This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Deficiency of other/unspecified vitamins
E4_VIT_NAS_DEF
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
51 |
4. Check minimum number of eventsNone |
51 |
5. Include endpointsNone |
51 |
6. Filter based on genotype QC (FinnGen only) |
48 |
Control definitions (FinnGen only)
- Control exclude
- E4_NUTRIDEF
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Deficiency of other/unspecified vitamins
based on the number of shared cases.
Similar with more cases:
- Vitamin deficiency
- Vitamin deficiency, wide
- Other nutritional deficiencies
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: unknown.
No upset table: unknown.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 344 | 188 | 154 |
| Only index persons | 302 | 165 | 137 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.01 | 0.00 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 60.93 | 59.56 | 62.55 |
| Only index persons | 61.44 | 59.66 | 63.58 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 48 | 26 | 22 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 62.28 | 59.26 | 65.84 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 51
- Matched controls
- 510
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A98, ,
ICD-O-3
+∞
59.6
45
*
N02BE01, ,
ATC
paracetamol; systemic, rectal
+∞
50.8
40
*
M01AE01, ,
ATC
ibuprofen; systemic, rectal
+∞
47.5
38
*
A02BC02, ,
ATC
pantoprazole; systemic
+∞
47.5
38
*
J01DB01, ,
ATC
cefalexin; oral
+∞
45.9
37
*
J01CA04, ,
ATC
amoxicillin; systemic
+∞
42.9
35
*
E568, ,
ICD-10 Finland
Deficiency of other vitamins
+∞
39.9
33
*
J01CE02, ,
ATC
phenoxymethylpenicillin; oral
+∞
38.5
32
*
J01AA02, ,
ATC
doxycycline; systemic
+∞
38.5
32
*
R03AC02, ,
ATC
salbutamol; inhalant
+∞
32.9
28
*
J01DA01, ,
ATC
[U] cefalexin
+∞
32.9
28
*
M01AE02, ,
ATC
naproxen; oral, rectal
+∞
32.9
28
*
I10, ,
ICD-10 Finland
Essential (primary) hypertension
+∞
31.5
27
*
C07AB07, ,
ATC
bisoprolol; oral
+∞
31.5
27
*
WX110, ,
ICD-O-3
+∞
31.5
27
*
M01AB05, ,
ATC
diclofenac; systemic, rectal
+∞
30.2
26
*
N02AX02, ,
ATC
tramadol; systemic, rectal
+∞
28.9
25
*
SAA01, ,
ICD-O-3
+∞
28.9
25
*
J01FA10, ,
ATC
azithromycin; systemic
+∞
27.6
24
*
M03BX02, ,
ATC
tizanidine; oral
+∞
26.3
23
*
R06AE07, ,
ATC
cetirizine; oral
+∞
26.3
23
*
UJD10, ,
ICD-O-3
+∞
26.3
23
*
J01CR02, ,
ATC
amoxicillin and beta-lactamase inhibitor; systemic
+∞
25.1
22
*
H02AB06, ,
ATC
prednisolone; systemic
+∞
25.1
22
*
K021, ,
ICD-O-3
+∞
25.1
22
*
GD1AA, ,
ICD-O-3
+∞
25.1
22
*
EB1AA, ,
ICD-O-3
+∞
23.8
21
*
S18, ,
ICD-O-3
+∞
23.8
21
*
SAA02, ,
ICD-O-3
+∞
22.6
20
*
SFA10, ,
ICD-O-3
+∞
22.6
20
*
SPAT1256, ,
ICD-O-3
+∞
22.6
20
*
W01, ,
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
+∞
22.6
20
*
WZC00, ,
ICD-O-3
+∞
21.3
19
*
WX290, ,
ICD-O-3
+∞
21.3
19
*
A02BC05, ,
ATC
esomeprazole; systemic
+∞
21.3
19
*
SFA20, ,
ICD-O-3
+∞
21.3
19
*
N02AA59, ,
ATC
codeine, combinations excl. psycholeptics; systemic
+∞
21.3
19
*
M01AH05, ,
ATC
etoricoxib; oral
+∞
21.3
19
*
P01AB01, ,
ATC
metronidazole; oral, rectal
+∞
20.1
18
*
SPAT1263, ,
ICD-O-3
+∞
20.1
18
*
ZXE00, ,
ICD-O-3
+∞
20.1
18
*
SPAT1249, ,
ICD-O-3
+∞
20.1
18
*
103, ,
Kela drug reimbursment
Diabetes, insulin-treated
+∞
20.1
18
*
SPAT1253, ,
ICD-O-3
+∞
20.1
18
*
N06AX11, ,
ATC
mirtazapine; oral
+∞
20.1
18
*
C03CA01, ,
ATC
furosemide; systemic
+∞
20.1
18
*
S01XA20, ,
ATC
artificial tears and other indifferent preparations; ophthalmic
+∞
20.1
18
*
M02AA07, ,
ATC
piroxicam; topical
+∞
18.9
17
*
A10BA02, ,
ATC
metformin; oral
+∞
18.9
17
*
SPAT1310, ,
ICD-O-3
+∞
18.9
17
*
N06AB04, ,
ATC
citalopram; systemic
+∞
18.9
17
*
AA1AD, ,
ICD-O-3
+∞
18.9
17
*
215, ,
Kela drug reimbursment
Diabetes, non-insulin-treated
+∞
18.9
17
*
C10AA01, ,
ATC
simvastatin; oral
+∞
18.9
17
*
N02AJ06, ,
ATC
codeine and paracetamol; systemic
+∞
17.7
16
*
SPAT1223, ,
ICD-O-3
+∞
17.7
16
*
J01MA02, ,
ATC
ciprofloxacin; systemic
+∞
17.7
16
*
ZXE10, ,
ICD-O-3
+∞
17.7
16
*
WYA05, ,
ICD-O-3
+∞
17.7
16
*
I10, ,
ICD-O-3
+∞
17.7
16
*
R05FA02, ,
ATC
opium derivatives and expectorants; systemic
+∞
16.5
15
*
203, ,
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
+∞
16.5
15
*
SAA03, ,
ICD-O-3
+∞
16.5
15
*
Z012, ,
ICD-O-3
+∞
16.5
15
*
L28, ,
ICD-O-3
+∞
16.5
15
*
EB1SA, ,
ICD-O-3
+∞
16.5
15
*
EBA00, ,
ICD-O-3
+∞
16.5
15
*
SPAT1216, ,
ICD-O-3
+∞
16.5
15
*
GD1QA, ,
ICD-O-3
+∞
16.5
15
*
J189, ,
ICD-10 Finland
Pneumonia, unspecified
+∞
16.5
15
*
N05AH04, ,
ATC
quetiapine; oral
+∞
16.5
15
*
C09CA06, ,
ATC
candesartan; oral
+∞
16.5
15
*
ZXD05, ,
ICD-O-3
+∞
15.4
14
*
R4110, ,
ICD-O-3
+∞
15.4
14
*
Z2221, ,
ICD-O-3
+∞
15.4
14
*
N05BA04, ,
ATC
oxazepam; oral
+∞
15.4
14
*
R05FB02, ,
ATC
cough suppressants and expectorants; systemic
+∞
15.4
14
*
SPAT1250, ,
ICD-O-3
+∞
15.4
14
*
CJE20, ,
ICD-O-3
+∞
15.4
14
*
A03FA01, ,
ATC
metoclopramide; systemic, rectal
+∞
15.4
14
*
R01AD12, ,
ATC
fluticasone furoate; nasal
+∞
15.4
14
*
R01AD08, ,
ATC
fluticasone; nasal
+∞
15.4
14
*
C07AA05, ,
ATC
propranolol; systemic
+∞
15.4
14
*
S01CA01, ,
ATC
dexamethasone and antiinfectives; ophthalmic
+∞
15.4
14
*
J01FA06, ,
ATC
roxithromycin; oral
+∞
15.4
14
*
R104, ,
ICD-10 Finland
Other and unspecified abdominal pain
+∞
15.4
14
*
J069, ,
ICD-O-3
+∞
15.4
14
*
A12AX, ,
ATC
Calcium, combinations with vitamin D and/or other drugs
+∞
15.4
14
*
EB1HA, ,
ICD-O-3
+∞
15.4
14
*
SPAT1153, ,
ICD-O-3
+∞
15.4
14
*
R74, ,
ICD-O-3
+∞
15.4
14
*
SPAT1312, ,
ICD-O-3
+∞
14.2
13
*
Z871, ,
ICD-O-3
+∞
14.2
13
*
LC2BE, ,
ICD-O-3
+∞
14.2
13
*
C10AA05, ,
ATC
atorvastatin; oral
+∞
14.2
13
*
J01CA08, ,
ATC
pivmecillinam; oral
+∞
14.2
13
*
M03BC51, ,
ATC
orphenadrine, combinations; systemic
+∞
14.2
13
*
M796, ,
ICD-O-3
+∞
14.2
13
*
A09, ,
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
+∞
14.2
13
*
C08CA01, ,
ATC
amlodipine; oral
+∞
14.2
13
*
T90, ,
ICD-O-3
+∞
14.2
13
*
A02BC01, ,
ATC
omeprazole; systemic
+∞
14.2
13
*
205, ,
Kela drug reimbursment
Chronic hypertension
+∞
14.2
13
*
R01BA52, ,
ATC
pseudoephedrine, combinations; oral
+∞
14.2
13
*
ZXD10, ,
ICD-O-3
+∞
14.2
13
*
B03BA03, ,
ATC
hydroxocobalamin; parenteral
+∞
14.2
13
*
Z3231, ,
ICD-O-3
+∞
13.1
12
*
R05DA20, ,
ATC
opium alkaloids and derivatives - combinations
+∞
13.1
12
*
G03CA03, ,
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
+∞
13.1
12
*
L03, ,
ICD-O-3
+∞
13.1
12
*
J01MA12, ,
ATC
levofloxacin; systemic
+∞
13.1
12
*
M796, ,
ICD-10 Finland
Pain in limb
+∞
13.1
12
*
J02AC01, ,
ATC
fluconazole; systemic
+∞
13.1
12
*
D07AC01, ,
ATC
betamethasone; topical
+∞
13.1
12
*
R03BA05, ,
ATC
fluticasone; inhalant
+∞
13.1
12
*
A28, ,
ICD-O-3
+∞
13.1
12
*
E119, ,
ICD-10 Finland
Type 2 diabetes mellitus, without complications
+∞
13.1
12
*
N03AX16, ,
ATC
[U] pregabalin
+∞
13.1
12
*
E0000UV, ,
ATC
+∞
13.1
12
*
ZXA00, ,
ICD-O-3
+∞
13.1
12
*
R05, ,
ICD-O-3
+∞
13.1
12
*
KMAK, ,
ICD-O-3
+∞
13.1
12
*
R074, ,
ICD-10 Finland
Chest pain, unspecified
+∞
13.1
12
*
N06AB10, ,
ATC
escitalopram; oral
+∞
13.1
12
*
A02BC03, ,
ATC
lansoprazole; oral
+∞
13.1
12
*
-1, ,
ICD-O-3
+∞
13.1
12
*
A06AD11, ,
ATC
lactulose; oral
+∞
11.9
11
*
N06AX16, ,
ATC
venlafaxine; oral
+∞
11.9
11
*
SPAT1254, ,
ICD-O-3
+∞
11.9
11
*
R06AX27, ,
ATC
desloratadine; oral
+∞
11.9
11
*
K045, ,
ICD-O-3
+∞
11.9
11
*
N06AX21, ,
ATC
duloxetine; oral
+∞
11.9
11
*
Z3226, ,
ICD-O-3
+∞
11.9
11
*
B01AB05, ,
ATC
enoxaparin; parenteral
+∞
11.9
11
*
N05CF01, ,
ATC
zopiclone; oral
+∞
11.9
11
*
SPAT1148, ,
ICD-O-3
+∞
11.9
11
*
J01EA01, ,
ATC
trimethoprim; systemic
+∞
11.9
11
*
E569, ,
ICD-10 Finland
Vitamin deficiency, unspecified
+∞
11.9
11
*
WX408, ,
ICD-O-3
+∞
11.9
11
*
J01FF01, ,
ATC
clindamycin; systemic
+∞
11.9
11
*
SDA02, ,
ICD-O-3
+∞
11.9
11
*
Z010, ,
ICD-10 Finland
Examination of eyes and vision
+∞
11.9
11
*
ZXA05, ,
ICD-O-3
+∞
11.9
11
*
R5110, ,
ICD-O-3
+∞
11.9
11
*
C01DA08, ,
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
+∞
11.9
11
*
SPAT1230, ,
ICD-O-3
+∞
11.9
11
*
J01EE02, ,
ATC
sulfadiazine and trimethoprim; systemic
+∞
10.8
10
*
XF400, ,
ICD-O-3
+∞
10.8
10
*
SPAT1262, ,
ICD-O-3
+∞
10.8
10
*
XCK10, ,
ICD-O-3
+∞
10.8
10
*
SPAT1222, ,
ICD-O-3
+∞
10.8
10
*
SPAT1301, ,
ICD-O-3
+∞
10.8
10
*
R42, ,
ICD-10 Finland
Dizziness and giddiness
+∞
10.8
10
*
C01DA02, ,
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
+∞
10.8
10
*
B02AA02, ,
ATC
tranexamic acid; systemic
+∞
10.8
10
*
H03AA01, ,
ATC
levothyroxine sodium; systemic
+∞
10.8
10
*
B81, ,
ICD-O-3
+∞
10.8
10
*
A10AE04, ,
ATC
insulin glargine; parenteral
+∞
10.8
10
*
SPAT1149, ,
ICD-O-3
+∞
10.8
10
*
R01AD09, ,
ATC
mometasone; nasal
+∞
10.8
10
*
65000, ,
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
+∞
10.8
10
*
JN3AE, ,
ICD-O-3
+∞
10.8
10
*
F329, ,
ICD-10 Finland
Depressive episode, unspecified
+∞
10.8
10
*
M01AE03, ,
ATC
ketoprofen; systemic, rectal
+∞
10.8
10
*
SFC01, ,
ICD-O-3
+∞
10.8
10
*
M545, ,
ICD-O-3
+∞
10.8
10
*
N05BA01, ,
ATC
diazepam; systemic, rectal
+∞
10.8
10
*
N05AX08, ,
ATC
risperidone; systemic
+∞
10.8
10
*
L17, ,
ICD-O-3
+∞
10.8
10
*
N06AA09, ,
ATC
amitriptyline; systemic
+∞
10.8
10
*
J459, ,
ICD-10 Finland
Asthma, unspecified
+∞
10.8
10
*
WZB00, ,
ICD-O-3
+∞
9.7
9
*
Z018, ,
ICD-10 Finland
Other specified special examinations
+∞
9.7
9
*
N05CD07, ,
ATC
temazepam; oral
+∞
9.7
9
*
I509, ,
ICD-10 Finland
Heart failure, unspecified
+∞
9.7
9
*
C09CA01, ,
ATC
losartan; oral
+∞
9.7
9
*
SCA01, ,
ICD-O-3
+∞
9.7
9
*
N03AX12, ,
ATC
[U] gabapentin; oral
+∞
9.7
9
*
I48, ,
ICD-10 Finland
Atrial fibrillation and flutter
+∞
9.7
9
*
SPAT1053, ,
ICD-O-3
+∞
9.7
9
*
Z712, ,
ICD-O-3
+∞
9.7
9
*
Z760, ,
ICD-O-3
+∞
9.7
9
*
CK2S4, ,
ICD-O-3
+∞
9.7
9
*
H251, ,
ICD-10 Finland
Senile nuclear cataract
+∞
9.7
9
*
FM1AE, ,
ICD-O-3
+∞
9.7
9
*
SPAT1240, ,
ICD-O-3
+∞
9.7
9
*
R060, ,
ICD-10 Finland
Dyspnoea
+∞
9.7
9
*
X58, ,
ICD-10 Finland
Exposure to other specified factors
+∞
9.7
9
*
A499, ,
ICD-10 Finland
Bacterial infection, unspecified
+∞
9.7
9
*
R568, ,
ICD-10 Finland
Other and unspecified convulsions
+∞
9.7
9
*
B01AA03, ,
ATC
warfarin; systemic
+∞
9.7
9
*
FM1EE, ,
ICD-O-3
+∞
9.7
9
*
D07AC13, ,
ATC
mometasone; topical
+∞
9.7
9
*
R21, ,
ICD-O-3
+∞
9.7
9
*
R03DC03, ,
ATC
montelukast; oral
+∞
9.7
9
*
TPH04, ,
ICD-O-3
+∞
9.7
9
*
D07CC01, ,
ATC
betamethasone and antibiotics; topical
+∞
9.7
9
*
S29, ,
ICD-O-3
+∞
9.7
9
*
I639, ,
ICD-10 Finland
Cerebral infarction, unspecified
+∞
9.7
9
*
I48, ,
ICD-O-3
+∞
8.6
8
*
207, ,
Kela drug reimbursment
Chronic arrhythmias
+∞
8.6
8
*
SDA03, ,
ICD-O-3
+∞
8.6
8
*
D19, ,
ICD-O-3
+∞
8.6
8
*
R03AK07, ,
ATC
formoterol and budesonide; inhalant
+∞
8.6
8
*
M545, ,
ICD-10 Finland
Low back pain
+∞
8.6
8
*
ZXA10, ,
ICD-O-3
+∞
8.6
8
*
R83, ,
ICD-O-3
+∞
8.6
8
*
SPAT1229, ,
ICD-O-3
+∞
8.6
8
*
M255, ,
ICD-O-3
+∞
8.6
8
*
WX002, ,
ICD-O-3
+∞
8.6
8
*
J010, ,
ICD-O-3
+∞
8.6
8
*
Z000, ,
ICD-10 Finland
General medical examination
+∞
8.6
8
*
UJF32, ,
ICD-O-3
+∞
8.6
8
*
J069, ,
ICD-10 Finland
Acute upper respiratory infection, unspecified
+∞
8.6
8
*
N06AB03, ,
ATC
fluoxetine; oral
+∞
8.6
8
*
JN3AD, ,
ICD-O-3
+∞
8.6
8
*
N06AB06, ,
ATC
sertraline; oral
+∞
8.6
8
*
R53, ,
ICD-O-3
+∞
8.6
8
*
R01AD58, ,
ATC
fluticasone, combinations; nasal
+∞
8.6
8
*
D82, ,
ICD-O-3
+∞
8.6
8
*
S060, ,
ICD-10 Finland
Concussion
+∞
8.6
8
*
E000001, ,
ATC
+∞
8.6
8
*
WX700, ,
ICD-O-3
+∞
8.6
8
*
M544, ,
ICD-O-3
+∞
8.6
8
*
J01FA09, ,
ATC
clarithromycin; systemic
+∞
8.6
8
*
SFA30, ,
ICD-O-3
+∞
8.6
8
*
UJF30, ,
ICD-O-3
+∞
8.6
8
*
S01GX01, ,
ATC
cromoglicic acid; ophthalmic
+∞
8.6
8
*
SPAT1156, ,
ICD-O-3
+∞
8.6
8
*
A06AC01, ,
ATC
ispaghula (psylla seeds); oral
+∞
8.6
8
*
SPAT1306, ,
ICD-O-3
+∞
7.5
7
*
ZXE02, ,
ICD-O-3
+∞
7.5
7
*
E11, ,
ICD-O-3
+∞
7.5
7
*
M01AX05, ,
ATC
glucosamine; oral
+∞
7.5
7
*
D07AB08, ,
ATC
desonide; topical
+∞
7.5
7
*
Z3229, ,
ICD-O-3
+∞
7.5
7
*
SPAT1260, ,
ICD-O-3
+∞
7.5
7
*
E119, ,
ICD-O-3
+∞
7.5
7
*
F322, ,
ICD-10 Finland
Severe depressive episode without psychotic symptoms
+∞
7.5
7
*
Z961, ,
ICD-10 Finland
Presence of intraocular lens
+∞
7.5
7
*
R103, ,
ICD-10 Finland
Pain localized to other parts of lower abdomen
+∞
7.5
7
*
SPAT1281, ,
ICD-O-3
+∞
7.5
7
*
C09AA05, ,
ATC
ramipril; oral
+∞
7.5
7
*
M01AC06, ,
ATC
meloxicam; systemic, rectal
+∞
7.5
7
*
WZC30, ,
ICD-O-3
+∞
7.5
7
*
D01AC20, ,
ATC
imidazoles/triazoles in combination with corticosteroids; topical
+∞
7.5
7
*
R101, ,
ICD-10 Finland
Pain localized to upper abdomen
+∞
7.5
7
*
J01DA09, ,
ATC
[U] cefadroxil
+∞
7.5
7
*
R03AK06, ,
ATC
salmeterol and fluticasone; inhalant
+∞
7.5
7
*
D07AB02, ,
ATC
hydrocortisone butyrate; topical
+∞
7.5
7
*
L12, ,
ICD-O-3
+∞
7.5
7
*
N02AE01, ,
ATC
buprenorphine; parenteral, sublingual, transdermal
+∞
7.5
7
*
Z718, ,
ICD-10 Finland
Other specified counselling
+∞
7.5
7
*
K573, ,
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
+∞
7.5
7
*
WX404, ,
ICD-O-3
+∞
7.5
7
*
A10AC01, ,
ATC
insulin (human); parenteral
+∞
7.5
7
*
Z016, ,
ICD-O-3
+∞
7.5
7
*
J451, ,
ICD-10 Finland
Nonallergic asthma
+∞
7.5
7
*
A46, ,
ICD-10 Finland
Erysipelas
+∞
7.5
7
*
N05BA12, ,
ATC
alprazolam; oral
+∞
7.5
7
*
WZA90, ,
ICD-O-3
+∞
7.5
7
*
G473, ,
ICD-10 Finland
Sleep apnoea
+∞
7.5
7
*
Z004, ,
ICD-10 Finland
General psychiatric examination, not elsewhere classified
+∞
7.5
7
*
SPAT1033, ,
ICD-O-3
+∞
7.5
7
*
J459, ,
ICD-O-3
+∞
7.5
7
*
M03BC01, ,
ATC
orphenadrine (citrate); systemic
+∞
7.5
7
*
290, ,
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
+∞
7.5
7
*
K802, ,
ICD-10 Finland
Calculus of gallbladder without cholecystitis
+∞
7.5
7
*
GD1PA, ,
ICD-O-3
+∞
7.5
7
*
E7801, ,
ICD-10 Finland
Pure hypercholesterolaemia
+∞
7.5
7
*
J05AB01, ,
ATC
aciclovir; systemic
+∞
7.5
7
*
K0364, ,
ICD-O-3
+∞
7.5
7
*
R11, ,
ICD-10 Finland
Nausea and vomiting
+∞
7.5
7
*
SDA04, ,
ICD-O-3
+∞
7.5
7
*
SFA40, ,
ICD-O-3
+∞
7.5
7
*
R02, ,
ICD-O-3
+∞
7.5
7
*
R509, ,
ICD-10 Finland
Fever, unspecified
+∞
7.5
7
*
JKA21, ,
ICD-O-3
+∞
7.5
7
*
R53, ,
ICD-10 Finland
Malaise and fatigue
+∞
7.5
7
*
A02BA02, ,
ATC
ranitidine; systemic
+∞
6.4
6
*
SPAT1325, ,
ICD-O-3
+∞
6.4
6
*
KC1EE, ,
ICD-O-3
+∞
6.4
6
*
J01AA04, ,
ATC
lymecycline; systemic
+∞
6.4
6
*
Z718, ,
ICD-O-3
+∞
6.4
6
*
R238, ,
ICD-O-3
+∞
6.4
6
*
L13, ,
ICD-O-3
+∞
6.4
6
*
C10AA07, ,
ATC
rosuvastatin; oral
+∞
6.4
6
*
R03BA01, ,
ATC
beclometasone; inhalant
+∞
6.4
6
*
H811, ,
ICD-O-3
+∞
6.4
6
*
F101, ,
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
+∞
6.4
6
*
M171, ,
ICD-10 Finland
Other primary gonarthrosis
+∞
6.4
6
*
SPAT1245, ,
ICD-O-3
+∞
6.4
6
*
F29, ,
ICD-O-3
+∞
6.4
6
*
SPAT1211, ,
ICD-O-3
+∞
6.4
6
*
D01BA02, ,
ATC
terbinafine; oral
+∞
6.4
6
*
JN4BD, ,
ICD-O-3
+∞
6.4
6
*
GD1UA, ,
ICD-O-3
+∞
6.4
6
*
I251, ,
ICD-10 Finland
Atherosclerotic heart disease
+∞
6.4
6
*
SPAT1283, ,
ICD-O-3
+∞
6.4
6
*
P01, ,
ICD-O-3
+∞
6.4
6
*
H02AB07, ,
ATC
prednisone; oral
+∞
6.4
6
*
Z027, ,
ICD-O-3
+∞
6.4
6
*
J01FA01, ,
ATC
erythromycin; systemic
+∞
6.4
6
*
N05CF02, ,
ATC
zolpidem; oral
+∞
6.4
6
*
N02AA05, ,
ATC
oxycodone; systemic
+∞
6.4
6
*
L01, ,
ICD-O-3
+∞
6.4
6
*
XPX99, ,
ICD-O-3
+∞
6.4
6
*
J010, ,
ICD-10 Finland
Acute maxillary sinusitis
+∞
6.4
6
*
NF1AA, ,
ICD-O-3
+∞
6.4
6
*
N06CA01, ,
ATC
amitriptyline and psycholeptics; systemic
+∞
6.4
6
*
R03AC12, ,
ATC
salmeterol; inhalant
+∞
6.4
6
*
H81, ,
ICD-O-3
+∞
6.4
6
*
M01AH01, ,
ATC
celecoxib; oral
+∞
6.4
6
*
112, ,
Kela drug reimbursment
Severe psychotic and other severe mental disorders
+∞
6.4
6
*
R104, ,
ICD-O-3
+∞
6.4
6
*
N06AX12, ,
ATC
bupropion; oral
+∞
6.4
6
*
NH3AA, ,
ICD-O-3
+∞
6.4
6
*
B01AF02, ,
ATC
apixaban; oral
+∞
6.4
6
*
J02AC02, ,
ATC
itraconazole; systemic
+∞
6.4
6
*
SPAT1137, ,
ICD-O-3
+∞
6.4
6
*
M04AA01, ,
ATC
allopurinol; systemic
+∞
6.4
6
*
UDC00, ,
ICD-O-3
+∞
6.4
6
*
R06AX13, ,
ATC
loratadine; oral
+∞
6.4
6
*
H13, ,
ICD-O-3
+∞
6.4
6
*
C07AB02, ,
ATC
metoprolol; systemic
+∞
6.4
6
*
R5180, ,
ICD-10 Finland
Headache
+∞
6.4
6
*
SGA01, ,
ICD-O-3
+∞
6.4
6
*
ZXE03, ,
ICD-O-3
+∞
6.4
6
*
R298, ,
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
+∞
6.4
6
*
WW200, ,
ICD-O-3
+∞
6.4
6
*
K219, ,
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
+∞
6.4
6
*
ZXE05, ,
ICD-O-3
+∞
6.4
6
*
SBB00, ,
ICD-O-3
+∞
6.4
6
*
EBA05, ,
ICD-O-3
+∞
6.4
6
*
R01AD05, ,
ATC
budesonide; nasal
+∞
6.4
6
*
G04CA02, ,
ATC
tamsulosin; oral
+∞
6.4
6
*
E117, ,
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
+∞
6.4
6
*
L08, ,
ICD-O-3
+∞
6.4
6
*
A04, ,
ICD-O-3
+∞
6.4
6
*
E6601, ,
ICD-10 Finland
Obesity due to excess calories
+∞
6.4
6
*
D07AD01, ,
ATC
clobetasol; topical
+∞
6.4
6
*
Z363, ,
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
+∞
6.4
6
*
WX892, ,
ICD-O-3
+∞
6.4
6
*
X59, ,
ICD-10 Finland
Exposure to unspecified factor
+∞
6.4
6
*
SGA02, ,
ICD-O-3
+∞
6.4
6
*
I509, ,
ICD-O-3
+∞
6.4
6
*
F419, ,
ICD-10 Finland
Anxiety disorder, unspecified
+∞
6.4
6
*
H02AB04, ,
ATC
methylprednisolone; systemic
+∞
6.4
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
20
60
4.84
6.55
3.0
1.6
1553.36
1115.16
nmol/l
0.86
14
49
28
124
3.79
5.21
2.3
1.9
74.25
91.02
pmol/l
1.18
15
55
32
170
3.37
4.23
11.4
6.1
1.18
1.22
mmol/l
1.58
24
145
11
26
5.09
3.78
4.2
1.6
—
—
—
0
0
7
13
6.05
2.98
2.1
1.3
—
—
—
0
0
25
142
2.49
2.56
8.9
4.0
42.06
55.38
ng/l
0.17
18
91
10
38
3.02
2.15
11.3
5.2
103.00
105.58
mmol/l
—
10
38
13
59
2.62
2.05
3.5
1.7
—
—
—
0
0
6
16
4.10
2.00
2.7
1.9
—
—
—
0
0
6
17
3.85
1.90
2.8
2.5
—
—
—
0
0
7
23
3.36
1.87
3.3
1.8
195.00
124.89
ng/l
—
7
18
5
12
4.49
1.87
9.4
3.0
25.22
24.57
mmol/l
—
5
12
38
285
2.31
1.81
5.3
4.4
15.33
11.40
mm/h
1.04
33
257
5
13
4.14
1.76
2.6
3.5
25.36
23.48
mmol/l
—
5
13
5
16
3.34
1.47
2.8
1.5
—
—
—
0
0
5
16
3.34
1.47
9.4
2.5
1.94
2.31
%
—
5
16
7
29
2.63
1.45
12.6
3.3
—
—
—
0
0
32
241
1.88
1.30
6.2
3.2
53.96
41.48
u/l
0.43
27
227
24
170
1.78
1.15
15.8
9.8
1.21
1.24
inr
—
10
53
40
337
1.87
0.99
34.4
12.5
76.22
83.29
ml/min/173m2
0.99
34
267
8
45
1.92
0.89
2.9
1.8
33.88
28.24
s
—
8
45
14
91
1.74
0.86
4.0
2.7
318.86
342.29
umol/l
0.36
14
77
18
129
1.61
0.78
3.7
3.3
—
—
—
0
0
43
380
1.84
0.77
39.4
12.6
20.83
20.18
mg/l
0.06
36
290
14
95
1.65
0.74
1.4
1.3
1.13
1.23
u/ml
—
6
21
12
79
1.68
0.70
2.9
2.0
—
—
—
0
0
38
329
1.61
0.70
8.8
4.9
45.82
39.52
mmol/mol
1.53
33
300
0
23
0.00
0.60
0.0
1.6
—
—
—
0
0
28
236
1.41
0.52
3.4
3.2
—
—
—
0
0
22
180
1.39
0.47
7.0
4.0
0.00
0.00
estimate
—
7
38
22
181
1.38
0.45
4.2
2.4
—
—
—
0
0
38
342
1.44
0.45
4.1
3.7
1.39
1.25
mmol/l
0.59
33
314
18
149
1.32
0.34
7.2
4.0
—
—
—
0
0
21
179
1.29
0.32
11.9
5.6
0.00
0.00
estimate
—
6
34
21
182
1.26
0.27
7.0
4.0
0.00
0.00
estimate
—
5
35
5
37
1.39
0.24
4.6
1.3
—
—
—
0
0
5
38
1.35
0.24
4.8
1.3
—
—
—
0
0
12
98
1.29
0.24
2.5
4.7
2.34
1.93
ug/l
0.21
12
87
42
398
1.31
0.23
38.1
14.5
86.40
75.60
umol/l
0.69
42
398
0
11
0.00
0.21
0.0
2.5
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
1.44
—
0
5
0
13
0.00
0.21
0.0
1.2
—
404.16
—
0
5
12
104
1.20
0.14
4.6
4.0
0.00
0.00
estimate
—
6
33
5
47
1.07
0.10
2.0
2.1
—
—
—
0
0
9
84
1.09
0.07
1.0
1.5
—
—
—
0
0
33
332
0.98
0.00
41.3
14.9
14.93
14.95
%
0.01
33
325
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
53
0.94
-0.00
1.0
1.3
—
—
—
0
0
5
53
0.94
-0.00
2.2
2.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
4.43
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
8.00
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
11.39
—
0
7
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint E4_VIT_NAS_DEF and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_VIT_NAS_DEF | 1.706 [0.86, 3.38] | 0.125 |
| Birth year | 0.987 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 52 out of 118 males with E4_VIT_NAS_DEF died.
Mortality risk
Mortality risk for people of age
years, who have E4_VIT_NAS_DEF.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.391% |
| 5 | No data | 1.968% |
| 10 | No data | 5.044% |
| 15 | No data | 9.336% |
| 20 | No data | 15.5% |
Relationships between endpoints
↥Index endpoint: E4_VIT_NAS_DEF – Deficiency of other/unspecified vitamins
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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