.3

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

369

1.69

1.00

3.3

3.4

—

(3018095) Leukocytes [#/volume] in Urine

201

1.62

0.99

7.8

3.6

34.54

112.49

e6/l

0.89

139

(36660697) Celiac disease serology panel - Serum

2.04

0.93

1.1

1.2

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

158

1.61

0.92

2.5

1.9

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

252

1.57

0.91

16.4

6.8

1.21

mmol/l

0.04

216

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.94

0.90

3.1

3.6

—

(3015736) pH of Urine

234

1.56

0.88

4.7

3.2

5.97

6.21

0.53

124

(3023103) Potassium [Moles/volume] in Serum or Plasma

515

2.06

0.87

36.6

15.9

3.96

3.94

mmol/l

0.15

502

(3023368) Bacteria identified in Blood by Culture

143

1.59

0.85

10.7

4.3

—

(3002256) Pathology report gross observation

1.78

0.81

1.5

1.1

—

(3041096) Erythrocytes [Presence] in Urine by Automated

167

0.58

0.81

5.1

3.2

0.00

estimate

—

(3007164) IgA [Mass/volume] in Serum or Plasma

136

1.58

0.80

2.0

1.3

3.15

2.60

g/l

0.35

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

101

1.64

0.80

1.3

1.2

128.98

45.37

iu/ml

—

(3003191) Choriogonadotropin [Presence] in Serum or Plasma

2.18

0.76

2.0

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.09

0.74

1.8

2.0

—

(3045424) Erythrocytes [Presence] in Urine

2.09

0.74

2.8

2.6

—

0.00

estimate

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

519

1.96

0.74

29.8

13.8

26.25

23.53

mg/l

0.23

420

(3016879) Cocaine [Presence] in Urine

2.00

0.72

1.2

1.5

—

(3028300) Cannabinoids [Presence] in Urine

2.00

0.72

1.2

1.5

—

(3027008) Opiates [Presence] in Urine

2.00

0.72

1.2

1.5

—

(3027944) Amphetamines [Presence] in Urine

1.93

0.70

1.2

1.4

—

(3000764) Benzodiazepines [Presence] in Urine

1.93

0.70

1.2

1.4

—

(3022621) pH of Urine by Test strip

1.71

0.69

2.4

2.3

6.21

6.09

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.72

0.63

1.6

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.61

0.0

1.2

—

(40768793) Breast Pathology biopsy report

0.00

0.61

0.0

1.4

—

(3023351) European house dust mite IgE Ab [Units/volume] in Serum

0.00

0.61

0.0

1.2

—

1.63

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.59

0.0

1.7

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

514

1.71

0.58

36.4

15.8

139.40

139.55

mmol/l

0.23

501

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

102

1.48

0.53

1.8

1.4

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.49

0.51

2.8

1.5

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.63

0.51

2.1

2.0

—

(3002385) Erythrocyte [DistWidth] in Red Blood Cells

442

1.40

0.43

35.1

17.5

13.92

13.54

0.79

436

(3003888) Timothy IgE Ab [Units/volume] in Serum

0.00

0.41

0.0

1.1

—

1.53

—

(3010726) Horse dander IgE Ab [Units/volume] in Serum

0.00

0.41

0.0

1.0

—

0.63

—

(3008401) Mugwort IgE Ab [Units/volume] in Serum

0.00

0.41

0.0

1.1

—

1.22

—

(3025941) Bacteria identified in Stool by Culture

1.47

0.40

1.2

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.44

0.36

1.2

1.0

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

131

1.30

0.31

2.7

1.8

—

(40768797) Stomach Pathology biopsy report

1.27

0.28

1.1

1.4

—

(3022145) Colonoscopy Study observation

1.27

0.28

1.4

1.3

—

(3003694) ABO and Rh group [Type] in Blood

181

1.24

0.27

1.3

1.6

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

218

0.81

0.25

7.5

3.6

0.20

0.00

estimate

—

(3026008) Bacteria identified in Urine by Culture

155

1.23

0.23

4.7

2.9

—

(3035350) Ketones [Presence] in Urine by Test strip

293

1.19

0.22

5.9

3.6

0.00

estimate

—

(1616796) Gas panel - Central venous blood

0.00

0.21

0.0

1.8

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.21

0.0

1.9

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.21

0.0

2.9

—

(3035715) Granulocytes [#/volume] in Blood

0.00

0.21

0.0

1.4

—

4.56

—

(3044290) Cell count panel - Cerebral spinal fluid

0.00

0.21

0.0

2.0

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.21

0.0

3.5

—

88.90

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

69.75

—

(3014133) Dog dander IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

5.55

—

(3021601) Nitrite [Presence] in Urine by Test strip

294

1.19

0.21

5.9

3.6

0.00

estimate

—

(21494755) Public health laboratory ask at order entry panel

1.28

0.21

1.0

1.3

—

(3023430) Cat dander IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

15.22

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

186

1.20

0.20

6.6

3.4

41.29

28.99

u/l

0.63

178

(40760892) CBC W Ordered Manual Differential panel - Blood

129

1.22

0.19

9.3

5.0

—

(40761511) CBC panel - Blood by Automated count

544

1.36

0.18

23.3

12.2

—

(3009261) Glucose [Presence] in Urine by Test strip

299

1.15

0.15

6.1

3.6

0.20

0.00

estimate

—

(3003338) MCHC [Entitic Mass/volume] in Red Blood Cells

441

1.18

0.15

43.0

17.6

328.63

332.85

g/l

1.43

441

(3013512) EKG study

163

1.15

0.12

2.5

3.7

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

493

0.88

0.09

5.9

4.5

6.08

5.78

mmol/l

0.45

453

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.79

0.08

2.5

1.5

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

104

1.07

0.01

2.0

2.3

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.01

0.00

2.1

1.8

—

(3029937) Albumin [Presence] in Urine by Test strip

163

0.98

0.00

8.7

3.6

0.00

estimate

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

125

1.05

0.00

1.9

1.7

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.06

0.00

2.3

2.1

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3012413) Glucose [Moles/volume] in Serum or Plasma --2 hours post meal

0.00

0.0

1.7

—

6.75

—

(4146454) Self-monitoring of blood glucose

0.00

0.0

1.7

—

(3019897) Erythrocyte [DistWidth] in Red Blood Cells by Automated count

0.00

0.0

1.2

—

13.17

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

3.3

—

199.33

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

0.0

1.0

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

0.0

1.8

—

6.17

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

2.0

—

2.12

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

21.4

—

1428.29

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.1

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.1

—

(3000492) Spirometry study

1.00

-0.00

1.4

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

-0.00

0.0

1.3

—

(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture

0.00

-0.00

0.0

1.6

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.4

—

(4281824) Cell count and differential, peritoneal fluid

0.00

-0.00

0.0

1.0

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

-0.00

0.0

1.0

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

480

1.00

-0.00

6.3

3.9

1.35

1.23

mmol/l

0.50

441

(3023410) Appearance of Cerebral spinal fluid

0.00

-0.00

0.0

2.1

—

(3018658) Beta 2 glycoprotein 1 IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.85

-0.00

3.0

2.1

—

(3045716) Anion gap in Serum or Plasma by calculation

0.00

-0.00

0.0

1.6

—

11.00

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

10.3

—

793.71

—

(3020876) Protein [Mass/time] in 24 hour Urine

0.00

-0.00

0.0

2.4

—

0.80

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.2

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

4.10

—

(40761536) Microorganisms panel - Urine sediment

0.98

-0.00

7.6

2.9

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

-0.00

0.0

1.1

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.90

-0.00

26.4

6.6

—

(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose

0.00

-0.00

0.0

1.8

—

6.96

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

-0.00

0.0

1.5

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.4

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

-0.00

0.0

1.3

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint L12_POSTINFHYPERPIGM and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_POSTINFHYPERPIGM.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: L12_POSTINFHYPERPIGM – Postinflammatory hyperpigmentation

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Postinflammatory hyperpigmentation

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints