No definition available.
Benign neoplasm: Ill-defined sites within the digestive system
CD2_BENIGN_DIGESTIVE_NOS
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
238 |
4. Check minimum number of eventsNone |
238 |
5. Include endpointsNone |
238 |
6. Filter based on genotype QC (FinnGen only) |
214 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D13
- Name in latin
- Neoplasma benignum systematis digestorii loco male specificato
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Ill-defined sites within the digestive system
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of other and ill-defined parts of digestive system
- Benign neoplasms
- Neoplasms
- Any operation in hilmo
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1435 | 836 | 586 |
| Only index persons | 1139 | 692 | 447 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.02 | 0.03 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 61.79 | 60.50 | 63.56 |
| Only index persons | 60.47 | 58.95 | 62.82 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 214 | 138 | 76 |
| Unadjusted period prevalence (%) | 0.04 | 0.05 | 0.03 |
| Median age at first event (years) | 61.30 | 59.38 | 64.79 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 217
- Matched controls
- 2170
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D13.9
ICD-10 Finland
Benign neoplasm: Ill-defined sites within the digestive system
+∞
241.0
184
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
13.8
30.5
30
25
21199
ICD-8 Finland
Benign neoplasm of other parts of digestive system, Unspecified site
+∞
21.2
20
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
7.0
20.5
34
56
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.1
14.9
101
475
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.1
14.4
46
134
D13.6
ICD-10 Finland
Benign neoplasm: Pancreas
34.3
12.8
16
5
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
9.9
12.6
25
28
UJF32
NOMESCO Finland
Coloscopy
2.8
11.7
82
384
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
15.0
11.2
18
13
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
12.9
11.1
19
16
D13.0
ICD-10 Finland
Benign neoplasm: Oesophagus
63.2
10.7
12
*
TPH07
NOMESCO Finland
Cathetrisation of artery
3.3
10.3
44
154
JN3AD
NOMESCO Finland
Abdominal CT examination
3.2
10.3
48
178
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.4
9.5
101
569
2119X
ICD-9 Finland
Benign neoplasm of other parts of digestive system, Other and unspecified site[NEOPLASMA BENIGNUM ALIUD ORG DIGEST AL DEF SEU NUD]
+∞
9.4
9
*
B01AB04
ATC
dalteparin; parenteral
4.8
9.3
22
50
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.8
9.3
31
92
N02AX02
ATC
tramadol; systemic, rectal
2.4
9.1
118
721
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
8.6
74
375
ZXE00
NOMESCO Finland
One hour or less
2.3
8.4
102
601
A02BC02
ATC
pantoprazole; systemic
2.7
8.3
173
1284
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
4.4
8.0
21
52
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
8.0
67
334
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
7.9
7.8
17
23
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.7
7.6
18
41
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
3.7
7.4
24
70
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
31.1
7.2
9
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.4
7.2
57
276
JAH00
NOMESCO Finland
Laparotomy
5.8
7.1
19
35
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.1
7.0
31
110
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
11.5
6.9
12
11
WX402
NOMESCO Finland
General anaesthesia
2.3
6.9
62
317
130
Kela drug reimbursment
Malignant tumour
2.9
6.5
32
121
JLC30
NOMESCO Finland
Pancreatoduodenectomy
18.7
6.3
9
5
D13.7
ICD-10 Finland
Benign neoplasm: Endocrine pancreas
+∞
6.3
6
*
K86.9
ICD-10 Finland
Disease of pancreas, unspecified
27.5
6.3
8
*
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.8
6.1
34
137
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
40
104
4.49
14.55
2.8
3.1
511.52
2089.15
u/ml
0.53
32
86
63
228
3.48
14.36
3.8
3.5
6.32
6.87
umol/l
0.10
57
205
32
71
5.11
14.06
1.3
1.4
300.15
298.81
ug/g
0.01
23
37
64
239
3.38
13.83
4.6
4.5
13.23
9.40
ug/l
0.28
52
205
49
173
3.37
11.41
3.0
2.5
0.21
0.21
g/l
0.15
49
160
142
915
2.60
10.12
6.9
4.8
35.64
35.19
g/l
0.47
135
863
48
186
3.03
9.47
3.3
2.6
33.81
28.92
u/l
0.58
48
155
19
23
8.94
9.29
5.2
2.2
2.73
4.07
nmol/l
0.80
19
23
102
645
2.10
6.60
3.9
3.4
35.28
30.08
u/l
0.83
96
617
19
55
3.69
5.88
1.2
1.3
—
—
—
0
0
143
1052
2.05
5.85
8.3
7.3
1.21
1.21
mmol/l
0.39
126
909
62
342
2.14
5.59
2.8
2.3
12.02
12.43
umol/l
0.18
56
318
28
113
2.70
5.03
4.1
3.6
24.68
24.47
mmol/l
0.12
28
113
145
1106
1.94
4.94
17.6
10.2
3.98
4.10
e9/l
0.28
117
977
150
1175
1.90
4.50
5.8
5.7
7.05
6.66
mmol/l
0.97
145
1118
88
590
1.83
4.35
4.2
3.2
0.19
0.62
e6/l
2.09
61
428
28
123
2.47
4.25
5.5
6.3
24.29
25.05
mmol/l
0.53
28
123
180
1517
2.09
4.13
14.5
8.5
84.69
79.79
u/l
0.62
174
1435
125
948
1.75
3.94
8.5
6.7
1.21
1.21
mmol/l
0.09
120
878
11
23
4.98
3.93
1.5
1.6
—
—
—
0
0
32
156
2.23
3.85
1.5
1.6
—
—
—
0
0
55
332
1.88
3.72
4.1
3.1
4.57
2.85
e6/l
0.21
21
162
51
307
1.86
3.46
5.3
6.8
103.25
103.88
mmol/l
0.52
51
307
61
395
1.76
3.25
3.7
3.9
167.47
194.04
ng/l
0.07
49
323
119
944
1.58
2.76
3.4
2.9
—
—
estimate
—
0
0
9
221
0.38
2.62
11.6
8.1
—
—
—
0
0
54
360
1.67
2.54
4.2
3.0
0.46
1.08
e6/l
1.80
19
187
7
16
4.48
2.49
1.0
1.1
387.86
329.02
u/l
—
7
16
36
217
1.79
2.42
4.8
3.6
—
—
—
0
0
112
894
1.52
2.41
3.4
2.4
81.68
79.52
nmol/l
0.28
101
799
110
876
1.52
2.39
4.1
2.9
123.93
117.75
ug/l
0.15
103
817
10
33
3.13
2.39
1.5
1.5
—
—
—
0
0
10
33
3.13
2.39
1.5
1.5
—
—
—
0
0
113
907
1.51
2.35
2.4
2.1
101.52
97.41
pmol/l
0.36
65
446
41
259
1.72
2.35
1.8
2.0
—
—
—
0
0
10
35
2.94
2.24
2.0
1.5
226.40
290.86
mu/l
—
10
35
51
349
1.60
2.15
1.8
2.0
—
—
—
0
0
20
106
1.98
1.98
3.8
3.9
4.25
4.34
pmol/l
0.25
20
91
46
316
1.58
1.90
2.1
1.8
29.79
29.19
s
0.37
46
308
38
249
1.64
1.90
4.4
9.4
0.91
1.28
mmol/l
0.24
28
212
86
678
1.44
1.84
4.1
3.9
3.77
10.26
mg/mmol
1.84
52
408
143
1239
1.45
1.82
4.8
3.4
59.04
50.91
u/l
0.44
136
1160
198
1843
1.85
1.81
28.1
17.2
27.72
22.83
mg/l
1.27
179
1527
6
18
3.40
1.76
1.0
1.0
—
—
—
0
0
30
189
1.68
1.74
2.6
2.9
4.16
4.28
kpa
0.20
30
184
40
273
1.57
1.70
1.8
1.9
—
—
—
0
0
126
1078
1.40
1.65
4.2
4.2
0.00
6.85
estimate
0.50
30
237
13
64
2.10
1.57
1.2
2.5
0.00
0.00
g/l
-0.00
13
64
5
15
3.39
1.53
3.2
2.1
13.60
13.48
%
—
5
15
18
102
1.83
1.50
1.1
1.0
—
—
—
0
0
124
1071
1.37
1.46
4.2
4.1
0.00
0.00
estimate
-0.00
26
230
77
619
1.38
1.42
1.8
1.7
21.62
21.61
nmol/l
0.00
70
509
66
522
1.38
1.33
3.1
2.9
323.90
339.22
umol/l
0.57
60
452
125
1096
1.33
1.26
4.5
4.2
0.00
0.02
estimate
0.50
29
222
10
49
2.09
1.24
1.8
1.8
—
—
—
0
0
8
37
2.21
1.23
2.8
3.0
18.56
9.88
pmol/l
—
8
37
13
71
1.88
1.22
1.2
2.5
0.00
0.00
g/l
-0.00
13
64
13
71
1.88
1.22
1.2
1.2
—
—
—
0
0
10
51
2.01
1.13
2.0
1.5
—
—
—
0
0
59
471
1.35
1.11
3.0
2.5
—
—
—
0
0
59
472
1.34
1.10
1.4
1.3
0.54
1.72
u/ml
1.67
16
136
11
59
1.91
1.09
1.4
5.2
1.24
2.80
ratio
—
6
31
10
52
1.97
1.08
1.6
1.5
—
—
—
0
0
7
33
2.16
1.06
3.0
1.2
—
—
nmol/l
—
0
0
96
832
1.28
0.98
2.1
2.0
1.36
1.33
mmol/l
0.15
82
685
17
111
1.58
0.91
1.5
1.4
—
—
—
0
0
6
29
2.10
0.90
1.2
1.0
—
—
—
0
0
8
45
1.81
0.85
1.3
1.1
1.75
2.37
e6/l
—
8
32
8
47
1.73
0.81
1.3
1.2
401.50
148.66
e6/l
—
8
35
11
66
1.70
0.80
1.3
1.8
—
—
—
0
0
6
34
1.79
0.77
1.5
1.7
—
—
—
0
0
17
241
0.68
0.76
4.2
4.9
28.50
32.76
%
—
10
152
9
54
1.70
0.75
1.4
1.2
—
—
—
0
0
9
56
1.63
0.73
1.3
1.6
—
—
—
0
0
5
25
2.02
0.73
1.2
1.3
—
—
—
0
0
9
57
1.60
0.72
1.3
1.8
—
—
—
0
0
192
1845
1.35
0.69
5.2
5.4
6.00
5.99
mmol/l
0.02
180
1695
5
27
1.87
0.69
1.6
1.3
—
—
—
0
0
18
128
1.44
0.68
1.6
1.7
—
—
—
0
0
5
28
1.80
0.66
1.4
1.1
—
—
—
0
0
11
70
1.60
0.66
1.8
1.6
34.34
7.02
u/ml
—
5
13
5
29
1.74
0.64
2.6
3.9
—
—
—
0
0
187
1795
1.30
0.64
28.6
16.9
76.57
77.85
ml/min/173m2
0.36
174
1670
8
49
1.66
0.63
1.6
1.3
—
—
—
0
0
36
292
1.28
0.62
1.6
1.5
—
—
—
0
0
9
59
1.55
0.55
1.4
1.6
—
—
—
0
0
6
39
1.55
0.53
1.7
1.7
—
—
—
0
0
67
595
1.18
0.50
3.9
3.5
0.00
0.00
estimate
-0.00
27
186
14
105
1.36
0.42
2.9
3.1
2.29
2.25
mmol/l
—
8
84
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
5
34
1.48
0.40
1.4
1.7
—
—
—
0
0
16
125
1.30
0.38
2.2
2.7
0.48
0.64
%
1.74
16
125
67
609
1.14
0.37
4.3
4.1
0.00
0.00
estimate
-0.00
27
209
9
71
1.28
0.36
2.1
2.7
—
—
—
0
0
16
127
1.28
0.34
2.2
2.7
1.03
1.18
%
0.27
16
127
15
118
1.29
0.34
1.1
1.1
340.99
142.97
u/ml
—
7
49
13
100
1.32
0.34
1.1
1.3
—
—
—
0
0
51
459
1.15
0.33
2.2
1.7
0.96
1.53
mg/l
1.72
44
373
7
52
1.36
0.31
1.4
1.6
—
—
—
0
0
8
64
1.26
0.28
1.1
1.2
—
—
—
0
0
11
139
0.78
0.28
1.5
1.9
—
—
—
0
0
180
1757
1.14
0.27
6.1
5.6
2.01
1.93
mu/l
0.37
171
1614
59
543
1.12
0.27
6.0
5.8
2.04
2.62
ug/l
0.38
53
482
41
369
1.14
0.27
2.0
1.6
1169.75
1243.29
nmol/l
0.19
32
284
9
74
1.23
0.25
1.6
1.5
—
—
—
0
0
35
313
1.14
0.25
1.5
1.5
—
—
—
0
0
86
813
1.10
0.24
4.3
4.0
0.04
0.00
estimate
0.49
25
191
35
388
0.88
0.24
1.3
1.3
13.09
35.23
iu/ml
2.93
15
131
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
6
49
1.23
0.20
1.3
1.3
—
—
—
0
0
111
1069
1.08
0.19
3.0
2.8
—
—
—
0
0
6
53
1.14
0.19
1.0
1.2
—
—
—
0
0
7
59
1.19
0.18
1.9
1.3
—
—
—
0
0
11
131
0.83
0.17
1.5
1.7
—
—
—
0
0
183
1800
1.11
0.17
7.7
6.6
40.36
39.69
mmol/mol
0.47
176
1682
7
63
1.11
0.17
1.0
1.5
—
—
—
0
0
7
63
1.11
0.17
1.1
1.2
—
—
—
0
0
38
354
1.09
0.14
1.3
1.3
16.26
10.92
u/ml
0.18
17
135
36
335
1.09
0.14
3.3
3.3
0.73
0.76
ug/l
0.04
26
228
174
1763
0.93
0.11
4.1
4.5
1.20
1.27
mmol/l
0.96
162
1609
46
437
1.07
0.11
5.1
4.7
23.36
21.71
%
0.26
19
221
152
1496
1.05
0.10
4.9
4.5
14.81
14.84
pmol/l
0.04
141
1359
5
47
1.07
0.09
1.6
1.6
—
—
—
0
0
7
66
1.06
0.08
1.3
2.1
—
—
—
0
0
15
161
0.93
0.05
1.6
1.5
—
—
—
0
0
183
1843
0.95
0.05
5.0
5.2
1.44
1.52
mmol/l
1.86
170
1689
43
438
0.98
0.01
2.2
1.8
419.79
32231850.27
pmol/l
0.50
34
363
17
177
0.96
0.01
2.5
2.7
78.11
61.84
ml/min/173m2
—
9
76
69
682
1.02
0.01
3.0
3.3
1459.38
1156.77
ng/l
0.20
60
580
12
118
1.02
0.00
5.3
4.0
1.02
1.02
ratio
0.11
12
113
185
1849
1.00
0.00
5.1
5.4
4.48
4.62
mmol/l
1.06
172
1702
82
824
0.99
0.00
4.0
4.0
40.75
42.40
ng/l
0.04
58
616
48
477
1.01
0.00
3.9
4.4
1.02
1.02
kg/l
0.18
32
323
188
1882
0.99
0.00
6.2
6.2
2.58
2.65
mmol/l
0.49
174
1729
0
5
0.00
-0.00
0.0
1.0
—
1.21
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
1.3
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
11.91
—
0
5
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
5
55
0.91
-0.00
1.8
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_DIGESTIVE_NOS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_DIGESTIVE_NOS | 1.908 [1.49, 2.44] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.146 |
During the follow-up period (1.1.1998 — 31.12.2019), 158 out of 500 females with CD2_BENIGN_DIGESTIVE_NOS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_DIGESTIVE_NOS | 1.995 [1.48, 2.68] | < 0.001 |
| Birth year | 0.983 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 139 out of 332 males with CD2_BENIGN_DIGESTIVE_NOS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_DIGESTIVE_NOS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.224% | 0.335% |
| 5 | 1.08% | 2.077% |
| 10 | 2.401% | 5.039% |
| 15 | 4.887% | 9.237% |
| 20 | 8.89% | 15.301% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_DIGESTIVE_NOS – Benign neoplasm: Ill-defined sites within the digestive system
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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