No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
120 |
4. Check minimum number of eventsNone |
120 |
5. Include endpointsNone |
120 |
6. Filter based on genotype QC (FinnGen only) |
103 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Idiopathic hypoparathyroidism
based on the number of shared cases.
Similar with more cases:
- Hypoparathyroidism
- Disorders of parathyroid gland
- Disorders of other endocrine glands
- Endocrine, nutritional and metabolic diseases
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 103 | 73 | 30 |
| Unadjusted period prevalence (%) | 0.02 | 0.03 | 0.01 |
| Median age at first event (years) | 54.33 | 53.21 | 57.03 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 110
- Matched controls
- 1100
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E20.0
ICD-10 Finland
Idiopathic hypoparathyroidism
+∞
158.7
110
*
106
Kela drug reimbursment
Hypoparathyroidism
+∞
52.3
46
*
A11CC03
ATC
alfacalcidol; systemic
155.5
51.3
51
6
A12AA04
ATC
calcium carbonate; oral
160.8
41.1
41
*
E20.9
ICD-10 Finland
Hypoparathyroidism, unspecified
+∞
30.7
28
*
A11CC02
ATC
dihydrotachysterol; oral
388.9
30.4
29
*
E83.51
ICD-10 Finland
Hypocalcemia
176.8
27.0
27
*
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
64.8
25.8
29
6
A12AA06
ATC
calcium lactate gluconate; oral
+∞
19.3
18
*
E20.8
ICD-10 Finland
Other hypoparathyroidism
+∞
17.1
16
*
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
185.3
15.9
16
*
104
Kela drug reimbursment
Thyroid insufficiency
5.4
10.6
24
54
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.7
10.2
66
319
KA1AE
NOMESCO Finland
Kidney ultrasound examination
17.6
9.3
14
9
E20
ICD-10 Finland
Hypoparathyroidism
+∞
8.4
8
*
E21.0
ICD-10 Finland
Primary hyperparathyroidism
13.2
8.3
14
12
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
16.6
7.9
12
8
E83.50
ICD-10 Finland
Hypercalcemia
15.1
7.1
11
8
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
24.3
6.8
9
*
H03AA01
ATC
levothyroxine sodium; systemic
3.0
6.7
42
189
Z3231
NOMESCO Finland
Registered nurse
2.8
6.4
47
230
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
19.4
6.4
9
5
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
53
84
11.25
35.88
4.9
4.3
56.67
78.84
ng/l
0.84
39
70
87
509
4.39
9.99
25.7
7.7
1.15
1.22
mmol/l
5.71
80
437
11
9
13.40
6.74
1.5
1.3
113.45
103.44
pmol/l
—
11
9
21
64
3.82
6.24
1.1
1.2
45.08
209.36
u/ml
—
5
22
8
8
10.66
4.60
1.5
7.6
—
—
—
0
0
12
27
4.86
4.07
3.4
2.9
4.03
9.39
pmol/l
1.04
12
27
7
12
6.14
3.07
1.4
1.8
—
—
—
0
0
5
5
10.38
3.01
1.8
1.4
89.12
79.40
ng/l
—
5
5
71
529
1.97
2.85
5.2
4.3
0.00
0.00
estimate
-0.00
18
124
71
531
1.95
2.79
5.2
4.3
0.00
0.00
estimate
-0.00
19
128
14
55
2.77
2.74
2.1
2.7
1.42
1.41
g/l
0.01
14
49
8
19
4.45
2.73
1.6
1.8
—
—
—
0
0
6
10
6.27
2.73
11.2
2.1
13.37
4.16
nmol/l
—
6
10
5
7
7.41
2.57
2.0
3.3
—
—
—
0
0
71
540
1.89
2.56
5.2
4.4
0.00
0.00
estimate
-0.00
18
115
56
400
1.81
2.43
5.2
4.2
0.00
0.00
estimate
-0.00
12
100
11
39
3.02
2.42
6.7
3.6
8.63
8.72
kpa
0.06
11
39
8
23
3.67
2.32
1.4
1.8
—
—
—
0
0
8
25
3.37
2.14
1.8
1.7
—
—
—
0
0
7
21
3.49
2.00
2.6
3.1
14.36
15.52
%
—
7
21
9
33
2.88
1.98
3.6
2.6
24.46
25.02
mmol/l
—
9
33
6
16
3.90
1.96
1.8
1.7
—
—
—
0
0
104
949
2.76
1.96
38.8
19.9
3.89
3.97
mmol/l
1.95
104
930
72
576
1.72
1.94
9.1
11.0
4.57
4.15
e9/l
0.91
66
495
46
327
1.70
1.92
5.7
3.9
5.44
8.74
mg/mmol
0.65
34
195
43
301
1.70
1.89
3.7
3.4
0.16
0.33
e6/l
1.15
35
214
42
294
1.69
1.84
5.1
4.4
0.00
0.00
estimate
-0.00
19
115
104
951
2.71
1.81
38.5
19.7
140.38
139.68
mmol/l
2.16
104
934
43
307
1.66
1.73
4.4
3.7
0.00
0.00
estimate
-0.00
13
95
27
172
1.76
1.63
5.1
2.7
13.06
12.77
umol/l
0.08
27
156
22
133
1.82
1.57
2.3
1.7
—
—
—
0
0
26
166
1.74
1.56
5.0
2.6
2.39
2.29
g/l
0.54
26
151
14
74
2.02
1.47
3.1
2.9
5.18
4.25
ug/l
0.16
14
66
6
22
2.82
1.45
3.7
2.1
35.67
75.80
ug/min
—
6
13
12
61
2.09
1.39
19.8
3.2
143.00
227.84
ng/l
0.66
12
56
27
180
1.66
1.38
2.3
3.3
1.85
0.91
e6/l
0.45
17
88
24
155
1.70
1.38
5.0
2.7
25.16
22.16
%
0.41
24
140
13
69
2.00
1.35
1.6
1.6
—
—
—
0
0
15
84
1.91
1.35
2.2
3.2
0.21
0.21
g/l
0.05
15
77
13
70
1.97
1.30
11.2
11.3
26.60
25.39
mmol/l
0.40
13
70
41
310
1.51
1.23
11.1
3.6
2010.57
1277.13
ng/l
0.66
35
260
20
127
1.70
1.22
2.4
1.9
—
—
—
0
0
58
472
1.48
1.22
3.2
2.9
—
—
estimate
—
0
0
6
26
2.38
1.20
1.2
1.3
—
3.80
—
0
5
41
313
1.49
1.17
3.1
2.3
57.51
56.98
u/l
0.03
41
286
54
441
1.44
1.08
2.4
2.0
91.49
98.01
pmol/l
0.44
31
210
25
176
1.54
1.03
1.5
1.3
26.50
25.75
iu/ml
—
6
59
104
983
2.06
1.01
41.9
21.5
86.22
76.98
umol/l
1.67
104
974
24
171
1.52
0.93
2.5
1.9
—
—
—
0
0
6
28
2.21
0.93
1.3
2.6
—
—
—
0
0
6
29
2.13
0.91
1.8
1.5
—
—
—
0
0
11
65
1.77
0.86
5.9
7.9
25.57
24.81
mmol/l
0.23
11
65
12
75
1.67
0.78
2.5
3.6
57.57
59.30
ml/min/173m2
—
7
33
6
34
1.81
0.77
2.5
2.2
117.50
122.69
g/l
—
6
26
9
57
1.63
0.73
10.7
6.6
1.59
1.26
%
—
9
57
46
385
1.33
0.73
4.7
4.0
42.52
47.26
ng/l
0.08
36
283
5
26
1.97
0.71
1.2
1.2
—
—
—
0
0
15
103
1.53
0.69
2.9
4.0
—
—
—
0
0
5
27
1.89
0.69
2.2
1.4
60.80
35.44
nmol/l
—
5
27
5
29
1.76
0.64
2.0
1.6
—
—
—
0
0
28
223
1.34
0.61
5.7
4.5
1.02
1.02
kg/l
0.24
21
149
0
22
0.00
0.60
0.0
1.9
—
—
—
0
0
99
942
1.51
0.58
31.0
16.8
23.87
23.73
mg/l
0.01
90
776
6
36
1.70
0.57
6.3
3.9
93.83
95.08
%
—
6
36
17
126
1.41
0.56
20.5
5.2
261.18
245.57
u/l
0.20
17
120
21
163
1.36
0.53
1.4
1.3
1.95
10.87
u/ml
—
10
67
86
807
1.30
0.49
35.7
21.7
14.03
13.68
%
1.53
86
801
28
232
1.28
0.46
12.2
2.0
0.66
1.63
mg/l
1.53
21
176
21
168
1.31
0.44
2.7
3.6
1.60
2.41
e6/l
0.34
14
77
0
15
0.00
0.41
0.0
2.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
104
1014
1.47
0.34
42.5
25.5
253.57
252.94
e9/l
0.03
104
998
13
101
1.33
0.33
18.8
8.0
—
—
—
0
0
42
378
1.18
0.31
1.9
2.0
1.42
1.33
mmol/l
0.29
37
310
64
598
1.17
0.30
3.7
3.2
—
—
—
0
0
8
65
1.25
0.28
2.3
1.7
—
—
—
0
0
29
256
1.18
0.27
1.6
1.4
2.75
1.72
u/ml
—
8
69
17
200
0.82
0.25
1.3
1.6
—
—
—
0
0
17
200
0.82
0.25
5.2
5.3
2.79
1.64
ug/l
1.08
17
176
104
1016
1.43
0.25
43.7
26.1
39.44
39.87
%
0.54
104
1004
104
1016
1.43
0.25
43.0
25.7
130.08
132.97
g/l
1.33
104
1004
104
1016
1.43
0.25
42.2
25.4
90.31
90.88
fl
0.67
104
1004
104
1016
1.43
0.25
42.4
25.5
4.40
4.44
e12/l
0.38
104
995
5
41
1.23
0.22
1.0
3.6
8.00
807.03
u/ml
—
5
34
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
6
76
0.78
0.16
1.2
1.5
—
—
—
0
0
75
725
1.11
0.15
7.1
4.8
17.28
11.71
mm/h
1.91
75
665
26
239
1.12
0.13
3.1
2.4
—
—
—
0
0
18
164
1.12
0.10
1.2
1.3
—
—
—
0
0
6
54
1.12
0.09
1.2
1.4
—
—
—
0
0
6
57
1.06
0.08
2.3
1.7
—
—
—
0
0
7
68
1.03
0.08
15.4
7.7
25.99
25.07
mmol/l
—
7
68
11
102
1.09
0.03
3.3
2.3
—
—
—
0
0
11
118
0.92
0.03
3.3
2.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
17.63
—
0
6
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
6.72
—
0
5
0
5
0.00
0.00
0.0
3.2
—
9.62
—
0
5
0
5
0.00
0.00
0.0
1.0
—
12.40
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.2
—
4.67
—
0
5
5
51
0.98
-0.00
2.2
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
1.8
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
4.3
—
1.11
—
0
9
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: E4_IDIOPATHIC_HYPOPARATHYROIDISM – Idiopathic hypoparathyroidism
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).