Abscess of mediastinum

J10_ABSCMEDIASTINUM

Lung Abscess: Solitary or multiple collections of PUS within the lung parenchyma as a result of infection by bacteria, protozoa, or other agents.

Suggest a new description

Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — J85.3 Hospital discharge: ICD-9 — 5131 Cause of death: ICD-10 — J85.3 Cause of death: ICD-9 — 5131 2 out of 7 registries used, show all original rules.	73
4. Check minimum number of events None	73
5. Include endpoints None	73
6. Filter based on genotype QC (FinnGen only)	65

Control definitions (FinnGen only)

Control exclude: J10_NECROTIC

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: J85
Name in latin: Abscessus mediastini

NAME	J10_ABSCMEDIASTINUM
CONTROL_EXCLUDE	J10_NECROTIC
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	J853
HD_ICD_9	5131
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	J853
COD_ICD_9	5131
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Abscess of mediastinum based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	468	143	320
Only index persons	353	110	243
Unadjusted period prevalence (%)
Whole population	0.01	0.00	0.01
Only index persons	0.01	0.00	0.01
Median age at first event (years)
Whole population	62.93	66.74	61.28
Only index persons	61.87	64.58	60.65

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	65	23	42
Unadjusted period prevalence (%)	0.02	0.01	0.02
Median age at first event (years)	65.62	61.68	67.77

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
67: Matched controls
670

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

J85.3

ICD-10 Finland

Abscess of mediastinum

+∞

86.3

T81.4

ICD-10 Finland

Infection following a procedure, not elsewhere classified

12.7

13.0

ZXD05

NOMESCO Finland

Urgent procedure

6.0

12.2

127

GD1UA

NOMESCO Finland

Thorax X-ray examination outside radiological department

5.4

10.3

ENA32

NOMESCO Finland

Incision of deep pharyngeal infection

+∞

9.6

FWC00

NOMESCO Finland

Reoperation for deep infection in surgery of heart and major thoracic vessels

+∞

9.6

J98.5

ICD-10 Finland

Diseases of mediastinum, not elsewhere classified

57.8

8.9

TPH15

NOMESCO Finland

Insertion of central venous catheter through external or internal jugular vein

9.0

8.5

N17.9

ICD-10 Finland

Acute renal failure, unspecified

14.3

7.4

TQW11

NOMESCO Finland

Vacuum treatment of wound

34.1

7.3

TPH20

NOMESCO Finland

Insertion of central venous catheter through subclavian or brachiocephalic vein

44.7

6.9

ZXE20

NOMESCO Finland

More than three and less than five hours

4.6

6.8

J01MA12

ATC

levofloxacin; systemic

4.1

6.7

GBB00

NOMESCO Finland

Tracheostomy

76.9

6.5

J39.0

ICD-10 Finland

Retropharyngeal and parapharyngeal abscess

76.9

6.5

FM1BE

NOMESCO Finland

Cardiac ultrasound examination through oesophagus

6.9

6.5

K22.3

ICD-10 Finland

Perforation of oesophagus

+∞

6.3

GD1BD

NOMESCO Finland

Thorax extensive CT-examination

7.7

6.3

J01FF01

ATC

clindamycin; systemic

3.7

6.1

109

FNA01

NOMESCO Finland

Anastomosis to coronary artery from internal mammary artery, one distal anastamosis

7.4

6.1

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3042936) Bacteria identified in Isolate by Culture

4.68

8.16

6.4

2.0

—

(3023368) Bacteria identified in Blood by Culture

181

4.00

7.24

10.4

5.3

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

5.08

6.84

2.1

1.4

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

10.95

6.61

2.2

1.8

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

3.84

6.28

16.5

6.0

1.18

1.10

mmol/l

0.37

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

126

3.50

5.81

8.6

2.5

—

(3019977) pH of Arterial blood

3.75

5.69

46.2

7.7

7.42

7.41

—

(3003396) Base excess in Arterial blood by calculation

3.70

5.58

45.9

7.6

0.52

1.26

mmol/l

0.33

(3000991) Gas panel - Venous blood

4.02

5.56

60.3

9.0

—

(3019230) Fractional oxyhemoglobin in Venous blood

10.44

5.50

4.9

1.1

64.10

60.15

—

(3044640) Blood type and Crossmatch panel - Blood

179

3.00

4.66

9.3

2.6

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

3.82

4.37

2.4

1.9

1.95

1.52

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

4.94

4.30

4.2

2.6

1.05

1.35

0.45

(3014111) Lactate [Moles/volume] in Serum or Plasma

3.52

4.27

63.1

7.6

0.97

1.35

mmol/l

1.31

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

4.78

4.18

4.2

2.6

0.69

0.00

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

3.44

3.95

2.7

2.6

6.39

6.29

ug/l

0.01

(3000494) Fungus identified in Specimen by Culture

3.15

3.76

2.5

1.5

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

232

2.63

3.64

8.4

3.0

—

estimate

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

6.32

3.45

1.4

1.2

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

6.32

3.45

1.4

1.2

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

5.29

3.37

1.6

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

3.95

3.31

1.8

1.7

—

(3012544) pH of Venous blood

2.96

3.28

7.4

3.8

7.37

7.38

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

3.34

3.23

10.1

3.9

23.38

23.81

mmol/l

0.21

(3017143) Hepatitis C virus Ab [Presence] in Serum

3.04

3.13

1.5

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

8.09

3.12

1.7

1.0

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

6.37

3.10

1.6

1.2

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

2.82

3.02

1.9

1.5

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

10.65

3.02

1.4

1.0

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

115

2.52

2.97

2.2

1.9

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.70

2.79

3.1

1.8

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

8.87

2.79

1.8

1.2

—

(4268621) Lupus anticoagulant assay

8.87

2.79

1.6

1.5

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

8.87

2.79

1.8

1.2

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

4.63

2.77

2.1

1.1

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

6.46

2.76

1.2

1.1

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

6.46

2.76

1.2

1.1

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

3.10

2.71

7.0

1.9

204.25

224.72

ng/l

0.08

(42529406) Shigella sp [Presence] in Stool by Culture

5.87

2.60

1.2

1.1

—

(3005570) Glucose [Moles/volume] in Urine

7.60

2.59

1.0

2.6

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.79

2.57

77.6

10.1

25.54

25.10

mmol/l

0.18

(3005719) IgG [Mass/volume] in Serum or Plasma

2.80

2.45

3.1

2.7

9.92

10.56

g/l

0.25

(42870588) Differential panel, method unspecified - Blood

218

2.14

2.37

18.4

5.4

—

(3028026) IgM [Mass/volume] in Serum or Plasma

2.83

2.34

1.8

1.6

0.81

0.98

g/l

0.49

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

3.64

2.26

1.9

2.0

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

5.90

2.25

1.4

1.9

—

(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

5.90

2.25

9.6

1.4

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

2.31

2.23

2.7

2.53

0.56

e6/l

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

3.99

2.21

1.1

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

4.59

2.20

1.3

1.1

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.34

2.14

2.4

1.8

—

(3001334) Neutrophil cytoplasmic Ab [Units/volume] in Serum

3.60

2.02

1.0

1.1

—

(3003327) Ova and parasites identified in Stool by Light microscopy

4.81

1.97

1.6

1.0

—

(3032080) INR in Blood by Coagulation assay

287

1.98

1.93

28.8

16.1

1.40

1.28

inr

0.48

240

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

3.27

1.85

1.9

1.8

—

(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma

3.27

1.85

3.1

2.2

33.71

35.42

u/l

—

(40768797) Stomach Pathology biopsy report

2.22

1.84

1.4

1.3

—

(3044941) Cell count panel - Synovial fluid

4.06

1.74

1.0

1.2

—

(4035726) Immunohistochemistry procedure

2.39

1.73

2.1

1.3

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

3.36

1.70

1.3

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

3.77

1.64

1.2

1.3

—

(3025941) Bacteria identified in Stool by Culture

2.88

1.63

1.4

1.2

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

298

1.85

1.62

20.9

8.6

1.19

1.21

mmol/l

0.64

253

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

3.51

1.55

1.0

1.1

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

2.13

1.53

18.1

4.1

6.26

10.51

umol/l

0.66

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.02

1.49

2.4

1.7

—

(36660697) Celiac disease serology panel - Serum

2.38

1.48

1.4

1.3

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

2.89

1.47

2.0

1.5

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

3.29

1.46

1.8

1.3

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

2.57

1.43

2.0

1.5

0.61

0.22

mg/l

—

(3022313) Gas panel - Capillary blood

2.33

1.42

10.8

7.0

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

125

1.86

1.38

11.8

2.1

1.89

1.66

mg/l

0.14

103

(3037522) Nuclear Ab [Titer] in Serum

2.03

1.38

1.4

1.3

720.00

302.50

titre

—

(3007164) IgA [Mass/volume] in Serum or Plasma

142

1.82

1.37

1.8

1.5

2.82

2.76

g/l

0.03

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

2.64

1.33

1.0

1.3

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

2.91

1.31

1.4

1.1

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

2.91

1.31

1.0

1.2

—

(1761868) Lipid panel - Serum or Plasma

202

0.51

1.30

2.4

3.5

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.38

1.29

1.8

1.6

—

(3030467) Casts [#/volume] in Urine by Automated count

172

1.72

1.25

3.6

3.0

0.41

0.40

e6/l

0.00

125

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

2.43

1.21

1.2

1.3

—

(3018095) Leukocytes [#/volume] in Urine

228

1.67

1.21

4.7

4.3

60.44

76.25

e6/l

0.13

164

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.81

1.08

2.9

0.80

2.41

e6/l

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

2.04

1.08

16.5

3.9

31.10

29.89

u/l

—

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

1.83

1.00

22.2

4.7

305.08

252.93

u/l

0.59

(3037467) Urinalysis macro (dipstick) panel - Urine

365

1.60

0.99

6.7

4.5

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.34

0.96

2.5

2.4

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

175

1.58

0.93

3.7

2.2

155.88

157.05

u/l

0.01

168

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.89

0.89

11.6

11.0

—

(3000492) Spirometry study

1.85

0.85

2.4

1.5

—

(3019060) Gas panel - Arterial blood

1.76

0.82

4.8

3.4

—

(46236952) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)/1.73 sq M

1.90

0.81

1.3

3.5

—

57.31

—

(3006184) Hemoglobin [Mass/volume] in Capillary blood

0.00

0.79

0.0

2.6

—

124.45

—

(3015736) pH of Urine

238

1.47

0.77

7.0

3.8

6.35

6.15

0.43

124

(3020891) Body temperature

1.94

0.76

5.3

4.8

37.11

36.96

°c

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.66

0.76

2.1

1.5

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

278

1.45

0.74

18.9

5.2

32.12

35.19

g/l

2.06

262

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

393

1.44

0.65

4.4

3.8

15.09

14.77

pmol/l

0.33

357

(3002582) Erythrocytes [#/volume] in Urine

206

1.43

0.65

3.8

3.5

132.45

342.56

e6/l

0.28

158

(3018418) pH of Serum or Plasma

178

1.44

0.65

8.8

5.1

7.42

7.40

1.41

126

(40767503) Oxygen content in Capillary blood by calculation

0.00

0.61

0.0

3.3

—

16.36

—

(3023351) European house dust mite IgE Ab [Units/volume] in Serum

0.00

0.61

0.0

1.2

—

0.71

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

1.55

0.61

1.2

49.76

44.17

iu/ml

—

(4034850) Laboratory test

0.00

0.59

0.0

20.0

—

(3022145) Colonoscopy Study observation

1.55

0.57

1.6

1.4

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

419

1.41

0.57

27.6

9.1

105.70

86.47

u/l

1.25

400

(3035350) Ketones [Presence] in Urine by Test strip

298

1.37

0.56

6.7

4.3

0.00

23.20

estimate

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

202

1.38

0.55

5.7

3.2

2.26

2.36

mmol/l

1.98

184

(3003694) ABO and Rh group [Type] in Blood

129

1.43

0.52

2.4

1.4

—

(3026008) Bacteria identified in Urine by Culture

159

1.37

0.48

4.2

3.0

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

246

1.32

0.45

3.0

2.2

102.37

94.70

pmol/l

0.50

136

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

201

0.73

0.44

3.5

4.3

19.04

22.33

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.56

0.42

1.0

1.1

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.42

0.0

1.3

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.41

0.0

1.0

—

1.47

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.51

0.41

1.2

1.3

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.41

0.0

1.1

—

0.98

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

1.46

0.39

11.5

5.8

5.07

5.09

kpa

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

309

1.28

0.39

3.0

2.9

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

223

1.27

0.36

4.9

3.5

—

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

1.40

0.35

5.7

4.1

160.33

68.26

ng/l

—

(3002256) Pathology report gross observation

1.41

0.34

1.5

1.3

—

(3021601) Nitrite [Presence] in Urine by Test strip

294

1.24

0.32

7.0

4.3

0.00

estimate

—

(40761511) CBC panel - Blood by Automated count

539

0.77

0.31

39.2

16.4

—

(3031040) Bacteria [#/volume] in Urine by Automated count

359

1.21

0.26

7.5

4.7

—

394.30

—

(3024731) MCV [Entitic mean volume] in Red Blood Cells

564

0.78

0.25

79.8

27.6

91.10

90.92

0.10

557

(3000963) Hemoglobin [Mass/volume] in Blood

564

0.78

0.25

80.7

27.9

121.28

134.15

g/l

5.75

556

(3009542) Hematocrit [Volume Fraction] of Blood by calculation

564

0.78

0.25

99.6

28.3

36.63

40.23

5.27

556

(3035941) MCH [Entitic mass]

564

0.78

0.25

79.7

27.6

29.99

30.28

0.63

557

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

1.38

0.24

1.6

3.4

39.50

55.74

—

(40761535) Cells panel - Urine sediment

1.34

0.24

8.2

3.3

—

(3045414) Leukocytes [Presence] in Urine

1.27

0.23

1.8

2.4

—

0.00

estimate

—

(40768793) Breast Pathology biopsy report

0.00

0.21

0.0

1.5

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.21

0.0

1.4

—

91.60

—

(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(40768804) Tissue Pathology biopsy report

205

1.19

0.21

3.6

2.1

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

0.20

0.0

1.4

—

(40768800) Prostate Pathology biopsy report

0.00

0.20

0.0

1.1

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.19

0.20

2.3

3.8

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

0.71

0.18

2.0

1.8

449.80

364.77

nmol/l

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.22

0.17

4.6

4.1

—

(40758558) Short blood count panel - Blood

190

1.15

0.15

22.0

6.8

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

250

1.13

0.14

4.5

4.4

40.99

50.83

ng/l

0.18

193

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

257

0.90

0.11

4.2

5.4

1.51

2.97

ug/l

0.60

227

(3028626) Oxygen [Partial pressure] in Capillary blood

1.15

0.10

19.0

7.0

7.78

8.79

kpa

—

(40761536) Microorganisms panel - Urine sediment

1.09

0.10

3.2

4.0

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

1.06

0.09

1.5

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.16

0.08

1.1

1.7

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

543

0.89

0.08

35.4

13.2

25.85

26.45

u/l

0.12

532

(3029937) Albumin [Presence] in Urine by Test strip

172

0.91

0.06

11.1

4.6

0.00

estimate

—

(3013512) EKG study

190

0.93

0.04

4.7

4.2

—

(3012516) Albumin [Mass/volume] in Urine

190

0.93

0.04

3.1

3.3

67.94

73.45

mg/l

0.03

133

(3020564) Creatinine [Moles/volume] in Serum or Plasma

549

0.92

0.04

66.2

24.3

83.13

82.57

umol/l

0.03

543

(40760892) CBC W Ordered Manual Differential panel - Blood

134

1.06

0.01

6.6

6.0

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

538

1.02

0.00

79.1

22.5

3.97

4.02

mmol/l

0.58

529

(3019550) Sodium [Moles/volume] in Serum or Plasma

537

1.03

0.00

77.2

22.5

138.76

139.60

mmol/l

1.55

528

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

223

0.98

0.00

7.9

4.3

0.00

estimate

—

(3020682) Albumin/Creatinine [Ratio] in Urine

195

1.04

0.00

3.9

4.1

23.45

12.00

mg/mmol

0.36

134

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.0

1.3

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.0

1.6

—

1008.14

—

(3004451) EKG impression Narrative

0.00

0.0

1.3

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

0.0

1.3

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.0

1.3

—

(4146454) Self-monitoring of blood glucose

0.00

-0.00

0.0

1.7

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.0

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

(37208534) Antinuclear antibody arbitrary concentration in serum

0.00

-0.00

0.0

1.0

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

6.0

—

26.45

—

(3012494) Peanut IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.5

—

1.89

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.5

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

-0.00

0.0

1.3

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

80.44

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.1

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

-0.00

0.0

1.6

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.5

—

(3012565) Volume of 24 hour Urine

0.00

-0.00

0.0

2.4

—

1727.86

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

44.84

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.5

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3003191) Choriogonadotropin [Presence] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

(42529215) Follitropin [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

1.5

—

26.17

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.5

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

-0.00

0.0

1.6

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

-0.00

0.0

1.0

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(40759850) Jo-1 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.5

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.5

—

(3018333) Ribosomal P Ab [Presence] in Serum

0.00

-0.00

0.0

1.5

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint J10_ABSCMEDIASTINUM and mortality.

Females

No data

Males

Parameter	HR [95% CI]	p-value
J10_ABSCMEDIASTINUM	2.669 [1.97, 3.61]	< 0.001
Birth year	0.985 [0.98, 0.99]	0.001

During the follow-up period (1.1.1998 — 31.12.2019), 119 out of 240 males with J10_ABSCMEDIASTINUM died.

Mortality risk

Mortality risk for people of age

years, who have J10_ABSCMEDIASTINUM.

N-year risk	Females	Males
1	No data	0.478%
5	No data	3.176%
10	No data	7.433%
15	No data	13.659%
20	No data	21.813%

Relationships between endpoints

↥

Index endpoint: J10_ABSCMEDIASTINUM – Abscess of mediastinum

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Abscess of mediastinum

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints