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Carcinoma in situ of oesophagus

CD2_INSITU_OESOPHAGUS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

  • not C3_OESOPHAGUS
556605

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D00.1&
  • Hospital discharge: ICD-9 2301A
  • Cause of death: ICD-10 D00.1&
  • Cause of death: ICD-9 2301A
  • Cancer registry: Topography ICD-O-3 C15
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 2

3 out of 7 registries used, show all original rules.

49

4. Check minimum number of events

None

49

5. Include endpoints

None

49

6. Filter based on genotype QC (FinnGen only)

45

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9
Parent code in ICD-10
D00
Name in latin
Carcinoma in situ coli

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 45 14 31
Unadjusted period prevalence (%) 0.01 0.00 0.01
Median age at first event (years) 69.63 70.95 69.03

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
32
59
14.86
19.98
4.0
1.2
—
—
—
0
0
40
231
5.89
5.95
19.9
15.2
1.26
1.27
inr
0.05
34
190
16
52
4.15
4.61
3.1
2.7
77.00
68.14
e9/l
0.37
11
38
14
42
4.32
4.46
3.1
3.0
0.19
0.21
g/l
0.49
14
37
34
191
3.82
4.25
6.4
3.2
—
—
estimate
—
0
0
30
158
3.48
4.10
3.6
2.2
—
—
—
0
0
29
151
3.40
4.01
4.0
2.6
—
—
—
0
0
40
269
4.26
3.86
6.6
5.7
6.97
6.81
mmol/l
0.19
40
260
14
47
3.82
3.79
3.9
5.1
7.37
7.36
ph
—
8
34
13
42
3.90
3.70
1.6
1.4
—
—
—
0
0
28
148
3.21
3.69
2.0
1.8
18.66
22.93
nmol/l
0.95
23
122
10
27
4.41
3.10
1.6
1.2
—
—
—
0
0
8
192
0.30
2.84
3.4
4.3
299.74
68.84
e6/l
—
8
144
8
182
0.33
2.59
3.4
3.4
20.86
33.80
e6/l
—
8
142
25
147
2.50
2.40
3.8
3.5
20.51
62.04
mg/l
1.39
14
102
30
194
2.51
2.32
5.5
4.6
62.37
49.36
ng/l
0.17
25
158
17
86
2.53
2.20
3.0
2.7
22.98
24.03
%
0.09
12
81
25
152
2.38
2.17
3.8
3.4
7.25
8.27
mmol/l
0.42
19
132
11
45
2.89
2.11
1.5
1.5
—
—
—
0
0
7
156
0.35
2.07
2.3
3.2
0.00
0.35
e6/l
—
7
117
33
232
2.42
2.00
10.0
9.0
1.21
1.21
mmol/l
0.03
28
208
25
157
2.27
1.97
4.7
4.3
2.49
10.12
mg/mmol
1.72
15
110
31
215
2.30
1.90
10.9
5.4
35.06
34.70
g/l
0.14
31
204
8
29
3.11
1.89
7.1
3.0
—
—
—
0
0
7
23
3.39
1.88
1.7
2.1
—
0.00
estimate
—
0
6
25
163
2.14
1.73
2.6
2.0
1.09
1.34
mmol/l
0.74
19
131
5
14
3.86
1.66
1.0
1.3
—
—
—
0
0
30
213
2.13
1.64
3.3
2.4
87.78
89.92
pmol/l
0.10
21
122
9
43
2.35
1.40
7.7
2.9
7.38
7.43
ph
—
9
36
14
79
2.10
1.35
1.5
1.7
2.54
2.75
g/l
—
6
50
11
57
2.21
1.30
1.6
1.2
—
—
—
0
0
5
21
2.54
1.12
3.4
2.0
423.80
557.05
ug/l
—
5
21
9
51
1.94
1.02
1.8
1.7
—
—
—
0
0
21
150
1.72
0.97
8.3
6.6
—
—
—
0
0
8
48
1.80
0.84
2.9
2.0
—
—
—
0
0
7
38
1.99
0.78
3.0
3.6
—
—
—
0
0
7
40
1.88
0.75
4.6
10.7
1.00
1.63
mmol/l
—
7
40
7
41
1.83
0.74
1.3
3.4
8.14
7.63
umol/l
—
7
35
20
151
1.56
0.70
3.4
5.0
—
—
—
0
0
0
22
0.00
0.61
0.0
11.3
—
—
—
0
0
10
142
0.62
0.58
3.3
3.8
—
—
—
0
0
12
84
1.58
0.56
1.9
2.1
0.56
1.46
mg/l
—
7
72
8
117
0.62
0.55
3.3
3.3
428.38
546.45
mosm/kgh2o
—
8
103
22
179
1.43
0.51
6.6
4.5
—
—
—
0
0
7
48
1.54
0.49
1.7
1.8
—
—
—
0
0
7
102
0.63
0.46
1.4
2.9
2.39
2.47
mmol/l
—
7
88
5
34
1.53
0.42
1.6
1.7
—
—
—
0
0
23
194
1.36
0.41
9.3
6.6
61.09
60.20
%
0.14
23
183
5
35
1.48
0.40
2.8
4.6
—
—
—
0
0
13
100
1.41
0.39
1.3
1.4
—
—
—
0
0
10
73
1.47
0.38
2.2
2.1
—
—
—
0
0
17
141
1.32
0.32
3.4
4.3
0.00
0.04
estimate
—
7
50
40
379
1.37
0.25
9.4
7.4
42.94
40.28
mmol/mol
0.81
32
358
7
91
0.73
0.25
3.1
3.8
396.43
175.00
ng/l
—
7
79
5
39
1.31
0.24
2.0
1.4
—
—
—
0
0
38
361
1.27
0.23
6.2
5.0
2.01
2.09
mu/l
0.11
30
324
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
6
47
1.32
0.21
5.0
11.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
6.43
—
0
7
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
805.00
—
0
8
6
50
1.23
0.21
1.2
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
7
61
1.17
0.18
1.6
1.8
—
—
—
0
0
22
239
0.85
0.15
3.5
4.6
0.00
0.00
estimate
—
7
52
22
238
0.86
0.14
3.7
4.5
0.00
28.00
estimate
—
7
58
22
235
0.88
0.10
3.7
4.5
0.00
0.00
estimate
—
6
54
6
57
1.06
0.09
1.3
2.8
67.43
66.19
g/l
—
6
52
8
92
0.84
0.07
6.0
5.5
—
—
—
0
0
19
184
1.05
0.00
3.3
4.3
6.04
6.33
ph
0.47
14
96
28
283
0.97
0.00
5.8
5.1
—
47.57
—
0
7
15
155
0.95
0.00
3.5
3.3
—
—
—
0
0
17
175
0.96
0.00
3.9
4.8
0.00
0.06
estimate
—
5
47
12
122
0.98
0.00
4.4
7.2
—
—
—
0
0
0
7
0.00
0.00
0.0
5.4
—
320.29
—
0
7
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
3.1
—
0.48
—
0
9
8
81
0.99
0.00
7.3
6.9
102.00
103.67
mmol/l
—
8
81
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.3
—
88.90
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
41
404
1.12
-0.00
7.4
6.4
2.25
2.55
mmol/l
1.22
36
371
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.8
—
0.94
—
0
8
40
396
1.07
-0.00
7.4
5.3
1.43
1.41
mmol/l
0.11
35
362
0
8
0.00
-0.00
0.0
4.0
—
100.75
—
0
8
0
6
0.00
-0.00
0.0
3.0
—
38.58
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
13
130
1.00
-0.00
2.9
4.3
0.00
0.00
estimate
—
5
43
0
5
0.00
-0.00
0.0
2.8
—
5.94
—
0
5
0
6
0.00
-0.00
0.0
1.7
—
200.33
—
0
6
40
396
1.07
-0.00
7.3
5.5
4.18
4.42
mmol/l
0.71
35
364
40
399
1.02
-0.00
7.6
5.6
6.06
6.08
mmol/l
0.05
33
365
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_OESOPHAGUS – Carcinoma in situ of oesophagus

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).