Inflammatory myopathy

G6_INFLAMYOP

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — G72.4 Cause of death: ICD-10 — G72.4 2 out of 7 registries used, show all original rules.	74
4. Check minimum number of events None	74
5. Include endpoints None	74
6. Filter based on genotype QC (FinnGen only)	66

Control definitions (FinnGen only)

Control exclude: G6_MYONEU

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: G72
Name in latin: Myopathia inflammatoria non alibi classificata

NAME	G6_INFLAMYOP
CONTROL_EXCLUDE	G6_MYONEU
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	G724
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	G724
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Inflammatory myopathy based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	383	177	205
Only index persons	356	166	190
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	72.29	72.78	71.86
Only index persons	72.51	73.14	71.96

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	66	31	35
Unadjusted period prevalence (%)	0.01	0.01	0.02
Median age at first event (years)	74.96	73.95	75.86

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
66: Matched controls
660

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

G72.4

ICD-10 Finland

Inflammatory myopathy, not elsewhere classified

+∞

91.9

M60.8

ICD-10 Finland

Other myositis

535.2

32.9

G72.9

ICD-10 Finland

Myopathy, unspecified

+∞

24.5

R13

ICD-10 Finland

Dysphagia

12.5

22.3

M60.9

ICD-10 Finland

Myositis, unspecified

261.3

19.7

NXL00

NOMESCO Finland

Biopsy of muscle

+∞

16.3

JC2KB

NOMESCO Finland

Functional X-ray examination of swallowing

207.1

16.2

G72.8

ICD-10 Finland

Other specified myopathies

190.5

15.1

L28

ICPC

Limited function/disability (L)

6.8

13.9

M33.2

ICD-10 Finland

Polymyositis

129.8

10.8

JDB10

NOMESCO Finland

Percutaneous gastrostomy

64.9

10.0

SPAT1229

SPAT

Assessment of need for aid

8.5

8.9

J69.0

ICD-10 Finland

Pneumonitis due to food and vomit

24.0

8.8

L19

ICPC

Muscle symptom/complaint NOS

20.5

8.4

N28

ICPC

Limited function/disability (N)

25.9

8.3

GD1QA

NOMESCO Finland

Supine thorax X-ray examination

4.4

8.0

111

JCA55

NOMESCO Finland

Endoscopic dilatation of oesophagus

51.3

7.9

N18

ICPC

Paralysis/weakness

15.9

7.7

NJ3BG

NOMESCO Finland

MRI examination of extremities with high intensity magnet

89.8

7.6

NJ3CG

NOMESCO Finland

Extensive MRI examination of extremities with median high magnet

+∞

7.4

SPAT1223

SPAT

Implementation of physical therapy rehabilitation plan

4.0

7.2

153

SPAT1230

SPAT

Aid fitting and borrowing and monitoring of use

4.2

6.9

SPAT1215

SPAT

Assessment of need for medical rehabilitation

9.8

6.7

L04AX01

ATC

azathioprine; systemic

16.5

6.6

504

Kela drug reimbursment

Conditions requiring daily forced enteral nutrition

20.5

6.5

TJD20

NOMESCO Finland

Change of gastrostomy tube

+∞

6.3

K22.4

ICD-10 Finland

Dyskinesia of oesophagus

+∞

6.3

M62.9

ICD-10 Finland

Disorder of muscle, unspecified

+∞

6.3

L99

ICPC

Musculoskeletal disease other

14.4

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(4035726) Immunohistochemistry procedure

6.56

12.14

1.5

1.3

—

(3037522) Nuclear Ab [Titer] in Serum

3.70

5.25

1.7

1.3

457.14

583.33

titre

—

(3022313) Gas panel - Capillary blood

5.63

5.04

4.1

5.8

—

(42870588) Differential panel, method unspecified - Blood

197

3.00

4.59

9.4

5.6

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

5.86

4.58

1.8

—

(3001604) Monocytes [#/volume] in Blood

288

3.20

4.49

7.3

6.0

0.66

0.62

e9/l

0.73

244

(3006315) Basophils [#/volume] in Blood

291

3.14

4.35

7.7

6.0

0.04

e9/l

0.50

244

(3004616) Nuclear Ab [Presence] in Serum

8.91

4.19

1.1

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

5.19

4.18

1.8

2.3

—

(3019309) Folate [Moles/volume] in Red Blood Cells

142

2.86

4.09

2.6

1.7

1127.11

1268.90

nmol/l

0.32

104

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

116

2.86

3.86

2.3

2.1

—

(3023368) Bacteria identified in Blood by Culture

195

2.53

3.37

5.2

4.6

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

233

2.49

3.22

3.8

3.9

1264.95

1837.06

ng/l

0.67

189

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

323

2.58

3.05

8.3

9.1

1.22

1.21

mmol/l

0.24

277

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

154

2.42

2.96

1.9

1.8

464.81

442.14

pmol/l

0.14

125

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

336

2.57

2.95

6.3

6.7

10.53

12.38

umol/l

0.98

319

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

2.59

2.58

5.9

32.50

33.18

0.09

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

297

2.29

2.57

9.0

7.9

1.21

mmol/l

0.00

267

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

3.38

2.48

1.9

1.5

—

(3001334) Neutrophil cytoplasmic Ab [Units/volume] in Serum

3.99

2.45

1.7

1.1

—

(3027315) Oxygen [Partial pressure] in Blood

6.65

2.41

3.2

3.6

7.92

7.94

kpa

—

(3013290) Carbon dioxide [Partial pressure] in Blood

6.65

2.41

3.2

3.6

5.40

5.04

kpa

—

(3032080) INR in Blood by Coagulation assay

304

2.19

2.33

17.5

14.8

1.29

1.28

inr

0.02

251

(3009445) Proteinase 3 Ab [Units/volume] in Serum

3.43

2.33

1.6

1.1

—

(3045414) Leukocytes [Presence] in Urine

2.70

2.29

2.0

2.1

—

0.00

estimate

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

5.90

2.25

1.2

1.4

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

269

2.10

2.22

2.5

75.62

80.26

nmol/l

0.44

224

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

171

2.11

2.19

3.3

2.8

44.87

44.39

u/l

0.02

162

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

156

2.10

2.12

2.2

2.8

—

(3010421) pH of Blood

4.29

2.09

4.0

7.44

7.40

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

174

2.06

2.07

2.7

2.1

2.83

2.90

mg/l

0.05

152

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

4.01

1.98

1.0

1.4

—

(3013707) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method

432

2.38

1.98

7.5

4.5

18.74

14.61

mm/h

0.88

383

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.61

1.89

2.0

2.2

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.49

1.87

1.6

2.3

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

4.41

1.86

1.4

1.2

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

262

1.94

1.84

2.6

2.5

—

(3013512) EKG study

225

1.93

1.83

5.5

4.6

—

(40768804) Tissue Pathology biopsy report

228

1.89

1.74

2.2

2.1

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

3.36

1.70

1.7

1.1

—

(3005719) IgG [Mass/volume] in Serum or Plasma

2.56

1.68

3.3

2.0

11.61

10.20

g/l

—

(3042631) Mycobacterium sp identified in Specimen

3.77

1.64

3.4

3.6

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.25

1.62

1.8

1.6

—

(3012110) Lysozyme [Mass/volume] in Serum or Plasma

3.29

1.46

1.4

1.5

19.24

12.06

mg/l

—

(3041096) Erythrocytes [Presence] in Urine by Automated

183

1.80

1.46

3.7

3.8

0.00

estimate

—

(3037756) Immunofixation for Serum or Plasma

3.09

1.38

1.4

—

(3021960) Folate [Moles/volume] in Serum or Plasma

204

1.75

1.37

2.1

1.7

22.69

21.94

nmol/l

0.08

159

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

341

1.75

1.30

5.2

3.1

63.08

52.85

u/l

0.20

316

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.94

1.28

2.3

2.0

—

(3044640) Blood type and Crossmatch panel - Blood

207

1.72

1.28

2.7

—

(40768797) Stomach Pathology biopsy report

1.95

1.25

1.3

—

(3042936) Bacteria identified in Isolate by Culture

1.89

1.20

3.9

2.0

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

221

1.66

1.16

3.2

3.6

—

(3026008) Bacteria identified in Urine by Culture

213

1.64

1.12

2.9

3.5

—

(3035350) Ketones [Presence] in Urine by Test strip

319

1.64

1.12

3.4

4.3

0.00

estimate

—

(40760892) CBC W Ordered Manual Differential panel - Blood

116

1.76

1.11

4.8

5.0

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

425

1.73

1.06

4.3

14.93

15.18

pmol/l

0.27

366

(40761536) Microorganisms panel - Urine sediment

1.97

1.04

3.8

4.5

—

(3009261) Glucose [Presence] in Urine by Test strip

323

1.61

1.03

3.8

4.4

0.00

estimate

—

(3025941) Bacteria identified in Stool by Culture

0.00

1.00

0.0

1.5

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.00

1.00

0.0

1.9

—

3.16

—

(3007164) IgA [Mass/volume] in Serum or Plasma

120

1.69

0.99

1.8

1.4

3.32

2.43

g/l

—

(3015736) pH of Urine

247

1.57

0.99

3.0

4.0

6.09

6.22

0.34

135

(3026493) Urate [Moles/volume] in Serum or Plasma

164

1.62

0.98

2.1

3.2

365.65

355.89

umol/l

0.13

133

(3021601) Nitrite [Presence] in Urine by Test strip

316

1.57

0.97

3.5

4.4

0.00

estimate

—

(36304419) Bacteria [Presence] in Urine

165

1.60

0.96

3.2

—

estimate

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

2.25

0.94

1.5

1.8

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

2.03

0.87

1.7

1.9

—

(3030467) Casts [#/volume] in Urine by Automated count

180

1.52

0.81

3.3

0.47

0.31

e6/l

0.23

138

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.71

0.74

5.8

3.7

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.79

0.72

3.7

11.7

29.39

24.85

mmol/l

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.72

0.69

1.8

1.5

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.85

0.67

1.0

—

(3003338) MCHC [Entitic Mass/volume] in Red Blood Cells

406

0.71

0.65

33.7

25.7

328.91

331.42

g/l

0.98

406

(40761511) CBC panel - Blood by Automated count

545

1.78

0.65

31.1

17.3

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.59

0.62

2.6

2.0

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.00

0.61

0.0

1.2

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

296

1.39

0.60

2.4

2.1

89.72

89.27

pmol/l

0.02

139

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.58

0.58

1.9

1.7

—

(3002256) Pathology report gross observation

1.58

0.58

1.1

1.2

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.61

0.56

3.0

2.1

321.70

429.34

nmol/l

—

(3018095) Leukocytes [#/volume] in Urine

230

1.38

0.56

3.5

4.4

58.90

108.58

e6/l

0.47

174

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

495

1.50

0.55

4.7

1.38

1.24

mmol/l

0.92

434

(40764999) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M

517

1.55

0.55

23.9

20.4

91.30

73.32

ml/min/173m2

5.55

479

(3044889) 12 lead EKG panel

400

0.73

0.54

5.0

4.6

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

519

1.52

0.52

5.1

5.7

4.23

4.39

mmol/l

0.51

463

(36660697) Celiac disease serology panel - Serum

1.58

0.50

1.1

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

244

1.34

0.49

4.0

4.4

0.00

estimate

—

(3019060) Gas panel - Arterial blood

1.45

0.47

13.7

3.3

—

(3022145) Colonoscopy Study observation

1.45

0.47

1.3

1.2

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.47

0.44

1.8

1.9

—

(40758558) Short blood count panel - Blood

189

0.73

0.42

9.5

6.2

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

514

1.42

0.42

5.9

5.4

2.05

2.10

mu/l

0.15

447

(3019230) Fractional oxyhemoglobin in Venous blood

0.00

0.41

0.0

2.8

—

52.31

—

(3001019) Free T4 and TSH panel - Serum or Plasma

0.00

0.41

0.0

1.1

—

(3019977) pH of Arterial blood

1.43

0.41

11.2

8.7

7.41

7.42

—

(42868678) Cholesterol non HDL [Moles/volume] in Serum or Plasma

0.00

0.40

0.0

1.7

—

3.44

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

517

1.38

0.37

5.5

5.6

1.38

1.47

mmol/l

0.78

454

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.37

0.35

1.2

1.6

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.37

0.35

2.3

1.4

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

102

1.34

0.33

3.2

3.3

0.12

0.94

e6/l

—

(3029937) Albumin [Presence] in Urine by Test strip

187

1.26

0.32

3.3

4.3

0.00

estimate

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

285

1.24

0.31

3.7

3.0

—

estimate

—

(3021589) Normoblasts [#/volume] in Blood

246

1.24

0.31

18.9

13.4

0.00

e9/l

0.74

198

(3000991) Gas panel - Venous blood

1.31

0.29

4.8

13.4

—

(1761868) Lipid panel - Serum or Plasma

159

0.77

0.29

2.4

3.7

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

533

1.33

0.28

6.1

5.8

6.03

6.08

mmol/l

0.11

467

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.25

0.27

13.3

7.9

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

537

1.28

0.23

5.9

6.6

2.45

2.51

mmol/l

0.21

474

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.21

0.22

1.6

1.5

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.21

0.0

4.5

—

80.64

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.21

0.0

1.3

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.21

0.0

1.2

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

0.21

0.0

4.8

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.21

0.0

1.3

—

17.60

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.21

0.0

1.1

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.26

0.21

3.2

3.5

0.40

1.34

e6/l

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

2.0

—

16.69

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.21

0.0

1.2

—

(40761535) Cells panel - Urine sediment

1.27

0.21

1.3

3.8

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

0.21

0.0

1.3

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

0.00

0.21

0.0

1.2

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

0.00

0.21

0.0

1.2

—

(42529406) Shigella sp [Presence] in Stool by Culture

0.00

0.21

0.0

1.2

—

(3018418) pH of Serum or Plasma

205

1.19

0.21

6.0

5.1

7.41

7.40

0.53

142

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.00

0.20

0.0

3.2

—

(3050449) Albumin [Mass/time] in Urine collected for unspecified duration

0.00

0.20

0.0

2.0

—

140.37

—

(3009508) Creatinine [Moles/volume] in Urine

226

1.17

0.19

2.5

3.5

6.11

7.30

mmol/l

0.54

185

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

520

1.21

0.17

7.9

7.4

39.52

40.46

mmol/mol

0.47

473

(3000494) Fungus identified in Specimen by Culture

1.16

0.17

3.9

1.5

—

(3020682) Albumin/Creatinine [Ratio] in Urine

229

1.15

0.15

3.2

4.3

14.82

8.11

mg/mmol

0.24

148

(3012516) Albumin [Mass/volume] in Urine

223

1.12

0.11

2.5

3.5

87.43

48.48

mg/l

0.24

145

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

1.07

0.09

1.6

1.4

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.79

0.08

1.2

1.3

—

(3003694) ABO and Rh group [Type] in Blood

147

1.03

0.00

1.5

1.4

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

178

1.02

0.00

5.3

5.7

23.03

23.13

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.0

1.0

—

(44806420) Estimation of glomerular filtration rate

0.00

0.0

2.2

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.0

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.0

—

(21494815) CD4 cells/Lymphocytes in Specimen

0.00

0.0

1.8

—

36.26

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

0.0

1.2

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.5

—

1.08

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.0

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.0

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

0.0

2.4

—

4.20

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.5

—

1.62

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

2.2

—

9.42

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

0.0

3.0

—

(3022756) Ceruloplasmin [Mass/volume] in Serum or Plasma

0.00

0.0

1.0

—

259.20

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.2

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.0

1.3

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

2.2

—

4.69

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.0

—

(40758292) HTLV I+II Ab panel - Serum

0.00

0.0

1.6

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.0

—

(4281824) Cell count and differential, peritoneal fluid

0.00

0.0

1.0

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

100

1.00

-0.00

3.9

8.6

102.40

103.62

mmol/l

—

100

(3036603) Volume of Urine

0.00

-0.00

0.0

1.1

—

1318.57

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.4

—

(21494434) Karyotype in Bone marrow

0.00

-0.00

0.0

1.0

—

(3011648) Oxygen content in Venous blood

0.00

-0.00

0.0

2.4

—

10.83

—

(3002032) Base excess in Venous blood by calculation

0.98

-0.00

2.3

5.4

2.73

1.14

mmol/l

—

(3020148) Glutamate decarboxylase 65 Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

-0.00

0.0

1.0

—

(3025130) Human papilloma virus identified in Specimen

0.00

-0.00

0.0

2.0

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

-0.00

0.0

1.5

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

-0.00

0.0

1.9

—

8.96

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

-0.00

0.0

1.5

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.4

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

-0.00

0.0

1.6

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.02

-0.00

1.4

1.3

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

-0.00

0.0

1.3

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

-0.00

0.0

1.2

—

750.00

—

(3000034) Microalbumin [Mass/volume] in Urine

0.00

-0.00

0.0

4.3

—

42.03

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.4

—

Mortality – FinRegistry

↥

Association

Association between endpoint G6_INFLAMYOP and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have G6_INFLAMYOP.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: G6_INFLAMYOP – Inflammatory myopathy

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Inflammatory myopathy

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints