Varicella [chickenpox]

AB1_VARICELLA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 B01
  • Hospital discharge: ICD-9 05[2]
  • Hospital discharge: ICD-8 05[2]
  • Cause of death: ICD-10 B01
  • Cause of death: ICD-9 05[2]
  • Cause of death: ICD-8 05[2]

2 out of 7 registries used, show all original rules.

2111

4. Check minimum number of events

None

2111

5. Include endpoints

None

2111

6. Filter based on genotype QC (FinnGen only)

1894

Control definitions (FinnGen only)

Control exclude
AB1_VIRAL_SKIN_MUCOUS_MEMBRANE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 24317 7662 16552
Only index persons 20463 6106 14357
Unadjusted period prevalence (%)
Whole population 0.38 0.22 0.46
Only index persons 0.45 0.22 0.55
Median age at first event (years)
Whole population 15.07 5.26 19.52
Only index persons 15.83 6.61 19.75

-FinnGen-

Key figures

All Female Male
Number of individuals 1894 622 1272
Unadjusted period prevalence (%) 0.46 0.22 0.58
Median age at first event (years) 17.54 12.06 20.21

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1962
Matched controls
19620
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B01.9
ICD-10 Finland
Varicella without complication
480.0
307.7
527
15
05209
ICD-8 Finland
Chickenpox, Unspecified
+∞
307.7
638
*
0529X
ICD-9 Finland
Chickenpox, Varicella without mention of complication
+∞
273.5
256
*
05200
ICD-8 Finland
Chickenpox, Cum meningoencephalitide
+∞
135.0
128
*
B01.8
ICD-10 Finland
Varicella with other complications
897.6
88.4
86
*
05201
ICD-8 Finland
Chickenpox, Cum complicatione alia
+∞
58.6
56
*
05207
ICD-8 Finland
Chickenpox, Suspectae
+∞
56.5
54
*
J05AB01
ATC
aciclovir; systemic
2.4
51.2
429
2042
L04AA01
ATC
[U] ciclosporin
10.3
49.7
56
56
G05.1*B01.1
ICD-10 Finland
Varicella encephalitis
+∞
45.0
43
*
J05AB11
ATC
valaciclovir; oral
2.5
41.7
291
1265
0528X
ICD-9 Finland
Chickenpox, With unspecified complication
+∞
37.6
36
*
H02AB09
ATC
hydrocortisone; systemic
4.5
33.9
85
197
B01AF, ,
ICD-10 Finland
+∞
33.4
32
*
L04AD01
ATC
ciclosporin; systemic
5.1
33.3
70
140
127
Kela drug reimbursment
Transplant complication
5.0
33.0
71
145
G02.0*B01.0
ICD-10 Finland
Varicella meningitis
+∞
31.3
30
*
0527A
ICD-9 Finland
Chickenpox, With other specified complications
+∞
29.2
28
*
L04AX01
ATC
azathioprine; systemic
3.2
27.8
112
361
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
8.6
25.8
33
39
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
3.4
23.5
88
271
R50.9
ICD-10 Finland
Fever, unspecified
1.9
21.9
322
1847
XW000
NOMESCO Finland
Bone marrow biopsy
3.3
21.9
83
258
L04AA06
ATC
mycophenolic acid; systemic
3.8
20.7
63
169
B03XA01
ATC
erythropoietin; parenteral
7.5
20.4
29
39
602
Kela drug reimbursment
Children's severe malnutrition
6.4
19.3
32
51
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.9
18.8
56
148
A11CC03
ATC
alfacalcidol; systemic
3.7
18.3
58
160
05699
ICD-8 Finland
Rubella, Non definita
+∞
17.7
17
*
Z94.0
ICD-10 Finland
Kidney transplant status
4.4
17.6
44
102
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.6
17.2
102
406
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.0
16.8
47
119
C90.0
ICD-10 Finland
Multiple myeloma
7.4
16.5
24
33
B02.9
ICD-10 Finland
Zoster without complication
2.8
16.0
82
304
ZX120
NOMESCO Finland
Intravenous
2.1
15.9
158
787
H26.2
ICD-10 Finland
Complicated cataract
5.4
15.9
31
58
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.3
15.8
60
187
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.2
15.7
130
602
9835/3-C42.1
ICD-O-3
Precursor cell lymphoblastic leukemia, NOS, of bone marrow
26.5
15.6
21
8
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.1
15.5
161
816
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.6
15.3
50
141
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
15.0
386
2571
J17.1*B01.2
ICD-10 Finland
Varicella pneumonia
+∞
14.6
14
*
B07.9
ICD-10 Finland
Verruca simplex
2.9
14.5
66
229
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
13.5
14.2
24
18
L03AA02
ATC
filgrastim; parenteral
3.2
14.0
55
175
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
13.9
754
5879
L01BA01
ATC
methotrexate; systemic
3.1
13.9
59
197
H02AB04
ATC
methylprednisolone; systemic
1.8
13.8
210
1210
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.5
13.7
89
371
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
13.0
359
2427
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
12.9
246
1512
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
4.9
12.9
28
58
H02AB06
ATC
prednisolone; systemic
1.4
12.8
771
6110
XF602
NOMESCO Finland
Bloodpressure monitoring
4.7
12.6
29
63
BE00A, ,
NOMESCO Finland
70.3
12.6
14
*
WX882
NOMESCO Finland
High dependency care
2.6
12.6
70
271
0520B
ICD-9 Finland
Chickenpox, Postvaricella encephalitis[VARICELLA CUM PNEUMONITIDE]
+∞
12.5
12
*
05697
ICD-8 Finland
Rubella, Suspecta
+∞
12.5
12
*
B01AB, ,
ICD-10 Finland
+∞
12.5
12
*
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
5.3
12.5
25
48
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.3
12.4
95
427
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.9
12.4
159
868
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
12.3
363
2489
ZXD05
NOMESCO Finland
Urgent procedure
1.5
12.0
496
3647
R11
ICD-10 Finland
Nausea and vomiting
1.9
12.0
155
847
Z3231
NOMESCO Finland
Registered nurse
1.5
11.8
467
3406
A04AA01
ATC
ondansetron; systemic, rectal
2.0
11.8
121
611
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
3.3
11.7
44
137
B01.0
ICD-10 Finland
Varicella meningitis
+∞
11.5
11
*
Z3229
NOMESCO Finland
Other healthcare associate professional
1.9
11.3
138
740
A12AA04
ATC
calcium carbonate; oral
3.6
11.3
37
105
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.3
11.1
85
382
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.6
11.0
36
102
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
8.6
11.0
23
27
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
3.5
10.9
36
103
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
10.9
352
2457
B05DB
ATC
Hypertonic solutions
4.8
10.7
24
51
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
10.7
268
1764
Z49.1
ICD-10 Finland
Extracorporeal dialysis
3.7
10.7
33
90
B05DA
ATC
Isotonic solutions
4.4
10.5
26
60
05299, ,
ICD-8 Finland
+∞
10.4
10
*
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
5.5
10.4
20
37
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.6
10.4
60
237
B00.19
ICD-10 Finland
Other vesicular dermatitis caused by the herper simplex virus
16.1
10.3
16
10
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
12.1
10.3
18
15
A41.9
ICD-10 Finland
Sepsis, unspecified
2.7
10.3
56
215
137
Kela drug reimbursment
Uraemia requiring dialysis
4.1
10.2
27
66
A07AA02
ATC
nystatin; oral
2.4
10.0
70
303
46599
ICD-8 Finland
Acute upper respiratory infection of multiple or unspecified sites
1.7
10.0
201
1252
Z85.6
ICD-10 Finland
Personal history of leukaemia
16.8
9.9
15
9
TK800
NOMESCO Finland
Hemodialysis
2.8
9.7
48
175
L04AD02
ATC
tacrolimus; systemic
3.2
9.6
37
117
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.8
9.6
153
894
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
9.6
292
2009
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.9
9.6
122
665
Z2446
NOMESCO Finland
Social worker
1.8
9.4
141
808
C03CA01
ATC
furosemide; systemic
1.5
9.4
281
1924
0520A
ICD-9 Finland
Chickenpox, Postvaricella encephalitis[ENCEPHALITIS POST VARICELLAM]
+∞
9.4
9
*
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
3.1
9.4
37
119
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.1
9.3
92
458
JN6AD
NOMESCO Finland
CT of torso and neck
3.2
9.3
36
114
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
3.8
9.3
28
75
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
4.0
9.3
26
66
S01AD03
ATC
aciclovir; ophthalmic
2.9
9.1
41
142
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.0
9.0
90
450
J01DA01
ATC
[U] cefalexin
1.3
8.8
1008
8680
TAB00
NOMESCO Finland
Lumbar puncture
2.0
8.7
88
443
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
8.6
282
1966
B03XA02
ATC
darbepoetin alfa; parenteral
3.0
8.6
36
120
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
4.8
8.6
19
40
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
2.8
8.6
42
153
ZXE00
NOMESCO Finland
One hour or less
1.4
8.6
604
4835
R06AE07
ATC
cetirizine; oral
1.3
8.6
723
5948
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
2.0
8.6
86
432
A05AA02
ATC
ursodeoxycholic acid; oral
2.9
8.5
38
132
N18.8
ICD-10 Finland
Other chronic renal failure
3.1
8.4
35
116
J02AC01
ATC
fluconazole; systemic
1.4
8.4
494
3840
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
8.4
644
5221
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
1.9
8.3
95
499
B01.1
ICD-10 Finland
Varicella encephalitis
+∞
8.3
8
*
Z3226
NOMESCO Finland
Physiotherapist
1.5
8.3
280
1965
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.7
8.2
158
972
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
6.5
8.2
20
31
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
8.1
306
2196
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
8.0
192
1248
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
8.0
166
1042
J01MA12
ATC
levofloxacin; systemic
1.5
8.0
250
1728
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
7.3
8.0
18
25
N05BA09
ATC
clobazam; oral
3.7
7.9
24
65
WW500
NOMESCO Finland
Blood transfusion
2.2
7.9
61
277
N04.80
ICD-10 Finland
Congenital nephrotic syndrome of the Finnish type
45.2
7.7
9
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.4
7.7
53
229
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
7.6
229
1567
NJ3DA
NOMESCO Finland
Long bones of extremities X-ray examination
8.1
7.6
16
20
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.5
7.6
287
2060
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
7.5
516
4100
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.6
7.5
40
153
J01DA06
ATC
[U] cefuroxime
1.5
7.4
211
1427
M04AA01
ATC
allopurinol; systemic
1.6
7.4
164
1048
L08.0
ICD-10 Finland
Pyoderma
4.0
7.3
20
50
J01DB01
ATC
cefalexin; oral
1.4
7.3
1523
14091
05599
ICD-8 Finland
Measles, Non definita
+∞
7.3
7
*
H19.2*B02.3
ICD-10 Finland
Keratitis and keratoconjunctivitis (interstitial) in zoster
+∞
7.3
7
*
7101
FHL
Needle biopsy in the operating room
+∞
7.3
7
*
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
2.0
7.3
74
374
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
7.3
385
2934
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
3.4
7.3
25
74
ZXD00
NOMESCO Finland
Emergency procedure
2.3
7.2
52
229
A87.9
ICD-10 Finland
Viral meningitis, unspecified
4.3
7.2
18
42
W19
ICD-10 Finland
Unspecified fall
1.6
7.2
163
1048
TPW99
NOMESCO Finland
Other minor surgical procedure on peripheral vessel or lymphatic system
3.5
7.1
24
70
ZXA10
NOMESCO Finland
Bilateral
1.5
7.1
230
1599
K06.18
ICD-10 Finland
Another gingival hyperplasia
6.6
7.1
17
26
Z49.2
ICD-10 Finland
Other dialysis
3.8
7.1
21
56
N05BB01
ATC
hydroxyzine; systemic
1.9
7.1
92
506
ZX121
NOMESCO Finland
Central venous catheter
5.6
7.1
19
34
S18
ICPC
Laceration/cut
1.3
7.0
746
6290
L04AA13
ATC
[U] leflunomide
2.7
7.0
35
129
ZX108
NOMESCO Finland
Inhalation
4.2
7.0
18
43
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
3.2
7.0
27
86
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.7
7.0
120
717
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.6
7.0
177
1168
3AC01, ,
NOMESCO Finland
3.7
6.9
21
57
D70.89
ICD-10 Finland
Neutropenic splenomegaly
3.3
6.8
25
77
B01AB05
ATC
enoxaparin; parenteral
1.4
6.8
398
3077
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
1.7
6.8
117
699
153
Kela drug reimbursment
Lenalidomid
8.3
6.8
14
17
Z94.4
ICD-10 Finland
Liver transplant status
6.1
6.8
17
28
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.8
6.8
98
558
H65.3
ICD-10 Finland
Chronic mucoid otitis media
2.1
6.7
63
309
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
6.7
402
3120
6918B
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[ECZEMA ATOPICUM]
3.4
6.7
23
68
TGC00
NOMESCO Finland
Bronchial lavation
2.5
6.7
41
168
R4110
NOMESCO Finland
Physiotherapy
1.4
6.7
419
3275
JN4AD
NOMESCO Finland
Body CT examination
1.6
6.6
148
948
J01FF01
ATC
clindamycin; systemic
1.4
6.6
422
3308
H26.3
ICD-10 Finland
Drug-induced cataract
5.5
6.6
18
33
N99
ICPC
Neurological disease other
3.6
6.6
21
59
XF600
NOMESCO Finland
Bloodpressure measurement
1.8
6.6
104
608
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
6.9
6.5
15
22
L04AX03
ATC
methotrexate; systemic
1.6
6.5
146
936
A10AB01
ATC
insulin (human); parenteral
2.0
6.5
65
328
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
5.7
6.4
17
30
5639
FHL
Other measure in this category
70.1
6.4
7
*
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
6.4
242
1734
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
6.4
345
2631
A10AA01, ,
ATC
2.2
6.4
52
242
AA1AD
NOMESCO Finland
CT of head and brain
1.4
6.3
369
2850
XX3DW
NOMESCO Finland
Time consuming IT work
1.6
6.3
133
839
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
6.3
403
3156
A02BC02
ATC
pantoprazole; systemic
1.3
6.3
1071
9535
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.0
6.3
69
359
A10AA02, ,
ATC
2.1
6.3
54
257
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.0
6.3
63
318
B01AA, ,
ICD-10 Finland
+∞
6.3
6
*
H22.0*B02.3
ICD-10 Finland
Zoster iridocyclitis
+∞
6.3
6
*
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
6.2
441
3507
7143D
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Juvenile chronic polyarthritis[OLIGARTHRITIS JUVENILIS]
26.8
6.2
8
*
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
2.4
6.2
40
168
E0000UV, ,
ATC
1.3
6.2
659
5538
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
6.2
443
3531
L04AX04
ATC
lenalidomide; oral
7.7
6.1
13
17
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.0
6.1
62
314
TQW99
NOMESCO Finland
Other minor procedure on skin
2.1
6.1
58
287
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
10.0
6.0
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
50
95
5.37
25.19
40.0
27.5
95.67
132.18
ug/l
2.96
44
69
371
2150
1.89
24.69
13.1
7.9
1.07
1.07
mmol/l
0.11
357
2039
26
29
9.07
21.21
2.0
2.1
—
—
—
0
0
575
4005
1.62
19.28
6.0
4.4
—
—
—
0
0
284
1652
1.84
18.28
11.1
5.2
1.24
1.64
mmol/l
1.42
252
1435
250
1397
1.90
18.25
6.6
5.1
0.60
0.95
%
2.46
88
423
241
1333
1.92
18.14
6.5
5.2
0.04
0.11
%
2.07
79
358
288
1691
1.82
17.97
11.0
5.2
5.77
5.84
kpa
0.72
281
1654
844
6493
1.53
17.95
8.0
5.8
36.35
36.80
g/l
1.42
815
6144
291
1724
1.81
17.61
11.1
5.1
7.37
7.38
ph
1.04
191
1021
64
194
3.38
17.57
2.4
2.5
36.34
38.74
%
0.55
64
194
255
1454
1.87
17.45
10.2
4.6
4.69
4.74
kpa
0.14
249
1422
213
1156
1.95
16.92
4.4
3.3
71.19
71.87
e9/l
0.09
163
837
149
710
2.19
16.83
12.5
6.5
1.51
1.32
mg/l
1.59
144
672
97
386
2.59
16.42
1.8
1.9
—
—
—
0
0
73
254
2.95
15.95
4.4
3.4
—
—
—
0
0
236
1353
1.85
15.82
6.2
4.8
0.28
0.66
%
5.13
77
410
53
154
3.51
15.56
1.5
1.8
—
—
—
0
0
262
1563
1.78
15.39
6.3
3.5
1.80
1.74
%
0.35
244
1442
247
1456
1.80
15.09
4.9
2.7
10.12
10.54
g/l
0.63
224
1350
236
1374
1.82
15.02
6.8
5.4
0.20
0.36
%
0.30
70
344
59
188
3.20
14.99
2.4
2.8
1203.37
1243.53
e6/l
0.11
49
162
29
54
5.44
14.96
3.3
2.9
0.57
0.60
mmol/l
1.15
29
54
311
1974
1.68
14.59
2.1
1.7
—
—
—
0
0
899
7209
1.46
14.53
14.2
8.3
1.21
1.21
mmol/l
0.68
795
6353
390
2628
1.60
14.42
7.7
4.6
0.80
0.82
mmol/l
1.34
372
2515
46
129
3.63
14.25
38.7
41.7
6.71
7.52
ug/l
1.44
36
119
1071
8898
1.45
14.21
11.7
7.0
1.91
2.01
e9/l
1.70
986
7919
1046
8677
1.44
13.83
11.7
7.0
0.04
0.04
e9/l
0.24
944
7546
1045
8673
1.44
13.75
11.7
7.0
0.58
0.58
e9/l
0.16
945
7534
364
2441
1.60
13.66
3.3
2.7
29.67
29.50
s
0.22
355
2381
423
2938
1.56
13.65
4.6
2.8
546.08
565.94
mosm/kgh2o
1.01
393
2591
1129
9519
1.44
13.53
15.6
10.1
3.96
4.06
e9/l
0.73
1015
8275
96
417
2.37
13.51
1.7
1.8
66.00
7.32
e6/l
1.79
69
311
61
211
2.95
13.51
2.0
2.0
—
—
—
0
0
977
8034
1.43
13.37
9.9
6.9
12.29
11.89
umol/l
0.31
936
7679
997
8235
1.43
13.28
12.2
7.2
29.04
29.08
%
0.04
954
7894
1072
8974
1.43
13.23
12.3
7.4
0.19
0.20
e9/l
0.33
982
7919
968
7963
1.43
13.13
12.5
7.3
8.91
8.84
%
0.34
923
7559
175
978
1.87
12.66
8.8
4.9
96.40
84.60
ng/l
0.85
165
890
962
7942
1.41
12.58
12.3
7.2
2.91
2.92
%
0.05
916
7533
1116
9458
1.42
12.56
8.8
5.6
6.77
6.68
mmol/l
0.59
1072
8909
244
1508
1.71
12.55
16.8
9.6
9.41
8.22
mmol/l
1.91
239
1459
977
8095
1.41
12.48
11.7
7.0
55.75
55.99
%
0.24
946
7807
960
7930
1.41
12.48
12.5
7.3
0.68
0.69
%
0.30
914
7513
95
426
2.29
12.45
1.8
1.9
1234.03
1144.97
e6/l
0.03
72
334
804
6448
1.42
12.32
14.2
7.9
1.21
1.21
mmol/l
0.25
770
6056
551
4133
1.46
12.10
9.0
4.4
7.39
7.40
ph
0.46
405
2921
123
624
2.04
11.81
5.6
3.9
3.40
3.56
g/l
0.51
117
606
818
6615
1.41
11.79
12.9
10.9
1.17
1.17
inr
0.01
698
5466
842
6846
1.40
11.75
3.4
2.5
71.62
71.98
nmol/l
0.14
789
6399
925
7645
1.40
11.71
17.7
11.0
0.01
0.00
e9/l
0.52
797
6257
26
56
4.69
11.42
1.4
1.2
—
—
—
0
0
366
2553
1.53
11.39
4.7
2.7
13.89
14.34
umol/l
0.53
349
2417
54
196
2.80
11.01
2.7
1.9
—
—
—
0
0
165
946
1.81
10.99
10.1
4.0
129.61
133.73
g/l
1.55
158
930
252
1635
1.62
10.69
1.8
1.6
—
—
—
0
0
709
5665
1.39
10.67
12.2
7.2
—
—
—
0
0
456
3369
1.46
10.63
4.2
2.7
5.12
4.86
e6/l
0.14
427
3070
176
1043
1.76
10.49
5.7
2.6
65.75
67.13
g/l
1.37
166
988
319
2198
1.54
10.43
4.9
2.7
24.15
24.35
%
0.08
304
2093
185
1115
1.73
10.39
1.7
1.4
—
—
—
0
0
53
198
2.72
10.26
2.2
2.4
—
—
—
0
0
187
1135
1.72
10.24
3.3
1.8
1.36
1.31
g/l
0.10
172
1063
347
2450
1.51
10.10
2.0
1.7
—
—
—
0
0
1361
12157
1.39
9.92
12.1
7.9
82.81
79.21
u/l
1.57
1321
11645
58
231
2.56
9.90
6.3
4.0
0.69
1.44
%
2.60
51
216
194
1200
1.68
9.90
5.8
4.4
7.41
7.41
ph
0.40
161
992
45
159
2.87
9.67
1.5
1.4
—
—
—
0
0
30
83
3.66
9.55
2.5
2.6
0.15
0.25
e9/l
1.10
17
48
556
4330
1.40
9.52
5.4
3.2
0.30
0.40
e6/l
0.60
443
3106
623
4961
1.37
9.28
3.8
2.5
—
—
—
0
0
70
314
2.27
9.24
4.0
3.6
3.69
4.00
e9/l
0.69
70
314
170
1034
1.71
9.23
7.9
4.3
1.22
1.23
mmol/l
1.16
156
905
195
1230
1.65
9.23
5.8
4.3
5.07
5.12
kpa
0.53
187
1189
232
1529
1.59
9.18
18.3
12.2
—
—
—
0
0
43
153
2.85
9.14
2.3
3.0
198.61
222.57
e6/l
0.26
33
127
71
327
2.22
8.81
1.3
1.2
—
—
—
0
0
625
5014
1.36
8.78
5.5
3.3
36.31
89.55
e6/l
1.29
512
3784
231
1537
1.57
8.77
3.2
2.8
0.22
0.22
g/l
0.03
213
1450
37
124
3.02
8.75
2.8
2.9
33.02
41.48
%
1.62
12
58
332
2398
1.46
8.53
4.8
2.6
2.34
2.38
g/l
0.56
315
2252
541
4259
1.37
8.52
7.5
4.6
90.62
90.91
%
0.11
530
4181
41
148
2.81
8.51
2.3
3.0
580.48
568.98
e6/l
0.03
31
118
184
1174
1.63
8.32
2.4
2.4
8.96
17.67
au/ml
4.51
23
151
503
3930
1.38
8.26
2.1
1.5
2.21
2.38
g/l
0.99
334
2540
54
230
2.39
8.05
3.1
1.5
—
—
—
0
0
172
1088
1.64
8.05
1.3
1.3
29.91
51.79
au/ml
—
10
75
520
4103
1.36
7.99
7.6
4.7
—
—
—
0
0
133
788
1.74
7.96
5.9
2.1
—
—
—
0
0
86
444
1.98
7.94
2.1
1.6
104.76
141.79
au/ml
1.65
23
149
556
4438
1.35
7.92
4.4
2.7
353.56
350.68
umol/l
0.28
515
4087
18
39
4.65
7.88
1.8
1.7
—
—
—
0
0
317
2303
1.45
7.87
2.4
2.2
—
—
—
0
0
688
5680
1.33
7.76
4.6
3.6
8.64
8.93
mmol/l
0.76
602
4993
89
469
1.94
7.76
2.0
1.6
—
—
—
0
0
144
884
1.68
7.58
1.9
1.6
5.33
6.52
u/l
1.38
120
681
105
590
1.82
7.52
2.9
2.0
1.38
1.40
g/l
0.07
96
516
613
4999
1.33
7.48
3.2
2.8
58.69
61.12
u/l
0.53
580
4714
485
3827
1.36
7.37
2.8
2.3
2.86
2.65
mg/l
1.22
437
3371
604
4928
1.33
7.31
5.2
4.3
11.69
9.47
mg/mmol
0.56
416
3360
700
5835
1.31
7.25
6.4
3.9
57.17
64.44
e6/l
0.16
543
4052
106
606
1.79
7.19
5.0
2.6
1.02
1.02
ratio
0.60
99
554
680
5660
1.31
7.08
4.2
3.2
55.20
54.41
ng/l
0.02
491
3525
31
107
2.93
7.02
4.1
3.5
1151.29
656.61
u/ml
1.04
31
107
236
1658
1.48
6.93
2.8
2.4
356.36
369.64
nmol/l
0.55
228
1567
176
1167
1.56
6.78
3.1
2.4
0.34
0.26
e6/l
0.32
165
1117
141
894
1.62
6.57
5.9
4.7
—
—
—
0
0
574
4719
1.31
6.42
3.8
3.5
2.35
2.35
mmol/l
0.52
539
4388
260
1889
1.43
6.40
1.8
1.7
1100.96
1119.09
nmol/l
0.12
218
1491
30
108
2.81
6.32
5.3
2.0
—
—
—
0
0
22
66
3.36
6.28
2.6
1.9
30.45
29.77
%
0.07
22
66
50
231
2.19
6.25
1.9
1.7
—
—
—
0
0
50
231
2.19
6.25
1.9
1.7
—
—
—
0
0
50
231
2.19
6.25
1.9
1.7
—
—
—
0
0
50
231
2.19
6.25
1.9
1.7
—
—
—
0
0
72
384
1.91
6.12
10.5
3.2
71.12
32.87
mg/l
0.77
61
318
72
384
1.91
6.12
10.5
3.2
57.77
64.24
mg/l
0.11
61
319
717
6097
1.28
6.12
4.9
3.6
46.27
37.45
u/l
0.26
681
5773
62
316
1.99
6.01
4.9
4.7
2.00
2.43
mmol/l
1.00
42
200
351
2714
1.36
5.96
4.7
2.9
1.12
0.82
e6/l
0.40
209
1366
91
527
1.76
5.96
2.3
1.5
0.23
0.24
g/l
0.70
84
502
41
178
2.33
5.94
3.4
2.6
1.76
2.02
g/24h
0.11
25
115
330
2533
1.36
5.87
4.8
3.0
2.65
1.65
e6/l
0.86
182
1185
902
7913
1.26
5.85
4.4
3.1
157.12
127.99
ug/l
0.96
858
7564
583
4855
1.29
5.81
4.4
3.6
68.22
57.41
mg/l
0.42
403
3370
559
4631
1.29
5.80
2.6
2.3
212.54
254.68
u/l
0.43
540
4438
96
572
1.71
5.70
6.0
4.6
203.37
365.20
mg/l
1.21
63
330
973
8632
1.25
5.65
4.7
3.3
5.90
5.50
estimate
0.02
239
1731
106
652
1.66
5.60
2.4
1.7
6.66
5.94
iu/ml
0.09
27
157
90
530
1.73
5.58
2.3
2.1
2.08
1.46
ug/l
0.37
81
488
456
3697
1.30
5.55
4.5
3.2
1411.42
1005.85
ng/l
0.71
382
3027
77
435
1.80
5.50
4.6
3.3
57.51
56.61
%
0.26
77
435
1752
16770
1.42
5.36
23.7
15.4
3.98
3.97
mmol/l
0.20
1734
16430
316
2444
1.35
5.33
1.5
1.4
519.34
456.68
titre
0.20
61
446
136
900
1.55
5.33
1.4
1.2
—
—
—
0
0
19
58
3.30
5.31
1.2
1.2
—
—
—
0
0
466
3809
1.29
5.30
3.7
2.5
—
—
—
0
0
588
4951
1.27
5.27
10.0
6.4
—
—
—
0
0
166
1150
1.48
5.25
1.2
1.3
156.31
138.42
u/ml
0.27
64
426
88
527
1.70
5.16
1.5
1.3
—
—
—
0
0
70
393
1.81
5.13
3.7
2.9
2.32
2.04
index
0.20
41
228
412
3328
1.30
5.11
2.0
1.7
—
—
—
0
0
971
8675
1.24
5.08
4.7
3.3
0.05
0.20
estimate
0.39
228
1603
959
8559
1.24
5.06
4.7
3.3
0.00
0.00
estimate
0.50
238
1735
17
50
3.42
5.03
3.8
1.8
—
—
—
0
0
65
359
1.84
5.02
5.4
3.7
—
—
—
0
0
86
516
1.70
5.02
1.7
1.4
314.21
231.41
u/ml
1.14
53
297
29
117
2.50
4.96
1.9
1.7
—
—
—
0
0
47
236
2.02
4.81
6.0
6.9
10.50
10.70
mg/l
0.10
39
221
64
357
1.82
4.81
1.2
1.7
0.91
0.85
g/l
0.08
48
282
28
113
2.50
4.80
4.5
2.7
1050.96
1318.76
mg
0.40
28
113
661
5698
1.24
4.73
2.1
1.9
—
—
—
0
0
1741
16705
1.37
4.71
23.3
15.3
139.64
139.66
mmol/l
0.10
1724
16401
115
756
1.55
4.67
4.6
3.1
21.02
21.01
s
0.00
104
683
837
7411
1.23
4.62
3.8
2.8
—
—
estimate
—
0
0
452
3740
1.27
4.60
2.6
2.0
1.33
1.08
mg/l
0.43
363
2848
1175
10774
1.23
4.58
5.9
4.0
—
3.28
—
0
20
36
167
2.18
4.54
1.7
2.2
1.00
0.94
%
0.21
26
104
501
4205
1.26
4.51
2.3
2.1
—
—
—
0
0
709
6192
1.23
4.42
2.2
1.9
95.29
95.63
pmol/l
0.07
431
3529
310
2456
1.31
4.41
3.1
3.0
159.20
127.02
ug/g
0.61
262
2033
33
151
2.21
4.31
4.0
3.9
56.68
56.97
%
0.02
28
139
255
1971
1.34
4.31
6.2
3.2
9.01
7.93
umol/l
0.30
222
1729
348
2811
1.29
4.27
2.6
2.4
13.78
14.10
nmol/l
0.36
331
2635
788
6980
1.22
4.22
4.2
3.0
6.17
6.12
ph
0.73
466
4075
94
605
1.58
4.21
2.2
2.2
—
—
—
0
0
33
153
2.18
4.19
6.6
4.7
—
—
—
0
0
27
115
2.37
4.16
1.1
1.3
—
—
—
0
0
23
91
2.55
4.13
3.2
1.5
18.55
8.29
ug/l
0.34
23
83
90
576
1.59
4.13
1.3
1.1
—
—
—
0
0
526
4479
1.24
4.12
4.5
3.4
0.01
0.01
estimate
0.13
217
1606
60
346
1.76
4.08
11.2
3.0
4.89
2.08
ratio
0.36
36
195
55
309
1.80
4.08
3.7
2.5
17.13
17.09
%
0.03
55
301
92
595
1.57
4.05
5.2
6.4
0.92
0.86
%
0.90
87
554
93
603
1.57
4.05
1.2
1.2
—
—
—
0
0
211
1601
1.36
4.03
3.0
2.7
35.87
70.84
u/l
0.63
192
1390
11
22
5.02
4.00
1.5
2.2
—
—
—
0
0
34
163
2.11
3.98
2.8
3.3
—
—
—
0
0
77
480
1.63
3.95
3.1
2.4
11.02
11.11
mg/l
0.03
71
455
38
191
2.01
3.94
2.2
2.3
—
—
—
0
0
14
43
3.27
3.91
1.0
1.4
—
—
—
0
0
1333
12473
1.21
3.87
4.4
3.8
14.66
14.54
pmol/l
1.05
1264
11659
1739
16767
1.33
3.84
21.7
13.5
22.14
23.45
mg/l
1.01
1485
13487
439
3699
1.24
3.75
1.9
1.6
18.39
19.66
nmol/l
1.12
391
3251
23
96
2.41
3.73
1.7
1.8
—
—
—
0
0
1064
9777
1.19
3.65
5.4
3.9
3916.64
721.77
e6/l
0.37
11
108
159
1172
1.39
3.65
3.9
4.8
15.14
30.80
ug/l
0.74
132
947
23
97
2.39
3.65
5.9
4.6
—
—
—
0
0
126
893
1.44
3.61
1.8
1.6
12.71
19.71
iu/l
2.46
99
714
19
74
2.58
3.55
1.2
1.1
98.20
186.00
ng/l
—
10
22
123
871
1.44
3.55
1.7
1.4
—
—
—
0
0
48
271
1.79
3.55
2.3
2.4
15.87
27.01
iu/ml
—
7
25
14
46
3.06
3.53
1.0
1.0
—
—
—
0
0
24
106
2.28
3.46
4.5
5.1
8.55
9.25
mg/l
0.26
19
94
46
259
1.79
3.44
1.2
1.2
—
—
—
0
0
1366
12873
1.20
3.42
4.5
3.5
50.40
48.64
u/l
0.32
1316
12391
37
195
1.91
3.39
2.2
3.3
—
—
—
0
0
334
2771
1.25
3.26
1.7
1.7
30208766.79
35507062.28
pmol/l
0.06
288
2408
181
1388
1.33
3.26
2.2
2.0
0.04
0.01
estimate
0.27
53
368
20
84
2.40
3.23
1.1
1.1
—
—
—
0
0
73
475
1.56
3.19
1.4
1.4
264.56
275.63
ug/g
0.17
36
279
20
85
2.37
3.15
1.1
1.0
—
—
—
0
0
96
665
1.47
3.14
5.2
6.0
1.52
1.73
%
1.16
91
622
10
25
4.02
3.08
6.7
7.7
4.71
7.52
mmol/l
—
10
25
28
140
2.01
3.01
1.5
1.2
—
—
—
0
0
253
2052
1.27
3.00
1.8
1.6
—
—
—
0
0
44
257
1.73
2.95
3.5
2.8
10.11
7.59
umol/l
0.51
35
198
166
1281
1.32
2.88
1.6
1.3
389.34
260.74
u/ml
0.50
154
1198
12
38
3.17
2.85
1.5
1.4
13.23
17.39
pmol/l
—
6
17
20
90
2.23
2.80
3.4
3.7
189.42
144.53
umol/l
0.28
12
47
565
5005
1.18
2.78
4.0
2.7
0.03
0.07
estimate
0.50
196
1398
9
23
3.93
2.77
4.9
5.2
—
—
—
0
0
1828
17864
1.34
2.75
15.9
10.9
30.19
30.18
u/l
0.01
1795
17510
161
1246
1.32
2.75
4.4
3.7
—
—
—
0
0
96
684
1.42
2.74
5.6
4.8
37.00
36.94
°c
0.95
96
678
9
24
3.76
2.67
2.1
2.0
—
—
—
0
0
34
190
1.80
2.67
1.4
1.3
—
—
—
0
0
731
6631
1.16
2.65
4.4
3.1
0.01
0.02
estimate
0.02
202
1467
12
41
2.94
2.62
2.2
2.2
—
—
—
0
0
47
290
1.64
2.61
1.8
1.5
0.55
0.32
nmol/l
0.63
38
228
257
2125
1.24
2.60
3.5
3.4
4.21
5.01
e9/l
1.35
228
1919
212
1715
1.26
2.59
12.7
11.0
7.42
7.41
ph
0.40
98
930
19
87
2.20
2.57
1.2
1.3
—
—
—
0
0
194
1556
1.27
2.55
13.0
11.4
95.48
95.91
%
0.44
189
1501
558
4971
1.17
2.53
3.8
2.5
0.07
0.03
0.21
14
62
14
56
2.51
2.53
1.8
1.3
—
—
—
0
0
7
16
4.39
2.47
6.9
4.8
—
—
—
0
0
211
1718
1.26
2.45
12.6
10.9
5.01
5.14
kpa
1.14
202
1655
211
1718
1.26
2.45
12.6
10.9
12.12
12.68
kpa
0.79
201
1658
209
1700
1.26
2.45
12.8
10.9
0.25
0.77
mmol/l
0.91
165
1430
145
1127
1.31
2.43
4.8
4.2
7.37
7.34
ph
3.03
121
846
5
8
6.26
2.37
1.0
1.1
—
—
—
0
0
25
133
1.89
2.31
1.2
1.3
0.62
0.57
ratio
0.44
14
76
53
349
1.53
2.28
3.3
2.3
130.05
135.55
g/l
0.84
44
277
11
40
2.76
2.27
2.5
3.3
—
—
—
0
0
36
216
1.68
2.26
1.3
1.3
—
—
—
0
0
14
60
2.34
2.22
3.7
2.4
39.36
92.81
ug/l
2.96
14
60
122
939
1.32
2.22
3.6
3.0
198.92
136.53
ng/l
1.01
108
838
78
559
1.41
2.21
1.9
1.8
—
—
—
0
0
78
560
1.41
2.19
1.4
1.3
73.64
130.00
titre
0.96
11
63
7
19
3.69
2.15
7.7
3.9
—
—
—
0
0
36
220
1.65
2.13
1.2
1.3
6.62
6.47
g/l
0.09
23
159
36
220
1.65
2.13
1.2
1.3
2.59
2.83
g/l
0.32
24
157
36
220
1.65
2.13
1.2
1.3
0.34
0.37
g/l
0.14
23
156
23
123
1.88
2.11
1.0
1.0
—
—
—
0
0
65
456
1.44
2.09
1.4
1.2
8.40
2.92
u/ml
—
5
39
1561
15089
1.17
2.08
5.2
4.5
1.84
1.82
mu/l
0.37
1492
14244
115
888
1.31
2.06
1.9
1.7
314.77
297.25
mu/l
0.26
108
824
486
4348
1.16
2.05
1.5
1.4
1.43
2.45
u/ml
1.47
130
1205
52
351
1.49
2.03
1.1
1.1
—
—
—
0
0
234
2763
0.83
2.03
2.2
2.0
3.78
3.70
ratio
0.32
185
2155
285
2445
1.19
2.01
2.6
3.0
2.43
2.43
mmol/l
0.14
261
2183
72
519
1.40
2.00
3.5
4.0
821.02
2941.29
u/ml
0.55
61
461
10
38
2.64
2.00
1.1
1.3
—
—
—
0
0
19
97
1.97
2.00
1.3
1.2
—
—
—
0
0
18
91
1.99
1.95
1.2
1.2
—
—
—
0
0
245
2082
1.20
1.93
1.3
1.3
—
—
—
0
0
41
268
1.54
1.87
1.9
1.6
368.03
330.71
mu/l
0.50
35
217
102
787
1.31
1.86
2.4
2.2
0.03
0.86
estimate
0.49
31
295
23
129
1.79
1.85
1.4
1.2
—
—
—
0
0
81
608
1.35
1.79
1.3
1.3
—
—
—
0
0
124
988
1.27
1.79
2.0
2.0
213.62
209.61
pmol/l
0.16
119
944
49
339
1.46
1.73
1.1
1.1
—
—
—
0
0
78
586
1.34
1.73
2.0
1.9
—
—
—
0
0
19
103
1.85
1.71
1.4
1.2
—
46.70
—
0
6
5
13
3.85
1.71
4.8
2.8
25.20
28.62
umol/l
—
5
13
28
171
1.65
1.70
1.6
2.2
31.96
32.87
pg
0.43
28
171
20
111
1.81
1.68
1.2
1.1
1657.75
1490.81
miu/ml
0.21
20
111
222
2587
0.84
1.68
1.5
1.4
—
—
—
0
0
24
141
1.71
1.68
1.5
1.2
—
—
—
0
0
24
141
1.71
1.68
1.3
1.7
11.71
12.27
umol/l
0.21
24
131
26
157
1.66
1.66
1.0
1.2
0.32
1.80
u/ml
0.98
11
65
23
135
1.71
1.62
3.4
2.8
0.89
0.87
nmol/l
0.07
16
110
5
14
3.58
1.61
4.8
2.6
38.20
34.57
umol/l
—
5
14
53
380
1.41
1.58
1.2
1.1
21.13
13.64
au/ml
—
10
109
34
223
1.53
1.57
15.8
4.6
11.78
11.64
%
0.08
34
223
1821
17927
1.22
1.49
25.2
16.4
80.85
77.12
umol/l
3.23
1808
17767
270
2372
1.16
1.47
2.0
1.9
—
—
—
0
0
43
302
1.43
1.45
3.1
3.4
24.74
27.96
mg/l
0.27
27
200
15
80
1.88
1.44
1.1
1.1
0.58
2.28
u/ml
—
6
53
11
52
2.12
1.44
1.6
1.4
85.27
98.31
nmol/24h
0.26
11
52
14
73
1.92
1.44
1.1
1.2
27.07
28.22
s
0.39
14
73
13
66
1.98
1.43
2.5
2.5
1.88
1.75
mmol/l
—
8
53
30
196
1.54
1.43
2.6
1.8
—
—
—
0
0
48
346
1.40
1.41
1.2
1.2
4.50
4.52
u/ml
0.00
22
165
7
29
2.42
1.39
1.3
2.3
—
—
—
0
0
37
255
1.46
1.38
2.1
2.2
—
—
—
0
0
20
119
1.69
1.37
2.0
1.5
39.62
29.43
%
0.57
14
82
5
17
2.95
1.36
1.4
1.2
—
—
—
0
0
22
135
1.64
1.36
3.0
2.7
—
—
—
0
0
25
159
1.58
1.34
1.0
1.1
0.83
4.47
u/ml
—
9
56
20
121
1.66
1.30
1.3
1.2
101.05
108.88
pmol/l
0.25
20
121
68
528
1.30
1.27
2.6
2.8
—
—
—
0
0
113
934
1.22
1.25
3.8
3.5
4.59
4.70
pmol/l
0.66
106
856
5
19
2.64
1.21
1.0
1.2
139.00
137.17
mmol/l
—
5
12
5
19
2.64
1.21
6.8
9.1
8.16
8.79
mmol/l
—
5
19
5
19
2.64
1.21
2.8
3.8
—
—
—
0
0
24
156
1.55
1.20
2.3
1.7
52.22
55.88
%
0.17
18
113
62
480
1.30
1.19
1.7
2.1
1.02
0.84
nmol/l
0.61
54
416
1581
15454
1.12
1.19
6.7
5.6
39.40
38.75
mmol/mol
1.89
1514
14866
327
2960
1.13
1.17
1.3
1.3
32.64
27.45
iu/ml
0.29
96
885
17
102
1.67
1.16
2.1
4.3
0.52
1.63
ug/l
3.82
17
97
82
1009
0.80
1.15
1.4
1.6
—
—
—
0
0
21
134
1.57
1.14
2.4
2.0
—
—
—
0
0
187
1633
1.16
1.14
4.7
4.2
30.52
30.21
%
0.17
147
1186
7
30
2.34
1.12
1.0
1.2
—
—
—
0
0
20
127
1.58
1.11
1.2
1.1
—
—
—
0
0
208
1835
1.15
1.11
1.3
1.2
—
—
—
0
0
30
209
1.44
1.10
1.1
1.1
—
—
—
0
0
36
261
1.39
1.08
2.2
1.7
—
—
—
0
0
101
842
1.21
1.06
2.3
2.4
11283.76
5615.92
u/l
0.59
38
312
10
52
1.93
1.06
1.8
1.3
—
—
—
0
0
7
33
2.13
1.05
1.4
1.3
—
—
—
0
0
7
33
2.13
1.05
1.4
1.1
—
—
—
0
0
37
272
1.37
1.03
1.6
1.4
167.88
204.52
pmol/l
0.47
37
272
53
412
1.29
1.02
1.4
1.3
—
—
—
0
0
9
47
1.92
1.02
1.9
2.2
41.61
41.83
g/l
—
9
47
578
5428
1.09
1.02
1.6
1.5
—
—
—
0
0
49
379
1.30
0.99
2.3
1.6
18900.26
11466.57
e6/l
0.48
43
280
139
1202
1.17
0.98
2.5
2.0
5.99
6.07
ph
0.45
87
750
55
433
1.28
0.97
1.2
1.2
—
—
—
0
0
21
140
1.51
0.97
2.2
1.4
26941.38
98758.52
e6/l
0.69
16
99
18
116
1.56
0.96
1.0
1.0
—
—
—
0
0
1593
15630
1.10
0.94
4.9
4.4
5.97
5.91
mmol/l
0.82
1517
14750
14
85
1.65
0.94
1.3
1.3
137.93
147.85
nmol/l
0.34
14
85
11
62
1.78
0.94
3.9
2.5
120.55
117.85
ng/l
0.03
11
62
6
27
2.23
0.93
1.2
1.1
—
—
—
0
0
65
528
1.24
0.90
1.1
1.1
4.52
6.16
u/ml
0.45
34
313
104
887
1.18
0.89
7.2
8.2
23.75
24.54
mmol/l
1.37
98
844
172
1525
1.14
0.89
1.2
1.2
—
—
—
0
0
12
71
1.69
0.88
1.7
2.0
—
34.27
—
0
9
185
2070
0.88
0.88
1.9
1.7
3.42
3.47
mmol/l
0.26
135
1450
294
2698
1.11
0.85
1.3
1.3
11.14
9.96
u/ml
0.10
118
1112
20
137
1.46
0.84
1.3
1.1
—
—
—
0
0
20
137
1.46
0.84
1.1
1.1
0.18
6.02
u/ml
—
7
42
77
643
1.21
0.84
1.5
1.7
12.30
12.11
u/ml
0.01
20
173
41
318
1.30
0.84
1.2
1.2
—
—
—
0
0
55
443
1.25
0.84
2.2
2.0
3.07
4.19
iu/l
0.79
19
191
1507
14776
1.09
0.83
25.5
16.6
13.55
13.40
%
4.78
1494
14607
17
113
1.51
0.82
1.4
1.1
—
—
—
0
0
408
3816
1.09
0.79
3.9
3.2
1.02
1.43
kg/l
0.50
258
2474
71
593
1.20
0.78
1.1
1.2
4.30
3.19
u/ml
0.22
41
344
12
187
0.64
0.78
12.4
22.4
1328.67
1378.39
nmol/l
0.08
12
181
13
82
1.59
0.78
1.3
1.2
—
—
—
0
0
32
245
1.31
0.74
1.6
1.4
69.92
70.51
mmol/l
0.02
25
209
26
193
1.35
0.73
1.3
1.2
—
61.74
—
0
9
5
25
2.00
0.72
1.0
1.1
—
—
—
0
0
5
25
2.00
0.72
1.4
1.3
—
—
—
0
0
5
25
2.00
0.72
1.0
1.0
—
—
—
0
0
9
56
1.61
0.72
1.1
1.1
—
—
—
0
0
9
56
1.61
0.72
1.1
1.1
—
—
—
0
0
9
56
1.61
0.72
1.1
1.1
—
—
—
0
0
59
492
1.21
0.68
1.1
1.1
4.94
8.00
eliau/ml
0.41
11
88
10
61
1.64
0.68
7.5
3.9
17.03
86.27
u/ml
—
10
61
97
845
1.16
0.68
4.9
5.8
—
—
—
0
0
9
59
1.53
0.68
1.1
1.2
—
—
—
0
0
26
197
1.32
0.66
1.5
1.3
—
—
—
0
0
38
304
1.25
0.65
1.1
1.1
1.83
3.22
eliau/ml
0.73
17
145
142
1277
1.12
0.63
2.0
2.0
—
—
—
0
0
13
87
1.50
0.63
1.6
1.5
0.68
0.49
e9/l
1.40
13
87
120
1069
1.13
0.63
1.2
1.2
—
—
—
0
0
97
853
1.14
0.62
2.6
2.8
—
—
—
0
0
46
379
1.22
0.62
1.1
1.1
73.59
112.10
iu/ml
—
7
93
142
1284
1.11
0.59
2.0
2.0
—
—
—
0
0
11
72
1.53
0.59
2.4
1.4
—
—
—
0
0
203
1870
1.10
0.59
1.5
1.4
—
—
—
0
0
27
210
1.29
0.58
1.9
1.4
286.80
286.78
mosm/kgh2o
0.00
20
161
114
1018
1.13
0.58
1.2
1.2
127.50
148.12
titre
—
6
34
8
53
1.51
0.58
1.8
2.5
—
—
—
0
0
113
1010
1.13
0.57
2.0
2.1
—
—
—
0
0
1519
15405
0.94
0.56
24.7
16.5
334.63
334.84
g/l
0.40
1513
15325
89
1007
0.88
0.56
1.1
1.1
0.71
0.69
ratio
0.09
11
97
23
176
1.31
0.56
1.1
1.1
—
—
—
0
0
142
1289
1.11
0.56
2.0
2.0
—
—
—
0
0
81
711
1.15
0.55
1.3
1.3
201.31
226.73
miu/ml
0.24
32
325
60
515
1.17
0.54
1.1
1.1
1.03
1.20
u/ml
0.15
29
263
6
38
1.58
0.54
3.2
2.6
—
—
—
0
0
140
1273
1.11
0.54
2.0
2.0
—
—
—
0
0
59
508
1.17
0.52
1.1
1.1
3.50
2.21
u/ml
0.30
33
288
132
1200
1.11
0.51
2.0
2.1
—
—
—
0
0
11
75
1.47
0.50
1.3
1.7
0.91
3.07
u/field
0.54
11
62
1596
15769
1.06
0.50
4.6
4.1
1.39
1.38
mmol/l
0.25
1523
15036
124
1132
1.10
0.46
1.7
1.9
0.38
0.32
mg/l
0.60
63
616
7
49
1.43
0.46
1.9
2.6
—
—
—
0
0
741
7196
1.05
0.45
2.0
1.9
1.41
1.48
mmol/l
1.30
638
6316
63
715
0.88
0.45
1.7
1.6
—
—
—
0
0
66
583
1.14
0.43
1.1
1.1
—
—
—
0
0
202
2155
0.93
0.43
1.8
1.5
—
—
—
0
0
45
387
1.17
0.42
1.1
1.1
7.50
7.46
u/ml
0.00
20
192
5
32
1.56
0.42
2.2
1.4
—
—
—
0
0
13
98
1.33
0.37
1.8
1.4
—
—
—
0
0
5
37
1.35
0.37
3.2
3.4
6.00
4.35
ug/l
—
5
37
17
134
1.27
0.37
1.6
1.5
85.94
77.75
umol/l
0.42
17
134
23
189
1.22
0.36
1.2
1.2
13.61
16.62
u/ml
0.30
12
83
23
189
1.22
0.36
1.3
1.2
290.00
160.57
titre
—
5
35
37
320
1.16
0.34
1.2
1.2
—
—
—
0
0
10
73
1.37
0.34
1.2
1.1
—
10.41
—
0
16
12
91
1.32
0.33
1.1
1.1
—
13.20
—
0
5
17
136
1.25
0.33
1.2
1.5
1.83
3.45
u/ml
—
9
79
6
46
1.31
0.33
1.2
1.1
—
—
—
0
0
1883
18756
1.10
0.33
30.5
20.2
90.43
90.21
fl
1.23
1875
18618
25
210
1.19
0.32
2.2
1.4
1.89
1.41
promille
0.53
17
167
1883
18757
1.10
0.32
30.5
20.2
30.31
30.28
pg
0.35
1875
18619
14
110
1.27
0.31
1.4
1.4
—
—
—
0
0
1882
18748
1.09
0.31
30.6
20.3
250.37
250.17
e9/l
0.05
1862
18438
1883
18759
1.09
0.31
31.9
20.9
41.25
42.39
%
2.21
1875
18609
1883
18759
1.09
0.31
30.6
20.3
4.62
4.67
e12/l
3.68
1857
18415
461
4751
0.96
0.30
2.8
2.7
0.69
0.68
ug/l
0.11
237
2544
42
473
0.89
0.30
1.1
1.1
—
—
—
0
0
11
84
1.31
0.30
1.8
1.7
—
—
—
0
0
1883
18763
1.09
0.29
30.6
20.3
7.07
6.69
e9/l
0.71
1857
18410
1883
18764
1.09
0.28
30.9
20.4
139.07
140.66
g/l
4.26
1875
18626
53
479
1.11
0.28
7.8
8.8
—
—
—
0
0
8
65
1.23
0.27
1.7
2.5
21.77
16.68
umol/l
—
8
65
124
1172
1.06
0.24
2.4
2.3
12.67
10.18
ug/l
0.29
115
1069
9
76
1.19
0.24
1.4
1.1
—
—
—
0
0
43
475
0.90
0.24
1.1
1.1
—
—
—
0
0
772
7589
1.03
0.24
4.2
4.1
1.73
1.81
ug/l
0.23
719
7075
1682
16725
1.04
0.23
5.7
5.2
2.75
2.79
mmol/l
1.18
1616
16043
5
38
1.32
0.23
1.0
1.4
—
—
—
0
0
5
38
1.32
0.23
1.0
1.4
—
—
—
0
0
5
38
1.32
0.23
1.0
1.4
—
—
—
0
0
10
79
1.27
0.22
1.6
1.5
0.00
0.08
estimate
—
10
79
0
11
0.00
0.21
0.0
4.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
0.15
—
0
11
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
219.50
—
0
12
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
11
89
1.24
0.21
1.0
1.1
102.38
210.18
iu/ml
2.08
11
89
306
2973
1.03
0.20
4.5
3.7
948.64
675.58
ng/l
0.32
227
2126
35
316
1.11
0.20
1.1
1.1
—
—
—
0
0
14
117
1.20
0.20
2.4
2.3
675.78
616.83
ml
—
9
80
0
14
0.00
0.20
0.0
1.0
—
35.17
—
0
6
118
1238
0.95
0.19
1.1
1.1
—
—
—
0
0
46
423
1.09
0.19
1.1
1.1
9.88
4.79
u/ml
0.57
22
227
795
8057
0.98
0.18
3.4
2.9
—
—
—
0
0
24
217
1.11
0.14
1.3
1.4
0.51
0.59
nmol/l
0.62
24
207
11
93
1.18
0.14
4.5
2.7
1760.82
2152.37
ml
0.49
11
88
33
357
0.92
0.14
2.8
2.3
153.23
150.81
ug/min
0.01
19
230
10
84
1.19
0.14
1.1
1.0
—
—
—
0
0
12
104
1.15
0.12
1.2
1.3
30.35
39.34
mmol/l
0.97
12
98
75
720
1.04
0.11
1.1
1.1
—
—
—
0
0
21
192
1.09
0.10
1.4
1.4
—
—
nmol/l
—
0
0
33
310
1.07
0.10
5.4
8.7
11.43
11.50
mmol/l
0.06
28
274
24
223
1.08
0.09
1.3
1.4
—
0.26
nmol/l
—
0
18
44
420
1.05
0.08
1.7
1.6
—
—
—
0
0
31
328
0.94
0.08
1.3
1.2
36.53
24.68
u/l
0.32
31
284
8
76
1.05
0.07
1.8
3.2
15.24
17.39
%
—
8
76
281
2774
1.02
0.07
1.7
1.5
—
—
—
0
0
20
186
1.08
0.07
1.3
1.4
0.18
0.20
nmol/l
0.29
13
147
41
393
1.04
0.07
1.2
1.2
—
—
—
0
0
42
403
1.04
0.06
1.5
1.5
1.16
1.27
mm
1.18
31
297
58
561
1.03
0.06
1.6
1.5
74.69
59.49
ug/l
0.28
50
484
43
413
1.04
0.06
1.6
1.5
—
—
—
0
0
1666
16627
1.01
0.06
5.4
4.8
4.59
4.64
mmol/l
1.41
1605
15996
48
463
1.04
0.06
2.4
2.5
25.71
44.05
u/ml
0.99
48
442
12
111
1.08
0.04
2.1
2.1
0.26
3.57
u/ml
—
5
37
15
141
1.06
0.03
15.2
13.8
0.67
0.63
mmol/l
0.32
15
131
15
141
1.06
0.03
5.1
5.3
318.32
67.51
u/ml
—
8
44
17
161
1.06
0.03
1.1
1.1
4.47
5.93
iu/ml
—
6
46
45
439
1.03
0.03
2.0
2.6
—
—
—
0
0
13
122
1.07
0.02
1.7
1.6
7.30
6.56
mmol/l
—
7
85
15
158
0.95
0.02
1.1
1.2
—
—
—
0
0
10
106
0.94
0.01
1.6
1.6
—
—
—
0
0
12
115
1.04
0.00
1.1
1.2
9.00
7.97
mm/h
0.11
12
115
23
225
1.02
0.00
1.2
1.4
70.39
149.86
pmol/l
0.78
23
217
99
991
1.00
0.00
1.8
1.6
1049.62
962.06
mu/l
0.23
86
855
1657
16571
1.00
0.00
5.4
4.7
1.35
1.36
mmol/l
0.99
1589
15882
37
374
0.99
0.00
1.1
1.1
0.19
0.84
u/ml
0.61
11
141
0
5
0.00
0.00
0.0
1.6
—
1.38
—
0
5
0
6
0.00
0.00
0.0
1.0
—
36.58
—
0
6
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
7
72
0.97
0.00
10.6
8.2
1.64
412.32
ug/l
—
7
52
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
8.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
363.00
—
0
6
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
38.48
—
0
5
0
5
0.00
0.00
0.0
1.0
—
173.80
—
0
5
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
29.09
—
0
7
8
83
0.96
-0.00
1.8
1.2
197.13
201.30
mmol/24h
—
8
83
7
78
0.90
-0.00
1.7
3.1
8.01
7.98
mmol/l
—
7
78
5
49
1.02
-0.00
1.4
1.4
9.90
9.73
g/l
—
5
33
9
99
0.91
-0.00
2.7
2.2
235.78
143.32
nmol/l
—
9
90
8
87
0.92
-0.00
1.1
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
-0.00
1.0
1.1
21.08
42.32
iu/ml
—
6
63

Mortality – FinRegistry

Association

Association between endpoint AB1_VARICELLA and mortality.

Females

Parameter HR [95% CI] p-value
AB1_VARICELLA 2.371 [1.77, 3.17] < 0.001
Birth year 0.998 [0.99, 1.01] 0.578

During the follow-up period (1.1.1998 — 31.12.2019), 230 out of 5335 females with AB1_VARICELLA died.

Males

Parameter HR [95% CI] p-value
AB1_VARICELLA 2.514 [1.95, 3.24] < 0.001
Birth year 0.989 [0.98, 1.0] 0.018

During the follow-up period (1.1.1998 — 31.12.2019), 291 out of 6337 males with AB1_VARICELLA died.

Mortality risk

Mortality risk for people of age

years, who have AB1_VARICELLA.

N-year risk Females Males
1 0.272% 0.409%
5 1.555% 2.968%
10 3.899% 7.396%
15 7.226% 14.074%
20 12.554% 22.812%

Relationships between endpoints

Index endpoint: AB1_VARICELLA – Varicella [chickenpox]

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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