Risteys · AB1_NOCARDIOSIS

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — A43 Cause of death: ICD-10 — A43 2 out of 7 registries used, show all original rules.	42
4. Check minimum number of events None	42
5. Include endpoints None	42
6. Filter based on genotype QC (FinnGen only)	35

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	241	107	132
Only index persons	196	83	113
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	62.77	64.15	61.68
Only index persons	60.79	59.96	61.40

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	35	14	21
Unadjusted period prevalence (%)	0.01	0.00	0.01
Median age at first event (years)	63.42	60.45	65.40

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

26.24

7.59

1.1

1.0

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

26.24

7.59

1.7

1.0

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

18.63

7.43

2.4

1.4

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

21.85

7.20

1.2

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

22.83

6.62

1.8

1.0

—

(3026250) Tacrolimus [Mass/volume] in Blood

+∞

6.41

49.7

0.0

7.22

—

ug/l

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

5.68

6.41

4.1

1.7

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

12.33

6.29

3.4

1.4

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

13.03

5.95

7.0

1.7

94.90

99.80

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

10.53

5.83

7.8

3.7

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

5.54

5.76

2.3

1.6

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

11.83

5.69

1.5

1.4

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

11.83

5.69

3.9

1.5

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

14.22

5.63

3.0

1.4

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

5.39

5.58

2.9

1.7

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

16.36

5.34

1.4

1.3

—

(3042733) HLA Ab [Presence] in Serum

+∞

5.32

2.2

0.0

—

(3024471) HLA-A [Type]

+∞

5.32

1.0

0.0

—

(3024932) HLA-DR beta [Type]

+∞

5.32

1.2

0.0

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

11.34

5.10

1.6

1.4

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

5.66

4.94

21.7

4.7

1.05

1.07

mmol/l

0.11

(4195642) Thrombophilia screening test

16.66

4.77

1.3

1.2

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

16.66

4.77

4.6

1.4

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

6.50

4.68

2.0

1.5

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

4.40

4.63

2.7

2.1

—

(3042936) Bacteria identified in Isolate by Culture

5.54

4.63

5.7

1.7

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

6.58

4.42

26.5

6.6

1.24

1.02

0.26

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

6.58

4.42

27.2

6.6

0.74

0.69

0.12

(3000494) Fungus identified in Specimen by Culture

4.45

4.29

3.9

1.5

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

11.87

4.20

2.6

1.0

—

(3012544) pH of Venous blood

6.00

4.14

20.5

3.7

7.36

7.40

—

(3023368) Bacteria identified in Blood by Culture

3.87

4.05

13.4

3.4

—

(3022948) Iron [Moles/volume] in Serum or Plasma

4.02

3.90

9.7

1.9

12.63

12.87

umol/l

0.04

(3017143) Hepatitis C virus Ab [Presence] in Serum

4.79

3.90

2.1

1.4

—

(44790049) Parainfluenza type 3 nucleic acid detection

13.86

3.90

3.2

1.8

—

(44806118) Parainfluenza type 4 nucleic acid detection

13.86

3.90

3.2

1.8

—

(44790048) Parainfluenza type 2 nucleic acid detection

13.86

3.90

3.2

1.8

—

(44790047) Parainfluenza type 1 nucleic acid detection

13.86

3.90

3.2

1.8

—

(3000991) Gas panel - Venous blood

5.51

3.89

42.1

7.5

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

6.06

3.88

30.0

6.4

23.70

25.03

mmol/l

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

6.57

3.78

16.7

3.8

24.27

25.01

mmol/l

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

5.29

3.77

2.0

1.5

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

3.94

3.66

10.1

1.9

20.94

20.78

0.02

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

4.52

3.51

5.8

2.1

18.33

7.93

umol/l

0.29

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

3.48

3.41

7.1

2.1

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

9.88

3.39

1.8

1.3

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

9.88

3.39

3.0

1.3

—

(4035726) Immunohistochemistry procedure

5.04

3.38

3.2

1.3

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

3.68

3.33

10.0

1.8

2.36

g/l

0.00

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

3.78

3.31

2.4

1.5

—

(3005895) Myoglobin [Mass/volume] in Serum or Plasma

8.63

3.18

10.3

1.4

306.17

138.63

ug/l

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

138

3.37

3.14

14.8

3.5

33.29

36.16

g/l

1.71

132

(3004809) Band form neutrophils/Leukocytes in Blood

11.22

3.06

9.4

3.0

1.80

0.80

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

3.90

3.06

37.3

5.1

106.25

103.50

mmol/l

1.12

(3012110) Lysozyme [Mass/volume] in Serum or Plasma

7.65

2.98

4.3

1.3

12.63

10.90

mg/l

—

(3044640) Blood type and Crossmatch panel - Blood

108

3.11

2.91

6.2

2.0

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

4.38

2.79

43.7

6.2

1.11

1.10

mmol/l

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

147

3.05

2.66

6.3

2.4

—

estimate

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

4.53

2.63

28.1

4.0

24.88

25.34

mmol/l

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

7.99

2.63

1.2

1.1

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

7.99

2.63

1.8

1.1

—

(42870588) Differential panel, method unspecified - Blood

107

2.83

2.49

36.3

5.5

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

6.98

2.45

1.2

1.5

—

(3000093) Morphology [Interpretation] in Blood Narrative

6.98

2.45

1.0

—

(3012336) Haptoglobin [Mass/volume] in Serum or Plasma

4.51

2.38

2.6

1.87

1.68

g/l

—

(3046279) Procalcitonin [Mass/volume] in Serum or Plasma

6.19

2.28

2.8

1.7

0.16

0.31

ug/l

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

4.04

2.17

2.1

1.5

—

(3007853) Bacteria identified in Skin by Aerobe culture

3.25

2.10

2.9

1.6

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

4.24

2.02

3.3

1.3

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

5.05

2.00

17.8

2.9

0.50

0.63

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

5.05

2.00

1.4

1.3

—

(3004588) Protein electrophoresis panel - Serum or Plasma

3.34

2.00

2.0

3.0

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

311

0.38

1.95

6.7

5.2

4.46

4.48

mmol/l

0.04

291

(3001334) Neutrophil cytoplasmic Ab [Units/volume] in Serum

3.98

1.92

3.3

1.2

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

310

0.39

1.89

6.8

5.0

1.33

1.42

mmol/l

0.64

288

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

4.62

1.88

17.8

2.8

0.68

2.27

—

(40768443) Skin Pathology biopsy report

4.62

1.88

1.6

1.1

—

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

4.62

1.88

1.6

1.3

—

394.69

miu/ml

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

317

0.38

1.86

7.8

6.1

2.63

2.58

mmol/l

0.09

295

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

2.67

1.85

7.4

2.8

0.43

2.22

e6/l

—

(1761868) Lipid panel - Serum or Plasma

120

0.33

1.79

2.2

3.0

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

3.94

1.67

2.6

1.5

0.00

g/l

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

142

2.30

1.66

38.1

5.7

1.20

1.21

mmol/l

0.17

130

(3001122) Ferritin [Mass/volume] in Serum or Plasma

135

2.24

1.58

9.7

2.7

288.54

112.47

ug/l

1.05

128

(3026493) Urate [Moles/volume] in Serum or Plasma

100

2.27

1.58

5.8

2.9

361.29

356.31

umol/l

0.08

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

3.43

1.49

1.0

—

(3019832) Treponema pallidum Ab [Presence] in Serum

2.72

1.47

1.4

2.3

—

(3010813) Leukocytes [#/volume] in Blood

338

0.40

1.46

112.0

22.6

6.98

6.59

e9/l

0.45

332

(3026361) Erythrocytes [#/volume] in Blood

338

0.40

1.46

112.0

22.6

4.15

4.55

e12/l

3.09

332

(3007461) Platelets [#/volume] in Blood

338

0.40

1.46

112.1

22.7

252.93

239.65

e9/l

0.36

333

(3009343) pH of Capillary blood

2.90

1.43

3.0

3.2

7.40

7.42

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

2.32

1.42

7.5

2.7

0.46

1.37

e6/l

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

104

2.15

1.41

9.6

2.7

35.76

29.41

u/l

0.36

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

2.77

1.36

3.2

5.27

4.96

kpa

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

2.12

1.34

9.7

2.6

63.56

107.40

u/l

0.45

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

299

0.46

1.32

5.6

4.1

1.40

1.29

mmol/l

0.52

275

(40764999) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M

312

0.47

1.17

77.0

14.4

73.24

80.00

ml/min/173m2

0.54

286

(3002256) Pathology report gross observation

2.25

1.14

2.4

1.2

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

139

1.93

1.11

4.1

2.4

69.69

78.26

nmol/l

1.16

126

(3018418) pH of Serum or Plasma

103

1.96

1.11

18.1

4.4

7.39

0.06

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

331

0.48

1.08

52.7

11.5

26.83

27.02

u/l

0.02

325

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

171

1.87

1.01

35.3

5.7

10.26

13.53

umol/l

0.70

160

(3022145) Colonoscopy Study observation

2.09

1.00

1.3

1.4

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

2.09

1.00

1.7

1.4

—

(3003694) ABO and Rh group [Type] in Blood

1.92

0.97

1.6

1.3

—

(3000492) Spirometry study

2.35

0.96

5.5

1.6

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.98

0.91

1.5

1.4

—

(3019225) pH of Specimen

2.11

0.89

19.7

4.1

7.25

7.35

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

305

0.53

0.88

7.0

5.2

6.87

5.95

mmol/l

0.88

280

(40758558) Short blood count panel - Blood

110

1.79

0.87

36.0

6.5

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

149

1.72

0.82

2.5

2.0

80.44

96.62

pmol/l

0.86

(3019309) Folate [Moles/volume] in Red Blood Cells

1.83

0.81

1.8

1.5

594.43

1262.16

nmol/l

—

(3022096) Basophils/Leukocytes in Blood

150

1.70

0.79

40.8

5.9

0.57

0.66

0.36

143

(40761511) CBC panel - Blood by Automated count

319

0.54

0.78

53.1

12.7

—

(3006504) Eosinophils/Leukocytes in Blood

152

1.67

0.74

40.9

5.9

2.06

2.81

0.65

146

(3019069) Monocytes/Leukocytes in Blood

154

1.63

0.69

41.0

5.9

10.47

8.91

0.47

149

(3015377) Calcium [Moles/volume] in Serum or Plasma

108

1.64

0.67

5.3

2.8

2.36

mmol/l

0.02

101

(3018010) Neutrophils/Leukocytes in Blood

156

1.60

0.64

37.6

5.9

60.34

58.32

0.27

150

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

298

0.60

0.64

11.7

5.8

43.56

39.53

mmol/mol

0.72

274

(40768797) Stomach Pathology biopsy report

1.64

0.63

1.1

1.3

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

321

0.59

0.61

102.8

16.9

4.10

4.00

mmol/l

0.95

315

(3019550) Sodium [Moles/volume] in Serum or Plasma

320

0.60

101.8

16.8

138.69

139.65

mmol/l

1.49

315

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

1.56

0.58

2.3

1.9

422.78

463.96

pmol/l

—

(40768804) Tissue Pathology biopsy report

131

1.54

0.56

4.5

2.1

—

(3013115) Eosinophils [#/volume] in Blood

171

1.51

0.53

39.7

6.0

0.18

0.20

e9/l

0.12

152

(3003338) MCHC [Entitic Mass/volume] in Red Blood Cells

264

0.67

0.47

107.3

18.5

328.65

332.42

g/l

1.14

264

(3013707) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method

245

0.68

0.46

20.6

4.5

17.62

12.98

mm/h

0.56

230

(3045414) Leukocytes [Presence] in Urine

1.70

0.45

2.0

—

0.00

estimate

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

0.00

0.42

0.0

1.1

—

64.22

—

(4024509) Urine culture

0.00

0.41

0.0

1.6

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

1.6

—

40.61

—

(3019198) Lymphocytes [#/volume] in Blood

167

1.42

0.41

36.4

6.3

1.47

1.76

e9/l

0.86

151

(3026008) Bacteria identified in Urine by Culture

100

1.46

0.41

5.0

2.4

—

(3015736) pH of Urine

133

1.35

0.31

5.7

3.3

5.80

6.20

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

196

1.29

0.25

3.6

2.6

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.40

0.25

2.2

3.6

—

(3044889) 12 lead EKG panel

232

0.79

0.22

10.4

4.1

—

(3027315) Oxygen [Partial pressure] in Blood

0.00

0.22

0.0

1.5

—

8.01

—

(3012501) Base excess in Blood by calculation

0.00

0.22

0.0

1.5

—

3.14

—

(3010421) pH of Blood

0.00

0.22

0.0

2.2

—

7.45

—

(3013290) Carbon dioxide [Partial pressure] in Blood

0.00

0.22

0.0

1.5

—

4.75

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.00

0.22

0.0

1.0

—

(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation

0.00

0.20

0.0

1.7

—

281.00

—

(3013512) EKG study

107

0.79

0.15

3.3

4.0

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

134

0.85

0.11

4.3

4.2

22.05

22.04

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

137

1.16

0.09

8.9

2.8

—

(3000850) Epithelial cells [#/volume] in Urine

0.89

0.07

9.0

2.3

4.16

6.12

e6/l

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

232

1.09

0.03

4.4

3.9

13.57

15.02

pmol/l

2.84

217

(36304419) Bacteria [Presence] in Urine

108

1.03

0.00

10.2

2.5

—

estimate

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

251

0.99

0.00

48.5

7.3

104.52

75.46

u/l

0.84

241

(3031040) Bacteria [#/volume] in Urine by Automated count

227

1.03

0.00

10.5

4.1

—

107.25

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

212

0.98

0.00

6.9

2.9

104.71

57.96

u/l

0.74

202

(3011985) Renin [Units/volume] in Plasma

0.00

-0.00

0.0

1.3

—

23.59

—

(40768793) Breast Pathology biopsy report

0.00

-0.00

0.0

1.4

—

(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

-0.00

0.0

1.4

—

87.06

—

(3016879) Cocaine [Presence] in Urine

0.00

-0.00

0.0

1.1

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

-0.00

0.0

1.2

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

-0.00

0.0

1.0

—

1.18

—

(3035715) Granulocytes [#/volume] in Blood

0.00

-0.00

0.0

2.9

—

4.39

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.7

—

2.77

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

0.73

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

61.90

—

(4281824) Cell count and differential, peritoneal fluid

0.00

-0.00

0.0

1.0

—

(3016921) Smith extractable nuclear Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.6

—

(3028300) Cannabinoids [Presence] in Urine

0.00

-0.00

0.0

1.1

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

-0.00

0.0

1.1

—

(3027944) Amphetamines [Presence] in Urine

0.00

-0.00

0.0

1.2

—

(3027008) Opiates [Presence] in Urine

0.00

-0.00

0.0

1.1

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

-0.00

0.0

1.6

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.5

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

-0.00

0.0

1.9

—

32.71

—

(3025547) Thyroglobulin Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

2.4

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

1.49

—

(3044941) Cell count panel - Synovial fluid

0.00

-0.00

0.0

1.1

—

(42529406) Shigella sp [Presence] in Stool by Culture

0.00

-0.00

0.0

1.0

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

-0.00

0.0

1.3

—

(3028271) Lactate [Moles/volume] in Capillary blood

0.00

-0.00

0.0

1.6

—

1.48

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

-0.00

0.0

1.1

—

(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.6

—

Mortality – FinRegistry

↥

Association

Association between endpoint AB1_NOCARDIOSIS and mortality.

Females

No data

Males

Parameter	HR [95% CI]	p-value
AB1_NOCARDIOSIS	3.248 [1.86, 5.68]	< 0.001
Birth year	0.983 [0.97, 0.99]	< 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 52 out of 117 males with AB1_NOCARDIOSIS died.

Mortality risk

Mortality risk for people of age

years, who have AB1_NOCARDIOSIS.

N-year risk	Females	Males
1	No data	0.523%
5	No data	3.446%
10	No data	8.776%
15	No data	15.743%
20	No data	25.32%

Relationships between endpoints

↥

Index endpoint: AB1_NOCARDIOSIS – Nocardiosis

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

NAME	AB1_NOCARDIOSIS
CONTROL_EXCLUDE	AB1_OTHER_BACTERIAL
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	A43
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	A43
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Nocardiosis

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints