No definition available.
Personality and behavioural disorders due to brain disease, damage and dysfunction
EFO MESH Endpoint Browser PheWeb
F5_PERSBEHORG
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
646 |
4. Check minimum number of eventsNone |
646 |
5. Include endpointsNone |
646 |
6. Filter based on genotype QC (FinnGen only) |
560 |
Control definitions (FinnGen only)
- Control exclude
- F5_ORGANIC
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- F04-F09
- Name in latin
- Perturbationes personae et modi se gerendi a morbo, laesione sive dysfunctione cerebri inductae
Similar endpoints
↥List of similar endpoints to
Personality and behavioural disorders due to brain disease, damage and dysfunction
based on the number of shared cases.
Similar with more cases:
- Organic, including symptomatic, mental disorders
- Psychiatric diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7855 | 2589 | 5124 |
| Only index persons | 5216 | 1732 | 3484 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.07 | 0.14 |
| Only index persons | 0.11 | 0.06 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 53.93 | 56.68 | 52.32 |
| Only index persons | 49.75 | 51.79 | 48.73 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 560 | 197 | 363 |
| Unadjusted period prevalence (%) | 0.13 | 0.07 | 0.17 |
| Median age at first event (years) | 51.36 | 47.13 | 53.66 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 578
- Matched controls
- 5773
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
T90.5
ICD-10 Finland
Sequelae of intracranial injury
62.8
205.8
116
23
F07.9
ICD-10 Finland
Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction
+∞
185.6
168
*
F07.2
ICD-10 Finland
Postconcussional syndrome
+∞
176.3
160
*
N05AX08
ATC
risperidone; systemic
14.7
175.8
184
178
N03AG01
ATC
valproic acid; systemic, rectal
16.2
168.2
161
134
F07.8
ICD-10 Finland
Other organic personality and behavioural disorders due to brain disease, damage and dysfunction
+∞
121.2
112
*
S06.2
ICD-10 Finland
Diffuse brain injury
38.4
113.2
71
21
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
12.4
112.7
123
123
F03
ICD-10 Finland
Unspecified dementia
49.5
112.4
66
15
N05AH03
ATC
olanzapine; systemic
10.6
107.7
133
158
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
9.7
106.2
143
190
G40.9
ICD-10 Finland
Epilepsy, unspecified
16.1
103.7
94
69
S06.3
ICD-10 Finland
Focal brain injury
27.9
96.6
67
27
N05AD01
ATC
haloperidol; systemic
16.6
92.9
82
57
F07.0
ICD-10 Finland
Organic personality disorder
+∞
84.4
79
*
N05AH04
ATC
quetiapine; oral
5.5
81.4
213
550
N06AB04
ATC
citalopram; systemic
4.9
72.3
225
663
N05AA02
ATC
levomepromazine; systemic
9.7
71.3
90
108
N03AF02
ATC
oxcarbazepine; oral
12.1
68.2
72
67
F32.9
ICD-10 Finland
Depressive episode, unspecified
5.7
67.6
155
351
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
16.4
66.4
58
39
F29
ICD-10 Finland
Unspecified nonorganic psychosis
9.8
61.6
76
88
XA800
NOMESCO Finland
Neuropsychological investigation
9.1
58.9
77
96
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
23.1
55.5
41
19
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
10.4
55.1
64
68
N03AF01
ATC
carbamazepine; oral, rectal
7.2
55.1
90
145
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
13.5
54.5
53
43
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
6.2
54.3
104
197
T36
ICD-10 Finland
Poisoning by systemic antibiotics
8.6
54.2
74
97
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
12.8
53.9
54
46
R41.0
ICD-10 Finland
Disorientation, unspecified
14.3
53.4
50
38
R56.8
ICD-10 Finland
Other and unspecified convulsions
7.3
53.0
85
134
N05BA01
ATC
diazepam; systemic, rectal
4.5
51.8
158
446
N03AX14
ATC
levetiracetam; systemic
11.6
51.3
55
52
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
5.4
47.8
107
233
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
5.4
46.0
101
216
N05CD07
ATC
temazepam; oral
4.4
45.0
138
388
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
9.3
44.5
56
66
N03AB02
ATC
phenytoin; systemic
18.2
43.9
36
21
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
5.8
43.1
86
168
N05BA06
ATC
lorazepam; systemic, sublingual
6.3
42.0
76
135
F10.20
ICD-10 Finland
Alcohol dependence currently independent
10.2
41.1
48
51
N05BA04
ATC
oxazepam; oral
3.3
41.0
220
895
A28
ICPC
Limited function/disability NOS
3.7
39.5
160
543
F06.9
ICD-10 Finland
Unspecified mental disorder due to brain damage and dysfunction and to physical disease
+∞
39.0
37
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.5
38.0
173
632
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.1
37.7
251
1148
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
4.9
37.5
92
215
N03AX09
ATC
lamotrigine; oral
6.2
37.4
68
121
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
11.9
37.4
39
35
F05.9
ICD-10 Finland
Delirium, unspecified
139.0
37.2
39
*
AA1AD
NOMESCO Finland
CT of head and brain
3.1
36.4
239
1081
Z2445
NOMESCO Finland
Psychologist
6.8
36.2
60
97
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
13.8
35.9
34
26
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
+∞
33.7
32
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.3
31.9
91
239
N05AF03
ATC
chlorprothixene; systemic
8.1
31.8
44
58
F07.1
ICD-10 Finland
Postencephalitic syndrome
+∞
31.5
30
*
W19
ICD-10 Finland
Unspecified fall
3.9
29.2
97
284
N06AX16
ATC
venlafaxine; oral
3.5
29.1
121
411
V49.9
ICD-10 Finland
Car occupant [any] injured in unspecified traffic accident
6.0
29.0
54
98
N06AX11
ATC
mirtazapine; oral
2.7
28.7
245
1241
N04AA02
ATC
biperiden; systemic
10.5
28.5
32
32
A06AD11
ATC
lactulose; oral
3.2
28.4
134
492
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
6.8
28.2
46
73
N05BE01
ATC
buspirone; oral
6.7
27.8
46
74
S06.0
ICD-10 Finland
Concussion
3.5
27.6
108
352
N05AX12
ATC
aripiprazole; systemic
5.8
27.4
52
96
S01.0
ICD-10 Finland
Open wound of scalp
4.0
26.8
85
240
N06DX01
ATC
memantine; oral
36.0
26.8
34
10
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
10.5
26.7
30
30
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.6
26.5
217
1068
G30.1
ICD-10 Finland
Alzheimer disease with late onset
28.5
26.1
35
13
F10.25
ICD-10 Finland
Alcohol dependence continuous use
8.5
25.8
34
42
N03AE01
ATC
clonazepam; systemic
4.9
25.8
60
133
N06DA03
ATC
rivastigmine; oral, transdermal
46.6
25.8
31
7
N06DA02
ATC
donepezil; oral
31.7
25.3
33
11
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.9
24.4
80
231
N06AB03
ATC
fluoxetine; oral
3.2
24.2
110
392
N07BB01
ATC
disulfiram; oral
4.7
23.9
58
133
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.2
23.7
109
391
F60.9
ICD-10 Finland
Personality disorder, unspecified
19.5
23.3
35
19
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
9.4
23.1
28
31
N05CF01
ATC
zopiclone; oral
2.4
23.1
238
1289
NA1AD
NOMESCO Finland
Cervical spine CT examination
4.5
22.2
57
137
X59
ICD-10 Finland
Exposure to unspecified factor
2.7
21.9
149
661
F05.8
ICD-10 Finland
Other delirium
83.3
21.8
24
*
N05BA09
ATC
clobazam; oral
27.6
21.5
29
11
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
24.2
21.5
30
13
N06AB06
ATC
sertraline; oral
3.2
21.4
94
327
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.7
21.4
142
621
Z2446
NOMESCO Finland
Social worker
3.7
21.1
71
208
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
4.6
21.1
53
125
N06AX21
ATC
duloxetine; oral
3.2
21.0
92
320
3101A
ICD-9 Finland
Specific nonpsychotic mental disorders following organic brain damage, Organic personality syndrome
+∞
20.9
20
*
F01.9
ICD-10 Finland
Vascular dementia, unspecified
+∞
20.9
20
*
T74.1
ICD-10 Finland
Physical abuse
7.7
20.9
30
41
N05AB03
ATC
perphenazine; systemic, rectal
5.6
20.9
41
78
183
Kela drug reimbursment
Lamotrigin and topiramate
19.2
20.6
31
17
N06AX03
ATC
mianserin; oral
4.6
20.0
49
113
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
3.4
20.0
78
252
N06AB10
ATC
escitalopram; oral
2.6
19.8
143
649
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
8.7
19.4
25
30
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
3.4
19.3
77
252
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
6.3
19.2
33
55
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.3
18.9
76
250
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
8.4
18.9
25
31
N05AH02
ATC
clozapine; systemic
7.0
18.8
29
43
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
6.7
18.5
30
47
N05AC02
ATC
thioridazine; oral
8.1
18.4
25
32
F10.09
ICD-10 Finland
Alcohol intoxication UNS
6.0
17.7
32
56
N05BA02
ATC
chlordiazepoxide; systemic
5.5
17.7
35
67
L28
ICPC
Limited function/disability (L)
2.5
17.6
129
587
F22.0
ICD-10 Finland
Delusional disorder
14.6
16.9
28
20
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.6
16.8
118
525
F06.7
ICD-10 Finland
Mild cognitive disorder
15.7
16.8
27
18
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
4.5
16.7
42
99
85190
ICD-8 Finland
Cerebral laceration and contusion, Late effect
92.7
16.6
18
*
AAD05
NOMESCO Finland
Evacuation of acute subdural haematoma
28.5
16.6
22
8
P29
ICPC
Psychological sympt/compl other
3.5
16.5
61
190
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
5.7
16.3
31
57
N05AN01
ATC
lithium; oral
5.8
16.2
30
54
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.0
16.1
77
280
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
4.4
16.0
41
98
P20
ICPC
Memory disturbance
3.0
15.9
77
282
R53
ICD-10 Finland
Malaise and fatigue
2.2
15.9
170
910
F20.9
ICD-10 Finland
Schizophrenia, unspecified
6.1
15.8
28
48
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.6
15.7
101
430
F06.32
ICD-10 Finland
Organic depression
+∞
15.7
15
*
TAB00
NOMESCO Finland
Lumbar puncture
4.4
15.5
40
96
N05AD03
ATC
melperone; systemic
12.8
15.5
27
22
N05CD02
ATC
nitrazepam; oral
6.7
15.0
24
37
OAB43, ,
SPAT
0.2
14.9
29
1053
G40
ICD-10 Finland
Epilepsy
17.0
14.9
23
14
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.7
14.8
88
360
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
4.0
14.6
43
114
29350
ICD-8 Finland
Psychosis associated with other cerebral condition, Brain trauma
+∞
14.6
14
*
F10.24
ICD-10 Finland
Alcohol depence active use
6.0
14.6
26
45
F06.8
ICD-10 Finland
Other specified mental disorders due to brain damage and dysfunction and to physical disease
153.5
14.5
15
*
S06.4
ICD-10 Finland
Epidural haemorrhage
153.5
14.5
15
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.7
14.4
48
139
N03AX18
ATC
lacosamide; systemic
17.5
14.4
22
13
S06.9
ICD-10 Finland
Intracranial injury, unspecified
19.7
14.3
21
11
ZXD05
NOMESCO Finland
Urgent procedure
2.1
14.1
195
1143
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.8
14.1
74
283
S72.0
ICD-10 Finland
Fracture of neck of femur
4.4
14.1
36
86
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
30.9
13.9
18
6
F99
ICD-10 Finland
Mental disorder, not otherwise specified
6.2
13.9
24
40
N03AX11
ATC
topiramate; oral
5.3
13.7
28
55
EBA15
NOMESCO Finland
Extraction of multiple teeth
4.2
13.7
37
92
N03AX16
ATC
[U] pregabalin
2.2
13.7
149
797
N05AF05
ATC
zuclopenthixol; systemic
15.2
13.7
22
15
113
Kela drug reimbursment
Anxiety disorders associated with mental retardation
76.9
13.6
15
*
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.9
13.6
68
253
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
143.1
13.5
14
*
F06.2
ICD-10 Finland
Organic delusional [schizophrenia-like] disorder
143.1
13.5
14
*
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.7
13.4
44
126
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
26.4
13.4
18
7
78020
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Convulsions
21.7
13.4
19
9
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.0
13.3
63
227
ZXD35
NOMESCO Finland
Usual procedure
4.4
13.3
34
81
P99
ICPC
Psychological disorders other
4.7
13.2
31
69
N06AX05
ATC
trazodone; oral
4.8
13.2
30
65
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
15.5
13.2
21
14
G41.9
ICD-10 Finland
Status epilepticus, unspecified
32.8
12.6
16
5
R4120
NOMESCO Finland
Occupational therapy
3.2
12.5
53
179
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
14.7
12.3
20
14
N06AA09
ATC
amitriptyline; systemic
2.8
12.3
66
255
W17
ICD-10 Finland
Other fall from one level to another
3.8
12.1
37
101
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
5.5
11.9
23
43
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
4.0
11.8
34
89
W00
ICD-10 Finland
Fall on same level involving ice and snow
2.5
11.7
80
349
85100
ICD-8 Finland
Cerebral laceration and contusion, Without mention of open intracranial wound
23.4
11.6
16
7
N06AG02
ATC
moclobemide; oral
3.7
11.6
38
109
F05.1
ICD-10 Finland
Delirium superimposed on dementia
+∞
11.5
11
*
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.9
11.4
56
206
SPAT1229
SPAT
Assessment of need for aid
3.0
11.4
51
178
W10
ICD-10 Finland
Fall on and from stairs and steps
3.2
11.4
46
151
R40.2
ICD-10 Finland
Coma, unspecified
9.9
11.3
22
23
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
13.0
11.2
19
15
N88
ICPC
Epilepsy
25.6
11.2
15
6
N28
ICPC
Limited function/disability (N)
8.8
11.1
23
27
N05AB01
ATC
dixyrazine; systemic
9.5
11.1
22
24
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
5.0
11.0
24
50
R51.80
ICD-10 Finland
Headache
2.2
10.9
103
517
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
9.8
10.8
21
22
Z02.4
ICD-10 Finland
Examination for driving licence
0.4
10.7
57
1258
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
9.4
10.6
21
23
L89
ICD-10 Finland
Decubitus ulcer and pressure area
5.6
10.4
20
37
N06DA04
ATC
galantamine; oral
111.8
10.4
11
*
F02.89*G40.9
ICD-10 Finland
Dementia in epilepsy
+∞
10.4
10
*
F06.0
ICD-10 Finland
Organic hallucinosis
+∞
10.4
10
*
F06.39
ICD-10 Finland
Organic mood syndrome UNS
+∞
10.4
10
*
9070A
ICD-9 Finland
Late effects of injuries to the nervous system, Late effect of intracranial injury without mention of skull fracture
+∞
10.4
10
*
29399
ICD-8 Finland
Psychosis associated with other cerebral condition, Other and unspecified cerebral condition
+∞
10.4
10
*
ZY010
NOMESCO Finland
Hospital outpatient
3.2
10.4
43
143
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
3.0
10.4
46
160
34599
ICD-8 Finland
Epilepsy, Other and unspecified
19.2
10.3
15
8
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.8
10.3
31
84
2989X
ICD-9 Finland
Other nonorganic psychoses, Unspecified psychosis
13.4
10.2
17
13
WX892
NOMESCO Finland
Monitored bed care
2.6
10.2
61
249
R42
ICD-10 Finland
Dizziness and giddiness
2.0
10.2
139
800
IGY99
NOMESCO Finland
Other psychiatric treatment contact
5.1
10.1
21
42
R11
ICD-10 Finland
Nausea and vomiting
2.6
10.1
63
263
S02.10
ICD-10 Finland
Fracture of base of skull, closed
17.1
9.9
15
9
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
3.5
9.9
34
101
K08.3
ICD-10 Finland
Retained dental root
2.6
9.8
58
235
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
9.0
9.8
20
23
F43.1
ICD-10 Finland
Post-traumatic stress disorder
4.8
9.8
22
47
WX730
NOMESCO Finland
Conventional respirator
7.6
9.8
22
30
S72.1
ICD-10 Finland
Pertrochanteric fracture
5.4
9.7
19
36
G30.0
ICD-10 Finland
Alzheimer disease with early onset
55.9
9.7
11
*
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
4.4
9.7
24
56
F39
ICD-10 Finland
Unspecified mood [affective] disorder
7.3
9.6
22
31
S06.6
ICD-10 Finland
Traumatic subarachnoid haemorrhage
10.3
9.6
18
18
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.2
9.6
87
429
G40.89
ICD-10 Finland
Other epilepsy
15.3
9.5
15
10
Z3226
NOMESCO Finland
Physiotherapist
2.0
9.5
113
618
G31.0
ICD-10 Finland
Circumscribed brain atrophy
30.5
9.4
12
*
IGY02
NOMESCO Finland
Psychiatric monitoring contact
3.9
9.4
28
75
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
8.2
9.4
20
25
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
12.6
9.4
16
13
F05.0
ICD-10 Finland
Delirium not superimposed on dementia, so described
+∞
9.4
9
*
AAK00
NOMESCO Finland
Cranioplasty
+∞
9.4
9
*
A86
ICD-10 Finland
Unspecified viral encephalitis
22.1
9.4
13
6
S00.0
ICD-10 Finland
Superficial injury of scalp
4.6
9.4
22
49
N80
ICPC
Head injury other
5.0
9.4
20
41
A04
ICPC
Weakness/tiredness general
2.1
9.2
93
478
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
3.0
9.1
42
149
G72.8
ICD-10 Finland
Other specified myopathies
4.9
9.1
20
42
N06AA12
ATC
doxepin; systemic
2.9
9.1
43
155
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
18.9
9.0
13
7
EBA00
NOMESCO Finland
Extraction of tooth
1.7
8.9
207
1396
N06AB08
ATC
fluvoxamine; oral
4.0
8.9
25
64
S02.20
ICD-10 Finland
Fracture of nasal bones, closed
4.8
8.9
20
43
N06AA06
ATC
trimipramine; systemic
4.1
8.9
24
60
F32.1
ICD-10 Finland
Moderate depressive episode
2.9
8.7
42
153
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
7.8
8.7
19
25
N05AA01
ATC
chlorpromazine; systemic, rectal
7.8
8.7
19
25
N29
ICPC
Neurological sympt/complt other
7.8
8.7
19
25
N02AA05
ATC
oxycodone; systemic
2.0
8.7
114
644
A01
ICPC
Pain general/multiple sites
2.4
8.7
65
295
Z02.7
ICD-10 Finland
Issue of medical certificate
2.6
8.6
52
213
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
4.9
8.6
19
40
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
3.5
8.6
29
85
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
4.2
8.6
23
57
R55
ICD-10 Finland
Syncope and collapse
2.2
8.6
74
357
R52.2
ICD-10 Finland
Other chronic pain
3.3
8.5
32
101
R41.3
ICD-10 Finland
Other amnesia
4.4
8.5
21
49
N03AX12
ATC
[U] gabapentin; oral
2.0
8.4
99
537
S06.8
ICD-10 Finland
Other intracranial injuries
91.2
8.4
9
*
N30.0
ICD-10 Finland
Acute cystitis
2.1
8.4
85
436
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
8.0
8.4
18
23
SPAT1254
SPAT
Administration of medicine
2.1
8.4
82
416
AAD15
NOMESCO Finland
Evacuation of traumatic intracerebral haematoma
+∞
8.3
8
*
29320
ICD-8 Finland
Psychosis associated with other cerebral condition, Epilepsy
+∞
8.3
8
*
80090
ICD-8 Finland
Fracture of vault of skull, Late effect
+∞
8.3
8
*
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
8.7
8.3
17
20
S60.2
ICD-10 Finland
Contusion of other parts of wrist and hand
2.9
8.3
38
135
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
4.3
8.2
21
50
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
3.5
8.2
28
83
Y94.0
ICD-10 Finland
Accident at home
4.6
8.2
19
42
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.9
8.1
24
64
ZY000
NOMESCO Finland
Hospital inpatient
8.3
8.1
17
21
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.2
8.1
73
358
Y04.2
ICD-10 Finland
Assault by bodily force by friend
33.8
8.1
10
*
3459X
ICD-9 Finland
Epilepsy, unspecified
33.8
8.1
10
*
TKC20
NOMESCO Finland
Catheterisation of bladder
2.4
8.1
55
239
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.2
8.0
68
325
Z72.8
ICD-10 Finland
Other problems related to lifestyle
22.4
8.0
11
5
X58
ICD-10 Finland
Exposure to other specified factors
2.0
8.0
96
525
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
8.0
199
1362
SPAT1167
SPAT
Insertion of urinary catheter
3.8
8.0
24
65
N06AB05
ATC
paroxetine; oral
2.8
7.9
40
150
TNX34
NOMESCO Finland
Major custom molded cast, unspecified region
8.6
7.8
16
19
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.0
7.8
89
477
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.0
7.8
94
514
SPAT1301
SPAT
No procedures
1.7
7.8
165
1078
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.4
7.8
54
237
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
7.8
147
930
W22
ICD-10 Finland
Striking against or struck by other object(s)
2.5
7.7
50
212
F61.0
ICD-10 Finland
Mixed personality disorders
6.0
7.7
20
34
U04
ICPC
Incontinence urine
2.9
7.7
37
135
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.1
7.7
74
373
G30.8
ICD-10 Finland
Other Alzheimer disease
18.6
7.6
11
6
F60.8
ICD-10 Finland
Other specific personality disorders
18.6
7.6
11
6
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
18.6
7.6
11
6
A41.9
ICD-10 Finland
Sepsis, unspecified
3.3
7.6
28
87
T91.8
ICD-10 Finland
Sequelae of other specified injuries of neck and trunk
25.4
7.6
10
*
SPAT1240
SPAT
Therapeutic discussion
2.3
7.6
58
266
SPAT1234
SPAT
Support of social functional capacity
3.2
7.5
30
98
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
7.5
107
620
S00.1
ICD-10 Finland
Contusion of eyelid and periocular area
4.5
7.5
18
41
N03AG04
ATC
vigabatrin; oral
81.0
7.4
8
*
31099
ICD-8 Finland
Borderline mental retardation, Other and unspecified
81.0
7.4
8
*
N05AC01
ATC
periciazine; systemic
13.6
7.4
12
9
SPAT1360
SPAT
Extensive global examination
2.7
7.3
39
150
K92.0
ICD-10 Finland
Haematemesis
3.6
7.3
24
69
F32
ICD-10 Finland
Depressive episode
3.0
7.3
33
116
S42.0
ICD-10 Finland
Fracture of clavicle
3.5
7.3
25
74
R1250
NOMESCO Finland
Evaluation of functional capability
4.2
7.3
19
46
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
9.5
7.3
14
15
G21.1
ICD-10 Finland
Other drug-induced secondary parkinsonism
+∞
7.3
7
*
29398
ICD-8 Finland
Psychosis associated with other cerebral condition, Alia definita
+∞
7.3
7
*
F06.6
ICD-10 Finland
Organic emotionally labile [asthenic] disorder
+∞
7.3
7
*
V89
ICD-10 Finland
Motor- or nonmotor-vehicle accident, type of vehicle unspecified
+∞
7.3
7
*
A46
ICD-10 Finland
Erysipelas
1.9
7.3
96
541
S22.3
ICD-10 Finland
Fracture of rib
2.3
7.3
56
257
S52.0
ICD-10 Finland
Fracture of upper end of ulna
6.4
7.3
18
29
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
3.0
7.3
32
111
G40.10
ICD-10 Finland
Simple partial seizures
16.0
7.2
11
7
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
7.4
7.2
16
22
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
7.4
7.2
16
22
P76
ICPC
Depressive disorder
2.6
7.2
43
176
R63.1
ICD-10 Finland
Polydipsia
30.4
7.2
9
*
G40.00
ICD-10 Finland
Benign childhood epilepsy with centrotemporal EEG spikes
30.4
7.2
9
*
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
30.4
7.2
9
*
34510
ICD-8 Finland
Epilepsy, """"Grand mal""""
30.4
7.2
9
*
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
6.7
7.1
17
26
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
8.1
7.1
15
19
S82.1
ICD-10 Finland
Fracture of upper end of tibia
6.1
7.1
18
30
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
6.1
7.1
18
30
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
7.1
101
584
2968A
ICD-9 Finland
Affective psychoses, Manic-depressive psychosis, other and unspecified
8.9
7.1
14
16
3018X
ICD-9 Finland
Personality disorders, Other personality disorders[MUU TAI SEKAMUOTOINEN PERSOONALLISUUSHÄIRIÖ]
10.2
7.1
13
13
C03CA01
ATC
furosemide; systemic
1.7
7.0
188
1304
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.8
6.9
35
131
F31.1
ICD-10 Finland
Bipolar affective disorder, current episode manic without psychotic symptoms
7.7
6.9
15
20
H53.4
ICD-10 Finland
Visual field defects
4.1
6.9
19
48
SPAT1216
SPAT
Assessment of functional ability
2.0
6.9
80
431
30180
ICD-8 Finland
Personality disorders, Immatura
14.0
6.9
11
8
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.6
6.9
39
155
S01.3
ICD-10 Finland
Open wound of ear
6.8
6.8
16
24
OAB95, ,
SPAT
0.1
6.8
*
251
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.0
6.8
30
104
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
5.8
6.8
18
32
N05BA12
ATC
alprazolam; oral
2.2
6.8
61
299
G31.9
ICD-10 Finland
Degenerative disease of nervous system, unspecified
40.5
6.8
8
*
G05.1*B00.4
ICD-10 Finland
Herpesviral meningoencephalitis
40.5
6.8
8
*
G31.8
ICD-10 Finland
Other specified degenerative diseases of nervous system
40.5
6.8
8
*
E9509
ICD-8 Finland
Suicide and self-inflicted poisoning by solid or liquid substances, Other and unspecified solid and liquid substances
16.9
6.8
10
6
R47.0
ICD-10 Finland
Dysphasia and aphasia
7.3
6.7
15
21
N05BB01
ATC
hydroxyzine; systemic
2.6
6.7
39
157
F34.1
ICD-10 Finland
Dysthymia
3.0
6.7
30
105
P15
ICPC
Chronic alcohol abuse
3.1
6.7
27
89
29599
ICD-8 Finland
Schizophrenia, Unspecified type
22.8
6.7
9
*
F22.9
ICD-10 Finland
Persistent delusional disorder, unspecified
22.8
6.7
9
*
N05CD08
ATC
midazolam; nasal, systemic
3.8
6.7
20
54
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
6.5
6.7
16
25
SPAT1251
SPAT
Organisation of medication
3.2
6.7
26
84
R4150
NOMESCO Finland
Neuropsychological rehabilitation
7.9
6.6
14
18
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.9
6.6
30
106
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
3.4
6.6
23
69
F20.5
ICD-10 Finland
Residual schizophrenia
12.4
6.6
11
9
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.6
6.6
39
159
S82.6
ICD-10 Finland
Fracture of lateral malleolus
2.6
6.6
39
159
K90
ICPC
Stroke/cerebrovascular accident
3.6
6.5
21
60
Z3231
NOMESCO Finland
Registered nurse
1.7
6.5
156
1049
S62.6
ICD-10 Finland
Fracture of other finger
2.8
6.5
31
113
OAA80, ,
SPAT
0.2
6.5
8
335
Y04.9
ICD-10 Finland
Assault by bodily force by unknown person
7.5
6.4
14
19
5AB01, ,
NOMESCO Finland
70.5
6.4
7
*
ADB00
NOMESCO Finland
Implantation of vagus nerve stimulating device
70.5
6.4
7
*
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
3.8
6.4
19
51
D12
ICPC
Constipation
3.0
6.4
28
97
Y96.9
ICD-10 Finland
Unspecified type of accident
4.1
6.4
17
42
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
8.3
6.4
13
16
Y09
ICD-10 Finland
Assault by unspecified means
11.2
6.3
11
10
S42.2
ICD-10 Finland
Fracture of upper end of humerus
2.9
6.3
28
98
N03AX15
ATC
zonisamide; oral
18.2
6.3
9
5
S02.11
ICD-10 Finland
Fracture of base of skull, open
18.2
6.3
9
5
29330
ICD-8 Finland
Psychosis associated with other cerebral condition, Intercranial neoplasm
+∞
6.3
6
*
F06.33
ICD-10 Finland
Organic mood syndrome
+∞
6.3
6
*
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
+∞
6.3
6
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
6.3
194
1387
H03AA01
ATC
levothyroxine sodium; systemic
1.8
6.2
109
670
F70.9
ICD-10 Finland
Mild mental retardation, Without mention of impairment of behaviour
27.0
6.2
8
*
RS140, ,
NOMESCO Finland
27.0
6.2
8
*
3454A
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[EPILEPSIA GENERALISATA SECUNDARIA]
27.0
6.2
8
*
R45.1
ICD-10 Finland
Restlessness and agitation
27.0
6.2
8
*
3451A
ICD-9 Finland
Epilepsy, Generalised convulsive epilepsy
27.0
6.2
8
*
M03BX01
ATC
baclofen; systemic
5.1
6.2
18
36
N06AX12
ATC
bupropion; oral
2.4
6.2
43
189
N18
ICPC
Paralysis/weakness
4.2
6.1
16
39
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
4.2
6.1
16
39
F19.20
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances currently independent
12.7
6.1
10
8
G40.09
ICD-10 Finland
Other or unspecified partial (focal) idiopathic epilepsy or epileptic syndrome with local onset
12.7
6.1
10
8
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
6.1
82
465
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
3.7
6.1
19
53
3018D
ICD-9 Finland
Personality disorders, Other personality disorders[EPÄVAKAA PERSOONALLISUUS]
10.2
6.0
11
11
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.5
6.0
20
58
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
5.3
6.0
17
33
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
81
63
14.77
86.11
4.9
6.0
350.06
361.04
umol/l
0.18
67
55
157
722
2.61
21.37
1.9
1.7
1030.73
1123.57
nmol/l
0.72
115
554
305
2114
1.93
13.45
8.2
7.5
1.21
1.21
mmol/l
0.26
278
1952
330
2355
1.93
13.26
8.4
8.0
1.21
1.21
mmol/l
0.65
285
2037
152
837
2.10
12.86
2.3
1.9
—
—
—
0
0
224
1488
1.82
10.55
3.5
2.2
533.62
312.41
u/l
0.56
212
1415
23
48
4.94
10.55
1.6
1.1
283.00
278.97
mosm/kgh2o
0.26
17
37
117
626
2.09
10.49
2.2
1.8
—
—
—
0
0
111
585
2.11
10.35
2.3
1.9
—
—
—
0
0
68
303
2.41
9.46
1.7
1.6
—
—
—
0
0
225
1559
1.72
8.79
3.3
2.8
50.62
64.63
u/l
2.69
208
1457
389
4517
0.57
8.52
5.0
5.2
1.34
1.40
mmol/l
1.78
346
4202
401
4603
0.58
8.06
5.7
6.0
2.68
2.67
mmol/l
0.05
361
4297
17
24
7.26
7.52
1.2
2.2
136.71
61.50
umol/l
—
7
14
396
4537
0.59
7.41
4.9
5.3
4.48
4.54
mmol/l
0.57
354
4250
374
4343
0.60
7.34
4.2
4.4
1.44
1.32
mmol/l
2.01
330
4014
180
1222
1.68
7.32
2.4
2.3
2.67
2.94
mg/l
0.91
150
1052
134
845
1.76
7.09
3.3
3.8
0.82
0.82
mmol/l
0.04
122
806
272
2078
1.58
6.72
6.3
5.5
34.15
35.66
g/l
3.46
249
1954
26
84
3.19
6.65
1.8
1.3
22.78
15.93
e6/l
0.18
18
61
75
1279
0.52
6.43
2.4
3.1
0.63
0.80
ug/l
1.62
46
805
103
620
1.80
6.33
2.3
1.9
1.79
1.50
%
1.69
84
549
84
475
1.90
6.30
2.0
2.2
357.59
379.16
nmol/l
0.46
75
450
99
595
1.80
6.11
9.7
9.7
2.54
0.83
mmol/l
3.72
83
501
99
600
1.78
5.94
9.6
9.6
5.44
5.14
kpa
1.86
94
579
99
601
1.78
5.90
9.6
9.6
11.84
12.18
kpa
0.27
94
582
121
782
1.69
5.77
2.3
2.7
2.42
2.28
g/l
1.78
111
732
114
732
1.69
5.56
2.3
2.7
19.63
23.52
%
2.65
105
694
153
1061
1.60
5.50
4.7
3.9
1.02
1.02
kg/l
0.59
109
710
359
2997
1.52
5.45
6.9
4.5
653.27
1643.94
e6/l
0.36
11
54
323
2639
1.50
5.43
7.0
7.4
9.64
12.15
umol/l
7.67
301
2519
50
248
2.11
5.41
1.9
1.4
—
—
—
0
0
261
2046
1.50
5.34
2.4
2.1
93.50
96.16
pmol/l
0.40
157
1106
290
2328
1.49
5.25
16.1
14.7
1.22
1.27
inr
0.86
263
1933
180
1319
1.53
5.02
1.9
1.7
17.56
20.21
nmol/l
1.71
158
1108
121
1707
0.63
4.81
4.4
4.3
21.95
21.53
%
0.12
51
799
205
1556
1.49
4.79
3.7
3.7
2.33
2.35
mmol/l
1.06
175
1410
81
493
1.75
4.77
4.4
3.4
—
—
—
0
0
341
2864
1.46
4.69
8.6
5.6
6.65
6.73
mmol/l
0.27
325
2733
134
934
1.56
4.64
1.8
1.8
463.56
21696178.80
pmol/l
0.74
113
802
11
19
5.87
4.45
3.4
2.9
8.97
10.67
kpa
1.50
11
19
11
19
5.87
4.45
3.4
2.9
5.57
4.68
kpa
2.13
11
19
241
1909
1.45
4.45
5.3
3.8
31.54
66.05
ng/l
0.63
185
1394
326
2734
1.44
4.39
12.7
10.6
4.55
4.10
e9/l
2.21
282
2386
28
119
2.42
4.38
2.9
2.3
134.77
130.83
g/l
0.35
22
91
80
497
1.71
4.38
3.7
4.1
2.42
1.82
mmol/l
0.71
69
426
104
696
1.60
4.26
5.0
6.6
1.05
1.04
mmol/l
0.06
98
652
247
1981
1.43
4.19
2.8
2.5
72.41
76.63
nmol/l
1.27
220
1782
218
1711
1.44
4.16
4.6
3.6
31.60
34.99
u/l
0.76
204
1620
11
21
5.31
4.15
1.8
1.5
1.28
1.04
nmol/l
—
5
15
78
498
1.65
3.86
2.2
2.6
0.21
0.21
g/l
0.07
71
464
133
963
1.49
3.81
4.1
4.1
1293.87
326.23
ng/l
0.36
104
770
32
154
2.14
3.79
1.4
1.2
—
—
—
0
0
408
3614
1.43
3.76
9.5
9.1
79.92
80.32
u/l
0.07
382
3428
9
16
5.69
3.66
1.0
1.3
—
—
—
0
0
9
16
5.69
3.66
3.0
1.7
—
—
—
0
0
44
244
1.87
3.54
1.7
1.6
0.30
0.35
mg/l
0.31
20
113
118
847
1.49
3.51
2.4
2.7
12.13
13.20
umol/l
0.93
111
801
295
2508
1.36
3.27
4.9
3.8
0.00
0.01
estimate
0.50
51
483
146
1107
1.42
3.25
1.9
1.8
1.19
1.38
mg/l
0.40
116
873
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
8
16
5.05
3.05
1.1
1.3
—
—
—
0
0
52
319
1.69
3.01
4.9
3.8
2.13
1.68
mmol/l
0.43
41
245
57
359
1.65
2.99
3.1
1.6
—
—
—
0
0
29
148
2.01
2.99
2.2
1.5
243.40
289.07
ug/g
0.48
15
89
35
193
1.86
2.90
2.1
2.0
—
—
—
0
0
144
1111
1.39
2.87
3.1
2.7
6.65
5.53
e6/l
0.31
133
1014
6
9
6.71
2.87
1.7
1.8
19.28
17.64
umol/l
—
6
9
290
2493
1.32
2.84
4.9
3.8
0.00
3.11
estimate
0.50
56
523
166
2035
0.74
2.71
2.1
2.0
1.59
1.40
mmol/l
1.85
141
1723
286
2467
1.31
2.68
4.9
3.8
0.00
0.00
estimate
-0.00
54
514
16
70
2.32
2.42
1.1
1.0
—
—
—
0
0
195
1613
1.31
2.42
4.1
3.5
239.63
100.26
e6/l
0.31
159
1240
178
2133
0.76
2.41
4.8
5.4
3.03
2.32
ug/l
0.39
140
1923
54
357
1.56
2.37
3.7
4.1
1.23
1.22
mmol/l
0.26
45
318
25
133
1.92
2.34
1.2
1.7
—
—
—
0
0
36
216
1.71
2.30
1.9
1.9
2.80
1.73
ug/l
0.26
29
196
11
40
2.78
2.28
1.0
1.1
—
—
—
0
0
57
386
1.53
2.25
5.0
3.7
5.24
5.13
kpa
0.37
52
374
113
871
1.37
2.25
3.4
3.2
2.45
2.45
mmol/l
0.12
94
789
405
4351
0.77
2.23
7.4
6.7
40.43
39.69
mmol/mol
0.63
370
4093
8
24
3.36
2.18
2.1
2.9
—
—
—
0
0
9
31
2.93
2.07
1.0
1.1
—
—
—
0
0
25
142
1.79
1.95
1.3
1.8
—
—
—
0
0
10
39
2.59
1.94
1.0
1.2
—
—
—
0
0
0
50
0.00
1.89
0.0
1.8
—
—
—
0
0
418
4444
0.78
1.87
5.4
5.2
6.01
6.01
mmol/l
0.03
372
4101
0
54
0.00
1.86
0.0
1.6
—
—
—
0
0
29
175
1.69
1.85
2.2
1.8
—
—
—
0
0
162
1353
1.27
1.81
5.4
3.8
0.00
0.01
estimate
0.96
50
476
476
4969
0.76
1.76
41.4
25.4
132.44
137.06
g/l
7.69
469
4912
18
96
1.90
1.72
2.2
1.3
—
—
—
0
0
18
96
1.90
1.72
2.2
1.3
—
—
—
0
0
5
13
3.86
1.71
1.0
2.9
0.71
0.98
ug/l
—
5
13
5
13
3.86
1.71
1.0
1.5
—
—
—
0
0
476
4966
0.76
1.71
41.8
25.9
39.54
40.81
%
5.45
469
4907
476
4966
0.76
1.71
41.2
25.2
4.39
4.54
e12/l
6.45
465
4860
476
4965
0.76
1.70
41.0
25.1
91.27
91.21
fl
0.09
470
4913
476
4964
0.76
1.68
41.0
25.2
252.89
244.39
e9/l
1.81
466
4870
56
403
1.43
1.68
2.6
2.4
5.27
8.82
ug/l
1.17
47
363
17
90
1.91
1.66
1.2
2.0
—
—
—
0
0
18
98
1.86
1.63
4.2
4.3
5.33
5.11
kpa
0.73
18
98
164
1389
1.25
1.61
4.1
3.4
0.45
0.44
e6/l
0.03
126
1021
13
63
2.09
1.60
1.0
1.7
—
—
—
0
0
24
144
1.69
1.59
1.5
1.6
—
—
—
0
0
6
20
3.02
1.58
1.3
1.1
—
—
—
0
0
368
3398
1.22
1.55
5.1
4.0
14.54
14.79
pmol/l
1.12
333
3112
65
489
1.37
1.53
3.0
2.7
28.16
36.21
u/l
1.20
56
408
50
360
1.42
1.52
2.6
4.5
71.69
91.84
ng/l
2.08
42
327
67
509
1.36
1.49
11.4
6.6
—
—
—
0
0
10
45
2.24
1.46
1.9
1.6
—
—
—
0
0
11
52
2.13
1.45
1.2
2.4
—
—
—
0
0
6
22
2.74
1.43
1.0
1.3
—
—
—
0
0
26
165
1.60
1.42
1.1
1.3
—
—
—
0
0
7
29
2.43
1.39
2.0
2.4
—
—
—
0
0
7
29
2.43
1.39
2.3
1.3
—
—
—
0
0
21
127
1.68
1.38
1.1
1.1
—
—
—
0
0
9
41
2.21
1.37
1.6
1.2
90.67
99.29
pmol/l
—
9
41
419
4408
0.82
1.37
23.6
16.1
86.42
80.92
ml/min/173m2
5.42
387
4096
6
23
2.62
1.37
2.7
2.3
—
—
—
0
0
21
128
1.66
1.34
1.1
1.1
—
—
—
0
0
211
1870
1.20
1.30
4.8
3.7
10.64
0.02
estimate
0.49
47
441
99
811
1.26
1.29
3.7
3.2
3.59
1.49
e6/l
0.85
48
424
76
602
1.30
1.29
3.2
3.1
5.22
9.46
umol/l
2.88
56
549
5
18
2.79
1.28
1.4
1.1
—
—
—
0
0
5
18
2.79
1.28
1.6
2.5
0.62
0.61
mmol/l
—
5
18
21
131
1.62
1.24
3.9
3.4
2.86
1.99
index
0.30
14
82
12
63
1.92
1.23
1.2
1.7
—
—
—
0
0
11
56
1.98
1.22
1.3
2.3
—
—
—
0
0
8
38
2.12
1.18
1.3
1.2
—
—
—
0
0
8
38
2.12
1.18
1.3
1.2
—
—
—
0
0
464
4813
0.81
1.18
14.8
12.7
27.27
28.23
u/l
0.47
447
4690
7
30
2.35
1.12
1.3
1.1
—
—
—
0
0
7
30
2.35
1.12
1.3
1.1
—
—
—
0
0
138
1191
1.21
1.12
3.2
2.5
—
—
—
0
0
49
373
1.34
1.11
2.4
3.4
209.98
230.11
ng/l
0.10
41
338
25
168
1.51
1.11
1.8
1.3
5.74
8.04
u/l
0.75
18
132
22
148
1.50
0.99
1.5
1.3
—
—
—
0
0
0
32
0.00
0.95
0.0
1.3
—
—
—
0
0
36
270
1.35
0.92
1.3
1.2
54.51
131.82
u/ml
—
8
109
32
236
1.38
0.91
2.6
1.8
1.63
1.48
g/l
0.36
27
214
51
406
1.28
0.88
3.1
3.1
66.28
66.36
g/l
0.03
46
379
8
44
1.83
0.86
1.3
1.2
—
—
—
0
0
16
104
1.55
0.85
1.3
1.6
—
—
—
0
0
8
45
1.79
0.84
1.3
1.2
—
—
—
0
0
151
1679
0.86
0.83
3.7
4.3
4.92
9.79
mg/mmol
2.03
89
1082
6
32
1.88
0.82
2.5
3.3
0.67
0.81
index
—
6
32
43
538
0.78
0.81
3.6
4.7
3.66
35.52
ug/l
1.38
32
451
18
122
1.49
0.80
1.4
1.6
—
—
—
0
0
6
33
1.82
0.79
1.0
1.1
—
—
—
0
0
7
123
0.56
0.78
1.9
1.4
—
—
—
0
0
73
616
1.21
0.77
4.0
4.7
236.79
236.06
u/l
0.02
68
587
9
53
1.71
0.75
1.2
1.8
—
—
—
0
0
9
53
1.71
0.75
1.2
1.8
—
—
—
0
0
9
53
1.71
0.75
1.2
1.8
—
—
—
0
0
230
2128
1.13
0.75
3.5
3.1
141.85
147.91
ug/l
0.14
204
1987
26
193
1.36
0.74
2.9
2.9
—
—
—
0
0
15
100
1.51
0.73
1.3
1.3
32.45
38.88
u/l
0.10
15
88
117
1311
0.86
0.71
2.7
2.9
352.04
355.82
umol/l
0.13
93
1157
10
61
1.65
0.68
1.6
1.3
—
—
—
0
0
20
144
1.40
0.68
1.8
1.5
—
—
—
0
0
29
223
1.31
0.67
2.0
1.9
—
—
—
0
0
5
28
1.79
0.66
1.8
1.6
2.08
2.34
ug/l
—
5
23
5
28
1.79
0.66
1.2
1.1
184.20
585.22
u/l
—
5
23
16
111
1.45
0.66
3.4
2.1
131.51
6528.27
u/l
—
7
40
28
215
1.32
0.66
1.2
1.3
—
—
—
0
0
11
70
1.58
0.65
1.1
1.1
0.46
2.62
u/ml
0.95
11
41
18
129
1.41
0.63
1.2
1.1
—
7.81
—
0
14
98
867
1.16
0.62
3.7
3.1
1.54
0.99
e6/l
0.59
46
478
8
49
1.64
0.62
1.1
1.0
—
—
—
0
0
474
4848
0.87
0.61
32.1
21.8
78.97
81.66
umol/l
0.49
469
4795
18
130
1.40
0.61
1.3
1.2
—
2.50
—
0
6
12
80
1.51
0.60
1.7
1.3
7.17
4.63
u/ml
—
6
38
68
780
0.85
0.58
1.3
1.3
1.21
11.84
u/ml
4.20
17
297
56
477
1.19
0.57
2.1
2.0
—
—
—
0
0
24
185
1.31
0.56
1.6
1.9
—
—
—
0
0
15
107
1.41
0.55
1.8
1.9
3.37
4.69
iu/l
—
9
41
6
39
1.54
0.53
2.2
3.5
539.67
821.85
mg
—
6
39
115
1043
1.13
0.52
1.4
1.3
0.76
1.53
u/ml
1.94
29
286
7
48
1.46
0.47
2.1
1.3
—
—
—
0
0
24
191
1.27
0.47
2.9
2.0
4.92
6.35
iu/ml
—
6
48
14
104
1.35
0.43
1.9
1.5
—
—
—
0
0
8
56
1.43
0.42
1.4
1.4
0.29
0.35
nmol/l
—
8
42
50
435
1.16
0.42
2.0
1.9
—
—
—
0
0
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
2.1
—
—
—
0
0
76
840
0.89
0.40
1.4
1.3
26.09
31.59
iu/ml
0.19
20
265
8
60
1.34
0.40
1.0
1.2
—
—
—
0
0
234
2230
1.08
0.39
3.5
2.9
—
—
estimate
—
0
0
71
781
0.90
0.36
1.4
1.5
—
—
—
0
0
287
2764
1.07
0.36
2.8
3.0
—
—
—
0
0
6
44
1.37
0.34
1.2
1.5
110.48
168.42
pmol/l
—
6
44
55
611
0.89
0.33
4.8
4.9
30.03
31.43
%
0.42
36
414
6
46
1.31
0.33
4.3
2.8
—
—
—
0
0
144
1358
1.08
0.31
4.2
3.3
0.00
0.01
estimate
0.99
51
410
18
147
1.23
0.30
2.7
1.4
0.24
0.24
g/l
0.03
18
142
10
75
1.34
0.30
1.3
1.3
—
—
—
0
0
16
130
1.24
0.28
1.2
1.3
—
—
—
0
0
334
3254
1.06
0.27
5.4
3.5
63.79
55.18
u/l
0.78
312
3071
9
72
1.25
0.25
1.3
1.3
—
—
—
0
0
9
72
1.25
0.25
1.3
1.3
—
—
—
0
0
9
73
1.23
0.25
1.3
1.3
—
—
—
0
0
9
73
1.23
0.25
1.3
1.3
—
—
—
0
0
9
75
1.20
0.25
1.3
1.3
—
—
—
0
0
9
75
1.20
0.25
1.0
1.1
—
19.58
—
0
12
9
75
1.20
0.25
1.0
1.1
—
—
—
0
0
5
38
1.32
0.23
1.2
1.2
—
—
—
0
0
5
40
1.25
0.22
1.2
1.2
—
—
—
0
0
5
40
1.25
0.22
1.2
1.2
—
—
—
0
0
473
4668
1.07
0.22
31.9
19.9
139.11
139.68
mmol/l
3.63
465
4583
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
2.2
—
2.37
—
0
6
36
397
0.90
0.21
1.5
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
14
117
1.20
0.20
1.3
1.3
—
—
—
0
0
10
80
1.25
0.20
1.3
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
6
51
1.18
0.19
1.3
1.3
0.20
0.18
nmol/l
—
6
37
350
3434
1.05
0.19
4.4
4.5
14.88
12.00
mm/h
2.27
315
3198
51
473
1.08
0.18
1.5
1.5
—
—
—
0
0
7
58
1.21
0.18
3.3
1.8
9.43
10.58
mmol/l
—
7
58
27
242
1.12
0.18
2.9
3.8
1.02
1.02
ratio
0.21
22
229
162
1564
1.05
0.18
3.6
3.5
1732.87
1424.24
ng/l
0.24
129
1338
7
60
1.17
0.18
1.3
1.3
0.70
0.57
nmol/l
—
7
55
473
4678
1.05
0.17
31.7
20.1
3.98
3.99
mmol/l
0.34
465
4582
5
69
0.72
0.17
1.0
1.2
—
—
—
0
0
8
71
1.13
0.16
1.0
1.2
112.88
112.53
%
—
8
66
13
111
1.17
0.15
1.2
1.8
1.23
0.89
nmol/l
—
7
97
18
159
1.13
0.15
1.5
1.7
—
—
—
0
0
18
159
1.13
0.15
4.1
4.0
1.50
2.24
ratio
—
9
86
10
85
1.18
0.12
1.5
1.7
—
—
—
0
0
15
133
1.13
0.12
4.6
3.2
1.93
1.56
mmol/l
0.98
15
128
17
153
1.11
0.11
2.9
1.5
1.14
1.18
g/l
0.28
17
148
5
46
1.09
0.09
1.2
1.2
—
—
—
0
0
5
48
1.04
0.09
1.2
1.2
—
—
—
0
0
5
48
1.04
0.09
1.4
1.2
—
—
—
0
0
6
56
1.07
0.08
1.0
1.2
97.00
98.71
%
—
6
51
39
406
0.96
0.06
2.6
2.9
68.00
63.54
ml/min/173m2
0.30
15
178
173
1751
0.98
0.06
3.1
3.5
7.54
8.14
mmol/l
0.74
138
1481
12
111
1.08
0.03
5.3
3.4
8.45
7.43
mmol/l
0.44
12
106
14
131
1.07
0.03
1.9
1.7
—
—
—
0
0
456
4543
1.01
0.02
28.5
16.8
29.35
25.21
mg/l
1.64
402
3759
414
4147
0.99
0.02
6.6
5.0
1.92
1.93
mu/l
0.03
378
3820
57
579
0.98
0.02
3.1
2.4
11.81
13.72
nmol/l
1.00
46
524
12
113
1.06
0.01
1.3
1.2
—
—
—
0
0
13
136
0.95
0.01
1.4
1.3
—
—
—
0
0
11
107
1.03
0.00
1.6
1.6
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
16
156
1.03
0.00
3.3
3.0
0.30
0.37
iu/ml
—
7
81
10
96
1.04
0.00
2.1
3.6
4.19
10.11
pmol/l
—
10
96
12
116
1.03
0.00
1.1
1.3
309.40
233.92
u/ml
—
5
63
14
137
1.02
0.00
2.0
2.5
107.47
84.70
ug/min
—
6
77
16
164
0.97
0.00
2.9
2.6
81.06
92.46
%
1.47
16
159
20
205
0.97
0.00
1.1
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
6
69
0.87
-0.00
3.0
2.1
3.33
0.28
mmol/l
—
6
69
6
66
0.91
-0.00
6.7
3.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
0.40
—
0
5
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
94
0.96
-0.00
1.2
1.4
—
—
—
0
0
8
82
0.97
-0.00
1.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
9.1
—
10.89
—
0
7
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
9
96
0.94
-0.00
1.1
3.8
—
2598.70
—
0
10
0
9
0.00
-0.00
0.0
3.2
—
77.60
—
0
9
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
46.57
—
0
7
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint F5_PERSBEHORG and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_PERSBEHORG | 3.369 [2.8, 4.05] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.593 |
During the follow-up period (1.1.1998 — 31.12.2019), 534 out of 1449 females with F5_PERSBEHORG died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_PERSBEHORG | 4.112 [3.58, 4.73] | < 0.001 |
| Birth year | 0.984 [0.98, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 1321 out of 3047 males with F5_PERSBEHORG died.
Mortality risk
Mortality risk for people of age
years, who have F5_PERSBEHORG.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.306% | 0.696% |
| 5 | 2.45% | 4.059% |
| 10 | 5.875% | 10.45% |
| 15 | 10.264% | 18.921% |
| 20 | 17.597% | 30.434% |
Relationships between endpoints
↥Index endpoint: F5_PERSBEHORG – Personality and behavioural disorders due to brain disease, damage and dysfunction
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data