breast ductal carcinoma in situ: A carcinoma entirely confined to the mammary ducts. It is also known as DCIS. There is no evidence of invasion of the basement membrane. Currently, it is classified into three categories: High-grade DCIS, intermediate-grade DCIS and low-grade DCIS. In this classification the DCIS grade is defined by a combination of nuclear grade, architectural growth pattern and presence of necrosis. The size of the lesion as well as the grade and the clearance margins play a major role in dictating the most appropriate therapy for DCIS.
Carcinoma in situ of breast, other/unspecified
DOID EFO Endpoint Browser PheWeb
CD2_INSITU_BREAST_NOS
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleonly females |
313377 |
2. Check conditionsNone |
313377 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
539 |
4. Check minimum number of eventsNone |
539 |
5. Include endpointsNone |
539 |
6. Filter based on genotype QC (FinnGen only) |
485 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Carcinoma in situ of breast, other/unspecified
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 485 | 485 | - |
| Unadjusted period prevalence (%) | 0.17 | 0.17 | - |
| Median age at first event (years) | 58.85 | 58.85 | - |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 505
- Matched controls
- 5050
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D05.9
ICD-10 Finland
Carcinoma in situ of breast, unspecified
+∞
307.7
361
*
8500/2-C50.9
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of breast, NOS
75.6
307.7
187
39
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
74.6
307.7
274
79
PJA12
NOMESCO Finland
Sentinel node biopsy
9.4
139.5
242
451
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
10.5
130.7
180
253
HAB40
NOMESCO Finland
Wedge excision of mammary gland
9.8
130.2
195
304
HAC20
NOMESCO Finland
Total mastectomy
11.4
126.1
156
190
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
22.2
105.3
81
43
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
19.4
104.4
86
53
C50.99
ICD-10 Finland
Breast, unspecified
11.1
102.3
123
142
D05.7
ICD-10 Finland
Other carcinoma in situ of breast
+∞
99.3
92
*
TQW20
NOMESCO Finland
Tatoe
22.8
93.9
71
36
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
7.3
78.1
138
248
2330A
ICD-9 Finland
Carcinoma in situ of breast and genito-urinary system, Breast
+∞
70.5
66
*
HA1AA
NOMESCO Finland
X-ray mammography
5.3
66.2
180
478
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
5.5
62.6
155
378
HAC15
NOMESCO Finland
Subcutaneous mastectomy with excision of mamilla
21.8
58.0
44
22
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
6.8
57.3
101
178
Z85.3
ICD-10 Finland
Personal history of malignant neoplasm of breast
10.4
57.0
67
73
C50
ICD-10 Finland
Malignant neoplasm of breast
8.1
55.9
82
118
115
Kela drug reimbursment
Breast cancer
4.5
53.0
174
527
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
5.0
49.0
129
326
8503/2-C50.9
ICD-O-3
Noninfiltrating intraductal papillary adenocarcinoma of breast, NOS
252.4
45.8
46
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
5.8
40.9
82
162
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
4.9
37.2
92
218
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
8.6
35.9
48
61
9703
FHL
Breast resection
11.3
35.3
38
36
HAE99
NOMESCO Finland
Other reconstruction of breast
14.1
35.1
33
25
HAB00
NOMESCO Finland
Excision of lesion of mammary gland
6.2
34.7
64
116
D05.0
ICD-10 Finland
Lobular carcinoma in situ
82.1
34.3
38
5
ZZR10
NOMESCO Finland
Flap of skin and muscle
14.2
34.2
32
24
HAB99
NOMESCO Finland
Other partial excision of mammary gland
6.2
31.6
57
101
N63
ICD-10 Finland
Unspecified lump in breast
4.0
30.3
98
284
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
5.5
29.5
61
123
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
5.3
27.2
58
120
Z31.5
ICD-10 Finland
Genetic counselling
4.7
26.5
67
160
WX702
NOMESCO Finland
Supraglottic ventilation device
4.3
24.9
71
186
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.8
24.7
177
821
L02BA01
ATC
tamoxifen; oral
4.0
24.2
76
214
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
6.5
24.1
41
68
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
6.4
23.3
40
67
C50.4
ICD-10 Finland
Malignant neoplasm: Upper-outer quadrant of breast
8.6
22.9
30
37
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
4.0
22.2
70
197
N60.9
ICD-10 Finland
Benign mammary dysplasia, unspecified
20.0
21.5
32
17
9707
FHL
Ablation of mammae and removal of axillary lymph nodes
22.7
21.1
30
14
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
6.5
20.9
35
57
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
9.1
20.8
26
30
WZC00
NOMESCO Finland
Treatment plan or consultation
2.4
20.3
245
1427
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
5.0
20.3
46
100
L02BG04
ATC
letrozole; oral
3.0
20.1
101
383
ZX080
NOMESCO Finland
Image guided radiotherapy
5.6
19.5
38
72
WX402
NOMESCO Finland
General anaesthesia
2.5
18.4
157
777
C50.81
ICD-10 Finland
Overall malignant tumor of the mammary gland, ductal tumor
5.8
18.1
34
62
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
6.3
18.0
31
52
D05
ICD-10 Finland
Carcinoma in situ of breast
186.3
17.6
18
*
Z80.3
ICD-10 Finland
Family history of malignant neoplasm of breast
5.5
17.5
35
68
XX3DW
NOMESCO Finland
Time consuming IT work
2.8
15.6
93
383
X76
ICPC
Malignant neoplasm breast female
4.6
15.5
38
88
HA1AA, ,
SPAT
4.5
15.3
38
89
HA1AE, ,
SPAT
4.4
15.1
39
94
WF003
NOMESCO Finland
Adjuvant radiotherapy
4.5
15.1
38
90
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.3
15.0
40
99
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
3.8
14.4
46
130
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
4.1
13.8
39
101
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
4.2
13.7
38
97
A04AA02
ATC
granisetron; systemic, transdermal
2.9
13.0
64
237
H02AB02
ATC
dexamethasone; systemic
2.4
12.7
101
476
PJ5YQ, ,
NOMESCO Finland
133.2
12.5
13
*
9702
FHL
Breast exploration and possible tumor removal
4.9
12.0
27
58
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
3.8
11.7
37
104
HAD20
NOMESCO Finland
Liposuction of breast
66.5
11.7
13
*
8500/2-C50.4
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of upper-outer quadrant of breast
66.5
11.7
13
*
HAD99
NOMESCO Finland
Other plastic operation on breast
9.6
11.6
23
25
ZZF00
NOMESCO Finland
Graft of adipose tissue
10.4
11.6
22
22
ZZQ10
NOMESCO Finland
Free microvascular graft of skin and muscle
15.5
11.4
18
12
D48.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Breast
4.5
11.4
28
65
TQB05
NOMESCO Finland
Puncture of skin of trunk
9.9
11.4
22
23
9706
FHL
Ablation mammae, includes axillary exploration
35.9
11.3
14
*
5702
FHL
Local lymph node removal (eg armpit, groin)
17.5
11.3
17
10
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
4.3
11.0
29
71
1744A
ICD-9 Finland
Malignant neoplasm of female breast, Upper-outer quadrant
18.3
10.8
16
9
HA3ST
NOMESCO Finland
Removal of lesion of breast with radiological guidance
14.6
10.5
17
12
X21
ICPC
Breast sympt/compl female other
4.1
10.0
28
72
QBA00
NOMESCO Finland
Puncture of skin of trunk
26.6
9.9
13
5
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
3.6
9.8
32
92
HAE00
NOMESCO Finland
Reconstruction of breast using prosthesis
13.7
9.7
16
12
HAE05
NOMESCO Finland
Reconstruction of breast using soft tissue and prosthesis
9.4
9.6
19
21
HAD60
NOMESCO Finland
Replacement of prosthetic implant in breast
30.7
9.4
12
*
HA4ST
NOMESCO Finland
Labeling mammary gland pathology with sterotactic guidance
12.7
9.4
16
13
HAD40
NOMESCO Finland
Mastopexy
11.0
9.3
17
16
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
11.0
9.3
17
16
HA1CG
NOMESCO Finland
Extensive MRI examination of mammary gland with high intensity magnet
4.1
9.2
25
63
NK6AN
NOMESCO Finland
Total body bone isotope imaging
4.0
9.1
26
68
C50.9
ICD-10 Finland
Malignant neoplasm: Breast, unspecified
7.9
8.7
19
25
C50.31
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, ductal tumor
4.5
8.7
21
48
C50.19
ICD-10 Finland
Malignant tumor of the central part of the mammary gland, other or undeterminated histology
9.2
8.6
17
19
8509/2-C50.9
ICD-O-3
Solid papillary carcinoma in situ of breast, NOS
+∞
8.4
8
*
A04AD12
ATC
aprepitant; systemic
3.5
7.9
27
80
A03FA01
ATC
metoclopramide; systemic, rectal
1.8
7.8
155
1003
HAA10
NOMESCO Finland
Biopsy of mammary gland
6.9
7.7
18
27
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.5
7.6
48
202
8520/2-C50.9
ICD-O-3
Lobular carcinoma in situ, NOS, of breast, NOS
25.4
7.6
10
*
L02BG06
ATC
exemestane; oral
3.3
7.4
27
84
HWD00
NOMESCO Finland
Reoperation for deep haemorrhage in surgery of mammary gland
7.0
7.3
17
25
N64.9
ICD-10 Finland
Disorder of breast, unspecified
7.0
7.3
17
25
ZXE00
NOMESCO Finland
One hour or less
1.7
7.2
211
1515
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
2.9
7.1
33
118
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.2
7.0
63
311
C50.10
ICD-10 Finland
Malignant tumor of the central part of the mammary gland, no histological veryfication
14.0
6.9
11
8
X19
ICPC
Breast lump/mass female
4.2
6.9
18
44
C50.39
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, other or undeterminated histology
11.1
6.8
12
11
L03AA13
ATC
pegfilgrastim; parenteral
2.4
6.8
45
194
D24
ICD-10 Finland
Benign neoplasm of breast
3.3
6.8
25
78
9719
FHL
Other measure in this category
40.6
6.8
8
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
6.8
141
920
HA1DG
NOMESCO Finland
Very extensive MRI examination of mammary gland with high intensity magnet
5.6
6.7
18
33
JN4BD
NOMESCO Finland
Extensive body CT
2.1
6.5
63
319
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
6.5
251
1918
1749X
ICD-9 Finland
Malignant neoplasm of female breast, Breast (female), unspecified
18.3
6.3
9
5
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
3.5
6.2
21
62
C50.89
ICD-10 Finland
Overall malignant tumor of the mammary gland, other or undeterminated histology
6.4
6.2
15
24
C50.29
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland, other or undeterminated histology
6.4
6.2
15
24
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
6.2
201
1467
HAC10
NOMESCO Finland
Subcutaneous mastectomy with preservation of mamilla
12.7
6.1
10
8
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
274
1932
1.91
11.46
3.7
3.4
2.38
2.37
mmol/l
1.08
258
1744
99
488
2.28
11.14
3.3
3.5
—
—
—
0
0
432
3705
2.15
8.52
10.1
8.1
75.17
79.57
u/l
1.86
405
3498
85
439
2.13
8.40
4.5
3.6
1.24
1.24
mmol/l
0.20
66
374
284
2220
1.64
6.79
2.4
2.6
—
—
estimate
—
0
0
321
2633
1.60
5.93
7.6
6.2
9.89
10.43
umol/l
0.66
304
2499
321
2752
1.46
3.95
10.1
9.7
3.54
3.96
e9/l
4.09
288
2395
20
442
0.43
3.55
2.3
2.4
3.82
4.26
kpa
0.89
20
432
27
523
0.49
3.36
2.5
2.8
6.27
5.85
kpa
1.70
27
512
26
504
0.49
3.24
2.5
2.8
2.43
2.31
mmol/l
0.09
26
438
13
327
0.38
3.15
2.5
2.4
124.69
126.76
g/l
0.17
13
320
11
30
3.72
3.10
1.1
1.1
—
—
—
0
0
136
1714
0.72
2.77
3.9
3.9
8.30
6.15
mg/mmol
0.23
65
963
137
1723
0.72
2.75
3.2
3.2
5.82
6.20
mmol/l
0.65
102
1439
29
155
1.92
2.67
1.3
1.2
—
—
—
0
0
197
2329
0.75
2.59
2.1
2.2
100.82
98.92
pmol/l
0.18
87
1099
0
67
0.00
2.40
0.0
1.0
—
—
—
0
0
461
4379
1.61
2.37
19.5
16.5
77.44
76.39
ml/min/173m2
0.64
434
4084
398
3678
1.39
2.35
22.6
20.9
13.65
13.75
%
0.90
390
3626
20
98
2.08
2.35
2.7
2.4
16.30
15.71
%
0.36
20
98
87
1150
0.71
2.29
3.6
4.7
1.01
1.02
kg/l
1.55
56
771
144
1157
1.34
2.26
2.7
2.8
2.47
2.47
mmol/l
0.04
136
1045
38
593
0.61
2.26
4.7
6.9
—
—
—
0
0
106
815
1.38
2.20
2.5
2.8
0.84
0.81
mmol/l
1.71
97
756
275
2436
1.28
2.05
5.5
5.6
1.22
1.22
mmol/l
0.05
245
2229
15
292
0.50
1.95
2.2
2.8
24.99
24.68
mmol/l
0.19
15
287
80
611
1.37
1.74
5.1
4.2
4.19
10.48
ug/l
2.34
67
503
12
240
0.49
1.71
2.7
2.6
26.72
25.52
mmol/l
0.55
12
234
20
112
1.82
1.67
2.7
2.5
10.15
7.44
pmol/l
0.29
20
112
295
2677
1.25
1.64
6.6
6.5
1.22
1.22
mmol/l
0.47
227
2302
8
171
0.46
1.61
2.0
1.9
682.13
167.23
ug/l
—
8
159
71
543
1.36
1.54
2.6
2.3
9.96
6.87
umol/l
0.33
56
480
5
15
3.36
1.52
1.2
1.3
—
—
—
0
0
23
139
1.69
1.51
1.7
2.4
—
—
—
0
0
8
170
0.46
1.49
1.6
1.5
—
—
—
0
0
125
1042
1.27
1.46
1.5
1.4
—
—
—
0
0
46
333
1.42
1.39
2.3
2.7
27.76
26.40
au/ml
—
5
27
57
431
1.36
1.34
2.5
3.7
45.24
92.35
u/ml
0.67
52
417
140
1621
0.81
1.31
2.2
2.1
142.89
147.47
u/l
0.07
128
1541
31
442
0.68
1.26
4.7
5.6
1.13
1.33
mmol/l
1.00
31
434
49
637
0.74
1.17
5.8
5.1
34.45
34.19
%
0.06
29
386
76
613
1.28
1.16
3.1
4.0
1.06
1.05
mmol/l
0.09
66
549
135
1169
1.21
1.10
2.1
2.3
—
—
—
0
0
30
416
0.70
1.07
2.9
2.7
64.08
64.43
ml/min/173m2
0.01
13
174
73
886
0.79
1.04
2.0
1.7
1152.19
1221.44
nmol/l
0.21
43
644
137
1558
0.83
1.03
1.6
1.7
20.42
21.66
nmol/l
0.49
106
1289
247
2272
1.17
1.00
14.8
13.4
1.23
1.21
inr
0.24
216
1858
22
148
1.51
0.99
2.2
2.8
24.65
25.48
mmol/l
0.66
22
148
7
135
0.51
0.99
1.3
1.7
—
—
—
0
0
5
23
2.19
0.98
1.0
1.0
—
—
—
0
0
0
29
0.00
0.98
0.0
1.9
—
49.10
—
0
29
10
171
0.58
0.93
1.0
1.3
—
—
—
0
0
30
219
1.39
0.92
1.1
1.3
—
—
—
0
0
265
2464
1.16
0.90
2.6
2.5
82.83
81.46
nmol/l
0.37
238
2199
6
29
2.08
0.89
1.5
1.2
6.67
16.52
u/l
—
6
23
6
30
2.01
0.87
1.5
1.2
45.33
76.04
u/l
—
6
25
90
769
1.21
0.85
2.4
3.2
2.26
4.14
e6/l
1.57
42
345
19
129
1.49
0.84
3.8
2.9
1.89
1.74
index
—
9
61
445
4556
0.80
0.81
6.2
6.4
2.82
2.74
mmol/l
1.18
380
4178
0
26
0.00
0.78
0.0
3.8
—
202.58
—
0
26
376
3607
1.17
0.78
4.4
4.8
13.36
13.56
mm/h
0.09
331
3338
14
91
1.55
0.76
1.3
1.3
—
—
—
0
0
244
2279
1.14
0.73
4.4
4.3
36.35
35.51
g/l
1.70
221
2136
7
39
1.81
0.72
1.1
1.1
—
—
—
0
0
34
265
1.30
0.72
2.3
4.0
1.02
1.02
ratio
0.18
28
247
7
40
1.76
0.71
1.0
1.1
—
—
—
0
0
7
40
1.76
0.71
1.0
1.1
—
—
—
0
0
32
408
0.77
0.71
1.6
2.3
0.38
0.63
e6/l
0.44
32
388
5
26
1.93
0.71
1.2
1.7
—
—
—
0
0
474
4654
1.30
0.70
19.1
19.6
139.84
139.76
mmol/l
0.30
456
4555
114
1274
0.86
0.68
2.3
2.3
2.50
3.03
mg/l
1.55
93
1078
7
43
1.64
0.67
1.4
1.6
—
—
—
0
0
7
43
1.64
0.67
1.0
1.1
—
—
—
0
0
474
4660
1.28
0.63
19.3
19.7
3.93
3.95
mmol/l
0.59
454
4552
133
1205
1.14
0.63
3.3
3.7
92.55
93.32
%
0.11
128
1177
15
210
0.71
0.62
1.1
2.1
1.46
1.59
g/l
—
10
186
8
53
1.52
0.58
1.4
1.2
59.12
54.25
u/l
—
8
46
426
4354
0.86
0.56
5.9
6.8
38.78
39.42
mmol/mol
0.98
369
4040
438
4467
0.85
0.55
5.4
5.6
5.86
5.92
mmol/l
0.49
358
4068
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
16
116
1.39
0.55
3.9
2.5
0.29
0.40
iu/ml
—
10
74
6
38
1.59
0.54
1.0
1.1
—
—
—
0
0
415
4245
0.87
0.52
4.3
4.5
1.25
1.26
mmol/l
0.19
340
3834
19
247
0.76
0.51
1.1
1.1
—
—
—
0
0
97
1071
0.88
0.49
1.7
1.7
456.17
12717225.61
pmol/l
0.80
63
865
11
155
0.70
0.49
1.4
1.9
2.94
2.39
mg/l
0.13
11
124
7
110
0.63
0.49
6.1
3.9
71.29
2296.62
u/ml
—
7
105
22
277
0.78
0.48
1.6
1.9
3.71
3.48
mmol/l
0.54
15
208
7
47
1.50
0.47
1.0
1.1
—
—
—
0
0
89
985
0.88
0.47
3.5
4.1
318.72
234.91
ng/l
0.15
69
779
7
48
1.46
0.47
1.3
1.3
—
223.13
u/l
—
0
15
99
1087
0.89
0.46
2.4
2.7
5.52
7.77
e6/l
0.50
86
1010
19
241
0.78
0.44
1.2
1.3
—
—
—
0
0
6
92
0.65
0.42
1.2
1.3
—
—
—
0
0
6
92
0.65
0.42
1.2
1.3
—
—
—
0
0
5
32
1.57
0.42
1.4
1.4
—
—
—
0
0
31
368
0.83
0.41
1.9
2.1
3.38
3.23
ratio
0.45
24
303
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
24
195
1.24
0.41
2.8
2.5
0.18
0.85
g/l
1.24
19
169
94
859
1.12
0.40
2.4
3.0
1.09
1.35
e6/l
0.45
46
443
479
4737
1.22
0.40
23.9
22.2
69.62
70.81
umol/l
0.68
470
4674
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
9.87
—
0
18
5
35
1.43
0.39
1.4
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
452
4452
1.15
0.39
17.1
16.5
19.77
22.47
mg/l
1.12
370
3660
397
3883
1.10
0.39
5.3
5.0
15.07
14.97
pmol/l
0.33
343
3559
439
4458
0.88
0.39
5.2
5.4
1.63
1.61
mmol/l
0.59
371
4075
240
2501
0.92
0.38
2.9
2.7
—
—
—
0
0
12
158
0.75
0.37
2.1
1.8
—
—
—
0
0
5
37
1.35
0.37
1.4
1.3
—
—
—
0
0
11
81
1.37
0.36
1.3
1.7
—
—
—
0
0
15
117
1.29
0.35
1.9
2.2
173.73
198.41
%
0.62
15
111
35
404
0.86
0.35
1.4
1.5
—
—
—
0
0
55
491
1.13
0.35
2.3
2.3
30.18
37.41
u/l
1.26
45
397
442
4482
0.89
0.35
5.2
5.5
4.87
4.81
mmol/l
0.56
376
4122
50
446
1.13
0.33
2.3
2.8
68.13
67.08
g/l
0.45
43
407
17
207
0.82
0.30
1.3
1.6
—
—
—
0
0
7
54
1.30
0.30
1.1
1.1
—
—
—
0
0
50
555
0.89
0.30
5.2
6.4
1.69
1.42
mmol/l
0.21
41
473
299
2906
1.07
0.30
3.1
3.1
51.86
46.08
u/l
0.25
263
2687
53
479
1.12
0.29
2.1
2.0
0.22
0.21
g/l
0.86
45
449
8
64
1.25
0.27
1.4
1.6
—
—
—
0
0
8
65
1.23
0.27
1.4
1.6
—
—
—
0
0
212
2197
0.94
0.27
2.8
3.0
96.43
100.34
ug/l
0.18
188
2017
14
170
0.82
0.25
2.0
1.8
—
—
—
0
0
9
74
1.22
0.25
1.2
1.4
—
—
—
0
0
149
1557
0.94
0.24
2.1
2.4
53.15
61.86
u/l
1.03
128
1421
6
82
0.73
0.24
1.3
1.3
0.47
22.75
nmol/l
—
6
77
25
218
1.15
0.23
3.4
2.7
226.10
1030.59
u/ml
0.65
20
190
185
1918
0.94
0.23
4.1
4.5
0.08
0.05
estimate
0.19
48
421
5
39
1.28
0.23
1.0
1.0
—
—
—
0
0
113
1188
0.94
0.22
2.2
2.6
315.43
321.64
umol/l
0.23
91
1025
36
324
1.12
0.22
1.2
1.2
156.20
118.22
u/ml
0.24
30
302
481
4777
1.15
0.22
26.9
25.6
91.45
91.36
fl
0.16
468
4718
5
41
1.22
0.22
1.0
1.4
—
—
—
0
0
162
1559
1.06
0.21
3.3
2.8
27.92
31.22
u/l
0.66
153
1472
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
23.08
—
0
11
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
7.1
—
—
—
0
0
12
98
1.23
0.21
1.1
1.1
—
—
—
0
0
8
101
0.79
0.21
1.0
1.2
1.52
1.68
g/l
—
8
101
481
4778
1.14
0.21
27.0
25.7
4.36
4.37
e12/l
0.15
465
4665
481
4778
1.14
0.21
27.0
25.7
255.00
260.51
e9/l
1.30
468
4681
481
4778
1.14
0.21
27.2
26.0
39.49
39.36
%
0.29
468
4718
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
481
4779
1.14
0.20
27.1
25.9
130.56
130.98
g/l
0.32
468
4719
16
136
1.18
0.20
1.1
1.3
—
9.67
—
0
10
0
14
0.00
0.20
0.0
2.5
—
2.68
—
0
5
9
113
0.79
0.20
1.1
1.6
—
—
—
0
0
15
176
0.85
0.20
1.6
1.7
—
—
—
0
0
118
1128
1.06
0.20
1.6
1.7
1.65
1.14
mg/l
0.37
95
898
141
1359
1.05
0.18
2.9
3.3
0.47
0.44
e6/l
0.05
92
993
7
60
1.17
0.18
1.1
1.3
—
—
—
0
0
215
2095
1.05
0.17
2.0
1.9
1.28
1.32
mmol/l
0.45
145
1733
7
61
1.15
0.17
1.1
1.3
—
—
—
0
0
7
61
1.15
0.17
1.1
1.3
—
—
—
0
0
7
62
1.13
0.17
1.0
1.0
—
—
—
0
0
138
1331
1.05
0.17
4.0
4.0
0.04
0.01
estimate
0.42
50
421
11
131
0.84
0.17
1.4
1.3
—
—
—
0
0
15
129
1.17
0.17
1.4
1.9
92.80
96.92
%
0.22
15
124
473
4700
1.10
0.17
14.8
12.9
24.67
23.00
u/l
0.50
451
4547
69
729
0.94
0.16
1.4
1.4
—
—
—
0
0
40
370
1.09
0.16
1.4
1.6
—
—
—
0
0
156
1609
0.96
0.16
2.9
3.0
949.58
1042.41
ng/l
0.23
132
1385
34
312
1.10
0.16
2.3
3.2
4.47
4.44
pmol/l
0.04
27
274
34
368
0.92
0.15
1.7
1.4
1.25
1.41
%
1.07
28
315
7
88
0.79
0.14
1.3
1.2
—
97.14
—
0
7
8
97
0.82
0.14
1.4
1.4
—
—
—
0
0
33
356
0.92
0.13
1.2
1.2
99.00
155.26
u/ml
0.72
13
143
9
107
0.84
0.13
1.3
1.2
1.08
0.93
g/l
—
9
107
94
974
0.96
0.12
1.3
1.3
18.67
12.66
u/ml
0.21
31
355
184
1880
0.97
0.12
3.8
3.8
26.26
77.96
ng/l
0.87
144
1372
260
2640
0.97
0.11
4.0
4.6
0.00
0.02
estimate
1.23
56
524
19
172
1.11
0.11
1.2
1.3
—
2.07
—
0
20
101
1043
0.96
0.11
1.3
1.3
45.43
33.61
iu/ml
0.21
27
336
67
643
1.05
0.11
1.7
1.9
—
—
—
0
0
34
320
1.07
0.10
2.0
1.8
—
—
—
0
0
5
45
1.11
0.10
1.2
1.0
—
—
—
0
0
5
45
1.11
0.10
1.2
1.2
—
—
—
0
0
5
47
1.06
0.09
1.4
1.6
—
—
—
0
0
79
816
0.96
0.09
2.5
2.3
12.12
12.31
umol/l
0.09
68
761
6
57
1.05
0.08
2.2
1.5
4.08
71.64
u/ml
—
6
57
5
60
0.83
0.08
1.2
1.2
—
—
—
0
0
7
64
1.10
0.08
1.1
1.3
—
—
—
0
0
7
64
1.10
0.08
1.0
1.3
—
—
—
0
0
7
64
1.10
0.08
1.1
1.3
—
—
—
0
0
17
184
0.92
0.07
1.2
1.5
—
—
—
0
0
10
111
0.90
0.06
1.4
1.5
—
—
—
0
0
24
253
0.95
0.05
1.4
1.5
—
—
—
0
0
13
141
0.92
0.05
2.5
1.4
—
—
—
0
0
73
713
1.03
0.05
2.2
2.3
22.13
21.07
%
0.23
62
667
14
151
0.93
0.05
1.7
1.8
4.45
3.70
iu/l
—
5
59
78
763
1.03
0.05
2.3
2.3
2.23
2.37
g/l
1.40
65
707
143
1450
0.98
0.05
3.9
4.6
0.00
0.00
estimate
0.50
56
506
16
150
1.07
0.04
1.1
1.2
—
—
—
0
0
179
1808
0.98
0.04
3.6
4.2
122.74
111.29
e6/l
0.06
117
1259
15
160
0.94
0.04
1.1
1.2
—
—
—
0
0
437
4384
0.98
0.04
6.4
6.3
1.84
1.93
mu/l
1.11
389
4040
60
613
0.98
0.04
1.7
1.9
—
—
—
0
0
15
141
1.07
0.03
1.1
1.3
—
—
—
0
0
15
159
0.94
0.03
1.1
1.2
—
—
—
0
0
172
1707
1.01
0.02
2.8
3.4
—
—
—
0
0
281
2822
0.99
0.02
4.0
4.5
6.48
6.60
mmol/l
0.55
273
2682
85
840
1.01
0.02
1.9
1.9
—
—
—
0
0
24
232
1.04
0.02
2.7
3.2
1.89
2.31
mmol/l
0.26
16
181
50
491
1.02
0.02
2.5
3.1
63.54
77.49
ng/l
1.10
37
431
117
1160
1.01
0.02
1.2
1.3
0.59
1.90
u/ml
1.91
28
296
11
117
0.94
0.01
1.4
1.6
—
—
—
0
0
258
2588
0.99
0.01
4.0
4.5
0.00
0.00
estimate
-0.00
55
525
10
94
1.07
0.01
1.9
1.3
—
—
—
0
0
14
136
1.03
0.00
2.0
1.6
—
—
—
0
0
27
275
0.98
0.00
2.9
3.3
5.03
5.23
kpa
0.86
27
267
10
97
1.03
0.00
1.3
1.4
—
—
—
0
0
10
103
0.97
0.00
1.5
1.6
—
—
—
0
0
17
167
1.02
0.00
1.1
1.3
292.79
297.39
ug/g
—
8
96
16
158
1.01
0.00
4.8
3.6
1.27
2.35
ratio
1.50
11
94
48
477
1.01
0.00
2.0
2.0
372.84
381.94
nmol/l
0.12
43
444
12
121
0.99
0.00
1.3
1.6
—
—
—
0
0
158
1582
1.00
0.00
2.8
3.4
31.27
54.46
e6/l
0.65
107
1208
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
9.25
—
0
8
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
0.00
5.4
5.3
12.26
13.85
mg/l
—
5
51
0
6
0.00
0.00
0.0
1.0
—
7.69
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
7.77
—
0
8
0
6
0.00
0.00
0.0
1.3
—
50.03
—
0
6
0
8
0.00
0.00
0.0
2.4
—
0.75
—
0
8
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
6.00
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
15.40
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
97.40
—
0
5
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
261
2610
1.00
-0.00
3.9
4.5
0.00
6.37
estimate
0.80
60
550
8
83
0.96
-0.00
1.6
1.5
—
—
—
0
0
7
78
0.90
-0.00
1.4
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_INSITU_BREAST_NOS – Carcinoma in situ of breast, other/unspecified
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).