This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Amputation of ankle
AMPUTATION_ANKLE
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
53 |
4. Check minimum number of eventsNone |
53 |
5. Include endpointsNone |
53 |
6. Filter based on genotype QC (FinnGen only) |
46 |
Control definitions (FinnGen only)
- Control exclude
- AMPUTATION
Extra metadata
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Amputation of ankle
based on the number of shared cases.
Similar with more cases:
- Amputation
- Peripheral artery operations in Hilmo
- Peripheral artery disease
- Diseases of arteries, arterioles and capillaries
- Cardiovascular diseases
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 46 | 15 | 31 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 72.79 | 74.52 | 71.95 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
15
25
8.21
6.68
17.4
11.9
24.64
25.55
mmol/l
0.33
15
25
17
48
4.94
5.97
10.2
3.9
—
—
—
0
0
19
67
4.04
4.92
4.1
3.5
0.75
0.82
mmol/l
1.62
19
62
13
33
5.01
4.20
1.9
1.5
—
—
—
0
0
14
44
4.08
4.17
13.6
9.8
111.50
117.48
g/l
0.51
14
44
12
30
4.98
3.93
8.1
4.7
22.79
24.12
mmol/l
0.36
12
30
7
8
9.98
3.91
2.3
1.3
—
—
—
0
0
12
36
4.09
3.32
19.2
10.0
1.29
1.31
mmol/l
0.02
12
36
8
21
4.35
2.59
2.4
1.2
—
—
—
0
0
14
60
2.88
2.50
1.8
1.6
—
—
—
0
0
29
181
2.52
2.44
5.6
2.7
—
—
estimate
—
0
0
5
8
6.81
2.43
4.8
2.6
14.14
17.85
%
—
5
8
5
8
6.81
2.43
1.2
1.1
—
—
—
0
0
11
42
3.09
2.34
5.4
2.3
5.73
9.49
umol/l
0.55
11
37
16
82
2.43
1.99
2.1
1.6
—
—
—
0
0
13
61
2.55
1.93
1.8
1.5
—
—
—
0
0
35
255
2.38
1.88
11.1
5.1
8.10
6.73
mmol/l
0.73
35
241
16
86
2.29
1.77
5.3
2.4
—
—
—
0
0
5
13
4.16
1.76
1.2
1.3
—
—
—
0
0
5
14
3.85
1.66
4.2
2.6
26.66
24.52
mmol/l
—
5
14
5
15
3.59
1.56
1.6
1.0
—
—
—
0
0
29
212
1.93
1.35
20.3
7.9
1.18
1.19
mmol/l
0.67
22
185
22
158
1.72
1.00
4.9
3.5
—
—
—
0
0
11
171
0.54
0.97
2.6
5.4
18.16
21.89
%
—
5
97
12
76
1.77
0.81
2.9
2.9
4.60
0.86
e6/l
—
5
44
28
227
1.56
0.72
6.0
4.1
0.00
0.00
estimate
—
6
45
19
141
1.58
0.72
2.2
1.7
15.54
20.23
nmol/l
0.87
19
110
17
124
1.57
0.68
4.8
3.2
0.48
0.23
e6/l
0.42
12
94
28
229
1.53
0.68
6.0
4.1
0.00
0.00
estimate
—
7
40
6
34
1.87
0.61
9.0
2.9
5.23
5.06
kpa
—
6
34
27
223
1.48
0.60
6.1
4.0
0.00
0.00
estimate
—
6
43
6
36
1.76
0.59
7.0
6.1
1.20
1.22
mmol/l
—
6
29
35
308
1.50
0.53
10.3
8.8
96.00
79.19
u/l
1.44
35
292
0
15
0.00
0.42
0.0
2.9
—
—
—
0
0
0
16
0.00
0.42
0.0
1.4
—
—
—
0
0
0
16
0.00
0.42
0.0
1.7
—
—
—
0
0
20
167
1.34
0.37
6.3
4.3
0.00
0.00
estimate
—
7
35
6
45
1.38
0.35
2.5
2.5
3.95
5.04
ug/l
—
6
40
18
149
1.33
0.35
3.8
2.6
2.23
2.34
mmol/l
2.37
18
128
16
133
1.30
0.29
7.1
3.9
0.00
0.00
estimate
—
5
39
0
13
0.00
0.21
0.0
1.6
—
46.69
—
0
13
0
14
0.00
0.20
0.0
3.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
207.93
—
0
14
14
120
1.24
0.19
5.8
4.1
0.00
0.00
estimate
—
7
35
33
345
0.86
0.11
8.5
7.7
46.58
40.83
mmol/mol
1.52
33
318
36
374
0.85
0.11
18.2
13.3
25.22
25.75
u/l
0.07
36
361
19
177
1.12
0.08
3.1
2.7
—
—
—
0
0
37
359
1.13
0.06
63.6
19.0
46.52
26.34
mg/l
2.43
37
309
37
378
0.91
0.03
64.1
25.7
103.65
88.22
umol/l
0.55
37
371
37
378
0.91
0.03
80.8
29.2
91.27
91.55
fl
0.12
37
373
37
378
0.91
0.03
84.3
29.9
36.32
40.04
%
4.00
37
373
37
378
0.91
0.03
81.6
29.4
118.35
134.40
g/l
5.22
37
373
37
373
0.96
0.00
71.0
23.2
4.11
4.02
mmol/l
1.00
37
363
37
373
0.96
0.00
68.9
23.0
138.62
139.51
mmol/l
1.05
37
363
10
95
1.07
0.00
3.0
2.9
2.54
2.46
mmol/l
—
10
81
19
192
0.98
0.00
2.1
2.2
72.78
89.63
pmol/l
—
10
99
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
7.7
—
56.00
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
87.29
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
785.74
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.0
—
1.17
—
0
6
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: AMPUTATION_ANKLE – Amputation of ankle
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).