bone neoplasm: A benign, intermediate, or malignant neoplasm involving the bone or articular cartilage.
Benign neoplasm: Bone and articular cartilage, unspecified
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_BONE_CARTILAGE_NOS
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
313 |
4. Check minimum number of eventsNone |
313 |
5. Include endpointsNone |
313 |
6. Filter based on genotype QC (FinnGen only) |
278 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Bone and articular cartilage, unspecified
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of bone and articular cartilage
- Benign neoplasms
- Neoplasms
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2211 | 1137 | 1059 |
| Only index persons | 1934 | 1023 | 911 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.03 | 0.03 |
| Only index persons | 0.04 | 0.04 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 35.83 | 38.19 | 33.13 |
| Only index persons | 33.83 | 37.05 | 30.22 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 278 | 162 | 116 |
| Unadjusted period prevalence (%) | 0.06 | 0.06 | 0.05 |
| Median age at first event (years) | 40.35 | 40.07 | 40.75 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 292
- Matched controls
- 2920
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D16.90
ICD-10 Finland
Bone and articular cartilage, unspecified
+∞
209.5
175
*
21309
ICD-8 Finland
Benign neoplasm of bone and cartilage, Unspecified
+∞
51.6
48
*
21308
ICD-8 Finland
Benign neoplasm of bone and cartilage, Loco alio sive multiplici
+∞
38.4
36
*
2139X
ICD-9 Finland
Benign neoplasm of bone and articular cartilage, Bone and articular cartilage, site unspecified
+∞
22.2
21
*
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
18.8
19.1
29
17
D16.49
ICD-10 Finland
Bones of skull and face
+∞
13.6
13
*
NDR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of wrist or hand
19.4
13.6
20
11
AAP10
NOMESCO Finland
Extirpation of a skull lesion
146.5
13.6
14
*
9102
FHL
Trepanation or removal of the local bone process
24.1
11.7
16
7
D16.9
ICD-10 Finland
Benign neoplasm: Bone and articular cartilage, unspecified
+∞
9.4
9
*
D16.1
ICD-10 Finland
Benign neoplasm: Short bones of upper limb
38.0
9.1
11
*
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
16.9
8.6
13
8
D16.91
ICD-10 Finland
Benign tumor in unspecified localization in bone with urpsrung in teeth
+∞
8.4
8
*
D16.0
ICD-10 Finland
Benign neoplasm: Scapula and long bones of upper limb
46.2
7.8
9
*
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
41.0
6.8
8
*
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
27.3
6.3
8
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.5
6.1
41
181
R60.9
ICD-10 Finland
Oedema, unspecified
3.3
6.0
23
74
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
156
1195
1.66
4.32
6.3
7.4
1.22
1.21
mmol/l
0.39
136
1031
76
482
1.78
4.22
1.4
1.3
4.85
10.61
u/ml
0.67
30
192
137
1072
1.52
3.12
5.7
6.6
1.21
1.21
mmol/l
0.07
124
993
78
541
1.60
3.02
1.5
1.3
48.87
28.41
iu/ml
0.24
31
171
12
44
2.80
2.58
1.7
1.4
—
—
—
0
0
171
1440
1.45
2.50
5.6
5.3
6.57
6.56
mmol/l
0.02
160
1363
217
1917
1.51
2.46
9.4
7.9
76.82
78.63
u/l
0.31
208
1817
87
646
1.49
2.44
2.4
2.7
325.69
338.42
umol/l
0.63
78
577
42
265
1.68
2.34
5.7
6.7
—
—
—
0
0
221
1968
1.51
2.34
4.4
4.4
14.44
14.63
pmol/l
0.68
203
1817
215
1916
1.46
2.16
4.8
4.1
9.66
10.57
mm/h
0.49
203
1784
266
2489
1.77
2.09
16.3
14.7
20.29
21.87
mg/l
0.40
229
2011
267
2513
1.73
1.88
17.8
17.0
3.94
3.96
mmol/l
0.63
259
2460
46
318
1.53
1.79
7.9
7.1
104.65
104.23
mmol/l
0.28
46
318
266
2511
1.67
1.71
17.7
16.9
139.59
139.73
mmol/l
0.43
258
2464
97
779
1.37
1.70
1.8
2.1
261.24
213.27
u/l
0.25
91
740
126
1057
1.34
1.65
5.4
4.9
36.40
36.34
g/l
0.05
118
1009
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
11
50
2.25
1.59
2.5
2.3
0.23
0.31
iu/ml
—
6
24
249
2327
1.48
1.56
5.5
5.4
1.70
1.87
mu/l
1.90
233
2174
7
27
2.63
1.52
1.0
1.1
—
—
—
0
0
54
402
1.42
1.47
2.7
2.7
3.49
0.96
e6/l
0.52
29
204
152
1330
1.30
1.41
7.8
6.5
14.20
11.13
umol/l
0.79
144
1274
113
961
1.29
1.27
3.2
3.7
73.20
41.12
ng/l
0.30
75
635
28
189
1.53
1.24
1.7
2.5
79.42
67.76
ml/min/173m2
1.24
12
85
22
140
1.62
1.24
1.1
1.1
—
—
—
0
0
77
629
1.30
1.17
2.4
2.1
2.56
2.82
mg/l
0.31
71
557
0
35
0.00
1.16
0.0
1.5
—
—
—
0
0
0
35
0.00
1.16
0.0
1.5
—
—
—
0
0
0
36
0.00
1.14
0.0
1.4
—
—
—
0
0
83
687
1.29
1.14
2.9
3.0
0.31
0.44
e6/l
0.32
67
505
7
31
2.29
1.11
1.3
1.2
—
—
—
0
0
5
21
2.40
1.09
1.2
1.2
354.20
156.84
iu/ml
—
5
21
94
801
1.26
1.01
3.5
2.6
58.01
60.78
u/l
0.17
89
749
31
224
1.43
1.01
2.0
2.9
1.14
1.89
mmol/l
0.51
26
189
9
48
1.90
1.01
1.0
1.4
—
—
—
0
0
7
35
2.02
1.00
1.7
1.3
—
—
—
0
0
5
23
2.19
0.98
1.0
1.3
—
—
—
0
0
0
31
0.00
0.97
0.0
1.3
—
—
—
0
0
77
646
1.26
0.95
1.5
1.3
4.51
1.15
u/ml
0.45
23
171
12
70
1.74
0.94
1.1
1.1
—
—
—
0
0
12
70
1.74
0.94
1.7
2.4
—
—
—
0
0
99
856
1.24
0.93
3.3
3.3
2.34
2.35
mmol/l
0.20
91
798
12
71
1.72
0.90
1.1
1.1
—
—
—
0
0
60
492
1.28
0.89
2.6
2.7
2.43
2.45
mmol/l
0.52
54
443
72
605
1.25
0.87
1.5
1.7
0.69
1.19
mg/l
2.13
56
479
34
258
1.36
0.86
10.4
10.8
0.94
1.34
mmol/l
0.26
29
214
47
375
1.30
0.86
3.0
2.9
4.42
2.49
e6/l
0.69
22
177
13
81
1.63
0.82
1.0
1.1
—
2.75
—
0
11
6
32
1.89
0.82
3.0
2.1
14.00
13.22
%
—
6
32
196
1834
1.21
0.79
4.5
3.4
43.33
45.72
u/l
0.23
188
1748
0
26
0.00
0.79
0.0
1.1
—
—
—
0
0
71
604
1.23
0.77
2.8
2.3
—
—
—
0
0
39
308
1.31
0.77
3.1
5.5
1.04
1.01
mmol/l
0.38
39
283
5
24
2.10
0.75
1.6
1.2
147.20
109.42
pmol/l
—
5
24
89
778
1.21
0.74
3.7
4.1
3.55
8.87
mg/mmol
2.06
54
492
19
134
1.45
0.73
1.7
2.7
23.99
24.52
mmol/l
0.45
19
134
147
1349
1.18
0.71
3.5
3.7
0.00
0.00
estimate
0.50
33
279
70
603
1.21
0.68
3.9
3.8
1.02
1.02
kg/l
0.46
51
400
13
86
1.54
0.67
2.8
1.8
88.92
93.40
%
0.37
13
86
10
62
1.63
0.66
1.7
1.5
—
—
—
0
0
7
44
1.61
0.65
1.1
1.4
—
—
—
0
0
7
44
1.61
0.65
1.1
1.4
—
—
—
0
0
148
1367
1.17
0.64
3.6
3.7
0.03
0.00
estimate
0.49
34
285
278
2721
1.45
0.64
25.2
22.4
256.47
252.03
e9/l
0.51
273
2688
44
363
1.25
0.64
1.7
1.9
1.44
1.45
%
0.01
38
316
5
30
1.68
0.61
1.2
1.7
—
—
—
0
0
248
2395
1.24
0.61
4.8
4.9
5.83
5.89
mmol/l
0.25
230
2230
278
2723
1.44
0.61
25.1
22.3
4.55
4.52
e12/l
0.40
271
2682
0
23
0.00
0.58
0.0
1.6
—
—
—
0
0
0
23
0.00
0.58
0.0
1.6
—
—
—
0
0
0
23
0.00
0.58
0.0
1.6
—
—
—
0
0
148
1376
1.15
0.57
3.5
3.7
0.00
0.01
estimate
0.50
32
268
43
360
1.23
0.56
2.2
2.2
—
—
—
0
0
248
2403
1.21
0.53
14.8
13.8
84.91
84.09
ml/min/173m2
0.28
226
2209
115
1055
1.15
0.52
3.4
3.5
0.00
0.02
estimate
1.08
29
246
46
391
1.21
0.52
1.5
2.0
—
—
—
0
0
85
763
1.16
0.52
3.5
3.8
0.00
0.01
estimate
0.80
30
268
53
609
0.84
0.51
5.0
4.3
17.10
22.24
%
2.32
28
282
13
93
1.42
0.49
1.5
1.4
—
—
—
0
0
19
146
1.32
0.48
2.7
4.1
181.05
136.02
ng/l
0.45
19
134
7
48
1.47
0.47
2.4
3.5
13.00
36.24
u/ml
—
7
48
39
330
1.21
0.47
2.1
2.1
—
—
—
0
0
7
49
1.44
0.46
1.4
1.3
397.97
16.36
u/l
—
7
43
11
77
1.45
0.46
1.5
1.2
—
—
—
0
0
177
1684
1.13
0.44
3.3
3.4
—
—
—
0
0
35
295
1.21
0.44
1.5
2.0
—
—
—
0
0
17
131
1.32
0.43
1.1
1.3
—
—
—
0
0
51
447
1.17
0.43
1.4
1.6
—
—
—
0
0
115
1068
1.13
0.42
2.1
2.0
1.26
1.39
mmol/l
1.34
94
913
8
57
1.41
0.42
1.9
1.2
—
—
—
0
0
5
32
1.57
0.42
1.2
1.1
—
—
—
0
0
5
33
1.52
0.41
1.8
2.2
11.00
11.24
mmol/l
—
5
33
0
15
0.00
0.41
0.0
1.9
—
—
—
0
0
0
15
0.00
0.41
0.0
3.8
—
185.20
—
0
15
11
79
1.41
0.41
1.1
1.1
—
4.67
—
0
15
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
33
279
1.21
0.41
1.5
2.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
2.0
—
3.20
—
0
10
26
215
1.23
0.39
1.3
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
1.13
—
0
12
155
1471
1.11
0.39
10.9
9.7
4.19
4.07
e9/l
0.24
132
1286
121
1133
1.12
0.38
2.6
2.5
74.84
75.10
nmol/l
0.04
111
1032
75
683
1.13
0.38
2.2
3.3
480.48
1086.54
ng/l
3.08
60
569
18
143
1.28
0.38
2.1
3.0
131.94
132.07
g/l
0.01
18
137
20
162
1.25
0.36
1.6
1.5
—
—
—
0
0
44
387
1.16
0.36
1.4
1.6
1089.19
1217.43
nmol/l
0.52
35
294
9
122
0.73
0.36
2.0
1.4
—
—
—
0
0
20
163
1.24
0.35
2.4
2.0
—
—
—
0
0
10
73
1.38
0.35
1.5
2.0
3.62
5.83
iu/l
—
5
32
24
200
1.22
0.35
2.7
2.0
—
—
—
0
0
7
100
0.69
0.31
1.3
1.4
—
—
—
0
0
11
84
1.32
0.30
1.6
1.2
—
—
—
0
0
127
1205
1.10
0.30
3.2
2.8
—
—
estimate
—
0
0
131
1245
1.09
0.30
3.1
3.1
96.64
104.63
ug/l
0.33
125
1191
115
1088
1.09
0.29
2.2
2.0
99.18
97.29
pmol/l
0.13
61
570
8
64
1.26
0.27
1.1
1.2
—
—
—
0
0
12
95
1.27
0.26
1.2
1.6
—
—
—
0
0
85
798
1.09
0.25
2.6
3.0
0.00
0.01
estimate
0.74
27
234
256
2519
1.13
0.25
5.7
5.6
2.70
2.74
mmol/l
0.30
237
2362
9
77
1.17
0.24
1.1
1.8
—
—
—
0
0
36
323
1.13
0.24
2.0
2.0
3.29
3.48
ratio
0.59
28
261
28
247
1.15
0.23
4.0
4.4
6.00
8.14
ug/l
0.30
23
200
5
38
1.32
0.23
1.0
1.1
—
—
—
0
0
267
2636
1.15
0.23
13.6
11.3
26.73
25.77
u/l
0.39
259
2578
7
91
0.76
0.23
1.7
1.8
1.36
4.02
ug/l
—
7
82
253
2491
1.12
0.22
5.0
5.0
4.61
4.67
mmol/l
0.47
231
2344
5
41
1.22
0.22
3.0
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
1981.64
—
0
11
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
6
50
1.20
0.20
1.5
3.0
7.83
9.30
pmol/l
—
6
50
6
52
1.16
0.19
1.2
1.3
—
—
—
0
0
32
290
1.12
0.19
5.3
4.7
34.59
31.31
%
0.99
22
185
7
58
1.21
0.18
1.1
1.7
—
—
—
0
0
14
119
1.19
0.18
1.4
1.1
0.81
0.88
g/l
0.63
14
119
5
67
0.74
0.17
1.4
1.6
—
—
—
0
0
9
82
1.10
0.15
1.1
2.0
—
—
—
0
0
11
93
1.19
0.14
3.1
1.9
—
—
—
0
0
7
90
0.77
0.14
1.6
1.7
—
—
—
0
0
50
479
1.05
0.09
3.0
4.0
358.61
213.79
ng/l
0.22
38
369
7
68
1.03
0.08
1.1
1.2
—
—
—
0
0
6
71
0.84
0.07
1.7
1.3
—
—
—
0
0
6
70
0.85
0.07
1.5
1.2
—
64.90
—
0
12
236
2379
0.96
0.07
4.1
4.2
1.17
1.28
mmol/l
2.26
217
2218
7
81
0.86
0.07
2.4
1.9
214.00
235.71
pmol/l
—
7
75
55
532
1.04
0.07
1.5
1.6
—
—
—
0
0
11
102
1.08
0.03
3.9
3.1
46.27
1028.46
u/ml
1.34
11
87
25
258
0.97
0.02
3.1
3.2
—
—
—
0
0
13
132
0.98
0.00
1.5
1.4
0.06
0.33
mg/l
—
5
50
24
242
0.99
0.00
1.7
1.8
3.49
3.49
mmol/l
0.00
17
180
46
457
1.01
0.00
3.3
3.0
1.11
0.76
ug/l
0.27
31
272
72
724
0.99
0.00
1.6
1.6
20.25
21.25
nmol/l
0.25
62
615
12
116
1.04
0.00
1.1
1.1
1.43
1.57
g/l
0.87
12
116
248
2484
0.99
0.00
4.9
4.9
1.49
1.46
mmol/l
0.73
228
2325
235
2355
0.99
0.00
5.8
6.0
38.22
39.00
mmol/mol
0.78
223
2227
6
63
0.95
0.00
1.3
1.5
—
—
—
0
0
5
49
1.02
-0.00
1.4
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
50
1.00
-0.00
1.0
1.1
0.88
0.95
nmol/l
—
5
45
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
69
1.01
-0.00
1.4
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
13
130
1.00
-0.00
1.3
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
7
70
1.00
-0.00
1.4
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
1.18
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.2
—
29.94
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_BONE_CARTILAGE_NOS and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_BONE_CARTILAGE_NOS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_BONE_CARTILAGE_NOS – Benign neoplasm: Bone and articular cartilage, unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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