Knuckle pads

M13_KNUCKLEPADS

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — M72.1 Cause of death: ICD-10 — M72.1 2 out of 7 registries used, show all original rules.	67
4. Check minimum number of events None	67
5. Include endpoints None	67
6. Filter based on genotype QC (FinnGen only)	57

Control definitions (FinnGen only)

Control exclude: M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: M72

NAME	M13_KNUCKLEPADS
CONTROL_EXCLUDE	M13_SOFTTISSUE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M721
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M721
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Knuckle pads based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	435	219	216
Only index persons	400	203	197
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	-	54.15	51.83
Only index persons	52.14	53.44	50.80

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	57	28	29
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	56.06	52.96	59.06

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
63: Matched controls
630

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

M72.1

ICD-10 Finland

Knuckle pads

+∞

90.4

NDM10

NOMESCO Finland

Palmar fasciotomy of hand

+∞

12.9

M75.1

ICD-10 Finland

Rotator cuff syndrome

6.9

12.0

N02AX02

ATC

tramadol; systemic, rectal

5.0

8.9

171

N03AX16

ATC

[U] pregabalin

5.3

8.4

M54.5

ICD-10 Finland

Low back pain

4.4

8.0

125

R10.4

ICD-10 Finland

Other and unspecified abdominal pain

4.1

7.1

140

N02AE01

ATC

buprenorphine; parenteral, sublingual, transdermal

5.3

7.1

M72.0

ICD-10 Finland

Palmar fascial fibromatosis [Dupuytren]

25.8

6.9

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3019198) Lymphocytes [#/volume] in Blood

254

2.96

4.01

5.4

6.3

1.80

1.70

e9/l

0.32

221

(3013115) Eosinophils [#/volume] in Blood

255

2.94

3.97

5.4

7.1

0.19

0.17

e9/l

0.32

214

(3006315) Basophils [#/volume] in Blood

246

2.91

3.95

5.4

6.3

0.05

0.04

e9/l

1.74

201

(42870588) Differential panel, method unspecified - Blood

170

2.79

3.87

5.1

4.5

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

305

2.88

3.48

6.9

11.8

4.35

4.30

e9/l

0.04

254

(3001604) Monocytes [#/volume] in Blood

248

2.68

3.45

5.5

6.3

0.57

0.59

e9/l

0.19

205

(3004789) Transferrin [Mass/volume] in Serum or Plasma

2.93

3.39

5.1

2.4

2.41

2.34

g/l

0.22

(3018095) Leukocytes [#/volume] in Urine

222

2.45

3.00

5.7

3.5

632.26

106.99

e6/l

0.45

148

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

2.86

2.92

2.5

4.6

235.94

257.79

u/l

0.41

(3024561) Albumin [Mass/volume] in Serum or Plasma

252

2.44

2.90

8.3

4.1

35.53

35.37

g/l

0.05

239

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

203

2.31

2.68

4.5

3.0

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

318

2.45

2.63

6.6

4.8

6.44

6.68

mmol/l

0.40

301

(3011288) Drugs identified in Urine by Screen method Nominal

7.63

2.59

2.6

1.1

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

2.53

2.54

4.2

3.1

4.12

3.29

e6/l

—

(3026008) Bacteria identified in Urine by Culture

165

2.25

2.48

6.4

3.3

—

(3021589) Normoblasts [#/volume] in Blood

245

2.24

2.46

10.9

11.8

0.00

e9/l

0.71

189

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

6.67

2.41

1.0

1.6

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

2.46

2.41

2.2

1.8

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

5.92

2.25

1.2

—

(3023368) Bacteria identified in Blood by Culture

154

2.17

2.23

4.0

3.9

—

(3018418) pH of Serum or Plasma

189

2.12

2.19

5.5

4.4

7.39

7.40

0.21

132

(36304419) Bacteria [Presence] in Urine

155

2.15

2.19

5.0

2.9

—

estimate

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.53

2.13

2.3

1.8

—

(3019060) Gas panel - Arterial blood

3.11

2.10

5.6

4.7

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

2.28

2.06

4.1

2.9

0.77

1.47

e6/l

—

(3049717) Cytology report of Urine Cyto stain

3.61

2.03

2.1

3.1

—

(3037467) Urinalysis macro (dipstick) panel - Urine

358

2.23

2.03

7.5

4.1

—

(3013707) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method

380

2.30

2.01

4.6

4.0

13.69

12.84

mm/h

0.14

344

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

416

2.43

1.94

9.9

7.4

84.52

79.19

u/l

0.36

387

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.36

1.87

2.3

1.6

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

3.29

1.86

2.7

2.1

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

3.15

1.78

1.1

1.0

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

229

1.93

1.74

3.0

2.1

92.94

94.80

pmol/l

0.08

115

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

134

1.99

1.69

3.4

2.4

—

(40768797) Stomach Pathology biopsy report

2.30

1.68

1.0

1.3

—

(3005895) Myoglobin [Mass/volume] in Serum or Plasma

3.78

1.65

1.2

1.6

2035.80

232.50

ug/l

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

246

1.83

1.52

3.5

2.6

—

estimate

—

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

2.52

1.50

9.2

3.2

108.56

76.35

ng/l

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

3.30

1.46

3.4

1.5

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

107

1.96

1.46

3.3

3.4

28.72

319.86

ng/l

0.68

(3001122) Ferritin [Mass/volume] in Serum or Plasma

223

1.77

1.37

6.4

3.0

83.54

129.97

ug/l

1.75

210

(3019832) Treponema pallidum Ab [Presence] in Serum

2.27

1.37

2.3

1.5

—

(3027945) Reticulocytes/Erythrocytes in Blood

2.08

1.36

2.3

3.0

1.59

1.69

0.16

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.65

1.34

1.0

1.6

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

2.05

1.31

2.8

1.5

—

(40758558) Short blood count panel - Blood

162

1.78

1.31

3.9

7.5

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

284

1.73

1.28

3.3

2.9

—

(1761868) Lipid panel - Serum or Plasma

211

0.52

1.28

3.0

3.1

—

(3023081) Carboxyhemoglobin/Hemoglobin.total in Blood

2.54

1.27

3.5

4.6

1.57

1.73

—

(40768443) Skin Pathology biopsy report

2.50

1.11

1.0

—

(3000494) Fungus identified in Specimen by Culture

1.94

1.09

1.2

1.4

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

1.90

1.09

1.4

1.2

1.20

5.15

u/ml

—

(3044640) Blood type and Crossmatch panel - Blood

189

1.64

1.05

2.8

2.3

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.06

1.00

1.7

1.6

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

528

2.24

1.00

28.5

18.4

3.96

3.97

mmol/l

0.08

513

(3019550) Sodium [Moles/volume] in Serum or Plasma

527

2.26

1.00

28.3

18.3

139.60

139.74

mmol/l

0.15

512

(40768804) Tissue Pathology biopsy report

219

1.60

1.00

2.5

2.3

—

(3044889) 12 lead EKG panel

378

1.67

0.99

4.1

4.2

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

113

1.69

0.95

1.6

1.4

1.10

1.41

mg/l

0.23

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.93

0.94

3.2

1.6

—

(3042936) Bacteria identified in Isolate by Culture

1.79

0.93

2.6

1.9

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

2.03

0.93

4.6

3.0

5.19

5.07

kpa

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.03

0.87

7.7

4.9

22.43

24.24

mmol/l

—

(3030981) Hyaline casts [#/volume] in Urine by Automated count

1.76

0.82

2.5

2.2

0.43

1.96

e6/l

—

(3022145) Colonoscopy Study observation

1.83

0.81

1.2

1.3

—

(3022313) Gas panel - Capillary blood

2.08

0.74

5.2

3.4

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.79

0.73

1.9

1.4

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

2.00

0.72

1.0

1.3

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.70

0.69

1.0

4.1

—

(3035350) Ketones [Presence] in Urine by Test strip

282

1.45

0.69

4.9

4.0

135.55

0.00

estimate

0.47

(3028026) IgM [Mass/volume] in Serum or Plasma

1.85

0.67

1.2

1.7

0.98

1.08

g/l

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.62

0.65

16.8

4.5

1.07

1.03

mmol/l

0.19

(3007853) Bacteria identified in Skin by Aerobe culture

1.65

0.63

3.7

1.4

—

(3025941) Bacteria identified in Stool by Culture

1.72

0.63

1.0

1.3

—

(3014007) Fractional oxyhemoglobin in Arterial blood

1.84

0.60

14.7

9.6

94.23

92.19

—

(3012516) Albumin [Mass/volume] in Urine

174

1.41

0.55

5.3

3.1

44.69

56.86

mg/l

0.13

111

(3009261) Glucose [Presence] in Urine by Test strip

290

1.37

0.55

4.8

4.0

0.00

estimate

—

(3013512) EKG study

175

1.40

0.53

3.8

4.0

—

(3021601) Nitrite [Presence] in Urine by Test strip

281

1.37

0.53

4.8

4.0

0.00

estimate

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

1.62

0.51

1.6

1.4

—

(3000991) Gas panel - Venous blood

1.45

0.47

16.6

7.3

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

162

1.34

0.43

3.9

4.7

16.88

21.69

—

(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method

0.00

0.42

0.0

2.2

—

3.59

—

(4034850) Laboratory test

0.00

0.42

0.0

9.0

—

(3037756) Immunofixation for Serum or Plasma

0.00

0.41

0.0

2.4

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

555

1.57

0.38

29.8

20.3

91.05

80.09

umol/l

0.53

546

(3002385) Erythrocyte [DistWidth] in Red Blood Cells

445

1.33

0.36

27.7

19.4

13.87

13.74

0.23

436

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.44

0.36

2.3

2.0

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.39

0.35

3.7

1.8

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

212

0.79

0.30

5.3

4.2

0.00

0.07

estimate

—

(3017446) Testosterone [Moles/volume] in Serum or Plasma

1.33

0.29

2.9

2.0

11.26

13.52

nmol/l

—

(40760892) CBC W Ordered Manual Differential panel - Blood

114

1.29

0.28

3.1

5.7

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

269

1.22

0.27

11.8

6.1

1.20

1.21

mmol/l

0.38

241

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.21

0.26

12.2

6.0

106.00

104.51

mmol/l

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.30

0.24

1.5

1.6

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.34

0.24

2.4

1.7

—

(3003694) ABO and Rh group [Type] in Blood

155

0.80

0.23

1.9

1.4

—

(3025159) Blasts/Leukocytes in Blood

1.27

0.23

3.2

4.7

—

0.40

—

(36660697) Celiac disease serology panel - Serum

1.24

0.22

1.2

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.21

0.0

1.7

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(44790048) Parainfluenza type 2 nucleic acid detection

0.00

0.21

0.0

1.8

—

(44806118) Parainfluenza type 4 nucleic acid detection

0.00

0.21

0.0

1.8

—

(44790047) Parainfluenza type 1 nucleic acid detection

0.00

0.21

0.0

1.8

—

(44790049) Parainfluenza type 3 nucleic acid detection

0.00

0.21

0.0

1.7

—

(3000492) Spirometry study

1.28

0.21

1.2

1.6

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

4.0

—

14.38

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.21

0.0

1.8

—

(40761536) Microorganisms panel - Urine sediment

1.25

0.21

6.3

3.0

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

1.22

0.20

2.0

2.5

4.68

10.29

ug/l

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.20

0.0

4.1

—

(3007164) IgA [Mass/volume] in Serum or Plasma

101

1.23

0.18

1.2

1.6

2.34

2.58

g/l

—

(3015736) pH of Urine

219

1.15

0.16

4.8

3.9

6.12

6.27

0.19

114

(3002256) Pathology report gross observation

1.13

0.16

1.6

1.4

—

(3020682) Albumin/Creatinine [Ratio] in Urine

180

1.16

0.15

6.0

3.9

8.21

9.43

mg/mmol

0.06

112

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

212

1.13

0.12

4.1

5.2

1.87

1.86

ug/l

0.01

185

(3041096) Erythrocytes [Presence] in Urine by Automated

156

0.87

0.11

5.8

3.2

0.00

estimate

—

(3029937) Albumin [Presence] in Urine by Test strip

155

1.13

0.10

5.0

4.5

0.00

0.03

estimate

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

1.12

0.09

1.0

4.3

1.25

1.23

mmol/l

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

117

1.14

0.09

2.6

1.9

464.23

118182219.62

pmol/l

0.50

(40761511) CBC panel - Blood by Automated count

539

1.16

0.07

17.6

13.8

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

208

1.09

0.06

3.2

4.3

43.60

40.30

ng/l

0.05

155

(3019150) Specific gravity of Urine by Refractometry

114

1.07

0.01

4.4

5.0

1.01

1.02

kg/l

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

0.0

1.3

—

9.63

—

(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid

0.00

0.0

1.3

—

7.33

—

(3044941) Cell count panel - Synovial fluid

0.00

0.0

1.5

—

(4268621) Lupus anticoagulant assay

0.00

0.0

2.5

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.0

1.5

—

(3003434) Protein [Mass/volume] in Pleural fluid

0.00

0.0

2.0

—

33.80

—

(21494434) Karyotype in Bone marrow

0.00

0.0

1.0

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(3025130) Human papilloma virus identified in Specimen

0.00

-0.00

0.0

2.0

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

-0.00

0.0

1.6

—

201.20

—

(44806420) Estimation of glomerular filtration rate

0.00

-0.00

0.0

1.8

—

(3035947) Staphylolysin Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3004451) EKG impression Narrative

0.00

-0.00

0.0

1.4

—

(3042631) Mycobacterium sp identified in Specimen

0.00

-0.00

0.0

2.0

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.4

—

(3000034) Microalbumin [Mass/volume] in Urine

0.00

-0.00

0.0

4.8

—

11.54

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

-0.00

0.0

1.5

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

-0.00

0.0

2.0

—

1.40

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.6

—

3.96

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.6

—

1.16

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

23.9

—

1663.14

—

(40768806) Pleura Pathology biopsy report

0.00

-0.00

0.0

3.4

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

-0.00

0.0

6.9

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

-0.00

0.0

1.0

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

160.78

—

(3032700) Glomerular basement membrane Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

(3009466) Valproate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.8

—

334.20

—

(3012441) Differential panel - Pleural fluid

0.00

-0.00

0.0

2.0

—

(3044927) Protein electrophoresis panel - Urine

0.00

-0.00

0.0

1.0

—

(3019230) Fractional oxyhemoglobin in Venous blood

0.00

-0.00

0.0

1.3

—

62.09

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

-0.00

0.0

1.6

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.1

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.02

-0.00

1.3

1.4

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.6

—

108.40

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

-0.00

0.0

1.0

—

89.84

—

(3045142) Bone marrow Pathology biopsy report

0.00

-0.00

0.0

1.1

—

(40768795) Lymph node Pathology biopsy report

0.00

-0.00

0.0

1.1

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.98

-0.00

3.6

9.0

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

-0.00

0.0

1.4

—

6.46

—

(3051651) Icteric interference index of Serum or Plasma

0.00

-0.00

0.0

2.4

—

0.60

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

-0.00

0.0

1.1

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

0.88

-0.00

4.3

3.5

—

Mortality – FinRegistry

↥

Association

Association between endpoint M13_KNUCKLEPADS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_KNUCKLEPADS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: M13_KNUCKLEPADS – Knuckle pads

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Knuckle pads

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints