Other and unspecified hypertrophic disorders of skin

L12_HYPERTROPHICNAS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

295

4. Check minimum number of events

None

295

5. Include endpoints

None

295

6. Filter based on genotype QC (FinnGen only)

250

Control definitions (FinnGen only)

Control exclude
L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1556 1015 529
Only index persons 1482 982 500
Unadjusted period prevalence (%)
Whole population 0.02 0.03 0.01
Only index persons 0.03 0.04 0.02
Median age at first event (years)
Whole population 42.51 42.48 42.83
Only index persons 42.62 42.36 43.15

-FinnGen-

Key figures

All Female Male
Number of individuals 250 175 75
Unadjusted period prevalence (%) 0.05 0.06 0.03
Median age at first event (years) 50.79 48.37 56.43

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
268
Matched controls
2680
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L91.8
ICD-10 Finland
Other hypertrophic disorders of skin
3412.5
176.7
151
*
L91.9
ICD-10 Finland
Hypertrophic disorder of skin, unspecified
1129.4
139.0
124
*
L91.0
ICD-10 Finland
Hypertrophic scar
278.7
65.3
64
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
6.1
22.4
43
82
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
119.4
20.9
22
*
L90.5
ICD-10 Finland
Scar conditions and fibrosis of skin
48.0
15.3
18
*
QAE20
NOMESCO Finland
Excision and repair of scar or web of skin of head or neck
+∞
14.7
14
*
TQW99
NOMESCO Finland
Other minor procedure on skin
5.5
14.7
30
60
S18
ICPC
Laceration/cut
2.6
13.7
149
861
QBE30
NOMESCO Finland
Excision and repair of surgical scar in trunk
52.7
13.0
15
*
SPAT1153
SPAT
Removal of sutures
2.7
12.9
99
480
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
4.3
12.4
34
87
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
11.8
140
826
J01FF01
ATC
clindamycin; systemic
2.6
11.7
93
455
ZZF00
NOMESCO Finland
Graft of adipose tissue
16.4
11.0
17
11
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.4
10.7
103
547
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
4.2
10.4
29
75
D07AD01
ATC
clobetasol; topical
2.8
10.2
58
238
HAC20
NOMESCO Finland
Total mastectomy
5.3
9.7
20
40
ZZA00
NOMESCO Finland
Split skin graft
13.0
9.5
16
13
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.6
8.2
28
84
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.7
8.2
27
79
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.9
8.2
42
162
D02AE01
ATC
carbamide; topical
3.8
7.9
25
71
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.9
7.7
40
155
J01DB01
ATC
cefalexin; oral
2.9
7.6
237
1945
R06.2
ICD-10 Finland
Wheezing
4.2
7.5
20
50
WX402
NOMESCO Finland
General anaesthesia
2.2
7.3
72
378
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.2
7.0
69
362
TQW40
NOMESCO Finland
Remowal of suture of skin
3.3
7.0
27
88
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.8
6.9
36
140
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.5
6.9
17
40
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
6.8
77
427
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.6
6.6
22
65
WX882
NOMESCO Finland
High dependency care
7.7
6.5
14
19
H04.10
ICD-10 Finland
Dry eye syndrome
2.6
6.5
41
176
QBJ30
NOMESCO Finland
Correction of abdominal apron
14.8
6.4
10
7
WZC00
NOMESCO Finland
Treatment plan or consultation
1.9
6.4
112
722
E0000UV, ,
ATC
1.9
6.4
122
810
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
18.6
6.3
9
5
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.9
6.1
125
846
N02AX02
ATC
tramadol; systemic, rectal
1.9
6.0
114
751

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
150
914
2.46
11.72
6.3
4.5
35.68
36.46
g/l
0.86
138
875
148
943
2.27
9.84
10.8
8.9
1.12
1.14
inr
0.33
126
776
126
753
2.27
9.77
2.9
2.2
—
—
—
0
0
165
1112
2.26
9.41
3.2
2.7
—
—
estimate
—
0
0
118
700
2.23
9.17
3.7
2.6
54.31
69.66
u/l
0.94
108
655
187
1370
2.21
8.10
10.1
10.5
3.99
4.01
e9/l
0.05
172
1193
171
1215
2.13
7.95
7.1
6.2
0.54
0.55
e9/l
0.15
158
1049
146
980
2.08
7.89
7.4
6.2
1.21
1.22
mmol/l
0.95
137
907
171
1218
2.12
7.86
7.1
6.2
0.04
0.04
e9/l
0.44
158
1051
54
245
2.51
7.63
2.4
1.5
—
—
—
0
0
173
1250
2.08
7.50
7.1
6.2
1.86
1.98
e9/l
0.54
162
1112
174
1263
2.08
7.41
7.2
6.5
0.19
0.19
e9/l
0.15
159
1105
93
543
2.09
7.18
2.5
2.8
323.86
330.00
umol/l
0.20
84
488
155
1090
2.00
7.08
8.3
6.9
1.21
1.22
mmol/l
0.91
132
946
178
1325
2.02
6.79
5.7
4.7
6.44
6.44
mmol/l
0.00
171
1229
119
775
1.96
6.67
3.4
3.2
2.34
2.35
mmol/l
0.52
105
711
166
1217
1.96
6.48
9.7
6.3
10.93
10.98
umol/l
0.02
160
1155
66
352
2.16
6.36
2.2
2.3
195.32
83.23
ug/g
0.86
46
275
215
1746
2.17
6.06
11.8
7.8
79.55
75.26
u/l
0.78
206
1655
116
770
1.89
5.98
7.0
5.7
—
—
—
0
0
34
138
2.68
5.98
1.9
2.1
7.62
6.11
ug/l
0.28
29
125
66
364
2.08
5.79
1.4
1.4
861.33
616.71
titre
0.23
15
79
27
99
2.92
5.72
1.4
1.9
3.54
6.13
iu/ml
—
5
23
42
194
2.38
5.65
5.6
4.1
7.35
7.33
ph
0.20
30
141
137
974
1.83
5.57
2.5
2.0
—
—
—
0
0
101
656
1.87
5.47
2.8
2.8
—
—
—
0
0
25
91
2.93
5.37
1.2
1.2
—
—
—
0
0
52
273
2.12
5.15
6.9
6.8
103.46
104.73
mmol/l
1.08
52
273
56
304
2.06
5.08
2.3
2.0
—
—
—
0
0
101
673
1.80
4.94
5.1
3.5
0.00
0.00
estimate
-0.00
37
242
27
108
2.67
4.89
5.5
8.5
—
—
—
0
0
23
85
2.87
4.82
5.5
3.9
36.98
36.93
°c
0.52
23
85
258
2333
3.84
4.79
20.6
13.2
25.28
21.16
mg/l
0.94
225
1882
85
542
1.83
4.78
4.2
4.0
—
—
—
0
0
130
947
1.72
4.58
4.3
3.4
0.00
0.00
estimate
0.50
34
216
76
474
1.84
4.56
1.4
1.3
1.29
8.18
u/ml
2.76
25
173
164
1278
1.73
4.49
4.7
3.7
0.00
1.22
estimate
0.50
41
245
55
311
1.97
4.43
1.5
1.2
—
—
—
0
0
162
1264
1.71
4.36
4.6
3.6
0.00
0.00
estimate
-0.00
41
261
147
1118
1.70
4.34
7.2
6.2
0.74
0.67
%
0.85
138
1042
19
67
2.98
4.32
3.2
1.9
10.79
11.23
mg/l
0.09
19
62
72
449
1.83
4.30
1.7
1.6
452.85
451.16
pmol/l
0.02
54
389
25
104
2.55
4.20
1.2
1.3
—
4.38
—
0
6
150
1155
1.68
4.16
7.2
6.2
28.07
28.68
%
0.34
142
1101
134
1002
1.67
4.16
4.3
3.2
6.35
6.22
ph
0.63
71
559
50
280
1.97
4.13
1.4
1.5
—
—
—
0
0
12
26
4.78
4.11
1.2
1.3
—
—
—
0
0
111
792
1.69
4.10
4.1
3.2
38.31
25.15
ng/l
0.47
77
505
67
414
1.82
4.10
2.0
2.8
2.42
2.44
mmol/l
0.34
59
371
148
1139
1.67
4.09
7.2
6.1
56.89
56.80
%
0.03
142
1092
146
1121
1.66
4.06
7.2
6.1
2.88
2.77
%
0.20
137
1050
82
544
1.73
3.93
5.0
3.6
1.02
1.02
kg/l
1.25
59
359
87
588
1.71
3.90
4.2
4.8
—
—
—
0
0
141
1081
1.64
3.88
3.2
2.5
75.65
76.49
nmol/l
0.12
132
991
39
204
2.07
3.88
2.7
4.9
3.40
6.80
ug/l
1.30
27
159
158
1248
1.65
3.85
4.7
3.6
0.00
0.00
estimate
-0.00
39
262
145
1123
1.63
3.81
7.3
6.3
8.78
8.55
%
0.43
136
1060
77
510
1.72
3.69
1.5
1.4
9.91
29.70
iu/ml
4.35
16
165
55
331
1.83
3.64
1.8
1.7
1365.34
1148.74
nmol/l
1.16
41
252
157
1250
1.62
3.61
3.6
3.0
101.83
97.04
ug/l
0.13
150
1183
53
317
1.84
3.58
2.5
2.1
2.37
2.38
g/l
0.05
48
286
87
601
1.66
3.54
1.7
1.4
2.41
2.25
g/l
0.43
63
362
27
129
2.22
3.37
1.8
2.3
—
—
—
0
0
35
186
2.01
3.34
3.7
3.9
2.71
1.39
mmol/l
1.16
30
156
11
29
3.91
3.22
1.2
1.1
—
—
—
0
0
26
127
2.16
3.09
5.1
8.6
24.98
24.54
mmol/l
0.31
26
127
17
69
2.56
3.02
1.6
1.3
215.56
303.74
ug/g
—
9
37
126
983
1.53
2.96
2.6
2.0
99.22
96.71
pmol/l
0.21
69
519
38
218
1.87
2.92
8.3
9.7
7.42
7.42
ph
0.38
28
126
35
197
1.89
2.85
3.7
3.8
5.99
5.69
kpa
0.72
35
192
38
220
1.85
2.84
8.2
9.5
1.34
0.87
mmol/l
0.44
31
178
15
59
2.63
2.84
1.0
1.3
—
—
—
0
0
47
291
1.75
2.82
4.1
3.5
4.33
5.33
e9/l
0.38
38
254
37
215
1.84
2.73
2.1
2.0
0.00
0.00
estimate
—
7
48
35
200
1.86
2.72
3.7
3.9
7.37
7.39
ph
1.61
24
103
16
67
2.48
2.69
2.1
3.1
—
—
—
0
0
19
87
2.27
2.64
5.3
2.5
—
—
—
0
0
194
1685
1.55
2.60
4.8
3.2
58.84
39.94
u/l
1.44
187
1611
31
174
1.88
2.55
8.0
8.0
—
—
—
0
0
18
83
2.25
2.47
1.7
2.6
1.41
1.34
g/l
0.10
18
75
259
2463
2.53
2.44
16.5
10.8
25.98
25.74
u/l
0.09
254
2407
242
2231
1.87
2.44
6.6
5.3
1.87
1.82
mu/l
0.29
227
2095
30
170
1.86
2.41
2.3
3.1
72.92
70.79
e9/l
0.12
22
124
33
193
1.81
2.40
4.0
3.4
—
—
—
0
0
8
24
3.40
2.20
1.5
1.5
89.94
90.39
%
—
8
24
87
665
1.46
2.11
1.4
1.3
1.52
1.86
u/ml
0.11
19
170
81
611
1.47
2.11
1.9
2.1
—
—
—
0
0
73
541
1.48
2.07
1.8
1.8
1.09
1.19
mg/l
0.11
54
424
88
677
1.45
2.06
4.3
3.6
7.40
7.40
ph
0.03
65
473
12
50
2.47
2.05
1.1
1.1
0.43
1.92
u/ml
—
7
23
85
651
1.45
2.04
3.8
3.3
24.82
63.57
mg/l
1.95
57
403
9
32
2.87
2.02
1.4
2.2
17.42
16.35
%
—
9
32
256
2429
2.20
1.99
19.8
11.7
—
—
—
0
0
73
546
1.46
1.97
5.3
3.5
—
0.00
—
0
5
12
52
2.37
1.90
1.3
1.2
—
—
—
0
0
94
742
1.41
1.89
6.4
3.1
7.81
7.87
mmol/l
0.04
81
630
8
28
2.91
1.87
1.4
1.5
1.79
1.62
mmol/l
—
8
28
6
17
3.58
1.85
2.3
2.8
—
—
—
0
0
21
116
1.88
1.84
2.1
3.4
0.69
0.60
%
0.74
21
116
12
53
2.32
1.83
1.8
3.0
7.42
7.42
ph
0.04
12
53
47
327
1.53
1.79
1.6
1.6
—
—
—
0
0
231
2143
1.56
1.76
6.8
5.5
38.42
38.17
mmol/mol
0.16
215
2034
85
667
1.40
1.75
4.5
3.9
4.39
11.04
mg/mmol
1.81
56
396
8
30
2.72
1.74
1.9
1.3
—
—
—
0
0
7
24
2.97
1.73
2.9
3.4
—
—
—
0
0
13
62
2.15
1.68
1.0
1.1
1.69
2.63
u/ml
—
8
34
8
31
2.63
1.67
1.0
1.3
—
—
—
0
0
92
739
1.37
1.64
3.3
3.0
9.16
135.52
e6/l
0.80
75
554
5
14
3.62
1.62
1.0
1.1
—
—
—
0
0
23
137
1.74
1.61
1.7
1.1
—
—
—
0
0
6
20
3.04
1.59
1.3
1.1
—
—
—
0
0
209
1913
1.42
1.58
5.4
4.4
14.72
14.54
pmol/l
0.53
188
1774
15
78
1.98
1.57
2.5
3.3
285.60
156.44
mg/l
—
5
32
12
57
2.16
1.57
2.5
2.3
24.98
24.79
mmol/l
0.06
12
57
28
179
1.63
1.53
2.4
5.5
0.25
0.58
%
0.73
12
53
65
498
1.40
1.52
1.6
1.7
—
—
—
0
0
15
80
1.93
1.48
1.1
1.2
—
—
—
0
0
9
38
2.41
1.47
1.9
2.3
8.33
9.38
kpa
—
9
38
9
38
2.41
1.47
1.9
2.3
5.10
4.93
kpa
—
9
38
89
725
1.34
1.42
3.1
3.0
0.00
0.12
estimate
0.52
34
212
79
633
1.35
1.41
3.0
2.9
0.17
0.41
e6/l
1.47
63
456
56
426
1.40
1.37
2.3
2.6
519.46
545.30
mosm/kgh2o
0.38
48
367
11
54
2.08
1.35
1.0
1.1
3.05
5.82
u/ml
—
6
31
6
24
2.53
1.31
2.2
1.1
—
—
—
0
0
26
171
1.58
1.29
1.1
1.2
—
—
—
0
0
6
25
2.43
1.25
1.3
2.2
—
—
—
0
0
121
1045
1.29
1.24
2.2
1.9
1.32
1.35
mmol/l
0.22
100
901
8
38
2.14
1.19
1.8
1.7
—
—
—
0
0
23
150
1.58
1.19
3.6
2.3
190.12
5465.79
u/l
—
6
66
19
119
1.64
1.15
4.6
4.4
25.63
24.17
mmol/l
1.03
19
119
7
30
2.37
1.13
1.0
1.3
48.29
61.84
mmol/l
—
7
25
17
104
1.68
1.12
1.7
1.7
—
—
—
0
0
245
2347
1.51
1.09
6.3
5.2
2.77
2.78
mmol/l
0.05
229
2211
20
129
1.59
1.09
1.3
1.1
—
114.00
—
0
5
7
33
2.15
1.06
1.0
1.5
—
—
—
0
0
7
33
2.15
1.06
1.0
1.5
—
—
—
0
0
7
33
2.15
1.06
1.1
1.1
—
—
—
0
0
7
33
2.15
1.06
1.7
2.5
4.59
4.74
e9/l
—
7
33
7
33
2.15
1.06
1.0
1.5
—
—
—
0
0
7
33
2.15
1.06
1.0
1.5
—
—
—
0
0
7
33
2.15
1.06
2.1
1.5
4.36
6.21
u/ml
—
7
33
32
233
1.42
1.01
1.2
1.1
—
—
—
0
0
26
182
1.47
1.00
2.5
5.7
0.00
0.08
%
—
10
50
72
596
1.28
1.00
2.9
2.1
2.81
2.73
mg/l
0.14
61
514
76
634
1.28
1.00
2.1
1.7
21.90
20.87
nmol/l
0.25
58
544
124
1096
1.24
0.99
11.8
10.5
0.00
0.00
e9/l
0.77
105
888
27
192
1.45
0.97
1.6
1.4
—
—
—
0
0
100
865
1.25
0.97
3.9
3.7
37.15
65.54
e6/l
0.44
76
587
15
93
1.65
0.96
1.3
1.3
—
—
—
0
0
230
2192
1.35
0.92
4.9
3.9
1.29
1.26
mmol/l
0.23
213
2048
37
282
1.36
0.91
1.4
1.3
—
—
—
0
0
20
286
0.68
0.91
1.3
1.3
—
—
—
0
0
27
195
1.43
0.90
2.5
5.4
0.27
0.73
%
1.06
11
64
10
56
1.82
0.89
1.2
1.8
—
—
—
0
0
6
30
2.02
0.87
2.3
1.1
34.95
64.36
mu/l
—
6
25
18
121
1.52
0.85
1.2
1.4
164.13
253.78
miu/ml
—
8
61
6
31
1.96
0.85
1.3
1.2
—
—
—
0
0
6
32
1.89
0.82
1.0
1.1
—
5.66
—
0
11
8
47
1.72
0.81
1.6
2.3
55.38
59.27
%
—
8
47
12
74
1.65
0.79
1.4
1.1
—
—
—
0
0
23
166
1.42
0.78
4.2
3.3
1.22
1.23
mmol/l
0.11
23
142
59
492
1.26
0.78
6.5
5.2
1.93
2.42
ug/l
0.30
53
443
29
220
1.36
0.75
2.5
2.4
43.70
29.10
u/l
0.42
23
184
39
310
1.30
0.75
1.4
1.2
—
—
—
0
0
5
24
2.10
0.75
1.4
2.3
3.78
4.00
mmol/l
—
5
24
5
24
2.10
0.75
1.0
1.1
—
—
—
0
0
5
24
2.10
0.75
1.4
2.3
107.20
107.08
mmol/l
—
5
24
5
24
2.10
0.75
1.4
2.3
1.17
1.20
mmol/l
—
5
24
25
186
1.38
0.73
2.6
6.0
0.00
0.02
%
—
10
46
5
25
2.02
0.73
1.0
1.4
39.20
21.48
ng/l
—
5
25
241
2329
1.35
0.72
5.9
4.7
4.75
4.72
mmol/l
0.20
227
2195
240
2318
1.34
0.72
5.6
4.6
1.50
1.50
mmol/l
0.05
225
2176
5
26
1.94
0.71
1.0
1.2
—
—
—
0
0
82
716
1.21
0.71
5.1
6.4
—
—
—
0
0
233
2244
1.29
0.70
5.7
4.5
5.74
5.80
mmol/l
0.47
212
2091
81
708
1.21
0.69
2.7
2.9
—
0.13
—
0
15
16
111
1.47
0.67
1.4
1.1
0.82
0.87
g/l
0.63
16
111
7
43
1.64
0.67
1.1
1.2
—
—
—
0
0
29
225
1.32
0.66
1.6
1.8
3.58
3.39
mmol/l
0.49
20
167
5
29
1.74
0.64
1.0
1.1
—
—
—
0
0
16
113
1.44
0.62
20.0
1.5
—
—
—
0
0
6
35
1.73
0.58
1.0
1.1
—
—
—
0
0
50
425
1.22
0.57
3.0
3.3
224.45
261.56
ng/l
0.08
29
294
6
38
1.59
0.54
1.8
2.4
—
—
—
0
0
7
48
1.47
0.47
2.9
3.7
—
—
—
0
0
9
127
0.70
0.44
1.1
1.1
—
—
—
0
0
16
122
1.33
0.43
1.7
1.9
—
—
—
0
0
0
17
0.00
0.41
0.0
3.0
—
25.18
—
0
12
13
97
1.36
0.40
2.3
2.3
—
—
—
0
0
10
71
1.42
0.40
6.6
3.7
1.40
1.39
mg/l
—
10
64
13
98
1.34
0.38
25.9
1.8
—
—
—
0
0
10
72
1.40
0.37
33.1
1.7
—
—
—
0
0
25
209
1.22
0.35
1.5
1.2
72.22
171.71
u/ml
1.63
13
87
6
44
1.37
0.34
3.0
1.9
5.18
5.03
mmol/24h
—
6
38
11
82
1.36
0.34
1.5
1.4
—
—
—
0
0
28
238
1.20
0.34
1.6
1.5
—
—
—
0
0
6
45
1.34
0.34
5.8
2.7
8.32
8.32
kpa
—
6
45
7
56
1.26
0.29
1.4
5.1
68.81
59.45
%
—
7
56
7
57
1.23
0.29
1.0
1.1
—
—
—
0
0
7
57
1.23
0.29
1.0
1.1
—
—
—
0
0
25
214
1.19
0.29
1.2
1.5
—
—
—
0
0
15
123
1.23
0.26
1.7
1.4
0.22
0.22
mg/l
—
6
45
42
380
1.12
0.25
1.8
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
25.20
—
0
11
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
64.75
—
0
12
14
166
0.83
0.21
1.6
1.7
—
—
—
0
0
11
134
0.81
0.21
1.2
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
6.7
—
7.23
—
0
13
16
136
1.19
0.20
21.7
1.5
—
—
—
0
0
40
367
1.11
0.19
1.4
1.5
—
—
—
0
0
13
109
1.20
0.19
1.0
1.1
1.63
1.57
g/l
0.40
13
109
33
300
1.11
0.19
3.4
3.0
0.75
0.72
ug/l
0.09
25
180
16
142
1.13
0.13
21.7
1.5
—
—
—
0
0
16
143
1.13
0.12
21.7
1.5
—
—
—
0
0
16
144
1.12
0.10
21.4
1.5
—
—
—
0
0
16
145
1.11
0.09
3.0
2.5
48.00
54.25
u/ml
0.06
16
139
16
145
1.11
0.09
22.1
1.5
—
—
—
0
0
11
97
1.14
0.09
1.6
1.3
—
—
—
0
0
79
767
1.04
0.09
1.4
1.6
—
—
—
0
0
7
64
1.10
0.08
8.0
7.2
—
—
—
0
0
8
78
1.03
0.07
1.0
1.2
—
—
—
0
0
23
219
1.05
0.04
2.3
2.3
6.00
6.19
ph
0.42
13
142
36
348
1.04
0.04
3.0
2.9
4.53
3.10
e6/l
0.33
21
165
31
301
1.03
0.02
1.6
1.8
—
—
—
0
0
101
1006
1.01
0.00
3.2
2.9
—
—
—
0
0
11
105
1.05
0.00
1.0
1.1
—
0.46
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
2.96
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
64.40
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
11.40
—
0
5
0
7
0.00
-0.00
0.0
3.0
—
15.76
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
53.33
—
0
6
6
63
0.95
-0.00
1.2
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
25.50
—
0
6
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
75.56
—
0
9
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.8
—
52.22
—
0
9
5
59
0.84
-0.00
1.2
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.4
—
1.38
—
0
9
0
6
0.00
-0.00
0.0
3.7
—
47.33
—
0
6
0
9
0.00
-0.00
0.0
1.0
—
161.18
—
0
9
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
9.9
—
9.98
—
0
8
0
8
0.00
-0.00
0.0
1.3
—
27.00
—
0
8
0
6
0.00
-0.00
0.0
7.3
—
9.17
—
0
6

Mortality – FinRegistry

Association

Association between endpoint L12_HYPERTROPHICNAS and mortality.

Females

Parameter HR [95% CI] p-value
L12_HYPERTROPHICNAS 1.269 [0.91, 1.77] 0.16
Birth year 0.991 [0.98, 1.0] 0.048

During the follow-up period (1.1.1998 — 31.12.2019), 57 out of 816 females with L12_HYPERTROPHICNAS died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_HYPERTROPHICNAS.

N-year risk Females Males
1 0.101% No data
5 0.661% No data
10 1.736% No data
15 3.21% No data
20 5.77% No data

Relationships between endpoints

Index endpoint: L12_HYPERTROPHICNAS – Other and unspecified hypertrophic disorders of skin

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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